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GSE58827: Dynamics of the Mouse Liver

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Results for Fos

Z-value: 1.84

Motif logo

Transcription factors associated with Fos

Gene Symbol Gene ID Gene Info
ENSMUSG00000021250.7 FBJ osteosarcoma oncogene

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Fosmm10_v2_chr12_+_85473883_854738960.555.0e-04Click!

Activity profile of Fos motif

Sorted Z-values of Fos motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_102365111 20.64 ENSMUST00000006749.9
solute carrier family 4 (anion exchanger), member 1
chr2_+_84734050 18.20 ENSMUST00000090729.2
yippee-like 4 (Drosophila)
chr1_-_132390301 18.10 ENSMUST00000132435.1
transmembrane and coiled-coil domains 2
chr14_+_80000292 16.34 ENSMUST00000088735.3
olfactomedin 4
chr7_-_45920830 15.60 ENSMUST00000164119.1
epithelial membrane protein 3
chr7_+_24370255 15.47 ENSMUST00000171904.1
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr1_+_174172738 15.45 ENSMUST00000027817.7
spectrin alpha, erythrocytic 1
chr11_+_116533257 12.66 ENSMUST00000154034.1
sphingosine kinase 1
chr11_+_116531744 12.60 ENSMUST00000106387.2
ENSMUST00000100201.3
sphingosine kinase 1
chr7_+_110772604 11.82 ENSMUST00000005829.6
adenosine monophosphate deaminase 3
chr3_-_88503187 11.44 ENSMUST00000120377.1
lamin A
chr13_+_95696851 10.55 ENSMUST00000022182.4
coagulation factor II (thrombin) receptor-like 2
chr11_-_53480178 10.50 ENSMUST00000104955.2
sosondowah ankyrin repeat domain family member A
chr4_-_140774196 10.45 ENSMUST00000026381.6
peptidyl arginine deiminase, type IV
chr7_-_143502515 10.01 ENSMUST00000010904.4
pleckstrin homology-like domain, family A, member 2
chr7_-_126369543 9.95 ENSMUST00000032997.6
linker for activation of T cells
chr7_+_78914216 9.68 ENSMUST00000120331.2
interferon-stimulated protein
chr3_-_88503331 9.67 ENSMUST00000029699.6
lamin A
chr19_-_34166037 9.33 ENSMUST00000025686.7
ankyrin repeat domain 22
chr2_+_13573927 9.19 ENSMUST00000141365.1
ENSMUST00000028062.2
vimentin
chr17_-_57194170 9.13 ENSMUST00000005976.6
tumor necrosis factor (ligand) superfamily, member 14
chr3_-_123034943 9.11 ENSMUST00000029761.7
myozenin 2
chr7_+_78913765 9.00 ENSMUST00000038142.8
interferon-stimulated protein
chr9_+_51213683 8.87 ENSMUST00000034554.7
POU domain, class 2, associating factor 1
chr8_+_94984399 8.84 ENSMUST00000093271.6
G protein-coupled receptor 56
chr1_+_107511489 8.60 ENSMUST00000064916.2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chrX_-_104671048 8.53 ENSMUST00000042070.5
zinc finger, DHHC domain containing 15
chr13_-_21780616 8.49 ENSMUST00000080511.2
histone cluster 1, H1b
chr1_+_107511416 8.47 ENSMUST00000009356.4
serine (or cysteine) peptidase inhibitor, clade B, member 2
chrX_-_143827391 8.46 ENSMUST00000087316.5
calpain 6
chr6_+_4755327 8.46 ENSMUST00000176551.1
paternally expressed 10
chr2_+_24336846 7.86 ENSMUST00000114487.2
interleukin 1 receptor antagonist
chr10_+_88091070 7.81 ENSMUST00000048621.7
pro-melanin-concentrating hormone
chr2_-_102451792 7.73 ENSMUST00000099678.3
four jointed box 1 (Drosophila)
chr7_-_126799134 7.62 ENSMUST00000087566.4
aldolase A, fructose-bisphosphate
chr1_+_40515362 7.36 ENSMUST00000027237.5
interleukin 18 receptor accessory protein
chr5_+_31116722 7.29 ENSMUST00000114637.1
tripartite motif-containing 54
chr7_-_126799163 7.07 ENSMUST00000032934.5
aldolase A, fructose-bisphosphate
chr2_+_164948219 7.06 ENSMUST00000017881.2
matrix metallopeptidase 9
chr5_+_31116702 7.04 ENSMUST00000013771.8
tripartite motif-containing 54
chr11_-_100207507 6.85 ENSMUST00000007272.7
keratin 14
chr1_+_170277376 6.81 ENSMUST00000179976.1
SH2 domain protein 1B1
chr3_+_103102604 6.59 ENSMUST00000173206.1
DENN/MADD domain containing 2C
chr5_-_134946917 6.37 ENSMUST00000051401.2
claudin 4
chr11_+_69125896 6.34 ENSMUST00000021268.2
arachidonate lipoxygenase 3
chr4_-_43040279 6.33 ENSMUST00000107958.1
ENSMUST00000107959.1
ENSMUST00000152846.1
family with sequence similarity 214, member B
chr8_+_88289028 6.25 ENSMUST00000171456.1
adenylate cyclase 7
chrX_-_134583114 6.24 ENSMUST00000113213.1
ENSMUST00000033617.6
Bruton agammaglobulinemia tyrosine kinase
chr8_-_25091341 6.08 ENSMUST00000125466.1
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr19_+_53460610 5.96 ENSMUST00000180442.1
RIKEN cDNA 4833407H14 gene
chr7_+_30776394 5.96 ENSMUST00000041703.7
dermokine
chr5_-_65091584 5.94 ENSMUST00000043352.4
transmembrane protein 156
chr10_+_128909866 5.90 ENSMUST00000026407.7
CD63 antigen
chr13_-_90905321 5.70 ENSMUST00000109541.3
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr7_+_30787897 5.67 ENSMUST00000098559.1
keratinocyte differentiation associated protein
chr14_-_54712139 5.65 ENSMUST00000064290.6
CCAAT/enhancer binding protein (C/EBP), epsilon
chr18_+_82910863 5.30 ENSMUST00000171238.1
zinc finger protein 516
chr17_-_47834682 5.18 ENSMUST00000066368.6
MyoD family inhibitor
chr1_-_52190901 5.13 ENSMUST00000156887.1
ENSMUST00000129107.1
glutaminase
chr13_+_76579670 5.09 ENSMUST00000126960.1
ENSMUST00000109583.2
multiple C2 domains, transmembrane 1
chr6_+_49036518 5.06 ENSMUST00000031840.7
glycoprotein (transmembrane) nmb
chr4_+_43506966 4.97 ENSMUST00000030183.3
carbonic anhydrase 9
chr11_-_100135928 4.91 ENSMUST00000107411.2
keratin 15
chr6_-_129507107 4.78 ENSMUST00000183258.1
ENSMUST00000182784.1
ENSMUST00000032265.6
ENSMUST00000162815.1
oxidized low density lipoprotein (lectin-like) receptor 1
chr12_+_80518990 4.74 ENSMUST00000021558.6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr9_+_78615501 4.72 ENSMUST00000093812.4
CD109 antigen
chr5_+_34999111 4.70 ENSMUST00000114283.1
regulator of G-protein signaling 12
chr7_-_109781538 4.64 ENSMUST00000033331.6
nuclear receptor interacting protein 3
chr3_+_109573907 4.62 ENSMUST00000106576.2
vav 3 oncogene
chr3_+_95929325 4.61 ENSMUST00000171368.1
ENSMUST00000168106.1
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr16_+_78930940 4.59 ENSMUST00000114216.1
ENSMUST00000069148.6
ENSMUST00000023568.7
chondrolectin
chr11_+_50357759 4.56 ENSMUST00000052596.2
chibby homolog 3 (Drosophila)
chr11_-_79059872 4.56 ENSMUST00000141409.1
kinase suppressor of ras 1
chr5_+_34999046 4.55 ENSMUST00000114281.1
regulator of G-protein signaling 12
chr2_+_156475844 4.54 ENSMUST00000103135.1
erythrocyte protein band 4.1-like 1
chr3_+_95929246 4.53 ENSMUST00000165307.1
ENSMUST00000015893.6
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr6_+_135362931 4.53 ENSMUST00000032330.9
epithelial membrane protein 1
chr15_-_9529868 4.49 ENSMUST00000003981.4
interleukin 7 receptor
chrX_-_7671341 4.47 ENSMUST00000033486.5
proteolipid protein 2
chr17_+_35049966 4.47 ENSMUST00000007257.9
chloride intracellular channel 1
chr15_-_64312636 4.41 ENSMUST00000177083.1
ENSMUST00000177371.1
ArfGAP with SH3 domain, ankyrin repeat and PH domain1
chr2_+_156475803 4.41 ENSMUST00000029155.8
erythrocyte protein band 4.1-like 1
chr14_-_34588654 4.39 ENSMUST00000022328.6
ENSMUST00000064098.6
ENSMUST00000022327.5
ENSMUST00000022330.7
LIM domain binding 3
chrX_+_159840463 4.34 ENSMUST00000112451.1
ENSMUST00000112453.2
SH3-domain kinase binding protein 1
chrX_-_48454152 4.31 ENSMUST00000114958.1
E74-like factor 4 (ets domain transcription factor)
chr9_+_69453620 4.28 ENSMUST00000034756.8
ENSMUST00000123470.1
annexin A2
chr10_+_119992916 4.28 ENSMUST00000105261.2
glutamate receptor interacting protein 1
chrX_+_96455359 4.27 ENSMUST00000033553.7
hephaestin
chr3_+_14641722 4.25 ENSMUST00000029071.8
carbonic anhydrase 13
chr17_+_46161021 4.24 ENSMUST00000024748.7
ENSMUST00000172170.1
GTP binding protein 2
chrX_-_160906998 4.22 ENSMUST00000069417.5
gap junction protein, alpha 6
chr12_+_103388656 4.20 ENSMUST00000101094.2
ENSMUST00000021620.6
OTU domain, ubiquitin aldehyde binding 2
chr14_-_33185489 4.19 ENSMUST00000159606.1
WD repeat and FYVE domain containing 4
chr13_-_23991158 4.17 ENSMUST00000021770.7
secretagogin, EF-hand calcium binding protein
chr16_-_92826004 4.15 ENSMUST00000023673.7
runt related transcription factor 1
chr5_+_34999070 4.09 ENSMUST00000114280.1
regulator of G-protein signaling 12
chr10_+_80930071 4.03 ENSMUST00000015456.8
growth arrest and DNA-damage-inducible 45 beta
chr5_-_24392012 4.03 ENSMUST00000059401.6
autophagy related 9B
chr1_-_58973421 3.97 ENSMUST00000173590.1
ENSMUST00000027186.5
trafficking protein, kinesin binding 2
chr11_-_76509419 3.97 ENSMUST00000094012.4
active BCR-related gene
chr1_+_171559186 3.96 ENSMUST00000004829.7
CD244 natural killer cell receptor 2B4
chrX_-_7740206 3.91 ENSMUST00000128289.1
coiled-coil domain containing 120
chr11_-_109473598 3.88 ENSMUST00000070152.5
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr7_+_30763750 3.87 ENSMUST00000165887.1
ENSMUST00000085691.4
ENSMUST00000085688.4
ENSMUST00000054427.6
dermokine
chr1_+_135783065 3.81 ENSMUST00000132795.1
troponin I, skeletal, slow 1
chr4_-_43558386 3.79 ENSMUST00000130353.1
talin 1
chr11_-_100261021 3.78 ENSMUST00000080893.6
keratin 17
chr4_+_150927918 3.75 ENSMUST00000139826.1
ENSMUST00000116257.1
tumor necrosis factor receptor superfamily, member 9
chr10_+_119992962 3.75 ENSMUST00000154238.1
glutamate receptor interacting protein 1
chr3_-_92485886 3.74 ENSMUST00000054599.7
small proline-rich protein 1A
chr2_-_166581969 3.70 ENSMUST00000109246.1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr5_+_105415738 3.66 ENSMUST00000112707.1
leucine rich repeat containing 8 family, member B
chr14_-_33185066 3.64 ENSMUST00000061753.8
ENSMUST00000130509.2
WD repeat and FYVE domain containing 4
chr4_+_109406623 3.61 ENSMUST00000124209.1
tetratricopeptide repeat domain 39A
chr1_-_153186447 3.61 ENSMUST00000027753.6
laminin, gamma 2
chr8_+_21529031 3.59 ENSMUST00000084041.3
predicted gene 15308
chr8_+_21391811 3.54 ENSMUST00000120874.3
predicted gene, 21002
chr6_+_42350000 3.48 ENSMUST00000164375.1
zyxin
chr8_+_69902178 3.48 ENSMUST00000050373.5
testis-specific serine kinase 6
chr11_+_61684419 3.45 ENSMUST00000093019.5
family with sequence similarity 83, member G
chr8_+_122282117 3.35 ENSMUST00000054052.8
zinc finger protein, multitype 1
chr17_+_12119274 3.35 ENSMUST00000024594.2
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr16_+_35770382 3.34 ENSMUST00000023555.4
Hspb associated protein 1
chr6_-_129533267 3.32 ENSMUST00000181594.1
RIKEN cDNA 1700101I11 gene
chr17_+_28951950 3.29 ENSMUST00000153462.1
potassium channel tetramerisation domain containing 20
chr13_-_55528511 3.26 ENSMUST00000047877.4
docking protein 3
chr16_-_44558864 3.26 ENSMUST00000023370.4
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr8_+_21378560 3.13 ENSMUST00000170275.2
defensin, alpha, 2
chr6_+_42349826 3.12 ENSMUST00000070635.6
zyxin
chr15_-_90679307 3.08 ENSMUST00000014777.8
ENSMUST00000064391.5
copine VIII
chr7_+_27486910 3.03 ENSMUST00000008528.7
SERTA domain containing 1
chr11_+_78188422 3.02 ENSMUST00000002128.7
ENSMUST00000150941.1
RAB34, member of RAS oncogene family
chr7_+_92741603 2.96 ENSMUST00000032879.7
RAB30, member RAS oncogene family
chr18_+_44071390 2.96 ENSMUST00000068473.2
serine peptidase inhibitor, Kazal type 6
chr13_-_62858364 2.94 ENSMUST00000021907.7
fructose bisphosphatase 2
chr7_+_126776939 2.93 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
yippee-like 3 (Drosophila)
chr8_-_11008458 2.93 ENSMUST00000040514.6
insulin receptor substrate 2
chr10_+_116143881 2.86 ENSMUST00000105271.2
protein tyrosine phosphatase, receptor type, R
chr5_+_30013141 2.85 ENSMUST00000026845.7
interleukin 6
chr7_+_126766397 2.80 ENSMUST00000032944.7
glycerophosphodiester phosphodiesterase domain containing 3
chr2_+_118663235 2.79 ENSMUST00000099557.3
p21 protein (Cdc42/Rac)-activated kinase 6
chrX_+_71962971 2.78 ENSMUST00000048790.6
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr7_+_126584937 2.78 ENSMUST00000039522.6
apolipoprotein B receptor
chr2_+_30441831 2.78 ENSMUST00000131476.1
protein phosphatase 2A, regulatory subunit B (PR 53)
chr5_+_25247344 2.68 ENSMUST00000114950.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11
chr1_+_135232045 2.68 ENSMUST00000110798.3
predicted gene 4204
chr14_+_79515618 2.68 ENSMUST00000110835.1
E74-like factor 1
chr2_+_131909951 2.66 ENSMUST00000124100.1
ENSMUST00000136783.1
prion protein gene complex (Prn), transcript variant 1, mRNA
chrX_-_167209149 2.66 ENSMUST00000112176.1
thymosin, beta 4, X chromosome
chr4_+_133130505 2.66 ENSMUST00000084241.5
ENSMUST00000138831.1
WAS protein family, member 2
chr7_-_142372210 2.57 ENSMUST00000084412.5
interferon induced transmembrane protein 10
chr16_-_44558879 2.49 ENSMUST00000114634.1
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr12_-_54999102 2.49 ENSMUST00000173529.1
bromodomain adjacent to zinc finger domain 1A
chr8_+_69822429 2.48 ENSMUST00000164890.1
ENSMUST00000034325.4
lysophosphatidic acid receptor 2
chr17_+_35841668 2.48 ENSMUST00000174124.1
mediator of DNA damage checkpoint 1
chr1_+_165302625 2.45 ENSMUST00000111450.1
G protein-coupled receptor 161
chr7_+_30751471 2.45 ENSMUST00000182229.1
ENSMUST00000182227.1
ENSMUST00000080518.6
ENSMUST00000182721.1
suprabasin
chr3_+_95232287 2.43 ENSMUST00000107200.1
ENSMUST00000107199.1
CDC42 small effector 1
chr5_+_100846364 2.42 ENSMUST00000092990.3
ENSMUST00000145612.1
1-acylglycerol-3-phosphate O-acyltransferase 9
chr11_-_33843526 2.41 ENSMUST00000065970.5
ENSMUST00000109340.2
Kv channel-interacting protein 1
chr9_-_112187766 2.38 ENSMUST00000111872.2
ENSMUST00000164754.2
cyclic AMP-regulated phosphoprotein, 21
chr1_-_165160773 2.38 ENSMUST00000027859.5
T-box 19
chr8_+_95703037 2.38 ENSMUST00000073139.7
ENSMUST00000080666.7
N-myc downstream regulated gene 4
chr7_-_126594941 2.37 ENSMUST00000058429.5
interleukin 27
chr5_+_100846130 2.37 ENSMUST00000112887.1
ENSMUST00000031255.8
1-acylglycerol-3-phosphate O-acyltransferase 9
chr16_-_29946499 2.31 ENSMUST00000181968.1
predicted gene, 26569
chr11_+_67798269 2.30 ENSMUST00000168612.1
ENSMUST00000040574.4
dehydrogenase/reductase (SDR family) member 7C
chr3_-_107518001 2.30 ENSMUST00000169449.1
ENSMUST00000029499.8
solute carrier family 6 (neurotransmitter transporter), member 17
chr13_+_15463837 2.22 ENSMUST00000110510.3
GLI-Kruppel family member GLI3
chr3_+_103576081 2.21 ENSMUST00000183637.1
ENSMUST00000117221.2
ENSMUST00000118117.1
ENSMUST00000118563.2
synaptotagmin VI
chr10_+_111473186 2.17 ENSMUST00000065917.8
nucleosome assembly protein 1-like 1
chr19_-_56389877 2.15 ENSMUST00000166203.1
ENSMUST00000167239.1
ENSMUST00000040711.8
ENSMUST00000095947.4
ENSMUST00000073536.6
nebulin-related anchoring protein
chr11_+_78188806 2.14 ENSMUST00000056241.5
RAB34, member of RAS oncogene family
chr13_+_76579681 2.12 ENSMUST00000109589.2
multiple C2 domains, transmembrane 1
chr10_+_80264942 2.12 ENSMUST00000105362.1
ENSMUST00000105361.3
DAZ associated protein 1
chr17_+_75178797 2.12 ENSMUST00000112516.1
ENSMUST00000135447.1
latent transforming growth factor beta binding protein 1
chr14_+_103513328 2.10 ENSMUST00000095576.3
sciellin
chr1_+_74125535 2.08 ENSMUST00000080167.4
ENSMUST00000127134.1
RUN and FYVE domain containing 4
chr19_+_33822908 2.08 ENSMUST00000042061.6
predicted pseudogene 5519
chr1_-_171437288 2.05 ENSMUST00000181499.1
predicted gene, 26641
chr17_-_7385305 2.04 ENSMUST00000070059.3
predicted gene 9992
chr2_-_164404606 2.04 ENSMUST00000109359.1
ENSMUST00000109358.1
ENSMUST00000103103.3
matrilin 4
chr7_-_105482197 2.03 ENSMUST00000047040.2
protein kinase C, delta binding protein
chr14_-_34588607 2.03 ENSMUST00000090040.4
LIM domain binding 3
chr2_-_45110336 2.02 ENSMUST00000028229.6
ENSMUST00000152232.1
zinc finger E-box binding homeobox 2
chr3_+_116594959 2.00 ENSMUST00000029571.8
spindle assembly 6 homolog (C. elegans)
chr14_-_70177668 1.99 ENSMUST00000022681.4
PDZ and LIM domain 2
chr9_-_32541589 1.99 ENSMUST00000016231.7
Friend leukemia integration 1
chr2_-_101797650 1.97 ENSMUST00000141814.1
ENSMUST00000171088.1
ENSMUST00000043845.7
proline rich 5 like
chr12_+_31265234 1.97 ENSMUST00000169088.1
laminin B1
chr11_+_20543307 1.95 ENSMUST00000093292.4
SERTA domain containing 2
chr3_-_92573715 1.92 ENSMUST00000053107.4
involucrin
chr2_+_174760781 1.91 ENSMUST00000140908.1
endothelin 3
chr17_+_75178911 1.90 ENSMUST00000112514.1
latent transforming growth factor beta binding protein 1
chr10_+_94550852 1.87 ENSMUST00000148910.1
ENSMUST00000117460.1
transmembrane and coiled coil domains 3
chr10_+_127290774 1.87 ENSMUST00000026475.8
ENSMUST00000139091.1
DNA-damage inducible transcript 3
chr1_+_130717320 1.86 ENSMUST00000049813.4
YOD1 OTU deubiquitinating enzyme 1 homologue (S. cerevisiae)
chr15_-_58823530 1.86 ENSMUST00000072113.5
transmembrane protein 65
chr3_+_88621436 1.85 ENSMUST00000170653.2
ENSMUST00000177303.1
rho/rac guanine nucleotide exchange factor (GEF) 2
chr12_+_31265279 1.80 ENSMUST00000002979.8
ENSMUST00000170495.1
laminin B1

Network of associatons between targets according to the STRING database.

First level regulatory network of Fos

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 21.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
4.2 25.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
3.7 18.7 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
3.0 9.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
3.0 9.1 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
2.7 13.3 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
2.6 7.8 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
2.5 9.8 GO:1903575 cornified envelope assembly(GO:1903575)
2.4 7.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
2.1 10.7 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
2.1 10.4 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
2.1 6.2 GO:0002344 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
1.8 9.2 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
1.7 3.5 GO:0035092 sperm chromatin condensation(GO:0035092)
1.7 6.8 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
1.4 4.1 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
1.3 4.0 GO:0071613 granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663)
1.3 11.8 GO:0032264 IMP salvage(GO:0032264)
1.3 6.3 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
1.3 17.6 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.2 6.2 GO:1905169 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
1.2 16.0 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
1.2 5.9 GO:2000680 regulation of rubidium ion transport(GO:2000680)
1.1 3.2 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082)
1.1 4.2 GO:0072344 rescue of stalled ribosome(GO:0072344)
1.0 7.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
1.0 20.1 GO:0032060 bleb assembly(GO:0032060)
0.9 3.8 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.9 3.8 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.9 4.4 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.9 5.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.8 3.3 GO:0042097 interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402)
0.8 4.0 GO:0044805 late nucleophagy(GO:0044805)
0.8 4.0 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.8 4.7 GO:0072675 osteoclast fusion(GO:0072675)
0.7 2.2 GO:0060364 frontal suture morphogenesis(GO:0060364)
0.7 20.6 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.7 7.8 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.6 1.9 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.6 1.7 GO:0036363 transforming growth factor beta activation(GO:0036363)
0.6 3.4 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.6 4.5 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.6 1.7 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.6 9.9 GO:0006968 cellular defense response(GO:0006968)
0.5 9.0 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.5 2.9 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.5 3.8 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.5 2.3 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.4 2.9 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.4 6.2 GO:0071361 cellular response to ethanol(GO:0071361)
0.4 4.0 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.4 11.7 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.4 1.9 GO:0014826 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826)
0.4 3.4 GO:0038203 TORC2 signaling(GO:0038203)
0.4 15.5 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.4 2.2 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.4 9.1 GO:0043486 histone exchange(GO:0043486)
0.4 16.2 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.3 20.0 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.3 2.7 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.3 2.2 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.3 4.0 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.3 3.6 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.3 2.9 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.3 1.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.3 3.0 GO:1900003 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.3 1.8 GO:0001866 NK T cell proliferation(GO:0001866)
0.3 3.6 GO:0070831 basement membrane assembly(GO:0070831)
0.3 3.1 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.2 1.0 GO:0018095 protein polyglutamylation(GO:0018095)
0.2 0.7 GO:1903438 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.2 2.5 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.2 2.7 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.2 7.7 GO:0010842 retina layer formation(GO:0010842)
0.2 0.6 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.2 1.1 GO:0051661 maintenance of centrosome location(GO:0051661)
0.2 1.0 GO:0032329 serine transport(GO:0032329)
0.2 9.2 GO:0006730 one-carbon metabolic process(GO:0006730)
0.2 1.3 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.2 0.6 GO:0060399 mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.2 2.4 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.2 4.2 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.2 0.9 GO:0030578 PML body organization(GO:0030578) positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.2 4.6 GO:0035855 megakaryocyte development(GO:0035855)
0.2 1.9 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.1 2.5 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.1 5.8 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.1 4.0 GO:0044253 positive regulation of collagen metabolic process(GO:0010714) positive regulation of collagen biosynthetic process(GO:0032967) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.1 4.3 GO:0006825 copper ion transport(GO:0006825)
0.1 1.4 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 1.0 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.5 GO:0019062 virion attachment to host cell(GO:0019062)
0.1 3.7 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.1 1.6 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.5 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 3.8 GO:0031424 keratinization(GO:0031424)
0.1 6.6 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 8.5 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.1 5.1 GO:0032720 negative regulation of tumor necrosis factor production(GO:0032720)
0.1 8.4 GO:0030239 myofibril assembly(GO:0030239)
0.1 2.0 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.1 1.0 GO:0030049 muscle filament sliding(GO:0030049)
0.1 4.2 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.1 8.5 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 1.8 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1 1.0 GO:0006020 inositol metabolic process(GO:0006020)
0.1 2.1 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 3.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.1 0.9 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373)
0.1 4.6 GO:0019933 cAMP-mediated signaling(GO:0019933)
0.1 4.0 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 0.8 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.1 2.3 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.1 0.1 GO:2000851 positive regulation of glucocorticoid secretion(GO:2000851)
0.1 2.4 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.1 0.4 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 2.0 GO:0007099 centriole replication(GO:0007099)
0.1 1.7 GO:0042481 regulation of odontogenesis(GO:0042481)
0.1 1.4 GO:0070208 protein heterotrimerization(GO:0070208)
0.1 2.4 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.1 0.7 GO:0014029 neural crest formation(GO:0014029)
0.1 0.5 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.8 GO:0050774 enteric nervous system development(GO:0048484) negative regulation of dendrite morphogenesis(GO:0050774)
0.1 1.2 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.0 2.4 GO:0021983 pituitary gland development(GO:0021983)
0.0 0.0 GO:0002572 pro-T cell differentiation(GO:0002572)
0.0 0.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 1.1 GO:0034389 lipid particle organization(GO:0034389)
0.0 1.4 GO:0019236 response to pheromone(GO:0019236)
0.0 0.2 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 4.7 GO:0098656 anion transmembrane transport(GO:0098656)
0.0 1.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.4 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 4.8 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 3.1 GO:0042089 cytokine biosynthetic process(GO:0042089)
0.0 0.6 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.5 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 3.2 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.2 GO:1901909 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.7 GO:0051281 positive regulation of release of sequestered calcium ion into cytosol(GO:0051281)
0.0 3.2 GO:0030509 BMP signaling pathway(GO:0030509)
0.0 1.0 GO:0010107 potassium ion import(GO:0010107)
0.0 0.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.3 GO:0016540 protein autoprocessing(GO:0016540)
0.0 2.6 GO:0007030 Golgi organization(GO:0007030)
0.0 0.5 GO:0033198 response to ATP(GO:0033198)
0.0 0.1 GO:0048570 notochord morphogenesis(GO:0048570)
0.0 0.9 GO:1903078 positive regulation of protein localization to plasma membrane(GO:1903078) positive regulation of protein localization to cell periphery(GO:1904377)
0.0 0.4 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.0 1.7 GO:0006338 chromatin remodeling(GO:0006338)
0.0 0.2 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.4 GO:0050798 activated T cell proliferation(GO:0050798)
0.0 1.0 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.3 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 0.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 21.1 GO:0005638 lamin filament(GO:0005638)
2.6 15.5 GO:0032437 cuticular plate(GO:0032437)
2.5 7.4 GO:0005607 laminin-2 complex(GO:0005607)
1.5 5.9 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
1.4 4.3 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
1.3 4.0 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
1.1 9.2 GO:0045098 type III intermediate filament(GO:0045098)
1.1 16.8 GO:0042581 specific granule(GO:0042581)
0.8 14.7 GO:0035686 sperm fibrous sheath(GO:0035686)
0.8 2.4 GO:1990047 spindle matrix(GO:1990047)
0.7 2.9 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.6 1.9 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.6 2.5 GO:0008623 CHRAC(GO:0008623)
0.4 18.7 GO:0015030 Cajal body(GO:0015030)
0.3 1.7 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.3 2.0 GO:0098536 deuterosome(GO:0098536)
0.3 5.7 GO:0042599 lamellar body(GO:0042599)
0.3 2.5 GO:0000138 Golgi trans cisterna(GO:0000138)
0.2 6.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 2.7 GO:0031209 SCAR complex(GO:0031209)
0.2 3.4 GO:0031932 TORC2 complex(GO:0031932)
0.2 3.8 GO:0005861 troponin complex(GO:0005861)
0.2 9.9 GO:0008180 COP9 signalosome(GO:0008180)
0.2 4.8 GO:0005922 connexon complex(GO:0005922)
0.2 5.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 0.9 GO:0005914 spot adherens junction(GO:0005914)
0.2 1.1 GO:0000235 astral microtubule(GO:0000235)
0.1 13.2 GO:0014704 intercalated disc(GO:0014704)
0.1 1.4 GO:0045298 tubulin complex(GO:0045298)
0.1 0.6 GO:0031523 Myb complex(GO:0031523)
0.1 2.8 GO:0042627 low-density lipoprotein particle(GO:0034362) chylomicron(GO:0042627)
0.1 10.4 GO:0005882 intermediate filament(GO:0005882)
0.1 2.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.5 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 21.5 GO:0008021 synaptic vesicle(GO:0008021)
0.1 1.0 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 4.8 GO:0005876 spindle microtubule(GO:0005876)
0.1 7.4 GO:0000786 nucleosome(GO:0000786)
0.1 5.7 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 3.8 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 6.8 GO:0030139 endocytic vesicle(GO:0030139)
0.1 2.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 10.8 GO:0055037 recycling endosome(GO:0055037)
0.1 12.5 GO:0005875 microtubule associated complex(GO:0005875)
0.1 3.1 GO:0002102 podosome(GO:0002102)
0.1 6.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 4.0 GO:0034707 chloride channel complex(GO:0034707)
0.1 0.7 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 2.7 GO:0016592 mediator complex(GO:0016592)
0.1 3.0 GO:0005801 cis-Golgi network(GO:0005801)
0.1 1.9 GO:0001533 cornified envelope(GO:0001533)
0.1 1.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 1.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 11.2 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.1 10.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 0.2 GO:0097444 spine apparatus(GO:0097444)
0.1 1.4 GO:0005614 interstitial matrix(GO:0005614)
0.0 2.7 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.5 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 5.1 GO:0034702 ion channel complex(GO:0034702)
0.0 1.9 GO:0016605 PML body(GO:0016605)
0.0 0.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.6 GO:0031941 filamentous actin(GO:0031941)
0.0 1.0 GO:0005844 polysome(GO:0005844)
0.0 2.4 GO:0005741 mitochondrial outer membrane(GO:0005741)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 18.7 GO:0008859 exoribonuclease II activity(GO:0008859)
3.9 15.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
3.6 25.3 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
2.6 10.6 GO:0015057 thrombin receptor activity(GO:0015057)
2.6 7.9 GO:0045353 interleukin-1, Type II receptor binding(GO:0005151) interleukin-1 Type I receptor antagonist activity(GO:0045352) interleukin-1 Type II receptor antagonist activity(GO:0045353)
2.3 11.6 GO:1990254 keratin filament binding(GO:1990254)
2.1 10.4 GO:0004668 protein-arginine deiminase activity(GO:0004668)
1.8 14.7 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.8 9.1 GO:0051373 FATZ binding(GO:0051373)
1.3 11.8 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
1.0 20.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
1.0 4.0 GO:0050436 microfibril binding(GO:0050436)
0.9 4.3 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.9 5.1 GO:0004359 glutaminase activity(GO:0004359)
0.7 3.7 GO:0030280 structural constituent of epidermis(GO:0030280)
0.7 4.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.7 7.4 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.6 5.1 GO:0045545 syndecan binding(GO:0045545)
0.6 2.4 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.6 21.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.6 1.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.5 9.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.5 3.8 GO:0042289 MHC class II protein binding(GO:0042289)
0.5 2.5 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.5 1.9 GO:0031708 endothelin B receptor binding(GO:0031708)
0.5 3.8 GO:0043208 glycosphingolipid binding(GO:0043208)
0.5 2.8 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.5 4.6 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.4 1.3 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.4 4.3 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.4 5.6 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.4 4.7 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.4 6.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.4 9.8 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.4 7.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.3 8.7 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.3 3.8 GO:0030274 LIM domain binding(GO:0030274)
0.3 8.0 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.3 2.9 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.3 11.3 GO:0001968 fibronectin binding(GO:0001968)
0.3 1.7 GO:0002135 CTP binding(GO:0002135)
0.3 8.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.3 13.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.3 5.5 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 9.1 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.3 6.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.2 1.0 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.2 5.0 GO:0019956 chemokine binding(GO:0019956)
0.2 1.9 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.2 16.0 GO:0035591 signaling adaptor activity(GO:0035591)
0.2 4.5 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.2 4.0 GO:0050811 GABA receptor binding(GO:0050811)
0.2 0.7 GO:0004947 bradykinin receptor activity(GO:0004947)
0.2 2.9 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.2 1.0 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.2 4.0 GO:0042288 MHC class I protein binding(GO:0042288)
0.2 1.6 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.2 1.9 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.2 9.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2 4.6 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.2 7.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 3.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.2 4.2 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.2 0.9 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 5.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 2.8 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 0.6 GO:0005143 growth hormone receptor binding(GO:0005131) interleukin-12 receptor binding(GO:0005143)
0.1 7.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 6.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 3.8 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 1.9 GO:0035497 cAMP response element binding(GO:0035497)
0.1 6.2 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.6 GO:0048039 ubiquinone binding(GO:0048039)
0.1 1.5 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.5 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 3.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 2.8 GO:0070412 R-SMAD binding(GO:0070412)
0.1 2.9 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 10.5 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 3.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.6 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.5 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 21.2 GO:0008017 microtubule binding(GO:0008017)
0.1 1.2 GO:0004697 protein kinase C activity(GO:0004697)
0.1 0.1 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.1 1.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 1.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.9 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 2.7 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 5.3 GO:0033613 activating transcription factor binding(GO:0033613)
0.1 2.2 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 4.0 GO:0097110 scaffold protein binding(GO:0097110)
0.1 1.4 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 1.1 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 3.6 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 7.0 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.3 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 4.4 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.0 1.0 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 1.3 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 1.3 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.6 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 4.0 GO:0022832 voltage-gated ion channel activity(GO:0005244) voltage-gated channel activity(GO:0022832)
0.0 5.8 GO:0003924 GTPase activity(GO:0003924)
0.0 1.4 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.8 GO:0005158 insulin receptor binding(GO:0005158)
0.0 1.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 8.8 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 25.3 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.7 10.6 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.6 9.9 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.6 7.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.4 28.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.3 6.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.3 11.7 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.2 1.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 3.4 ST STAT3 PATHWAY STAT3 Pathway
0.2 7.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.2 6.2 ST GA12 PATHWAY G alpha 12 Pathway
0.2 7.6 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.2 5.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.2 10.2 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.2 7.0 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.2 12.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 2.5 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 2.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 4.0 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 2.4 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 7.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 2.4 PID IL27 PATHWAY IL27-mediated signaling events
0.1 4.4 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.1 10.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 1.9 PID ENDOTHELIN PATHWAY Endothelins
0.1 3.8 PID ATM PATHWAY ATM pathway
0.1 1.3 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.1 3.1 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 4.9 PID PI3KCI PATHWAY Class I PI3K signaling events
0.1 7.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 1.4 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 2.8 SIG CHEMOTAXIS Genes related to chemotaxis
0.1 0.8 PID ALK2 PATHWAY ALK2 signaling events
0.1 3.8 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 2.8 PID P53 REGULATION PATHWAY p53 pathway
0.1 1.9 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 0.5 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.1 0.6 PID FAS PATHWAY FAS (CD95) signaling pathway
0.1 3.1 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.1 1.1 PID REELIN PATHWAY Reelin signaling pathway
0.1 3.2 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 2.2 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.4 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 4.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.3 PID IL1 PATHWAY IL1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 11.8 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.6 27.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.5 8.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.4 6.3 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.4 30.3 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.4 16.7 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.3 9.9 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.3 14.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 16.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.3 3.4 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.3 4.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.3 2.8 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 3.8 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 5.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.2 8.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2 3.8 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2 2.9 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.2 1.7 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.2 8.1 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.2 16.4 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.2 5.5 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.1 5.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 7.1 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.1 6.1 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 21.8 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 1.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 7.1 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.1 2.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 13.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 6.8 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.1 1.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 4.3 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 2.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 1.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 4.4 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 3.5 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.4 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 3.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 3.0 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 1.1 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.0 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 1.7 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 0.7 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 2.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.1 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.5 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF