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GSE58827: Dynamics of the Mouse Liver

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Results for Rad21_Smc3

Z-value: 1.18

Motif logo

Transcription factors associated with Rad21_Smc3

Gene Symbol Gene ID Gene Info
ENSMUSG00000022314.9 RAD21 cohesin complex component
ENSMUSG00000024974.10 structural maintenance of chromosomes 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Rad21mm10_v2_chr15_-_51991679_51991760-0.876.6e-12Click!
Smc3mm10_v2_chr19_+_53600377_53600435-0.791.1e-08Click!

Activity profile of Rad21_Smc3 motif

Sorted Z-values of Rad21_Smc3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_45069137 9.58 ENSMUST00000067984.7
melatonin receptor 1A
chr15_+_10314102 8.31 ENSMUST00000127467.1
prolactin receptor
chr7_-_19698383 8.29 ENSMUST00000173739.1
apolipoprotein E
chr7_-_19698206 8.23 ENSMUST00000172808.1
ENSMUST00000174191.1
apolipoprotein E
chr18_-_61911783 7.48 ENSMUST00000049378.8
ENSMUST00000166783.1
actin binding LIM protein family, member 3
chr11_+_72435565 7.28 ENSMUST00000100903.2
gamma-glutamyltransferase 6
chr5_+_30921556 6.92 ENSMUST00000031053.8
ketohexokinase
chr19_+_42036025 6.76 ENSMUST00000026172.2
ankyrin repeat domain 2 (stretch responsive muscle)
chr6_+_124570294 6.75 ENSMUST00000184647.1
complement component 1, r subcomponent B
chr6_+_124512615 6.57 ENSMUST00000068593.7
complement component 1, r subcomponent A
chr5_+_30921825 6.55 ENSMUST00000117435.1
ketohexokinase
chr1_+_182564994 6.20 ENSMUST00000048941.7
ENSMUST00000168514.1
calpain 8
chr8_+_45069374 6.02 ENSMUST00000130141.1
melatonin receptor 1A
chr9_+_111439063 5.96 ENSMUST00000111879.3
doublecortin-like kinase 3
chr5_+_30921867 5.77 ENSMUST00000123885.1
ketohexokinase
chr2_+_31887262 5.67 ENSMUST00000138325.1
ENSMUST00000028187.6
laminin gamma 3
chr6_-_85915653 5.58 ENSMUST00000161198.2
camello-like 1
chr4_+_134396320 5.24 ENSMUST00000105869.2
platelet-activating factor acetylhydrolase 2
chr6_-_85915604 5.22 ENSMUST00000174369.1
camello-like 1
chr10_-_31445921 5.01 ENSMUST00000000305.5
tumor protein D52-like 1
chr5_-_151369172 4.51 ENSMUST00000067770.3
RIKEN cDNA D730045B01 gene
chr11_+_103103051 4.48 ENSMUST00000152971.1
acyl-Coenzyme A binding domain containing 4
chr3_+_135281221 4.32 ENSMUST00000120397.1
ENSMUST00000171974.1
ENSMUST00000029817.7
3-hydroxybutyrate dehydrogenase, type 2
chr1_-_51915968 4.09 ENSMUST00000046390.7
myosin IB
chr7_+_127800604 4.05 ENSMUST00000046863.5
ENSMUST00000106272.1
ENSMUST00000139068.1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr7_+_127800844 4.01 ENSMUST00000106271.1
ENSMUST00000138432.1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr5_-_130024280 3.94 ENSMUST00000161640.1
ENSMUST00000161884.1
ENSMUST00000161094.1
argininosuccinate lyase
chr18_-_3281036 3.86 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
cAMP responsive element modulator
chr4_-_57143437 3.77 ENSMUST00000095076.3
ENSMUST00000030142.3
erythrocyte protein band 4.1-like 4b
chr4_-_149307506 3.74 ENSMUST00000055647.8
ENSMUST00000030806.5
ENSMUST00000060537.6
kinesin family member 1B
chr8_+_60506109 3.65 ENSMUST00000079472.2
aminoadipate aminotransferase
chr7_-_34655500 3.64 ENSMUST00000032709.1
potassium channel tetramerisation domain containing 15
chr6_+_85915787 3.63 ENSMUST00000149026.1
Tp53rk binding protein
chr5_+_151368683 3.52 ENSMUST00000181114.1
ENSMUST00000181555.1
RIKEN cDNA 1700028E10 gene
chr9_+_100643605 3.43 ENSMUST00000041418.6
stromal antigen 1
chr12_-_102704896 3.42 ENSMUST00000178697.1
ENSMUST00000046518.5
inositol 1,3,4-triphosphate 5/6 kinase
chr6_+_85915709 3.41 ENSMUST00000113751.1
ENSMUST00000113753.1
ENSMUST00000113752.1
ENSMUST00000067137.7
Tp53rk binding protein
chr7_+_64501687 3.37 ENSMUST00000032732.8
amyloid beta (A4) precursor protein-binding, family A, member 2
chr2_-_166155272 3.32 ENSMUST00000088086.3
sulfatase 2
chr4_-_114908892 3.27 ENSMUST00000068654.3
forkhead box D2
chr2_+_152669461 3.26 ENSMUST00000125366.1
ENSMUST00000109825.1
ENSMUST00000089059.2
ENSMUST00000079247.3
histocompatibility 13
chr2_+_25428699 3.21 ENSMUST00000102919.3
ATP-binding cassette, sub-family A (ABC1), member 2
chr4_+_100095791 3.13 ENSMUST00000039630.5
receptor tyrosine kinase-like orphan receptor 1
chr10_+_29313164 3.12 ENSMUST00000160399.1
enoyl Coenzyme A hydratase domain containing 1
chr2_-_173119402 3.11 ENSMUST00000094287.3
ENSMUST00000179693.1
CCCTC-binding factor (zinc finger protein)-like
chr7_+_64502090 2.97 ENSMUST00000137732.1
amyloid beta (A4) precursor protein-binding, family A, member 2
chr14_+_65666394 2.94 ENSMUST00000022610.8
scavenger receptor class A, member 5 (putative)
chr3_+_118562129 2.93 ENSMUST00000039177.7
dihydropyrimidine dehydrogenase
chr4_+_41762309 2.91 ENSMUST00000108042.2
interleukin 11 receptor, alpha chain 1
chr10_+_29313500 2.91 ENSMUST00000020034.4
enoyl Coenzyme A hydratase domain containing 1
chr10_+_29313227 2.87 ENSMUST00000161605.1
enoyl Coenzyme A hydratase domain containing 1
chr19_-_28963863 2.86 ENSMUST00000161813.1
RIKEN cDNA 4430402I18 gene
chr2_+_58567360 2.84 ENSMUST00000071543.5
uridine phosphorylase 2
chr7_+_64501949 2.84 ENSMUST00000138829.1
amyloid beta (A4) precursor protein-binding, family A, member 2
chr7_+_35119285 2.75 ENSMUST00000042985.9
CCAAT/enhancer binding protein (C/EBP), alpha
chr3_-_63929376 2.74 ENSMUST00000061706.6
RIKEN cDNA E130311K13 gene
chr16_+_18052860 2.74 ENSMUST00000143343.1
DiGeorge syndrome critical region gene 6
chr7_-_127935429 2.73 ENSMUST00000141385.1
ENSMUST00000156152.1
protease, serine, 36
chr17_+_34204080 2.68 ENSMUST00000138491.1
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr7_-_19749464 2.67 ENSMUST00000075447.7
ENSMUST00000108450.3
poliovirus receptor-related 2
chr5_-_25100624 2.65 ENSMUST00000030784.7
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chrX_-_44790146 2.60 ENSMUST00000115056.1
DDB1 and CUL4 associated factor 12-like 1
chr13_+_51100810 2.56 ENSMUST00000095797.5
spindlin 1
chr19_+_5878622 2.55 ENSMUST00000136833.1
ENSMUST00000141362.1
solute carrier family 25, member 45
chr13_+_64248649 2.54 ENSMUST00000181403.1
RIKEN cDNA 1810034E14 gene
chr9_+_100643755 2.53 ENSMUST00000133388.1
stromal antigen 1
chr9_-_107710475 2.52 ENSMUST00000080560.3
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr4_-_141618238 2.52 ENSMUST00000053263.8
transmembrane protein 82
chr18_+_12643329 2.50 ENSMUST00000025294.7
tetratricopeptide repeat domain 39C
chr8_+_119446719 2.49 ENSMUST00000098363.3
N-terminal EF-hand calcium binding protein 2
chr13_-_35027077 2.48 ENSMUST00000170538.1
ENSMUST00000163280.1
enoyl-Coenzyme A delta isomerase 2
chr7_+_16309577 2.48 ENSMUST00000002152.6
BCL2 binding component 3
chr4_+_122995944 2.47 ENSMUST00000106252.2
v-myc myelocytomatosis viral oncogene homolog, lung carcinoma derived (avian)
chrX_-_44790179 2.46 ENSMUST00000060481.2
DDB1 and CUL4 associated factor 12-like 1
chr8_-_69890967 2.45 ENSMUST00000152938.1
YjeF N-terminal domain containing 3
chr9_+_100643448 2.45 ENSMUST00000146312.1
ENSMUST00000129269.1
stromal antigen 1
chr3_+_54735536 2.45 ENSMUST00000044567.3
asparagine-linked glycosylation 5 (dolichyl-phosphate beta-glucosyltransferase)
chr2_+_70661556 2.45 ENSMUST00000112201.1
ENSMUST00000028509.4
ENSMUST00000133432.1
ENSMUST00000112205.1
golgi reassembly stacking protein 2
chr9_+_45906513 2.45 ENSMUST00000039059.6
proprotein convertase subtilisin/kexin type 7
chr8_+_22192800 2.45 ENSMUST00000033866.8
vacuolar protein sorting 36 (yeast)
chr10_-_128409632 2.38 ENSMUST00000172348.1
ENSMUST00000166608.1
ENSMUST00000164199.1
ENSMUST00000171370.1
ENSMUST00000026439.7
nucleic acid binding protein 2
chr7_+_44896125 2.37 ENSMUST00000166552.1
ENSMUST00000168207.1
fuzzy homolog (Drosophila)
chr19_+_5877794 2.37 ENSMUST00000145200.1
ENSMUST00000025732.7
ENSMUST00000125114.1
ENSMUST00000155697.1
solute carrier family 25, member 45
chr4_+_41755210 2.27 ENSMUST00000108038.1
ENSMUST00000084695.4
galactose-1-phosphate uridyl transferase
chrX_-_140600497 2.27 ENSMUST00000112996.2
TSC22 domain family, member 3
chr15_-_76232554 2.21 ENSMUST00000166428.1
plectin
chr14_-_70520254 2.18 ENSMUST00000022693.7
bone morphogenetic protein 1
chr7_+_16310412 2.18 ENSMUST00000136781.1
BCL2 binding component 3
chr1_+_16105774 2.17 ENSMUST00000027053.7
retinol dehydrogenase 10 (all-trans)
chr14_+_65666430 2.15 ENSMUST00000069226.6
scavenger receptor class A, member 5 (putative)
chr10_-_10558199 2.15 ENSMUST00000019974.3
RAB32, member RAS oncogene family
chr18_-_3337467 2.14 ENSMUST00000154135.1
cAMP responsive element modulator
chr11_-_109298121 2.14 ENSMUST00000020920.3
regulator of G-protein signaling 9
chr15_-_77399086 2.13 ENSMUST00000175919.1
ENSMUST00000176074.1
apolipoprotein L 7a
chr19_+_5406815 2.13 ENSMUST00000174412.1
ENSMUST00000153017.2
RIKEN cDNA 4930481A15 gene
chr15_+_99099412 2.12 ENSMUST00000061295.6
DnaJ (Hsp40) homolog, subfamily C, member 22
chr1_+_191575721 2.06 ENSMUST00000045450.5
integrator complex subunit 7
chr19_+_6418731 2.04 ENSMUST00000113462.1
ENSMUST00000077182.6
ENSMUST00000113461.1
neurexin II
chr14_+_77036746 2.01 ENSMUST00000048208.3
ENSMUST00000095625.4
coiled-coil domain containing 122
chr18_-_3337614 1.99 ENSMUST00000150235.1
ENSMUST00000154470.1
cAMP responsive element modulator
chr14_+_52810934 1.98 ENSMUST00000103646.3
T cell receptor alpha variable 10D
chr2_-_65567505 1.96 ENSMUST00000100069.2
sodium channel, voltage-gated, type III, alpha
chr9_-_31211805 1.93 ENSMUST00000072634.7
ENSMUST00000079758.7
amyloid beta (A4) precursor-like protein 2
chr11_+_104231390 1.92 ENSMUST00000106992.3
microtubule-associated protein tau
chr8_+_111536492 1.92 ENSMUST00000168428.1
ENSMUST00000171182.1
zinc and ring finger 1
chr18_-_37935378 1.92 ENSMUST00000025337.7
diaphanous homolog 1 (Drosophila)
chr6_-_129237948 1.91 ENSMUST00000181238.1
ENSMUST00000180379.1
RIKEN cDNA 2310001H17 gene
chr10_-_75773350 1.89 ENSMUST00000001716.7
D-dopachrome tautomerase
chr19_-_47464406 1.89 ENSMUST00000111800.2
ENSMUST00000081619.2
SH3 and PX domains 2A
chr18_-_37935403 1.89 ENSMUST00000080033.6
ENSMUST00000115631.1
diaphanous homolog 1 (Drosophila)
chr1_+_194976342 1.87 ENSMUST00000181226.1
ENSMUST00000181947.1
RIKEN cDNA A330023F24 gene
chr14_+_52844465 1.87 ENSMUST00000181360.1
ENSMUST00000183652.1
T cell receptor alpha variable 12D-1
chr4_-_45530330 1.86 ENSMUST00000061986.5
src homology 2 domain-containing transforming protein B
chr18_-_37935429 1.85 ENSMUST00000115634.1
diaphanous homolog 1 (Drosophila)
chr8_+_71371283 1.84 ENSMUST00000110051.1
ENSMUST00000002469.8
ENSMUST00000110052.1
occludin/ELL domain containing 1
chr1_+_21218575 1.84 ENSMUST00000027065.5
ENSMUST00000027064.7
transmembrane protein 14A
chr1_-_134234492 1.83 ENSMUST00000169927.1
adenosine A1 receptor
chr2_-_73386396 1.83 ENSMUST00000112044.1
ENSMUST00000112043.1
ENSMUST00000076463.5
G protein-coupled receptor 155
chr11_-_116138862 1.83 ENSMUST00000106439.1
mitochondrial ribosomal protein L38
chr7_+_44896077 1.80 ENSMUST00000071207.7
ENSMUST00000166849.1
ENSMUST00000168712.1
ENSMUST00000168389.1
fuzzy homolog (Drosophila)
chr2_+_167688915 1.78 ENSMUST00000070642.3
CCAAT/enhancer binding protein (C/EBP), beta
chr4_-_89311021 1.77 ENSMUST00000097981.4
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr2_-_66256576 1.76 ENSMUST00000125446.2
ENSMUST00000102718.3
tetratricopeptide repeat domain 21B
chr8_+_87472805 1.76 ENSMUST00000180700.2
ENSMUST00000182174.1
ENSMUST00000181159.1
predicted gene 2694
chr10_-_78043580 1.75 ENSMUST00000145975.1
ENSMUST00000130972.1
ENSMUST00000128241.1
ENSMUST00000155021.1
ENSMUST00000140636.1
ENSMUST00000148469.1
ENSMUST00000019257.8
ENSMUST00000105395.2
ENSMUST00000156417.1
ENSMUST00000105396.2
ENSMUST00000154374.1
autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)
chr1_-_150393024 1.74 ENSMUST00000097546.2
ENSMUST00000111913.2
cDNA sequence BC003331
chr11_+_118443471 1.72 ENSMUST00000133558.1
C1q and tumor necrosis factor related protein 1
chr2_+_38998302 1.72 ENSMUST00000112872.1
WD repeat domain 38
chr18_-_3337539 1.71 ENSMUST00000142690.1
ENSMUST00000025069.4
ENSMUST00000082141.5
ENSMUST00000165086.1
ENSMUST00000149803.1
cAMP responsive element modulator
chr6_+_85154992 1.70 ENSMUST00000089584.5
sepiapterin reductase pseudogene 1
chr11_-_53470479 1.70 ENSMUST00000057722.2
predicted gene 9837
chr18_-_56562261 1.69 ENSMUST00000066208.6
ENSMUST00000172734.1
aldehyde dehydrogenase family 7, member A1
chr18_-_56562187 1.69 ENSMUST00000171844.2
aldehyde dehydrogenase family 7, member A1
chr5_+_42067960 1.68 ENSMUST00000087332.4
predicted gene 16223
chr7_-_141437829 1.68 ENSMUST00000019226.7
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr1_+_58113136 1.67 ENSMUST00000040999.7
aldehyde oxidase 3
chr9_-_50528641 1.65 ENSMUST00000034570.5
6-pyruvoyl-tetrahydropterin synthase
chr6_-_85137743 1.65 ENSMUST00000174769.1
ENSMUST00000174286.1
ENSMUST00000045986.7
sepiapterin reductase
chr3_-_5576111 1.65 ENSMUST00000165309.1
ENSMUST00000164828.1
ENSMUST00000071280.5
peroxisomal biogenesis factor 2
chr8_+_87472838 1.65 ENSMUST00000180806.2
predicted gene 2694
chr9_+_44772909 1.63 ENSMUST00000002099.3
intraflagellar transport 46
chr9_+_44772951 1.63 ENSMUST00000128150.1
intraflagellar transport 46
chr11_+_84179852 1.62 ENSMUST00000136463.2
acetyl-Coenzyme A carboxylase alpha
chr14_+_52769753 1.60 ENSMUST00000178768.2
T cell receptor alpha variable 7D-4
chr3_-_121171678 1.59 ENSMUST00000170781.1
ENSMUST00000039761.5
ENSMUST00000106467.1
ENSMUST00000106466.3
ENSMUST00000164925.2
RWD domain containing 3
chr2_-_166155624 1.59 ENSMUST00000109249.2
sulfatase 2
chr14_-_21748610 1.58 ENSMUST00000075040.2
ENSMUST00000183943.1
dual specificity phosphatase 13
chr7_-_141437587 1.58 ENSMUST00000172654.1
ENSMUST00000106006.1
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr13_-_41220395 1.58 ENSMUST00000021793.7
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2
chr3_-_5576233 1.57 ENSMUST00000059021.4
peroxisomal biogenesis factor 2
chr7_-_74554726 1.56 ENSMUST00000107453.1
solute carrier organic anion transporter family, member 3a1
chr11_+_105975204 1.56 ENSMUST00000001964.7
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr13_-_8871751 1.55 ENSMUST00000175958.1
WD repeat domain 37
chr18_-_56562215 1.55 ENSMUST00000170309.1
aldehyde dehydrogenase family 7, member A1
chr5_+_120649188 1.53 ENSMUST00000156722.1
RAS protein activator like 1 (GAP1 like)
chr13_+_54621801 1.53 ENSMUST00000026991.9
ENSMUST00000137413.1
ENSMUST00000135232.1
ENSMUST00000124752.1
Fas associated factor family member 2
chr9_+_110333340 1.53 ENSMUST00000098350.3
SREBF chaperone
chr11_-_82890541 1.53 ENSMUST00000092844.6
ENSMUST00000021033.9
ENSMUST00000018985.8
RAD51 homolog D
chr2_-_112368021 1.52 ENSMUST00000028551.3
ER membrane protein complex subunit 4
chr16_-_94313556 1.50 ENSMUST00000163193.1
holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase)
chr6_+_108783059 1.49 ENSMUST00000032196.6
ADP-ribosylation factor-like 8B
chr1_-_150392719 1.48 ENSMUST00000006167.6
ENSMUST00000094477.2
ENSMUST00000097547.3
cDNA sequence BC003331
chr14_+_52824340 1.48 ENSMUST00000103648.2
T cell receptor alpha variable 11D
chr15_-_76511951 1.47 ENSMUST00000023214.4
diacylglycerol O-acyltransferase 1
chr12_+_8313425 1.47 ENSMUST00000020927.8
HCLS1 binding protein 3
chr19_-_10880370 1.46 ENSMUST00000133303.1
transmembrane protein 109
chr14_+_52753367 1.46 ENSMUST00000180717.1
ENSMUST00000183820.1
T cell receptor alpha variable 6D-4
chr15_-_99087817 1.46 ENSMUST00000064462.3
complement component 1, q subcomponent-like 4
chr7_-_4524229 1.45 ENSMUST00000154913.1
troponin I, cardiac 3
chr11_+_50131342 1.44 ENSMUST00000093138.6
ENSMUST00000101270.4
TBC1 domain family, member 9B
chr4_-_44072712 1.44 ENSMUST00000102936.2
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr11_+_104231573 1.44 ENSMUST00000132977.1
ENSMUST00000132245.1
ENSMUST00000100347.4
microtubule-associated protein tau
chr14_+_53443243 1.43 ENSMUST00000177622.2
T cell receptor alpha variable 7-3
chr7_+_107209439 1.42 ENSMUST00000098135.1
RNA binding motif protein, X-linked-like 2
chr8_-_110168204 1.42 ENSMUST00000003754.6
calbindin 2
chr14_+_53461099 1.41 ENSMUST00000181728.1
T cell receptor alpha variable 7-4
chr13_-_41220162 1.41 ENSMUST00000117096.1
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2
chr8_-_87472576 1.40 ENSMUST00000034076.8
cerebellin 1 precursor protein
chr11_+_78178105 1.40 ENSMUST00000147819.1
TLC domain containing 1
chr9_-_57645561 1.36 ENSMUST00000034863.6
c-src tyrosine kinase
chr8_-_109962127 1.35 ENSMUST00000001722.7
ENSMUST00000051430.6
MARVEL (membrane-associating) domain containing 3
chr3_-_89160155 1.35 ENSMUST00000029686.3
hyperpolarization-activated, cyclic nucleotide-gated K+ 3
chr17_+_28232723 1.35 ENSMUST00000002320.8
peroxisome proliferator activator receptor delta
chr14_-_55758458 1.33 ENSMUST00000001497.7
cell death-inducing DNA fragmentation factor, alpha subunit-like effector B
chr18_-_38211957 1.31 ENSMUST00000159405.1
ENSMUST00000160721.1
protocadherin 1
chr17_-_26090251 1.30 ENSMUST00000040907.6
2-4-dienoyl-Coenzyme A reductase 2, peroxisomal
chr14_+_62555737 1.29 ENSMUST00000039064.7
family with sequence similarity 124, member A
chr14_+_53676141 1.29 ENSMUST00000103662.4
T cell receptor alpha variable 9-4
chr11_+_104231465 1.28 ENSMUST00000145227.1
microtubule-associated protein tau
chr1_-_55363462 1.28 ENSMUST00000159398.1
bol, boule-like (Drosophila)
chr7_+_141455198 1.28 ENSMUST00000164016.1
ENSMUST00000064151.6
ENSMUST00000169665.1
patatin-like phospholipase domain containing 2
chr18_+_74442500 1.28 ENSMUST00000074157.6
myosin VB
chr19_+_44989073 1.27 ENSMUST00000026225.8
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr11_-_76763550 1.25 ENSMUST00000010536.8
golgi SNAP receptor complex member 1
chr7_-_45136391 1.25 ENSMUST00000146760.1
FMS-like tyrosine kinase 3 ligand
chr9_+_107888129 1.24 ENSMUST00000035202.2
MON1 homolog A (yeast)
chr13_+_117602439 1.24 ENSMUST00000006991.7
hyperpolarization-activated, cyclic nucleotide-gated K+ 1
chr5_+_140331860 1.22 ENSMUST00000071881.3
ENSMUST00000050205.5
ENSMUST00000110827.1
nudix (nucleoside diphosphate linked moiety X)-type motif 1
chr14_+_52792208 1.20 ENSMUST00000178426.2
T cell receptor alpha variable 9D-1
chr5_-_66618636 1.20 ENSMUST00000162382.1
ENSMUST00000160870.1
ENSMUST00000087256.5
ENSMUST00000160103.1
ENSMUST00000162349.1
amyloid beta (A4) precursor protein-binding, family B, member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Rad21_Smc3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.5 16.5 GO:1903000 regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002)
4.8 19.2 GO:0061625 fructose catabolic process(GO:0006001) response to sucrose(GO:0009744) response to disaccharide(GO:0034285) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
1.4 4.2 GO:2000314 negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
1.4 8.3 GO:0038161 prolactin signaling pathway(GO:0038161)
1.3 3.9 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
1.2 4.9 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
1.2 4.7 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
1.1 3.3 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
1.0 2.9 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859) thymidine metabolic process(GO:0046104)
1.0 15.6 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.9 8.1 GO:0035754 B cell chemotaxis(GO:0035754)
0.9 2.7 GO:0046968 positive regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002591) peptide antigen transport(GO:0046968)
0.8 2.5 GO:1904020 positive regulation of adenosine receptor signaling pathway(GO:0060168) regulation of G-protein coupled receptor internalization(GO:1904020)
0.8 2.3 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.7 2.7 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.6 5.8 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.6 2.4 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.6 1.8 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241) regulation of nucleoside transport(GO:0032242) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
0.6 1.7 GO:0002465 peripheral T cell tolerance induction(GO:0002458) peripheral tolerance induction(GO:0002465) regulation of thymocyte migration(GO:2000410)
0.5 1.6 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039) regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.5 7.3 GO:0006751 glutathione catabolic process(GO:0006751)
0.5 1.6 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.5 1.5 GO:1901738 regulation of vitamin A metabolic process(GO:1901738)
0.5 1.9 GO:0046684 response to pyrethroid(GO:0046684)
0.5 1.4 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.5 3.2 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.4 6.8 GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0043619)
0.4 2.5 GO:0097491 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.4 1.3 GO:0048209 regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
0.4 1.2 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.4 1.2 GO:0046061 dATP catabolic process(GO:0046061)
0.4 2.3 GO:0032439 endosome localization(GO:0032439)
0.4 1.1 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.4 2.3 GO:0098963 dendritic transport of ribonucleoprotein complex(GO:0098961) dendritic transport of messenger ribonucleoprotein complex(GO:0098963) anterograde dendritic transport of messenger ribonucleoprotein complex(GO:0098964)
0.4 1.9 GO:0072675 osteoclast fusion(GO:0072675)
0.4 1.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313) protein K27-linked deubiquitination(GO:1990167)
0.4 3.3 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.4 0.7 GO:1904954 canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.4 2.2 GO:0060431 primary lung bud formation(GO:0060431)
0.4 1.4 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
0.3 5.4 GO:0019184 nonribosomal peptide biosynthetic process(GO:0019184)
0.3 1.7 GO:0009115 xanthine catabolic process(GO:0009115) xanthine metabolic process(GO:0046110)
0.3 3.6 GO:0042436 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218) kynurenine metabolic process(GO:0070189)
0.3 3.2 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.3 2.7 GO:0000050 urea cycle(GO:0000050)
0.3 1.5 GO:1903232 melanosome assembly(GO:1903232)
0.3 1.5 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.3 4.1 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.3 1.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.3 0.8 GO:0021759 globus pallidus development(GO:0021759)
0.3 1.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.3 1.0 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.3 1.5 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.3 1.0 GO:0002636 positive regulation of germinal center formation(GO:0002636)
0.2 3.0 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.2 0.7 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
0.2 1.5 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.2 4.8 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.2 3.7 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.2 1.1 GO:1904688 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.2 1.4 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.2 1.8 GO:0097421 liver regeneration(GO:0097421)
0.2 4.0 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.2 0.9 GO:0009223 pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.2 1.1 GO:0032364 oxygen homeostasis(GO:0032364)
0.2 1.0 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.2 1.9 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.2 2.5 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.2 10.2 GO:0006958 complement activation, classical pathway(GO:0006958)
0.2 0.8 GO:1902530 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.2 0.6 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.2 1.0 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.2 1.7 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.2 1.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.2 4.6 GO:0034389 lipid particle organization(GO:0034389)
0.2 4.5 GO:0060285 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.2 11.6 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.2 2.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 0.5 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.2 1.0 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.2 0.6 GO:0070368 positive regulation of hepatocyte differentiation(GO:0070368)
0.2 0.6 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.2 1.4 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.1 1.8 GO:0060253 negative regulation of glial cell proliferation(GO:0060253)
0.1 2.1 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.1 0.4 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 0.6 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.3 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.1 0.6 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.1 0.3 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.1 2.9 GO:0046697 decidualization(GO:0046697)
0.1 0.4 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1 0.7 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.1 0.8 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 1.8 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.1 0.5 GO:0009816 defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.1 1.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 1.2 GO:0051503 adenine nucleotide transport(GO:0051503)
0.1 11.0 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.1 0.7 GO:0000429 carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436)
0.1 0.6 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.1 3.8 GO:0014002 astrocyte development(GO:0014002)
0.1 1.3 GO:1902414 protein localization to cell junction(GO:1902414)
0.1 0.8 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1 0.7 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.6 GO:1903978 regulation of microglial cell activation(GO:1903978)
0.1 3.3 GO:0015813 L-glutamate transport(GO:0015813)
0.1 4.7 GO:0070207 protein homotrimerization(GO:0070207)
0.1 0.8 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.1 2.6 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.3 GO:0043181 vacuolar sequestering(GO:0043181)
0.1 0.5 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1 2.1 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.1 0.9 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 3.1 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.1 1.6 GO:0006857 oligopeptide transport(GO:0006857)
0.1 1.5 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.1 0.5 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.1 2.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 1.1 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 1.2 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.1 0.5 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.1 0.7 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.9 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.7 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1 1.9 GO:0001967 suckling behavior(GO:0001967)
0.1 0.3 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.1 8.4 GO:1903749 positive regulation of establishment of protein localization to mitochondrion(GO:1903749) positive regulation of protein targeting to mitochondrion(GO:1903955)
0.1 0.2 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.1 0.3 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.1 0.4 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.1 1.1 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 1.0 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.1 2.0 GO:0098596 vocal learning(GO:0042297) imitative learning(GO:0098596)
0.1 1.6 GO:0070200 establishment of protein localization to telomere(GO:0070200)
0.1 1.0 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.4 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 2.1 GO:0042438 melanin biosynthetic process(GO:0042438)
0.1 0.9 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 0.7 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 1.8 GO:0007143 female meiotic division(GO:0007143)
0.1 0.5 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 0.3 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.7 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.9 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.4 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.1 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.1 0.6 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 0.7 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 1.8 GO:0035855 megakaryocyte development(GO:0035855)
0.1 0.5 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.1 0.2 GO:1903027 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.1 1.5 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.1 6.0 GO:1900181 negative regulation of protein localization to nucleus(GO:1900181)
0.1 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1 0.2 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.1 2.2 GO:0061036 positive regulation of cartilage development(GO:0061036)
0.1 0.3 GO:0060178 regulation of exocyst localization(GO:0060178)
0.1 0.7 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.1 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.8 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 0.4 GO:0015808 L-alanine transport(GO:0015808)
0.1 0.6 GO:0021756 striatum development(GO:0021756)
0.1 0.5 GO:0050957 equilibrioception(GO:0050957)
0.1 0.5 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.8 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.9 GO:0044406 adhesion of symbiont to host(GO:0044406)
0.0 4.2 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.2 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 1.3 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 6.1 GO:0008033 tRNA processing(GO:0008033)
0.0 2.7 GO:0019217 regulation of fatty acid metabolic process(GO:0019217)
0.0 0.5 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.3 GO:0003352 regulation of cilium movement(GO:0003352) protein polyglutamylation(GO:0018095)
0.0 5.9 GO:0007586 digestion(GO:0007586)
0.0 1.0 GO:0060416 response to growth hormone(GO:0060416)
0.0 0.8 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.7 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.0 1.6 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 1.2 GO:0033273 response to vitamin(GO:0033273)
0.0 0.9 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 0.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.0 4.1 GO:0006892 post-Golgi vesicle-mediated transport(GO:0006892)
0.0 0.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.4 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.5 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.1 GO:0045324 late endosome to vacuole transport(GO:0045324)
0.0 2.5 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 9.0 GO:0035264 multicellular organism growth(GO:0035264)
0.0 0.2 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 1.0 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.7 GO:0046686 response to cadmium ion(GO:0046686)
0.0 1.3 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)
0.0 0.9 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 0.6 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.3 GO:0050687 negative regulation of defense response to virus(GO:0050687)
0.0 0.9 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.1 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.7 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 1.5 GO:0032418 lysosome localization(GO:0032418)
0.0 4.4 GO:0016042 lipid catabolic process(GO:0016042)
0.0 2.4 GO:0007030 Golgi organization(GO:0007030)
0.0 0.8 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.0 0.7 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.1 GO:1903214 regulation of protein targeting to mitochondrion(GO:1903214)
0.0 0.6 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 1.7 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.1 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.1 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.8 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 1.0 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 1.3 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.0 0.2 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 1.0 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.2 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 1.9 GO:0046330 positive regulation of JNK cascade(GO:0046330)
0.0 0.1 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.0 1.9 GO:0007601 visual perception(GO:0007601)
0.0 0.6 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 1.6 GO:0098656 anion transmembrane transport(GO:0098656)
0.0 0.5 GO:0050919 negative chemotaxis(GO:0050919)
0.0 2.1 GO:0001764 neuron migration(GO:0001764)
0.0 0.4 GO:0006506 GPI anchor biosynthetic process(GO:0006506)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 16.5 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
1.5 4.5 GO:0036488 CHOP-C/EBP complex(GO:0036488)
1.4 7.0 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.8 2.4 GO:0000814 ESCRT II complex(GO:0000814)
0.6 5.8 GO:0045298 tubulin complex(GO:0045298)
0.5 3.3 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.5 2.4 GO:0070876 SOSS complex(GO:0070876)
0.4 3.5 GO:0042825 TAP complex(GO:0042825)
0.4 1.2 GO:0098855 HCN channel complex(GO:0098855)
0.4 2.8 GO:0045098 type III intermediate filament(GO:0045098)
0.3 1.0 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.3 2.1 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.3 1.5 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.3 1.2 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.3 1.3 GO:0044316 cone cell pedicle(GO:0044316)
0.3 2.6 GO:0070545 PeBoW complex(GO:0070545)
0.2 3.9 GO:0070852 cell body fiber(GO:0070852)
0.2 1.5 GO:1990584 cardiac Troponin complex(GO:1990584)
0.2 0.7 GO:0016939 kinesin II complex(GO:0016939)
0.2 2.6 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.2 1.1 GO:0097361 CIA complex(GO:0097361)
0.2 1.9 GO:0030991 intraciliary transport particle A(GO:0030991)
0.2 5.8 GO:0030992 intraciliary transport particle B(GO:0030992)
0.2 1.8 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.2 0.5 GO:0060473 cortical granule(GO:0060473)
0.2 3.7 GO:0005797 Golgi medial cisterna(GO:0005797)
0.2 0.5 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.1 4.0 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1 1.6 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.7 GO:0002142 stereocilia ankle link complex(GO:0002142)
0.1 2.1 GO:0032039 integrator complex(GO:0032039)
0.1 0.5 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.1 1.8 GO:0031209 SCAR complex(GO:0031209)
0.1 0.7 GO:1990130 Iml1 complex(GO:1990130) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 4.1 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 2.2 GO:0030056 hemidesmosome(GO:0030056)
0.1 1.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 1.3 GO:1990909 Wnt signalosome(GO:1990909)
0.1 2.2 GO:0097225 sperm midpiece(GO:0097225)
0.1 5.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 1.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.1 1.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 2.7 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 5.2 GO:0000791 euchromatin(GO:0000791)
0.1 2.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 1.0 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.7 GO:0032279 asymmetric synapse(GO:0032279)
0.1 1.5 GO:0005652 nuclear lamina(GO:0005652)
0.1 0.9 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.1 9.4 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 1.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.9 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.5 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.5 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 0.8 GO:0005869 dynactin complex(GO:0005869)
0.1 3.4 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.8 GO:0016589 NURF complex(GO:0016589)
0.1 0.2 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.1 0.4 GO:0005838 proteasome regulatory particle(GO:0005838)
0.1 0.6 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.9 GO:0030008 TRAPP complex(GO:0030008)
0.1 1.1 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.8 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 2.3 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 2.7 GO:0009925 basal plasma membrane(GO:0009925)
0.0 7.3 GO:0072562 blood microparticle(GO:0072562)
0.0 4.1 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 5.2 GO:0005604 basement membrane(GO:0005604)
0.0 0.4 GO:0070578 RISC-loading complex(GO:0070578)
0.0 17.8 GO:0043235 receptor complex(GO:0043235)
0.0 0.3 GO:0030914 STAGA complex(GO:0030914)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 1.4 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 1.0 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 2.5 GO:0016459 myosin complex(GO:0016459)
0.0 3.7 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 1.9 GO:0042734 presynaptic membrane(GO:0042734)
0.0 2.6 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.5 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 1.1 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.6 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 6.5 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 1.3 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 9.2 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 2.1 GO:0001650 fibrillar center(GO:0001650)
0.0 0.1 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 1.2 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.4 GO:0043034 costamere(GO:0043034)
0.0 2.2 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
6.4 19.2 GO:0004454 ketohexokinase activity(GO:0004454)
5.5 16.5 GO:0046911 metal chelating activity(GO:0046911)
3.1 15.6 GO:0008502 melatonin receptor activity(GO:0008502)
3.0 8.9 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
1.7 8.3 GO:0004925 prolactin receptor activity(GO:0004925)
1.5 4.4 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
1.2 4.9 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
1.1 3.4 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
1.1 6.8 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
1.0 5.1 GO:0070287 ferritin receptor activity(GO:0070287)
1.0 3.9 GO:0016842 amidine-lyase activity(GO:0016842)
1.0 4.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.8 5.8 GO:0099609 microtubule lateral binding(GO:0099609)
0.7 2.9 GO:0019970 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.7 2.1 GO:0035650 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.7 3.3 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.6 2.5 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.6 7.3 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.6 8.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.6 2.8 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.6 1.7 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.5 2.7 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.5 2.7 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.5 5.2 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.5 1.5 GO:0009374 biotin binding(GO:0009374)
0.5 2.5 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.5 1.5 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.5 1.4 GO:0098918 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.4 1.3 GO:0016501 prostacyclin receptor activity(GO:0016501)
0.4 1.3 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.4 2.6 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.4 0.8 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.4 2.9 GO:0002054 nucleobase binding(GO:0002054)
0.4 3.3 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.4 1.2 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.4 3.2 GO:0043426 MRF binding(GO:0043426)
0.4 1.6 GO:0070573 tripeptidyl-peptidase activity(GO:0008240) bradykinin receptor binding(GO:0031711) metallodipeptidase activity(GO:0070573)
0.4 2.7 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.3 1.7 GO:0016726 aldehyde oxidase activity(GO:0004031) xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.3 2.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.3 1.5 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.3 1.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.3 0.8 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.3 2.6 GO:0035473 lipase binding(GO:0035473)
0.3 3.3 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.2 3.0 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.2 1.4 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.2 5.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 1.5 GO:0000150 recombinase activity(GO:0000150)
0.2 1.9 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 2.1 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.2 1.5 GO:0030172 troponin C binding(GO:0030172)
0.2 2.3 GO:0070569 uridylyltransferase activity(GO:0070569)
0.2 2.1 GO:0008494 translation activator activity(GO:0008494)
0.2 4.1 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.2 1.8 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.2 1.6 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.2 2.4 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.2 11.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.2 1.0 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.2 2.7 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.2 0.5 GO:0070002 glutamic-type peptidase activity(GO:0070002)
0.2 4.2 GO:0008483 transaminase activity(GO:0008483)
0.2 0.6 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.2 2.5 GO:0045499 chemorepellent activity(GO:0045499)
0.2 1.6 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.2 1.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 0.6 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.4 GO:0051747 cytosine C-5 DNA demethylase activity(GO:0051747)
0.1 1.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.4 GO:0005302 L-tyrosine transmembrane transporter activity(GO:0005302)
0.1 0.7 GO:0033142 progesterone receptor binding(GO:0033142)
0.1 0.7 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 1.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 0.7 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.1 1.8 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 1.8 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 1.4 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 1.0 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 1.1 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.9 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 19.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.6 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 1.8 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 3.0 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.1 0.7 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 1.8 GO:0031402 sodium ion binding(GO:0031402)
0.1 0.4 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.5 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.7 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 3.4 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.3 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.4 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 0.5 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.3 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 3.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 1.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 2.0 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1 2.5 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.3 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 0.2 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.6 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.2 GO:0032405 exodeoxyribonuclease III activity(GO:0008853) MutLalpha complex binding(GO:0032405)
0.0 1.6 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.7 GO:0048018 receptor agonist activity(GO:0048018)
0.0 3.1 GO:0019894 kinesin binding(GO:0019894)
0.0 1.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 1.0 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 1.0 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 2.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 2.6 GO:0015485 cholesterol binding(GO:0015485)
0.0 2.3 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.3 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 1.9 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 1.7 GO:0045182 translation regulator activity(GO:0045182)
0.0 7.2 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.2 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.5 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.2 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.0 0.4 GO:0035198 miRNA binding(GO:0035198)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 1.1 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 3.8 GO:0051117 ATPase binding(GO:0051117)
0.0 2.1 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 1.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.3 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.0 0.6 GO:0005537 mannose binding(GO:0005537)
0.0 1.3 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.5 GO:0032183 SUMO binding(GO:0032183)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.3 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.5 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.9 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.0 13.0 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 1.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.9 GO:0030507 spectrin binding(GO:0030507)
0.0 0.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.0 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.4 GO:0004629 phospholipase C activity(GO:0004629)
0.0 0.5 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.7 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.9 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.7 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 1.1 GO:0005518 collagen binding(GO:0005518)
0.0 0.5 GO:0005496 steroid binding(GO:0005496)
0.0 0.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.1 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.5 GO:0051018 protein kinase A binding(GO:0051018)
0.0 1.7 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.0 0.2 GO:0043531 ADP binding(GO:0043531)
0.0 0.0 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 3.0 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.6 GO:0043022 ribosome binding(GO:0043022)
0.0 1.1 GO:0004222 metalloendopeptidase activity(GO:0004222)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 9.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.2 3.1 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 3.6 PID CONE PATHWAY Visual signal transduction: Cones
0.1 0.6 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 3.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 5.7 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 0.7 PID IFNG PATHWAY IFN-gamma pathway
0.1 6.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 6.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 6.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 4.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 1.3 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.5 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.0 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.5 PID SHP2 PATHWAY SHP2 signaling
0.0 0.5 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 6.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.3 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.8 PID P73PATHWAY p73 transcription factor network
0.0 0.7 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 1.8 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.5 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.3 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 18.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.6 8.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.4 8.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.3 5.8 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.3 7.5 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.3 7.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2 3.3 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.2 3.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.2 1.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2 2.7 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2 0.7 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.2 5.7 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.2 1.6 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.2 2.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 3.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 3.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 2.7 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 2.3 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.1 1.0 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 0.8 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 1.7 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 6.0 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 5.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 2.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 15.6 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 1.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 1.8 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 1.0 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 11.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.8 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.8 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.4 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 2.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.1 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 1.2 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.6 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.7 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.6 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 1.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.6 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.8 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 1.5 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.8 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 1.2 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 1.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants