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GSE58827: Dynamics of the Mouse Liver

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Results for Nr5a2

Z-value: 1.70

Motif logo

Transcription factors associated with Nr5a2

Gene Symbol Gene ID Gene Info
ENSMUSG00000026398.8 nuclear receptor subfamily 5, group A, member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr5a2mm10_v2_chr1_-_136953600_136953630-0.447.9e-03Click!

Activity profile of Nr5a2 motif

Sorted Z-values of Nr5a2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_60582152 14.44 ENSMUST00000098047.2
major urinary protein 10
chr4_-_61674094 13.40 ENSMUST00000098040.3
major urinary protein 18
chr4_-_61303998 12.87 ENSMUST00000071005.8
ENSMUST00000075206.5
major urinary protein 14
chr4_-_60421933 12.69 ENSMUST00000107506.2
ENSMUST00000122381.1
ENSMUST00000118759.1
ENSMUST00000122177.1
major urinary protein 9
chr4_-_60662358 12.66 ENSMUST00000084544.4
ENSMUST00000098046.3
major urinary protein 11
chr4_-_60222580 12.65 ENSMUST00000095058.4
ENSMUST00000163931.1
major urinary protein 8
chr4_-_61303802 12.32 ENSMUST00000125461.1
major urinary protein 14
chr4_-_60139857 11.86 ENSMUST00000107490.4
ENSMUST00000074700.2
major urinary protein 2
chr4_-_62054112 11.62 ENSMUST00000074018.3
major urinary protein 20
chr13_+_21722057 5.54 ENSMUST00000110476.3
histone cluster 1, H2bm
chr2_+_155611175 4.04 ENSMUST00000092995.5
myosin, heavy chain 7B, cardiac muscle, beta
chr13_-_56296551 3.79 ENSMUST00000021970.9
chemokine (C-X-C motif) ligand 14
chr2_-_131160006 3.48 ENSMUST00000103188.3
ENSMUST00000133602.1
ENSMUST00000028800.5
RIKEN cDNA 1700037H04 gene
chr8_+_84970068 3.35 ENSMUST00000164807.1
peroxiredoxin 2
chr12_-_110978618 3.06 ENSMUST00000140788.1
ankyrin repeat domain 9
chr12_-_110978981 2.97 ENSMUST00000135131.1
ENSMUST00000043459.6
ENSMUST00000128353.1
ankyrin repeat domain 9
chr14_-_21848924 2.90 ENSMUST00000124549.1
catechol-O-methyltransferase domain containing 1
chr12_-_110978943 2.83 ENSMUST00000142012.1
ankyrin repeat domain 9
chr4_+_63362443 2.68 ENSMUST00000075341.3
orosomucoid 2
chr12_+_80692591 2.50 ENSMUST00000140770.1
pleckstrin homology domain containing, family D (with coiled-coil domains) member 1
chr13_+_21787461 2.38 ENSMUST00000110473.2
ENSMUST00000102982.1
histone cluster 1, H2bp
chr9_-_106891401 2.32 ENSMUST00000069036.7
mesencephalic astrocyte-derived neurotrophic factor
chr13_-_21716143 2.32 ENSMUST00000091756.1
histone cluster 1, H2bl
chr13_-_21787218 2.31 ENSMUST00000091751.2
histone cluster 1, H2an
chr11_+_74619594 2.21 ENSMUST00000100866.2
RIKEN cDNA E130309D14 gene
chrX_-_141874870 2.16 ENSMUST00000182079.1
predicted gene 15294
chr13_-_21753851 2.15 ENSMUST00000074752.2
histone cluster 1, H2ak
chr19_-_46672883 2.08 ENSMUST00000026012.7
cytochrome P450, family 17, subfamily a, polypeptide 1
chr11_+_6415443 2.05 ENSMUST00000132846.1
peptidylprolyl isomerase A
chr15_-_103252810 2.04 ENSMUST00000154510.1
nuclear factor, erythroid derived 2
chr19_+_6400611 2.02 ENSMUST00000113467.1
RAS, guanyl releasing protein 2
chr1_+_92831614 2.01 ENSMUST00000045970.6
glypican 1
chr11_-_72266596 1.90 ENSMUST00000021161.6
ENSMUST00000140167.1
solute carrier family 13 (sodium-dependent citrate transporter), member 5
chr12_+_105032638 1.88 ENSMUST00000021522.3
glutaredoxin 5 homolog (S. cerevisiae)
chr4_+_45184815 1.85 ENSMUST00000134280.1
ENSMUST00000044773.5
FERM and PDZ domain containing 1
chr1_-_167393826 1.72 ENSMUST00000028005.2
microsomal glutathione S-transferase 3
chr1_+_75435930 1.71 ENSMUST00000037796.7
ENSMUST00000113584.1
ENSMUST00000145166.1
ENSMUST00000143730.1
ENSMUST00000133418.1
ENSMUST00000144874.1
ENSMUST00000140287.1
GDP-mannose pyrophosphorylase A
chr18_+_77185815 1.70 ENSMUST00000079618.4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr13_+_119623819 1.69 ENSMUST00000099241.2
chemokine (C-C motif) ligand 28
chr15_+_85116829 1.66 ENSMUST00000105085.1
predicted gene 10923
chr4_+_13751297 1.65 ENSMUST00000105566.2
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr6_+_83349446 1.61 ENSMUST00000136501.1
bolA-like 3 (E. coli)
chr2_-_26021679 1.46 ENSMUST00000036509.7
ubiquitin associated domain containing 1
chr12_-_34291092 1.45 ENSMUST00000166546.2
predicted gene, 18025
chr2_-_25571301 1.45 ENSMUST00000095117.3
ENSMUST00000114223.1
MAM domain containing 4
chr15_+_76343504 1.44 ENSMUST00000023210.6
cytochrome c-1
chr13_+_119690462 1.42 ENSMUST00000179869.1
3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1
chr4_+_138250403 1.41 ENSMUST00000105824.1
ENSMUST00000124239.1
ENSMUST00000105818.1
SH2 domain containing 5
kinesin family member 17
chr6_-_76497631 1.41 ENSMUST00000097218.5
predicted pseudogene 9008
chr11_-_102407315 1.41 ENSMUST00000149777.1
ENSMUST00000154001.1
solute carrier family 25, member 39
chr3_+_32736990 1.40 ENSMUST00000127477.1
ENSMUST00000121778.1
ENSMUST00000154257.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5
chr3_-_54915867 1.39 ENSMUST00000070342.3
serine rich and transmembrane domain containing 1
chr4_+_138250462 1.35 ENSMUST00000105823.1
SH2 domain containing 5
chr11_-_3504766 1.34 ENSMUST00000044507.5
inositol polyphosphate 5-phosphatase J
chr8_+_84969767 1.33 ENSMUST00000109733.1
peroxiredoxin 2
chr2_-_26021532 1.32 ENSMUST00000136750.1
ubiquitin associated domain containing 1
chr19_-_37178011 1.32 ENSMUST00000133988.1
cytoplasmic polyadenylation element binding protein 3
chr8_+_84969824 1.31 ENSMUST00000125893.1
peroxiredoxin 2
chr1_-_52091066 1.31 ENSMUST00000105087.1
predicted gene 3940
chr19_+_6400523 1.30 ENSMUST00000146831.1
ENSMUST00000035716.8
ENSMUST00000138555.1
ENSMUST00000167240.1
RAS, guanyl releasing protein 2
chr15_-_64382908 1.29 ENSMUST00000177374.1
ENSMUST00000023008.9
ENSMUST00000110115.2
ENSMUST00000110114.3
ArfGAP with SH3 domain, ankyrin repeat and PH domain1
chr1_+_45981548 1.29 ENSMUST00000085632.2
ribosomal protein 23A, pseudogene 1
chr18_+_6332587 1.29 ENSMUST00000097682.2
ribosomal protein L27, pseudogene 3
chr17_+_24470393 1.28 ENSMUST00000053024.6
phosphoglycolate phosphatase
chr15_+_98108465 1.28 ENSMUST00000051226.6
phosphofructokinase, muscle
chr3_-_108085346 1.27 ENSMUST00000078912.5
adenosine monophosphate deaminase 2
chr12_-_71136611 1.25 ENSMUST00000021486.8
ENSMUST00000166120.1
translocase of inner mitochondrial membrane 9
chr3_+_96576984 1.23 ENSMUST00000148290.1
predicted gene 16253
chr12_-_16589743 1.23 ENSMUST00000111067.2
ENSMUST00000067124.5
lipin 1
chr10_+_94198955 1.21 ENSMUST00000020209.9
ENSMUST00000179990.1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr14_+_75455957 1.21 ENSMUST00000164848.1
seven in absentia homolog 3 (Drosophila)
chrX_+_71556874 1.20 ENSMUST00000123100.1
high mobility group box 3
chr19_+_6399746 1.19 ENSMUST00000113468.1
RAS, guanyl releasing protein 2
chr19_+_6399857 1.19 ENSMUST00000146601.1
ENSMUST00000150713.1
RAS, guanyl releasing protein 2
chrX_+_75382384 1.19 ENSMUST00000033541.4
FUN14 domain containing 2
chr14_-_77252327 1.18 ENSMUST00000099431.4
predicted gene 10132
chr13_+_22043189 1.17 ENSMUST00000110452.1
histone cluster 1, H2bj
chr6_-_125165576 1.17 ENSMUST00000183272.1
ENSMUST00000182052.1
ENSMUST00000182277.1
glyceraldehyde-3-phosphate dehydrogenase
chr2_+_102706356 1.16 ENSMUST00000123759.1
ENSMUST00000111212.1
ENSMUST00000005220.4
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr9_-_106891870 1.16 ENSMUST00000160503.1
ENSMUST00000159620.2
ENSMUST00000160978.1
mesencephalic astrocyte-derived neurotrophic factor
chr19_-_60874526 1.16 ENSMUST00000025961.6
peroxiredoxin 3
chr7_+_30184160 1.15 ENSMUST00000098594.2
cytochrome c oxidase subunit VIIa 1
chr4_-_148159571 1.13 ENSMUST00000167160.1
ENSMUST00000151246.1
F-box protein 44
chr4_-_129227883 1.09 ENSMUST00000106051.1
expressed sequence C77080
chr14_+_34170640 1.08 ENSMUST00000104925.3
ribosomal protein L23A, pseudogene 3
chr6_+_29853746 1.08 ENSMUST00000064872.6
ENSMUST00000152581.1
ENSMUST00000176265.1
ENSMUST00000154079.1
S-adenosylhomocysteine hydrolase-like 2
chr17_-_83631892 1.06 ENSMUST00000051482.1
potassium voltage-gated channel, subfamily G, member 3
chr3_-_96220880 1.06 ENSMUST00000090782.3
histone cluster 2, H2ac
chr6_+_71199827 1.06 ENSMUST00000067492.7
fatty acid binding protein 1, liver
chr11_-_82871133 1.06 ENSMUST00000071152.7
ENSMUST00000108173.3
ring finger and FYVE like domain containing protein
chr11_+_31872100 1.05 ENSMUST00000020543.6
ENSMUST00000109412.2
cytoplasmic polyadenylation element binding protein 4
chr8_+_71464910 1.04 ENSMUST00000048914.6
mitochondrial ribosomal protein L34
chr4_+_156215920 1.04 ENSMUST00000105572.1
RIKEN cDNA 2310042D19 gene
chr5_+_118065360 1.03 ENSMUST00000031305.3
predicted gene 9754
chr8_-_94838255 1.03 ENSMUST00000161762.1
ENSMUST00000162538.1
cytokine induced apoptosis inhibitor 1
chr10_+_80805233 1.01 ENSMUST00000036016.4
anti-Mullerian hormone
chr1_+_91250482 1.01 ENSMUST00000171112.1
ubiquitin-conjugating enzyme E2F (putative)
chr9_+_119937606 1.01 ENSMUST00000035100.5
tetratricopeptide repeat domain 21A
chr19_+_21272276 1.00 ENSMUST00000025659.4
zinc finger, AN1-type domain 5
chr11_+_54304005 1.00 ENSMUST00000000145.5
ENSMUST00000138515.1
acyl-CoA synthetase long-chain family member 6
chr7_-_110769345 1.00 ENSMUST00000098108.2
RIKEN cDNA B430319F04 gene
chr7_-_98145472 0.98 ENSMUST00000098281.2
olfactory marker protein
chr10_-_43540945 0.98 ENSMUST00000147196.1
ENSMUST00000019932.3
RIKEN cDNA 1700021F05 gene
chr2_+_103970115 0.97 ENSMUST00000111143.1
ENSMUST00000138815.1
LIM domain only 2
chr13_+_23746734 0.97 ENSMUST00000099703.2
histone cluster 1, H2bb
chr8_+_94152607 0.97 ENSMUST00000034211.8
metallothionein 3
chr16_+_35770382 0.96 ENSMUST00000023555.4
Hspb associated protein 1
chr10_+_118860826 0.96 ENSMUST00000059966.4
RIKEN cDNA 4932442E05 gene
chr2_+_30416096 0.95 ENSMUST00000113601.3
ENSMUST00000113603.3
protein phosphatase 2A, regulatory subunit B (PR 53)
chr7_+_17150210 0.94 ENSMUST00000108491.1
ENSMUST00000065540.5
carcinoembryonic antigen-related cell adhesion molecule 3
chr2_+_30416031 0.94 ENSMUST00000042055.3
protein phosphatase 2A, regulatory subunit B (PR 53)
chr17_-_34804546 0.93 ENSMUST00000025223.8
cytochrome P450, family 21, subfamily a, polypeptide 1
chr2_+_103970221 0.93 ENSMUST00000111140.2
ENSMUST00000111139.2
LIM domain only 2
chr13_-_22042949 0.92 ENSMUST00000091741.4
histone cluster 1, H2ag
chr15_-_44428303 0.92 ENSMUST00000038719.6
NudC domain containing 1
chr8_-_70523085 0.92 ENSMUST00000137610.1
ENSMUST00000121623.1
ENSMUST00000093456.5
ENSMUST00000118850.1
KxDL motif containing 1
chr4_-_73950834 0.92 ENSMUST00000095023.1
ENSMUST00000030101.3
RIKEN cDNA 2310002L09 gene
chr3_-_84040151 0.92 ENSMUST00000052342.7
RIKEN cDNA D930015E06 gene
chr2_+_32587057 0.91 ENSMUST00000102818.4
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr7_+_4740111 0.91 ENSMUST00000098853.2
suppressor of variegation 4-20 homolog 2 (Drosophila)
chr3_-_86920830 0.90 ENSMUST00000029719.8
doublecortin-like kinase 2
chr13_-_74350206 0.90 ENSMUST00000022062.7
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr17_-_45474839 0.90 ENSMUST00000024731.8
spermatogenesis associated, serine-rich 1
chr7_-_141429351 0.89 ENSMUST00000164387.1
ENSMUST00000137488.1
ENSMUST00000084436.3
cell cycle exit and neuronal differentiation 1
chr13_+_55445301 0.89 ENSMUST00000001115.8
ENSMUST00000099482.3
G protein-coupled receptor kinase 6
chr10_+_14523062 0.89 ENSMUST00000096020.5
predicted gene 10335
chr4_-_45108038 0.88 ENSMUST00000107809.2
ENSMUST00000107808.2
ENSMUST00000107807.1
ENSMUST00000107810.2
translocase of outer mitochondrial membrane 5 homolog (yeast)
chr9_+_109832749 0.88 ENSMUST00000147777.1
ENSMUST00000035053.5
ENSMUST00000133483.1
NME/NM23 nucleoside diphosphate kinase 6
chr2_+_130576170 0.88 ENSMUST00000028764.5
oxytocin
chr9_+_109832998 0.87 ENSMUST00000119376.1
ENSMUST00000122343.1
NME/NM23 nucleoside diphosphate kinase 6
chr11_-_120630516 0.86 ENSMUST00000106181.1
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr4_-_83324135 0.86 ENSMUST00000030205.7
tetratricopeptide repeat domain 39B
chrX_+_160768013 0.86 ENSMUST00000033650.7
retinoschisis (X-linked, juvenile) 1 (human)
chr8_-_70120816 0.86 ENSMUST00000002412.8
neurocan
chr2_+_178118975 0.85 ENSMUST00000108917.1
phosphatase and actin regulator 3
chr2_+_137663424 0.85 ENSMUST00000134833.1
predicted gene 14064
chr4_-_137409777 0.84 ENSMUST00000024200.6
predicted gene 13011
chr15_-_98728120 0.83 ENSMUST00000003445.6
FK506 binding protein 11
chr7_+_78783119 0.83 ENSMUST00000032840.4
mitochondrial ribosomal protein S11
chr19_+_5878622 0.83 ENSMUST00000136833.1
ENSMUST00000141362.1
solute carrier family 25, member 45
chr15_-_102516806 0.83 ENSMUST00000169162.1
ENSMUST00000023812.2
ENSMUST00000165174.1
ENSMUST00000169367.1
ENSMUST00000169377.1
mitogen-activated protein kinase kinase kinase 12
chr7_-_105574324 0.82 ENSMUST00000081165.7
amyloid beta (A4) precursor protein-binding, family B, member 1
chr19_-_6996025 0.81 ENSMUST00000041686.3
ENSMUST00000180765.1
nudix (nucleoside diphosphate linked moiety X)-type motif 22
chr15_-_98221056 0.80 ENSMUST00000170618.1
ENSMUST00000141911.1
olfactory receptor 287
chr2_-_73911323 0.80 ENSMUST00000111996.1
ENSMUST00000018914.2
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)
chr14_+_20929416 0.80 ENSMUST00000022369.7
vinculin
chr10_-_62507737 0.79 ENSMUST00000020271.6
serglycin
chr1_+_135799833 0.79 ENSMUST00000148201.1
troponin I, skeletal, slow 1
chr11_+_67586520 0.78 ENSMUST00000108682.2
growth arrest specific 7
chr11_+_90638127 0.77 ENSMUST00000020851.8
cytochrome c oxidase assembly protein 11
chr7_+_142434977 0.77 ENSMUST00000118276.1
ENSMUST00000105976.1
ENSMUST00000097939.2
synaptotagmin VIII
chr10_+_128083273 0.76 ENSMUST00000026459.5
ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit
chr15_-_52478228 0.75 ENSMUST00000081993.1
predicted pseudogene 10020
chr18_+_77938452 0.75 ENSMUST00000044622.5
ectopic P-granules autophagy protein 5 homolog (C. elegans)
chr4_+_107830958 0.75 ENSMUST00000106731.2
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr2_+_152105722 0.75 ENSMUST00000099225.2
sulfiredoxin 1 homolog (S. cerevisiae)
chr1_+_36691487 0.75 ENSMUST00000081180.4
cytochrome c oxidase subunit Vb
chr19_-_7217549 0.74 ENSMUST00000039758.4
cytochrome c oxidase subunit VIIIa
chr7_+_4740178 0.74 ENSMUST00000108583.2
suppressor of variegation 4-20 homolog 2 (Drosophila)
chr13_+_113209659 0.74 ENSMUST00000038144.8
endothelial cell-specific molecule 1
chr2_+_160888101 0.74 ENSMUST00000109455.2
ENSMUST00000040872.6
lipin 3
chr12_+_102554966 0.74 ENSMUST00000021610.5
chromogranin A
chr12_+_12911986 0.73 ENSMUST00000085720.1
ribosomal protein L36, pseudogene 3
chr8_-_84969740 0.73 ENSMUST00000109736.2
ENSMUST00000140561.1
ribonuclease H2, large subunit
chr7_+_100006404 0.72 ENSMUST00000032977.4
chordin-like 2
chr1_-_136131171 0.72 ENSMUST00000146091.3
ENSMUST00000165464.1
ENSMUST00000166747.1
ENSMUST00000134998.1
predicted gene 15850
chr10_-_80855187 0.72 ENSMUST00000035775.8
LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr11_-_33276334 0.71 ENSMUST00000183831.1
predicted gene 12117
chr8_+_105701624 0.71 ENSMUST00000093195.6
par-6 (partitioning defective 6,) homolog alpha (C. elegans)
chr7_+_4740137 0.70 ENSMUST00000130215.1
ENSMUST00000108582.3
suppressor of variegation 4-20 homolog 2 (Drosophila)
chr2_-_103073335 0.70 ENSMUST00000132449.1
ENSMUST00000111183.1
ENSMUST00000011058.2
pyruvate dehydrogenase complex, component X
chr8_+_120668308 0.69 ENSMUST00000181795.1
cytochrome c oxidase subunit IV isoform 1
chr15_+_74563738 0.69 ENSMUST00000170845.1
brain-specific angiogenesis inhibitor 1
chr13_+_21716385 0.69 ENSMUST00000070124.3
histone cluster 1, H2ai
chr15_-_82764176 0.68 ENSMUST00000055721.4
cytochrome P450, family 2, subfamily d, polypeptide 40
chr10_-_62527413 0.68 ENSMUST00000160643.1
serglycin
chr2_+_160888156 0.68 ENSMUST00000109457.2
lipin 3
chr10_-_62508097 0.68 ENSMUST00000159020.1
serglycin
chr7_+_100494044 0.67 ENSMUST00000153287.1
uncoupling protein 2 (mitochondrial, proton carrier)
chr11_+_67586675 0.67 ENSMUST00000108680.1
growth arrest specific 7
chr11_+_101078411 0.66 ENSMUST00000019445.5
hydroxysteroid (17-beta) dehydrogenase 1
chr7_+_100493795 0.66 ENSMUST00000129324.1
uncoupling protein 2 (mitochondrial, proton carrier)
chr11_-_5065276 0.66 ENSMUST00000109895.1
ENSMUST00000152257.1
ENSMUST00000037146.3
ENSMUST00000056649.6
growth arrest-specific 2 like 1
chr2_+_140170641 0.65 ENSMUST00000044825.4
NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
chr9_-_77347816 0.65 ENSMUST00000184138.1
ENSMUST00000184006.1
ENSMUST00000185144.1
ENSMUST00000034910.9
muscular LMNA-interacting protein
chr2_+_25262589 0.65 ENSMUST00000114336.3
taperin
chr1_-_51941261 0.65 ENSMUST00000097103.3
predicted gene 8420
chr1_+_63176818 0.65 ENSMUST00000129339.1
eukaryotic translation elongation factor 1 beta 2
chr9_+_57910974 0.63 ENSMUST00000163329.1
ubiquitin-like 7 (bone marrow stromal cell-derived)
chr13_+_51100810 0.62 ENSMUST00000095797.5
spindlin 1
chr12_-_111966954 0.62 ENSMUST00000021719.5
RIKEN cDNA 2010107E04 gene
chr9_-_77347787 0.62 ENSMUST00000184848.1
ENSMUST00000184415.1
muscular LMNA-interacting protein
chr18_+_37955544 0.61 ENSMUST00000070709.2
ENSMUST00000177058.1
ENSMUST00000169360.2
ENSMUST00000163591.2
ENSMUST00000091932.5
RELT-like 2
chr5_-_66151903 0.60 ENSMUST00000167950.1
RNA binding motif protein 47
chr11_+_53720790 0.60 ENSMUST00000048605.2
interleukin 5
chr4_-_83324239 0.60 ENSMUST00000048274.4
ENSMUST00000102823.3
tetratricopeptide repeat domain 39B
chr19_-_47090610 0.60 ENSMUST00000096014.3
upregulated during skeletal muscle growth 5
chr1_-_4785671 0.59 ENSMUST00000130201.1
ENSMUST00000156816.1
mitochondrial ribosomal protein L15
chr16_+_10545339 0.59 ENSMUST00000066345.7
ENSMUST00000115824.3
ENSMUST00000155633.1
C-type lectin domain family 16, member A
chr10_-_75517324 0.59 ENSMUST00000039796.7
guanylyl cyclase domain containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr5a2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 11.6 GO:0008355 olfactory learning(GO:0008355)
1.2 3.5 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
1.1 12.2 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.9 3.8 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.7 2.7 GO:0033367 protein localization to secretory granule(GO:0033366) protein localization to mast cell secretory granule(GO:0033367) protease localization to mast cell secretory granule(GO:0033368) maintenance of protein location in mast cell secretory granule(GO:0033370) T cell secretory granule organization(GO:0033371) maintenance of protease location in mast cell secretory granule(GO:0033373) protein localization to T cell secretory granule(GO:0033374) protease localization to T cell secretory granule(GO:0033375) maintenance of protein location in T cell secretory granule(GO:0033377) maintenance of protease location in T cell secretory granule(GO:0033379) granzyme B localization to T cell secretory granule(GO:0033380) maintenance of granzyme B location in T cell secretory granule(GO:0033382)
0.7 2.0 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.5 6.0 GO:0002536 respiratory burst involved in inflammatory response(GO:0002536)
0.5 1.9 GO:0015744 succinate transport(GO:0015744)
0.5 1.4 GO:0098971 anterograde dendritic transport of neurotransmitter receptor complex(GO:0098971)
0.4 1.3 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.4 1.3 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.4 1.3 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933)
0.4 2.6 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.4 1.7 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.3 1.2 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.3 0.9 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.3 1.2 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.3 1.5 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.3 1.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.3 1.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.3 1.3 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.3 1.3 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.2 1.2 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.2 1.2 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.2 1.9 GO:0009249 protein lipoylation(GO:0009249)
0.2 0.7 GO:0019043 establishment of viral latency(GO:0019043)
0.2 1.2 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.2 0.7 GO:0097212 lysosomal membrane organization(GO:0097212)
0.2 0.9 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.2 1.3 GO:0061622 glycolytic process through glucose-1-phosphate(GO:0061622)
0.2 0.6 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.2 2.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 2.6 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.2 2.0 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.2 0.8 GO:0046133 pyrimidine ribonucleoside catabolic process(GO:0046133)
0.2 1.0 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.2 1.2 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.2 0.5 GO:0021530 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.2 1.3 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.2 0.9 GO:0006705 mineralocorticoid biosynthetic process(GO:0006705)
0.1 1.7 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 1.1 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 1.3 GO:0032264 IMP salvage(GO:0032264)
0.1 0.4 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.1 1.2 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 1.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.5 GO:0046684 response to pyrethroid(GO:0046684)
0.1 1.0 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 1.9 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.7 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.1 0.5 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.1 0.6 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.1 0.8 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.5 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.1 0.8 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.8 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.1 0.4 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.1 2.0 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.3 GO:0001980 regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980)
0.1 1.3 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 1.9 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.1 0.3 GO:0098976 excitatory chemical synaptic transmission(GO:0098976) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.1 0.4 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.4 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.1 0.3 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.1 0.3 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.1 0.4 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.1 0.7 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.1 1.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 0.6 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.8 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.1 2.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 9.9 GO:0006334 nucleosome assembly(GO:0006334)
0.1 0.5 GO:0044351 macropinocytosis(GO:0044351)
0.1 0.2 GO:0003134 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134) regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081)
0.1 0.7 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 0.5 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 1.3 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 0.5 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 0.2 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.1 0.3 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.1 0.2 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
0.1 0.5 GO:0007144 female meiosis I(GO:0007144)
0.1 1.0 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 2.4 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 1.4 GO:0055098 response to low-density lipoprotein particle(GO:0055098)
0.1 0.3 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1 0.2 GO:1902477 defense response, incompatible interaction(GO:0009814) defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.1 1.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.9 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.1 0.8 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 1.0 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 0.4 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.7 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 3.3 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 5.2 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.4 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 1.4 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.4 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.7 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.5 GO:0030007 cellular potassium ion homeostasis(GO:0030007)
0.0 0.3 GO:0051013 microtubule severing(GO:0051013)
0.0 0.3 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 1.0 GO:0045116 protein neddylation(GO:0045116)
0.0 0.9 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.3 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.0 0.6 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.5 GO:0042168 heme metabolic process(GO:0042168)
0.0 0.6 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 1.5 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.3 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.3 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.6 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.0 0.2 GO:0018094 protein polyglycylation(GO:0018094)
0.0 1.0 GO:0048745 smooth muscle tissue development(GO:0048745)
0.0 1.7 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.6 GO:0007143 female meiotic division(GO:0007143)
0.0 0.8 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.6 GO:0042775 mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.0 0.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.5 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 0.8 GO:0045739 positive regulation of DNA repair(GO:0045739)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.2 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.9 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 1.1 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.9 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 0.3 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.3 GO:0002827 positive regulation of T-helper 1 type immune response(GO:0002827)
0.0 0.1 GO:0006113 fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.0 0.9 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.7 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.1 GO:0043308 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.0 0.8 GO:0055010 ventricular cardiac muscle tissue morphogenesis(GO:0055010)
0.0 0.4 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 1.2 GO:0000422 mitophagy(GO:0000422) mitochondrion disassembly(GO:0061726)
0.0 0.4 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.6 GO:0006414 translational elongation(GO:0006414)
0.0 0.8 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.9 GO:0032418 lysosome localization(GO:0032418)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.0 0.2 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.2 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.0 0.1 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.2 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.5 GO:0007032 endosome organization(GO:0007032)
0.0 0.7 GO:0019369 arachidonic acid metabolic process(GO:0019369)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.2 GO:0097512 cardiac myofibril(GO:0097512)
0.3 1.3 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.3 1.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.2 2.7 GO:0042629 mast cell granule(GO:0042629)
0.2 1.4 GO:1990075 periciliary membrane compartment(GO:1990075)
0.2 1.2 GO:0097452 GAIT complex(GO:0097452)
0.2 0.8 GO:1990812 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.2 1.6 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.7 GO:0042583 chromaffin granule(GO:0042583)
0.1 11.5 GO:0000786 nucleosome(GO:0000786)
0.1 0.6 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 2.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 1.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 0.5 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1 3.0 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.1 0.4 GO:0042642 actomyosin, myosin complex part(GO:0042642)
0.1 0.7 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.7 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 0.6 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 0.6 GO:1990130 Iml1 complex(GO:1990130)
0.1 1.0 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.7 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 0.6 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.4 GO:0044393 microspike(GO:0044393)
0.1 2.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.5 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 1.1 GO:0072546 ER membrane protein complex(GO:0072546)
0.1 4.3 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.1 0.3 GO:0032280 symmetric synapse(GO:0032280)
0.1 1.1 GO:0045179 apical cortex(GO:0045179)
0.1 0.5 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.8 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.8 GO:0005861 troponin complex(GO:0005861)
0.1 0.9 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.6 GO:0005687 U4 snRNP(GO:0005687)
0.0 1.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.8 GO:0005916 fascia adherens(GO:0005916)
0.0 2.4 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.4 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 1.2 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.5 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 1.3 GO:0002102 podosome(GO:0002102)
0.0 7.0 GO:0043209 myelin sheath(GO:0043209)
0.0 0.6 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.4 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.7 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.1 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.2 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.4 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 1.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.5 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.6 GO:0016605 PML body(GO:0016605)
0.0 1.8 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.8 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.5 GO:0051233 spindle midzone(GO:0051233)
0.0 2.4 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 2.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.8 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.4 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.2 GO:0046930 pore complex(GO:0046930)
0.0 0.5 GO:0001917 photoreceptor inner segment(GO:0001917)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 11.6 GO:0005186 pheromone activity(GO:0005186)
0.7 7.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.6 1.9 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.5 2.0 GO:0070052 collagen V binding(GO:0070052)
0.4 1.3 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.4 2.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.4 1.2 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.3 1.3 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.3 1.3 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.3 2.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.3 1.7 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.3 1.7 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.2 0.7 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.2 0.9 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.2 1.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.2 0.7 GO:0070401 NADP+ binding(GO:0070401)
0.2 1.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 0.8 GO:0038025 reelin receptor activity(GO:0038025)
0.2 4.8 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 0.8 GO:0043532 angiostatin binding(GO:0043532)
0.2 0.8 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.2 1.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 1.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 1.3 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 2.1 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 0.4 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.1 5.5 GO:0009055 electron carrier activity(GO:0009055)
0.1 5.5 GO:0008009 chemokine activity(GO:0008009)
0.1 2.4 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 1.0 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 2.9 GO:0008171 O-methyltransferase activity(GO:0008171)
0.1 0.6 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.1 1.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 1.6 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.7 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.9 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.7 GO:0015288 porin activity(GO:0015288)
0.1 0.5 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.5 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.6 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.8 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.4 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 0.3 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 1.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.2 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.8 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.4 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.1 0.8 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.5 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 0.3 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 0.6 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 1.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.2 GO:0070736 protein-glycine ligase activity, initiating(GO:0070736)
0.1 1.0 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.8 GO:0002162 dystroglycan binding(GO:0002162) alpha-catenin binding(GO:0045294)
0.0 0.5 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.2 GO:0001639 PLC activating G-protein coupled glutamate receptor activity(GO:0001639) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.0 1.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 2.0 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0030172 troponin C binding(GO:0030172)
0.0 2.4 GO:0070888 E-box binding(GO:0070888)
0.0 1.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.3 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.0 0.3 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.1 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.0 0.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.0 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.8 GO:0048156 tau protein binding(GO:0048156)
0.0 0.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.3 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 1.3 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.7 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 6.2 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.5 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.4 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.9 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.0 3.4 GO:0008083 growth factor activity(GO:0008083)
0.0 2.6 GO:0003774 motor activity(GO:0003774)
0.0 0.4 GO:0016208 AMP binding(GO:0016208)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 2.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 1.3 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.8 PID RAS PATHWAY Regulation of Ras family activation
0.1 3.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.0 PID ALK2 PATHWAY ALK2 signaling events
0.1 2.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 0.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.9 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.0 PID ARF 3PATHWAY Arf1 pathway
0.0 1.4 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.8 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.6 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.4 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 1.0 PID FOXO PATHWAY FoxO family signaling
0.0 6.0 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.1 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.7 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.8 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.3 10.7 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.2 5.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 2.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 2.0 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 11.0 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.1 1.7 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 0.7 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 1.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 0.9 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 2.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 2.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.8 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.6 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.7 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 1.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.8 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 1.9 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.5 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 1.0 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.6 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 1.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.0 REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION Genes involved in Cleavage of Growing Transcript in the Termination Region
0.0 0.3 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 1.1 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.3 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 2.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.7 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters