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GSE58827: Dynamics of the Mouse Liver
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Results for Foxo4
Z-value: 0.62
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Transcription factors associated with Foxo4
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Foxo4 | mm10_v2_chrX_+_101254528_101254574 | -0.16 | 3.6e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr11_-_102107822 Show fit | 1.62 |
ENSMUST00000177304.1
ENSMUST00000017455.8 |
peptide YY |
|
| chr10_-_109010955 Show fit | 1.57 |
ENSMUST00000105276.1
ENSMUST00000064054.7 |
synaptotagmin I |
|
| chr18_-_38918642 Show fit | 1.30 |
ENSMUST00000040647.4
|
fibroblast growth factor 1 |
|
| chr13_-_106547060 Show fit | 1.12 |
ENSMUST00000076359.2
|
DPH3B, KTI11 homolog B (S. cerevisiae), pseudogene |
|
| chr19_-_5796924 Show fit | 1.02 |
ENSMUST00000174808.1
|
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) |
|
| chr2_-_175931051 Show fit | 1.00 |
ENSMUST00000108949.2
ENSMUST00000109018.2 |
predicted gene 8898 |
|
| chr7_-_4524229 Show fit | 0.99 |
ENSMUST00000154913.1
|
troponin I, cardiac 3 |
|
| chr4_-_61835185 Show fit | 0.97 |
ENSMUST00000082287.2
|
major urinary protein 5 |
|
| chr6_+_56714891 Show fit | 0.93 |
ENSMUST00000031805.8
|
AVL9 homolog (S. cerevisiase) |
|
| chr10_-_83337440 Show fit | 0.92 |
ENSMUST00000126617.1
|
solute carrier family 41, member 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Foxo4
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.6 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.1 | 1.6 | GO:0032096 | negative regulation of response to food(GO:0032096) |
| 0.3 | 1.3 | GO:1901509 | regulation of endothelial tube morphogenesis(GO:1901509) |
| 0.2 | 1.0 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 0.2 | 1.0 | GO:0001980 | regulation of systemic arterial blood pressure by ischemic conditions(GO:0001980) |
| 0.2 | 0.9 | GO:0002282 | microglial cell activation involved in immune response(GO:0002282) positive regulation of interferon-alpha biosynthetic process(GO:0045356) |
| 0.1 | 0.7 | GO:0098870 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.0 | 0.6 | GO:0061436 | establishment of skin barrier(GO:0061436) |
| 0.0 | 0.6 | GO:0006471 | protein ADP-ribosylation(GO:0006471) |
| 0.0 | 0.5 | GO:0014029 | neural crest formation(GO:0014029) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.6 | GO:0031045 | dense core granule(GO:0031045) |
| 0.2 | 1.0 | GO:1990584 | cardiac Troponin complex(GO:1990584) |
| 0.0 | 0.7 | GO:0044292 | dendrite terminus(GO:0044292) |
| 0.0 | 0.5 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.0 | 0.5 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.0 | 0.4 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.0 | 0.3 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.0 | 0.2 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.7 | GO:0005550 | pheromone binding(GO:0005550) |
| 0.4 | 1.6 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 0.1 | 1.6 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.1 | 1.3 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.1 | 1.0 | GO:0030172 | troponin C binding(GO:0030172) |
| 0.0 | 0.7 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.0 | 0.7 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.0 | 0.7 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.1 | 0.6 | GO:0004887 | thyroid hormone receptor activity(GO:0004887) |
| 0.0 | 0.6 | GO:0003956 | NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.6 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.0 | 1.3 | PID FGF PATHWAY | FGF signaling pathway |
| 0.0 | 0.9 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.3 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
| 0.1 | 1.6 | REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
| 0.1 | 1.3 | REACTOME FGFR4 LIGAND BINDING AND ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
| 0.0 | 1.0 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.1 | 0.9 | REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
| 0.0 | 0.9 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 0.0 | 0.4 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 0.3 | REACTOME PHOSPHORYLATION OF THE APC C | Genes involved in Phosphorylation of the APC/C |