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GSE58827: Dynamics of the Mouse Liver

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Results for Lef1

Z-value: 0.87

Motif logo

Transcription factors associated with Lef1

Gene Symbol Gene ID Gene Info
ENSMUSG00000027985.8 lymphoid enhancer binding factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Lef1mm10_v2_chr3_+_131112785_1311128030.019.3e-01Click!

Activity profile of Lef1 motif

Sorted Z-values of Lef1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_70474923 2.56 ENSMUST00000100043.2
trans-acting transcription factor 5
chr11_+_108920800 2.38 ENSMUST00000140821.1
axin2
chr13_-_62858364 1.60 ENSMUST00000021907.7
fructose bisphosphatase 2
chr6_-_52240841 1.57 ENSMUST00000121043.1
homeobox A10
chr10_-_128960965 1.55 ENSMUST00000026398.3
methyltransferase like 7B
chr11_-_26210553 1.53 ENSMUST00000101447.3
RIKEN cDNA 5730522E02 gene
chr11_+_96271453 1.53 ENSMUST00000000010.8
ENSMUST00000174042.1
homeobox B9
chr7_-_70366735 1.42 ENSMUST00000089565.5
nuclear receptor subfamily 2, group F, member 2
chr8_+_45507768 1.39 ENSMUST00000067065.7
ENSMUST00000098788.3
ENSMUST00000067107.7
ENSMUST00000171337.2
ENSMUST00000138049.1
ENSMUST00000141039.1
sorbin and SH3 domain containing 2
chr14_-_70524068 1.28 ENSMUST00000022692.3
surfactant associated protein C
chr19_-_30549516 1.22 ENSMUST00000025803.8
dickkopf homolog 1 (Xenopus laevis)
chr11_+_108921648 1.21 ENSMUST00000144511.1
axin2
chr2_-_116067391 1.15 ENSMUST00000140185.1
RIKEN cDNA 2700033N17 gene
chr11_+_108920342 1.11 ENSMUST00000052915.7
axin2
chr11_-_53773187 1.07 ENSMUST00000170390.1
predicted gene, 17334
chr2_+_96318014 1.05 ENSMUST00000135431.1
ENSMUST00000162807.2
leucine rich repeat containing 4C
chr12_+_76072016 1.00 ENSMUST00000131480.1
spectrin repeat containing, nuclear envelope 2
chr6_-_52246214 0.97 ENSMUST00000048026.8
homeobox A11
chr6_+_17463927 0.93 ENSMUST00000115442.1
met proto-oncogene
chr2_+_74704861 0.93 ENSMUST00000019749.3
homeobox D8
chrX_+_109095359 0.92 ENSMUST00000033598.8
SH3-binding domain glutamic acid-rich protein like
chr3_-_57575907 0.92 ENSMUST00000120977.1
WW domain containing transcription regulator 1
chr16_+_20097554 0.91 ENSMUST00000023509.3
kelch-like 24
chr2_+_74674929 0.91 ENSMUST00000001878.4
homeobox D12
chr18_+_37421418 0.90 ENSMUST00000053073.4
protocadherin beta 11
chr1_-_139781236 0.83 ENSMUST00000027612.8
ENSMUST00000111989.2
ENSMUST00000111986.2
predicted gene 4788
chr6_+_106118924 0.81 ENSMUST00000079416.5
contactin 4
chr6_+_17463826 0.81 ENSMUST00000140070.1
met proto-oncogene
chr14_+_101840501 0.80 ENSMUST00000159026.1
LIM domain only 7
chr2_-_116065047 0.78 ENSMUST00000028639.6
ENSMUST00000102538.4
Meis homeobox 2
chr15_-_54278420 0.77 ENSMUST00000079772.3
tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
chr3_-_116968827 0.77 ENSMUST00000119557.1
palmdelphin
chr3_-_57575760 0.76 ENSMUST00000029380.7
WW domain containing transcription regulator 1
chr13_-_84064772 0.76 ENSMUST00000182477.1
predicted gene, 17750
chr18_-_15403680 0.75 ENSMUST00000079081.6
aquaporin 4
chr3_-_122619442 0.75 ENSMUST00000162947.1
formin binding protein 1-like
chr18_-_62756275 0.74 ENSMUST00000067450.1
ENSMUST00000048109.5
RIKEN cDNA 2700046A07 gene
chr1_+_187997835 0.71 ENSMUST00000110938.1
estrogen-related receptor gamma
chrX_+_129749740 0.70 ENSMUST00000167619.2
ENSMUST00000037854.8
diaphanous homolog 2 (Drosophila)
chr5_-_51553896 0.69 ENSMUST00000132734.1
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr16_+_95257558 0.69 ENSMUST00000113862.1
ENSMUST00000113861.1
ENSMUST00000037154.7
ENSMUST00000113854.1
ENSMUST00000113855.1
potassium inwardly-rectifying channel, subfamily J, member 15
chr14_-_26442824 0.69 ENSMUST00000136635.1
ENSMUST00000125437.1
sarcolemma associated protein
chr3_-_30509681 0.69 ENSMUST00000173495.1
MDS1 and EVI1 complex locus
chr4_+_108479081 0.68 ENSMUST00000155068.1
zinc finger, CCHC domain containing 11
chr16_+_95257646 0.66 ENSMUST00000113856.1
ENSMUST00000134166.1
ENSMUST00000125847.1
ENSMUST00000140222.1
potassium inwardly-rectifying channel, subfamily J, member 15
chr14_+_101840602 0.66 ENSMUST00000159314.1
LIM domain only 7
chr11_+_88068242 0.66 ENSMUST00000018521.4
vascular endothelial zinc finger 1
chr3_-_116968969 0.64 ENSMUST00000143611.1
ENSMUST00000040097.7
palmdelphin
chr6_-_99096196 0.63 ENSMUST00000175886.1
forkhead box P1
chr12_-_56613270 0.63 ENSMUST00000072631.5
NK2 homeobox 9
chrX_-_38564519 0.63 ENSMUST00000016681.8
cullin 4B
chr14_-_101729690 0.62 ENSMUST00000066461.3
predicted gene 9922
chr17_-_79020816 0.61 ENSMUST00000168887.1
ENSMUST00000119284.1
protein kinase D3
chr17_+_74528467 0.61 ENSMUST00000182944.1
ENSMUST00000182597.1
ENSMUST00000182133.1
ENSMUST00000183224.1
baculoviral IAP repeat-containing 6
chr5_+_92137896 0.61 ENSMUST00000031355.6
USO1 vesicle docking factor
chr11_-_120661175 0.61 ENSMUST00000150458.1
notum pectinacetylesterase homolog (Drosophila)
chr2_+_15055274 0.60 ENSMUST00000069870.3
ADP-ribosylation factor-like 5B
chr7_+_82867327 0.59 ENSMUST00000082237.5
mex3 homolog B (C. elegans)
chr19_-_4334001 0.59 ENSMUST00000176653.1
lysine (K)-specific demethylase 2A
chr4_-_94650134 0.57 ENSMUST00000053419.2
leucine rich repeat containing 19
chr6_-_148944750 0.57 ENSMUST00000111562.1
ENSMUST00000081956.5
family with sequence similarity 60, member A
chr3_-_75956888 0.57 ENSMUST00000038563.7
ENSMUST00000167078.1
ENSMUST00000117242.1
golgi integral membrane protein 4
chr5_+_17574726 0.56 ENSMUST00000169603.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr2_+_74704615 0.55 ENSMUST00000151380.1
homeobox D8
chr17_+_37193889 0.55 ENSMUST00000038844.6
ubiquitin D
chr4_-_82705735 0.55 ENSMUST00000155821.1
nuclear factor I/B
chr2_-_60673654 0.54 ENSMUST00000059888.8
ENSMUST00000154764.1
integrin beta 6
chr6_-_52234902 0.54 ENSMUST00000125581.1
homeobox A10
chr5_-_62765618 0.54 ENSMUST00000159470.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr14_+_51114455 0.54 ENSMUST00000100645.3
epididymal protein 3B
chr14_+_101729907 0.53 ENSMUST00000100337.3
LIM domain only 7
chr2_-_65238573 0.53 ENSMUST00000090896.3
ENSMUST00000155082.1
Cobl-like 1
chr9_+_54863742 0.53 ENSMUST00000034843.7
iron responsive element binding protein 2
chr3_-_116423930 0.52 ENSMUST00000106491.2
CDC14 cell division cycle 14A
chr9_-_122903102 0.52 ENSMUST00000180877.1
ENSMUST00000180486.1
RIKEN cDNA A530083I20 gene
chr3_-_30509752 0.51 ENSMUST00000172697.1
MDS1 and EVI1 complex locus
chr16_+_95258036 0.51 ENSMUST00000113859.1
potassium inwardly-rectifying channel, subfamily J, member 15
chrX_+_129749830 0.51 ENSMUST00000113320.2
diaphanous homolog 2 (Drosophila)
chr2_+_103424120 0.49 ENSMUST00000171693.1
E74-like factor 5
chr3_-_30509462 0.49 ENSMUST00000173899.1
MDS1 and EVI1 complex locus
chr18_-_12862858 0.49 ENSMUST00000121774.1
oxysterol binding protein-like 1A
chr7_+_49246131 0.48 ENSMUST00000064395.6
neuron navigator 2
chrX_+_114474569 0.48 ENSMUST00000133447.1
kelch-like 4
chr13_+_9276477 0.48 ENSMUST00000174552.1
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chrX_+_114474312 0.47 ENSMUST00000113371.1
ENSMUST00000040504.5
kelch-like 4
chr2_+_103424056 0.47 ENSMUST00000028609.7
E74-like factor 5
chr6_+_17463749 0.47 ENSMUST00000115443.1
met proto-oncogene
chr8_-_54529951 0.47 ENSMUST00000067476.8
signal peptidase complex subunit 3 homolog (S. cerevisiae)
chr19_+_8591254 0.46 ENSMUST00000010251.3
ENSMUST00000170817.1
solute carrier family 22 (organic anion transporter), member 8
chr9_-_96752822 0.46 ENSMUST00000152594.1
zinc finger and BTB domain containing 38
chr3_-_116424007 0.46 ENSMUST00000090464.4
CDC14 cell division cycle 14A
chr19_-_34877880 0.46 ENSMUST00000112460.1
pantothenate kinase 1
chr2_-_148040196 0.46 ENSMUST00000136555.1
RIKEN cDNA 9030622O22 gene
chr14_-_93888732 0.46 ENSMUST00000068992.2
protocadherin 9
chr1_-_189343342 0.46 ENSMUST00000079451.6
potassium channel, subfamily K, member 2
chr3_+_20057802 0.46 ENSMUST00000002502.5
helicase-like transcription factor
chr2_-_64975762 0.46 ENSMUST00000156765.1
growth factor receptor bound protein 14
chr17_+_74528279 0.45 ENSMUST00000180037.1
ENSMUST00000024879.6
baculoviral IAP repeat-containing 6
chrX_+_114474509 0.45 ENSMUST00000113370.2
kelch-like 4
chr5_+_65131184 0.45 ENSMUST00000031089.5
ENSMUST00000101191.3
kelch-like 5
chr9_+_74976096 0.43 ENSMUST00000081746.5
family with sequence similarity 214, member A
chr9_+_120149733 0.43 ENSMUST00000068698.7
ENSMUST00000093773.1
ENSMUST00000111627.1
myelin-associated oligodendrocytic basic protein
chr7_-_73537621 0.43 ENSMUST00000172704.1
chromodomain helicase DNA binding protein 2
chr1_-_189343704 0.43 ENSMUST00000180044.1
ENSMUST00000110920.1
potassium channel, subfamily K, member 2
chr1_+_187997821 0.43 ENSMUST00000027906.6
estrogen-related receptor gamma
chr12_-_119238794 0.43 ENSMUST00000026360.8
integrin beta 8
chr9_+_44084944 0.43 ENSMUST00000176416.1
ENSMUST00000065461.7
ubiquitin specific peptidase 2
chr6_+_97991776 0.43 ENSMUST00000043628.6
microphthalmia-associated transcription factor
chr1_-_140183404 0.43 ENSMUST00000066859.6
ENSMUST00000111976.2
complement component factor h
chr9_+_72925622 0.42 ENSMUST00000038489.5
pygopus 1
chr6_-_124542281 0.42 ENSMUST00000159463.1
ENSMUST00000162844.1
ENSMUST00000160505.1
ENSMUST00000162443.1
complement component 1, s subcomponent
chr4_+_116558056 0.42 ENSMUST00000106475.1
GC-rich promoter binding protein 1-like 1
chr5_-_21785115 0.42 ENSMUST00000115193.1
ENSMUST00000115192.1
ENSMUST00000115195.1
ENSMUST00000030771.5
DnaJ (Hsp40) homolog, subfamily C, member 2
chr4_+_116557658 0.42 ENSMUST00000030460.8
GC-rich promoter binding protein 1-like 1
chr6_+_21985903 0.41 ENSMUST00000137437.1
ENSMUST00000115383.2
cadherin-like and PC-esterase domain containing 1
chr1_-_140183283 0.41 ENSMUST00000111977.1
complement component factor h
chr11_+_96292453 0.41 ENSMUST00000173432.1
homeobox B6
chr8_+_22624019 0.41 ENSMUST00000033936.6
dickkopf homolog 4 (Xenopus laevis)
chr5_+_47984793 0.41 ENSMUST00000170109.2
ENSMUST00000174421.1
ENSMUST00000173702.1
ENSMUST00000173107.1
slit homolog 2 (Drosophila)
chr10_+_69925954 0.41 ENSMUST00000181974.1
ENSMUST00000182795.1
ENSMUST00000182437.1
ankyrin 3, epithelial
chr13_-_104109576 0.41 ENSMUST00000109315.3
neurolysin (metallopeptidase M3 family)
chr3_+_5218516 0.40 ENSMUST00000175866.1
zinc finger homeodomain 4
chr10_-_25536114 0.40 ENSMUST00000179685.1
small leucine-rich protein 1
chr10_+_69925484 0.39 ENSMUST00000182692.1
ENSMUST00000092433.5
ankyrin 3, epithelial
chr6_+_21986438 0.39 ENSMUST00000115382.1
cadherin-like and PC-esterase domain containing 1
chr17_-_88065028 0.39 ENSMUST00000130379.1
F-box protein 11
chr1_+_135232045 0.39 ENSMUST00000110798.3
predicted gene 4204
chr1_-_136131171 0.38 ENSMUST00000146091.3
ENSMUST00000165464.1
ENSMUST00000166747.1
ENSMUST00000134998.1
predicted gene 15850
chr10_+_69925766 0.38 ENSMUST00000182269.1
ENSMUST00000183261.1
ENSMUST00000183074.1
ankyrin 3, epithelial
chr3_+_94643112 0.37 ENSMUST00000107276.1
predicted gene 10972
chr13_-_101692624 0.37 ENSMUST00000035532.6
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
chr3_+_5218546 0.37 ENSMUST00000026284.6
zinc finger homeodomain 4
chr3_-_122619663 0.36 ENSMUST00000162409.1
formin binding protein 1-like
chr11_-_61719946 0.36 ENSMUST00000151780.1
ENSMUST00000148584.1
solute carrier family 5 (sodium/glucose cotransporter), member 10
chr12_+_76081645 0.36 ENSMUST00000154509.1
spectrin repeat containing, nuclear envelope 2
chr15_-_100687908 0.36 ENSMUST00000023775.7
chymotrypsin-like elastase family, member 1
chr7_-_144939823 0.36 ENSMUST00000093962.4
cyclin D1
chr12_+_52516077 0.36 ENSMUST00000110725.1
Rho GTPase activating protein 5
chr4_+_102570065 0.35 ENSMUST00000097950.2
phosphodiesterase 4B, cAMP specific
chr15_-_13173607 0.35 ENSMUST00000036439.4
cadherin 6
chr4_+_125029992 0.35 ENSMUST00000030684.7
guanine nucleotide binding protein-like 2 (nucleolar)
chr8_+_44950208 0.35 ENSMUST00000098796.3
FAT tumor suppressor homolog 1 (Drosophila)
chr11_+_94044111 0.35 ENSMUST00000132079.1
sperm associated antigen 9
chr5_+_47984571 0.35 ENSMUST00000174313.1
slit homolog 2 (Drosophila)
chr3_-_97297778 0.35 ENSMUST00000181368.1
predicted gene, 17608
chr17_+_74338943 0.34 ENSMUST00000024869.6
spastin
chr9_+_51280295 0.34 ENSMUST00000050829.1
RIKEN cDNA 2010007H06 gene
chr19_+_40831296 0.34 ENSMUST00000119316.1
cyclin J
chr15_+_102977032 0.34 ENSMUST00000001706.6
homeobox C9
chr14_+_49172202 0.34 ENSMUST00000153488.1
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr16_+_93832121 0.34 ENSMUST00000044068.6
microrchidia 3
chr14_+_47663756 0.34 ENSMUST00000022391.7
kinectin 1
chr2_+_116067213 0.33 ENSMUST00000152412.1
RIKEN cDNA G630016G05 gene
chr19_+_55741884 0.33 ENSMUST00000111658.3
ENSMUST00000111654.1
transcription factor 7 like 2, T cell specific, HMG box
chr1_+_165788746 0.33 ENSMUST00000161559.2
CD247 antigen
chr3_+_109573907 0.33 ENSMUST00000106576.2
vav 3 oncogene
chr1_-_173367638 0.33 ENSMUST00000005470.4
ENSMUST00000111220.1
cell adhesion molecule 3
chr1_+_180641330 0.33 ENSMUST00000085804.5
lin-9 homolog (C. elegans)
chr13_+_14063776 0.33 ENSMUST00000129488.1
ENSMUST00000110536.1
ENSMUST00000110534.1
ENSMUST00000039538.8
ENSMUST00000110533.1
AT rich interactive domain 4B (RBP1-like)
chr2_-_180889660 0.32 ENSMUST00000137629.1
predicted gene 14342
chr3_+_145292472 0.32 ENSMUST00000029848.4
ENSMUST00000139001.1
collagen, type XXIV, alpha 1
chr17_+_53566971 0.32 ENSMUST00000000724.8
K(lysine) acetyltransferase 2B
chr15_-_8710734 0.32 ENSMUST00000005493.7
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr19_+_55742056 0.32 ENSMUST00000111659.2
transcription factor 7 like 2, T cell specific, HMG box
chr2_-_18048347 0.32 ENSMUST00000066885.5
SKI/DACH domain containing 1
chr13_+_37826904 0.32 ENSMUST00000149745.1
ras responsive element binding protein 1
chr7_-_74013676 0.32 ENSMUST00000026896.4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr19_-_14598031 0.31 ENSMUST00000167776.2
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr5_+_30232581 0.31 ENSMUST00000145167.1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr4_+_136310991 0.31 ENSMUST00000084219.5
heterogeneous nuclear ribonucleoprotein R
chr18_+_61555308 0.31 ENSMUST00000165721.1
ENSMUST00000115246.2
ENSMUST00000166990.1
ENSMUST00000163205.1
ENSMUST00000170862.1
casein kinase 1, alpha 1
chr1_+_59482133 0.31 ENSMUST00000114246.2
ENSMUST00000037105.6
frizzled homolog 7 (Drosophila)
chr4_-_83021102 0.31 ENSMUST00000071708.5
Fras1 related extracellular matrix protein 1
chr15_+_77084367 0.31 ENSMUST00000181870.1
RIKEN cDNA 1700109K24 gene
chr15_-_81408261 0.30 ENSMUST00000057236.3
DnaJ (Hsp40) homolog, subfamily B, member 7
chr15_-_66560997 0.30 ENSMUST00000048372.5
transmembrane protein 71
chr9_-_96752653 0.30 ENSMUST00000062899.3
RIKEN cDNA E030011O05 gene
chrX_+_18162575 0.30 ENSMUST00000044484.6
ENSMUST00000052368.8
lysine (K)-specific demethylase 6A
chr15_+_10952332 0.30 ENSMUST00000022853.8
ENSMUST00000110523.1
C1q and tumor necrosis factor related protein 3
chr2_+_55437100 0.30 ENSMUST00000112633.2
ENSMUST00000112632.1
potassium inwardly-rectifying channel, subfamily J, member 3
chr14_+_61607455 0.30 ENSMUST00000051184.8
potassium channel regulator
chr9_-_71896047 0.30 ENSMUST00000184448.1
transcription factor 12
chr3_-_53863764 0.29 ENSMUST00000122330.1
ENSMUST00000146598.1
ubiquitin-fold modifier 1
chr13_-_111490028 0.29 ENSMUST00000091236.4
GC-rich promoter binding protein 1
chr6_-_86733268 0.29 ENSMUST00000001185.7
germ cell-less homolog 1 (Drosophila)
chr4_-_24430838 0.29 ENSMUST00000183964.1
RP23-35K5.2
chr10_+_94036001 0.29 ENSMUST00000020208.4
FYVE, RhoGEF and PH domain containing 6
chr10_+_69925800 0.29 ENSMUST00000182029.1
ankyrin 3, epithelial
chr4_+_97777780 0.29 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
nuclear factor I/A
chr4_+_47208005 0.29 ENSMUST00000082303.6
ENSMUST00000102917.4
collagen, type XV, alpha 1
chr8_+_65967157 0.29 ENSMUST00000072482.6
membrane-associated ring finger (C3HC4) 1
chr16_+_78930940 0.29 ENSMUST00000114216.1
ENSMUST00000069148.6
ENSMUST00000023568.7
chondrolectin
chr5_+_77266196 0.29 ENSMUST00000113449.1
RE1-silencing transcription factor
chr6_+_54039558 0.28 ENSMUST00000046856.7
chimerin (chimaerin) 2
chr12_+_18514738 0.28 ENSMUST00000177778.1
ENSMUST00000063216.4
RIKEN cDNA 5730507C01 gene
chr1_+_16105774 0.28 ENSMUST00000027053.7
retinol dehydrogenase 10 (all-trans)
chr8_+_40511769 0.28 ENSMUST00000098817.2
vacuolar protein sorting 37A (yeast)
chr19_-_56822161 0.28 ENSMUST00000118592.1
RIKEN cDNA A630007B06 gene
chr4_+_136310936 0.28 ENSMUST00000131671.1
heterogeneous nuclear ribonucleoprotein R
chr16_-_91044473 0.28 ENSMUST00000118522.1
PAX3 and PAX7 binding protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Lef1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.7 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.4 1.2 GO:1901295 regulation of heart induction by regulation of canonical Wnt signaling pathway(GO:0090081) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.3 1.3 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.3 2.2 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.3 0.9 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.3 0.9 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.3 1.4 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.3 1.4 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.3 0.8 GO:0071676 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.2 1.3 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.2 0.6 GO:0006507 GPI anchor release(GO:0006507)
0.2 0.8 GO:0070295 renal water absorption(GO:0070295)
0.2 0.5 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.2 0.7 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.2 0.5 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.2 0.5 GO:1903537 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.1 1.4 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.1 1.7 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1 0.7 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.5 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.4 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.1 1.5 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.5 GO:0021564 vagus nerve development(GO:0021564)
0.1 1.7 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 0.4 GO:2000705 regulation of dense core granule biogenesis(GO:2000705)
0.1 0.8 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 0.2 GO:0002572 pro-T cell differentiation(GO:0002572)
0.1 1.0 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.1 1.0 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.6 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 0.3 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 3.5 GO:0060065 uterus development(GO:0060065)
0.1 0.2 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.1 2.2 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.1 0.3 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.1 0.6 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 0.3 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.1 0.6 GO:0072697 protein localization to cell cortex(GO:0072697)
0.1 0.3 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.1 0.6 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.5 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.1 0.2 GO:0044333 planar cell polarity pathway involved in axis elongation(GO:0003402) Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) mediolateral intercalation(GO:0060031) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775)
0.1 0.2 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.1 0.6 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.1 0.4 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.1 0.3 GO:0060431 primary lung bud formation(GO:0060431)
0.1 0.1 GO:0061144 alveolar secondary septum development(GO:0061144)
0.1 0.3 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076) positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 0.3 GO:0015801 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.1 0.6 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.5 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.2 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.2 GO:0015881 creatine transport(GO:0015881)
0.1 0.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 2.2 GO:0010107 potassium ion import(GO:0010107)
0.1 0.2 GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
0.1 0.2 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.1 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.4 GO:0051541 elastin metabolic process(GO:0051541)
0.1 0.3 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.1 0.4 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.1 1.1 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.3 GO:0070162 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163) negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.0 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.3 GO:0034214 axonal transport of mitochondrion(GO:0019896) protein hexamerization(GO:0034214)
0.0 0.2 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.0 0.3 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.3 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.6 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.3 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.5 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0 0.3 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.2 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.3 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.6 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.2 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.4 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.3 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.5 GO:0060789 hair follicle placode formation(GO:0060789)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.6 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.2 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.3 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.3 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.4 GO:0051531 NFAT protein import into nucleus(GO:0051531)
0.0 0.1 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.7 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.1 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245)
0.0 0.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.2 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.2 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.1 GO:1903972 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.0 0.2 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.9 GO:0061157 mRNA destabilization(GO:0061157)
0.0 1.4 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.5 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.4 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.2 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.2 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.4 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 0.1 GO:1902868 cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.3 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.3 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.2 GO:0010815 bradykinin catabolic process(GO:0010815) ubiquitin homeostasis(GO:0010992)
0.0 0.3 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.2 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.4 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 0.3 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.0 0.5 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.0 1.6 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.3 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.0 0.3 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.4 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 0.5 GO:0006301 postreplication repair(GO:0006301)
0.0 0.2 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 0.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.2 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.1 GO:0030910 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.0 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.2 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.3 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.1 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.3 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.0 GO:0090327 negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.0 0.1 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.3 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.1 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.0 0.2 GO:0045616 regulation of keratinocyte differentiation(GO:0045616)
0.0 0.2 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.1 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 0.1 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.0 0.3 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.3 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.1 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.8 GO:0008542 visual learning(GO:0008542)
0.0 0.0 GO:0050904 diapedesis(GO:0050904)
0.0 1.4 GO:0030879 mammary gland development(GO:0030879)
0.0 0.3 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.2 GO:0050930 induction of positive chemotaxis(GO:0050930)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.1 0.9 GO:0044305 calyx of Held(GO:0044305)
0.1 1.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 1.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.3 GO:0031417 NatC complex(GO:0031417)
0.1 1.3 GO:0097208 alveolar lamellar body(GO:0097208)
0.1 0.6 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.5 GO:0044094 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.1 0.4 GO:0098645 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 1.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.5 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.4 GO:0097413 Lewy body(GO:0097413)
0.0 0.2 GO:0002142 stereocilia ankle link complex(GO:0002142)
0.0 0.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 2.8 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.6 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 2.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.6 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.3 GO:0042581 specific granule(GO:0042581)
0.0 1.1 GO:0016235 aggresome(GO:0016235)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.7 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.0 0.3 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 2.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.7 GO:0097440 apical dendrite(GO:0097440)
0.0 0.2 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0071144 activin responsive factor complex(GO:0032444) SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 1.6 GO:0000922 spindle pole(GO:0000922)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 1.2 GO:0005581 collagen trimer(GO:0005581)
0.0 0.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.5 GO:0031901 early endosome membrane(GO:0031901)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.2 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.2 4.8 GO:0070411 I-SMAD binding(GO:0070411)
0.2 0.5 GO:0030350 iron-responsive element binding(GO:0030350)
0.1 0.7 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 1.2 GO:0048019 receptor antagonist activity(GO:0048019)
0.1 0.8 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.8 GO:0001851 complement component C3b binding(GO:0001851)
0.1 0.8 GO:0015288 porin activity(GO:0015288)
0.1 1.5 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.1 0.5 GO:0004594 pantothenate kinase activity(GO:0004594)
0.1 0.6 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 1.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.2 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 1.1 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 0.4 GO:0070012 oligopeptidase activity(GO:0070012)
0.1 0.6 GO:0043559 insulin binding(GO:0043559)
0.1 0.2 GO:0033680 ATP-dependent DNA/RNA helicase activity(GO:0033680)
0.1 0.4 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 2.2 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 1.4 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.3 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.1 0.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.2 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.1 0.6 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.1 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.3 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 1.1 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.0 0.3 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.5 GO:0015651 quaternary ammonium group transmembrane transporter activity(GO:0015651)
0.0 0.1 GO:0070905 serine binding(GO:0070905)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.3 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.1 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.2 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.2 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.6 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.4 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.3 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.6 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.3 GO:1901611 phosphatidylglycerol binding(GO:1901611)
0.0 0.6 GO:0070628 proteasome binding(GO:0070628)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.8 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.3 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 1.6 GO:0030507 spectrin binding(GO:0030507)
0.0 1.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.2 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.5 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 1.2 GO:0042805 actinin binding(GO:0042805)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.6 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.3 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.9 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 0.3 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.6 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.1 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.0 GO:0031699 beta-3 adrenergic receptor binding(GO:0031699)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 3.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 2.9 PID ARF6 PATHWAY Arf6 signaling events
0.1 1.9 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 1.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 2.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 4.9 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.0 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.5 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway
0.0 1.2 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 2.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.5 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.5 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 0.8 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 0.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 0.9 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 0.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 2.2 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 1.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 2.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 1.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.7 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.5 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.5 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.9 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.5 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.9 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.4 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR
0.0 1.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.0 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.1 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.7 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes