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GSE58827: Dynamics of the Mouse Liver

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Results for Maf_Nrl

Z-value: 1.10

Motif logo

Transcription factors associated with Maf_Nrl

Gene Symbol Gene ID Gene Info
ENSMUSG00000055435.6 avian musculoaponeurotic fibrosarcoma oncogene homolog
ENSMUSG00000040632.9 neural retina leucine zipper gene

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nrlmm10_v2_chr14_-_55524938_55524967-0.382.2e-02Click!
Mafmm10_v2_chr8_-_115706994_115707096-0.382.4e-02Click!

Activity profile of Maf_Nrl motif

Sorted Z-values of Maf_Nrl motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_39007019 13.61 ENSMUST00000025966.4
cytochrome P450, family 2, subfamily c, polypeptide 55
chr10_+_87860030 13.41 ENSMUST00000062862.6
insulin-like growth factor 1
chr10_+_87859593 12.31 ENSMUST00000126490.1
insulin-like growth factor 1
chr10_+_87859481 7.64 ENSMUST00000121952.1
insulin-like growth factor 1
chr10_+_87859255 6.87 ENSMUST00000105300.2
insulin-like growth factor 1
chr10_+_87859062 6.48 ENSMUST00000095360.4
insulin-like growth factor 1
chr9_-_46235260 6.29 ENSMUST00000121916.1
ENSMUST00000034586.2
apolipoprotein C-III
chr19_+_20601958 5.65 ENSMUST00000087638.3
aldehyde dehydrogenase family 1, subfamily A1
chr19_-_20727533 5.17 ENSMUST00000025656.3
aldehyde dehydrogenase family 1, subfamily A7
chr4_+_104766334 4.55 ENSMUST00000065072.6
complement component 8, beta polypeptide
chr4_+_104766308 4.49 ENSMUST00000031663.3
complement component 8, beta polypeptide
chr8_-_3878549 3.59 ENSMUST00000011445.6
CD209d antigen
chr4_+_141239499 3.41 ENSMUST00000141834.2
Rho guanine nucleotide exchange factor (GEF) 19
chrX_+_42502533 3.34 ENSMUST00000005839.4
SH2 domain protein 1A
chr19_-_21652779 3.19 ENSMUST00000179768.1
ENSMUST00000178523.1
ENSMUST00000038830.3
RIKEN cDNA 1110059E24 gene
chr9_-_46235631 3.13 ENSMUST00000118649.1
apolipoprotein C-III
chr1_-_136260873 3.09 ENSMUST00000086395.5
G protein-coupled receptor 25
chr4_-_82705735 2.61 ENSMUST00000155821.1
nuclear factor I/B
chr14_+_37068042 2.55 ENSMUST00000057176.3
leucine-rich repeat, immunoglobulin-like and transmembrane domains 2
chr7_+_51878967 2.54 ENSMUST00000051912.6
growth arrest specific 2
chr9_-_70141484 2.48 ENSMUST00000034749.8
family with sequence similarity 81, member A
chr15_+_10223974 2.48 ENSMUST00000128450.1
ENSMUST00000148257.1
ENSMUST00000128921.1
prolactin receptor
chr16_+_20733104 2.41 ENSMUST00000115423.1
ENSMUST00000007171.6
chordin
chr7_+_51879041 2.35 ENSMUST00000107591.2
growth arrest specific 2
chr5_-_113081579 2.31 ENSMUST00000131708.1
ENSMUST00000117143.1
ENSMUST00000119627.1
crystallin, beta B3
chr7_-_4789541 2.13 ENSMUST00000168578.1
transmembrane protein 238
chr14_-_37048957 2.10 ENSMUST00000022338.5
retinal G protein coupled receptor
chr17_+_12584183 2.03 ENSMUST00000046959.7
solute carrier family 22 (organic cation transporter), member 2
chr8_-_3926798 2.02 ENSMUST00000171635.1
ENSMUST00000111014.1
ENSMUST00000084086.2
CD209b antigen
chr1_+_74284930 1.96 ENSMUST00000113805.1
ENSMUST00000027370.6
ENSMUST00000087226.4
paroxysmal nonkinesiogenic dyskinesia
chr14_-_73385225 1.91 ENSMUST00000022704.7
integral membrane protein 2B
chr4_+_141242850 1.89 ENSMUST00000138096.1
ENSMUST00000006618.2
ENSMUST00000125392.1
Rho guanine nucleotide exchange factor (GEF) 19
chr16_-_46155077 1.87 ENSMUST00000059524.5
predicted gene 4737
chrX_+_42502596 1.84 ENSMUST00000115070.1
ENSMUST00000153948.1
SH2 domain protein 1A
chr10_+_4710119 1.83 ENSMUST00000105588.1
ENSMUST00000105589.1
estrogen receptor 1 (alpha)
chr17_+_46428930 1.82 ENSMUST00000024764.5
ENSMUST00000165993.1
cysteine-rich protein 3
chr4_-_141239453 1.79 ENSMUST00000168138.1
RIKEN cDNA C630004L07 gene
chr17_+_46428917 1.72 ENSMUST00000113465.3
cysteine-rich protein 3
chr1_+_127729405 1.71 ENSMUST00000038006.6
amino carboxymuconate semialdehyde decarboxylase
chr4_+_143349757 1.61 ENSMUST00000052458.2
leucine rich repeat containing 38
chr1_+_88095054 1.58 ENSMUST00000150634.1
ENSMUST00000058237.7
UDP glucuronosyltransferase 1 family, polypeptide A7C
chr13_-_64129305 1.58 ENSMUST00000099441.4
solute carrier family 35, member D2
chr16_+_64851991 1.58 ENSMUST00000067744.7
CGG triplet repeat binding protein 1
chr3_+_135826075 1.55 ENSMUST00000029810.5
solute carrier family 39 (metal ion transporter), member 8
chr6_-_29380426 1.53 ENSMUST00000147483.2
opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)
chr11_-_53423123 1.51 ENSMUST00000036045.5
liver-expressed antimicrobial peptide 2
chr11_-_77725281 1.51 ENSMUST00000078623.4
crystallin, beta A1
chr8_+_119437118 1.50 ENSMUST00000152420.1
ENSMUST00000098365.3
oxidative stress induced growth inhibitor 1
chr6_+_17491216 1.45 ENSMUST00000080469.5
met proto-oncogene
chr2_+_69897220 1.43 ENSMUST00000055758.9
ENSMUST00000112251.2
ubiquitin protein ligase E3 component n-recognin 3
chr13_+_48261427 1.41 ENSMUST00000021810.1
inhibitor of DNA binding 4
chr9_-_107679592 1.38 ENSMUST00000010205.7
guanine nucleotide binding protein, alpha transducing 1
chr5_-_34187670 1.38 ENSMUST00000042701.6
ENSMUST00000119171.1
Max dimerization protein 4
chr10_-_24101951 1.37 ENSMUST00000170267.1
trace amine-associated receptor 8C
chrX_-_143933204 1.37 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
doublecortin
chr6_+_113472276 1.32 ENSMUST00000147316.1
interleukin 17 receptor C
chr19_+_37685581 1.28 ENSMUST00000073391.4
cytochrome P450, family 26, subfamily c, polypeptide 1
chr3_+_94398517 1.27 ENSMUST00000050975.3
leucine rich repeat and Ig domain containing 4
chr2_-_148040196 1.27 ENSMUST00000136555.1
RIKEN cDNA 9030622O22 gene
chr9_+_46228580 1.26 ENSMUST00000034588.8
apolipoprotein A-I
chr11_-_50210765 1.25 ENSMUST00000143379.1
ENSMUST00000015981.5
ENSMUST00000102774.4
sequestosome 1
chr4_-_6275629 1.21 ENSMUST00000029905.1
cytochrome P450, family 7, subfamily a, polypeptide 1
chr5_-_77408034 1.20 ENSMUST00000163898.1
ENSMUST00000046746.6
insulin-like growth factor binding protein 7
chr19_-_24861828 1.19 ENSMUST00000047666.4
phosphoglucomutase 5
chr5_-_139813237 1.19 ENSMUST00000110832.1
transmembrane protein 184a
chr6_+_71199827 1.16 ENSMUST00000067492.7
fatty acid binding protein 1, liver
chr7_+_19228334 1.16 ENSMUST00000063976.8
optic atrophy 3
chr2_+_34772089 1.16 ENSMUST00000028222.6
ENSMUST00000100171.2
heat shock protein 5
chr11_-_75422524 1.16 ENSMUST00000125982.1
ENSMUST00000137103.1
serine (or cysteine) peptidase inhibitor, clade F, member 1
chr17_+_33920522 1.15 ENSMUST00000172489.1
TAP binding protein
chr15_+_57694651 1.15 ENSMUST00000096430.4
zinc fingers and homeoboxes 2
chr3_-_33083016 1.14 ENSMUST00000078226.3
ENSMUST00000108224.1
peroxisomal biogenesis factor 5-like
chr1_-_183369529 1.14 ENSMUST00000069922.5
melanoma inhibitory activity 3
chr6_+_117168535 1.12 ENSMUST00000112866.1
ENSMUST00000112871.1
ENSMUST00000073043.4
chemokine (C-X-C motif) ligand 12
chr7_+_101321703 1.10 ENSMUST00000174291.1
ENSMUST00000167888.2
ENSMUST00000172662.1
ENSMUST00000173270.1
ENSMUST00000174083.1
START domain containing 10
chr5_+_102845007 1.10 ENSMUST00000070000.4
Rho GTPase activating protein 24
chr6_+_90462562 1.10 ENSMUST00000032174.5
Kruppel-like factor 15
chr4_-_57300362 1.10 ENSMUST00000153926.1
protein tyrosine phosphatase, non-receptor type 3
chr2_+_101624696 1.10 ENSMUST00000044031.3
recombination activating gene 2
chr2_+_59160884 1.08 ENSMUST00000037903.8
plakophilin 4
chr6_-_29380513 1.05 ENSMUST00000080428.6
opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)
chr14_+_54254124 1.04 ENSMUST00000180359.1
abhydrolase domain containing 4
chr17_-_34031544 1.04 ENSMUST00000025186.8
solute carrier family 39 (zinc transporter), member 7
chr1_+_59256906 1.03 ENSMUST00000160662.1
ENSMUST00000114248.2
cyclin-dependent kinase 15
chr4_+_56740070 1.03 ENSMUST00000181745.1
predicted gene, 26657
chr2_+_126034967 1.03 ENSMUST00000110442.1
fibroblast growth factor 7
chr12_+_105336922 1.02 ENSMUST00000180503.1
RIKEN cDNA 2810011L19 gene
chr3_-_97297778 1.02 ENSMUST00000181368.1
predicted gene, 17608
chr7_+_121707189 1.01 ENSMUST00000065310.2
RIKEN cDNA 1700069B07 gene
chr2_-_156887056 1.00 ENSMUST00000029164.2
Src-like-adaptor 2
chr17_-_34031684 1.00 ENSMUST00000169397.1
solute carrier family 39 (zinc transporter), member 7
chr1_-_153851189 0.99 ENSMUST00000059607.6
RIKEN cDNA 5830403L16 gene
chr17_-_34031644 0.99 ENSMUST00000171872.1
solute carrier family 39 (zinc transporter), member 7
chr6_+_83054653 0.98 ENSMUST00000092618.6
ancient ubiquitous protein 1
chr3_-_84220853 0.96 ENSMUST00000154152.1
ENSMUST00000107693.2
ENSMUST00000107695.2
tripartite motif-containing 2
chr5_+_31116702 0.93 ENSMUST00000013771.8
tripartite motif-containing 54
chr17_-_26069409 0.92 ENSMUST00000120691.1
RAB11 family interacting protein 3 (class II)
chr11_+_69991633 0.92 ENSMUST00000108592.1
gamma-aminobutyric acid receptor associated protein
chr2_-_32694120 0.91 ENSMUST00000028148.4
folylpolyglutamyl synthetase
chr4_-_63154130 0.91 ENSMUST00000030041.4
alpha 1 microglobulin/bikunin
chr2_-_156887172 0.89 ENSMUST00000109561.3
Src-like-adaptor 2
chr8_-_129065488 0.87 ENSMUST00000125112.1
ENSMUST00000108747.2
ENSMUST00000095158.4
coiled-coil domain containing 7
chr5_-_24423516 0.85 ENSMUST00000030814.6
cyclin-dependent kinase 5
chr5_-_138155694 0.84 ENSMUST00000132318.1
ENSMUST00000049393.8
zinc finger protein 113
chr11_+_87663087 0.84 ENSMUST00000165679.1
ring finger protein 43
chr14_-_49525840 0.83 ENSMUST00000138884.1
ENSMUST00000074368.4
ENSMUST00000123534.1
solute carrier family 35, member F4
chr11_+_80428598 0.82 ENSMUST00000173938.1
ENSMUST00000017572.7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr19_+_4855129 0.82 ENSMUST00000119694.1
cathepsin F
chr18_-_35655185 0.81 ENSMUST00000097619.1
proline rich basic protein 1
chr13_+_42709482 0.81 ENSMUST00000066928.5
ENSMUST00000148891.1
phosphatase and actin regulator 1
chr5_+_31116722 0.80 ENSMUST00000114637.1
tripartite motif-containing 54
chr16_-_62847008 0.79 ENSMUST00000089289.5
ADP-ribosylation factor-like 13B
chr3_+_95282897 0.79 ENSMUST00000039537.7
ENSMUST00000107187.2
family with sequence similarity 63, member A
chr15_-_41869703 0.79 ENSMUST00000054742.5
actin-binding Rho activating protein
chr2_-_76982455 0.78 ENSMUST00000011934.5
ENSMUST00000099981.2
ENSMUST00000099980.3
ENSMUST00000111882.2
ENSMUST00000140091.1
titin
chr12_-_87919857 0.77 ENSMUST00000180053.1
predicted pseudogene 2035
chrX_+_150594420 0.77 ENSMUST00000112713.2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr2_-_38926217 0.77 ENSMUST00000076275.4
ENSMUST00000142130.1
nuclear receptor subfamily 6, group A, member 1
chr19_+_42255704 0.76 ENSMUST00000087123.5
golgi autoantigen, golgin subfamily a, 7B
chr13_+_84222286 0.75 ENSMUST00000057495.8
transmembrane protein 161B
chr3_-_84270782 0.75 ENSMUST00000054990.4
tripartite motif-containing 2
chr10_-_24109582 0.74 ENSMUST00000041180.5
trace amine-associated receptor 9
chr13_-_54611332 0.74 ENSMUST00000091609.4
clathrin, light polypeptide (Lcb)
chr15_-_76232554 0.74 ENSMUST00000166428.1
plectin
chr9_-_114844090 0.73 ENSMUST00000047013.3
CKLF-like MARVEL transmembrane domain containing 8
chr12_-_85824506 0.73 ENSMUST00000021676.5
ENSMUST00000142331.1
RIKEN cDNA 0610007P14 gene
chr3_-_146770603 0.73 ENSMUST00000106138.1
protein kinase, cAMP dependent, catalytic, beta
chr13_-_31559333 0.72 ENSMUST00000170573.1
RIKEN cDNA A530084C06 gene
chr4_+_138454305 0.71 ENSMUST00000050918.3
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr11_+_76202007 0.71 ENSMUST00000094014.3
family with sequence similarity 57, member A
chr15_-_100687908 0.71 ENSMUST00000023775.7
chymotrypsin-like elastase family, member 1
chr9_+_103112072 0.71 ENSMUST00000035155.6
RAB6B, member RAS oncogene family
chr16_+_17331371 0.70 ENSMUST00000023450.6
ENSMUST00000161034.1
serine (or cysteine) peptidase inhibitor, clade D, member 1
chr18_+_5593566 0.70 ENSMUST00000160910.1
zinc finger E-box binding homeobox 1
chr9_-_63399216 0.70 ENSMUST00000168665.1
RIKEN cDNA 2300009A05 gene
chr14_+_120478443 0.68 ENSMUST00000062117.6
RAS related protein 2a
chr2_+_126034647 0.67 ENSMUST00000064794.7
fibroblast growth factor 7
chr2_-_26092149 0.67 ENSMUST00000114159.2
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr12_+_80644212 0.67 ENSMUST00000085245.5
solute carrier family 39 (zinc transporter), member 9
chr14_-_26534870 0.67 ENSMUST00000139075.1
ENSMUST00000102956.1
sarcolemma associated protein
chr19_+_39060998 0.66 ENSMUST00000087236.4
cytochrome P450, family 2, subfamily c, polypeptide 65
chr12_+_76081645 0.66 ENSMUST00000154509.1
spectrin repeat containing, nuclear envelope 2
chr10_+_86705811 0.66 ENSMUST00000061458.7
ENSMUST00000075632.6
cDNA sequence BC030307
chr11_+_76202084 0.66 ENSMUST00000169560.1
family with sequence similarity 57, member A
chr3_-_79145875 0.65 ENSMUST00000118340.1
Rap guanine nucleotide exchange factor (GEF) 2
chr2_-_130397525 0.65 ENSMUST00000028897.7
carboxypeptidase X 1 (M14 family)
chr4_-_118690463 0.65 ENSMUST00000060562.3
olfactory receptor 1342
chr1_-_74749221 0.65 ENSMUST00000081636.6
protein kinase, AMP-activated, gamma 3 non-catatlytic subunit
chr16_+_20672716 0.64 ENSMUST00000044783.7
ENSMUST00000115463.1
ENSMUST00000142344.1
ENSMUST00000073840.5
ENSMUST00000140576.1
ENSMUST00000115457.1
eukaryotic translation initiation factor 4, gamma 1
chr11_-_120630516 0.64 ENSMUST00000106181.1
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chrX_-_18461371 0.63 ENSMUST00000044188.4
RIKEN cDNA 4930578C19 gene
chr17_-_35172608 0.63 ENSMUST00000173106.1
allograft inflammatory factor 1
chr9_+_104002546 0.62 ENSMUST00000035167.8
ENSMUST00000117054.1
nephronophthisis 3 (adolescent)
chr10_+_24076500 0.62 ENSMUST00000051133.5
trace amine-associated receptor 8A
chr5_-_30196418 0.62 ENSMUST00000125367.1
G protein-coupled receptor 113
chr16_-_88563166 0.62 ENSMUST00000049697.4
claudin 8
chr6_+_110645572 0.61 ENSMUST00000071076.6
ENSMUST00000172951.1
glutamate receptor, metabotropic 7
chr16_+_20548577 0.61 ENSMUST00000003319.5
ATP-binding cassette, sub-family F (GCN20), member 3
chr16_-_36990449 0.60 ENSMUST00000075869.6
F-box protein 40
chr10_-_14718191 0.60 ENSMUST00000020016.4
gap junction protein, epsilon 1
chr2_-_146511899 0.59 ENSMUST00000131824.1
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr12_+_30584429 0.58 ENSMUST00000057151.8
transmembrane protein 18
chr15_+_25622525 0.58 ENSMUST00000110457.1
ENSMUST00000137601.1
myosin X
chr8_-_11478618 0.58 ENSMUST00000033900.5
RAB20, member RAS oncogene family
chr6_+_21985903 0.58 ENSMUST00000137437.1
ENSMUST00000115383.2
cadherin-like and PC-esterase domain containing 1
chr5_-_125294107 0.58 ENSMUST00000127148.1
scavenger receptor class B, member 1
chr1_+_127306706 0.58 ENSMUST00000171405.1
mannoside acetylglucosaminyltransferase 5
chr1_+_87124946 0.57 ENSMUST00000044878.3
alkaline phosphatase 3, intestine, not Mn requiring
chr9_+_45055211 0.57 ENSMUST00000114663.2
myelin protein zero-like 3
chr14_-_54253907 0.56 ENSMUST00000128231.1
defender against cell death 1
chr9_+_45055166 0.56 ENSMUST00000114664.1
ENSMUST00000093856.3
myelin protein zero-like 3
chrX_+_93183227 0.55 ENSMUST00000088133.3
cDNA sequence BC061195
chr12_+_35047180 0.55 ENSMUST00000048519.9
ENSMUST00000163677.1
sorting nexin 13
chr11_-_97115327 0.55 ENSMUST00000001484.2
T-box 21
chr15_-_85503227 0.55 ENSMUST00000178942.1
RIKEN cDNA 7530416G11 gene
chrX_+_7638674 0.54 ENSMUST00000128890.1
synaptophysin
chr6_+_41538218 0.54 ENSMUST00000103291.1
T cell receptor beta, constant region 1
chr2_-_30093642 0.54 ENSMUST00000102865.4
zinc finger, DHHC domain containing 12
chr15_-_67113909 0.54 ENSMUST00000092640.5
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr4_+_155839724 0.53 ENSMUST00000030947.3
matrix-remodelling associated 8
chr12_-_113361232 0.53 ENSMUST00000103423.1
Immunoglobulin heavy constant gamma 3
chr10_-_42583628 0.53 ENSMUST00000019938.4
nuclear receptor subfamily 2, group E, member 1
chr6_+_21986438 0.52 ENSMUST00000115382.1
cadherin-like and PC-esterase domain containing 1
chr13_-_67332525 0.52 ENSMUST00000168892.1
ENSMUST00000109735.2
zinc finger protein 595
chr2_-_167188787 0.52 ENSMUST00000059826.8
potassium voltage gated channel, Shab-related subfamily, member 1
chr4_+_59003121 0.52 ENSMUST00000095070.3
ENSMUST00000174664.1
DnaJ (Hsp40) homolog, subfamily C, member 25
predicted gene 20503
chr9_-_57606234 0.52 ENSMUST00000045068.8
complexin 3
chr11_+_82035569 0.52 ENSMUST00000000193.5
chemokine (C-C motif) ligand 2
chr10_+_69213084 0.51 ENSMUST00000163497.1
ENSMUST00000164212.1
ENSMUST00000067908.7
Rho-related BTB domain containing 1
chr1_-_163725123 0.50 ENSMUST00000159679.1
methyltransferase like 11B
chr9_-_44965519 0.50 ENSMUST00000125642.1
ENSMUST00000117506.1
ENSMUST00000117549.1
ubiquitination factor E4A, UFD2 homolog (S. cerevisiae)
chr14_-_34588607 0.50 ENSMUST00000090040.4
LIM domain binding 3
chr4_-_57300751 0.50 ENSMUST00000151964.1
protein tyrosine phosphatase, non-receptor type 3
chr6_-_39118211 0.50 ENSMUST00000038398.6
poly (ADP-ribose) polymerase family, member 12
chr15_+_83779999 0.49 ENSMUST00000046168.5
metallophosphoesterase domain containing 1
chr7_-_45136102 0.49 ENSMUST00000125500.1
FMS-like tyrosine kinase 3 ligand
chr8_+_46739745 0.49 ENSMUST00000034041.7
interferon regulatory factor 2
chr8_+_44950208 0.48 ENSMUST00000098796.3
FAT tumor suppressor homolog 1 (Drosophila)
chr9_-_87731248 0.48 ENSMUST00000034991.7
T-box18
chr16_+_13358375 0.48 ENSMUST00000149359.1
MKL/myocardin-like 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Maf_Nrl

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.8 46.7 GO:1904073 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
2.4 9.4 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
1.2 13.6 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.8 5.6 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.8 1.6 GO:0046271 phenylpropanoid metabolic process(GO:0009698) coumarin metabolic process(GO:0009804) phenylpropanoid catabolic process(GO:0046271)
0.7 1.4 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.7 2.6 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.6 1.7 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.6 9.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.5 6.0 GO:0018298 protein-chromophore linkage(GO:0018298)
0.5 0.5 GO:0002436 immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265)
0.5 2.4 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.5 1.9 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.5 6.5 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.4 2.5 GO:0038161 prolactin signaling pathway(GO:0038161)
0.4 1.2 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.3 1.3 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.3 1.8 GO:0060523 Sertoli cell proliferation(GO:0060011) prostate epithelial cord elongation(GO:0060523)
0.3 5.2 GO:0006968 cellular defense response(GO:0006968)
0.3 0.9 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.3 1.2 GO:0043056 forward locomotion(GO:0043056)
0.3 2.0 GO:0001878 response to yeast(GO:0001878)
0.3 0.9 GO:0048209 regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
0.3 1.7 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.3 1.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.3 1.4 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342)
0.3 1.9 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.3 1.5 GO:2000210 positive regulation of anoikis(GO:2000210)
0.2 1.2 GO:1904253 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.2 0.5 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.2 0.7 GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
0.2 2.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.2 0.7 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.2 1.7 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.2 1.5 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.2 4.6 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.2 1.2 GO:0018992 germ-line sex determination(GO:0018992)
0.2 2.0 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.2 0.6 GO:0015920 regulation of phosphatidylcholine catabolic process(GO:0010899) lipopolysaccharide transport(GO:0015920)
0.2 0.9 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.2 0.5 GO:2000474 regulation of opioid receptor signaling pathway(GO:2000474)
0.2 1.6 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.2 1.1 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.2 0.6 GO:0014900 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.1 0.3 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.1 0.4 GO:0060364 embryonic nail plate morphogenesis(GO:0035880) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364)
0.1 0.4 GO:0051659 positive regulation of endoplasmic reticulum calcium ion concentration(GO:0032470) maintenance of mitochondrion location(GO:0051659) relaxation of skeletal muscle(GO:0090076)
0.1 0.8 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.5 GO:0060857 establishment of glial blood-brain barrier(GO:0060857)
0.1 0.7 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.7 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 2.7 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.1 0.6 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.1 1.4 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 2.0 GO:0051608 histamine transport(GO:0051608)
0.1 0.6 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 1.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.6 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.4 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.1 1.9 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.1 0.2 GO:0060492 foregut regionalization(GO:0060423) lung field specification(GO:0060424) lung induction(GO:0060492)
0.1 0.3 GO:2000978 trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of forebrain neuron differentiation(GO:2000978)
0.1 0.7 GO:0051541 elastin metabolic process(GO:0051541) pancreas morphogenesis(GO:0061113)
0.1 0.8 GO:0021943 formation of radial glial scaffolds(GO:0021943)
0.1 0.6 GO:0060178 regulation of exocyst localization(GO:0060178)
0.1 0.6 GO:0090383 phagosome acidification(GO:0090383)
0.1 0.3 GO:0061552 vestibulocochlear nerve structural organization(GO:0021649) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835)
0.1 0.7 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.4 GO:0042908 xenobiotic transport(GO:0042908)
0.1 0.5 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.1 0.8 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.4 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.1 1.1 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 1.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 0.9 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.4 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.1 1.7 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.1 0.7 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 0.3 GO:0070537 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) histone H2A K63-linked deubiquitination(GO:0070537)
0.1 0.7 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.1 0.8 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.3 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.3 GO:0090168 Golgi reassembly(GO:0090168)
0.1 1.1 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 0.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.7 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 0.5 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.1 1.1 GO:0061318 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1 0.2 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.1 0.8 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.6 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.5 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.6 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.3 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.2 GO:0060128 otic vesicle formation(GO:0030916) corticotropin hormone secreting cell differentiation(GO:0060128)
0.0 0.5 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.2 GO:0060596 mammary placode formation(GO:0060596)
0.0 1.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 1.7 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.7 GO:0018345 protein palmitoylation(GO:0018345)
0.0 6.4 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.7 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.2 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.3 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.2 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0 0.4 GO:0048664 neuron fate determination(GO:0048664)
0.0 1.3 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 1.2 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.1 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.0 1.0 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.5 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.3 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.1 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.0 0.4 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.0 0.1 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.0 0.1 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.1 GO:0021995 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.0 0.2 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 0.2 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 4.3 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:0009624 response to nematode(GO:0009624)
0.0 0.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.6 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.4 GO:0051043 regulation of membrane protein ectodomain proteolysis(GO:0051043)
0.0 0.7 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.4 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.6 GO:0031424 keratinization(GO:0031424)
0.0 0.0 GO:0070368 positive regulation of hepatocyte differentiation(GO:0070368)
0.0 0.3 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.5 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 0.7 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.4 GO:0036010 protein localization to endosome(GO:0036010)
0.0 1.7 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.2 GO:1990000 amyloid fibril formation(GO:1990000)
0.0 0.1 GO:0046490 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
0.0 0.3 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 0.2 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 1.3 GO:0030641 regulation of cellular pH(GO:0030641)
0.0 0.8 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 0.1 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.9 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.6 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 46.7 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) insulin-like growth factor ternary complex(GO:0042567)
1.0 10.7 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.8 9.0 GO:0005579 membrane attack complex(GO:0005579)
0.4 1.2 GO:0044753 amphisome(GO:0044753)
0.3 0.9 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.3 1.8 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.3 0.8 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.2 1.2 GO:0005914 spot adherens junction(GO:0005914)
0.2 1.7 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.2 0.6 GO:0097543 ciliary inversin compartment(GO:0097543)
0.2 1.0 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 1.1 GO:0042825 TAP complex(GO:0042825)
0.1 0.5 GO:0044299 C-fiber(GO:0044299)
0.1 2.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 1.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 1.2 GO:0043203 axon hillock(GO:0043203)
0.1 1.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.6 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 1.2 GO:0045179 apical cortex(GO:0045179)
0.1 0.8 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.4 GO:0031673 H zone(GO:0031673)
0.1 2.0 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 1.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.7 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 1.4 GO:0000421 autophagosome membrane(GO:0000421)
0.1 1.9 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.1 0.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.7 GO:0034992 lamellipodium membrane(GO:0031258) microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.8 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 1.4 GO:0030057 desmosome(GO:0030057)
0.1 0.5 GO:0070578 RISC-loading complex(GO:0070578)
0.1 0.9 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.2 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.1 0.3 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 0.6 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.5 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.7 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.6 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.8 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 2.9 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.6 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0034709 methylosome(GO:0034709)
0.0 0.5 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.8 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.6 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.5 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.1 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.4 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.0 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.7 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.5 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.1 GO:0030175 filopodium(GO:0030175)
0.0 2.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 2.0 GO:0005770 late endosome(GO:0005770)
0.0 0.1 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.8 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
3.4 13.6 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
2.7 10.7 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
1.2 46.7 GO:0043539 insulin-like growth factor receptor binding(GO:0005159) protein serine/threonine kinase activator activity(GO:0043539)
0.7 2.0 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
0.6 5.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.6 1.8 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.5 2.5 GO:0004925 prolactin receptor activity(GO:0004925)
0.4 1.3 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.4 1.1 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.4 1.5 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.3 2.4 GO:0045545 syndecan binding(GO:0045545)
0.3 1.7 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.3 0.9 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.3 1.9 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.2 2.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.2 5.6 GO:0005537 mannose binding(GO:0005537)
0.2 2.0 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.2 0.6 GO:0070905 serine binding(GO:0070905)
0.2 1.6 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.2 1.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.2 1.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.2 1.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.2 1.1 GO:0046979 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.2 7.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.6 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 0.6 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.4 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.1 0.7 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.5 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.7 GO:0008390 testosterone 16-alpha-hydroxylase activity(GO:0008390)
0.1 4.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.4 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.5 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 1.2 GO:0031433 telethonin binding(GO:0031433)
0.1 0.3 GO:0071820 N-box binding(GO:0071820)
0.1 0.4 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 0.4 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.1 0.8 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.7 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 1.0 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 1.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.9 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 0.6 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 3.1 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 0.4 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.1 0.7 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 0.9 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 0.7 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.7 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 1.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.2 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.1 0.9 GO:0050811 GABA receptor binding(GO:0050811)
0.0 1.2 GO:0051787 misfolded protein binding(GO:0051787)
0.0 1.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 1.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 1.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 5.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.3 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.6 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 1.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 1.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.2 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0 0.7 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 1.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.5 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.2 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.1 GO:0004452 isopentenyl-diphosphate delta-isomerase activity(GO:0004452)
0.0 0.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.2 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 1.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 2.5 GO:0017022 myosin binding(GO:0017022)
0.0 0.6 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.7 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 6.5 GO:0008017 microtubule binding(GO:0008017)
0.0 0.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 1.0 GO:0030332 cyclin binding(GO:0030332)
0.0 0.4 GO:0016805 dipeptidase activity(GO:0016805)
0.0 1.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0001972 retinoic acid binding(GO:0001972)
0.0 2.0 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 0.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.7 GO:0033558 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.0 0.2 GO:0048185 activin binding(GO:0048185)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 1.4 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 1.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.7 GO:0019003 GDP binding(GO:0019003)
0.0 0.2 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.7 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.7 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.1 GO:0016918 retinal binding(GO:0016918)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 46.9 PID IGF1 PATHWAY IGF1 pathway
0.1 4.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 2.9 PID BMP PATHWAY BMP receptor signaling
0.1 3.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 2.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.6 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.9 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.5 PID IL27 PATHWAY IL27-mediated signaling events
0.0 2.3 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.9 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.7 PID IL3 PATHWAY IL3-mediated signaling events
0.0 5.4 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 1.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.7 PID ARF 3PATHWAY Arf1 pathway
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.9 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.9 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.5 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 3.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.7 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.3 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.5 PID IL4 2PATHWAY IL4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 5.6 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.6 5.1 REACTOME OPSINS Genes involved in Opsins
0.5 11.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.3 9.0 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.2 4.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.2 2.0 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 4.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 2.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 2.6 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 1.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 1.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 3.0 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 1.3 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 1.9 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.1 1.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.6 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.6 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.9 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.9 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.4 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 1.6 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.5 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 2.1 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 1.9 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 1.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.6 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 0.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.5 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.8 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0 0.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA