GSE58827: Dynamics of the Mouse Liver


Results for Hlx

Z-value: 0.24

Motif logo

Transcription factors associated with Hlx

Gene Symbol Gene ID Gene Info
ENSMUSG00000039377.6 H2.0-like homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot

Activity profile of Hlx motif

Sorted Z-values of Hlx motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_145032765 1.09 ENSMUST00000029919.5
chloride channel calcium activated 3
chrX_-_143933089 0.75 ENSMUST00000087313.3
chrX_-_143933204 0.40 ENSMUST00000112851.1
chr6_+_7555053 0.36 ENSMUST00000090679.2
tachykinin 1
chr7_-_45103747 0.23 ENSMUST00000003512.7
Fc receptor, IgG, alpha chain transporter
chr11_+_99873389 0.22 ENSMUST00000093936.3
keratin associated protein 9-1
chr9_+_54980880 0.20 ENSMUST00000093844.3
cholinergic receptor, nicotinic, alpha polypeptide 5
chr10_-_107486077 0.17 ENSMUST00000000445.1
myogenic factor 5
chr9_+_7571396 0.16 ENSMUST00000120900.1
matrix metallopeptidase 27
chr5_-_73632421 0.12 ENSMUST00000087177.2
leucine rich repeat containing 66
chr19_+_53944870 0.12 ENSMUST00000025932.7
soc-2 (suppressor of clear) homolog (C. elegans)
chrM_+_2743 0.10 ENSMUST00000082392.1
mitochondrially encoded NADH dehydrogenase 1
chr15_-_8710734 0.09 ENSMUST00000005493.7
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr10_+_102158858 0.09 ENSMUST00000138522.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr10_+_102159000 0.08 ENSMUST00000020039.6
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr3_+_32436376 0.07 ENSMUST00000108242.1
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr11_-_99244058 0.07 ENSMUST00000103132.3
keratin 222
chr2_+_78051155 0.06 ENSMUST00000145972.1
RIKEN cDNA 4930440I19 gene
chr19_-_53944621 0.06 ENSMUST00000135402.2
BBSome interacting protein 1
chr7_-_101837776 0.06 ENSMUST00000165052.1
inositol polyphosphate phosphatase-like 1
chr10_-_37138863 0.05 ENSMUST00000092584.5
myristoylated alanine rich protein kinase C substrate
chr1_+_180109192 0.05 ENSMUST00000143176.1
CDC42 binding protein kinase alpha
chr5_-_62766153 0.04 ENSMUST00000076623.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chrX_+_133850980 0.04 ENSMUST00000033602.8
chr5_+_121749196 0.02 ENSMUST00000161064.1
ataxin 2
chr15_-_8710409 0.00 ENSMUST00000157065.1
solute carrier family 1 (glial high affinity glutamate transporter), member 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Hlx

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:2000851 positive regulation of glucocorticoid secretion(GO:2000851)
0.1 1.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.2 GO:0035095 behavioral response to nicotine(GO:0035095)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.2 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.4 GO:0071855 neuropeptide receptor binding(GO:0071855)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors