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GSE58827: Dynamics of the Mouse Liver

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Results for Nanog

Z-value: 1.32

Motif logo

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Transcription factors associated with Nanog

Gene Symbol Gene ID Gene Info
Nanog
ENSMUSG00000012396.6 Nanog homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nanogmm10_v2_chr6_+_122707489_1227076080.173.2e-01Click!

Activity profile of Nanog motif

Sorted Z-values of Nanog motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_41458923 10.52 ENSMUST00000031910.7
Prss1
protease, serine, 1 (trypsin 1)
chr19_-_11640828 10.49 ENSMUST00000112984.2
Ms4a3
membrane-spanning 4-domains, subfamily A, member 3
chr6_+_41392356 8.62 ENSMUST00000049079.7
Gm5771
predicted gene 5771
chr7_-_142679533 7.48 ENSMUST00000162317.1
ENSMUST00000125933.1
ENSMUST00000105931.1
ENSMUST00000105930.1
ENSMUST00000105933.1
ENSMUST00000105932.1
ENSMUST00000000220.2
Ins2
insulin II
chr2_+_128591205 7.07 ENSMUST00000155430.1
Gm355
predicted gene 355
chr17_+_29135056 7.06 ENSMUST00000087942.4
Rab44
RAB44, member RAS oncogene family
chr9_+_65890237 6.42 ENSMUST00000045802.6
2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr6_+_41354105 6.06 ENSMUST00000072103.5
Try10
trypsin 10
chr17_+_40811089 5.57 ENSMUST00000024721.7
Rhag
Rhesus blood group-associated A glycoprotein
chr1_-_75133866 5.54 ENSMUST00000027405.4
Slc23a3
solute carrier family 23 (nucleobase transporters), member 3
chr14_+_27000362 5.24 ENSMUST00000035433.8
Hesx1
homeobox gene expressed in ES cells
chr12_+_109549157 5.21 ENSMUST00000128458.1
ENSMUST00000150851.1
Meg3
maternally expressed 3
chr9_-_123678782 4.94 ENSMUST00000170591.1
ENSMUST00000171647.1
Slc6a20a
solute carrier family 6 (neurotransmitter transporter), member 20A
chrX_+_8271133 4.89 ENSMUST00000127103.1
ENSMUST00000115591.1
Slc38a5
solute carrier family 38, member 5
chr2_+_164948219 4.87 ENSMUST00000017881.2
Mmp9
matrix metallopeptidase 9
chrX_+_8271381 4.75 ENSMUST00000033512.4
Slc38a5
solute carrier family 38, member 5
chr7_-_6730412 4.72 ENSMUST00000051209.4
Peg3
paternally expressed 3
chr18_+_36528145 4.68 ENSMUST00000074298.6
ENSMUST00000115694.2
Slc4a9
solute carrier family 4, sodium bicarbonate cotransporter, member 9
chr3_+_105870858 4.41 ENSMUST00000164730.1
Adora3
adenosine A3 receptor
chr6_+_41302265 4.17 ENSMUST00000031913.4
Try4
trypsin 4
chr5_+_33658123 4.00 ENSMUST00000074849.6
ENSMUST00000079534.4
Tacc3
transforming, acidic coiled-coil containing protein 3
chrX_+_8271642 3.83 ENSMUST00000115590.1
Slc38a5
solute carrier family 38, member 5
chr9_-_123678873 3.64 ENSMUST00000040960.6
Slc6a20a
solute carrier family 6 (neurotransmitter transporter), member 20A
chr3_+_114030532 3.58 ENSMUST00000123619.1
ENSMUST00000092155.5
Col11a1
collagen, type XI, alpha 1
chr10_+_58394361 3.55 ENSMUST00000020077.4
Lims1
LIM and senescent cell antigen-like domains 1
chr7_+_79660196 3.48 ENSMUST00000035977.7
Ticrr
TOPBP1-interacting checkpoint and replication regulator
chr12_-_69790660 3.39 ENSMUST00000021377.4
Cdkl1
cyclin-dependent kinase-like 1 (CDC2-related kinase)
chr16_-_18622403 3.38 ENSMUST00000167388.1
Gp1bb
glycoprotein Ib, beta polypeptide
chr15_+_80097866 3.37 ENSMUST00000143928.1
Syngr1
synaptogyrin 1
chr5_+_33658567 3.36 ENSMUST00000114426.3
Tacc3
transforming, acidic coiled-coil containing protein 3
chr3_-_54915867 3.33 ENSMUST00000070342.3
Sertm1
serine rich and transmembrane domain containing 1
chr3_+_88081997 3.32 ENSMUST00000071812.5
Iqgap3
IQ motif containing GTPase activating protein 3
chr5_+_33658550 3.32 ENSMUST00000152847.1
Tacc3
transforming, acidic coiled-coil containing protein 3
chr15_-_103251465 3.23 ENSMUST00000133600.1
ENSMUST00000134554.1
ENSMUST00000156927.1
ENSMUST00000149111.1
ENSMUST00000132836.1
Nfe2
nuclear factor, erythroid derived 2
chr10_+_58394381 3.23 ENSMUST00000105468.1
Lims1
LIM and senescent cell antigen-like domains 1
chr3_+_105870898 3.09 ENSMUST00000010279.5
Adora3
adenosine A3 receptor
chr7_-_14254870 2.97 ENSMUST00000184731.1
ENSMUST00000076576.6
Sult2a6
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 6
chr19_-_9899450 2.94 ENSMUST00000025562.7
Incenp
inner centromere protein
chr7_-_14123042 2.82 ENSMUST00000098809.2
Sult2a3
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 3
chr4_-_49597425 2.73 ENSMUST00000150664.1
Tmem246
transmembrane protein 246
chr9_-_20959785 2.71 ENSMUST00000177754.1
Dnmt1
DNA methyltransferase (cytosine-5) 1
chr3_+_68869563 2.70 ENSMUST00000054551.2
1110032F04Rik
RIKEN cDNA 1110032F04 gene
chrX_+_134308084 2.66 ENSMUST00000081064.5
ENSMUST00000101251.1
ENSMUST00000129782.1
Cenpi
centromere protein I
chr11_+_44617310 2.55 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
Ebf1
early B cell factor 1
chr11_+_62248977 2.54 ENSMUST00000018644.2
Adora2b
adenosine A2b receptor
chr6_+_124829582 2.45 ENSMUST00000024270.7
Cdca3
cell division cycle associated 3
chr12_+_102128718 2.40 ENSMUST00000159329.1
Slc24a4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr15_+_44457522 2.40 ENSMUST00000166957.1
ENSMUST00000038336.5
Pkhd1l1
polycystic kidney and hepatic disease 1-like 1
chr7_+_19411086 2.39 ENSMUST00000003643.1
Ckm
creatine kinase, muscle
chr6_-_136781718 2.37 ENSMUST00000078095.6
ENSMUST00000032338.7
Gucy2c
guanylate cyclase 2c
chr18_-_21652362 2.32 ENSMUST00000049105.4
Klhl14
kelch-like 14
chr12_+_109747903 2.31 ENSMUST00000183084.1
ENSMUST00000182300.1
Mirg
miRNA containing gene
chr6_-_145047725 2.25 ENSMUST00000123930.1
Bcat1
branched chain aminotransferase 1, cytosolic
chr6_-_67037399 2.24 ENSMUST00000043098.6
Gadd45a
growth arrest and DNA-damage-inducible 45 alpha
chr2_-_116067391 2.23 ENSMUST00000140185.1
2700033N17Rik
RIKEN cDNA 2700033N17 gene
chr7_-_100467149 2.20 ENSMUST00000184420.1
RP23-308M1.2
RP23-308M1.2
chr15_-_66831625 2.19 ENSMUST00000164163.1
Sla
src-like adaptor
chr7_-_133702515 2.19 ENSMUST00000153698.1
Uros
uroporphyrinogen III synthase
chr3_+_122044428 2.16 ENSMUST00000013995.8
Abca4
ATP-binding cassette, sub-family A (ABC1), member 4
chr6_+_124829540 2.12 ENSMUST00000150120.1
Cdca3
cell division cycle associated 3
chrX_-_164250368 2.12 ENSMUST00000112263.1
Bmx
BMX non-receptor tyrosine kinase
chr11_-_116077606 2.11 ENSMUST00000106450.1
Unc13d
unc-13 homolog D (C. elegans)
chr3_-_144760841 2.10 ENSMUST00000059091.5
Clca1
chloride channel calcium activated 1
chr17_-_25727364 2.08 ENSMUST00000170070.1
ENSMUST00000048054.7
Chtf18
CTF18, chromosome transmission fidelity factor 18
chr13_-_89742244 2.07 ENSMUST00000109543.2
ENSMUST00000159337.1
ENSMUST00000159910.1
ENSMUST00000109544.2
Vcan
versican
chr12_-_91384403 2.06 ENSMUST00000141429.1
Cep128
centrosomal protein 128
chr3_+_37312514 2.03 ENSMUST00000057975.7
ENSMUST00000108121.3
Bbs12
Bardet-Biedl syndrome 12 (human)
chr4_+_154960915 2.01 ENSMUST00000049621.6
Hes5
hairy and enhancer of split 5 (Drosophila)
chr15_-_51991679 2.01 ENSMUST00000022927.9
Rad21
RAD21 homolog (S. pombe)
chr3_-_116253467 1.99 ENSMUST00000090473.5
Gpr88
G-protein coupled receptor 88
chr18_+_82554463 1.90 ENSMUST00000062446.7
ENSMUST00000102812.4
ENSMUST00000075372.5
ENSMUST00000080658.4
ENSMUST00000152071.1
ENSMUST00000114674.3
ENSMUST00000142850.1
ENSMUST00000133193.1
ENSMUST00000123251.1
ENSMUST00000153478.1
ENSMUST00000132369.1
Mbp
myelin basic protein
chr10_+_130322845 1.87 ENSMUST00000042586.8
Tespa1
thymocyte expressed, positive selection associated 1
chr17_-_81649607 1.86 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
Slc8a1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr6_-_102464667 1.86 ENSMUST00000032159.6
Cntn3
contactin 3
chr11_+_115154139 1.83 ENSMUST00000021076.5
Rab37
RAB37, member of RAS oncogene family
chr3_+_105904377 1.81 ENSMUST00000000574.1
Adora3
adenosine A3 receptor
chr9_-_15357692 1.80 ENSMUST00000098979.3
ENSMUST00000161132.1
5830418K08Rik
RIKEN cDNA 5830418K08 gene
chr7_-_115846080 1.76 ENSMUST00000166207.1
Sox6
SRY-box containing gene 6
chr15_+_9436028 1.74 ENSMUST00000042360.3
Capsl
calcyphosine-like
chr3_-_107239707 1.66 ENSMUST00000049852.8
Prok1
prokineticin 1
chr6_-_50456085 1.64 ENSMUST00000146341.1
ENSMUST00000071728.4
Osbpl3
oxysterol binding protein-like 3
chr13_-_19732929 1.60 ENSMUST00000151029.1
A530099J19Rik
RIKEN cDNA A530099J19 gene
chr6_-_136922169 1.56 ENSMUST00000032343.6
Erp27
endoplasmic reticulum protein 27
chr13_-_89742490 1.55 ENSMUST00000109546.2
Vcan
versican
chr12_-_83487708 1.54 ENSMUST00000177959.1
ENSMUST00000178756.1
Dpf3
D4, zinc and double PHD fingers, family 3
chr11_+_62820469 1.54 ENSMUST00000108703.1
Trim16
tripartite motif-containing 16
chr7_+_43437073 1.53 ENSMUST00000070518.2
Nkg7
natural killer cell group 7 sequence
chr17_-_51826562 1.51 ENSMUST00000024720.4
ENSMUST00000129667.1
ENSMUST00000156051.1
ENSMUST00000169480.1
ENSMUST00000148559.1
Satb1
special AT-rich sequence binding protein 1
chr4_+_12906838 1.51 ENSMUST00000143186.1
ENSMUST00000183345.1
Triqk
triple QxxK/R motif containing
chrX_+_48146436 1.49 ENSMUST00000033427.6
Sash3
SAM and SH3 domain containing 3
chr4_+_126024506 1.46 ENSMUST00000106162.1
Csf3r
colony stimulating factor 3 receptor (granulocyte)
chr14_-_49245389 1.45 ENSMUST00000130853.1
ENSMUST00000022398.7
1700011H14Rik
RIKEN cDNA 1700011H14 gene
chr17_-_47834682 1.44 ENSMUST00000066368.6
Mdfi
MyoD family inhibitor
chr5_-_138172383 1.40 ENSMUST00000000505.9
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chrX_+_49470450 1.39 ENSMUST00000114904.3
Arhgap36
Rho GTPase activating protein 36
chr13_+_44729794 1.38 ENSMUST00000172830.1
Jarid2
jumonji, AT rich interactive domain 2
chr16_+_44765732 1.38 ENSMUST00000057488.8
Cd200r1
CD200 receptor 1
chr4_+_43506966 1.38 ENSMUST00000030183.3
Car9
carbonic anhydrase 9
chr7_+_28693032 1.36 ENSMUST00000151227.1
ENSMUST00000108281.1
Fbxo27
F-box protein 27
chr1_-_87101590 1.36 ENSMUST00000113270.2
Alpi
alkaline phosphatase, intestinal
chr16_+_19760902 1.35 ENSMUST00000119468.1
B3gnt5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr12_+_69790288 1.34 ENSMUST00000021378.3
4930512B01Rik
RIKEN cDNA 4930512B01 gene
chr7_-_141655319 1.33 ENSMUST00000062451.7
Muc6
mucin 6, gastric
chr3_+_103860265 1.33 ENSMUST00000029433.7
Ptpn22
protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr6_-_145047636 1.33 ENSMUST00000149769.1
Bcat1
branched chain aminotransferase 1, cytosolic
chrX_+_49470555 1.31 ENSMUST00000042444.6
Arhgap36
Rho GTPase activating protein 36
chr4_+_101507947 1.30 ENSMUST00000149047.1
ENSMUST00000106929.3
Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr17_-_43543639 1.30 ENSMUST00000178772.1
Ankrd66
ankyrin repeat domain 66
chr6_+_125552948 1.30 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf
Von Willebrand factor homolog
chr13_-_47106176 1.29 ENSMUST00000021807.6
ENSMUST00000135278.1
Dek
DEK oncogene (DNA binding)
chr17_+_35841668 1.28 ENSMUST00000174124.1
Mdc1
mediator of DNA damage checkpoint 1
chr18_+_35553401 1.26 ENSMUST00000181664.1
Snhg4
small nucleolar RNA host gene 4 (non-protein coding)
chr3_-_37312418 1.26 ENSMUST00000075537.6
ENSMUST00000071400.6
ENSMUST00000102955.4
ENSMUST00000140956.1
Cetn4
centrin 4
chr2_+_57997884 1.26 ENSMUST00000112616.1
ENSMUST00000166729.1
Galnt5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5
chr13_-_12258093 1.25 ENSMUST00000099856.4
Mtr
5-methyltetrahydrofolate-homocysteine methyltransferase
chr7_-_45694369 1.25 ENSMUST00000040636.6
Sec1
secretory blood group 1
chr4_-_149454971 1.25 ENSMUST00000030848.2
Rbp7
retinol binding protein 7, cellular
chr11_-_20332689 1.24 ENSMUST00000109594.1
Slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr5_+_25246775 1.23 ENSMUST00000144971.1
Galnt11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11
chr18_-_15063560 1.23 ENSMUST00000168989.1
Kctd1
potassium channel tetramerisation domain containing 1
chr3_-_49757257 1.22 ENSMUST00000035931.7
Pcdh18
protocadherin 18
chr15_-_93519499 1.20 ENSMUST00000109255.2
Prickle1
prickle homolog 1 (Drosophila)
chr11_-_20332654 1.19 ENSMUST00000004634.6
Slc1a4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr5_+_30711849 1.18 ENSMUST00000088081.4
ENSMUST00000101442.3
Dpysl5
dihydropyrimidinase-like 5
chr6_+_125145235 1.17 ENSMUST00000119527.1
ENSMUST00000088276.6
ENSMUST00000051171.7
ENSMUST00000117675.1
Iffo1
intermediate filament family orphan 1
chr2_-_45112890 1.14 ENSMUST00000076836.6
Zeb2
zinc finger E-box binding homeobox 2
chr13_-_51567084 1.13 ENSMUST00000021898.5
Shc3
src homology 2 domain-containing transforming protein C3
chr2_+_125152505 1.13 ENSMUST00000110494.2
ENSMUST00000028630.2
ENSMUST00000110495.2
Slc12a1
solute carrier family 12, member 1
chr3_-_144819494 1.12 ENSMUST00000029929.7
Clca2
chloride channel calcium activated 2
chr17_+_8849974 1.10 ENSMUST00000115720.1
Pde10a
phosphodiesterase 10A
chr19_+_8802486 1.09 ENSMUST00000172175.1
Zbtb3
zinc finger and BTB domain containing 3
chr4_-_43046196 1.08 ENSMUST00000036462.5
Fam214b
family with sequence similarity 214, member B
chr13_-_19619820 1.08 ENSMUST00000002885.6
Epdr1
ependymin related protein 1 (zebrafish)
chr3_+_79884576 1.08 ENSMUST00000145992.1
Fam198b
family with sequence similarity 198, member B
chr5_-_16731074 1.07 ENSMUST00000073014.5
Gm8991
predicted pseudogene 8991
chr10_-_127351753 1.07 ENSMUST00000059718.4
Inhbe
inhibin beta E
chr3_+_10088173 1.05 ENSMUST00000061419.7
Gm9833
predicted gene 9833
chrX_+_159840463 1.04 ENSMUST00000112451.1
ENSMUST00000112453.2
Sh3kbp1
SH3-domain kinase binding protein 1
chr11_-_101095367 1.04 ENSMUST00000019447.8
Psmc3ip
proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein
chr1_+_172555932 1.03 ENSMUST00000061835.3
Vsig8
V-set and immunoglobulin domain containing 8
chr12_+_72441852 1.03 ENSMUST00000162159.1
Lrrc9
leucine rich repeat containing 9
chr7_+_25267669 1.01 ENSMUST00000169266.1
Cic
capicua homolog (Drosophila)
chr19_-_32196393 0.98 ENSMUST00000151822.1
Sgms1
sphingomyelin synthase 1
chr2_+_130274437 0.97 ENSMUST00000141872.1
Nop56
NOP56 ribonucleoprotein
chr17_+_78491549 0.96 ENSMUST00000079363.4
Gm10093
predicted pseudogene 10093
chr10_+_33905015 0.96 ENSMUST00000169670.1
Rsph4a
radial spoke head 4 homolog A (Chlamydomonas)
chr4_-_83052229 0.95 ENSMUST00000107230.1
Frem1
Fras1 related extracellular matrix protein 1
chr9_-_44342332 0.94 ENSMUST00000097558.3
Hmbs
hydroxymethylbilane synthase
chr14_-_18270953 0.93 ENSMUST00000100799.2
ENSMUST00000079419.4
ENSMUST00000080281.7
Rpl15
ribosomal protein L15
chr3_-_82876483 0.93 ENSMUST00000048647.7
Rbm46
RNA binding motif protein 46
chr6_-_116716888 0.92 ENSMUST00000056623.6
Tmem72
transmembrane protein 72
chrX_+_7822289 0.92 ENSMUST00000009875.4
Kcnd1
potassium voltage-gated channel, Shal-related family, member 1
chr8_+_110721462 0.91 ENSMUST00000052457.8
Mtss1l
metastasis suppressor 1-like
chr11_-_98053415 0.91 ENSMUST00000017544.2
Stac2
SH3 and cysteine rich domain 2
chr15_-_13173607 0.91 ENSMUST00000036439.4
Cdh6
cadherin 6
chr7_-_116084635 0.91 ENSMUST00000111755.3
Gm4353
predicted gene 4353
chr15_-_34356421 0.90 ENSMUST00000179647.1
9430069I07Rik
RIKEN cDNA 9430069I07 gene
chr3_+_65666223 0.89 ENSMUST00000099075.2
ENSMUST00000107848.1
ENSMUST00000161794.1
Lekr1
leucine, glutamate and lysine rich 1
chr2_+_127909058 0.89 ENSMUST00000110344.1
Acoxl
acyl-Coenzyme A oxidase-like
chr18_+_37518341 0.89 ENSMUST00000097609.1
Pcdhb22
protocadherin beta 22
chr5_-_99978914 0.89 ENSMUST00000112939.3
ENSMUST00000171786.1
ENSMUST00000072750.6
ENSMUST00000019128.8
ENSMUST00000172361.1
Hnrnpd
heterogeneous nuclear ribonucleoprotein D
chr4_+_101507855 0.87 ENSMUST00000038207.5
Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr1_-_172027251 0.85 ENSMUST00000138714.1
Vangl2
vang-like 2 (van gogh, Drosophila)
chr17_+_7170101 0.85 ENSMUST00000024575.6
Rps6ka2
ribosomal protein S6 kinase, polypeptide 2
chr6_-_142473075 0.85 ENSMUST00000032371.7
Gys2
glycogen synthase 2
chr3_-_55055038 0.84 ENSMUST00000029368.2
Ccna1
cyclin A1
chr7_+_113514085 0.81 ENSMUST00000122890.1
Far1
fatty acyl CoA reductase 1
chr16_+_20696175 0.80 ENSMUST00000128273.1
Fam131a
family with sequence similarity 131, member A
chr7_+_128246953 0.79 ENSMUST00000167965.1
Tgfb1i1
transforming growth factor beta 1 induced transcript 1
chr9_+_106368594 0.79 ENSMUST00000172306.2
Dusp7
dual specificity phosphatase 7
chr4_+_48585193 0.79 ENSMUST00000107703.1
Tmeff1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr11_-_40733373 0.78 ENSMUST00000020579.8
Hmmr
hyaluronan mediated motility receptor (RHAMM)
chr7_+_112742025 0.77 ENSMUST00000164363.1
Tead1
TEA domain family member 1
chr6_+_71909046 0.76 ENSMUST00000055296.8
Polr1a
polymerase (RNA) I polypeptide A
chr10_-_61476937 0.76 ENSMUST00000051330.4
D830039M14Rik
RIKEN cDNA D830039M14 gene
chr6_-_29179584 0.76 ENSMUST00000159200.1
Prrt4
proline-rich transmembrane protein 4
chr8_-_120589304 0.76 ENSMUST00000034278.5
Gins2
GINS complex subunit 2 (Psf2 homolog)
chr3_+_54481429 0.75 ENSMUST00000091130.3
Gm5641
predicted gene 5641
chr11_-_99244058 0.73 ENSMUST00000103132.3
ENSMUST00000038214.6
Krt222
keratin 222
chr13_+_23752267 0.72 ENSMUST00000091703.2
Hist1h3b
histone cluster 1, H3b
chr10_+_62252325 0.72 ENSMUST00000020278.5
Tacr2
tachykinin receptor 2
chr12_+_72441933 0.71 ENSMUST00000161284.1
Lrrc9
leucine rich repeat containing 9
chr7_-_110769345 0.71 ENSMUST00000098108.2
B430319F04Rik
RIKEN cDNA B430319F04 gene
chrX_-_56822308 0.71 ENSMUST00000135542.1
ENSMUST00000114766.1
Mtap7d3
MAP7 domain containing 3
chr1_+_89454769 0.69 ENSMUST00000027521.8
ENSMUST00000074945.5
Agap1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr10_-_62422427 0.68 ENSMUST00000020277.8
Hkdc1
hexokinase domain containing 1
chr6_-_124779686 0.67 ENSMUST00000147669.1
ENSMUST00000128697.1
ENSMUST00000032218.3
ENSMUST00000112475.2
Lrrc23
leucine rich repeat containing 23
chr13_+_111686303 0.67 ENSMUST00000047412.4
ENSMUST00000109271.2
Mier3
mesoderm induction early response 1, family member 3
chrX_+_169879596 0.64 ENSMUST00000112105.1
ENSMUST00000078947.5
Mid1
midline 1
chr4_+_109415631 0.64 ENSMUST00000106618.1
Ttc39a
tetratricopeptide repeat domain 39A
chr2_+_112379204 0.63 ENSMUST00000028552.3
Katnbl1
katanin p80 subunit B like 1
chr4_-_11386757 0.62 ENSMUST00000108313.1
ENSMUST00000108311.2
Esrp1
epithelial splicing regulatory protein 1
chr3_-_63851251 0.62 ENSMUST00000162269.2
ENSMUST00000159676.2
ENSMUST00000175947.1
Plch1
phospholipase C, eta 1
chr3_+_37348645 0.62 ENSMUST00000038885.3
Fgf2
fibroblast growth factor 2
chr12_+_3891728 0.61 ENSMUST00000172689.1
ENSMUST00000111186.1
Dnmt3a
DNA methyltransferase 3A
chr7_-_105574324 0.61 ENSMUST00000081165.7
Apbb1
amyloid beta (A4) precursor protein-binding, family B, member 1
chr19_+_25672408 0.61 ENSMUST00000053068.5
Dmrt2
doublesex and mab-3 related transcription factor 2
chr7_+_128246812 0.61 ENSMUST00000164710.1
ENSMUST00000070656.5
Tgfb1i1
transforming growth factor beta 1 induced transcript 1
chr1_+_135584773 0.60 ENSMUST00000067468.4
Gm4793
predicted gene 4793
chr17_-_32800938 0.60 ENSMUST00000080905.6
Zfp811
zinc finger protein 811

Network of associatons between targets according to the STRING database.

First level regulatory network of Nanog

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 7.5 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861) neuron projection maintenance(GO:1990535)
2.1 8.6 GO:0035524 proline transmembrane transport(GO:0035524)
1.9 5.6 GO:0072488 ammonium transmembrane transport(GO:0072488)
1.6 4.9 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.9 9.3 GO:0002441 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.9 13.5 GO:0015816 glycine transport(GO:0015816)
0.8 6.8 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.7 0.7 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685)
0.7 2.7 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.7 2.0 GO:0042668 auditory receptor cell fate determination(GO:0042668) negative regulation of forebrain neuron differentiation(GO:2000978)
0.6 1.9 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.6 10.7 GO:0030953 astral microtubule organization(GO:0030953)
0.6 1.9 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.6 2.4 GO:0015824 proline transport(GO:0015824) L-serine transport(GO:0015825)
0.6 1.2 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.6 3.6 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.5 2.2 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780)
0.5 5.2 GO:0030916 otic vesicle formation(GO:0030916)
0.5 3.6 GO:0035989 tendon development(GO:0035989)
0.5 2.0 GO:0061743 motor learning(GO:0061743)
0.4 1.3 GO:0071661 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165) granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663)
0.4 3.5 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.4 2.5 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678) positive regulation of guanylate cyclase activity(GO:0031284)
0.4 1.9 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.4 2.2 GO:0072318 clathrin coat disassembly(GO:0072318)
0.3 0.6 GO:0060128 corticotropin hormone secreting cell differentiation(GO:0060128)
0.3 0.9 GO:1901355 response to rapamycin(GO:1901355)
0.3 2.0 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.3 0.9 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.3 3.2 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.2 2.1 GO:0002432 granuloma formation(GO:0002432)
0.2 2.1 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2 1.1 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.2 0.6 GO:0061402 positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
0.2 0.6 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.2 28.2 GO:0007586 digestion(GO:0007586)
0.2 0.8 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.2 1.1 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.2 2.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.2 1.3 GO:0044838 cell quiescence(GO:0044838) regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.2 4.0 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.2 0.5 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344) chromosome movement towards spindle pole(GO:0051305) formin-nucleated actin cable assembly(GO:0070649)
0.2 1.8 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.2 5.2 GO:0008340 determination of adult lifespan(GO:0008340)
0.2 1.5 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.2 2.7 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.2 1.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.2 0.5 GO:0071918 urea transmembrane transport(GO:0071918)
0.2 0.6 GO:0061055 myotome development(GO:0061055)
0.1 1.1 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 1.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 1.3 GO:0071732 cellular response to nitric oxide(GO:0071732)
0.1 0.8 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1 0.5 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 2.2 GO:0045332 phospholipid translocation(GO:0045332)
0.1 0.8 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 2.1 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 1.0 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 2.4 GO:0097186 amelogenesis(GO:0097186)
0.1 1.4 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.3 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 1.5 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.1 0.9 GO:0045835 brain renin-angiotensin system(GO:0002035) negative regulation of meiotic nuclear division(GO:0045835)
0.1 0.9 GO:0018065 protein-cofactor linkage(GO:0018065)
0.1 0.6 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.1 0.4 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 1.0 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 0.6 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.3 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002587)
0.1 3.9 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 1.5 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.1 0.3 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.1 1.4 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.1 1.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.4 GO:0006363 transcription initiation from RNA polymerase I promoter(GO:0006361) termination of RNA polymerase I transcription(GO:0006363)
0.1 2.1 GO:0034508 centromere complex assembly(GO:0034508)
0.1 0.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 1.9 GO:0042755 eating behavior(GO:0042755)
0.1 2.4 GO:0006182 cGMP biosynthetic process(GO:0006182)
0.1 0.8 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.1 0.4 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055) ribosomal small subunit export from nucleus(GO:0000056)
0.1 1.0 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.5 GO:0072658 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 1.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 1.8 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.6 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.3 GO:0016584 nucleosome positioning(GO:0016584)
0.0 2.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.4 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 2.4 GO:0042398 cellular modified amino acid biosynthetic process(GO:0042398)
0.0 0.4 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.3 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.6 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.0 0.9 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.3 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.0 0.2 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.0 0.3 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.3 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.2 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.7 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 2.9 GO:0000910 cytokinesis(GO:0000910)
0.0 0.1 GO:2000195 negative regulation of female gonad development(GO:2000195)
0.0 0.8 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.3 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 1.1 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.1 GO:1904177 regulation of adipose tissue development(GO:1904177)
0.0 0.1 GO:0010616 negative regulation of cardiac muscle adaptation(GO:0010616)
0.0 1.2 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.4 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 1.0 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.1 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 1.2 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.0 0.2 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.8 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.2 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 1.9 GO:0071773 response to BMP(GO:0071772) cellular response to BMP stimulus(GO:0071773)
0.0 0.3 GO:0007625 grooming behavior(GO:0007625)
0.0 0.1 GO:0010452 histone H3-K36 methylation(GO:0010452) uterus morphogenesis(GO:0061038)
0.0 0.2 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.4 GO:0000154 rRNA modification(GO:0000154)
0.0 0.5 GO:0050919 negative chemotaxis(GO:0050919)
0.0 1.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 8.4 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.3 3.4 GO:0033093 Weibel-Palade body(GO:0033093)
0.3 2.9 GO:0000801 central element(GO:0000801)
0.3 2.0 GO:0000798 nuclear cohesin complex(GO:0000798)
0.3 3.6 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.3 0.8 GO:0000811 GINS complex(GO:0000811)
0.2 1.9 GO:0033269 internode region of axon(GO:0033269)
0.2 2.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.2 0.9 GO:0060187 cell pole(GO:0060187)
0.2 0.8 GO:0071148 TEAD-1-YAP complex(GO:0071148)
0.1 2.0 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 2.0 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 0.6 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.1 0.7 GO:0044305 calyx of Held(GO:0044305)
0.1 0.3 GO:0005687 U4 snRNP(GO:0005687)
0.1 1.0 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 1.4 GO:0042555 MCM complex(GO:0042555)
0.1 2.4 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 2.7 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 0.4 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.4 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 1.5 GO:0071565 nBAF complex(GO:0071565)
0.1 1.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 1.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.3 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 4.1 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 2.1 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.9 GO:0005685 U1 snRNP(GO:0005685)
0.0 3.0 GO:0031594 neuromuscular junction(GO:0031594)
0.0 3.2 GO:0005776 autophagosome(GO:0005776)
0.0 4.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 2.4 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 1.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.8 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 38.3 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 0.3 GO:0010369 chromocenter(GO:0010369)
0.0 4.1 GO:0032993 protein-DNA complex(GO:0032993)
0.0 2.5 GO:0005814 centriole(GO:0005814)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 3.9 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 6.4 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.9 GO:0031672 A band(GO:0031672)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 2.1 GO:0000776 kinetochore(GO:0000776)
0.0 5.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.6 GO:0005881 cytoplasmic microtubule(GO:0005881)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 13.5 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
1.1 11.8 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
1.0 11.0 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.8 5.8 GO:0004027 alcohol sulfotransferase activity(GO:0004027)
0.6 3.6 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.5 3.1 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.5 3.3 GO:0032027 myosin light chain binding(GO:0032027)
0.5 1.9 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.5 1.4 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.4 1.3 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.4 3.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.4 2.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.4 2.4 GO:0004111 creatine kinase activity(GO:0004111)
0.4 1.1 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.3 5.6 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.3 0.9 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.3 0.8 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.2 0.7 GO:0004995 tachykinin receptor activity(GO:0004995)
0.2 4.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 0.7 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.2 1.3 GO:0008172 S-methyltransferase activity(GO:0008172)
0.2 0.6 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.2 1.0 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2 1.4 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.2 2.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.2 0.9 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 4.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 1.3 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.2 6.7 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.2 1.4 GO:0048495 Roundabout binding(GO:0048495)
0.2 3.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.2 0.8 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.2 1.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.2 1.5 GO:0019966 interleukin-1 binding(GO:0019966)
0.2 31.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 1.9 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 2.5 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 2.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.3 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.1 0.6 GO:0031493 nucleosomal histone binding(GO:0031493)
0.1 3.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.4 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 1.2 GO:0019841 retinal binding(GO:0016918) retinol binding(GO:0019841)
0.1 1.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 0.9 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 0.7 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 2.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.5 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.5 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 1.0 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.9 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 3.2 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 1.0 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.3 GO:0030621 U4 snRNA binding(GO:0030621)
0.1 2.8 GO:0050699 WW domain binding(GO:0050699)
0.1 0.4 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1 1.2 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.1 0.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 3.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.4 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0052740 phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.8 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.6 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 1.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity(GO:0042328)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.0 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 1.1 GO:0070412 R-SMAD binding(GO:0070412)
0.0 3.5 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 5.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.6 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.2 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.2 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.6 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.6 GO:0042056 chemoattractant activity(GO:0042056)
0.0 1.1 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 8.4 GO:0005525 GTP binding(GO:0005525)
0.0 0.2 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.3 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.5 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.7 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.5 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 2.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 12.8 PID AURORA A PATHWAY Aurora A signaling
0.3 0.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1 8.3 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 6.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 3.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 2.9 PID AURORA B PATHWAY Aurora B signaling
0.1 5.3 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 5.5 PID CDC42 PATHWAY CDC42 signaling events
0.1 2.0 PID ATM PATHWAY ATM pathway
0.0 2.2 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.4 PID ATR PATHWAY ATR signaling pathway
0.0 1.0 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 2.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 7.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.3 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.1 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 2.6 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.5 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.9 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.1 PID P73PATHWAY p73 transcription factor network
0.0 3.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.7 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.6 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 11.6 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.5 15.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.3 16.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.3 4.7 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.3 6.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.3 3.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.2 6.1 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.2 1.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 3.1 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 2.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 2.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 0.8 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 9.2 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 1.9 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 5.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 7.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 0.7 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 1.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 0.8 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 0.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 2.1 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 2.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 0.9 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.8 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 2.6 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 0.6 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 1.3 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 1.1 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 2.2 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 2.1 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 1.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 3.5 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 2.3 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.8 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.3 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
0.0 1.0 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.3 REACTOME PHASE II CONJUGATION Genes involved in Phase II conjugation
0.0 0.4 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.9 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.2 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)