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GSE58827: Dynamics of the Mouse Liver

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Results for Tfcp2

Z-value: 1.74

Motif logo

Transcription factors associated with Tfcp2

Gene Symbol Gene ID Gene Info
ENSMUSG00000009733.8 transcription factor CP2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tfcp2mm10_v2_chr15_-_100551959_1005520100.325.5e-02Click!

Activity profile of Tfcp2 motif

Sorted Z-values of Tfcp2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_75571522 16.60 ENSMUST00000143226.1
ENSMUST00000124259.1
gamma-glutamyltransferase 1
chr8_+_57511833 16.03 ENSMUST00000067925.6
high mobility group box 2
chr19_-_34166037 13.74 ENSMUST00000025686.7
ankyrin repeat domain 22
chr8_+_94172618 13.02 ENSMUST00000034214.6
metallothionein 2
chr10_+_43579161 12.61 ENSMUST00000058714.8
CD24a antigen
chr17_-_48451510 12.51 ENSMUST00000024794.5
translocator protein 2
chr7_+_96211656 12.31 ENSMUST00000107165.1
teneurin transmembrane protein 4
chr11_+_116532441 11.34 ENSMUST00000106386.1
ENSMUST00000145737.1
ENSMUST00000155102.1
ENSMUST00000063446.6
sphingosine kinase 1
chr5_+_106964319 10.85 ENSMUST00000031221.5
ENSMUST00000117196.2
ENSMUST00000076467.6
cell division cycle 7 (S. cerevisiae)
chr11_-_99438143 10.64 ENSMUST00000017743.2
keratin 20
chr3_-_90695706 10.36 ENSMUST00000069960.5
ENSMUST00000117167.1
S100 calcium binding protein A9 (calgranulin B)
chr11_+_69045640 9.80 ENSMUST00000108666.1
ENSMUST00000021277.5
aurora kinase B
chr15_+_89322969 9.46 ENSMUST00000066991.5
adrenomedullin 2
chrX_+_73639414 9.26 ENSMUST00000019701.8
dual specificity phosphatase 9
chr17_+_28207778 9.15 ENSMUST00000002327.5
differentially expressed in FDCP 6
chr11_+_11487671 8.52 ENSMUST00000020410.4
RIKEN cDNA 4930415F15 gene
chrX_-_102250940 8.40 ENSMUST00000134887.1
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
chr8_+_3665747 8.39 ENSMUST00000014118.2
RIKEN cDNA 1810033B17 gene
chr15_-_103537928 8.12 ENSMUST00000023133.6
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr6_+_134929089 7.78 ENSMUST00000183867.1
ENSMUST00000184991.1
ENSMUST00000183905.1
RP23-45G16.5
chr9_-_67832325 7.66 ENSMUST00000054500.5
C2 calcium-dependent domain containing 4A
chr6_+_134929118 7.64 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5
chr6_+_5390387 7.29 ENSMUST00000183358.1
ankyrin repeat and SOCS box-containing 4
chr13_-_100786402 6.80 ENSMUST00000174038.1
ENSMUST00000091295.7
ENSMUST00000072119.8
cyclin B1
chr4_-_154025657 6.50 ENSMUST00000146426.1
small integral membrane protein 1
chr1_+_107511489 6.34 ENSMUST00000064916.2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr5_+_33658550 6.33 ENSMUST00000152847.1
transforming, acidic coiled-coil containing protein 3
chr4_-_154025867 6.24 ENSMUST00000130175.1
ENSMUST00000182151.1
small integral membrane protein 1
chr1_+_107511416 6.21 ENSMUST00000009356.4
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr12_+_24708984 6.04 ENSMUST00000154588.1
ribonucleotide reductase M2
chr6_+_127887582 5.91 ENSMUST00000032501.4
tetraspanin 11
chr4_-_154025926 5.82 ENSMUST00000132541.1
ENSMUST00000143047.1
small integral membrane protein 1
chr11_-_95914884 5.74 ENSMUST00000038343.6
beta-1,4-N-acetyl-galactosaminyl transferase 2
chr14_-_37110087 5.63 ENSMUST00000179488.1
RIKEN cDNA 2610528A11 gene
chrX_-_102250775 5.55 ENSMUST00000130589.1
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
chr4_-_49593875 5.55 ENSMUST00000151542.1
transmembrane protein 246
chr5_+_33658567 5.27 ENSMUST00000114426.3
transforming, acidic coiled-coil containing protein 3
chr11_+_96929260 5.27 ENSMUST00000054311.5
ENSMUST00000107636.3
proline rich 15-like
chr17_-_25727364 5.06 ENSMUST00000170070.1
ENSMUST00000048054.7
CTF18, chromosome transmission fidelity factor 18
chr11_+_23256001 4.86 ENSMUST00000020538.6
ENSMUST00000109551.1
ENSMUST00000102870.1
ENSMUST00000102869.1
exportin 1, CRM1 homolog (yeast)
chr13_+_91461050 4.82 ENSMUST00000004094.8
ENSMUST00000042122.8
single-stranded DNA binding protein 2
chr2_+_85136355 4.82 ENSMUST00000057019.7
apelin receptor
chr1_+_130731963 4.79 ENSMUST00000039323.6
expressed sequence AA986860
chr19_-_40588374 4.78 ENSMUST00000175932.1
ENSMUST00000176955.1
ENSMUST00000149476.2
aldehyde dehydrogenase 18 family, member A1
chr4_-_154025616 4.77 ENSMUST00000182191.1
ENSMUST00000146543.2
small integral membrane protein 1
chr7_-_4546567 4.69 ENSMUST00000065957.5
synaptotagmin V
chr19_-_40588453 4.66 ENSMUST00000025979.6
aldehyde dehydrogenase 18 family, member A1
chr15_-_74734313 4.60 ENSMUST00000023260.3
Ly6/Plaur domain containing 2
chrX_-_164076100 4.56 ENSMUST00000037928.2
ENSMUST00000071667.2
seven in absentia 1B
chr19_-_40588338 4.40 ENSMUST00000176939.1
aldehyde dehydrogenase 18 family, member A1
chr4_-_133967893 4.33 ENSMUST00000100472.3
ENSMUST00000136327.1
high mobility group nucleosomal binding domain 2
chr1_-_87156127 4.13 ENSMUST00000160810.1
endothelin converting enzyme-like 1
chr11_+_69914179 4.12 ENSMUST00000057884.5
G protein pathway suppressor 2
chr9_+_124102110 4.09 ENSMUST00000168841.1
ENSMUST00000055918.6
chemokine (C-C motif) receptor 2
chr18_+_11633276 4.05 ENSMUST00000115861.2
retinoblastoma binding protein 8
chr7_-_45333754 3.90 ENSMUST00000042194.8
transient receptor potential cation channel, subfamily M, member 4
chr3_-_55055038 3.81 ENSMUST00000029368.2
cyclin A1
chr11_+_3895223 3.79 ENSMUST00000055931.4
ENSMUST00000109996.1
dual specificity phosphatase 18
chr8_+_69822429 3.77 ENSMUST00000164890.1
ENSMUST00000034325.4
lysophosphatidic acid receptor 2
chr14_-_73325773 3.72 ENSMUST00000022701.6
retinoblastoma 1
chr2_-_168010618 3.71 ENSMUST00000099073.2
family with sequence similarity 65, member C
chr14_-_76556662 3.62 ENSMUST00000064517.7
stress-associated endoplasmic reticulum protein family member 2
chr1_-_52190901 3.60 ENSMUST00000156887.1
ENSMUST00000129107.1
glutaminase
chr2_+_26628441 3.54 ENSMUST00000074240.3
family with sequence similarity 69, member B
chr15_-_73184840 3.44 ENSMUST00000044113.10
argonaute RISC catalytic subunit 2
chr9_+_50856924 3.42 ENSMUST00000174628.1
ENSMUST00000034560.7
ENSMUST00000114437.2
ENSMUST00000175645.1
ENSMUST00000176349.1
ENSMUST00000176798.1
ENSMUST00000175640.1
protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform
chrX_-_37085402 3.37 ENSMUST00000115231.3
ribosomal protein L39
chr18_+_60925612 3.33 ENSMUST00000102888.3
ENSMUST00000025519.4
calcium/calmodulin-dependent protein kinase II alpha
chr14_+_75136475 3.26 ENSMUST00000122840.1
lymphocyte cytosolic protein 1
chr4_-_116167591 3.23 ENSMUST00000030465.3
ENSMUST00000143426.1
tetraspanin 1
chr4_-_133967953 3.21 ENSMUST00000102553.4
high mobility group nucleosomal binding domain 2
chr11_+_50376982 3.15 ENSMUST00000109142.1
heterogeneous nuclear ribonucleoprotein H1
chr3_+_122729158 3.12 ENSMUST00000066728.5
phosphodiesterase 5A, cGMP-specific
chrX_-_75130914 3.10 ENSMUST00000114091.1
membrane protein, palmitoylated
chr9_+_124101944 3.09 ENSMUST00000171719.1
chemokine (C-C motif) receptor 2
chr19_-_38043559 3.06 ENSMUST00000041475.8
ENSMUST00000172095.2
myoferlin
chrX_-_75130996 2.97 ENSMUST00000033775.2
membrane protein, palmitoylated
chr15_-_79164477 2.94 ENSMUST00000040019.4
SRY-box containing gene 10
chr17_-_24527925 2.93 ENSMUST00000176652.1
TNF receptor-associated factor 7
chrX_+_6779306 2.90 ENSMUST00000067410.7
diacylglycerol kinase kappa
chr16_-_32810477 2.83 ENSMUST00000179384.2
predicted gene 933
chr17_-_24527830 2.81 ENSMUST00000176353.1
ENSMUST00000176237.1
TNF receptor-associated factor 7
chr1_-_149961230 2.79 ENSMUST00000070200.8
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr19_-_60861390 2.69 ENSMUST00000135808.1
sideroflexin 4
chr2_-_51934943 2.69 ENSMUST00000102767.1
ENSMUST00000102768.1
RNA binding motif protein 43
chr3_-_102964124 2.57 ENSMUST00000058899.8
nuclear receptor subfamily 1, group H, member 5
chr8_+_120488416 2.55 ENSMUST00000034279.9
genetic suppressor element 1
chr1_+_58210397 2.51 ENSMUST00000040442.5
aldehyde oxidase 4
chr10_+_80019621 2.50 ENSMUST00000043311.6
histocompatibility (minor) HA-1
chr2_+_84798828 2.47 ENSMUST00000102642.2
ENSMUST00000150325.1
ubiquitin-conjugating enzyme E2L 6
chr2_-_180334665 2.45 ENSMUST00000015771.2
GATA binding protein 5
chr5_-_129787175 2.42 ENSMUST00000031399.6
phosphoserine phosphatase
chr8_-_110846770 2.40 ENSMUST00000042012.5
splicing factor 3b, subunit 3
chrX_+_56779437 2.40 ENSMUST00000114773.3
four and a half LIM domains 1
chr5_+_114786045 2.40 ENSMUST00000137519.1
ankyrin repeat domain 13a
chr11_+_48800357 2.38 ENSMUST00000020640.7
guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1
chr8_+_121730563 2.31 ENSMUST00000026357.5
junctophilin 3
chr6_+_122990367 2.29 ENSMUST00000079379.2
C-type lectin domain family 4, member a4
chr13_-_76018524 2.29 ENSMUST00000050997.1
ENSMUST00000179078.1
ENSMUST00000167271.1
Rieske (Fe-S) domain containing
chr10_+_127048235 2.26 ENSMUST00000165764.1
cytochrome P450, family 27, subfamily b, polypeptide 1
chr17_+_35059035 2.21 ENSMUST00000007255.6
ENSMUST00000174493.1
dimethylarginine dimethylaminohydrolase 2
chr15_-_100424208 2.20 ENSMUST00000154331.1
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr3_+_95622236 2.19 ENSMUST00000074353.4
ribosomal protein S10, pseudogene 1
chr19_-_29367294 2.16 ENSMUST00000138051.1
plasminogen receptor, C-terminal lysine transmembrane protein
chr14_+_75136326 2.14 ENSMUST00000145303.1
lymphocyte cytosolic protein 1
chr19_-_36919606 2.11 ENSMUST00000057337.7
fibroblast growth factor binding protein 3
chr1_-_133690100 2.10 ENSMUST00000169295.1
lymphocyte transmembrane adaptor 1
chr16_-_3907651 2.09 ENSMUST00000177221.1
ENSMUST00000177323.1
RIKEN cDNA 1700037C18 gene
chr7_-_35396708 2.08 ENSMUST00000154597.1
ENSMUST00000032704.5
RIKEN cDNA C230052I12 gene
chr15_-_11905609 2.08 ENSMUST00000066529.3
natriuretic peptide receptor 3
chr4_+_115088708 1.99 ENSMUST00000171877.1
ENSMUST00000177647.1
ENSMUST00000106548.2
ENSMUST00000030488.2
PDZK1 interacting protein 1
chr19_+_34100943 1.95 ENSMUST00000025685.6
lipase, family member M
chr1_+_44551483 1.94 ENSMUST00000074525.3
GULP, engulfment adaptor PTB domain containing 1
chr5_-_30073554 1.93 ENSMUST00000026846.6
thymidylate synthase
chr17_+_34593388 1.91 ENSMUST00000174532.1
pre B cell leukemia homeobox 2
chr15_-_100424092 1.89 ENSMUST00000154676.1
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr7_+_141447645 1.89 ENSMUST00000106004.1
ENSMUST00000106003.1
ribosomal protein, large P2
chr2_-_148443543 1.84 ENSMUST00000099269.3
CD93 antigen
chr11_-_45955465 1.84 ENSMUST00000011398.6
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr14_-_54994541 1.82 ENSMUST00000153783.1
ENSMUST00000168485.1
ENSMUST00000102803.3
myosin, heavy polypeptide 7, cardiac muscle, beta
chr1_+_165302625 1.78 ENSMUST00000111450.1
G protein-coupled receptor 161
chr9_-_21037775 1.78 ENSMUST00000180870.1
predicted gene, 26592
chr12_+_78861693 1.75 ENSMUST00000071230.7
eukaryotic translation initiation factor 2, subunit 1 alpha
chr9_-_109234754 1.70 ENSMUST00000079548.6
F-box and WD-40 domain protein 20
chrX_-_10216437 1.69 ENSMUST00000115534.1
retinitis pigmentosa GTPase regulator
chr7_+_131032061 1.66 ENSMUST00000084509.3
deleted in malignant brain tumors 1
chr5_-_100500592 1.65 ENSMUST00000149714.1
ENSMUST00000046154.5
lin-54 homolog (C. elegans)
chr14_+_30479565 1.64 ENSMUST00000022535.7
DCP1 decapping enzyme homolog A (S. cerevisiae)
chr8_-_35826435 1.63 ENSMUST00000060128.5
claudin 23
chr18_+_65582390 1.56 ENSMUST00000169679.1
ENSMUST00000183326.1
zinc finger protein 532
chr19_+_29367447 1.55 ENSMUST00000016640.7
CD274 antigen
chr17_+_7170101 1.54 ENSMUST00000024575.6
ribosomal protein S6 kinase, polypeptide 2
chr11_+_3289880 1.50 ENSMUST00000110043.1
ENSMUST00000094471.3
POZ (BTB) and AT hook containing zinc finger 1
chr11_-_45955183 1.50 ENSMUST00000109254.1
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr6_-_57844493 1.49 ENSMUST00000081186.3
vomeronasal 1 receptor 21
chr3_+_92365178 1.49 ENSMUST00000050397.1
small proline-rich protein 2F
chr18_+_65582239 1.47 ENSMUST00000182684.1
zinc finger protein 532
chrX_+_7841800 1.46 ENSMUST00000033494.9
ENSMUST00000115666.1
OTU domain containing 5
chr2_+_16356744 1.46 ENSMUST00000114703.3
plexin domain containing 2
chr19_-_55241236 1.43 ENSMUST00000069183.6
guanylate cyclase 2g
chr7_+_113514085 1.39 ENSMUST00000122890.1
fatty acyl CoA reductase 1
chrX_+_74254736 1.34 ENSMUST00000096424.4
emerin
chr6_-_92244645 1.33 ENSMUST00000006046.4
thyrotropin releasing hormone
chr11_-_96111962 1.32 ENSMUST00000097162.5
ENSMUST00000068686.6
calcium binding and coiled-coil domain 2
chr7_-_126200413 1.31 ENSMUST00000163959.1
exportin 6
chrX_-_7572843 1.30 ENSMUST00000132788.1
protein phosphatase 1, regulatory (inhibitor) subunit 3F
chr5_-_110343009 1.29 ENSMUST00000058016.9
ENSMUST00000112478.3
purinergic receptor P2X, ligand-gated ion channel, 2
chr7_+_35397046 1.28 ENSMUST00000079414.5
centrosomal protein 89
chr7_-_126594941 1.28 ENSMUST00000058429.5
interleukin 27
chr19_+_5568002 1.21 ENSMUST00000096318.3
adaptor-related protein complex 5, beta 1 subunit
chr2_+_127854628 1.20 ENSMUST00000028859.1
acyl-Coenzyme A oxidase-like
chrX_+_56346390 1.19 ENSMUST00000101560.3
zinc finger protein 449
chr1_-_162740540 1.17 ENSMUST00000028016.9
ENSMUST00000182660.1
proline-rich coiled-coil 2C
chr9_-_99358518 1.15 ENSMUST00000042158.6
extended synaptotagmin-like protein 3
chr4_-_153482768 1.14 ENSMUST00000105646.2
adherens junction associated protein 1
chr10_-_130127055 1.11 ENSMUST00000074161.1
olfactory receptor 824
chr11_-_78751656 1.09 ENSMUST00000059468.4
family with sequence similarity 58, member B
chr14_-_79481268 1.05 ENSMUST00000022601.5
WW domain binding protein 4
chrX_+_138914422 1.04 ENSMUST00000064937.7
ENSMUST00000113052.1
Nik related kinase
chr9_+_35423582 1.03 ENSMUST00000154652.1
cell adhesion molecule-related/down-regulated by oncogenes
chr8_-_60954726 1.03 ENSMUST00000110302.1
chloride channel 3
chr6_-_116716888 1.01 ENSMUST00000056623.6
transmembrane protein 72
chr5_+_145114280 1.00 ENSMUST00000141602.1
actin related protein 2/3 complex, subunit 1B
chr1_-_85109846 0.99 ENSMUST00000161675.1
ENSMUST00000160792.1
RIKEN cDNA A530032D15Rik gene
chr3_-_41742471 0.99 ENSMUST00000026866.8
sodium channel and clathrin linker 1
chr15_-_75909319 0.99 ENSMUST00000089680.3
ENSMUST00000141268.1
ENSMUST00000023235.6
ENSMUST00000109972.2
ENSMUST00000089681.5
ENSMUST00000109975.3
ENSMUST00000154584.1
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chrX_-_48594373 0.99 ENSMUST00000088898.4
ENSMUST00000072292.5
zinc finger protein 280C
chr15_-_75909289 0.96 ENSMUST00000145764.1
ENSMUST00000116440.2
ENSMUST00000151066.1
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chrX_+_74254679 0.96 ENSMUST00000002029.6
emerin
chr2_-_154769932 0.94 ENSMUST00000184654.1
predicted gene 14214
chr17_+_34972687 0.92 ENSMUST00000007248.3
heat shock protein 1-like
chrX_+_7842056 0.89 ENSMUST00000115667.3
ENSMUST00000115668.3
ENSMUST00000115665.1
OTU domain containing 5
chr3_+_84952146 0.89 ENSMUST00000029727.7
F-box and WD-40 domain protein 7
chr15_-_85578070 0.88 ENSMUST00000109424.2
wingless-related MMTV integration site 7B
chr2_+_163225363 0.87 ENSMUST00000099110.3
ENSMUST00000165937.1
TOX high mobility group box family member 2
chr6_-_34317442 0.86 ENSMUST00000154655.1
ENSMUST00000102980.4
aldo-keto reductase family 1, member B3 (aldose reductase)
chr8_+_33599608 0.86 ENSMUST00000009774.9
protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform
chr17_-_65884902 0.85 ENSMUST00000024905.9
ralA binding protein 1
chr2_-_25983056 0.83 ENSMUST00000127823.1
ENSMUST00000134882.1
calmodulin regulated spectrin-associated protein 1
chr11_-_70969953 0.82 ENSMUST00000108530.1
ENSMUST00000035283.4
ENSMUST00000108531.1
nucleoporin 88
chrX_+_52912232 0.81 ENSMUST00000078944.6
ENSMUST00000101587.3
ENSMUST00000154864.2
PHD finger protein 6
chrX_+_74254782 0.81 ENSMUST00000119197.1
ENSMUST00000088313.4
emerin
chr7_-_126200474 0.80 ENSMUST00000168189.1
exportin 6
chr11_-_82829024 0.79 ENSMUST00000021036.6
ENSMUST00000074515.4
ENSMUST00000103218.2
ring finger and FYVE like domain containing protein
chr19_-_45749563 0.78 ENSMUST00000070215.7
nucleoplasmin 3
chr4_-_132422394 0.74 ENSMUST00000152271.1
ENSMUST00000084170.5
phosphatase and actin regulator 4
chr18_+_65582281 0.70 ENSMUST00000183319.1
zinc finger protein 532
chr15_+_54745702 0.69 ENSMUST00000050027.8
nephroblastoma overexpressed gene
chr11_+_102885160 0.69 ENSMUST00000100369.3
family with sequence similarity 187, member A
chr9_+_32372409 0.65 ENSMUST00000047334.8
potassium inwardly-rectifying channel, subfamily J, member 1
chr19_+_6909692 0.62 ENSMUST00000088257.7
tRNA methyltransferase 11-2
chr10_+_62449489 0.61 ENSMUST00000181110.1
RIKEN cDNA 4930507D05 gene
chr16_+_44139821 0.61 ENSMUST00000159514.1
ENSMUST00000161326.1
ENSMUST00000063520.8
ENSMUST00000063542.7
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr4_-_139352538 0.61 ENSMUST00000102503.3
MRT4, mRNA turnover 4, homolog (S. cerevisiae)
chr4_-_141598206 0.60 ENSMUST00000131317.1
ENSMUST00000006381.4
ENSMUST00000129602.1
filamin binding LIM protein 1
chr9_-_109626059 0.60 ENSMUST00000073962.6
F-box and WD-40 domain protein 24
chr8_+_11556061 0.60 ENSMUST00000054399.4
inhibitor of growth family, member 1
chr7_+_101969796 0.60 ENSMUST00000084852.5
nuclear mitotic apparatus protein 1
chr8_+_82863351 0.57 ENSMUST00000078525.5
ring finger protein 150
chr11_+_22990519 0.57 ENSMUST00000173867.1
ENSMUST00000020562.4
chaperonin containing Tcp1, subunit 4 (delta)

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfcp2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 13.8 GO:0006592 ornithine biosynthetic process(GO:0006592)
4.2 12.6 GO:0002842 positive regulation of T cell mediated immune response to tumor cell(GO:0002842)
3.5 10.4 GO:0070488 neutrophil aggregation(GO:0070488)
3.3 9.8 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
3.1 12.3 GO:0060912 cardiac cell fate specification(GO:0060912)
2.8 13.9 GO:0071104 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
2.4 7.2 GO:2000451 immune complex clearance by monocytes and macrophages(GO:0002436) astrocyte chemotaxis(GO:0035700) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451) regulation of astrocyte chemotaxis(GO:2000458)
2.3 16.0 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
2.3 6.8 GO:0031662 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) histone H3-S10 phosphorylation(GO:0043987)
2.1 16.6 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
1.9 11.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
1.9 13.0 GO:0010273 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
1.8 10.9 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
1.6 4.8 GO:0002030 inhibitory G-protein coupled receptor phosphorylation(GO:0002030)
1.3 3.9 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047) positive regulation of actin filament-based movement(GO:1903116)
1.2 3.7 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
1.1 5.7 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.9 3.4 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.8 4.1 GO:0015676 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.8 4.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.8 3.1 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.7 12.2 GO:0030953 astral microtubule organization(GO:0030953)
0.7 5.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.7 7.3 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.6 5.1 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.6 3.6 GO:0006543 glutamine catabolic process(GO:0006543)
0.6 2.4 GO:1905077 negative regulation of interleukin-17 secretion(GO:1905077)
0.6 2.3 GO:0010979 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) positive regulation of response to alcohol(GO:1901421)
0.6 2.8 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.5 2.5 GO:0009115 xanthine catabolic process(GO:0009115)
0.5 2.9 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.5 10.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.5 2.4 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.5 1.9 GO:0046073 dTMP biosynthetic process(GO:0006231) dTMP metabolic process(GO:0046073)
0.5 6.6 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.4 5.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.4 1.7 GO:0072061 inner medullary collecting duct development(GO:0072061)
0.4 10.6 GO:0045109 intermediate filament organization(GO:0045109)
0.4 1.8 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724) slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.3 1.0 GO:0070476 rRNA (guanine-N7)-methylation(GO:0070476)
0.3 1.0 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
0.3 1.0 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.3 5.4 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.3 3.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.3 1.7 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.3 1.7 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.3 2.3 GO:0042126 nitrate metabolic process(GO:0042126)
0.3 1.1 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.3 3.3 GO:0038166 angiotensin-activated signaling pathway(GO:0038166) receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.3 1.3 GO:0001692 histamine metabolic process(GO:0001692)
0.3 2.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.2 2.2 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.2 2.1 GO:0002158 osteoclast proliferation(GO:0002158)
0.2 1.4 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.2 0.7 GO:1990523 negative regulation of SMAD protein import into nucleus(GO:0060392) endothelial cell-cell adhesion(GO:0071603) negative regulation of sensory perception of pain(GO:1904057) bone regeneration(GO:1990523)
0.2 0.6 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.2 1.6 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.2 3.1 GO:0001778 plasma membrane repair(GO:0001778)
0.2 0.8 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.2 2.2 GO:0006527 arginine catabolic process(GO:0006527)
0.2 3.1 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.2 3.4 GO:0002227 innate immune response in mucosa(GO:0002227)
0.2 1.6 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.2 1.5 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.2 6.1 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.2 1.8 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.2 1.3 GO:0030432 peristalsis(GO:0030432)
0.2 2.9 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.2 0.6 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.2 9.4 GO:0045776 negative regulation of blood pressure(GO:0045776)
0.1 1.0 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.1 2.3 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.1 1.3 GO:0045625 regulation of T-helper 1 cell differentiation(GO:0045625)
0.1 4.5 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 2.5 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 4.1 GO:0003016 respiratory system process(GO:0003016)
0.1 1.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 4.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.9 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.6 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.1 1.1 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 1.3 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.1 0.4 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.3 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 1.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 3.8 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 2.3 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.1 4.1 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.1 0.5 GO:0090306 spindle assembly involved in meiosis(GO:0090306)
0.1 0.4 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.1 4.3 GO:0006414 translational elongation(GO:0006414)
0.1 0.5 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 1.0 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 2.4 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1 0.3 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 1.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 5.7 GO:0005977 glycogen metabolic process(GO:0005977) cellular glucan metabolic process(GO:0006073) glucan metabolic process(GO:0044042)
0.0 1.5 GO:0019236 response to pheromone(GO:0019236)
0.0 1.4 GO:0031424 keratinization(GO:0031424)
0.0 0.0 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.0 0.6 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.3 GO:1904871 protein localization to nuclear body(GO:1903405) positive regulation of establishment of protein localization to telomere(GO:1904851) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.0 0.1 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 1.9 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 10.0 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 1.7 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 2.7 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 2.3 GO:0006611 protein export from nucleus(GO:0006611)
0.0 0.9 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 1.4 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.0 0.5 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 1.1 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.2 GO:1901908 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.8 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.5 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.9 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.2 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.3 GO:0019363 pyridine nucleotide biosynthetic process(GO:0019363)
0.0 1.0 GO:0006400 tRNA modification(GO:0006400)
0.0 2.2 GO:0050821 protein stabilization(GO:0050821)
0.0 1.6 GO:0042177 negative regulation of protein catabolic process(GO:0042177)
0.0 0.7 GO:0006911 phagocytosis, engulfment(GO:0006911)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 6.8 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
1.6 9.8 GO:0032133 chromosome passenger complex(GO:0032133)
1.3 6.6 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
1.0 7.3 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.9 4.7 GO:1990769 proximal neuron projection(GO:1990769)
0.8 3.3 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.8 4.1 GO:0070826 paraferritin complex(GO:0070826)
0.7 3.7 GO:0035189 Rb-E2F complex(GO:0035189)
0.6 3.8 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.6 5.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.5 12.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.4 4.9 GO:0005642 annulate lamellae(GO:0005642)
0.4 1.7 GO:0097450 astrocyte end-foot(GO:0097450)
0.4 2.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.4 3.4 GO:0070578 RISC-loading complex(GO:0070578)
0.3 3.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.3 2.3 GO:0030314 junctional membrane complex(GO:0030314)
0.2 1.7 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.2 0.9 GO:0097454 Schwann cell microvillus(GO:0097454)
0.2 10.9 GO:0045171 intercellular bridge(GO:0045171)
0.2 5.4 GO:0001891 phagocytic cup(GO:0001891)
0.2 0.9 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.2 3.9 GO:0034706 sodium channel complex(GO:0034706)
0.2 2.3 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 0.6 GO:0036449 cortical microtubule cytoskeleton(GO:0030981) microtubule minus-end(GO:0036449)
0.1 0.5 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 5.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 1.6 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 1.1 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 1.8 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.1 2.8 GO:0042588 zymogen granule(GO:0042588)
0.1 9.6 GO:0005882 intermediate filament(GO:0005882)
0.1 4.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 1.0 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 1.3 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 1.0 GO:0042581 specific granule(GO:0042581)
0.1 1.1 GO:0044232 organelle membrane contact site(GO:0044232)
0.1 0.6 GO:0031415 NatA complex(GO:0031415)
0.1 1.8 GO:0005859 muscle myosin complex(GO:0005859) myosin filament(GO:0032982)
0.1 5.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 13.0 GO:0000793 condensed chromosome(GO:0000793)
0.1 1.8 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 7.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 1.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.0 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.0 1.5 GO:0001533 cornified envelope(GO:0001533)
0.0 0.5 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 3.1 GO:0005901 caveola(GO:0005901)
0.0 1.7 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 1.2 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 3.2 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 4.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 3.7 GO:0030139 endocytic vesicle(GO:0030139)
0.0 35.1 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 5.3 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.7 GO:0005921 gap junction(GO:0005921)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 1.8 GO:0055037 recycling endosome(GO:0055037)
0.0 4.9 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 1.6 GO:0030863 cortical cytoskeleton(GO:0030863)
0.0 0.8 GO:0005643 nuclear pore(GO:0005643)
0.0 0.8 GO:0000776 kinetochore(GO:0000776)
0.0 5.6 GO:0005813 centrosome(GO:0005813)
0.0 10.7 GO:0030054 cell junction(GO:0030054)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 13.8 GO:0004349 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
3.3 26.4 GO:0050786 RAGE receptor binding(GO:0050786)
2.4 7.2 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
1.7 6.8 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
1.6 11.3 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
1.4 16.6 GO:0036374 glutathione hydrolase activity(GO:0036374)
1.3 6.6 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
1.1 3.3 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.9 13.9 GO:0050693 LBD domain binding(GO:0050693)
0.8 4.1 GO:0015094 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.8 2.4 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.8 12.6 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.8 2.3 GO:0098809 nitrite reductase activity(GO:0098809)
0.7 11.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.6 3.6 GO:0004359 glutaminase activity(GO:0004359)
0.5 9.8 GO:0035174 histone serine kinase activity(GO:0035174)
0.5 1.5 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.5 2.5 GO:0016726 aldehyde oxidase activity(GO:0004031) xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.5 4.9 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.5 4.2 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.5 5.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.4 2.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.3 3.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.3 1.3 GO:2001069 glycogen binding(GO:2001069)
0.3 1.3 GO:0046870 cadmium ion binding(GO:0046870)
0.3 2.8 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.3 2.4 GO:1990380 Lys63-specific deubiquitinase activity(GO:0061578) Lys48-specific deubiquitinase activity(GO:1990380)
0.3 4.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.3 1.4 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.3 1.0 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 2.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 1.9 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2 1.8 GO:0001849 complement component C1q binding(GO:0001849)
0.2 2.9 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.2 0.9 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.2 2.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2 12.5 GO:0015485 cholesterol binding(GO:0015485)
0.2 12.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 0.9 GO:0050816 phosphothreonine binding(GO:0050816)
0.2 1.9 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.2 5.7 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.2 0.9 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 3.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 0.6 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.5 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 2.3 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.1 1.2 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 0.4 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 2.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.9 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 1.8 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 10.8 GO:0005179 hormone activity(GO:0005179)
0.1 0.3 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.1 0.5 GO:0048039 ubiquinone binding(GO:0048039)
0.1 10.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 2.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 0.6 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 2.3 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 2.4 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.1 1.5 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 0.3 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 1.8 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.3 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 1.1 GO:0070064 proline-rich region binding(GO:0070064)
0.0 2.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 2.1 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.8 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.6 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 1.1 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 1.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0004568 chitinase activity(GO:0004568)
0.0 1.7 GO:0043022 ribosome binding(GO:0043022)
0.0 0.2 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 5.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.6 GO:0031005 filamin binding(GO:0031005)
0.0 1.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.0 GO:0005549 odorant binding(GO:0005549)
0.0 2.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 6.0 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 2.3 GO:0020037 heme binding(GO:0020037)
0.0 2.4 GO:0044325 ion channel binding(GO:0044325)
0.0 1.8 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 0.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 2.5 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 3.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.8 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.9 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.8 GO:0030507 spectrin binding(GO:0030507)
0.0 0.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 8.4 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 1.1 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.6 GO:0019894 kinesin binding(GO:0019894)
0.0 0.6 GO:0035064 methylated histone binding(GO:0035064)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 21.4 PID AURORA A PATHWAY Aurora A signaling
0.5 3.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.4 11.3 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.3 4.9 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.3 10.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 10.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.2 10.8 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.2 2.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2 12.0 PID E2F PATHWAY E2F transcription factor network
0.1 15.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 9.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 1.3 PID IL27 PATHWAY IL27-mediated signaling events
0.1 3.3 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 4.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 2.8 PID ENDOTHELIN PATHWAY Endothelins
0.1 3.8 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.9 PID MYC PATHWAY C-MYC pathway
0.0 2.0 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.5 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.7 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.0 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.6 PID CASPASE PATHWAY Caspase cascade in apoptosis

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 7.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
1.0 16.0 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.9 15.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.7 8.0 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.6 8.0 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.5 12.8 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.4 16.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.4 9.8 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.3 12.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 2.8 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.1 3.3 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 9.8 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1 4.8 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 1.6 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 1.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 1.6 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.1 3.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 9.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 2.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 0.6 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1 1.7 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.1 2.9 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 0.4 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 1.7 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.1 2.4 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 5.3 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 8.5 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 3.1 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 2.9 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.0 3.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 1.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 13.8 REACTOME HEMOSTASIS Genes involved in Hemostasis
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.8 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 4.6 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates