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GSE58827: Dynamics of the Mouse Liver

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Results for Ikzf2

Z-value: 0.80

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Transcription factors associated with Ikzf2

Gene Symbol Gene ID Gene Info
Ikzf2
ENSMUSG00000025997.7 IKAROS family zinc finger 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Ikzf2mm10_v2_chr1_-_69685937_696859660.492.4e-03Click!

Activity profile of Ikzf2 motif

Sorted Z-values of Ikzf2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_58394381 2.07 ENSMUST00000105468.1
Lims1
LIM and senescent cell antigen-like domains 1
chr7_-_134232005 2.04 ENSMUST00000134504.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr10_+_58394361 1.98 ENSMUST00000020077.4
Lims1
LIM and senescent cell antigen-like domains 1
chr19_-_59943000 1.97 ENSMUST00000170819.1
Rab11fip2
RAB11 family interacting protein 2 (class I)
chr3_-_116129615 1.94 ENSMUST00000029574.8
Vcam1
vascular cell adhesion molecule 1
chr7_-_134232125 1.73 ENSMUST00000127524.1
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr5_-_148392810 1.51 ENSMUST00000138257.1
Slc7a1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr4_-_44168252 1.49 ENSMUST00000145760.1
ENSMUST00000128426.1
Rnf38
ring finger protein 38
chr14_-_72709534 1.45 ENSMUST00000162478.1
Fndc3a
fibronectin type III domain containing 3A
chr9_+_124101944 1.41 ENSMUST00000171719.1
Ccr2
chemokine (C-C motif) receptor 2
chr8_-_122460666 1.34 ENSMUST00000006762.5
Snai3
snail homolog 3 (Drosophila)
chr9_+_124102110 1.32 ENSMUST00000168841.1
ENSMUST00000055918.6
Ccr2
chemokine (C-C motif) receptor 2
chr2_-_31116289 1.31 ENSMUST00000149196.1
Fnbp1
formin binding protein 1
chrX_+_107148927 1.26 ENSMUST00000147521.1
ENSMUST00000167673.1
A630033H20Rik
RIKEN cDNA A630033H20 gene
chr10_-_44458687 1.25 ENSMUST00000105490.2
Prdm1
PR domain containing 1, with ZNF domain
chr14_+_47663756 1.24 ENSMUST00000022391.7
Ktn1
kinectin 1
chr1_-_45503282 1.23 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chrX_+_157699113 1.17 ENSMUST00000112521.1
Smpx
small muscle protein, X-linked
chr8_+_45627946 1.17 ENSMUST00000145458.1
Sorbs2
sorbin and SH3 domain containing 2
chr8_-_80739497 1.15 ENSMUST00000043359.8
Smarca5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr2_-_72980402 1.06 ENSMUST00000066003.6
ENSMUST00000102689.3
Sp3
trans-acting transcription factor 3
chr6_-_128622872 1.06 ENSMUST00000171306.2
ENSMUST00000032512.8
Klrb1a
killer cell lectin-like receptor subfamily B member 1A
chr6_-_148831395 1.04 ENSMUST00000145960.1
Ipo8
importin 8
chr11_+_67200052 1.01 ENSMUST00000124516.1
ENSMUST00000018637.8
Myh1
myosin, heavy polypeptide 1, skeletal muscle, adult
chr16_-_75909272 1.01 ENSMUST00000114239.2
Samsn1
SAM domain, SH3 domain and nuclear localization signals, 1
chr5_-_123140135 1.00 ENSMUST00000160099.1
AI480526
expressed sequence AI480526
chr4_-_92191749 1.00 ENSMUST00000123179.1
Gm12666
predicted gene 12666
chr9_-_41157459 0.96 ENSMUST00000136530.1
Ubash3b
ubiquitin associated and SH3 domain containing, B
chr5_+_107437908 0.91 ENSMUST00000094541.2
Btbd8
BTB (POZ) domain containing 8
chr12_-_54999102 0.91 ENSMUST00000173529.1
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr13_-_103764502 0.89 ENSMUST00000074616.5
Srek1
splicing regulatory glutamine/lysine-rich protein 1
chr3_-_69859875 0.89 ENSMUST00000051239.7
ENSMUST00000171529.1
Sptssb
serine palmitoyltransferase, small subunit B
chrX_+_107149580 0.89 ENSMUST00000137107.1
ENSMUST00000067249.2
A630033H20Rik
RIKEN cDNA A630033H20 gene
chr9_+_53537021 0.88 ENSMUST00000035850.7
Npat
nuclear protein in the AT region
chr5_-_123141067 0.87 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
AI480526
expressed sequence AI480526
chr6_-_35133731 0.86 ENSMUST00000114993.2
ENSMUST00000114989.2
ENSMUST00000044163.6
Cnot4
CCR4-NOT transcription complex, subunit 4
chr4_-_44168339 0.84 ENSMUST00000045793.8
Rnf38
ring finger protein 38
chrX_+_106920618 0.83 ENSMUST00000060576.7
Lpar4
lysophosphatidic acid receptor 4
chr8_+_45628176 0.81 ENSMUST00000130850.1
Sorbs2
sorbin and SH3 domain containing 2
chr4_-_149698552 0.79 ENSMUST00000134534.1
ENSMUST00000146612.1
ENSMUST00000105688.3
Pik3cd
phosphatidylinositol 3-kinase catalytic delta polypeptide
chr10_-_19014549 0.79 ENSMUST00000146388.1
Tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr1_+_107511489 0.78 ENSMUST00000064916.2
Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr5_-_51567717 0.78 ENSMUST00000127135.1
ENSMUST00000151104.1
Ppargc1a
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr8_-_89147247 0.77 ENSMUST00000177870.1
Gm6625
predicted gene 6625
chr11_+_67200137 0.76 ENSMUST00000129018.1
Myh1
myosin, heavy polypeptide 1, skeletal muscle, adult
chr8_-_61591130 0.75 ENSMUST00000135439.1
ENSMUST00000121200.1
Palld
palladin, cytoskeletal associated protein
chr12_+_64965742 0.74 ENSMUST00000066296.7
Fam179b
family with sequence similarity 179, member B
chr12_-_64965496 0.73 ENSMUST00000021331.7
Klhl28
kelch-like 28
chr11_+_29463735 0.72 ENSMUST00000155854.1
Ccdc88a
coiled coil domain containing 88A
chr2_-_140671400 0.67 ENSMUST00000056760.3
Flrt3
fibronectin leucine rich transmembrane protein 3
chr15_+_60822947 0.66 ENSMUST00000180730.1
9930014A18Rik
RIKEN cDNA 9930014A18 gene
chr4_-_121215071 0.66 ENSMUST00000056635.5
Rlf
rearranged L-myc fusion sequence
chr2_+_103970115 0.64 ENSMUST00000111143.1
ENSMUST00000138815.1
Lmo2
LIM domain only 2
chr11_+_31872100 0.63 ENSMUST00000020543.6
ENSMUST00000109412.2
Cpeb4
cytoplasmic polyadenylation element binding protein 4
chr1_+_161494649 0.63 ENSMUST00000086084.1
Tnfsf18
tumor necrosis factor (ligand) superfamily, member 18
chr9_-_52168111 0.62 ENSMUST00000165519.1
Zc3h12c
zinc finger CCCH type containing 12C
chr10_-_44458715 0.62 ENSMUST00000039174.4
Prdm1
PR domain containing 1, with ZNF domain
chr2_-_7396192 0.60 ENSMUST00000137733.2
Celf2
CUGBP, Elav-like family member 2
chr13_-_76056996 0.59 ENSMUST00000056130.4
Gpr150
G protein-coupled receptor 150
chr2_+_103970221 0.58 ENSMUST00000111140.2
ENSMUST00000111139.2
Lmo2
LIM domain only 2
chr10_+_115817247 0.58 ENSMUST00000035563.7
ENSMUST00000080630.3
ENSMUST00000179196.1
Tspan8
tetraspanin 8
chrX_+_134601271 0.58 ENSMUST00000050331.6
ENSMUST00000059297.5
Hnrnph2
heterogeneous nuclear ribonucleoprotein H2
chr12_+_76324905 0.57 ENSMUST00000172992.1
Akap5
A kinase (PRKA) anchor protein 5
chr3_-_33844255 0.56 ENSMUST00000029222.5
Ccdc39
coiled-coil domain containing 39
chr13_+_83504032 0.56 ENSMUST00000163888.1
ENSMUST00000005722.7
Mef2c
myocyte enhancer factor 2C
chr13_+_44731281 0.55 ENSMUST00000174086.1
Jarid2
jumonji, AT rich interactive domain 2
chr2_-_7395968 0.55 ENSMUST00000002176.6
Celf2
CUGBP, Elav-like family member 2
chr3_-_61365951 0.55 ENSMUST00000066298.2
B430305J03Rik
RIKEN cDNA B430305J03 gene
chrX_+_107149454 0.54 ENSMUST00000125676.1
ENSMUST00000180182.1
A630033H20Rik
RIKEN cDNA A630033H20 gene
chr4_-_149698698 0.52 ENSMUST00000038859.7
ENSMUST00000105690.2
Pik3cd
phosphatidylinositol 3-kinase catalytic delta polypeptide
chr4_+_57637816 0.51 ENSMUST00000150412.1
Gm20459
predicted gene 20459
chrX_+_109095359 0.50 ENSMUST00000033598.8
Sh3bgrl
SH3-binding domain glutamic acid-rich protein like
chr6_-_128788486 0.50 ENSMUST00000172601.1
Klrb1c
killer cell lectin-like receptor subfamily B member 1C
chr8_-_67818284 0.48 ENSMUST00000120071.1
Psd3
pleckstrin and Sec7 domain containing 3
chr14_+_11227511 0.48 ENSMUST00000080237.3
Rpl21-ps4
ribosomal protein L21, pseudogene 4
chrX_+_164140447 0.47 ENSMUST00000073973.4
Ace2
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chrX_+_134601179 0.47 ENSMUST00000074950.4
ENSMUST00000113203.1
ENSMUST00000113202.1
Hnrnph2
heterogeneous nuclear ribonucleoprotein H2
chr6_+_92816460 0.44 ENSMUST00000057977.3
A730049H05Rik
RIKEN cDNA A730049H05 gene
chr8_+_45627709 0.43 ENSMUST00000134321.1
ENSMUST00000135336.1
Sorbs2
sorbin and SH3 domain containing 2
chr8_+_79028587 0.41 ENSMUST00000119254.1
Zfp827
zinc finger protein 827
chr18_+_65582390 0.41 ENSMUST00000169679.1
ENSMUST00000183326.1
Zfp532
zinc finger protein 532
chr14_+_54936456 0.40 ENSMUST00000037814.6
Cmtm5
CKLF-like MARVEL transmembrane domain containing 5
chr19_-_29812952 0.39 ENSMUST00000099525.3
Ranbp6
RAN binding protein 6
chr9_+_38752796 0.39 ENSMUST00000074740.2
Olfr920
olfactory receptor 920
chr6_-_128788598 0.39 ENSMUST00000167691.2
ENSMUST00000174404.1
Klrb1c
killer cell lectin-like receptor subfamily B member 1C
chr12_+_76324860 0.39 ENSMUST00000095610.2
ENSMUST00000154078.2
Akap5
A kinase (PRKA) anchor protein 5
chr10_+_25359798 0.38 ENSMUST00000053748.8
Epb4.1l2
erythrocyte protein band 4.1-like 2
chr15_-_83149270 0.38 ENSMUST00000129372.1
Poldip3
polymerase (DNA-directed), delta interacting protein 3
chr2_-_140671462 0.37 ENSMUST00000110057.2
Flrt3
fibronectin leucine rich transmembrane protein 3
chrX_-_153037549 0.37 ENSMUST00000051484.3
Mageh1
melanoma antigen, family H, 1
chr2_+_118900377 0.35 ENSMUST00000151162.1
Bahd1
bromo adjacent homology domain containing 1
chr5_+_110330697 0.33 ENSMUST00000112481.1
Pole
polymerase (DNA directed), epsilon
chr6_+_56714891 0.33 ENSMUST00000031805.8
Avl9
AVL9 homolog (S. cerevisiase)
chr6_+_59208870 0.31 ENSMUST00000062626.3
Tigd2
tigger transposable element derived 2
chr11_-_69801716 0.31 ENSMUST00000011285.4
ENSMUST00000102585.1
Fgf11
fibroblast growth factor 11
chr11_+_49523721 0.30 ENSMUST00000077143.4
Olfr1383
olfactory receptor 1383
chr2_-_26409100 0.30 ENSMUST00000114090.1
Inpp5e
inositol polyphosphate-5-phosphatase E
chr16_-_90727329 0.28 ENSMUST00000099554.4
Mis18a
MIS18 kinetochore protein homolog A (S. pombe)
chrX_+_112093496 0.28 ENSMUST00000130247.2
ENSMUST00000038546.6
Tex16
testis expressed gene 16
chr17_-_55915870 0.27 ENSMUST00000074828.4
Rpl21-ps6
ribosomal protein L21, pseudogene 6
chr19_+_55894508 0.25 ENSMUST00000142291.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr6_+_139621888 0.25 ENSMUST00000032353.8
Pik3c2g
phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide
chr7_+_36698002 0.24 ENSMUST00000021641.6
Tshz3
teashirt zinc finger family member 3
chr2_+_57997884 0.23 ENSMUST00000112616.1
ENSMUST00000166729.1
Galnt5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5
chr2_-_77170592 0.21 ENSMUST00000164114.2
ENSMUST00000049544.7
Ccdc141
coiled-coil domain containing 141
chr6_+_72549430 0.18 ENSMUST00000155705.1
Capg
capping protein (actin filament), gelsolin-like
chr2_+_97467657 0.18 ENSMUST00000059049.7
Lrrc4c
leucine rich repeat containing 4C
chr19_-_43388292 0.17 ENSMUST00000099428.3
Hpse2
heparanase 2
chr1_-_87394721 0.16 ENSMUST00000113212.3
Kcnj13
potassium inwardly-rectifying channel, subfamily J, member 13
chr2_-_26409161 0.16 ENSMUST00000145701.1
Inpp5e
inositol polyphosphate-5-phosphatase E
chr3_+_159839729 0.16 ENSMUST00000068952.5
Wls
wntless homolog (Drosophila)
chr16_-_95459245 0.16 ENSMUST00000176345.1
ENSMUST00000121809.2
ENSMUST00000118113.1
ENSMUST00000122199.1
Erg
avian erythroblastosis virus E-26 (v-ets) oncogene related
chrX_+_164373363 0.15 ENSMUST00000033751.7
Figf
c-fos induced growth factor
chr5_-_147076482 0.15 ENSMUST00000016664.7
Lnx2
ligand of numb-protein X 2
chr3_+_84925476 0.15 ENSMUST00000107675.1
Fbxw7
F-box and WD-40 domain protein 7
chr19_-_5688908 0.15 ENSMUST00000113615.2
Pcnxl3
pecanex-like 3 (Drosophila)
chr17_-_56571438 0.14 ENSMUST00000131056.1
Safb2
scaffold attachment factor B2
chr19_+_4214238 0.14 ENSMUST00000046506.6
Clcf1
cardiotrophin-like cytokine factor 1
chr5_-_88527841 0.13 ENSMUST00000087033.3
Igj
immunoglobulin joining chain
chr5_+_53590453 0.13 ENSMUST00000113865.1
Rbpj
recombination signal binding protein for immunoglobulin kappa J region
chr9_+_64385675 0.13 ENSMUST00000068967.4
Megf11
multiple EGF-like-domains 11
chr3_-_65529355 0.12 ENSMUST00000099076.3
4931440P22Rik
RIKEN cDNA 4931440P22 gene
chr5_+_53590215 0.11 ENSMUST00000037618.6
Rbpj
recombination signal binding protein for immunoglobulin kappa J region
chr14_-_54409469 0.11 ENSMUST00000000984.4
Slc7a7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr16_+_30065333 0.10 ENSMUST00000023171.7
Hes1
hairy and enhancer of split 1 (Drosophila)
chr6_+_127072902 0.10 ENSMUST00000000186.6
Fgf23
fibroblast growth factor 23
chr14_+_73510014 0.09 ENSMUST00000022705.5
Med4
mediator of RNA polymerase II transcription, subunit 4 homolog (yeast)
chr10_+_13966268 0.09 ENSMUST00000015645.4
Hivep2
human immunodeficiency virus type I enhancer binding protein 2
chr2_-_140671440 0.08 ENSMUST00000099301.1
Flrt3
fibronectin leucine rich transmembrane protein 3
chr2_+_72297895 0.08 ENSMUST00000144111.1
Zak
sterile alpha motif and leucine zipper containing kinase AZK
chr18_-_4352944 0.08 ENSMUST00000025078.2
Map3k8
mitogen-activated protein kinase kinase kinase 8
chr4_-_6990774 0.08 ENSMUST00000039987.3
Tox
thymocyte selection-associated high mobility group box
chr10_+_7667503 0.07 ENSMUST00000040135.8
Nup43
nucleoporin 43
chr11_+_70018728 0.07 ENSMUST00000018700.6
ENSMUST00000134376.2
Dlg4
discs, large homolog 4 (Drosophila)
chr8_+_120488416 0.06 ENSMUST00000034279.9
Gse1
genetic suppressor element 1
chr3_-_30509462 0.06 ENSMUST00000173899.1
Mecom
MDS1 and EVI1 complex locus
chrX_+_71556874 0.06 ENSMUST00000123100.1
Hmgb3
high mobility group box 3
chr19_+_41593363 0.05 ENSMUST00000099454.3
AI606181
expressed sequence AI606181
chr18_-_15151427 0.05 ENSMUST00000025992.6
Kctd1
potassium channel tetramerisation domain containing 1
chr7_-_70360593 0.03 ENSMUST00000032768.7
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr16_-_88774201 0.03 ENSMUST00000054223.2
2310057N15Rik
RIKEN cDNA 2310057N15 gene
chr4_+_117126776 0.02 ENSMUST00000134074.1
Tctex1d4
Tctex1 domain containing 4
chr6_+_72549252 0.02 ENSMUST00000114071.1
Capg
capping protein (actin filament), gelsolin-like
chr11_-_110251736 0.02 ENSMUST00000044003.7
Abca6
ATP-binding cassette, sub-family A (ABC1), member 6
chr19_-_41077106 0.01 ENSMUST00000087176.6
Opalin
oligodendrocytic myelin paranodal and inner loop protein
chr15_-_83149357 0.01 ENSMUST00000058793.6
Poldip3
polymerase (DNA-directed), delta interacting protein 3
chr11_-_55419898 0.00 ENSMUST00000108858.1
ENSMUST00000141530.1
Sparc
secreted acidic cysteine rich glycoprotein

Network of associatons between targets according to the STRING database.

First level regulatory network of Ikzf2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0002436 immune complex clearance by monocytes and macrophages(GO:0002436) astrocyte chemotaxis(GO:0035700) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451) regulation of astrocyte chemotaxis(GO:2000458)
0.6 1.9 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082)
0.5 4.1 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.4 1.1 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.3 1.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.3 0.8 GO:0002632 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573)
0.2 0.6 GO:2000328 regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.2 0.8 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.2 1.3 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.2 0.6 GO:0007521 muscle cell fate determination(GO:0007521) positive regulation of macrophage apoptotic process(GO:2000111)
0.2 1.0 GO:0036394 amylase secretion(GO:0036394)
0.1 0.7 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 1.9 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.1 0.2 GO:0035481 Notch signaling pathway involved in heart induction(GO:0003137) regulation of Notch signaling pathway involved in heart induction(GO:0035480) positive regulation of Notch signaling pathway involved in heart induction(GO:0035481)
0.1 1.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.5 GO:0015827 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.1 0.9 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.1 0.3 GO:0045004 DNA replication proofreading(GO:0045004)
0.1 1.2 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 1.5 GO:0015809 arginine transport(GO:0015809)
0.1 3.3 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1 0.6 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 0.7 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.7 GO:0015074 DNA integration(GO:0015074)
0.1 0.2 GO:0072194 kidney smooth muscle tissue development(GO:0072194)
0.1 0.9 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.6 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 1.0 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.1 0.2 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.0 0.3 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 1.4 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.1 GO:0043396 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.0 2.4 GO:0061049 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.1 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.8 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0021558 oculomotor nerve development(GO:0021557) trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of forebrain neuron differentiation(GO:2000978)
0.0 1.1 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 0.4 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.3 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.0 1.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.2 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.1 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.1 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 0.9 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 0.3 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:0060008 Sertoli cell differentiation(GO:0060008)
0.0 0.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.5 GO:0046855 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067) inositol phosphate dephosphorylation(GO:0046855)
0.0 2.0 GO:0035773 insulin secretion involved in cellular response to glucose stimulus(GO:0035773)
0.0 0.2 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.4 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.9 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.4 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.6 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0005588 collagen type V trimer(GO:0005588)
0.2 0.9 GO:0008623 CHRAC(GO:0008623)
0.1 0.9 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 1.5 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 0.9 GO:0005927 muscle tendon junction(GO:0005927)
0.1 0.9 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.1 1.0 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 0.3 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.1 0.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 1.8 GO:0032982 myosin filament(GO:0032982)
0.1 2.7 GO:0002102 podosome(GO:0002102)
0.1 1.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0097059 CRLF-CLCF1 complex(GO:0097058) CNTFR-CLCF1 complex(GO:0097059)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.3 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.5 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.1 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.8 GO:0097440 apical dendrite(GO:0097440)
0.0 0.4 GO:0000346 transcription export complex(GO:0000346)
0.0 2.2 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0090543 Flemming body(GO:0090543)
0.0 1.3 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.3 GO:0001669 acrosomal vesicle(GO:0001669)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.2 1.9 GO:0008131 primary amine oxidase activity(GO:0008131)
0.2 1.5 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.2 0.9 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.2 0.5 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.1 1.3 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 0.8 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.5 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 1.1 GO:0045499 chemorepellent activity(GO:0045499)
0.1 1.0 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 2.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.7 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.6 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.6 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0071820 N-box binding(GO:0071820)
0.0 3.5 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 1.4 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 1.2 GO:0070888 bHLH transcription factor binding(GO:0043425) E-box binding(GO:0070888)
0.0 1.0 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.2 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.2 GO:0019894 kinesin binding(GO:0019894)
0.0 0.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.5 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 4.1 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.3 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.8 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 1.0 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 1.0 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 1.9 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.7 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.2 3.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.8 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.9 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.0 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 1.0 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 1.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.8 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.2 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 3.8 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.3 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.8 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 1.0 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions