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GSE58827: Dynamics of the Mouse Liver

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Results for Stat4_Stat3_Stat5b

Z-value: 0.90

Motif logo

Transcription factors associated with Stat4_Stat3_Stat5b

Gene Symbol Gene ID Gene Info
ENSMUSG00000062939.5 signal transducer and activator of transcription 4
ENSMUSG00000004040.10 signal transducer and activator of transcription 3
ENSMUSG00000020919.5 signal transducer and activator of transcription 5B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Stat5bmm10_v2_chr11_-_100822525_1008225760.547.4e-04Click!
Stat3mm10_v2_chr11_-_100939540_1009395660.401.6e-02Click!
Stat4mm10_v2_chr1_+_52008210_52008254-0.392.0e-02Click!

Activity profile of Stat4_Stat3_Stat5b motif

Sorted Z-values of Stat4_Stat3_Stat5b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_95417352 7.73 ENSMUST00000181781.1
RIKEN cDNA 5730420D15 gene
chr14_+_30886476 6.54 ENSMUST00000006703.6
ENSMUST00000078490.5
ENSMUST00000120269.2
inter alpha-trypsin inhibitor, heavy chain 4
chr14_+_30886521 6.52 ENSMUST00000168782.1
inter alpha-trypsin inhibitor, heavy chain 4
chr10_-_95417099 5.37 ENSMUST00000135822.1
suppressor of cytokine signaling 2
chr8_+_105269837 5.29 ENSMUST00000172525.1
ENSMUST00000174837.1
ENSMUST00000173859.1
heat shock transcription factor 4
chr10_-_95416850 5.09 ENSMUST00000020215.9
suppressor of cytokine signaling 2
chr7_+_107567445 4.33 ENSMUST00000120990.1
olfactomedin-like 1
chr9_+_107296843 4.02 ENSMUST00000167072.1
cytokine inducible SH2-containing protein
chr8_-_124569696 3.78 ENSMUST00000063278.6
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr11_+_70054334 3.53 ENSMUST00000018699.6
ENSMUST00000108585.2
asialoglycoprotein receptor 1
chr5_+_7960445 3.46 ENSMUST00000115421.1
STEAP family member 4
chr17_-_56121946 3.14 ENSMUST00000041357.7
leucine-rich alpha-2-glycoprotein 1
chr16_+_62854299 3.10 ENSMUST00000023629.8
protein S (alpha)
chr13_-_41847482 3.06 ENSMUST00000072012.3
androgen dependent TFPI regulating protein
chr13_-_41847626 3.01 ENSMUST00000121404.1
androgen dependent TFPI regulating protein
chr9_+_107296682 2.98 ENSMUST00000168260.1
cytokine inducible SH2-containing protein
chr11_-_83530505 2.84 ENSMUST00000035938.2
chemokine (C-C motif) ligand 5
chr9_-_45009590 2.79 ENSMUST00000102832.1
CD3 antigen, epsilon polypeptide
chr13_-_41847599 2.78 ENSMUST00000179758.1
androgen dependent TFPI regulating protein
chrX_-_139782353 2.70 ENSMUST00000101217.3
ripply1 homolog (zebrafish)
chrX_-_108664891 2.68 ENSMUST00000178160.1
predicted gene 379
chr15_-_5063741 2.62 ENSMUST00000110689.3
complement component 7
chr7_-_81706905 2.61 ENSMUST00000026922.7
homer homolog 2 (Drosophila)
chrX_+_59999436 2.60 ENSMUST00000033477.4
coagulation factor IX
chr18_-_3281036 2.60 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
cAMP responsive element modulator
chr15_+_10223974 2.53 ENSMUST00000128450.1
ENSMUST00000148257.1
ENSMUST00000128921.1
prolactin receptor
chr10_-_109010955 2.51 ENSMUST00000105276.1
ENSMUST00000064054.7
synaptotagmin I
chr6_+_41521782 2.50 ENSMUST00000070380.4
protease, serine, 2
chr7_-_30924169 2.47 ENSMUST00000074671.6
hepcidin antimicrobial peptide 2
chr10_-_127070254 2.27 ENSMUST00000060991.4
tetraspanin 31
chr11_+_49087022 2.19 ENSMUST00000046704.6
interferon gamma inducible protein 47
chr11_+_78499087 2.17 ENSMUST00000017488.4
vitronectin
chr3_+_19957088 2.15 ENSMUST00000108328.1
ceruloplasmin
chr4_+_148602527 2.13 ENSMUST00000105701.2
ENSMUST00000052060.6
mannan-binding lectin serine peptidase 2
chr15_-_37458523 2.09 ENSMUST00000116445.2
neurocalcin delta
chr15_-_60921270 2.05 ENSMUST00000096418.3
alpha-1-B glycoprotein
chr5_+_130448801 2.03 ENSMUST00000111288.2
calneuron 1
chr16_-_35871544 2.03 ENSMUST00000042665.8
poly (ADP-ribose) polymerase family, member 14
chr3_+_19957037 2.00 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
ceruloplasmin
chr7_+_26808880 1.90 ENSMUST00000040944.7
cytochrome P450, family 2, subfamily g, polypeptide 1
chr8_+_104926237 1.88 ENSMUST00000034355.4
ENSMUST00000109410.2
carboxylesterase 2E
chr3_+_19957240 1.82 ENSMUST00000108325.2
ceruloplasmin
chr1_+_171214013 1.77 ENSMUST00000111328.1
nuclear receptor subfamily 1, group I, member 3
chr19_+_38481057 1.75 ENSMUST00000182481.1
phospholipase C, epsilon 1
chr4_-_140617062 1.75 ENSMUST00000154979.1
Rho guanine nucleotide exchange factor (GEF) 10-like
chr1_-_169747634 1.73 ENSMUST00000027991.5
ENSMUST00000111357.1
regulator of G-protein signaling 4
chr4_-_108031938 1.73 ENSMUST00000106708.1
podocan
chr4_-_108032069 1.70 ENSMUST00000106709.2
podocan
chr19_+_4711153 1.66 ENSMUST00000008991.6
spectrin beta, non-erythrocytic 2
chr1_-_155812805 1.65 ENSMUST00000111764.2
quiescin Q6 sulfhydryl oxidase 1
chr9_+_124021965 1.64 ENSMUST00000039171.7
chemokine (C-C motif) receptor 3
chr12_-_103989950 1.64 ENSMUST00000120251.2
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
chr1_-_155812859 1.64 ENSMUST00000035325.8
quiescin Q6 sulfhydryl oxidase 1
chr9_-_105960642 1.63 ENSMUST00000165165.2
collagen, type VI, alpha 5
chr7_-_141276729 1.62 ENSMUST00000167263.1
ENSMUST00000080654.5
cadherin-related family member 5
chr7_+_28180272 1.57 ENSMUST00000173223.1
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr12_-_103989917 1.50 ENSMUST00000151709.2
ENSMUST00000176246.1
ENSMUST00000074693.7
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
chr14_-_55713482 1.49 ENSMUST00000168729.1
ENSMUST00000178034.1
transglutaminase 1, K polypeptide
chr11_+_82035569 1.47 ENSMUST00000000193.5
chemokine (C-C motif) ligand 2
chr9_-_71163224 1.47 ENSMUST00000074465.2
aquaporin 9
chr7_+_28180226 1.44 ENSMUST00000172467.1
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr6_+_121346618 1.42 ENSMUST00000032200.9
solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12
chr6_+_41354105 1.41 ENSMUST00000072103.5
trypsin 10
chr1_+_171213969 1.39 ENSMUST00000005820.4
ENSMUST00000075469.5
ENSMUST00000155126.1
nuclear receptor subfamily 1, group I, member 3
chr17_-_34187219 1.34 ENSMUST00000173831.1
proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
chr6_-_41314700 1.33 ENSMUST00000064324.5
trypsin 5
chr5_+_88886809 1.31 ENSMUST00000148750.1
solute carrier family 4 (anion exchanger), member 4
chr17_+_34187545 1.31 ENSMUST00000170086.1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr5_+_90561102 1.29 ENSMUST00000094615.4
RIKEN cDNA 5830473C10 gene
chr15_-_54919961 1.28 ENSMUST00000167541.2
ENSMUST00000041591.9
ENSMUST00000173516.1
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr15_-_54920115 1.26 ENSMUST00000171545.1
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr16_-_23988852 1.25 ENSMUST00000023151.5
B cell leukemia/lymphoma 6
chr17_+_43667389 1.24 ENSMUST00000170988.1
cytochrome P450, family 39, subfamily a, polypeptide 1
chr17_+_34187789 1.22 ENSMUST00000041633.8
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr11_-_48994172 1.19 ENSMUST00000146439.1
T cell specific GTPase 1
chr14_+_65970610 1.19 ENSMUST00000127387.1
clusterin
chr14_+_65970804 1.17 ENSMUST00000138191.1
clusterin
chr4_+_11704439 1.17 ENSMUST00000108304.2
GTP binding protein (gene overexpressed in skeletal muscle)
chr17_-_78985428 1.14 ENSMUST00000118991.1
protein kinase D3
chr8_-_110805863 1.12 ENSMUST00000150680.1
ENSMUST00000076846.4
interleukin 34
chr14_+_65971049 1.12 ENSMUST00000128539.1
clusterin
chr9_-_51328898 1.12 ENSMUST00000039959.4
RIKEN cDNA 1810046K07 gene
chr7_+_127800604 1.11 ENSMUST00000046863.5
ENSMUST00000106272.1
ENSMUST00000139068.1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr2_-_84775420 1.11 ENSMUST00000111641.1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr1_+_133363564 1.11 ENSMUST00000135222.2
ethanolamine kinase 2
chr1_-_170976112 1.09 ENSMUST00000027966.7
ENSMUST00000081103.5
ENSMUST00000159688.1
Fc receptor, IgG, low affinity IIb
chr2_-_84775388 1.09 ENSMUST00000023994.3
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr7_-_105600103 1.07 ENSMUST00000033185.8
hemopexin
chr6_+_34598500 1.06 ENSMUST00000079391.3
ENSMUST00000142512.1
caldesmon 1
chr15_+_102102926 1.06 ENSMUST00000169627.1
ENSMUST00000046144.9
tensin like C1 domain-containing phosphatase
chr9_-_107679592 1.06 ENSMUST00000010205.7
guanine nucleotide binding protein, alpha transducing 1
chr4_-_57916283 1.04 ENSMUST00000063816.5
RIKEN cDNA D630039A03 gene
chr14_+_65971164 1.03 ENSMUST00000144619.1
clusterin
chr6_+_138141569 1.02 ENSMUST00000118091.1
microsomal glutathione S-transferase 1
chr6_+_34598530 1.01 ENSMUST00000115027.1
ENSMUST00000115026.1
caldesmon 1
chr15_-_37459327 1.00 ENSMUST00000119730.1
ENSMUST00000120746.1
neurocalcin delta
chr14_-_56262233 0.99 ENSMUST00000015581.4
granzyme B
chr7_+_127800844 0.99 ENSMUST00000106271.1
ENSMUST00000138432.1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr3_+_142496924 0.97 ENSMUST00000090127.2
guanylate binding protein 5
chr4_-_49473905 0.97 ENSMUST00000135976.1
acyl-coenzyme A amino acid N-acyltransferase 1
chr4_-_116017854 0.96 ENSMUST00000049095.5
fatty acid amide hydrolase
chr9_+_21015960 0.96 ENSMUST00000086399.4
intercellular adhesion molecule 1
chr15_-_89170688 0.94 ENSMUST00000060808.9
plexin B2
chr16_+_38902305 0.91 ENSMUST00000023478.7
immunoglobulin superfamily, member 11
chr19_-_21652714 0.86 ENSMUST00000177577.1
RIKEN cDNA 1110059E24 gene
chr19_-_29047847 0.85 ENSMUST00000025696.4
adenylate kinase 3
chr11_-_82764303 0.85 ENSMUST00000021040.3
ENSMUST00000100722.4
chaperonin containing Tcp1, subunit 6b (zeta)
chr5_-_66151323 0.85 ENSMUST00000131838.1
RNA binding motif protein 47
chr2_-_101628958 0.85 ENSMUST00000111231.3
RIKEN cDNA B230118H07 gene
chr9_-_44526397 0.84 ENSMUST00000062215.7
chemokine (C-X-C motif) receptor 5
chr1_+_136624901 0.84 ENSMUST00000047734.8
ENSMUST00000112046.1
zinc finger protein 281
chr2_-_101628930 0.83 ENSMUST00000099682.2
RIKEN cDNA B230118H07 gene
chr3_+_89229046 0.83 ENSMUST00000041142.3
mucin 1, transmembrane
chr17_-_32420965 0.82 ENSMUST00000170392.1
peptidoglycan recognition protein 2
chr1_-_172895048 0.81 ENSMUST00000027824.5
serum amyloid P-component
chr8_+_13895816 0.80 ENSMUST00000084055.7
predicted gene 7676
chr12_+_88953399 0.80 ENSMUST00000057634.7
neurexin III
chr1_-_9298499 0.79 ENSMUST00000132064.1
syntrophin, gamma 1
chr14_-_55713088 0.78 ENSMUST00000002389.7
transglutaminase 1, K polypeptide
chr17_-_74047850 0.78 ENSMUST00000043458.7
steroid 5 alpha-reductase 2
chr9_-_106476104 0.78 ENSMUST00000156426.1
poly (ADP-ribose) polymerase family, member 3
chr8_+_94532990 0.77 ENSMUST00000048653.2
ENSMUST00000109537.1
copine II
chr3_+_63295815 0.77 ENSMUST00000029400.1
membrane metallo endopeptidase
chr11_-_60046477 0.77 ENSMUST00000000310.7
ENSMUST00000102693.2
ENSMUST00000148512.1
phosphatidylethanolamine N-methyltransferase
chr3_-_98753465 0.76 ENSMUST00000094050.4
ENSMUST00000090743.6
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3
chr2_-_168712853 0.76 ENSMUST00000123156.1
ENSMUST00000156555.1
ATPase, class II, type 9A
chr7_+_24134148 0.76 ENSMUST00000056549.7
zinc finger protein 235
chr7_-_105399991 0.74 ENSMUST00000118726.1
ENSMUST00000074686.7
ENSMUST00000122327.1
ENSMUST00000179474.1
ENSMUST00000048079.6
family with sequence similarity 160, member A2
chr16_+_90738324 0.74 ENSMUST00000038197.2
melanocortin 2 receptor accessory protein
chr12_-_45074112 0.74 ENSMUST00000120531.1
ENSMUST00000143376.1
syntaxin binding protein 6 (amisyn)
chr8_+_105326354 0.73 ENSMUST00000015000.5
ENSMUST00000098453.2
transmembrane protein 208
chr10_-_95415283 0.73 ENSMUST00000119917.1
suppressor of cytokine signaling 2
chrX_+_57212110 0.73 ENSMUST00000033466.1
CD40 ligand
chr10_+_13966268 0.73 ENSMUST00000015645.4
human immunodeficiency virus type I enhancer binding protein 2
chr6_-_124911636 0.72 ENSMUST00000032217.1
lymphocyte-activation gene 3
chr7_-_30944017 0.72 ENSMUST00000062620.7
hepcidin antimicrobial peptide
chr3_+_122895072 0.71 ENSMUST00000023820.5
fatty acid binding protein 2, intestinal
chr16_-_30267524 0.70 ENSMUST00000064856.7
carboxypeptidase N, polypeptide 2
chr7_+_24270420 0.70 ENSMUST00000108438.3
zinc finger protein 93
chr2_-_77170534 0.70 ENSMUST00000111833.2
coiled-coil domain containing 141
chr17_+_35470083 0.69 ENSMUST00000174525.1
ENSMUST00000068291.6
histocompatibility 2, Q region locus 10
chr7_-_24208093 0.69 ENSMUST00000086006.5
zinc finger protein 111
chr18_-_33463615 0.69 ENSMUST00000051087.8
neuronal regeneration related protein
chr1_-_171240055 0.69 ENSMUST00000131286.1
NADH dehydrogenase (ubiquinone) Fe-S protein 2
chr11_+_58215028 0.68 ENSMUST00000108836.1
immunity-related GTPase family M member 2
chr6_+_108660772 0.68 ENSMUST00000163617.1
basic helix-loop-helix family, member e40
chr2_-_120314141 0.66 ENSMUST00000054651.7
phospholipase A2, group IVF
chr15_+_100304782 0.66 ENSMUST00000067752.3
methyltransferase like 7A1
chr19_-_4477447 0.65 ENSMUST00000059295.3
synaptotagmin XII
chr13_+_112464070 0.65 ENSMUST00000183663.1
ENSMUST00000184311.1
ENSMUST00000183886.1
interleukin 6 signal transducer
chr3_+_83007850 0.64 ENSMUST00000048486.7
fibrinogen gamma chain
chr6_-_18030435 0.64 ENSMUST00000010941.2
wingless-related MMTV integration site 2
chr11_-_21572193 0.64 ENSMUST00000102874.4
malate dehydrogenase 1, NAD (soluble)
chr19_-_58455161 0.63 ENSMUST00000135730.1
ENSMUST00000152507.1
glial cell line derived neurotrophic factor family receptor alpha 1
chr15_+_89076124 0.63 ENSMUST00000165690.1
TraB domain containing
chr11_-_113710017 0.62 ENSMUST00000018871.1
cleavage and polyadenylation specific factor 4-like
chr1_+_71652837 0.62 ENSMUST00000097699.2
apolipoprotein L 7d
chr7_+_102210335 0.62 ENSMUST00000140631.1
ENSMUST00000120879.1
ENSMUST00000146996.1
post-GPI attachment to proteins 2
chr11_+_120530688 0.61 ENSMUST00000026119.7
glucagon receptor
chr11_+_53770014 0.61 ENSMUST00000108920.2
ENSMUST00000140866.1
ENSMUST00000108922.1
interferon regulatory factor 1
chr11_-_69695802 0.61 ENSMUST00000108649.1
ENSMUST00000174159.1
ENSMUST00000181810.1
cDNA sequence BC096441
tumor necrosis factor (ligand) superfamily, member 12
chr17_-_28350747 0.61 ENSMUST00000080572.7
ENSMUST00000156862.1
TEA domain family member 3
chr11_-_49113757 0.60 ENSMUST00000060398.1
olfactory receptor 1396
chr11_-_106579111 0.59 ENSMUST00000103070.2
testis expressed gene 2
chr6_-_122282810 0.59 ENSMUST00000032207.8
killer cell lectin-like receptor subfamily G, member 1
chr11_-_53430417 0.59 ENSMUST00000109019.1
ubiquinol-cytochrome c reductase, complex III subunit VII
chr15_+_100353149 0.59 ENSMUST00000075675.5
ENSMUST00000088142.5
ENSMUST00000176287.1
cDNA sequence AB099516
methyltransferase like 7A2
chr9_-_103230415 0.59 ENSMUST00000035158.9
transferrin
chr1_+_164796723 0.59 ENSMUST00000027861.4
dermatopontin
chr10_-_54075702 0.58 ENSMUST00000105470.1
mannosidase 1, alpha
chr17_+_35126316 0.58 ENSMUST00000061859.6
DNA segment, Chr 17, human D6S53E
chr16_-_24393588 0.58 ENSMUST00000181640.1
RIKEN cDNA 1110054M08 gene
chr4_-_108118528 0.58 ENSMUST00000030340.8
sterol carrier protein 2, liver
chr5_-_66150898 0.57 ENSMUST00000113725.1
ENSMUST00000094757.2
RNA binding motif protein 47
chr13_-_17694729 0.57 ENSMUST00000068545.4
RIKEN cDNA 5033411D12 gene
chr11_-_69695753 0.57 ENSMUST00000180946.1
tumor necrosis factor (ligand) superfamily, member 12
chr11_-_51857624 0.57 ENSMUST00000020655.7
ENSMUST00000109090.1
PHD finger protein 15
chr2_+_101886249 0.57 ENSMUST00000028584.7
COMM domain containing 9
chr9_+_54286479 0.57 ENSMUST00000056740.5
gliomedin
chr8_+_107150621 0.57 ENSMUST00000034400.3
cytochrome b5 type B
chr7_-_127051948 0.57 ENSMUST00000051122.5
zymogen granule protein 16
chr7_-_99182681 0.57 ENSMUST00000033001.4
diacylglycerol O-acyltransferase 2
chr9_+_20868628 0.57 ENSMUST00000043911.7
RIKEN cDNA A230050P20 gene
chr11_-_69695521 0.56 ENSMUST00000181261.1
tumor necrosis factor (ligand) superfamily, member 12
chr5_-_103977360 0.56 ENSMUST00000048118.8
hydroxysteroid (17-beta) dehydrogenase 13
chr10_+_18235030 0.56 ENSMUST00000181897.1
predicted gene 10827
chr5_-_103977326 0.56 ENSMUST00000120320.1
hydroxysteroid (17-beta) dehydrogenase 13
chr17_+_56628118 0.56 ENSMUST00000112979.2
catsper channel auxiliary subunit delta
chr7_+_38183787 0.56 ENSMUST00000067854.8
ENSMUST00000177983.1
RIKEN cDNA 1600014C10 gene
chr10_-_54075730 0.56 ENSMUST00000105469.1
ENSMUST00000003843.8
mannosidase 1, alpha
chr14_+_27622433 0.56 ENSMUST00000090302.5
ELKS/RAB6-interacting/CAST family member 2
chr7_-_78577771 0.55 ENSMUST00000039438.7
neurotrophic tyrosine kinase, receptor, type 3
chr7_+_28179469 0.55 ENSMUST00000085901.6
ENSMUST00000172761.1
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr12_+_28675220 0.55 ENSMUST00000020957.6
acireductone dioxygenase 1
chr7_+_30095150 0.55 ENSMUST00000130526.1
ENSMUST00000108200.1
zinc finger protein 260
chr4_+_134396320 0.55 ENSMUST00000105869.2
platelet-activating factor acetylhydrolase 2
chr3_-_85741389 0.55 ENSMUST00000094148.4
family with sequence similarity 160, member A1
chr5_+_35041539 0.55 ENSMUST00000030985.6
hepatocyte growth factor activator
chr5_-_103977404 0.54 ENSMUST00000112803.2
hydroxysteroid (17-beta) dehydrogenase 13
chr8_+_127447669 0.54 ENSMUST00000159511.1
par-3 (partitioning defective 3) homolog (C. elegans)

Network of associatons between targets according to the STRING database.

First level regulatory network of Stat4_Stat3_Stat5b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0002019 regulation of renal output by angiotensin(GO:0002019) regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331) L-lysine transport(GO:1902022)
0.8 3.2 GO:0034760 negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760)
0.8 0.8 GO:0046449 creatinine metabolic process(GO:0046449)
0.8 4.5 GO:1902847 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.7 2.2 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.7 2.8 GO:2000503 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) positive regulation of natural killer cell chemotaxis(GO:2000503)
0.6 2.6 GO:0002434 immune complex clearance(GO:0002434)
0.6 1.2 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.6 2.8 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.5 2.0 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.5 2.5 GO:0046967 cytosol to ER transport(GO:0046967)
0.5 2.8 GO:0038161 prolactin signaling pathway(GO:0038161)
0.5 11.6 GO:0060396 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.4 1.2 GO:0030573 bile acid catabolic process(GO:0030573)
0.4 1.1 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.4 1.5 GO:0015851 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.4 2.5 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.4 1.4 GO:0009992 cellular water homeostasis(GO:0009992)
0.3 3.5 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.3 13.0 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.3 1.6 GO:1904970 brush border assembly(GO:1904970)
0.3 2.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.3 2.1 GO:0035754 B cell chemotaxis(GO:0035754)
0.3 2.7 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.3 1.2 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.3 0.8 GO:0052203 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.3 2.9 GO:0005513 detection of calcium ion(GO:0005513)
0.3 0.8 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.3 1.0 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.2 0.7 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.2 6.0 GO:0006825 copper ion transport(GO:0006825)
0.2 1.6 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.2 5.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.2 2.4 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.2 0.6 GO:0070104 negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.2 0.6 GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.2 1.1 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342)
0.2 1.0 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.2 2.2 GO:0097421 liver regeneration(GO:0097421)
0.2 1.0 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.2 0.5 GO:2000314 negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.2 0.7 GO:0006624 vacuolar protein processing(GO:0006624)
0.2 2.7 GO:0031000 response to caffeine(GO:0031000)
0.2 0.9 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.2 0.3 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.2 4.0 GO:0042730 fibrinolysis(GO:0042730)
0.2 1.0 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.2 0.5 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.2 1.6 GO:0002551 mast cell chemotaxis(GO:0002551) mast cell migration(GO:0097531)
0.2 1.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.2 0.8 GO:0032824 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253) negative regulation of natural killer cell differentiation(GO:0032824) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.2 0.5 GO:0015755 fructose transport(GO:0015755) cellular response to fructose stimulus(GO:0071332)
0.2 0.9 GO:0033762 response to glucagon(GO:0033762)
0.2 2.6 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.2 0.3 GO:0071724 response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.2 0.6 GO:0060416 response to growth hormone(GO:0060416)
0.2 0.9 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.1 1.5 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.6 GO:0032385 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.1 0.9 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 5.1 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 0.6 GO:0048691 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.1 0.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 0.6 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.1 2.6 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 1.9 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 0.4 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.1 1.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 1.0 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.1 0.7 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.1 0.3 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.7 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.1 3.4 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.1 0.3 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.1 0.5 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.3 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.4 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.1 0.7 GO:0030242 pexophagy(GO:0030242)
0.1 0.4 GO:1903027 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.1 0.2 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.1 0.5 GO:0071493 cellular response to UV-B(GO:0071493)
0.1 0.1 GO:1904526 regulation of microtubule binding(GO:1904526)
0.1 1.0 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.1 0.4 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.3 GO:0021837 motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) positive regulation of mitotic cell cycle DNA replication(GO:1903465)
0.1 0.6 GO:0006108 malate metabolic process(GO:0006108)
0.1 0.3 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.5 GO:0003383 apical constriction(GO:0003383)
0.1 0.4 GO:0030091 protein repair(GO:0030091)
0.1 0.4 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.5 GO:0061056 sclerotome development(GO:0061056)
0.1 0.8 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 1.8 GO:0006491 N-glycan processing(GO:0006491)
0.1 3.1 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 3.5 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.1 0.8 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 0.6 GO:0021539 subthalamus development(GO:0021539)
0.1 0.3 GO:0061144 alveolar secondary septum development(GO:0061144)
0.1 0.6 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.1 0.2 GO:0003257 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257)
0.1 0.2 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.1 0.4 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.1 0.2 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.5 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 0.3 GO:0000436 carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436) carbon catabolite activation of transcription(GO:0045991)
0.1 0.5 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.2 GO:0001788 antibody-dependent cellular cytotoxicity(GO:0001788)
0.1 1.0 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 0.2 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.1 1.7 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.3 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.4 GO:0090383 phagosome acidification(GO:0090383)
0.1 0.2 GO:0035627 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.1 0.6 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.8 GO:0042448 progesterone metabolic process(GO:0042448) testosterone biosynthetic process(GO:0061370)
0.1 3.6 GO:0060612 adipose tissue development(GO:0060612)
0.1 0.2 GO:1990859 cellular response to endothelin(GO:1990859)
0.1 0.3 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 0.2 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.3 GO:2001182 regulation of interleukin-12 secretion(GO:2001182)
0.1 0.3 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.1 0.3 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1 0.2 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.1 0.7 GO:0071236 cellular response to antibiotic(GO:0071236)
0.1 0.8 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.2 GO:0032242 positive regulation of necrotic cell death(GO:0010940) regulation of nucleoside transport(GO:0032242)
0.1 1.9 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.2 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.1 0.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 1.4 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.1 0.4 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 0.3 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.1 0.6 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.5 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.6 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0 0.4 GO:0051546 keratinocyte migration(GO:0051546)
0.0 0.3 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.2 GO:0021666 rhombomere formation(GO:0021594) rhombomere 3 formation(GO:0021660) rhombomere 5 morphogenesis(GO:0021664) rhombomere 5 formation(GO:0021666)
0.0 1.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.2 GO:0032627 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) positive regulation of interleukin-23 production(GO:0032747)
0.0 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.0 0.4 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.1 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.0 0.2 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.3 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.4 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 1.1 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.3 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.1 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.2 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.0 GO:2000793 cell proliferation involved in heart valve development(GO:2000793)
0.0 0.2 GO:0070164 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163) negative regulation of adiponectin secretion(GO:0070164)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.8 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.5 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.4 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.0 2.8 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:1900157 regulation of bone mineralization involved in bone maturation(GO:1900157)
0.0 0.4 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.8 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.3 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.0 1.4 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 1.4 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.3 GO:0002478 antigen processing and presentation of exogenous peptide antigen(GO:0002478)
0.0 0.3 GO:2000535 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.2 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 2.0 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.3 GO:0070200 establishment of protein localization to telomere(GO:0070200)
0.0 0.1 GO:0060995 pro-T cell differentiation(GO:0002572) cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.0 1.5 GO:0019882 antigen processing and presentation(GO:0019882)
0.0 0.1 GO:0045006 DNA deamination(GO:0045006)
0.0 0.2 GO:0003219 cardiac right ventricle formation(GO:0003219) cell proliferation involved in outflow tract morphogenesis(GO:0061325)
0.0 0.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.2 GO:0072530 purine-containing compound transmembrane transport(GO:0072530)
0.0 0.7 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.1 GO:1903011 negative regulation of bone development(GO:1903011) negative regulation of osteoclast development(GO:2001205)
0.0 3.2 GO:0007586 digestion(GO:0007586)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685) termination of signal transduction(GO:0023021)
0.0 0.5 GO:0030502 negative regulation of bone mineralization(GO:0030502) negative regulation of biomineral tissue development(GO:0070168)
0.0 2.9 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.5 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.3 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.2 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 1.1 GO:0021799 cerebral cortex radially oriented cell migration(GO:0021799)
0.0 1.1 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:0032899 regulation of neurotrophin production(GO:0032899) positive regulation of neurotrophin production(GO:0032901)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.5 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.3 GO:0070269 pyroptosis(GO:0070269)
0.0 0.2 GO:0097647 basement membrane assembly(GO:0070831) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.3 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.7 GO:0070266 necroptotic process(GO:0070266)
0.0 1.4 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.3 GO:0006884 cell volume homeostasis(GO:0006884)
0.0 0.2 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.6 GO:0048240 sperm capacitation(GO:0048240)
0.0 1.8 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.0 0.6 GO:0034340 response to type I interferon(GO:0034340)
0.0 0.5 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.0 2.0 GO:0032092 positive regulation of protein binding(GO:0032092)
0.0 0.9 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.3 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.6 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.1 GO:2000321 negative regulation of interleukin-1 beta secretion(GO:0050713) positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.0 0.3 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.3 GO:0006662 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.1 GO:0015791 polyol transport(GO:0015791)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.0 0.1 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.6 GO:0042775 mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.0 3.0 GO:0031668 cellular response to extracellular stimulus(GO:0031668)
0.0 0.1 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.1 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.1 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.5 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.5 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 2.0 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.0 0.1 GO:0033561 regulation of water loss via skin(GO:0033561) establishment of skin barrier(GO:0061436)
0.0 0.0 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 2.6 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.0 0.1 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.2 GO:0001702 gastrulation with mouth forming second(GO:0001702)
0.0 0.1 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.4 GO:0006458 'de novo' protein folding(GO:0006458)
0.0 0.2 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.8 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0044299 C-fiber(GO:0044299)
0.4 2.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.4 3.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.3 4.5 GO:0097418 neurofibrillary tangle(GO:0097418)
0.3 2.5 GO:0042825 TAP complex(GO:0042825)
0.3 1.3 GO:1990111 spermatoproteasome complex(GO:1990111)
0.3 2.1 GO:0030478 actin cap(GO:0030478)
0.2 2.6 GO:0005579 membrane attack complex(GO:0005579)
0.2 1.7 GO:0008091 spectrin(GO:0008091)
0.2 35.9 GO:0072562 blood microparticle(GO:0072562)
0.2 0.6 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.2 1.0 GO:0044194 cytolytic granule(GO:0044194)
0.2 0.8 GO:1902636 kinociliary basal body(GO:1902636)
0.2 0.5 GO:0070557 PCNA-p21 complex(GO:0070557)
0.2 1.6 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 2.5 GO:0031045 dense core granule(GO:0031045)
0.1 0.4 GO:0036019 endolysosome(GO:0036019)
0.1 1.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 2.5 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.7 GO:0070695 FHF complex(GO:0070695)
0.1 0.9 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 0.2 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 0.4 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.9 GO:0005767 secondary lysosome(GO:0005767) autolysosome(GO:0044754)
0.1 0.6 GO:0036128 CatSper complex(GO:0036128)
0.1 3.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 0.5 GO:0033269 internode region of axon(GO:0033269)
0.1 0.3 GO:0070876 SOSS complex(GO:0070876)
0.1 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.2 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.1 2.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.3 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.1 0.4 GO:0000322 storage vacuole(GO:0000322)
0.1 0.4 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 0.3 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.4 GO:0000137 Golgi cis cisterna(GO:0000137) Golgi trans cisterna(GO:0000138)
0.1 0.7 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.1 0.7 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.3 GO:0031673 H zone(GO:0031673)
0.0 0.7 GO:0045179 apical cortex(GO:0045179)
0.0 0.4 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.6 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 1.0 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.5 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 1.2 GO:0051233 spindle midzone(GO:0051233)
0.0 1.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.2 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 2.8 GO:0005811 lipid particle(GO:0005811)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.8 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 1.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.5 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.2 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.2 GO:0097342 death-inducing signaling complex(GO:0031264) ripoptosome(GO:0097342)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.4 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 1.1 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 1.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 1.3 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.4 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.1 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.4 GO:0030904 retromer complex(GO:0030904)
0.0 1.8 GO:0055037 recycling endosome(GO:0055037)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.6 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.3 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.2 GO:0042599 lamellar body(GO:0042599)
0.0 0.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 11.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.9 2.8 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.8 3.3 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.7 2.6 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.6 2.5 GO:0030348 syntaxin-3 binding(GO:0030348)
0.6 6.0 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.5 12.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.5 2.5 GO:0004925 prolactin receptor activity(GO:0004925)
0.5 2.5 GO:0046980 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.4 3.5 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.4 2.5 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.3 3.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.3 1.5 GO:0005345 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.3 0.9 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.3 2.3 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.3 1.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.3 0.8 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.3 1.1 GO:0015232 heme transporter activity(GO:0015232)
0.3 1.3 GO:0019770 IgG receptor activity(GO:0019770)
0.2 1.4 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.2 3.8 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.2 0.6 GO:0004923 interleukin-6 receptor activity(GO:0004915) leukemia inhibitory factor receptor activity(GO:0004923) interleukin-6 binding(GO:0019981)
0.2 0.6 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.2 0.6 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.2 2.9 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.2 0.6 GO:0004967 glucagon receptor activity(GO:0004967)
0.2 5.2 GO:0001848 complement binding(GO:0001848)
0.2 0.8 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.2 0.6 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.2 4.5 GO:0051787 misfolded protein binding(GO:0051787)
0.2 1.1 GO:0004103 choline kinase activity(GO:0004103)
0.2 1.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.2 1.6 GO:0019957 C-C chemokine binding(GO:0019957)
0.2 0.5 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.2 0.8 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.1 0.9 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 1.5 GO:0043426 MRF binding(GO:0043426)
0.1 0.6 GO:1904121 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.1 1.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 2.0 GO:0070403 NAD+ binding(GO:0070403)
0.1 0.1 GO:0035877 death effector domain binding(GO:0035877)
0.1 0.3 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.3 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.1 0.4 GO:0019809 spermidine binding(GO:0019809)
0.1 0.9 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.7 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 1.2 GO:0051525 NFAT protein binding(GO:0051525)
0.1 1.1 GO:0046977 TAP binding(GO:0046977)
0.1 0.4 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 0.8 GO:0002046 opsin binding(GO:0002046)
0.1 0.6 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.1 2.1 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 0.6 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 1.3 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.1 0.4 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.1 3.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.4 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.1 0.6 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 9.9 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 0.3 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 0.5 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 1.8 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 0.2 GO:0003979 UDP-glucose 6-dehydrogenase activity(GO:0003979)
0.1 0.7 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 1.3 GO:0070628 proteasome binding(GO:0070628)
0.1 0.2 GO:0004335 galactokinase activity(GO:0004335)
0.1 0.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.8 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.1 1.0 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.6 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.3 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.1 0.5 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.5 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.6 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1 3.3 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 0.7 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 3.7 GO:0038024 cargo receptor activity(GO:0038024)
0.1 0.7 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 1.9 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.1 0.4 GO:0046790 virion binding(GO:0046790)
0.1 0.4 GO:0008430 selenium binding(GO:0008430)
0.1 0.2 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.5 GO:0070061 fructose binding(GO:0070061)
0.1 0.3 GO:0070891 lipoteichoic acid binding(GO:0070891) lipopeptide binding(GO:0071723)
0.0 1.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 8.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 2.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 1.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.1 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.2 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.5 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.7 GO:0048038 quinone binding(GO:0048038)
0.0 1.2 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 1.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.2 GO:0097001 ceramide binding(GO:0097001)
0.0 1.0 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.3 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.2 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.0 0.6 GO:0048018 receptor agonist activity(GO:0048018)
0.0 1.0 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.2 GO:0097643 amylin receptor activity(GO:0097643)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.1 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.0 0.3 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.4 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.3 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.1 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.3 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:1901612 cardiolipin binding(GO:1901612)
0.0 1.1 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.4 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.2 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 6.3 GO:0003924 GTPase activity(GO:0003924)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.6 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.2 GO:0043199 sulfate binding(GO:0043199)
0.0 0.2 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.2 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0035325 Toll-like receptor binding(GO:0035325)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.5 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 2.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.3 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 1.9 GO:0005178 integrin binding(GO:0005178)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.2 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.0 0.1 GO:0019962 interferon receptor activity(GO:0004904) type I interferon receptor activity(GO:0004905) type I interferon binding(GO:0019962)
0.0 0.2 GO:0032813 death receptor binding(GO:0005123) tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0 0.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 2.2 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.5 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0009881 photoreceptor activity(GO:0009881)
0.0 1.2 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.4 GO:0043531 ADP binding(GO:0043531)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 7.0 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.2 4.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.1 12.2 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 4.4 PID IL23 PATHWAY IL23-mediated signaling events
0.1 26.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 2.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 7.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 3.3 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 2.8 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.8 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 2.5 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 4.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.7 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.0 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 2.6 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 1.9 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.4 PID BCR 5PATHWAY BCR signaling pathway
0.0 1.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.3 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.8 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.9 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.3 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.6 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.2 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 3.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.6 PID SHP2 PATHWAY SHP2 signaling
0.0 2.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.2 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.4 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.4 PID AURORA A PATHWAY Aurora A signaling
0.0 0.3 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.3 PID INSULIN PATHWAY Insulin Pathway
0.0 1.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 21.0 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.4 5.7 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.3 3.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.3 2.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.3 3.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.3 2.5 REACTOME DEFENSINS Genes involved in Defensins
0.2 2.5 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 6.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.2 6.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 2.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 0.4 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.1 0.4 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 2.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 0.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 1.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 2.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 2.6 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 0.9 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 0.6 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 1.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 0.9 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 1.0 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 0.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 2.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 2.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 0.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 0.7 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 1.7 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.6 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.7 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.9 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 3.6 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.5 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 7.0 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 2.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.4 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.8 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.6 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.2 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.0 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.0 0.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.2 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.4 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.7 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells