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GSE58827: Dynamics of the Mouse Liver

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Results for Hoxb8_Pdx1

Z-value: 1.26

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Transcription factors associated with Hoxb8_Pdx1

Gene Symbol Gene ID Gene Info
Hoxb8
ENSMUSG00000056648.4 homeobox B8
Pdx1
ENSMUSG00000029644.6 pancreatic and duodenal homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxb8mm10_v2_chr11_+_96282529_96282556-0.411.3e-02Click!
Pdx1mm10_v2_chr5_+_147269959_147270102-0.241.6e-01Click!

Activity profile of Hoxb8_Pdx1 motif

Sorted Z-values of Hoxb8_Pdx1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_130826762 17.70 ENSMUST00000133792.1
Pigr
polymeric immunoglobulin receptor
chr11_-_58613481 10.98 ENSMUST00000048801.7
2210407C18Rik
RIKEN cDNA 2210407C18 gene
chr13_-_23914998 9.97 ENSMUST00000021769.8
ENSMUST00000110407.2
Slc17a4
solute carrier family 17 (sodium phosphate), member 4
chr19_+_4711153 9.80 ENSMUST00000008991.6
Sptbn2
spectrin beta, non-erythrocytic 2
chr8_-_110039330 7.60 ENSMUST00000109222.2
Chst4
carbohydrate (chondroitin 6/keratan) sulfotransferase 4
chr6_-_89216237 7.44 ENSMUST00000079186.2
Gm839
predicted gene 839
chr6_+_124304646 6.95 ENSMUST00000112541.2
ENSMUST00000032234.2
Cd163
CD163 antigen
chr8_-_5105232 6.83 ENSMUST00000023835.1
Slc10a2
solute carrier family 10, member 2
chr7_-_46742979 6.79 ENSMUST00000128088.1
Saa1
serum amyloid A 1
chr7_+_46751832 5.79 ENSMUST00000075982.2
Saa2
serum amyloid A 2
chr7_+_131032061 5.61 ENSMUST00000084509.3
Dmbt1
deleted in malignant brain tumors 1
chr11_-_84167466 5.58 ENSMUST00000050771.7
Gm11437
predicted gene 11437
chr5_-_86926521 5.54 ENSMUST00000031183.2
Ugt2b1
UDP glucuronosyltransferase 2 family, polypeptide B1
chr11_-_49113757 5.51 ENSMUST00000060398.1
Olfr1396
olfactory receptor 1396
chrX_-_143933089 5.39 ENSMUST00000087313.3
Dcx
doublecortin
chr7_+_44384098 5.37 ENSMUST00000118962.1
ENSMUST00000118831.1
Syt3
synaptotagmin III
chr10_-_41709297 5.20 ENSMUST00000019955.9
ENSMUST00000099932.3
Ccdc162
coiled-coil domain containing 162
chr6_+_128662379 4.07 ENSMUST00000032518.4
Clec2h
C-type lectin domain family 2, member h
chr19_+_30232921 3.89 ENSMUST00000025797.5
Mbl2
mannose-binding lectin (protein C) 2
chr15_+_31224371 3.88 ENSMUST00000044524.9
Dap
death-associated protein
chr14_+_55560904 3.71 ENSMUST00000072530.4
ENSMUST00000128490.1
Dcaf11
DDB1 and CUL4 associated factor 11
chr1_+_88134786 3.60 ENSMUST00000113134.1
ENSMUST00000140092.1
Ugt1a6a
UDP glucuronosyltransferase 1 family, polypeptide A6A
chr10_+_21377290 3.52 ENSMUST00000042699.7
ENSMUST00000159163.1
Aldh8a1
aldehyde dehydrogenase 8 family, member A1
chr12_+_108334341 3.45 ENSMUST00000021684.4
Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr8_-_94696223 3.32 ENSMUST00000034227.4
Pllp
plasma membrane proteolipid
chr3_-_20275659 3.30 ENSMUST00000011607.5
Cpb1
carboxypeptidase B1 (tissue)
chr1_+_88103229 3.18 ENSMUST00000113135.3
ENSMUST00000113138.1
Ugt1a6a
Ugt1a6b
UDP glucuronosyltransferase 1 family, polypeptide A6A
UDP glucuronosyltransferase 1 family, polypeptide A6B
chr3_+_130617645 3.13 ENSMUST00000163620.1
Etnppl
ethanolamine phosphate phospholyase
chr5_-_87140318 3.11 ENSMUST00000067790.6
ENSMUST00000113327.1
Ugt2b5
UDP glucuronosyltransferase 2 family, polypeptide B5
chr14_+_55560480 3.10 ENSMUST00000121622.1
ENSMUST00000143431.1
ENSMUST00000150481.1
Dcaf11
DDB1 and CUL4 associated factor 11
chr13_+_4059565 3.10 ENSMUST00000041768.6
Akr1c14
aldo-keto reductase family 1, member C14
chr5_-_87424201 2.99 ENSMUST00000072818.5
Ugt2b38
UDP glucuronosyltransferase 2 family, polypeptide B38
chr1_-_82586781 2.97 ENSMUST00000087050.5
Col4a4
collagen, type IV, alpha 4
chr2_-_84775420 2.94 ENSMUST00000111641.1
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr3_+_130617448 2.91 ENSMUST00000166187.1
ENSMUST00000072271.6
Etnppl
ethanolamine phosphate phospholyase
chr18_-_31820413 2.88 ENSMUST00000165131.2
Gm6665
predicted gene 6665
chr2_-_177925604 2.87 ENSMUST00000108934.2
ENSMUST00000081529.4
C330013J21Rik
RIKEN cDNA C330013J21 gene
chr2_-_148045891 2.84 ENSMUST00000109964.1
Foxa2
forkhead box A2
chr9_-_70141484 2.84 ENSMUST00000034749.8
Fam81a
family with sequence similarity 81, member A
chr1_-_162866502 2.83 ENSMUST00000046049.7
Fmo1
flavin containing monooxygenase 1
chr1_-_162898484 2.78 ENSMUST00000143123.1
Fmo2
flavin containing monooxygenase 2
chr17_-_34804546 2.75 ENSMUST00000025223.8
Cyp21a1
cytochrome P450, family 21, subfamily a, polypeptide 1
chr2_-_84775388 2.74 ENSMUST00000023994.3
Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr3_+_62419668 2.69 ENSMUST00000161057.1
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr16_+_96361654 2.65 ENSMUST00000113794.1
Igsf5
immunoglobulin superfamily, member 5
chr2_+_126034967 2.57 ENSMUST00000110442.1
Fgf7
fibroblast growth factor 7
chr3_+_135281221 2.51 ENSMUST00000120397.1
ENSMUST00000171974.1
ENSMUST00000029817.7
Bdh2
3-hydroxybutyrate dehydrogenase, type 2
chr10_+_57784859 2.46 ENSMUST00000020024.5
Fabp7
fatty acid binding protein 7, brain
chr17_+_37193889 2.46 ENSMUST00000038844.6
Ubd
ubiquitin D
chr19_-_4498574 2.45 ENSMUST00000048482.6
2010003K11Rik
RIKEN cDNA 2010003K11 gene
chr3_-_107943705 2.44 ENSMUST00000106680.1
ENSMUST00000106684.1
ENSMUST00000106685.2
Gstm6
glutathione S-transferase, mu 6
chr16_+_56204313 2.41 ENSMUST00000160116.1
ENSMUST00000069936.7
Impg2
interphotoreceptor matrix proteoglycan 2
chr3_-_107943390 2.39 ENSMUST00000106681.1
Gstm6
glutathione S-transferase, mu 6
chr11_-_106580594 2.37 ENSMUST00000153870.1
Tex2
testis expressed gene 2
chr16_+_22951072 2.36 ENSMUST00000023590.8
Hrg
histidine-rich glycoprotein
chr5_-_130024280 2.32 ENSMUST00000161640.1
ENSMUST00000161884.1
ENSMUST00000161094.1
Asl
argininosuccinate lyase
chr13_+_23807027 2.30 ENSMUST00000006786.4
ENSMUST00000099697.2
Slc17a2
solute carrier family 17 (sodium phosphate), member 2
chr10_+_57784914 2.30 ENSMUST00000165013.1
Fabp7
fatty acid binding protein 7, brain
chr16_-_46155077 2.28 ENSMUST00000059524.5
Gm4737
predicted gene 4737
chr3_-_107943362 2.25 ENSMUST00000106683.1
Gstm6
glutathione S-transferase, mu 6
chr4_-_109202217 2.23 ENSMUST00000160774.1
ENSMUST00000030288.7
ENSMUST00000162787.2
Osbpl9
oxysterol binding protein-like 9
chr14_+_55559993 2.22 ENSMUST00000117236.1
Dcaf11
DDB1 and CUL4 associated factor 11
chr11_+_103103051 2.22 ENSMUST00000152971.1
Acbd4
acyl-Coenzyme A binding domain containing 4
chr18_-_10706688 2.19 ENSMUST00000002549.7
ENSMUST00000117726.1
ENSMUST00000117828.1
Abhd3
abhydrolase domain containing 3
chr5_-_89457763 2.16 ENSMUST00000049209.8
Gc
group specific component
chr15_+_87625214 2.12 ENSMUST00000068088.6
Fam19a5
family with sequence similarity 19, member A5
chr4_+_102589687 2.10 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b
phosphodiesterase 4B, cAMP specific
chr4_-_35157404 2.10 ENSMUST00000102975.3
Mob3b
MOB kinase activator 3B
chr1_+_88166004 2.07 ENSMUST00000097659.4
Ugt1a5
UDP glucuronosyltransferase 1 family, polypeptide A5
chr12_-_103904887 2.06 ENSMUST00000074051.5
Serpina1c
serine (or cysteine) peptidase inhibitor, clade A, member 1C
chr3_-_65392579 2.06 ENSMUST00000029414.5
Ssr3
signal sequence receptor, gamma
chrX_-_143933204 2.06 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx
doublecortin
chr12_-_103863551 2.05 ENSMUST00000085056.6
ENSMUST00000072876.5
ENSMUST00000124717.1
Serpina1a
serine (or cysteine) peptidase inhibitor, clade A, member 1A
chr14_+_55560010 2.03 ENSMUST00000147981.1
ENSMUST00000133256.1
Dcaf11
DDB1 and CUL4 associated factor 11
chr13_+_24802020 2.00 ENSMUST00000155575.1
BC005537
cDNA sequence BC005537
chr6_-_136875794 1.95 ENSMUST00000032342.1
Mgp
matrix Gla protein
chr2_-_160872552 1.94 ENSMUST00000103111.2
Zhx3
zinc fingers and homeoboxes 3
chr18_-_35498856 1.91 ENSMUST00000025215.8
Sil1
endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)
chr6_-_119388671 1.86 ENSMUST00000169744.1
Adipor2
adiponectin receptor 2
chr13_+_4233730 1.86 ENSMUST00000081326.6
Akr1c19
aldo-keto reductase family 1, member C19
chrX_-_36874111 1.84 ENSMUST00000047486.5
C330007P06Rik
RIKEN cDNA C330007P06 gene
chr19_+_45076105 1.84 ENSMUST00000026234.4
Kazald1
Kazal-type serine peptidase inhibitor domain 1
chr7_+_24257644 1.82 ENSMUST00000072713.6
Zfp108
zinc finger protein 108
chr5_+_43233928 1.81 ENSMUST00000114066.1
ENSMUST00000114065.1
Cpeb2
cytoplasmic polyadenylation element binding protein 2
chr2_-_86347764 1.79 ENSMUST00000099894.2
Olfr1055
olfactory receptor 1055
chr6_-_124542281 1.79 ENSMUST00000159463.1
ENSMUST00000162844.1
ENSMUST00000160505.1
ENSMUST00000162443.1
C1s
complement component 1, s subcomponent
chr1_-_9967932 1.70 ENSMUST00000185184.1
Tcf24
transcription factor 24
chr2_+_116067213 1.70 ENSMUST00000152412.1
G630016G05Rik
RIKEN cDNA G630016G05 gene
chr11_-_31671727 1.68 ENSMUST00000109415.1
Bod1
biorientation of chromosomes in cell division 1
chr6_-_21851914 1.67 ENSMUST00000134635.1
ENSMUST00000123116.1
ENSMUST00000120965.1
Tspan12
tetraspanin 12
chr13_-_85127514 1.67 ENSMUST00000179230.1
Gm4076
predicted gene 4076
chr6_-_83677807 1.64 ENSMUST00000037882.6
Cd207
CD207 antigen
chr3_+_66985647 1.63 ENSMUST00000162362.1
ENSMUST00000065074.7
Rsrc1
arginine/serine-rich coiled-coil 1
chr2_+_126034647 1.62 ENSMUST00000064794.7
Fgf7
fibroblast growth factor 7
chr4_+_102421518 1.61 ENSMUST00000106904.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr2_-_52676571 1.60 ENSMUST00000178799.1
Cacnb4
calcium channel, voltage-dependent, beta 4 subunit
chr11_+_104231390 1.60 ENSMUST00000106992.3
Mapt
microtubule-associated protein tau
chr16_-_37384915 1.59 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
Stxbp5l
syntaxin binding protein 5-like
chr5_+_92683625 1.59 ENSMUST00000168878.1
Shroom3
shroom family member 3
chr14_-_55560340 1.59 ENSMUST00000066106.3
A730061H03Rik
RIKEN cDNA A730061H03 gene
chr16_+_90738324 1.58 ENSMUST00000038197.2
Mrap
melanocortin 2 receptor accessory protein
chr10_+_4611971 1.57 ENSMUST00000105590.1
ENSMUST00000067086.7
Esr1
estrogen receptor 1 (alpha)
chr17_-_34862122 1.56 ENSMUST00000154526.1
Cfb
complement factor B
chr2_-_160872829 1.54 ENSMUST00000176141.1
Zhx3
zinc fingers and homeoboxes 3
chr5_+_43233463 1.53 ENSMUST00000169035.1
ENSMUST00000166713.1
Cpeb2
cytoplasmic polyadenylation element binding protein 2
chr3_+_66985700 1.53 ENSMUST00000046542.6
ENSMUST00000162693.1
Rsrc1
arginine/serine-rich coiled-coil 1
chr14_+_51007911 1.49 ENSMUST00000022424.6
Rnase10
ribonuclease, RNase A family, 10 (non-active)
chr17_-_34862473 1.47 ENSMUST00000025229.4
ENSMUST00000176203.2
ENSMUST00000128767.1
Cfb
complement factor B
chr3_-_65392546 1.46 ENSMUST00000119896.1
Ssr3
signal sequence receptor, gamma
chr9_+_40269202 1.46 ENSMUST00000114956.3
ENSMUST00000049941.5
Scn3b
sodium channel, voltage-gated, type III, beta
chr12_+_14494561 1.44 ENSMUST00000052528.3
Gm9847
predicted pseudogene 9847
chr8_+_118283719 1.44 ENSMUST00000117160.1
Cdh13
cadherin 13
chr2_+_125859134 1.42 ENSMUST00000028636.6
ENSMUST00000125084.1
Galk2
galactokinase 2
chr7_+_43995833 1.41 ENSMUST00000007156.4
Klk1b11
kallikrein 1-related peptidase b11
chr11_+_104231573 1.39 ENSMUST00000132977.1
ENSMUST00000132245.1
ENSMUST00000100347.4
Mapt
microtubule-associated protein tau
chr4_+_147492417 1.37 ENSMUST00000105721.2
Gm13152
predicted gene 13152
chr19_+_24875679 1.36 ENSMUST00000073080.5
Gm10053
predicted gene 10053
chr16_-_37384940 1.33 ENSMUST00000114781.1
ENSMUST00000114780.1
Stxbp5l
syntaxin binding protein 5-like
chr4_+_116596672 1.32 ENSMUST00000051869.7
Ccdc17
coiled-coil domain containing 17
chr1_+_10993452 1.30 ENSMUST00000027056.5
Prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr2_-_160872985 1.28 ENSMUST00000109460.1
ENSMUST00000127201.1
Zhx3
zinc fingers and homeoboxes 3
chr15_+_39006272 1.26 ENSMUST00000179165.1
ENSMUST00000022906.7
Fzd6
frizzled homolog 6 (Drosophila)
chr9_+_110880321 1.26 ENSMUST00000155014.1
Als2cl
ALS2 C-terminal like
chr10_-_89533550 1.25 ENSMUST00000105297.1
Nr1h4
nuclear receptor subfamily 1, group H, member 4
chr9_-_71163224 1.24 ENSMUST00000074465.2
Aqp9
aquaporin 9
chr1_+_93512079 1.24 ENSMUST00000120301.1
ENSMUST00000041983.4
ENSMUST00000122402.1
Farp2
FERM, RhoGEF and pleckstrin domain protein 2
chr1_-_164935522 1.23 ENSMUST00000027860.7
Xcl1
chemokine (C motif) ligand 1
chr3_+_65109343 1.20 ENSMUST00000159525.1
ENSMUST00000049230.8
Kcnab1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr10_+_4710119 1.20 ENSMUST00000105588.1
ENSMUST00000105589.1
Esr1
estrogen receptor 1 (alpha)
chr6_-_71262232 1.17 ENSMUST00000129630.2
ENSMUST00000114186.2
ENSMUST00000074301.3
Smyd1
SET and MYND domain containing 1
chrX_+_38600626 1.16 ENSMUST00000000365.2
Mcts1
malignant T cell amplified sequence 1
chr6_-_122282810 1.15 ENSMUST00000032207.8
Klrg1
killer cell lectin-like receptor subfamily G, member 1
chr7_+_6995443 1.14 ENSMUST00000086248.5
Aurkc
aurora kinase C
chr1_+_58713241 1.11 ENSMUST00000114309.1
ENSMUST00000069333.7
Cflar
CASP8 and FADD-like apoptosis regulator
chr14_+_74735641 1.10 ENSMUST00000177283.1
Esd
esterase D/formylglutathione hydrolase
chr13_-_48513394 1.10 ENSMUST00000177530.1
ENSMUST00000176996.1
ENSMUST00000176949.1
ENSMUST00000176176.1
Zfp169
zinc finger protein 169
chr11_+_72607221 1.09 ENSMUST00000021148.6
ENSMUST00000138247.1
Ube2g1
ubiquitin-conjugating enzyme E2G 1
chr9_+_40269273 1.09 ENSMUST00000176185.1
Scn3b
sodium channel, voltage-gated, type III, beta
chr3_+_94398517 1.09 ENSMUST00000050975.3
Lingo4
leucine rich repeat and Ig domain containing 4
chr6_+_37870786 1.09 ENSMUST00000120428.1
ENSMUST00000031859.7
Trim24
tripartite motif-containing 24
chr8_+_25808474 1.07 ENSMUST00000033979.4
Star
steroidogenic acute regulatory protein
chr3_-_116968969 1.07 ENSMUST00000143611.1
ENSMUST00000040097.7
Palmd
palmdelphin
chr9_-_70934808 1.06 ENSMUST00000034731.8
Lipc
lipase, hepatic
chr11_-_100822525 1.06 ENSMUST00000107358.2
Stat5b
signal transducer and activator of transcription 5B
chr11_-_69695802 1.05 ENSMUST00000108649.1
ENSMUST00000174159.1
ENSMUST00000181810.1
BC096441
Tnfsf12
cDNA sequence BC096441
tumor necrosis factor (ligand) superfamily, member 12
chr11_+_104231515 1.05 ENSMUST00000106993.3
Mapt
microtubule-associated protein tau
chr14_-_59365410 1.04 ENSMUST00000161031.1
ENSMUST00000160425.1
Phf11d
PHD finger protein 11D
chr6_-_28126125 1.04 ENSMUST00000115324.2
ENSMUST00000090512.3
Grm8
glutamate receptor, metabotropic 8
chr4_+_102254993 1.02 ENSMUST00000106908.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr7_-_101581161 1.02 ENSMUST00000063920.2
Art2b
ADP-ribosyltransferase 2b
chr5_+_31526989 1.02 ENSMUST00000114533.2
ENSMUST00000117262.1
ENSMUST00000117319.1
Slc4a1ap
solute carrier family 4 (anion exchanger), member 1, adaptor protein
chr4_-_42168603 1.01 ENSMUST00000098121.3
Gm13305
predicted gene 13305
chr4_+_145670685 1.01 ENSMUST00000105738.2
Gm13242
predicted gene 13242
chr17_+_64600702 1.00 ENSMUST00000086723.3
Man2a1
mannosidase 2, alpha 1
chr3_+_19957088 1.00 ENSMUST00000108328.1
Cp
ceruloplasmin
chr11_-_69695521 1.00 ENSMUST00000181261.1
Tnfsf12
tumor necrosis factor (ligand) superfamily, member 12
chrX_-_106011874 0.99 ENSMUST00000033583.7
ENSMUST00000151689.1
Magt1
magnesium transporter 1
chr17_-_40914350 0.99 ENSMUST00000166343.1
Glyatl3
glycine-N-acyltransferase-like 3
chr3_+_19957037 0.99 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
Cp
ceruloplasmin
chr18_+_56562443 0.98 ENSMUST00000130163.1
ENSMUST00000132628.1
Phax
phosphorylated adaptor for RNA export
chr8_-_67818284 0.98 ENSMUST00000120071.1
Psd3
pleckstrin and Sec7 domain containing 3
chr9_-_50739365 0.97 ENSMUST00000117093.1
ENSMUST00000121634.1
Dixdc1
DIX domain containing 1
chr2_-_164221605 0.97 ENSMUST00000018355.4
ENSMUST00000109376.2
Wfdc15b
WAP four-disulfide core domain 15B
chr3_-_57294880 0.95 ENSMUST00000171384.1
Tm4sf1
transmembrane 4 superfamily member 1
chr3_-_79145875 0.94 ENSMUST00000118340.1
Rapgef2
Rap guanine nucleotide exchange factor (GEF) 2
chr6_+_48554776 0.94 ENSMUST00000114545.1
ENSMUST00000153222.1
ENSMUST00000101436.2
Lrrc61
leucine rich repeat containing 61
chr11_-_69695753 0.94 ENSMUST00000180946.1
Tnfsf12
tumor necrosis factor (ligand) superfamily, member 12
chr13_-_4609122 0.94 ENSMUST00000110691.3
ENSMUST00000091848.5
Akr1e1
aldo-keto reductase family 1, member E1
chr13_-_48273865 0.94 ENSMUST00000180777.1
A330048O09Rik
RIKEN cDNA A330048O09 gene
chr19_+_20405280 0.94 ENSMUST00000179640.1
1500015L24Rik
RIKEN cDNA 1500015L24 gene
chr9_+_121710389 0.93 ENSMUST00000035113.9
Deb1
differentially expressed in B16F10 1
chrM_-_14060 0.93 ENSMUST00000082419.1
mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr5_+_106609098 0.91 ENSMUST00000167618.1
Gm17304
predicted gene, 17304
chr12_+_112588753 0.91 ENSMUST00000101029.2
Inf2
inverted formin, FH2 and WH2 domain containing
chr3_+_151437887 0.91 ENSMUST00000046977.7
Eltd1
EGF, latrophilin seven transmembrane domain containing 1
chrM_+_9452 0.90 ENSMUST00000082411.1
mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chr8_+_13435459 0.90 ENSMUST00000167071.1
ENSMUST00000167505.1
Tmem255b
transmembrane protein 255B
chr11_-_54249640 0.89 ENSMUST00000019060.5
Csf2
colony stimulating factor 2 (granulocyte-macrophage)
chr10_+_121365078 0.89 ENSMUST00000040344.6
Gns
glucosamine (N-acetyl)-6-sulfatase
chr2_-_125859139 0.89 ENSMUST00000110463.1
ENSMUST00000028635.5
Cops2
COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)
chr3_-_116712644 0.89 ENSMUST00000029569.2
Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chrX_-_73097017 0.89 ENSMUST00000114524.2
ENSMUST00000074619.5
Xlr3a
X-linked lymphocyte-regulated 3A
chr4_-_150003130 0.88 ENSMUST00000084117.6
H6pd
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr11_+_94327984 0.88 ENSMUST00000107818.2
ENSMUST00000051221.6
Ankrd40
ankyrin repeat domain 40
chr8_-_67818218 0.86 ENSMUST00000059374.4
Psd3
pleckstrin and Sec7 domain containing 3
chr5_-_66054499 0.86 ENSMUST00000145625.1
Rbm47
RNA binding motif protein 47
chr5_+_138363719 0.86 ENSMUST00000100526.2
Gm10874
predicted gene 10874
chr11_-_69696058 0.85 ENSMUST00000180587.1
ENSMUST00000094070.4
Tnfsf12
BC096441
tumor necrosis factor (ligand) superfamily, member 12
cDNA sequence BC096441
chr1_-_39577340 0.83 ENSMUST00000062525.5
Rnf149
ring finger protein 149
chr3_-_116968827 0.81 ENSMUST00000119557.1
Palmd
palmdelphin
chr17_+_55892184 0.81 ENSMUST00000054780.8
Zfp959
zinc finger protein 959
chr15_-_36496722 0.80 ENSMUST00000057486.7
Ankrd46
ankyrin repeat domain 46
chr9_+_54538984 0.80 ENSMUST00000060242.5
ENSMUST00000118413.1
Sh2d7
SH2 domain containing 7
chr7_-_49636847 0.80 ENSMUST00000032717.6
Dbx1
developing brain homeobox 1
chr10_-_18227473 0.79 ENSMUST00000174592.1
Ccdc28a
coiled-coil domain containing 28A
chrX_+_82948861 0.77 ENSMUST00000114000.1
Dmd
dystrophin, muscular dystrophy
chr5_-_38491948 0.77 ENSMUST00000129099.1
Slc2a9
solute carrier family 2 (facilitated glucose transporter), member 9
chr17_+_24426676 0.76 ENSMUST00000024946.5
Eci1
enoyl-Coenzyme A delta isomerase 1
chr14_-_59365465 0.76 ENSMUST00000095157.4
Phf11d
PHD finger protein 11D
chr8_-_83332416 0.75 ENSMUST00000177594.1
ENSMUST00000053902.3
Elmod2
ELMO/CED-12 domain containing 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxb8_Pdx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 17.7 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
2.5 7.6 GO:0042339 keratan sulfate metabolic process(GO:0042339)
1.9 5.7 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
1.8 5.5 GO:0018879 biphenyl metabolic process(GO:0018879)
1.4 4.2 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.9 2.8 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.8 8.8 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.8 2.4 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.8 2.3 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.6 4.2 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.6 3.9 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.5 2.8 GO:0072592 oxygen metabolic process(GO:0072592)
0.5 2.8 GO:0060011 Sertoli cell proliferation(GO:0060011) prostate epithelial cord elongation(GO:0060523)
0.4 4.0 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.4 1.3 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.4 3.3 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.4 1.2 GO:0006808 regulation of nitrogen utilization(GO:0006808) nitrogen utilization(GO:0019740) histone H3-R17 methylation(GO:0034971)
0.4 3.3 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.4 7.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.4 1.2 GO:0071663 immunoglobulin production in mucosal tissue(GO:0002426) granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663) positive regulation of thymocyte migration(GO:2000412) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538) regulation of T-helper 1 cell cytokine production(GO:2000554) positive regulation of T-helper 1 cell cytokine production(GO:2000556) positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.4 4.9 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.4 1.5 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.4 20.1 GO:0006953 acute-phase response(GO:0006953)
0.4 10.0 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.3 1.0 GO:0051030 snRNA transport(GO:0051030)
0.3 0.9 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.3 1.2 GO:0015855 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.3 3.9 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.3 5.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.3 1.2 GO:0002188 translation reinitiation(GO:0002188)
0.3 1.4 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.3 1.1 GO:1901740 skeletal muscle atrophy(GO:0014732) negative regulation of myoblast fusion(GO:1901740) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.3 1.1 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.3 6.8 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.3 1.1 GO:0070859 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.3 2.8 GO:0070995 NADPH oxidation(GO:0070995)
0.3 0.8 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.3 2.5 GO:0060373 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.3 3.5 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.2 4.8 GO:0060134 prepulse inhibition(GO:0060134)
0.2 3.0 GO:0032836 glomerular basement membrane development(GO:0032836)
0.2 0.2 GO:0098923 retrograde trans-synaptic signaling by soluble gas(GO:0098923)
0.2 0.6 GO:1990927 calcium ion regulated lysosome exocytosis(GO:1990927)
0.2 1.0 GO:0019364 pyridine nucleotide catabolic process(GO:0019364)
0.2 5.4 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.2 2.5 GO:0070842 aggresome assembly(GO:0070842)
0.2 3.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 2.8 GO:0042448 progesterone metabolic process(GO:0042448)
0.2 0.9 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.2 1.6 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2 0.9 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.2 0.5 GO:0002946 tRNA C5-cytosine methylation(GO:0002946)
0.2 0.4 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.2 0.5 GO:0036269 swimming behavior(GO:0036269)
0.2 0.5 GO:0060618 nipple development(GO:0060618)
0.2 1.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.2 1.1 GO:0071830 very-low-density lipoprotein particle remodeling(GO:0034372) chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.1 2.2 GO:0042359 vitamin D metabolic process(GO:0042359)
0.1 0.4 GO:0050955 thermoception(GO:0050955)
0.1 1.0 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 1.2 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.1 1.7 GO:0016322 neuron remodeling(GO:0016322)
0.1 1.8 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 1.4 GO:0006012 galactose metabolic process(GO:0006012)
0.1 1.9 GO:0006968 cellular defense response(GO:0006968)
0.1 1.9 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 12.8 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.1 1.0 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.4 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.1 0.7 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.1 0.3 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
0.1 0.3 GO:0019230 proprioception(GO:0019230)
0.1 0.8 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 1.1 GO:0051255 spindle midzone assembly(GO:0051255)
0.1 0.4 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 1.0 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1 0.4 GO:0006244 pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.1 2.1 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 0.5 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.1 2.5 GO:0019184 nonribosomal peptide biosynthetic process(GO:0019184)
0.1 0.9 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.3 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.1 3.9 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.1 0.2 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.1 2.0 GO:0046688 response to copper ion(GO:0046688)
0.1 0.7 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.1 0.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 1.8 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 2.2 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.1 0.5 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.8 GO:0046415 urate metabolic process(GO:0046415)
0.1 0.2 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841) positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1 0.2 GO:0002587 negative regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002587)
0.1 0.9 GO:0000338 protein deneddylation(GO:0000338)
0.0 1.0 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.9 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 3.8 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.3 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.5 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0 0.5 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.2 GO:0009227 UDP-N-acetylglucosamine catabolic process(GO:0006049) nucleotide-sugar catabolic process(GO:0009227)
0.0 0.9 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.4 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 3.5 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.4 GO:0046549 retinal cone cell development(GO:0046549)
0.0 1.9 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 1.2 GO:0010842 retina layer formation(GO:0010842)
0.0 1.8 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.1 GO:2000864 estradiol secretion(GO:0035938) regulation of estradiol secretion(GO:2000864)
0.0 1.6 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.3 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 1.6 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.2 GO:0060459 left lung development(GO:0060459) left lung morphogenesis(GO:0060460)
0.0 0.3 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.6 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.7 GO:0033273 response to vitamin(GO:0033273)
0.0 0.2 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.4 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.4 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.6 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.1 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 1.1 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.2 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.6 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.1 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.5 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.3 GO:2000269 regulation of fibroblast apoptotic process(GO:2000269)
0.0 0.4 GO:0045838 positive regulation of membrane potential(GO:0045838)
0.0 1.4 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 2.5 GO:0007601 visual perception(GO:0007601)
0.0 0.1 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.0 0.0 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.0 0.0 GO:0016132 brassinosteroid metabolic process(GO:0016131) brassinosteroid biosynthetic process(GO:0016132)
0.0 0.6 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.2 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.0 1.7 GO:0060606 neural tube closure(GO:0001843) tube closure(GO:0060606)
0.0 0.0 GO:0048936 neurofilament bundle assembly(GO:0033693) peripheral nervous system neuron axonogenesis(GO:0048936) response to sodium arsenite(GO:1903935)
0.0 0.4 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 0.7 GO:0051145 smooth muscle cell differentiation(GO:0051145)
0.0 0.8 GO:0050688 regulation of defense response to virus(GO:0050688)
0.0 0.2 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.2 GO:0035641 locomotory exploration behavior(GO:0035641)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 9.8 GO:0008091 spectrin(GO:0008091)
1.1 8.0 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.6 2.4 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.6 4.1 GO:0097418 neurofibrillary tangle(GO:0097418)
0.5 3.0 GO:0098651 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.4 17.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.4 2.8 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.4 13.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.3 11.1 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.2 0.7 GO:0036125 mitochondrial fatty acid beta-oxidation multienzyme complex(GO:0016507) fatty acid beta-oxidation multienzyme complex(GO:0036125)
0.2 1.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.2 4.9 GO:0000930 gamma-tubulin complex(GO:0000930)
0.2 1.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.2 0.7 GO:0030891 VCB complex(GO:0030891)
0.2 2.3 GO:0070852 cell body fiber(GO:0070852)
0.2 1.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 2.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.5 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 3.3 GO:0043218 compact myelin(GO:0043218)
0.1 0.3 GO:0048179 activin receptor complex(GO:0048179)
0.1 2.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.6 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 1.2 GO:1990635 proximal dendrite(GO:1990635)
0.1 13.2 GO:0072562 blood microparticle(GO:0072562)
0.1 0.5 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 0.5 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 6.8 GO:0000502 proteasome complex(GO:0000502)
0.1 1.0 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 1.8 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.4 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 1.1 GO:0030061 mitochondrial crista(GO:0030061)
0.1 0.6 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 1.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.0 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 1.0 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.8 GO:0031527 filopodium membrane(GO:0031527)
0.0 2.5 GO:0016235 aggresome(GO:0016235)
0.0 0.3 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.7 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 1.8 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 1.2 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 4.9 GO:0043296 apical junction complex(GO:0043296)
0.0 0.5 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 1.3 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.5 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.3 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 2.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 6.8 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.4 GO:0043196 varicosity(GO:0043196)
0.0 0.9 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.5 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.2 GO:0031209 SCAR complex(GO:0031209)
0.0 0.9 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.0 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 1.5 GO:0005901 caveola(GO:0005901)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.7 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 2.9 GO:0030426 growth cone(GO:0030426)
0.0 3.6 GO:0005938 cell cortex(GO:0005938)
0.0 3.6 GO:0005911 cell-cell junction(GO:0005911)
0.0 1.3 GO:0043679 axon terminus(GO:0043679)
0.0 1.4 GO:0043197 dendritic spine(GO:0043197)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 19.3 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0001533 cornified envelope(GO:0001533)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.0 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
1.8 17.7 GO:0019763 immunoglobulin receptor activity(GO:0019763)
1.3 7.6 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
1.0 6.8 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.9 12.3 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.9 2.8 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.8 2.5 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.8 5.3 GO:0005534 galactose binding(GO:0005534)
0.7 2.2 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.7 2.2 GO:1902271 D3 vitamins binding(GO:1902271)
0.7 3.3 GO:0055100 adiponectin binding(GO:0055100)
0.6 4.2 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.6 3.5 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.6 2.3 GO:0016842 amidine-lyase activity(GO:0016842)
0.6 4.0 GO:0099609 microtubule lateral binding(GO:0099609)
0.6 5.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.5 20.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.5 1.6 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.5 3.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.4 1.2 GO:0038181 bile acid receptor activity(GO:0038181)
0.4 1.1 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
0.4 2.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.4 1.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.3 9.0 GO:0042056 chemoattractant activity(GO:0042056)
0.3 0.9 GO:0047936 glucose 1-dehydrogenase [NAD(P)] activity(GO:0047936)
0.3 1.1 GO:0034056 estrogen response element binding(GO:0034056)
0.3 3.9 GO:0070513 death domain binding(GO:0070513)
0.3 3.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.3 4.1 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.3 13.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.2 1.2 GO:0015254 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.2 3.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 5.7 GO:0001848 complement binding(GO:0001848)
0.2 2.0 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 0.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 0.5 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.2 0.7 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508) long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.2 0.8 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.1 1.0 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.1 0.4 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 7.1 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 5.9 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.5 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.5 GO:0038100 nodal binding(GO:0038100)
0.1 2.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 3.5 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 0.9 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1 0.5 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 0.7 GO:0047035 alcohol dehydrogenase (NAD) activity(GO:0004022) testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 1.1 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 3.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 3.8 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 2.1 GO:0070628 proteasome binding(GO:0070628)
0.1 1.0 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.1 0.7 GO:0009374 biotin binding(GO:0009374)
0.1 4.8 GO:0005504 fatty acid binding(GO:0005504)
0.1 4.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 1.0 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 1.0 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 2.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.4 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 1.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 1.9 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.2 GO:0070402 NADPH binding(GO:0070402)
0.1 1.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.8 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.5 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.1 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 1.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.4 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 0.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.5 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.3 GO:0050694 galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.5 GO:0010181 FMN binding(GO:0010181)
0.0 0.8 GO:0017166 vinculin binding(GO:0017166)
0.0 2.8 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.4 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.3 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.4 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 1.1 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.4 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.6 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 5.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.9 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 1.2 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 2.0 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.3 GO:0000182 rDNA binding(GO:0000182)
0.0 1.1 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.5 GO:0005537 mannose binding(GO:0005537)
0.0 1.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 4.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 2.2 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 1.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 1.9 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 2.9 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 8.5 GO:0045296 cadherin binding(GO:0045296)
0.0 1.0 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.0 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.0 GO:0047598 sterol delta7 reductase activity(GO:0009918) 7-dehydrocholesterol reductase activity(GO:0047598)
0.0 0.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.2 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 3.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.5 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.4 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.0 0.7 GO:0030145 manganese ion binding(GO:0030145)
0.0 1.0 GO:0030414 peptidase inhibitor activity(GO:0030414)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.0 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 6.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 16.7 PID IL4 2PATHWAY IL4-mediated signaling events
0.2 7.1 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 3.0 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 1.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 5.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 3.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 2.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.2 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.9 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 9.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.4 PID AURORA B PATHWAY Aurora B signaling
0.0 0.5 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.4 PID REELIN PATHWAY Reelin signaling pathway
0.0 1.6 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 6.5 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.4 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.1 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.4 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.5 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.5 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.2 PID MYC PATHWAY C-MYC pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 6.8 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.7 5.7 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.4 3.0 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.3 3.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.3 6.8 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.3 12.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 5.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.2 4.1 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.2 2.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 4.0 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 3.2 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 5.0 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 4.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 1.1 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 1.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 0.9 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 7.4 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.1 3.8 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 2.0 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 0.8 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.5 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.0 0.4 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.7 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.1 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.5 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 2.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.9 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.6 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 1.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 2.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.9 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 1.0 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 2.3 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.8 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.5 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.1 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport