GSE58827: Dynamics of the Mouse Liver


Results for Fubp1

Z-value: 0.60

Motif logo

Transcription factors associated with Fubp1

Gene Symbol Gene ID Gene Info
ENSMUSG00000028034.9 far upstream element (FUSE) binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot

Activity profile of Fubp1 motif

Sorted Z-values of Fubp1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_21780616 3.27 ENSMUST00000080511.2
histone cluster 1, H1b
chr11_+_44617310 2.86 ENSMUST00000081265.5
early B cell factor 1
chr2_+_103970115 2.19 ENSMUST00000111143.1
LIM domain only 2
chr2_+_103969528 2.03 ENSMUST00000123437.1
LIM domain only 2
chr2_+_103970221 1.97 ENSMUST00000111140.2
LIM domain only 2
chr10_-_88605017 1.94 ENSMUST00000119185.1
myosin binding protein C, slow-type
chr9_-_112187766 1.83 ENSMUST00000111872.2
cyclic AMP-regulated phosphoprotein, 21
chr2_-_32353247 1.64 ENSMUST00000078352.5
dynamin 1
chr11_+_67277124 1.60 ENSMUST00000019625.5
myosin, heavy polypeptide 8, skeletal muscle, perinatal
chr2_-_32353283 1.59 ENSMUST00000091089.5
dynamin 1
chr12_+_109545390 1.55 ENSMUST00000146701.1
maternally expressed 3
chr11_+_24076529 1.44 ENSMUST00000148087.1
predicted gene 12063
chr2_-_151009364 1.38 ENSMUST00000109896.1
chr1_+_156366037 1.29 ENSMUST00000102782.3
predicted gene 2000
chr19_-_47692042 1.23 ENSMUST00000026045.7
collagen, type XVII, alpha 1
chr11_+_96282648 1.10 ENSMUST00000168043.1
homeobox B8
chr4_+_123282778 1.09 ENSMUST00000106243.1
poly(A) binding protein, cytoplasmic 4
chr7_-_110862944 1.07 ENSMUST00000033050.3
lymphatic vessel endothelial hyaluronan receptor 1
chr18_-_70141568 1.06 ENSMUST00000121693.1
RAB27b, member RAS oncogene family
chr9_-_112187898 1.01 ENSMUST00000178410.1
cyclic AMP-regulated phosphoprotein, 21
chr18_-_34751502 1.01 ENSMUST00000060710.7
cell division cycle 25C
chr5_+_13399309 0.95 ENSMUST00000030714.7
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr11_+_67200052 0.93 ENSMUST00000124516.1
myosin, heavy polypeptide 1, skeletal muscle, adult
chr4_-_147642496 0.93 ENSMUST00000133006.1
RIKEN cDNA 2610305D13 gene
chr8_+_93810832 0.93 ENSMUST00000034198.8
guanine nucleotide binding protein, alpha O
chr10_+_14523062 0.89 ENSMUST00000096020.5
predicted gene 10335
chr5_+_110839973 0.88 ENSMUST00000066160.1
checkpoint kinase 2
chr16_-_92826004 0.87 ENSMUST00000023673.7
runt related transcription factor 1
chr2_-_72813665 0.86 ENSMUST00000136807.1
RIKEN cDNA 6430710C18 gene
chr14_+_11227511 0.86 ENSMUST00000080237.3
ribosomal protein L21, pseudogene 4
chrX_-_59567348 0.86 ENSMUST00000124402.1
fibroblast growth factor 13
chrX_-_59568068 0.83 ENSMUST00000119833.1
fibroblast growth factor 13
chr5_-_69542622 0.83 ENSMUST00000031045.6
Yip1 domain family, member 7
chr3_-_109027600 0.81 ENSMUST00000171143.1
family with sequence similarity 102, member B
chrX_-_106485214 0.80 ENSMUST00000039447.7
fibronectin type III domain containing 3C1
chr11_+_104550663 0.80 ENSMUST00000018800.2
myosin, light polypeptide 4
chr11_+_96282529 0.80 ENSMUST00000125410.1
homeobox B8
chr5_+_62813823 0.77 ENSMUST00000170704.1
predicted gene, 17384
chr6_-_135118240 0.77 ENSMUST00000032327.7
G protein-coupled receptor, family C, group 5, member D
chr7_-_116084635 0.77 ENSMUST00000111755.3
predicted gene 4353
chr3_+_87906321 0.74 ENSMUST00000005017.8
hepatoma-derived growth factor
chr6_-_129533267 0.74 ENSMUST00000181594.1
RIKEN cDNA 1700101I11 gene
chr14_-_98169542 0.69 ENSMUST00000069334.7
dachshund 1 (Drosophila)
chr10_+_53596936 0.68 ENSMUST00000020004.6
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr12_-_32208609 0.65 ENSMUST00000053215.7
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr12_+_69963452 0.61 ENSMUST00000110560.1
predicted gene 3086
chr18_+_34751803 0.61 ENSMUST00000181453.1
RIKEN cDNA 2010110K18 gene
chr5_+_120589003 0.59 ENSMUST00000069259.2
IQ motif containing D
chr2_-_127729872 0.59 ENSMUST00000028856.2
mal, T cell differentiation protein-like
chr11_-_68973840 0.59 ENSMUST00000038644.4
RAN guanine nucleotide release factor
chr10_-_128549102 0.58 ENSMUST00000176906.1
ribosomal protein L41
chr12_-_83984849 0.58 ENSMUST00000164935.2
predicted gene, 17673
chr5_-_135394499 0.57 ENSMUST00000065638.4
nuclear pore membrane protein 121
chr9_-_61372187 0.55 ENSMUST00000098658.2
predicted gene 10655
chr2_-_69206146 0.55 ENSMUST00000127243.1
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr17_-_24527925 0.55 ENSMUST00000176652.1
TNF receptor-associated factor 7
chr17_-_24527830 0.54 ENSMUST00000176353.1
TNF receptor-associated factor 7
chrX_+_163911401 0.54 ENSMUST00000140845.1
adaptor-related protein complex 1, sigma 2 subunit
chr18_-_77767752 0.54 ENSMUST00000048192.7
HAUS augmin-like complex, subunit 1
chr3_+_87906842 0.52 ENSMUST00000159492.1
hepatoma-derived growth factor
chr7_+_58658181 0.51 ENSMUST00000168747.1
ATPase, class V, type 10A
chr5_-_124354671 0.51 ENSMUST00000031341.4
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr11_-_102319093 0.50 ENSMUST00000174302.1
upstream binding transcription factor, RNA polymerase I
chr18_+_35536539 0.48 ENSMUST00000081864.3
predicted pseudogene 5239
chrX_+_94636066 0.48 ENSMUST00000096368.3
G1 to S phase transition 2
chr17_+_35049966 0.47 ENSMUST00000007257.9
chloride intracellular channel 1
chr19_+_53140430 0.46 ENSMUST00000111741.2
adducin 3 (gamma)
chr2_-_156992021 0.44 ENSMUST00000109558.1
N-myc downstream regulated gene 3
chr2_+_104069819 0.43 ENSMUST00000111131.2
CD59b antigen
chr17_+_27057288 0.42 ENSMUST00000049308.8
inositol 1,4,5-triphosphate receptor 3
chr6_+_134920401 0.41 ENSMUST00000067327.4
cyclin-dependent kinase inhibitor 1B
chr9_+_109875541 0.41 ENSMUST00000094324.3
cell division cycle 25A
chr4_+_147361303 0.41 ENSMUST00000133078.1
predicted gene 13145
chr4_-_94650092 0.40 ENSMUST00000107101.1
leucine rich repeat containing 19
chr6_+_83165920 0.39 ENSMUST00000077407.5
dynactin 1
chr3_+_122924353 0.38 ENSMUST00000106429.3
RIKEN cDNA 1810037I17 gene
chr5_-_73632421 0.38 ENSMUST00000087177.2
leucine rich repeat containing 66
chr14_+_51129055 0.37 ENSMUST00000095923.3
ribonuclease, RNase A family, 6
chr1_-_173277756 0.37 ENSMUST00000111224.3
mucosal pentraxin 2
chr2_+_111378967 0.37 ENSMUST00000062407.2
olfactory receptor 1284
chr19_+_4192129 0.34 ENSMUST00000046094.4
protein phosphatase 1, catalytic subunit, alpha isoform
chr10_-_53630439 0.33 ENSMUST00000075540.5
minichromosome maintenance complex component 9
chr2_-_45110336 0.33 ENSMUST00000028229.6
zinc finger E-box binding homeobox 2
chr2_-_69206133 0.32 ENSMUST00000112320.1
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr3_+_84952146 0.32 ENSMUST00000029727.7
F-box and WD-40 domain protein 7
chr17_-_44736648 0.30 ENSMUST00000113572.2
runt related transcription factor 2
chr11_+_99857915 0.30 ENSMUST00000107434.1
predicted gene 11568
chr4_-_11965699 0.30 ENSMUST00000108301.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr2_+_10372426 0.29 ENSMUST00000114864.2
Scm-like with four mbt domains 2
chr13_-_78196373 0.29 ENSMUST00000125176.2
nuclear receptor subfamily 2, group F, member 1
chr18_-_31911903 0.28 ENSMUST00000054984.6
SFT2 domain containing 3
chr5_+_147430153 0.28 ENSMUST00000031651.8
PAN3 polyA specific ribonuclease subunit homolog (S. cerevisiae)
chr13_-_96435952 0.28 ENSMUST00000181761.1
ankyrin repeat and death domain containing 1B
chr19_-_40994133 0.26 ENSMUST00000117695.1
B cell linker
chr1_-_154725920 0.25 ENSMUST00000004214.8
calcium channel, voltage-dependent, R type, alpha 1E subunit
chr1_+_34005872 0.25 ENSMUST00000182296.1
chr4_+_109343029 0.24 ENSMUST00000030281.5
epidermal growth factor receptor pathway substrate 15
chr6_+_17307632 0.24 ENSMUST00000115453.1
caveolin 1, caveolae protein
chr4_-_55532453 0.23 ENSMUST00000132746.1
Kruppel-like factor 4 (gut)
chr8_+_66386292 0.22 ENSMUST00000039540.5
membrane-associated ring finger (C3HC4) 1
chr17_+_26252903 0.22 ENSMUST00000025023.7
Luc7 homolog (S. cerevisiae)-like
chr5_+_48242549 0.21 ENSMUST00000172493.1
slit homolog 2 (Drosophila)
chr12_-_91590009 0.21 ENSMUST00000021345.6
general transcription factor II A, 1
chr1_+_107361929 0.21 ENSMUST00000027566.2
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 11
chr15_+_77084367 0.20 ENSMUST00000181870.1
RIKEN cDNA 1700109K24 gene
chr7_+_75643223 0.20 ENSMUST00000137959.1
A kinase (PRKA) anchor protein 13
chr1_+_153905301 0.20 ENSMUST00000105679.3
RIKEN cDNA A930039A15 gene
chr11_+_4895328 0.20 ENSMUST00000038237.1
THO complex 5
chr2_+_65845767 0.20 ENSMUST00000122912.1
cysteine-serine-rich nuclear protein 3
chr11_+_4895316 0.19 ENSMUST00000101615.2
THO complex 5
chr12_+_3365108 0.18 ENSMUST00000020999.5
kinesin family member 3C
chr12_+_87954475 0.18 ENSMUST00000181843.1
predicted gene 2042
chrX_-_103623648 0.18 ENSMUST00000156211.1
Ftx transcript, Xist regulator (non-protein coding)
chr2_+_88817173 0.17 ENSMUST00000072057.1
olfactory receptor 1202
chr18_+_86711059 0.17 ENSMUST00000068423.3
cerebellin 2 precursor protein
chr9_+_61372359 0.17 ENSMUST00000178113.1
transducin-like enhancer of split 3, homolog of Drosophila E(spl)
chrX_-_103623704 0.16 ENSMUST00000130063.1
Ftx transcript, Xist regulator (non-protein coding)
chr19_-_56548013 0.16 ENSMUST00000182059.1
DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)
chr19_-_56548122 0.16 ENSMUST00000026063.5
DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)
chr1_-_134955908 0.16 ENSMUST00000045665.6
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr7_+_103184803 0.16 ENSMUST00000106893.1
olfactory receptor 592
chr15_+_78983041 0.15 ENSMUST00000109687.1
TRIO and F-actin binding protein
chr19_+_44562841 0.15 ENSMUST00000040455.4
hypoxia-inducible factor 1, alpha subunit inhibitor
chr13_+_119462752 0.15 ENSMUST00000026519.8
RIKEN cDNA 4833420G17 gene
chr3_+_14480692 0.15 ENSMUST00000037321.7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 12
chr4_-_94650134 0.14 ENSMUST00000053419.2
leucine rich repeat containing 19
chr3_+_96629919 0.14 ENSMUST00000048915.6
RNA binding motif protein 8a
chr10_+_94576254 0.13 ENSMUST00000117929.1
transmembrane and coiled coil domains 3
chr14_+_61599493 0.12 ENSMUST00000039562.6
tripartite motif-containing 13
chr19_+_8617991 0.12 ENSMUST00000010250.2
solute carrier family 22 (organic anion transporter), member 6
chr5_-_110269816 0.11 ENSMUST00000059229.9
phosphoglycerate mutase family member 5
chr9_+_106821874 0.11 ENSMUST00000159645.1
Vpr (HIV-1) binding protein
chr1_-_138175126 0.11 ENSMUST00000183301.1
protein tyrosine phosphatase, receptor type, C
chr1_-_138175238 0.11 ENSMUST00000182536.1
protein tyrosine phosphatase, receptor type, C
chr4_+_133369702 0.10 ENSMUST00000030669.7
solute carrier family 9 (sodium/hydrogen exchanger), member 1
chr17_-_27204357 0.10 ENSMUST00000055117.7
LEM domain containing 2
chr17_+_26252915 0.10 ENSMUST00000114976.2
Luc7 homolog (S. cerevisiae)-like
chr5_+_66968416 0.10 ENSMUST00000038188.7
LIM and calponin homology domains 1
chr19_+_12798574 0.09 ENSMUST00000025601.6
chr12_+_35925620 0.09 ENSMUST00000042101.4
anterior gradient 3
chr1_+_174430430 0.09 ENSMUST00000053178.4
olfactory receptor 414
chr5_-_5266038 0.08 ENSMUST00000115451.1
cyclin-dependent kinase 14
chr4_-_118409219 0.08 ENSMUST00000075406.5
seizure threshold 2
chr2_-_151476153 0.08 ENSMUST00000080132.2
RIKEN cDNA 4921509C19 gene
chr10_+_39420009 0.08 ENSMUST00000157009.1
Fyn proto-oncogene
chr5_-_145010643 0.07 ENSMUST00000110673.1
karyopherin alpha 7 (importin alpha 8)
chr5_-_32854185 0.07 ENSMUST00000130134.2
proline rich 14-like
chr2_-_42653598 0.07 ENSMUST00000052550.6
low density lipoprotein-related protein 1B (deleted in tumors)
chr10_-_33624587 0.07 ENSMUST00000160299.1
clavesin 2
chr3_+_138352378 0.07 ENSMUST00000090166.4
alcohol dehydrogenase 6B (class V)
chr5_+_135369942 0.06 ENSMUST00000000940.8
NOL1/NOP2/Sun domain family, member 5
chr8_+_21938352 0.06 ENSMUST00000076786.2
defensin beta 35
chr2_+_104590453 0.06 ENSMUST00000028599.7
cleavage stimulation factor, 3' pre-RNA, subunit 3
chr11_-_69681903 0.05 ENSMUST00000066760.1
SUMO/sentrin specific peptidase 3
chr5_+_88487982 0.05 ENSMUST00000031222.8
chr5_+_122391878 0.04 ENSMUST00000102525.4
actin related protein 2/3 complex, subunit 3
chr4_+_146514920 0.04 ENSMUST00000140089.1
predicted gene 13247
chr7_+_6961160 0.03 ENSMUST00000054055.6
ubiquitin specific peptidase 29
chr15_+_102954427 0.03 ENSMUST00000001701.3
homeobox C11
chr1_-_134955847 0.03 ENSMUST00000168381.1
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr4_+_118409331 0.02 ENSMUST00000084319.4
mediator of RNA polymerase II transcription, subunit 8 homolog (yeast)
chr10_+_50895651 0.02 ENSMUST00000020071.3
single-minded homolog 1 (Drosophila)
chr9_+_88839164 0.02 ENSMUST00000163255.2
tripartite motif-containing 43C
chr8_-_60954726 0.01 ENSMUST00000110302.1
chloride channel 3
chr16_-_94370647 0.01 ENSMUST00000113910.1
phosphatidylinositol glycan anchor biosynthesis, class P
chr7_+_31059342 0.01 ENSMUST00000039775.7
leucine-rich repeat LGI family, member 4
chr11_-_107348130 0.01 ENSMUST00000134763.1
phosphatidylinositol transfer protein, cytoplasmic 1
chr4_-_101893789 0.01 ENSMUST00000051043.3
RIKEN cDNA C130073F10 gene
chr6_-_113377510 0.01 ENSMUST00000099118.2
transcriptional adaptor 3
chr2_+_65845833 0.00 ENSMUST00000053910.3
cysteine-serine-rich nuclear protein 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Fubp1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.2 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.4 6.2 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.3 0.9 GO:0098763 mitotic cell cycle phase(GO:0098763)
0.3 0.9 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
0.3 2.3 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.2 1.0 GO:1903375 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.2 1.1 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.2 0.5 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.7 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 1.9 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 1.6 GO:0030049 muscle filament sliding(GO:0030049)
0.1 0.7 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.1 0.6 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.1 1.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 1.9 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 0.4 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.1 0.6 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.2 GO:0071676 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.1 0.4 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.1 0.3 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.1 0.4 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.1 1.1 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.1 0.4 GO:0001905 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
0.1 0.2 GO:0014900 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900) negative regulation of interleukin-8 biosynthetic process(GO:0045415)
0.1 0.5 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.1 0.3 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 1.5 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 0.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.3 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.0 0.5 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.2 GO:2000473 immunoglobulin biosynthetic process(GO:0002378) regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.0 1.4 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 0.3 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 2.8 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.1 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.0 0.3 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.6 GO:0006999 nuclear pore organization(GO:0006999)
0.0 3.3 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.2 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.8 GO:0031424 keratinization(GO:0031424)
0.0 0.9 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.1 GO:0044821 telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.6 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.1 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.1 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.4 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.0 GO:0042488 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) regulation of enamel mineralization(GO:0070173)
0.0 1.0 GO:0061515 myeloid cell development(GO:0061515)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.2 0.6 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.2 0.5 GO:0018444 translation release factor complex(GO:0018444)
0.1 1.6 GO:0032982 myosin filament(GO:0032982)
0.1 0.9 GO:0031262 Ndc80 complex(GO:0031262)
0.1 3.2 GO:0043196 varicosity(GO:0043196)
0.1 2.9 GO:0005859 muscle myosin complex(GO:0005859)
0.1 0.3 GO:0031251 PAN complex(GO:0031251)
0.1 1.5 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.5 GO:0070652 HAUS complex(GO:0070652)
0.1 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 3.3 GO:0000786 nucleosome(GO:0000786)
0.0 0.4 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.4 GO:0005869 dynactin complex(GO:0005869)
0.0 1.0 GO:0031672 A band(GO:0031672)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 2.0 GO:0014704 intercalated disc(GO:0014704)
0.0 1.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.2 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 1.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 7.0 GO:0005667 transcription factor complex(GO:0005667)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.2 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.1 0.9 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 2.9 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 0.7 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 6.5 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 0.4 GO:0000822 inositol hexakisphosphate binding(GO:0000822) inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 1.9 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 0.5 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1 0.3 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 1.2 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.5 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 1.6 GO:0000146 microfilament motor activity(GO:0000146)
0.1 0.6 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.1 1.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.2 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.0 0.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 1.1 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 1.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 2.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 1.1 GO:0031489 myosin V binding(GO:0031489)
0.0 0.3 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.3 GO:0050733 RS domain binding(GO:0050733)
0.0 0.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 1.0 GO:0050699 WW domain binding(GO:0050699)
0.0 0.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0031404 chloride ion binding(GO:0031404)
0.0 2.5 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.4 GO:0070840 dynein complex binding(GO:0070840)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 0.9 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 2.3 PID ATM PATHWAY ATM pathway
0.0 0.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.4 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.2 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.4 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.5 PID ALK1 PATHWAY ALK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.2 1.9 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.2 3.2 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 4.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.0 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 0.4 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.6 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 3.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 1.8 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.3 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.9 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.6 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 1.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.2 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases