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GSE58827: Dynamics of the Mouse Liver

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Results for Stat1

Z-value: 0.70

Motif logo

Transcription factors associated with Stat1

Gene Symbol Gene ID Gene Info
ENSMUSG00000026104.8 signal transducer and activator of transcription 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Stat1mm10_v2_chr1_+_52119438_521194990.401.6e-02Click!

Activity profile of Stat1 motif

Sorted Z-values of Stat1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_34412334 3.96 ENSMUST00000007449.8
aldo-keto reductase family 1, member B7
chr10_+_95417352 2.88 ENSMUST00000181781.1
RIKEN cDNA 5730420D15 gene
chr6_+_40964760 2.75 ENSMUST00000076638.5
RIKEN cDNA 1810009J06 gene
chr1_+_134182404 2.60 ENSMUST00000153856.1
ENSMUST00000082060.3
ENSMUST00000133701.1
ENSMUST00000132873.1
chitinase 3-like 1
chr1_+_134182150 2.34 ENSMUST00000156873.1
chitinase 3-like 1
chr4_+_115059507 1.93 ENSMUST00000162489.1
T cell acute lymphocytic leukemia 1
chr1_+_107535508 1.81 ENSMUST00000182198.1
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10
chr12_+_109544498 1.68 ENSMUST00000126289.1
maternally expressed 3
chr1_+_171767123 1.58 ENSMUST00000015460.4
signaling lymphocytic activation molecule family member 1
chrX_-_8145713 1.55 ENSMUST00000115615.2
ENSMUST00000115616.1
ENSMUST00000115621.2
RNA binding motif protein 3
chr7_+_43437073 1.55 ENSMUST00000070518.2
natural killer cell group 7 sequence
chr9_+_86743641 1.53 ENSMUST00000179574.1
protease, serine, 35
chrX_-_8145679 1.49 ENSMUST00000115619.1
ENSMUST00000115617.3
ENSMUST00000040010.3
RNA binding motif protein 3
chrX_-_88760312 1.36 ENSMUST00000182943.1
predicted gene, 27000
chrX_-_108664891 1.32 ENSMUST00000178160.1
predicted gene 379
chr9_+_86743616 1.31 ENSMUST00000036426.6
protease, serine, 35
chr14_-_70627008 1.30 ENSMUST00000110984.2
dematin actin binding protein
chr4_-_64046925 1.27 ENSMUST00000107377.3
tenascin C
chr14_-_55713482 1.21 ENSMUST00000168729.1
ENSMUST00000178034.1
transglutaminase 1, K polypeptide
chr10_-_95416850 1.15 ENSMUST00000020215.9
suppressor of cytokine signaling 2
chr7_-_100856289 1.12 ENSMUST00000139604.1
RELT tumor necrosis factor receptor
chr4_+_120666562 1.12 ENSMUST00000094814.4
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
chr1_+_174041933 1.10 ENSMUST00000052975.4
olfactory receptor 433
chr17_+_29090969 1.09 ENSMUST00000119901.1
cyclin-dependent kinase inhibitor 1A (P21)
chr1_-_159168642 1.09 ENSMUST00000077309.1
predicted pseudogene 4953
chr10_-_61784014 1.08 ENSMUST00000020283.4
H2A histone family, member Y2
chr8_-_70608261 0.98 ENSMUST00000049908.9
single stranded DNA binding protein 4
chr1_+_90203980 0.97 ENSMUST00000065587.4
ENSMUST00000159654.1
atypical chemokine receptor 3
chr8_+_86745679 0.97 ENSMUST00000098532.2
predicted gene 10638
chr3_+_97032416 0.94 ENSMUST00000132256.1
ENSMUST00000072600.6
gap junction protein, alpha 5
chr10_-_95417099 0.91 ENSMUST00000135822.1
suppressor of cytokine signaling 2
chr15_-_98482683 0.89 ENSMUST00000023726.3
lactalbumin, alpha
chr11_-_60046477 0.88 ENSMUST00000000310.7
ENSMUST00000102693.2
ENSMUST00000148512.1
phosphatidylethanolamine N-methyltransferase
chr9_-_30922452 0.88 ENSMUST00000065112.6
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 15
chr9_+_86571965 0.88 ENSMUST00000034988.3
ENSMUST00000179212.1
RWD domain containing 2A
chr16_-_20426375 0.87 ENSMUST00000079158.6
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr6_+_41521782 0.86 ENSMUST00000070380.4
protease, serine, 2
chr11_+_69995874 0.86 ENSMUST00000101526.2
PHD finger protein 23
chr14_-_121915774 0.86 ENSMUST00000055475.7
G protein-coupled receptor 18
chrX_-_73930751 0.86 ENSMUST00000155597.1
ENSMUST00000114379.1
renin binding protein
chrX_-_73930834 0.85 ENSMUST00000116578.1
renin binding protein
chr5_+_90561102 0.84 ENSMUST00000094615.4
RIKEN cDNA 5830473C10 gene
chr9_-_44526397 0.83 ENSMUST00000062215.7
chemokine (C-X-C motif) receptor 5
chr11_-_46312220 0.82 ENSMUST00000129474.1
ENSMUST00000093166.4
ENSMUST00000165599.2
cytoplasmic FMR1 interacting protein 2
chr15_-_97831460 0.82 ENSMUST00000079838.7
ENSMUST00000118294.1
histone deacetylase 7
chr11_+_69995777 0.82 ENSMUST00000018716.3
PHD finger protein 23
chr4_-_11965699 0.82 ENSMUST00000108301.1
ENSMUST00000095144.3
ENSMUST00000108302.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr6_-_65144908 0.80 ENSMUST00000031982.4
hematopoietic prostaglandin D synthase
chr18_-_52529847 0.79 ENSMUST00000171470.1
lysyl oxidase
chr16_-_20426322 0.78 ENSMUST00000115547.2
ENSMUST00000096199.4
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr17_-_35516780 0.76 ENSMUST00000160885.1
ENSMUST00000159009.1
ENSMUST00000161012.1
transcription factor 19
chr13_-_34002784 0.71 ENSMUST00000166354.1
ENSMUST00000076532.7
ENSMUST00000171034.1
serine (or cysteine) peptidase inhibitor, clade B, member 6a
chr5_-_140702241 0.71 ENSMUST00000077890.5
ENSMUST00000041783.7
ENSMUST00000142081.1
IQ motif containing E
chr18_-_52529692 0.70 ENSMUST00000025409.7
lysyl oxidase
chr10_+_18235030 0.68 ENSMUST00000181897.1
predicted gene 10827
chr7_+_43781054 0.66 ENSMUST00000014058.9
kallikrein related-peptidase 10
chr3_+_89229046 0.64 ENSMUST00000041142.3
mucin 1, transmembrane
chr17_+_78882003 0.64 ENSMUST00000180880.1
predicted gene, 26637
chr15_-_78305603 0.63 ENSMUST00000096356.3
colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)
chr13_-_34002740 0.62 ENSMUST00000167237.1
ENSMUST00000168400.1
serine (or cysteine) peptidase inhibitor, clade B, member 6a
chr8_+_120736352 0.62 ENSMUST00000047737.3
ENSMUST00000162658.1
interferon regulatory factor 8
chr9_+_44981779 0.62 ENSMUST00000034602.7
CD3 antigen, delta polypeptide
chr8_-_124569696 0.62 ENSMUST00000063278.6
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr3_+_96680093 0.61 ENSMUST00000130429.1
ankyrin repeat domain 35
chr10_-_20312239 0.60 ENSMUST00000092680.2
RIKEN cDNA 4933406P04 gene
chr9_+_124021965 0.58 ENSMUST00000039171.7
chemokine (C-C motif) receptor 3
chr16_-_20425881 0.58 ENSMUST00000077867.3
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr18_-_33463615 0.58 ENSMUST00000051087.8
neuronal regeneration related protein
chr1_-_172027269 0.57 ENSMUST00000027837.6
ENSMUST00000111264.1
vang-like 2 (van gogh, Drosophila)
chr17_-_47834682 0.57 ENSMUST00000066368.6
MyoD family inhibitor
chr18_-_33463747 0.56 ENSMUST00000171533.1
neuronal regeneration related protein
chr18_-_33464007 0.56 ENSMUST00000168890.1
neuronal regeneration related protein
chr1_+_171214013 0.54 ENSMUST00000111328.1
nuclear receptor subfamily 1, group I, member 3
chr16_-_42340595 0.53 ENSMUST00000102817.4
growth associated protein 43
chr3_-_96293953 0.53 ENSMUST00000029748.3
Fc receptor, IgG, high affinity I
chr11_+_82101836 0.53 ENSMUST00000000194.3
chemokine (C-C motif) ligand 12
chr7_-_13054514 0.52 ENSMUST00000182087.1
myeloid zinc finger 1
chr10_-_81266906 0.52 ENSMUST00000046114.4
mitochondrial ribosomal protein L54
chr15_-_93519499 0.51 ENSMUST00000109255.2
prickle homolog 1 (Drosophila)
chr10_+_99443699 0.48 ENSMUST00000167243.1
glutamate decarboxylase 1, pseudogene
chr6_+_115134899 0.48 ENSMUST00000009538.5
ENSMUST00000169345.1
synapsin II
chr12_-_91384403 0.46 ENSMUST00000141429.1
centrosomal protein 128
chr8_-_105568298 0.46 ENSMUST00000005849.5
agouti related protein
chr17_-_24527925 0.45 ENSMUST00000176652.1
TNF receptor-associated factor 7
chr1_-_172027251 0.44 ENSMUST00000138714.1
vang-like 2 (van gogh, Drosophila)
chr7_-_78577771 0.44 ENSMUST00000039438.7
neurotrophic tyrosine kinase, receptor, type 3
chr4_-_129578535 0.41 ENSMUST00000052835.8
family with sequence similarity 167, member B
chr1_+_171213969 0.41 ENSMUST00000005820.4
ENSMUST00000075469.5
ENSMUST00000155126.1
nuclear receptor subfamily 1, group I, member 3
chr17_-_24527830 0.40 ENSMUST00000176353.1
ENSMUST00000176237.1
TNF receptor-associated factor 7
chr11_+_101245996 0.40 ENSMUST00000129680.1
receptor (calcitonin) activity modifying protein 2
chr15_-_37459327 0.40 ENSMUST00000119730.1
ENSMUST00000120746.1
neurocalcin delta
chr11_+_82035569 0.39 ENSMUST00000000193.5
chemokine (C-C motif) ligand 2
chr16_+_19760232 0.39 ENSMUST00000079780.3
ENSMUST00000164397.1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr17_-_27728889 0.38 ENSMUST00000167489.1
ENSMUST00000138970.1
ENSMUST00000114870.1
ENSMUST00000025054.2
SAM pointed domain containing ets transcription factor
chr9_-_121792478 0.37 ENSMUST00000035110.4
hedgehog acyltransferase-like
chr4_-_47010781 0.37 ENSMUST00000135777.1
predicted gene 568
chr5_+_135994796 0.36 ENSMUST00000111142.2
ENSMUST00000111145.3
ENSMUST00000111144.1
ENSMUST00000005072.3
ENSMUST00000130345.1
deltex 2 homolog (Drosophila)
chr7_-_13053684 0.36 ENSMUST00000182490.1
myeloid zinc finger 1
chr19_-_46327121 0.35 ENSMUST00000041391.4
ENSMUST00000096029.5
pleckstrin and Sec7 domain containing
chr17_+_34187789 0.35 ENSMUST00000041633.8
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr17_+_34187545 0.35 ENSMUST00000170086.1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr13_-_41847599 0.34 ENSMUST00000179758.1
androgen dependent TFPI regulating protein
chr2_+_150749036 0.34 ENSMUST00000094467.5
ectonucleoside triphosphate diphosphohydrolase 6
chr4_-_136886187 0.32 ENSMUST00000046384.8
complement component 1, q subcomponent, beta polypeptide
chr11_-_45955465 0.31 ENSMUST00000011398.6
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr7_-_45016224 0.29 ENSMUST00000085383.2
SR-related CTD-associated factor 1
chr12_-_11265768 0.29 ENSMUST00000166117.1
Gen homolog 1, endonuclease (Drosophila)
chr14_+_84443553 0.29 ENSMUST00000071370.5
protocadherin 17
chr13_-_41847626 0.29 ENSMUST00000121404.1
androgen dependent TFPI regulating protein
chr6_+_129397478 0.29 ENSMUST00000112081.2
ENSMUST00000112079.2
C-type lectin domain family 1, member b
chr3_+_96576984 0.28 ENSMUST00000148290.1
predicted gene 16253
chr16_+_19760195 0.28 ENSMUST00000121344.1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr10_-_127070254 0.28 ENSMUST00000060991.4
tetraspanin 31
chr8_-_84687839 0.28 ENSMUST00000001975.4
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr16_-_74411776 0.27 ENSMUST00000116586.2
roundabout homolog 2 (Drosophila)
chr2_+_25180737 0.27 ENSMUST00000104999.2
Notch-regulated ankyrin repeat protein
chr10_+_128303322 0.26 ENSMUST00000005825.6
PAN2 polyA specific ribonuclease subunit homolog (S. cerevisiae)
chr12_+_86082555 0.26 ENSMUST00000054565.6
intraflagellar transport 43 homolog (Chlamydomonas)
chr4_-_49521036 0.26 ENSMUST00000057829.3
mitochondrial ribosomal protein L50
chr4_+_43401232 0.25 ENSMUST00000125399.1
RUN and SH3 domain containing 2
chr13_-_41847482 0.25 ENSMUST00000072012.3
androgen dependent TFPI regulating protein
chr19_-_4615647 0.25 ENSMUST00000113822.2
leucine rich repeat and fibronectin type III domain containing 4
chr6_+_129397297 0.23 ENSMUST00000032262.7
C-type lectin domain family 1, member b
chr11_+_53770014 0.23 ENSMUST00000108920.2
ENSMUST00000140866.1
ENSMUST00000108922.1
interferon regulatory factor 1
chrX_-_10216918 0.23 ENSMUST00000072393.2
ENSMUST00000044598.6
ENSMUST00000073392.4
ENSMUST00000115533.1
ENSMUST00000115532.1
retinitis pigmentosa GTPase regulator
chr2_-_66124994 0.23 ENSMUST00000028378.3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3
chr7_+_19024364 0.22 ENSMUST00000023882.7
symplekin
chr17_-_34187219 0.22 ENSMUST00000173831.1
proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
chr3_-_108210438 0.20 ENSMUST00000117784.1
ENSMUST00000119650.1
ENSMUST00000117409.1
ataxin 7-like 2
chr8_-_111338152 0.20 ENSMUST00000056157.7
ENSMUST00000120432.1
mixed lineage kinase domain-like
chr6_-_122282810 0.20 ENSMUST00000032207.8
killer cell lectin-like receptor subfamily G, member 1
chr8_-_70776650 0.20 ENSMUST00000034296.8
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta)
chr10_+_11609256 0.19 ENSMUST00000052902.7
predicted pseudogene 9797
chr7_-_100583072 0.19 ENSMUST00000152876.1
ENSMUST00000150042.1
mitochondrial ribosomal protein L48
chr5_+_35041539 0.19 ENSMUST00000030985.6
hepatocyte growth factor activator
chr8_-_111337793 0.19 ENSMUST00000145862.1
mixed lineage kinase domain-like
chr7_-_126625676 0.19 ENSMUST00000032961.3
nuclear protein transcription regulator 1
chr9_-_105960642 0.19 ENSMUST00000165165.2
collagen, type VI, alpha 5
chr17_+_34145231 0.18 ENSMUST00000171231.1
histocompatibility 2, class II, locus Mb2
chr3_+_10366903 0.17 ENSMUST00000029049.5
charged multivesicular body protein 4C
chr4_+_115088708 0.17 ENSMUST00000171877.1
ENSMUST00000177647.1
ENSMUST00000106548.2
ENSMUST00000030488.2
PDZK1 interacting protein 1
chr7_-_30944017 0.16 ENSMUST00000062620.7
hepcidin antimicrobial peptide
chr3_-_57294880 0.16 ENSMUST00000171384.1
transmembrane 4 superfamily member 1
chr8_+_70673198 0.14 ENSMUST00000034311.8
LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr18_-_38284391 0.14 ENSMUST00000025311.5
protocadherin 12
chr5_-_149051300 0.14 ENSMUST00000110505.1
high mobility group box 1
chr6_+_127446819 0.14 ENSMUST00000112191.1
poly (ADP-ribose) polymerase family, member 11
chr4_+_83417715 0.12 ENSMUST00000030206.3
ENSMUST00000071544.4
small nuclear RNA activating complex, polypeptide 3
chr6_-_48048911 0.12 ENSMUST00000095944.3
zinc finger protein 777
chr12_+_69372112 0.12 ENSMUST00000050063.7
ADP-ribosylation factor 6
chr2_-_163750169 0.11 ENSMUST00000017841.3
adenosine deaminase
chr11_+_78499087 0.10 ENSMUST00000017488.4
vitronectin
chr1_-_64121456 0.10 ENSMUST00000142009.1
ENSMUST00000114086.1
Kruppel-like factor 7 (ubiquitous)
chr2_+_101886249 0.09 ENSMUST00000028584.7
COMM domain containing 9
chr11_+_96282648 0.09 ENSMUST00000168043.1
homeobox B8
chr9_-_71485893 0.08 ENSMUST00000034720.5
polymerase (RNA) II (DNA directed) polypeptide M
chr5_+_52834009 0.08 ENSMUST00000031072.7
anaphase promoting complex subunit 4
chr10_+_40349265 0.08 ENSMUST00000044672.4
ENSMUST00000095743.2
cyclin-dependent kinase 19
chr2_-_127584668 0.08 ENSMUST00000110368.2
ENSMUST00000077422.5
zinc finger protein 661
chr8_-_111082043 0.07 ENSMUST00000039597.7
C-type lectin domain family 18, member A
chr15_-_37458523 0.07 ENSMUST00000116445.2
neurocalcin delta
chr10_-_78591945 0.07 ENSMUST00000040580.6
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chrX_+_159303266 0.06 ENSMUST00000112491.1
ribosomal protein S6 kinase polypeptide 3
chr7_-_109731708 0.05 ENSMUST00000035372.1
achaete-scute complex homolog 3 (Drosophila)
chr16_+_17508947 0.05 ENSMUST00000023444.3
leucine-zipper-like transcriptional regulator, 1
chr7_+_45783686 0.05 ENSMUST00000118564.1
ENSMUST00000133428.1
lemur tyrosine kinase 3
chr7_+_45783883 0.05 ENSMUST00000072580.5
lemur tyrosine kinase 3
chr11_+_96282529 0.04 ENSMUST00000125410.1
homeobox B8
chr7_-_24316590 0.03 ENSMUST00000108436.1
ENSMUST00000032673.8
zinc finger protein 94
chr18_+_37320374 0.03 ENSMUST00000078271.2
protocadherin beta 5
chr1_+_34005872 0.02 ENSMUST00000182296.1
dystonin
chr12_-_112671564 0.02 ENSMUST00000128300.2
thymoma viral proto-oncogene 1
chr16_-_91931643 0.01 ENSMUST00000023677.3
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr11_-_78536235 0.00 ENSMUST00000017759.2
ENSMUST00000108277.2
tumor necrosis factor, alpha-induced protein 1 (endothelial)

Network of associatons between targets according to the STRING database.

First level regulatory network of Stat1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.5 1.6 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
0.4 1.3 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.4 0.4 GO:1903059 regulation of protein lipidation(GO:1903059)
0.3 1.0 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.3 1.7 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.3 1.3 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.3 0.9 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.3 0.9 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.2 1.7 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.2 0.9 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.2 0.6 GO:1902022 regulation of renal output by angiotensin(GO:0002019) regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331) response to muscle activity involved in regulation of muscle adaptation(GO:0014873) L-lysine transport(GO:1902022)
0.2 1.1 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.2 0.5 GO:0001788 antibody-dependent cellular cytotoxicity(GO:0001788)
0.2 0.5 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.2 0.8 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.9 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.1 0.7 GO:0046967 cytosol to ER transport(GO:0046967)
0.1 1.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.5 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.1 0.4 GO:0002436 immune complex clearance by monocytes and macrophages(GO:0002436) monocyte homeostasis(GO:0035702) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265)
0.1 1.1 GO:0071493 cellular response to UV-B(GO:0071493)
0.1 0.4 GO:0048691 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.1 0.8 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.1 1.1 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.1 0.3 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.1 0.5 GO:0016198 axon choice point recognition(GO:0016198)
0.1 0.2 GO:0034760 negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760)
0.1 2.1 GO:0060396 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.1 0.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 3.0 GO:0009409 response to cold(GO:0009409)
0.1 0.2 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.1 1.7 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 0.2 GO:0060416 response to growth hormone(GO:0060416)
0.1 0.9 GO:0031000 response to caffeine(GO:0031000)
0.1 0.8 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 0.8 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.6 GO:0002551 mast cell chemotaxis(GO:0002551) mast cell migration(GO:0097531)
0.0 0.4 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.6 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.1 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)
0.0 0.5 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 1.3 GO:0071470 cellular response to osmotic stress(GO:0071470)
0.0 0.2 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.1 GO:0043096 germinal center B cell differentiation(GO:0002314) adenosine catabolic process(GO:0006154) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) purine nucleobase salvage(GO:0043096) hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101) purine deoxyribonucleoside metabolic process(GO:0046122) negative regulation of mucus secretion(GO:0070256)
0.0 0.3 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.4 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.8 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 1.0 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.3 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.0 0.6 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.5 GO:0030220 platelet formation(GO:0030220)
0.0 0.6 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.0 0.8 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.0 0.3 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043) regulation of somitogenesis(GO:0014807)
0.0 0.9 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0 0.3 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.0 0.3 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.1 GO:0009301 snRNA transcription(GO:0009301)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.2 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.4 GO:0070266 necroptotic process(GO:0070266)
0.0 0.1 GO:0097284 hepatocyte apoptotic process(GO:0097284)
0.0 0.2 GO:2000194 regulation of female gonad development(GO:2000194)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0033193 Lsd1/2 complex(GO:0033193)
0.4 1.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.3 1.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.3 1.0 GO:0060187 cell pole(GO:0060187)
0.2 1.1 GO:0001740 Barr body(GO:0001740)
0.1 0.4 GO:0044299 C-fiber(GO:0044299)
0.1 0.3 GO:0031251 PAN complex(GO:0031251)
0.1 0.7 GO:0042825 TAP complex(GO:0042825)
0.1 0.6 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.6 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.4 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 1.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.9 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.7 GO:0031527 filopodium membrane(GO:0031527)
0.0 3.8 GO:0015934 large ribosomal subunit(GO:0015934)
0.0 1.6 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.2 GO:0097165 nuclear stress granule(GO:0097165)
0.0 2.0 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.2 GO:0090543 Flemming body(GO:0090543)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.0 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.4 2.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.4 1.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.3 3.0 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.3 1.5 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.3 0.9 GO:0004461 lactose synthase activity(GO:0004461)
0.2 0.9 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.2 0.9 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 1.8 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.2 0.7 GO:0047256 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.2 0.8 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.2 0.8 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.2 1.3 GO:0045545 syndecan binding(GO:0045545)
0.2 1.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.7 GO:0046980 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.1 0.5 GO:0019770 IgG receptor activity(GO:0019770)
0.1 1.7 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 1.0 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 0.3 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.1 0.9 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.4 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.5 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 0.4 GO:0097643 amylin receptor activity(GO:0097643)
0.1 0.6 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0000401 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.0 0.6 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.8 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 1.1 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 1.9 GO:0070888 E-box binding(GO:0070888)
0.0 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 4.6 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.3 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 2.2 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 1.0 GO:0043621 protein self-association(GO:0043621)
0.0 0.2 GO:0070628 proteasome binding(GO:0070628)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 1.0 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 1.1 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.0 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 3.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.0 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.4 PID SHP2 PATHWAY SHP2 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 0.9 REACTOME DEFENSINS Genes involved in Defensins
0.1 0.6 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 0.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.9 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.0 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.6 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.7 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.5 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.9 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.9 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 1.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.1 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 1.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway