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GSE58827: Dynamics of the Mouse Liver

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Results for Tcf7_Tcf7l2

Z-value: 1.24

Motif logo

Transcription factors associated with Tcf7_Tcf7l2

Gene Symbol Gene ID Gene Info
ENSMUSG00000000782.9 transcription factor 7, T cell specific
ENSMUSG00000024985.12 transcription factor 7 like 2, T cell specific, HMG box

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tcf7mm10_v2_chr11_-_52282564_522825790.774.3e-08Click!
Tcf7l2mm10_v2_chr19_+_55894508_558945340.554.8e-04Click!

Activity profile of Tcf7_Tcf7l2 motif

Sorted Z-values of Tcf7_Tcf7l2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_145805862 9.49 ENSMUST00000067479.5
cytochrome P450, family 3, subfamily a, polypeptide 44
chr14_-_56062307 8.01 ENSMUST00000043249.8
mast cell protease 4
chr5_-_145469723 6.58 ENSMUST00000031633.4
cytochrome P450, family 3, subfamily a, polypeptide 16
chr6_-_40999479 5.33 ENSMUST00000166306.1
predicted gene 2663
chr7_+_13733502 4.65 ENSMUST00000086148.6
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2
chr3_-_107239707 4.49 ENSMUST00000049852.8
prokineticin 1
chr17_+_25366550 4.25 ENSMUST00000069616.7
tryptase beta 2
chr7_-_13989588 3.83 ENSMUST00000165167.1
ENSMUST00000108520.2
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 4
chr8_-_111691002 3.71 ENSMUST00000034435.5
chymotrypsinogen B1
chr11_+_108920800 3.65 ENSMUST00000140821.1
axin2
chr5_-_145584723 3.51 ENSMUST00000075837.6
cytochrome P450, family 3, subfamily a, polypeptide 41B
chr7_+_13623967 3.19 ENSMUST00000108525.2
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 5
chr18_+_21072329 2.94 ENSMUST00000082235.4
meprin 1 beta
chr7_-_142576492 2.94 ENSMUST00000140716.1
H19 fetal liver mRNA
chr19_+_38132767 2.69 ENSMUST00000025956.5
ENSMUST00000112329.1
phosphodiesterase 6C, cGMP specific, cone, alpha prime
chr8_+_71597648 2.66 ENSMUST00000143662.1
family with sequence similarity 129, member C
chr6_-_69400097 2.50 ENSMUST00000177795.1
immunoglobulin kappa variable 4-62
chr9_+_46240696 2.48 ENSMUST00000034585.6
apolipoprotein A-IV
chr7_-_142657466 2.43 ENSMUST00000097936.2
ENSMUST00000000033.5
insulin-like growth factor 2
chr6_+_129591782 2.33 ENSMUST00000112063.2
ENSMUST00000032268.7
ENSMUST00000119520.1
killer cell lectin-like receptor, subfamily D, member 1
chr6_+_115422040 2.28 ENSMUST00000000450.3
peroxisome proliferator activated receptor gamma
chr9_-_96719549 2.24 ENSMUST00000128269.1
zinc finger and BTB domain containing 38
chr11_-_99322943 2.12 ENSMUST00000038004.2
keratin 25
chr7_-_142656018 2.04 ENSMUST00000178921.1
insulin-like growth factor 2
chrX_+_6415736 2.00 ENSMUST00000143641.3
shroom family member 4
chr7_+_45216671 1.99 ENSMUST00000134420.1
TEA domain family member 2
chr2_+_96318014 1.88 ENSMUST00000135431.1
ENSMUST00000162807.2
leucine rich repeat containing 4C
chr1_+_88166004 1.88 ENSMUST00000097659.4
UDP glucuronosyltransferase 1 family, polypeptide A5
chr14_-_70323783 1.83 ENSMUST00000151011.1
solute carrier family 39 (zinc transporter), member 14
chr2_-_150255591 1.83 ENSMUST00000063463.5
predicted gene 21994
chr10_-_128960965 1.75 ENSMUST00000026398.3
methyltransferase like 7B
chr6_+_78405148 1.75 ENSMUST00000023906.2
regenerating islet-derived 2
chr7_-_31076656 1.72 ENSMUST00000167369.1
FXYD domain-containing ion transport regulator 3
chr16_-_45492962 1.71 ENSMUST00000114585.2
predicted gene 609
chr5_-_44102032 1.67 ENSMUST00000171543.1
prominin 1
chr6_-_69284319 1.66 ENSMUST00000103349.1
immunoglobulin kappa variable 4-69
chr8_+_21734490 1.65 ENSMUST00000080533.5
defensin, alpha, 24
chr19_+_39992424 1.64 ENSMUST00000049178.2
cytochrome P450, family 2. subfamily c, polypeptide 37
chr5_-_62765618 1.64 ENSMUST00000159470.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr6_+_40964760 1.59 ENSMUST00000076638.5
RIKEN cDNA 1810009J06 gene
chr13_+_65512678 1.56 ENSMUST00000081471.2
predicted gene 10139
chr10_-_127370535 1.54 ENSMUST00000026472.8
inhibin beta-C
chr19_+_18749983 1.53 ENSMUST00000040489.7
transient receptor potential cation channel, subfamily M, member 6
chr11_+_108921648 1.51 ENSMUST00000144511.1
axin2
chr17_+_8236031 1.48 ENSMUST00000164411.2
chemokine (C-C motif) receptor 6
chr14_+_63436394 1.48 ENSMUST00000121288.1
family with sequence similarity 167, member A
chr13_+_4434306 1.48 ENSMUST00000021630.8
aldo-keto reductase family 1, member C6
chr13_-_66851513 1.47 ENSMUST00000169322.1
predicted gene, 17404
chr10_-_13388830 1.44 ENSMUST00000079698.5
phosphatase and actin regulator 2
chr15_-_54278420 1.41 ENSMUST00000079772.3
tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
chr3_+_57425314 1.41 ENSMUST00000029377.7
transmembrane 4 superfamily member 4
chr4_+_44943727 1.37 ENSMUST00000154177.1
predicted gene 12678
chr15_+_9436028 1.35 ENSMUST00000042360.3
calcyphosine-like
chr2_-_62483637 1.35 ENSMUST00000136686.1
ENSMUST00000102733.3
glucagon
chr11_+_67277124 1.34 ENSMUST00000019625.5
myosin, heavy polypeptide 8, skeletal muscle, perinatal
chr3_-_96814518 1.34 ENSMUST00000047702.7
CD160 antigen
chr17_-_78684262 1.34 ENSMUST00000145480.1
striatin, calmodulin binding protein
chr2_-_164221605 1.32 ENSMUST00000018355.4
ENSMUST00000109376.2
WAP four-disulfide core domain 15B
chr8_+_109990430 1.31 ENSMUST00000001720.7
ENSMUST00000143741.1
tyrosine aminotransferase
chr12_-_41485751 1.29 ENSMUST00000043884.4
leucine rich repeat protein 3, neuronal
chr1_+_131638306 1.28 ENSMUST00000073350.6
cathepsin E
chr19_-_39886730 1.28 ENSMUST00000168838.1
cytochrome P450, family 2, subfamily c, polypeptide 69
chr6_-_69243445 1.26 ENSMUST00000101325.3
immunoglobulin kappa chain variable 4-71
chr9_-_96719404 1.21 ENSMUST00000140121.1
zinc finger and BTB domain containing 38
chr10_+_127849917 1.20 ENSMUST00000077530.2
retinol dehydrogenase 19
chr2_-_150179679 1.17 ENSMUST00000099418.2
predicted gene 10770
chr13_+_94083490 1.17 ENSMUST00000156071.1
lipoma HMGIC fusion partner-like 2
chr6_+_129045893 1.17 ENSMUST00000032257.7
killer cell lectin-like receptor subfamily B member 1F
chr4_-_134254076 1.15 ENSMUST00000060050.5
glycine/arginine rich protein 1
chr11_+_108920342 1.13 ENSMUST00000052915.7
axin2
chr4_+_141420757 1.12 ENSMUST00000102486.4
heat shock protein family, member 7 (cardiovascular)
chr10_-_13388753 1.11 ENSMUST00000105546.1
phosphatase and actin regulator 2
chr9_-_123862023 1.08 ENSMUST00000182350.1
ENSMUST00000078755.2
chemokine (C motif) receptor 1
chrX_-_150812932 1.06 ENSMUST00000131241.1
ENSMUST00000147152.1
ENSMUST00000143843.1
melanoma antigen, family D, 2
chr19_+_8591254 1.02 ENSMUST00000010251.3
ENSMUST00000170817.1
solute carrier family 22 (organic anion transporter), member 8
chr3_+_55242526 0.99 ENSMUST00000054237.7
ENSMUST00000167204.1
doublecortin-like kinase 1
chr8_-_95294074 0.98 ENSMUST00000184103.1
cyclic nucleotide gated channel beta 1
chr7_+_128062657 0.97 ENSMUST00000120355.1
ENSMUST00000106240.2
ENSMUST00000098015.3
integrin alpha M
chr14_+_45219993 0.96 ENSMUST00000146150.1
G protein-coupled receptor 137C
chr1_-_139560158 0.96 ENSMUST00000160423.1
ENSMUST00000023965.5
complement factor H-related 1
chr9_+_77921908 0.95 ENSMUST00000133757.1
ELOVL family member 5, elongation of long chain fatty acids (yeast)
chr13_+_54701457 0.95 ENSMUST00000037145.7
cadherin-related family member 2
chr9_+_75232013 0.94 ENSMUST00000036555.6
myosin VC
chr5_-_145879857 0.94 ENSMUST00000035918.7
cytochrome P450, family 3, subfamily a, polypeptide 11
chr5_-_87569023 0.92 ENSMUST00000113314.2
sulfotransferase family 1D, member 1
chr7_-_48558066 0.89 ENSMUST00000052730.1
MAS-related GPR, member B2
chr13_-_56548534 0.88 ENSMUST00000062806.4
leukocyte cell-derived chemotaxin 2
chr7_-_134225088 0.86 ENSMUST00000067680.4
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr10_-_115587739 0.86 ENSMUST00000020350.8
leucine rich repeat containing G protein coupled receptor 5
chr9_+_51280295 0.85 ENSMUST00000050829.1
RIKEN cDNA 2010007H06 gene
chr11_-_60036917 0.85 ENSMUST00000102692.3
phosphatidylethanolamine N-methyltransferase
chr12_+_24831583 0.83 ENSMUST00000110942.3
ENSMUST00000078902.6
membrane bound O-acyltransferase domain containing 2
chr14_-_45219364 0.83 ENSMUST00000022377.4
ENSMUST00000143609.1
ENSMUST00000139526.1
thioredoxin domain containing 16
chr6_-_87335758 0.81 ENSMUST00000042025.9
anthrax toxin receptor 1
chr10_-_22820126 0.80 ENSMUST00000049930.7
transcription factor 21
chr4_+_95967322 0.80 ENSMUST00000107083.1
hook homolog 1 (Drosophila)
chr5_+_99979061 0.79 ENSMUST00000046721.1
RIKEN cDNA 4930524J08 gene
chr17_-_47016956 0.78 ENSMUST00000165525.1
predicted gene 16494
chr14_+_101840501 0.78 ENSMUST00000159026.1
LIM domain only 7
chr16_-_44139630 0.75 ENSMUST00000137557.1
ENSMUST00000147025.1
ATPase, H+ transporting, lysosomal V1 subunit A
chrX_-_150812715 0.73 ENSMUST00000112697.3
melanoma antigen, family D, 2
chr15_+_102296256 0.72 ENSMUST00000064924.4
extra spindle poles-like 1 (S. cerevisiae)
chr13_-_66852017 0.72 ENSMUST00000059329.6
predicted gene, 17449
chr14_+_51114455 0.72 ENSMUST00000100645.3
epididymal protein 3B
chr10_+_21978643 0.72 ENSMUST00000142174.1
ENSMUST00000164659.1
serum/glucocorticoid regulated kinase 1
chr7_-_47528862 0.72 ENSMUST00000172559.1
MAS-related GPR, member A2B
chr1_+_88095054 0.72 ENSMUST00000150634.1
ENSMUST00000058237.7
UDP glucuronosyltransferase 1 family, polypeptide A7C
chr13_+_47122719 0.71 ENSMUST00000068891.4
ring finger protein 144B
chr1_+_88087802 0.71 ENSMUST00000113139.1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr13_-_41828418 0.70 ENSMUST00000137905.1
androgen dependent TFPI regulating protein
chr3_-_59130610 0.69 ENSMUST00000065220.6
ENSMUST00000091112.4
purinergic receptor P2Y, G-protein coupled, 14
chr3_+_55461758 0.68 ENSMUST00000070418.4
doublecortin-like kinase 1
chr7_-_45211877 0.68 ENSMUST00000033057.7
dickkopf-like 1
chr19_+_58670358 0.68 ENSMUST00000057270.7
pancreatic lipase
chr7_+_38183787 0.67 ENSMUST00000067854.8
ENSMUST00000177983.1
RIKEN cDNA 1600014C10 gene
chr8_-_86580664 0.67 ENSMUST00000131423.1
ENSMUST00000152438.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 12
chr4_-_19922599 0.67 ENSMUST00000029900.5
ATPase, H+ transporting, lysosomal V0 subunit D2
chr4_+_108479081 0.67 ENSMUST00000155068.1
zinc finger, CCHC domain containing 11
chr8_+_21665797 0.67 ENSMUST00000075268.4
predicted gene 15315
chr7_+_132859225 0.67 ENSMUST00000084497.5
ENSMUST00000181577.1
ENSMUST00000106161.1
family with sequence similarity 175, member B
chr10_+_115569986 0.66 ENSMUST00000173620.1
RIKEN cDNA A930009A15 gene
chr6_+_117168535 0.64 ENSMUST00000112866.1
ENSMUST00000112871.1
ENSMUST00000073043.4
chemokine (C-X-C motif) ligand 12
chr1_-_139781236 0.64 ENSMUST00000027612.8
ENSMUST00000111989.2
ENSMUST00000111986.2
predicted gene 4788
chr2_-_91931675 0.63 ENSMUST00000111309.1
midkine
chr1_+_172126750 0.63 ENSMUST00000075895.2
ENSMUST00000111252.3
peroxisomal biogenesis factor 19
chr1_+_88227005 0.62 ENSMUST00000061013.6
ENSMUST00000113130.1
maestro heat-like repeat family member 2A
chr11_+_108381164 0.62 ENSMUST00000146050.1
ENSMUST00000152958.1
apolipoprotein H
chr4_-_43429071 0.62 ENSMUST00000107929.3
ENSMUST00000107928.2
family with sequence similarity 166, member B
chr13_+_23870284 0.62 ENSMUST00000006785.7
solute carrier family 17 (sodium phosphate), member 1
chr2_-_91931696 0.62 ENSMUST00000090602.5
midkine
chr4_-_142239356 0.61 ENSMUST00000036476.3
kazrin, periplakin interacting protein
chr1_+_88070765 0.61 ENSMUST00000073772.4
UDP glucuronosyltransferase 1 family, polypeptide A9
chr2_+_157560078 0.61 ENSMUST00000153739.2
ENSMUST00000173595.1
ENSMUST00000109526.1
ENSMUST00000173839.1
ENSMUST00000173041.1
ENSMUST00000173793.1
ENSMUST00000172487.1
ENSMUST00000088484.5
neuronatin
chr13_-_62858364 0.60 ENSMUST00000021907.7
fructose bisphosphatase 2
chr1_-_133906973 0.60 ENSMUST00000126123.1
opticin
chr12_+_38783455 0.60 ENSMUST00000161980.1
ENSMUST00000160701.1
ets variant gene 1
chr8_+_21565368 0.59 ENSMUST00000084040.2
predicted gene 14850
chr15_-_78495059 0.59 ENSMUST00000089398.1
interleukin 2 receptor, beta chain
chr12_+_4133394 0.58 ENSMUST00000152065.1
ENSMUST00000127756.1
adenylate cyclase 3
chr1_-_75133866 0.58 ENSMUST00000027405.4
solute carrier family 23 (nucleobase transporters), member 3
chrY_+_90755657 0.58 ENSMUST00000167967.2
predicted gene, 21857
chr12_+_4133047 0.58 ENSMUST00000124505.1
adenylate cyclase 3
chr13_-_22219820 0.58 ENSMUST00000057516.1
vomeronasal 1 receptor 193
chr15_-_66286224 0.57 ENSMUST00000070256.7
potassium voltage-gated channel, subfamily Q, member 3
chr15_+_10981747 0.56 ENSMUST00000070877.5
alpha-methylacyl-CoA racemase
chr10_+_127000709 0.56 ENSMUST00000026500.5
ENSMUST00000142698.1
advillin
chr8_-_8639363 0.56 ENSMUST00000152698.1
ephrin B2
chr6_+_54267131 0.56 ENSMUST00000114402.2
chimerin (chimaerin) 2
chr13_-_107890059 0.56 ENSMUST00000105097.2
zinc finger SWIM-type containing 6
chr1_+_157506728 0.55 ENSMUST00000086130.2
SEC16 homolog B (S. cerevisiae)
chr2_+_70474923 0.54 ENSMUST00000100043.2
trans-acting transcription factor 5
chr1_+_157506777 0.54 ENSMUST00000027881.8
SEC16 homolog B (S. cerevisiae)
chr6_+_117559694 0.54 ENSMUST00000162741.1
ENSMUST00000008011.7
predicted gene 9946
chr1_-_168432270 0.54 ENSMUST00000072863.4
pre B cell leukemia homeobox 1
chr1_+_88055467 0.53 ENSMUST00000173325.1
UDP glycosyltransferase 1 family, polypeptide A10
chr3_-_15838643 0.53 ENSMUST00000148194.1
signal-regulatory protein beta 1C
chr5_-_105239533 0.52 ENSMUST00000065588.6
guanylate-binding protein 10
chr16_+_29210108 0.52 ENSMUST00000162747.1
HRAS-like suppressor
chr5_+_17574268 0.52 ENSMUST00000030568.7
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr5_+_86071734 0.52 ENSMUST00000031171.7
signal transducing adaptor family member 1
chr10_+_38965515 0.51 ENSMUST00000019992.5
laminin, alpha 4
chr14_+_54431597 0.51 ENSMUST00000089688.4
matrix metallopeptidase 14 (membrane-inserted)
chr3_+_118562129 0.50 ENSMUST00000039177.7
dihydropyrimidine dehydrogenase
chr4_+_121039385 0.50 ENSMUST00000030372.5
collagen, type IX, alpha 2
chr4_-_43429117 0.50 ENSMUST00000171134.2
ENSMUST00000052829.3
family with sequence similarity 166, member B
chr11_+_96929367 0.49 ENSMUST00000062172.5
proline rich 15-like
chr4_-_16013796 0.48 ENSMUST00000149891.1
oxidative stress induced growth inhibitor family member 2
chr18_+_37400845 0.48 ENSMUST00000057228.1
protocadherin beta 9
chr6_+_72629284 0.47 ENSMUST00000156497.1
predicted gene 15401
chr3_-_116712696 0.47 ENSMUST00000169530.1
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr10_+_69787431 0.46 ENSMUST00000183240.1
ankyrin 3, epithelial
chr6_+_86628174 0.46 ENSMUST00000043400.6
aspartic peptidase, retroviral-like 1
chr4_+_45848816 0.46 ENSMUST00000107782.1
ENSMUST00000030011.5
RIKEN cDNA 1300002K09 gene
chr14_+_56017964 0.46 ENSMUST00000022836.4
mast cell protease 1
chr18_+_44334062 0.46 ENSMUST00000025349.5
ENSMUST00000115498.1
myotilin
chr8_+_21297439 0.45 ENSMUST00000098892.4
defensin, alpha, 5
chr4_-_106727930 0.45 ENSMUST00000106770.1
ENSMUST00000145044.1
maestro heat-like repeat family member 7
chrX_+_169879596 0.45 ENSMUST00000112105.1
ENSMUST00000078947.5
midline 1
chr13_+_42301270 0.44 ENSMUST00000021796.7
endothelin 1
chr5_-_108795352 0.44 ENSMUST00000004943.1
transmembrane emp24 protein transport domain containing
chr7_+_128062635 0.44 ENSMUST00000064821.7
ENSMUST00000106242.3
integrin alpha M
chr8_-_107065632 0.44 ENSMUST00000034393.5
transmembrane emp24 protein transport domain containing 6
chr12_-_87299705 0.43 ENSMUST00000125733.1
isthmin 2 homolog (zebrafish)
chr4_+_32238713 0.43 ENSMUST00000108180.2
BTB and CNC homology 2
chr1_+_88055377 0.42 ENSMUST00000138182.1
ENSMUST00000113142.3
UDP glycosyltransferase 1 family, polypeptide A10
chr6_-_71322200 0.42 ENSMUST00000173297.1
ENSMUST00000114188.2
SET and MYND domain containing 1
chr7_-_3845050 0.41 ENSMUST00000108615.3
ENSMUST00000119469.1
paired-Ig-like receptor A2
chr14_+_53665912 0.40 ENSMUST00000181768.1
T cell receptor alpha variable 3-3
chr9_-_71896047 0.40 ENSMUST00000184448.1
transcription factor 12
chr9_-_98033181 0.40 ENSMUST00000035027.6
calsyntenin 2
chr7_+_140247316 0.39 ENSMUST00000164583.1
ENSMUST00000093984.2
RIKEN cDNA 5830411N06 gene
chr1_+_139454747 0.39 ENSMUST00000053364.8
ENSMUST00000097554.3
asp (abnormal spindle)-like, microcephaly associated (Drosophila)
chr17_-_40794063 0.39 ENSMUST00000131699.1
ENSMUST00000024724.7
ENSMUST00000144243.1
cysteine-rich secretory protein 2
chr2_-_35061431 0.38 ENSMUST00000028233.3
hemolytic complement
chr1_+_171840557 0.38 ENSMUST00000135386.1
CD84 antigen
chr11_-_110251736 0.38 ENSMUST00000044003.7
ATP-binding cassette, sub-family A (ABC1), member 6
chr4_+_136206365 0.37 ENSMUST00000047526.7
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr13_+_45389734 0.37 ENSMUST00000038275.9
myosin regulatory light chain interacting protein
chr10_+_89744988 0.37 ENSMUST00000020112.5
UHRF1 (ICBP90) binding protein 1-like
chr19_-_40073731 0.37 ENSMUST00000048959.3
cytochrome P450, family 2, subfamily c, polypeptide 54

Network of associatons between targets according to the STRING database.

First level regulatory network of Tcf7_Tcf7l2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.3 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.8 2.5 GO:0034443 negative regulation of lipoprotein oxidation(GO:0034443) multicellular organism lipid catabolic process(GO:0044240)
0.8 2.3 GO:2000229 pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229)
0.6 8.0 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.6 4.5 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.6 1.7 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.5 1.5 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.4 4.9 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.4 1.5 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.3 1.0 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.3 0.8 GO:0060435 bronchiole development(GO:0060435) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.3 1.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.2 1.7 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.2 0.7 GO:0032685 negative regulation of granulocyte macrophage colony-stimulating factor production(GO:0032685)
0.2 2.9 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.2 1.8 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.2 0.8 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.2 2.5 GO:0046549 retinal cone cell development(GO:0046549)
0.2 1.2 GO:0008355 olfactory learning(GO:0008355)
0.2 1.4 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.2 0.9 GO:1904970 brush border assembly(GO:1904970)
0.2 0.9 GO:0000103 sulfate assimilation(GO:0000103)
0.2 0.9 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.2 1.3 GO:0030421 defecation(GO:0030421)
0.2 0.7 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.2 0.9 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.2 0.2 GO:0007521 muscle cell fate determination(GO:0007521)
0.2 0.5 GO:0046104 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859) thymidine metabolic process(GO:0046104)
0.1 0.9 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.1 1.4 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.1 0.8 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.1 2.0 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.1 0.4 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 1.1 GO:0048207 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 1.0 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 0.6 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.1 0.2 GO:0018879 biphenyl metabolic process(GO:0018879)
0.1 3.4 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.3 GO:0034148 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573)
0.1 0.5 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.1 0.6 GO:0034197 blood coagulation, intrinsic pathway(GO:0007597) acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 1.5 GO:0016540 protein autoprocessing(GO:0016540)
0.1 0.5 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 1.0 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.6 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.1 1.3 GO:0030049 muscle filament sliding(GO:0030049)
0.1 0.9 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.7 GO:0001967 suckling behavior(GO:0001967)
0.1 0.4 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 0.7 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.4 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.1 0.2 GO:0002355 detection of tumor cell(GO:0002355)
0.1 2.1 GO:0045109 intermediate filament organization(GO:0045109)
0.1 0.6 GO:1903849 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.1 0.1 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.1 0.3 GO:1900368 regulation of RNA interference(GO:1900368)
0.1 0.6 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.1 0.2 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.1 1.2 GO:0032252 secretory granule localization(GO:0032252)
0.1 0.5 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.1 0.2 GO:0042977 regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)
0.1 2.0 GO:0048339 paraxial mesoderm development(GO:0048339)
0.1 2.9 GO:1901998 toxin transport(GO:1901998)
0.1 0.6 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.2 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.1 0.7 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.0 0.7 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.2 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.0 0.7 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.1 GO:0050883 regulation of sulfur amino acid metabolic process(GO:0031335) musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 0.5 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.2 GO:0003273 cell migration involved in endocardial cushion formation(GO:0003273) condensed mesenchymal cell proliferation(GO:0072137)
0.0 1.4 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.3 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.0 0.5 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.2 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0 0.2 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.4 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 1.7 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.3 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.3 GO:0015961 diadenosine polyphosphate catabolic process(GO:0015961)
0.0 0.5 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.2 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.0 0.2 GO:0051697 protein delipidation(GO:0051697)
0.0 0.5 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 5.0 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.1 GO:1901249 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
0.0 0.3 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 0.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 1.5 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 2.0 GO:0002228 natural killer cell mediated immunity(GO:0002228)
0.0 0.9 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.1 GO:1903334 positive regulation of protein folding(GO:1903334)
0.0 0.6 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 4.3 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.1 GO:0032329 serine transport(GO:0032329)
0.0 1.7 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.3 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.0 0.4 GO:0034391 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.0 1.1 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 1.6 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.4 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 2.8 GO:0007586 digestion(GO:0007586)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.7 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 1.4 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.2 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.2 GO:0051596 methylglyoxal metabolic process(GO:0009438) methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.5 GO:0030325 adrenal gland development(GO:0030325)
0.0 1.8 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.5 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.4 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.1 GO:1904784 NLRP1 inflammasome complex assembly(GO:1904784)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0034651 cortisol biosynthetic process(GO:0034651)
0.0 0.3 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.3 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.3 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.1 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.0 0.2 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.0 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.0 0.1 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
0.0 2.7 GO:0006275 regulation of DNA replication(GO:0006275)
0.0 0.2 GO:0019441 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218) kynurenine metabolic process(GO:0070189)
0.0 0.1 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.1 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.2 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.1 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.3 GO:0015884 folic acid transport(GO:0015884)
0.0 0.8 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.6 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.3 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.5 GO:0051693 actin filament capping(GO:0051693)
0.0 0.4 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.2 GO:0010529 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0 0.7 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 1.9 GO:0042742 defense response to bacterium(GO:0042742)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.3 1.7 GO:0071914 prominosome(GO:0071914)
0.2 0.9 GO:0097447 dendritic tree(GO:0097447)
0.2 1.5 GO:0097524 sperm plasma membrane(GO:0097524)
0.2 1.1 GO:0070695 FHF complex(GO:0070695)
0.1 3.1 GO:0042627 chylomicron(GO:0042627)
0.1 0.4 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 0.9 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 0.4 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 0.3 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074) nuclear RNA export factor complex(GO:0042272)
0.1 0.3 GO:0044307 dendritic branch(GO:0044307)
0.1 0.4 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.4 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.5 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.7 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 1.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.8 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.6 GO:0001739 sex chromatin(GO:0001739)
0.1 0.4 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.7 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 1.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.8 GO:0016460 myosin II complex(GO:0016460)
0.0 0.2 GO:1990032 parallel fiber(GO:1990032)
0.0 1.7 GO:0008305 integrin complex(GO:0008305)
0.0 18.6 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 1.3 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 2.2 GO:0005844 polysome(GO:0005844)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)
0.0 0.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 4.4 GO:0072562 blood microparticle(GO:0072562)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 1.4 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.1 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.5 GO:0005605 basal lamina(GO:0005605)
0.0 0.6 GO:0030057 desmosome(GO:0030057)
0.0 1.0 GO:0016235 aggresome(GO:0016235)
0.0 2.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.7 GO:0031526 brush border membrane(GO:0031526)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 7.2 GO:0030141 secretory granule(GO:0030141)
0.0 27.4 GO:0005615 extracellular space(GO:0005615)
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.3 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.1 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.0 0.2 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 1.9 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.2 GO:0016580 Sin3 complex(GO:0016580)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 20.5 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
1.0 7.0 GO:0004027 alcohol sulfotransferase activity(GO:0004027)
0.8 2.3 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.5 1.5 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.4 1.3 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.3 6.3 GO:0070411 I-SMAD binding(GO:0070411)
0.3 2.5 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.2 1.7 GO:0001851 complement component C3b binding(GO:0001851)
0.2 0.6 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.2 1.2 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.2 2.5 GO:0050544 arachidonic acid binding(GO:0050544)
0.2 0.9 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.2 0.5 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 1.5 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 0.8 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 3.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.7 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 5.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 3.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 0.6 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 4.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 1.4 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 23.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.4 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 3.4 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.1 1.0 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.1 0.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.7 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.4 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.3 GO:0070401 NADP+ binding(GO:0070401)
0.1 1.9 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 0.2 GO:0004461 lactose synthase activity(GO:0004461)
0.1 0.9 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 1.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.9 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.5 GO:0002054 nucleobase binding(GO:0002054)
0.1 0.3 GO:0047710 bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.1 3.8 GO:0008146 sulfotransferase activity(GO:0008146)
0.1 0.2 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.1 1.1 GO:0031005 filamin binding(GO:0031005)
0.1 1.7 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.1 0.8 GO:0043855 cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 8.6 GO:0008083 growth factor activity(GO:0008083)
0.1 0.9 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 0.3 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.2 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700)
0.1 0.5 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 0.2 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.1 1.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 3.3 GO:0042805 actinin binding(GO:0042805)
0.0 1.3 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.7 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.3 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.6 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.6 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.0 0.3 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.2 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.2 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.0 0.2 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.0 0.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.3 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 1.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 3.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.2 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.3 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.3 GO:0051870 methotrexate binding(GO:0051870)
0.0 1.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 1.0 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:1901611 phosphatidylglycerol binding(GO:1901611)
0.0 0.3 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.5 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 0.4 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.5 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.2 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 2.8 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 1.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185) serine-type exopeptidase activity(GO:0070008)
0.0 0.0 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 3.0 GO:0030246 carbohydrate binding(GO:0030246)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.5 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 3.0 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 6.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 2.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 2.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 1.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 1.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.8 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.2 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.3 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.6 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.5 PID FOXO PATHWAY FoxO family signaling
0.0 0.4 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.3 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.4 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 1.2 PID CMYB PATHWAY C-MYB transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.2 3.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 4.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 1.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 0.3 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.1 3.2 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 0.5 REACTOME DEFENSINS Genes involved in Defensins
0.1 1.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 1.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.1 4.0 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 1.0 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 0.7 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 1.9 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 1.0 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.9 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.8 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 2.5 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.5 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 4.6 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.9 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.3 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.1 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.2 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 1.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 2.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.7 REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.0 0.4 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.3 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules