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GSE58827: Dynamics of the Mouse Liver

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Results for Ets1

Z-value: 1.80

Motif logo

Transcription factors associated with Ets1

Gene Symbol Gene ID Gene Info
ENSMUSG00000032035.9 E26 avian leukemia oncogene 1, 5' domain

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Ets1mm10_v2_chr9_+_32696005_326961210.701.6e-06Click!

Activity profile of Ets1 motif

Sorted Z-values of Ets1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_71723308 15.69 ENSMUST00000125092.1
FCH domain only 1
chr11_+_87793470 14.17 ENSMUST00000020779.4
myeloperoxidase
chr11_+_87793722 13.41 ENSMUST00000143021.2
myeloperoxidase
chr2_-_28084877 12.59 ENSMUST00000028179.8
ENSMUST00000117486.1
ENSMUST00000135472.1
ficolin B
chr10_+_79886302 11.67 ENSMUST00000046091.5
elastase, neutrophil expressed
chr11_+_115887601 11.15 ENSMUST00000167507.2
myosin XVB
chr8_+_72761868 10.86 ENSMUST00000058099.8
coagulation factor II (thrombin) receptor-like 3
chr3_-_90695706 10.44 ENSMUST00000069960.5
ENSMUST00000117167.1
S100 calcium binding protein A9 (calgranulin B)
chr8_+_22974844 9.68 ENSMUST00000110688.2
ENSMUST00000121802.2
ankyrin 1, erythroid
chr17_+_25298389 9.20 ENSMUST00000037453.2
protease, serine, 34
chr7_-_127218303 8.96 ENSMUST00000106313.1
septin 1
chr7_-_127137807 8.87 ENSMUST00000049931.5
sialophorin
chr1_+_40515362 8.51 ENSMUST00000027237.5
interleukin 18 receptor accessory protein
chr7_-_127218390 8.43 ENSMUST00000142356.1
ENSMUST00000106314.1
septin 1
chr2_+_91650116 8.25 ENSMUST00000111331.2
Rho GTPase activating protein 1
chr4_+_108579445 8.09 ENSMUST00000102744.3
origin recognition complex, subunit 1
chr10_-_75940633 8.07 ENSMUST00000059658.4
predicted gene 867
chr10_+_79879614 8.07 ENSMUST00000006679.8
proteinase 3
chr2_-_26021679 7.81 ENSMUST00000036509.7
ubiquitin associated domain containing 1
chr11_-_72550255 7.72 ENSMUST00000021154.6
spinster homolog 3
chr2_-_26021532 7.64 ENSMUST00000136750.1
ubiquitin associated domain containing 1
chr2_+_91650169 7.11 ENSMUST00000090614.4
Rho GTPase activating protein 1
chr17_+_48232755 6.59 ENSMUST00000113251.3
ENSMUST00000048782.6
triggering receptor expressed on myeloid cells 1
chr6_-_40585783 6.53 ENSMUST00000177178.1
ENSMUST00000129948.2
ENSMUST00000101491.4
C-type lectin domain family 5, member a
chr19_-_4191035 6.48 ENSMUST00000045864.2
TBC1 domain family, member 10c
chr2_+_150570409 6.46 ENSMUST00000089200.2
cystatin F (leukocystatin)
chr4_-_118620763 6.32 ENSMUST00000071972.4
WD repeat domain 65
chr12_-_32208470 6.27 ENSMUST00000085469.5
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr15_+_84324716 6.21 ENSMUST00000023074.2
parvin, gamma
chr9_-_57836706 6.16 ENSMUST00000164010.1
ENSMUST00000171444.1
ENSMUST00000098686.3
AT rich interactive domain 3B (BRIGHT-like)
chr13_-_37050237 6.13 ENSMUST00000164727.1
coagulation factor XIII, A1 subunit
chr17_-_24527925 6.11 ENSMUST00000176652.1
TNF receptor-associated factor 7
chr8_-_85380964 6.03 ENSMUST00000122452.1
myosin light chain kinase 3
chr1_+_131638485 5.82 ENSMUST00000112411.1
cathepsin E
chr4_-_63403330 5.80 ENSMUST00000035724.4
AT-hook transcription factor
chr4_-_141078302 5.79 ENSMUST00000030760.8
NECAP endocytosis associated 2
chr17_-_24527830 5.76 ENSMUST00000176353.1
ENSMUST00000176237.1
TNF receptor-associated factor 7
chr17_-_33890539 5.68 ENSMUST00000173386.1
kinesin family member C1
chr2_-_156839790 5.60 ENSMUST00000134838.1
ENSMUST00000137463.1
ENSMUST00000149275.2
predicted gene 14230
chr1_+_131638306 5.51 ENSMUST00000073350.6
cathepsin E
chr3_-_89418287 5.51 ENSMUST00000029679.3
CDC28 protein kinase 1b
chr9_+_51213683 5.43 ENSMUST00000034554.7
POU domain, class 2, associating factor 1
chr4_-_152448808 5.43 ENSMUST00000159840.1
ENSMUST00000105648.2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chrX_-_7964166 5.38 ENSMUST00000128449.1
GATA binding protein 1
chr12_-_32208609 5.31 ENSMUST00000053215.7
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr6_+_87778084 5.31 ENSMUST00000032133.3
glycoprotein 9 (platelet)
chr17_-_33890584 5.30 ENSMUST00000114361.2
ENSMUST00000173492.1
kinesin family member C1
chr2_+_152847993 5.25 ENSMUST00000028969.8
TPX2, microtubule-associated protein homolog (Xenopus laevis)
chr11_+_103171081 5.25 ENSMUST00000042286.5
formin-like 1
chr17_+_46650328 5.18 ENSMUST00000043464.7
cullin 7
chr16_+_33794008 5.15 ENSMUST00000115044.1
mucin 13, epithelial transmembrane
chr16_+_33794345 5.15 ENSMUST00000023520.6
mucin 13, epithelial transmembrane
chr2_+_152847961 5.13 ENSMUST00000164120.1
ENSMUST00000178997.1
ENSMUST00000109816.1
TPX2, microtubule-associated protein homolog (Xenopus laevis)
chr7_-_126369543 5.11 ENSMUST00000032997.6
linker for activation of T cells
chr6_+_113531675 5.08 ENSMUST00000036340.5
ENSMUST00000101051.2
Fanconi anemia, complementation group D2
chr14_-_33185489 5.02 ENSMUST00000159606.1
WD repeat and FYVE domain containing 4
chr7_-_122132844 4.98 ENSMUST00000106469.1
ENSMUST00000063587.6
ENSMUST00000106468.1
ENSMUST00000130149.1
ENSMUST00000098068.3
partner and localizer of BRCA2
chr16_-_18811972 4.88 ENSMUST00000000028.7
ENSMUST00000115585.1
cell division cycle 45
chr2_-_91649785 4.87 ENSMUST00000111333.1
zinc finger protein 408
chr3_-_137981523 4.85 ENSMUST00000136613.1
ENSMUST00000029806.6
dual adaptor for phosphotyrosine and 3-phosphoinositides 1
chr7_+_127876796 4.83 ENSMUST00000131000.1
zinc finger protein 646
chr11_+_72961163 4.81 ENSMUST00000108486.1
ENSMUST00000108484.1
ENSMUST00000021142.7
ENSMUST00000108485.2
ENSMUST00000163326.1
ATPase, Ca++ transporting, ubiquitous
chr7_+_100495987 4.74 ENSMUST00000133044.1
uncoupling protein 2 (mitochondrial, proton carrier)
chr11_-_46312220 4.72 ENSMUST00000129474.1
ENSMUST00000093166.4
ENSMUST00000165599.2
cytoplasmic FMR1 interacting protein 2
chr6_+_5725639 4.71 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
dynein cytoplasmic 1 intermediate chain 1
chr17_+_32403006 4.70 ENSMUST00000065921.5
RIKEN cDNA A530088E08 gene
chr7_+_131032061 4.68 ENSMUST00000084509.3
deleted in malignant brain tumors 1
chr19_+_4154606 4.66 ENSMUST00000061086.8
protein tyrosine phosphatase, receptor type, C polypeptide-associated protein
chr3_+_103832562 4.66 ENSMUST00000062945.5
BCLl2-like 15
chr11_-_79523760 4.61 ENSMUST00000179322.1
ecotropic viral integration site 2b
chr7_+_24897381 4.59 ENSMUST00000003469.7
CD79A antigen (immunoglobulin-associated alpha)
chr14_-_19977151 4.57 ENSMUST00000055100.7
ENSMUST00000162425.1
guanine nucleotide binding protein (G protein), gamma 2
chrX_+_100625737 4.56 ENSMUST00000048962.3
kinesin family member 4
chr7_+_24370255 4.55 ENSMUST00000171904.1
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr10_+_83722865 4.46 ENSMUST00000150459.1
RIKEN cDNA 1500009L16 gene
chr9_+_56089962 4.38 ENSMUST00000059206.7
proline-serine-threonine phosphatase-interacting protein 1
chr14_-_19977040 4.36 ENSMUST00000159028.1
guanine nucleotide binding protein (G protein), gamma 2
chr2_+_22774081 4.36 ENSMUST00000014290.8
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr5_+_99979061 4.35 ENSMUST00000046721.1
RIKEN cDNA 4930524J08 gene
chr17_+_25366550 4.29 ENSMUST00000069616.7
tryptase beta 2
chr6_-_125191535 4.28 ENSMUST00000043848.4
non-SMC condensin I complex, subunit D2
chr11_+_61126747 4.26 ENSMUST00000010286.1
ENSMUST00000146033.1
ENSMUST00000139422.1
tumor necrosis factor receptor superfamily, member 13b
chr3_-_15332285 4.26 ENSMUST00000108361.1
predicted gene 9733
chr15_+_89334398 4.25 ENSMUST00000023282.2
myo-inositol oxygenase
chr1_+_171388954 4.24 ENSMUST00000056449.8
Rho GTPase activating protein 30
chr3_+_84666192 4.23 ENSMUST00000107682.1
transmembrane protein 154
chr2_-_26360873 4.21 ENSMUST00000028294.6
caspase recruitment domain family, member 9
chr3_-_20242173 4.20 ENSMUST00000001921.1
carboxypeptidase A3, mast cell
chr2_-_91649751 4.18 ENSMUST00000099714.3
zinc finger protein 408
chr9_-_20952838 4.18 ENSMUST00000004202.9
DNA methyltransferase (cytosine-5) 1
chr16_-_75909272 4.17 ENSMUST00000114239.2
SAM domain, SH3 domain and nuclear localization signals, 1
chr11_-_116076986 4.16 ENSMUST00000153408.1
unc-13 homolog D (C. elegans)
chr17_+_34590162 4.14 ENSMUST00000173772.1
G-protein signalling modulator 3 (AGS3-like, C. elegans)
chr13_-_110357136 4.12 ENSMUST00000058806.5
Grb2-binding adaptor, transmembrane
chr19_+_38097065 4.06 ENSMUST00000067098.6
free fatty acid receptor 4
chr5_+_134676490 4.05 ENSMUST00000100641.2
predicted gene 10369
chr6_+_145121727 4.05 ENSMUST00000032396.6
lymphoid-restricted membrane protein
chr1_+_152807877 4.03 ENSMUST00000027754.6
neutrophil cytosolic factor 2
chr13_+_55369732 4.01 ENSMUST00000063771.7
regulator of G-protein signaling 14
chr17_+_35241746 4.00 ENSMUST00000068056.5
ENSMUST00000174757.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr17_+_26917091 4.00 ENSMUST00000078961.4
kinesin family member C5B
chr17_+_34589799 3.98 ENSMUST00000038244.8
G-protein signalling modulator 3 (AGS3-like, C. elegans)
chr5_-_138170992 3.95 ENSMUST00000139983.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr7_-_45239041 3.91 ENSMUST00000131290.1
CD37 antigen
chr11_-_6520894 3.87 ENSMUST00000003459.3
myosin IG
chr10_-_78244602 3.85 ENSMUST00000000384.6
trafficking protein particle complex 10
chr7_+_16781341 3.80 ENSMUST00000108496.2
solute carrier family 1 (neutral amino acid transporter), member 5
chr3_+_88081997 3.76 ENSMUST00000071812.5
IQ motif containing GTPase activating protein 3
chr6_-_129917650 3.72 ENSMUST00000118060.1
killer cell lectin-like receptor, subfamily A, member 5
chr11_-_102469839 3.71 ENSMUST00000103086.3
integrin alpha 2b
chr2_-_118728345 3.70 ENSMUST00000159756.1
phospholipase C, beta 2
chr19_+_6084983 3.70 ENSMUST00000025704.2
cell division cycle associated 5
chr17_-_48409729 3.68 ENSMUST00000160319.1
ENSMUST00000159535.1
ENSMUST00000078800.6
ENSMUST00000046719.7
ENSMUST00000162460.1
nuclear transcription factor-Y alpha
chr14_+_55765956 3.67 ENSMUST00000057569.3
leukotriene B4 receptor 1
chr11_-_17008647 3.67 ENSMUST00000102881.3
pleckstrin
chr5_-_123879992 3.64 ENSMUST00000164267.1
G protein-coupled receptor 81
chr9_+_56418624 3.63 ENSMUST00000034879.3
high mobility group 20A
chr17_+_35241838 3.61 ENSMUST00000173731.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr2_-_32083783 3.61 ENSMUST00000056406.6
family with sequence similarity 78, member A
chr11_+_104550663 3.60 ENSMUST00000018800.2
myosin, light polypeptide 4
chr15_-_100669496 3.56 ENSMUST00000182814.1
ENSMUST00000182068.1
bridging integrator 2
chr14_-_33185066 3.54 ENSMUST00000061753.8
ENSMUST00000130509.2
WD repeat and FYVE domain containing 4
chr7_+_142442330 3.50 ENSMUST00000149529.1
troponin I, skeletal, fast 2
chr2_+_163602331 3.49 ENSMUST00000152135.1
tocopherol (alpha) transfer protein-like
chr15_-_100669535 3.46 ENSMUST00000183211.1
bridging integrator 2
chr7_-_45239108 3.42 ENSMUST00000033063.6
CD37 antigen
chr11_-_98400453 3.40 ENSMUST00000090827.5
post-GPI attachment to proteins 3
chr19_-_20390944 3.35 ENSMUST00000025561.7
annexin A1
chr18_+_50030977 3.34 ENSMUST00000145726.1
ENSMUST00000128377.1
tumor necrosis factor, alpha-induced protein 8
chr12_-_78906929 3.32 ENSMUST00000021544.7
pleckstrin 2
chr11_-_76509419 3.32 ENSMUST00000094012.4
active BCR-related gene
chr3_-_127409014 3.31 ENSMUST00000182008.1
ENSMUST00000182711.1
ENSMUST00000182547.1
ankyrin 2, brain
chr16_-_19983005 3.30 ENSMUST00000058839.8
kelch-like 6
chr5_-_65091584 3.29 ENSMUST00000043352.4
transmembrane protein 156
chr7_+_62348277 3.27 ENSMUST00000038775.4
necdin
chr2_-_164356507 3.27 ENSMUST00000109367.3
secretory leukocyte peptidase inhibitor
chr3_-_14778452 3.26 ENSMUST00000094365.4
carbonic anhydrase 1
chr11_-_98400393 3.26 ENSMUST00000128897.1
post-GPI attachment to proteins 3
chr9_+_27030159 3.22 ENSMUST00000073127.7
ENSMUST00000086198.4
non-SMC condensin II complex, subunit D3
chr3_+_10012548 3.21 ENSMUST00000029046.8
fatty acid binding protein 5, epidermal
chr4_-_129573637 3.20 ENSMUST00000102596.1
lymphocyte protein tyrosine kinase
chr12_-_115964196 3.20 ENSMUST00000103550.2
immunoglobulin heavy variable 1-83
chr14_-_19977249 3.19 ENSMUST00000160013.1
guanine nucleotide binding protein (G protein), gamma 2
chr4_+_135152496 3.17 ENSMUST00000119564.1
runt related transcription factor 3
chr1_-_38664947 3.15 ENSMUST00000039827.7
ENSMUST00000027250.7
AF4/FMR2 family, member 3
chr15_-_66812593 3.13 ENSMUST00000100572.3
src-like adaptor
chr17_+_34605855 3.13 ENSMUST00000037489.8
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chrX_-_8090442 3.12 ENSMUST00000033505.6
Wiskott-Aldrich syndrome homolog (human)
chr3_+_68869563 3.11 ENSMUST00000054551.2
RIKEN cDNA 1110032F04 gene
chr8_+_94977101 3.11 ENSMUST00000179619.1
G protein-coupled receptor 56
chr1_+_135133272 3.11 ENSMUST00000167080.1
protein tyrosine phosphatase, non-receptor type 7
chr17_+_35135463 3.10 ENSMUST00000173535.1
ENSMUST00000173952.1
BCL2-associated athanogene 6
chr2_-_73486456 3.10 ENSMUST00000141264.1
WAS/WASL interacting protein family, member 1
chr2_+_156840077 3.09 ENSMUST00000081335.6
ENSMUST00000073352.3
TGFB-induced factor homeobox 2
chr16_-_92826004 3.09 ENSMUST00000023673.7
runt related transcription factor 1
chr17_+_33555719 3.05 ENSMUST00000087605.5
ENSMUST00000174695.1
myosin IF
chr1_+_107511489 3.03 ENSMUST00000064916.2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr1_+_107511416 3.01 ENSMUST00000009356.4
serine (or cysteine) peptidase inhibitor, clade B, member 2
chrX_-_74428871 3.00 ENSMUST00000143521.1
glucose-6-phosphate dehydrogenase X-linked
chr5_-_137072254 3.00 ENSMUST00000077523.3
ENSMUST00000041388.4
serine (or cysteine) peptidase inhibitor, clade E, member 1
chr4_-_122885965 2.99 ENSMUST00000128485.1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr14_-_31494992 2.99 ENSMUST00000055303.3
methyltransferase like 6
chr2_-_165400398 2.98 ENSMUST00000029213.4
osteoclast stimulatory transmembrane protein
chr3_-_27896360 2.97 ENSMUST00000058077.3
transmembrane protein 212
chr11_+_43528759 2.97 ENSMUST00000050574.6
cyclin J-like
chrX_-_150813637 2.97 ENSMUST00000112700.1
melanoma antigen, family D, 2
chr14_-_70175397 2.95 ENSMUST00000143393.1
PDZ and LIM domain 2
chr3_+_28781305 2.93 ENSMUST00000060500.7
eukaryotic translation initiation factor 5A2
chr3_-_127408986 2.89 ENSMUST00000182588.1
ENSMUST00000182959.1
ENSMUST00000182452.1
ankyrin 2, brain
chr8_-_94037007 2.88 ENSMUST00000034204.9
nudix (nucleoside diphosphate linked moiety X)-type motif 21
chr3_-_129831374 2.88 ENSMUST00000029643.8
GAR1 ribonucleoprotein homolog (yeast)
chr7_-_25615874 2.87 ENSMUST00000098663.1
predicted gene 7092
chr18_-_24603464 2.87 ENSMUST00000154205.1
solute carrier family 39 (metal ion transporter), member 6
chr8_+_88289028 2.86 ENSMUST00000171456.1
adenylate cyclase 7
chr2_-_172370506 2.85 ENSMUST00000109139.1
ENSMUST00000028997.7
ENSMUST00000109140.3
aurora kinase A
chr11_-_11462408 2.84 ENSMUST00000020413.3
zona pellucida binding protein
chr9_+_122923050 2.83 ENSMUST00000051667.7
ENSMUST00000148851.1
zinc finger protein 105
chr1_-_133690100 2.83 ENSMUST00000169295.1
lymphocyte transmembrane adaptor 1
chr18_-_24603791 2.82 ENSMUST00000070726.3
solute carrier family 39 (metal ion transporter), member 6
chr11_+_69914179 2.79 ENSMUST00000057884.5
G protein pathway suppressor 2
chr6_+_125552948 2.79 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Von Willebrand factor homolog
chr19_+_53529100 2.79 ENSMUST00000038287.6
dual specificity phosphatase 5
chr2_+_118814195 2.78 ENSMUST00000110842.1
kinetochore-localized astrin/SPAG5 binding
chr17_+_27057288 2.77 ENSMUST00000049308.8
inositol 1,4,5-triphosphate receptor 3
chr4_-_129558387 2.76 ENSMUST00000067240.4
lymphocyte protein tyrosine kinase
chr15_+_78244781 2.75 ENSMUST00000096357.5
ENSMUST00000133618.1
neutrophil cytosolic factor 4
chr5_-_116024475 2.75 ENSMUST00000111999.1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr7_-_44748306 2.74 ENSMUST00000118162.1
ENSMUST00000140599.2
ENSMUST00000120798.1
zinc finger protein 473
chr5_-_138171248 2.70 ENSMUST00000153867.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr13_-_19619820 2.70 ENSMUST00000002885.6
ependymin related protein 1 (zebrafish)
chr11_+_69965396 2.69 ENSMUST00000018713.6
claudin 7
chr15_+_57985873 2.67 ENSMUST00000050374.2
family with sequence similarity 83, member A
chr1_+_135132693 2.66 ENSMUST00000049449.4
protein tyrosine phosphatase, non-receptor type 7
chr2_+_118814237 2.66 ENSMUST00000028803.7
ENSMUST00000126045.1
kinetochore-localized astrin/SPAG5 binding
chr4_-_129558355 2.65 ENSMUST00000167288.1
ENSMUST00000134336.1
lymphocyte protein tyrosine kinase
chr6_+_65778988 2.64 ENSMUST00000031976.7
ENSMUST00000081219.7
ENSMUST00000031973.6
ENSMUST00000172638.1
PR domain containing 5
chr5_-_134614953 2.63 ENSMUST00000036362.6
ENSMUST00000077636.4
linker for activation of T cells family, member 2
chr7_-_100856289 2.62 ENSMUST00000139604.1
RELT tumor necrosis factor receptor
chr3_-_109027600 2.61 ENSMUST00000171143.1
family with sequence similarity 102, member B
chr14_+_20674311 2.61 ENSMUST00000048657.8
Sec24 related gene family, member C (S. cerevisiae)

Network of associatons between targets according to the STRING database.

First level regulatory network of Ets1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
9.2 27.6 GO:0002148 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
5.1 20.2 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
3.9 11.7 GO:0070947 neutrophil mediated killing of fungus(GO:0070947)
3.7 11.0 GO:0072382 minus-end-directed vesicle transport along microtubule(GO:0072382)
3.5 10.4 GO:0070488 neutrophil aggregation(GO:0070488)
3.1 12.6 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
3.0 8.9 GO:0001807 regulation of type IV hypersensitivity(GO:0001807) negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865) negative regulation of hypersensitivity(GO:0002884)
2.6 15.4 GO:0032439 endosome localization(GO:0032439) negative regulation of vacuolar transport(GO:1903336)
1.9 9.4 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
1.8 5.4 GO:0030221 basophil differentiation(GO:0030221)
1.7 11.6 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
1.6 4.9 GO:0071163 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) DNA replication preinitiation complex assembly(GO:0071163) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
1.6 8.1 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
1.6 1.6 GO:0032741 positive regulation of interleukin-18 production(GO:0032741)
1.5 4.5 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
1.4 4.2 GO:0036292 DNA rewinding(GO:0036292)
1.3 4.0 GO:0045763 regulation of arginine metabolic process(GO:0000821) negative regulation of nitric oxide mediated signal transduction(GO:0010751) negative regulation of cellular amino acid metabolic process(GO:0045763)
1.3 1.3 GO:2000412 positive regulation of thymocyte migration(GO:2000412)
1.2 7.3 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
1.2 10.9 GO:0045048 protein insertion into ER membrane(GO:0045048)
1.2 6.0 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
1.2 3.5 GO:0071846 actin filament debranching(GO:0071846)
1.2 10.5 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
1.1 3.3 GO:1904732 regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
1.1 7.5 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
1.1 5.3 GO:0002457 T cell antigen processing and presentation(GO:0002457)
1.1 3.2 GO:0002946 tRNA C5-cytosine methylation(GO:0002946)
1.0 7.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
1.0 4.2 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
1.0 14.5 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
1.0 3.1 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
1.0 6.0 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
1.0 3.0 GO:1904879 pentose-phosphate shunt, oxidative branch(GO:0009051) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
1.0 3.0 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
1.0 3.9 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
1.0 9.7 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.9 3.8 GO:0015825 L-serine transport(GO:0015825)
0.9 7.5 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.9 1.8 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.9 11.9 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.9 7.3 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.9 8.9 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.9 12.4 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.9 2.6 GO:0030043 actin filament fragmentation(GO:0030043)
0.9 2.6 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
0.8 13.3 GO:0045588 positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
0.8 3.2 GO:0010286 heat acclimation(GO:0010286)
0.8 2.4 GO:0009826 unidimensional cell growth(GO:0009826)
0.8 8.4 GO:0002283 neutrophil activation involved in immune response(GO:0002283)
0.8 9.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.8 5.3 GO:0072674 multinuclear osteoclast differentiation(GO:0072674)
0.8 2.3 GO:0021570 rhombomere 4 development(GO:0021570)
0.7 2.9 GO:0030576 Cajal body organization(GO:0030576)
0.7 2.2 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.7 2.8 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.7 2.8 GO:0045659 negative regulation of neutrophil differentiation(GO:0045659)
0.7 4.8 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.7 2.8 GO:0046898 response to cycloheximide(GO:0046898)
0.7 2.0 GO:1903972 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.7 2.0 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.7 4.0 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.7 3.3 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.7 9.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.7 2.0 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.7 0.7 GO:0032831 positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
0.6 2.6 GO:0006014 D-ribose metabolic process(GO:0006014)
0.6 3.2 GO:0042117 monocyte activation(GO:0042117)
0.6 17.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.6 1.8 GO:0032470 positive regulation of endoplasmic reticulum calcium ion concentration(GO:0032470) maintenance of mitochondrion location(GO:0051659) relaxation of skeletal muscle(GO:0090076)
0.6 1.8 GO:0010716 regulation of collagen catabolic process(GO:0010710) negative regulation of extracellular matrix disassembly(GO:0010716)
0.6 5.4 GO:0002432 granuloma formation(GO:0002432)
0.6 4.7 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.6 5.9 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.6 5.9 GO:0051014 actin filament severing(GO:0051014)
0.6 2.9 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.6 1.7 GO:0032701 negative regulation of granulocyte macrophage colony-stimulating factor production(GO:0032685) negative regulation of interleukin-18 production(GO:0032701)
0.6 2.8 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.6 6.1 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.6 2.2 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.6 2.2 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.5 1.6 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.5 1.1 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.5 2.6 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.5 4.1 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.5 9.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.5 4.6 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.5 2.0 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.5 1.5 GO:1904980 regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
0.5 2.5 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.5 1.5 GO:0001698 gastrin-induced gastric acid secretion(GO:0001698)
0.5 2.0 GO:0032053 ciliary basal body organization(GO:0032053)
0.5 2.0 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.5 1.5 GO:0035709 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.5 1.4 GO:0002355 detection of tumor cell(GO:0002355)
0.5 5.2 GO:0035878 nail development(GO:0035878)
0.5 6.1 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.5 7.9 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.5 2.3 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.5 1.8 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.5 2.8 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.5 2.3 GO:0009597 detection of virus(GO:0009597)
0.5 1.8 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.4 8.9 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.4 1.3 GO:0048611 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.4 7.9 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.4 0.4 GO:0018307 enzyme active site formation(GO:0018307)
0.4 1.3 GO:2000434 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.4 5.9 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.4 0.8 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.4 1.2 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.4 1.2 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.4 1.2 GO:0006742 NADP catabolic process(GO:0006742)
0.4 1.6 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.4 4.3 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.4 2.4 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.4 1.2 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.4 3.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.4 1.6 GO:0061152 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.4 1.2 GO:1901355 response to rapamycin(GO:1901355)
0.4 4.2 GO:0045408 regulation of interleukin-6 biosynthetic process(GO:0045408)
0.4 5.7 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.4 3.4 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.4 1.1 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.4 0.7 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.4 2.6 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.4 4.8 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.4 2.2 GO:0032532 regulation of microvillus length(GO:0032532)
0.4 2.8 GO:0070294 renal sodium ion absorption(GO:0070294)
0.4 2.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.4 1.8 GO:0044849 estrous cycle(GO:0044849)
0.3 3.8 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.3 0.7 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.3 0.7 GO:2000043 regulation of cardiac cell fate specification(GO:2000043)
0.3 8.3 GO:0032460 negative regulation of protein oligomerization(GO:0032460)
0.3 0.7 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.3 6.2 GO:0050913 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) sensory perception of bitter taste(GO:0050913)
0.3 13.6 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.3 4.2 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.3 5.1 GO:0006968 cellular defense response(GO:0006968)
0.3 1.6 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.3 5.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.3 1.6 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.3 1.2 GO:1903027 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.3 0.9 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.3 1.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.3 0.9 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.3 1.5 GO:0023041 neuronal signal transduction(GO:0023041)
0.3 0.9 GO:0036090 cleavage furrow ingression(GO:0036090)
0.3 0.9 GO:0048478 replication fork protection(GO:0048478)
0.3 4.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.3 0.9 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.3 0.9 GO:0006597 spermine biosynthetic process(GO:0006597)
0.3 4.4 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.3 0.6 GO:0072708 response to sorbitol(GO:0072708)
0.3 0.9 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.3 0.6 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.3 1.4 GO:0021993 initiation of neural tube closure(GO:0021993)
0.3 1.1 GO:1904796 regulation of core promoter binding(GO:1904796)
0.3 15.5 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.3 1.4 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.3 0.8 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
0.3 3.8 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.3 1.1 GO:0031296 B cell costimulation(GO:0031296)
0.3 4.8 GO:0001675 acrosome assembly(GO:0001675)
0.3 0.8 GO:0070476 rRNA (guanine-N7)-methylation(GO:0070476)
0.3 0.8 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.3 0.5 GO:0002309 T cell proliferation involved in immune response(GO:0002309)
0.3 0.8 GO:0032962 regulation of inositol trisphosphate biosynthetic process(GO:0032960) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.3 3.2 GO:0006020 inositol metabolic process(GO:0006020)
0.3 0.5 GO:2000554 T-helper 1 cell cytokine production(GO:0035744) regulation of T-helper 1 cell cytokine production(GO:2000554) positive regulation of T-helper 1 cell cytokine production(GO:2000556)
0.3 1.0 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.3 1.3 GO:1902339 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.3 1.5 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.3 5.1 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.3 2.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.3 1.0 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.2 1.7 GO:0016266 O-glycan processing(GO:0016266)
0.2 1.5 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.2 1.0 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.2 0.7 GO:1903660 transforming growth factor beta activation(GO:0036363) regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.2 2.4 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.2 6.5 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.2 0.9 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.2 1.4 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.2 1.4 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.2 1.8 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.2 1.4 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.2 1.1 GO:1901228 positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.2 3.4 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.2 0.9 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.2 9.2 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.2 0.4 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.2 2.9 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.2 0.7 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.2 1.3 GO:0032079 positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.2 1.7 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.2 1.1 GO:0001840 neural plate development(GO:0001840)
0.2 0.9 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.2 0.9 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.2 0.4 GO:1990859 cellular response to endothelin(GO:1990859)
0.2 1.7 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.2 2.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.2 0.4 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.2 1.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.2 7.5 GO:1903146 regulation of mitophagy(GO:1903146)
0.2 1.0 GO:0032596 protein transport into membrane raft(GO:0032596)
0.2 1.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2 1.6 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.2 1.0 GO:0007256 activation of JNKK activity(GO:0007256)
0.2 2.2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.2 0.6 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.2 2.0 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.2 1.3 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.2 2.7 GO:0043485 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.2 1.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.2 1.1 GO:0051031 tRNA transport(GO:0051031)
0.2 1.0 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.2 3.2 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.2 2.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.2 2.4 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.2 1.9 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.2 3.9 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.2 0.7 GO:0072737 response to diamide(GO:0072737) cellular response to diamide(GO:0072738) cellular response to sodium arsenite(GO:1903936)
0.2 1.3 GO:0006621 protein retention in ER lumen(GO:0006621)
0.2 5.7 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.2 1.1 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.2 0.2 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.2 1.1 GO:1902969 mitotic DNA replication(GO:1902969)
0.2 7.0 GO:0045761 regulation of adenylate cyclase activity(GO:0045761)
0.2 0.9 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.2 1.4 GO:0070970 interleukin-2 secretion(GO:0070970)
0.2 0.2 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.2 0.5 GO:0002587 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002587)
0.2 0.7 GO:0061146 midgut development(GO:0007494) Peyer's patch morphogenesis(GO:0061146)
0.2 0.5 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.2 7.9 GO:0006284 base-excision repair(GO:0006284)
0.2 2.2 GO:0070995 NADPH oxidation(GO:0070995)
0.2 5.5 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.2 1.4 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.2 1.0 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
0.2 1.3 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.2 4.9 GO:0019731 antibacterial humoral response(GO:0019731)
0.2 0.8 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.2 1.8 GO:0001771 immunological synapse formation(GO:0001771)
0.2 0.6 GO:0001927 exocyst assembly(GO:0001927)
0.2 1.1 GO:0071280 cellular response to copper ion(GO:0071280)
0.2 0.8 GO:1902167 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
0.2 3.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 3.3 GO:0007413 axonal fasciculation(GO:0007413)
0.2 1.4 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2 3.4 GO:0099612 protein localization to axon(GO:0099612)
0.2 0.8 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.2 6.5 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.2 1.8 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 2.0 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.1 7.8 GO:0045576 mast cell activation(GO:0045576)
0.1 2.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.6 GO:0060279 positive regulation of ovulation(GO:0060279)
0.1 1.0 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 0.4 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.1 1.5 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.7 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 2.6 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.9 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.1 3.3 GO:0045954 positive regulation of natural killer cell mediated immunity(GO:0002717) positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.1 0.9 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.1 1.7 GO:0098792 xenophagy(GO:0098792)
0.1 0.3 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.1 1.0 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.1 0.4 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.1 0.3 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.1 2.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.1 0.6 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 4.0 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.1 1.4 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.1 0.9 GO:0070475 rRNA base methylation(GO:0070475)
0.1 0.5 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.3 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.1 0.4 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 1.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.1 0.5 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 0.4 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.1 3.1 GO:0000281 mitotic cytokinesis(GO:0000281)
0.1 0.5 GO:0021764 amygdala development(GO:0021764)
0.1 0.8 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.1 1.0 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.1 0.4 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.9 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 0.2 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.1 0.4 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
0.1 0.8 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.1 0.5 GO:0070889 platelet alpha granule organization(GO:0070889)
0.1 0.5 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 0.5 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.1 2.8 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.1 0.9 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 0.5 GO:0032218 riboflavin transport(GO:0032218)
0.1 0.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.4 GO:0031509 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.1 0.1 GO:0032202 negative regulation of protein ADP-ribosylation(GO:0010836) telomere assembly(GO:0032202)
0.1 2.4 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.1 0.5 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 0.4 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 3.3 GO:0007616 long-term memory(GO:0007616)
0.1 1.2 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.1 4.4 GO:0006611 protein export from nucleus(GO:0006611)
0.1 1.8 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.1 0.5 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.1 0.2 GO:0002339 B cell selection(GO:0002339) B cell negative selection(GO:0002352)
0.1 2.3 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 0.5 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.1 GO:0061010 gall bladder development(GO:0061010)
0.1 3.3 GO:0050710 negative regulation of cytokine secretion(GO:0050710)
0.1 1.4 GO:0015747 urate transport(GO:0015747)
0.1 0.5 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.1 4.7 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 1.9 GO:0021895 cerebral cortex neuron differentiation(GO:0021895)
0.1 1.2 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 8.6 GO:2000117 negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.1 0.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 4.1 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.1 3.1 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.1 2.2 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.1 0.7 GO:0071493 cellular response to UV-B(GO:0071493)
0.1 6.5 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 0.1 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.1 1.1 GO:0032785 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.1 0.7 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.7 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.8 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.1 0.3 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 1.1 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 2.5 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.8 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.5 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.1 0.2 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.1 2.6 GO:0051567 histone H3-K9 methylation(GO:0051567)
0.1 0.9 GO:1904871 protein localization to nuclear body(GO:1903405) positive regulation of establishment of protein localization to telomere(GO:1904851) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.1 1.4 GO:0031297 replication fork processing(GO:0031297)
0.1 0.4 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.1 2.7 GO:0043631 RNA polyadenylation(GO:0043631)
0.1 0.4 GO:1990928 response to amino acid starvation(GO:1990928)
0.1 2.9 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.1 2.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.1 0.3 GO:0007000 nucleolus organization(GO:0007000)
0.1 0.5 GO:1905146 lysosomal protein catabolic process(GO:1905146)
0.1 3.5 GO:0070527 platelet aggregation(GO:0070527)
0.1 1.2 GO:0042269 regulation of natural killer cell mediated cytotoxicity(GO:0042269)
0.1 0.1 GO:0002863 positive regulation of inflammatory response to antigenic stimulus(GO:0002863)
0.1 2.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 0.3 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.1 0.3 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 2.5 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 1.3 GO:0042993 positive regulation of transcription factor import into nucleus(GO:0042993)
0.1 0.3 GO:0006273 lagging strand elongation(GO:0006273)
0.1 0.3 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.1 1.3 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.1 1.9 GO:0060004 reflex(GO:0060004)
0.1 0.8 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.7 GO:0009452 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.1 0.2 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 1.5 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.1 0.2 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118)
0.1 0.5 GO:1900120 regulation of receptor binding(GO:1900120)
0.1 2.1 GO:0032611 interleukin-1 beta production(GO:0032611)
0.1 0.2 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.1 0.5 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 0.4 GO:0006265 DNA topological change(GO:0006265)
0.1 0.8 GO:0006751 glutathione catabolic process(GO:0006751)
0.1 0.1 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.1 1.1 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.1 0.2 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.1 0.3 GO:0046628 positive regulation of insulin receptor signaling pathway(GO:0046628)
0.1 1.8 GO:0048266 behavioral response to pain(GO:0048266)
0.1 0.2 GO:0006713 glucocorticoid catabolic process(GO:0006713)
0.1 0.2 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.1 0.4 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725) positive regulation of glycogen metabolic process(GO:0070875)
0.1 0.7 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 1.8 GO:0051973 positive regulation of telomerase activity(GO:0051973)
0.0 0.1 GO:0046881 positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0 0.7 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 1.1 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.4 GO:0048680 positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0 1.4 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.4 GO:0060065 uterus development(GO:0060065)
0.0 0.4 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0 0.4 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.0 0.4 GO:0031268 pseudopodium organization(GO:0031268)
0.0 1.2 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.8 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.2 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.5 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.2 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
0.0 0.3 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 1.8 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 1.1 GO:0050819 negative regulation of coagulation(GO:0050819)
0.0 0.3 GO:0015074 DNA integration(GO:0015074)
0.0 0.3 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 0.6 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0 3.4 GO:0007338 single fertilization(GO:0007338)
0.0 0.3 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.9 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.9 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.3 GO:0071362 interleukin-21 production(GO:0032625) cellular response to ether(GO:0071362) interleukin-21 secretion(GO:0072619) response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 0.3 GO:0001553 luteinization(GO:0001553)
0.0 0.3 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.7 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.1 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.0 1.3 GO:0006414 translational elongation(GO:0006414)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.0 GO:0046619 optic placode formation(GO:0001743) optic placode formation involved in camera-type eye formation(GO:0046619)
0.0 0.6 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.8 GO:0006541 glutamine metabolic process(GO:0006541)
0.0 2.0 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.4 GO:0098534 centriole replication(GO:0007099) centriole assembly(GO:0098534)
0.0 0.7 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.0 GO:0040010 positive regulation of growth rate(GO:0040010)
0.0 2.0 GO:0001889 liver development(GO:0001889)
0.0 0.4 GO:0038065 collagen-activated signaling pathway(GO:0038065)
0.0 0.1 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.0 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 1.0 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.0 0.6 GO:0007091 metaphase/anaphase transition of mitotic cell cycle(GO:0007091)
0.0 1.2 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.9 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.1 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.6 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 1.1 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.6 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.2 GO:0030225 macrophage differentiation(GO:0030225)
0.0 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.2 GO:0008105 asymmetric protein localization(GO:0008105)
0.0 0.1 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.0 0.6 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.1 GO:1903020 positive regulation of glycoprotein metabolic process(GO:1903020)
0.0 0.5 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 1.0 GO:0043473 pigmentation(GO:0043473)
0.0 0.6 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 1.8 GO:0000398 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 0.1 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.1 GO:0031507 heterochromatin assembly(GO:0031507)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 13.7 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
2.7 16.2 GO:0097443 sorting endosome(GO:0097443)
2.5 7.5 GO:0000799 nuclear condensin complex(GO:0000799)
2.0 6.1 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
1.6 4.9 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
1.6 24.8 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
1.5 17.9 GO:0072687 meiotic spindle(GO:0072687)
1.3 9.4 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
1.2 6.2 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
1.2 15.9 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
1.2 8.2 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
1.1 13.0 GO:0005687 U4 snRNP(GO:0005687)
1.1 5.3 GO:1990769 proximal neuron projection(GO:1990769)
1.0 8.3 GO:0005818 aster(GO:0005818)
0.9 3.6 GO:0008623 CHRAC(GO:0008623)
0.9 9.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.9 5.2 GO:1990393 3M complex(GO:1990393)
0.8 9.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.8 2.5 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.8 10.7 GO:0042555 MCM complex(GO:0042555)
0.8 2.3 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.7 2.2 GO:0005607 laminin-2 complex(GO:0005607)
0.7 2.9 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
0.7 4.7 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.7 2.0 GO:0071001 U4/U6 snRNP(GO:0071001)
0.6 5.8 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.6 4.4 GO:0019815 B cell receptor complex(GO:0019815)
0.6 3.7 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.6 3.0 GO:0042583 chromaffin granule(GO:0042583)
0.6 7.0 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.6 10.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.5 4.4 GO:0005826 actomyosin contractile ring(GO:0005826)
0.5 1.6 GO:0036019 endolysosome(GO:0036019)
0.5 3.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.5 2.0 GO:0008537 proteasome activator complex(GO:0008537)
0.5 1.0 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.5 23.5 GO:0031430 M band(GO:0031430)
0.5 2.9 GO:0001651 dense fibrillar component(GO:0001651)
0.5 6.5 GO:0031527 filopodium membrane(GO:0031527)
0.5 5.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.5 1.8 GO:0071438 invadopodium membrane(GO:0071438)
0.4 22.3 GO:0001772 immunological synapse(GO:0001772)
0.4 3.7 GO:0008278 cohesin complex(GO:0008278)
0.4 11.9 GO:0001891 phagocytic cup(GO:0001891)
0.4 1.6 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.4 3.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.4 1.2 GO:0032783 ELL-EAF complex(GO:0032783)
0.4 1.5 GO:1902737 viral replication complex(GO:0019034) dendritic filopodium(GO:1902737)
0.4 5.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.4 2.9 GO:0042382 paraspeckles(GO:0042382)
0.3 19.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.3 10.3 GO:0035371 microtubule plus-end(GO:0035371)
0.3 1.9 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.3 1.8 GO:0031673 H zone(GO:0031673)
0.3 1.2 GO:0031298 replication fork protection complex(GO:0031298)
0.3 0.9 GO:0030905 retromer, tubulation complex(GO:0030905)
0.3 5.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.3 1.7 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.3 22.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.3 0.8 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.3 1.3 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.3 1.6 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.3 2.3 GO:0016600 flotillin complex(GO:0016600)
0.3 1.0 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.3 13.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 2.2 GO:0071141 SMAD protein complex(GO:0071141)
0.2 1.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.2 1.9 GO:0097208 alveolar lamellar body(GO:0097208)
0.2 3.6 GO:0031672 A band(GO:0031672)
0.2 1.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 3.1 GO:0000974 Prp19 complex(GO:0000974)
0.2 2.1 GO:0061574 ASAP complex(GO:0061574)
0.2 11.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.2 0.7 GO:0097543 ciliary inversin compartment(GO:0097543)
0.2 3.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 3.7 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.2 12.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 1.1 GO:0034709 methylosome(GO:0034709)
0.2 8.7 GO:0015030 Cajal body(GO:0015030)
0.2 24.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 0.4 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.2 1.4 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.2 0.4 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.2 5.1 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 1.7 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 3.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.2 0.8 GO:0005688 U6 snRNP(GO:0005688)
0.2 1.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2 7.0 GO:0002102 podosome(GO:0002102)
0.2 0.7 GO:0005682 U5 snRNP(GO:0005682)
0.2 0.9 GO:1990745 EARP complex(GO:1990745)
0.2 12.9 GO:0030118 clathrin coat(GO:0030118)
0.2 1.6 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.2 2.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 1.4 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.2 0.6 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 0.7 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 2.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 4.2 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 1.4 GO:0001739 sex chromatin(GO:0001739)
0.1 2.5 GO:0005861 troponin complex(GO:0005861)
0.1 1.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.1 1.6 GO:0005686 U2 snRNP(GO:0005686)
0.1 7.4 GO:0005871 kinesin complex(GO:0005871)
0.1 1.9 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.4 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 3.2 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 1.1 GO:0030314 junctional membrane complex(GO:0030314)
0.1 4.1 GO:0008305 integrin complex(GO:0008305)
0.1 3.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 2.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 0.5 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 3.5 GO:0097228 sperm principal piece(GO:0097228)
0.1 1.6 GO:0017119 Golgi transport complex(GO:0017119)
0.1 9.3 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 0.9 GO:0070938 contractile ring(GO:0070938)
0.1 1.4 GO:0031932 TORC2 complex(GO:0031932)
0.1 1.6 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 1.6 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.1 1.9 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.3 GO:0005940 septin ring(GO:0005940)
0.1 0.7 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 1.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 0.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.8 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 1.2 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.1 0.7 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.2 GO:0044194 cytolytic granule(GO:0044194)
0.1 0.4 GO:0061689 tricellular tight junction(GO:0061689)
0.1 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 1.4 GO:0000421 autophagosome membrane(GO:0000421)
0.1 1.8 GO:0043196 varicosity(GO:0043196)
0.1 1.2 GO:0036038 MKS complex(GO:0036038)
0.1 0.7 GO:0005767 secondary lysosome(GO:0005767) autolysosome(GO:0044754)
0.1 1.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 1.6 GO:0042588 zymogen granule(GO:0042588)
0.1 0.8 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.1 5.0 GO:0016459 myosin complex(GO:0016459)
0.1 0.5 GO:0043219 lateral loop(GO:0043219)
0.1 1.1 GO:0045120 pronucleus(GO:0045120)
0.1 0.4 GO:0001740 Barr body(GO:0001740)
0.1 1.1 GO:0051233 spindle midzone(GO:0051233)
0.1 0.5 GO:0071011 precatalytic spliceosome(GO:0071011)
0.1 0.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 6.5 GO:0030139 endocytic vesicle(GO:0030139)
0.1 0.6 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 0.7 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 2.8 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.2 GO:0097422 tubular endosome(GO:0097422)
0.0 25.2 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.2 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.3 GO:0000125 PCAF complex(GO:0000125)
0.0 4.0 GO:0005814 centriole(GO:0005814)
0.0 0.7 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 4.6 GO:0005884 actin filament(GO:0005884)
0.0 1.5 GO:0030686 90S preribosome(GO:0030686)
0.0 1.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 1.1 GO:0030673 axolemma(GO:0030673)
0.0 0.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.5 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 3.4 GO:0016605 PML body(GO:0016605)
0.0 0.4 GO:0031143 pseudopodium(GO:0031143)
0.0 1.4 GO:0005657 replication fork(GO:0005657)
0.0 0.8 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 4.8 GO:0001650 fibrillar center(GO:0001650)
0.0 0.9 GO:0043194 axon initial segment(GO:0043194)
0.0 5.5 GO:0001726 ruffle(GO:0001726)
0.0 0.7 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 4.6 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 0.4 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.0 0.1 GO:0090543 Flemming body(GO:0090543)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.7 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.8 GO:0000922 spindle pole(GO:0000922)
0.0 0.9 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.3 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 1.0 GO:0030315 T-tubule(GO:0030315)
0.0 0.5 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 1.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.6 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.4 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0070187 telosome(GO:0070187)
0.0 2.4 GO:0005903 brush border(GO:0005903)
0.0 0.9 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 4.0 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.3 GO:0044452 nucleolar part(GO:0044452)
0.0 3.4 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 0.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.4 GO:0002080 acrosomal membrane(GO:0002080)
0.0 1.3 GO:0005875 microtubule associated complex(GO:0005875)
0.0 1.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.3 GO:0000346 transcription export complex(GO:0000346)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.7 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.7 GO:0044306 neuron projection terminus(GO:0044306)
0.0 0.1 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.6 GO:0034707 chloride channel complex(GO:0034707)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 10.9 GO:0015057 thrombin receptor activity(GO:0015057)
1.9 7.7 GO:0046624 sphingolipid transporter activity(GO:0046624)
1.7 8.6 GO:0042610 CD8 receptor binding(GO:0042610)
1.6 13.0 GO:0050786 RAGE receptor binding(GO:0050786)
1.6 7.9 GO:0030621 U4 snRNA binding(GO:0030621)
1.5 13.2 GO:0033691 sialic acid binding(GO:0033691)
1.4 4.3 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
1.4 5.5 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
1.2 11.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
1.2 19.9 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
1.2 12.7 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
1.1 4.5 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
1.1 1.1 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
1.0 2.9 GO:0070140 isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140)
0.9 3.7 GO:0004974 leukotriene receptor activity(GO:0004974)
0.9 2.6 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.9 6.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.8 8.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.8 2.5 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.8 4.7 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.8 2.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.8 4.6 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.8 6.8 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.7 3.0 GO:0004127 cytidylate kinase activity(GO:0004127)
0.7 3.7 GO:0070051 fibrinogen binding(GO:0070051)
0.7 2.2 GO:0035500 MH2 domain binding(GO:0035500)
0.7 2.9 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.7 5.9 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.7 2.2 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.7 2.8 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.7 4.1 GO:1990932 5.8S rRNA binding(GO:1990932)
0.7 7.5 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.7 3.3 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.7 2.0 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.6 2.5 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.6 12.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.6 3.7 GO:0032027 myosin light chain binding(GO:0032027)
0.6 3.0 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.6 1.2 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.6 5.8 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.6 10.1 GO:0008179 adenylate cyclase binding(GO:0008179)
0.5 9.3 GO:0015643 toxic substance binding(GO:0015643)
0.5 1.6 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.5 1.6 GO:0004967 glucagon receptor activity(GO:0004967)
0.5 1.6 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.5 4.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.5 1.6 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.5 6.7 GO:0005522 profilin binding(GO:0005522)
0.5 5.6 GO:0050700 CARD domain binding(GO:0050700)
0.5 1.5 GO:0052743 inositol tetrakisphosphate phosphatase activity(GO:0052743)
0.5 16.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.5 4.9 GO:0051434 BH3 domain binding(GO:0051434)
0.5 1.5 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.5 1.9 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.5 1.4 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.5 1.9 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.5 2.3 GO:0004966 galanin receptor activity(GO:0004966)
0.5 6.9 GO:0008301 DNA binding, bending(GO:0008301)
0.5 2.8 GO:0051425 PTB domain binding(GO:0051425)
0.4 4.0 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.4 1.8 GO:0000010 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.4 2.9 GO:1990446 U1 snRNP binding(GO:1990446)
0.4 2.9 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.4 3.3 GO:0004064 arylesterase activity(GO:0004064)
0.4 4.1 GO:0008527 taste receptor activity(GO:0008527)
0.4 9.7 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.4 2.0 GO:0043532 angiostatin binding(GO:0043532)
0.4 3.3 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.4 0.7 GO:0002135 CTP binding(GO:0002135)
0.4 2.2 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.4 6.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.4 1.4 GO:0001069 regulatory region RNA binding(GO:0001069)
0.3 9.8 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.3 10.0 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.3 1.4 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700)
0.3 0.7 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.3 4.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.3 1.0 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.3 3.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.3 6.5 GO:0001618 virus receptor activity(GO:0001618)
0.3 1.3 GO:0046923 ER retention sequence binding(GO:0046923)
0.3 2.6 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.3 4.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.3 1.2 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.3 1.5 GO:0043515 kinetochore binding(GO:0043515)
0.3 1.8 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.3 1.5 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.3 4.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.3 56.7 GO:0008201 heparin binding(GO:0008201)
0.3 6.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.3 1.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.3 5.8 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.3 0.8 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.3 2.7 GO:0017070 U6 snRNA binding(GO:0017070)
0.3 1.9 GO:0045322 unmethylated CpG binding(GO:0045322)
0.3 5.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.3 1.3 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.3 12.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.3 0.8 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.3 1.5 GO:0033592 RNA strand annealing activity(GO:0033592)
0.2 2.2 GO:0043208 glycosphingolipid binding(GO:0043208)
0.2 2.0 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.2 0.7 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.2 1.0 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.2 8.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.2 2.5 GO:0031014 troponin T binding(GO:0031014)
0.2 4.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 1.5 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.2 5.1 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 0.7 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.2 3.8 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.2 0.9 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.2 0.9 GO:1990460 leptin receptor binding(GO:1990460)
0.2 9.4 GO:0042169 SH2 domain binding(GO:0042169)
0.2 1.5 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.2 2.5 GO:0051525 NFAT protein binding(GO:0051525)
0.2 5.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 1.8 GO:0051400 BH domain binding(GO:0051400)
0.2 2.9 GO:0004016 adenylate cyclase activity(GO:0004016)
0.2 7.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 1.4 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 9.8 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.2 5.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 0.8 GO:0003883 CTP synthase activity(GO:0003883)
0.2 31.5 GO:0017124 SH3 domain binding(GO:0017124)
0.2 0.8 GO:0070976 calcium-independent protein kinase C activity(GO:0004699) TIR domain binding(GO:0070976)
0.2 1.9 GO:0030274 LIM domain binding(GO:0030274)
0.2 4.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.2 2.8 GO:0019865 immunoglobulin binding(GO:0019865)
0.2 2.9 GO:0031432 titin binding(GO:0031432)
0.2 0.5 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.2 1.4 GO:0043047 single-stranded telomeric DNA binding(GO:0043047) G-rich strand telomeric DNA binding(GO:0098505)
0.2 0.5 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.2 1.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.2 1.6 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 9.8 GO:0030507 spectrin binding(GO:0030507)
0.2 2.8 GO:0035174 histone serine kinase activity(GO:0035174)
0.2 2.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 5.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 2.0 GO:0008097 5S rRNA binding(GO:0008097)
0.2 0.8 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.2 1.8 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.2 11.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.2 3.2 GO:0032183 SUMO binding(GO:0032183)
0.2 1.7 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 1.8 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 1.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 1.0 GO:0004969 histamine receptor activity(GO:0004969)
0.1 2.1 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 1.4 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.1 1.5 GO:0051861 glycolipid binding(GO:0051861)
0.1 1.4 GO:0050733 RS domain binding(GO:0050733)
0.1 1.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 1.9 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.5 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.4 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.5 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.1 0.4 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.1 5.5 GO:0003785 actin monomer binding(GO:0003785)
0.1 2.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 0.9 GO:0019808 polyamine binding(GO:0019808)
0.1 0.8 GO:1903136 copper chaperone activity(GO:0016531) cuprous ion binding(GO:1903136)
0.1 1.0 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 8.4 GO:0008026 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) ATP-dependent helicase activity(GO:0008026) RNA-dependent ATPase activity(GO:0008186) purine NTP-dependent helicase activity(GO:0070035)
0.1 0.8 GO:0036310 annealing helicase activity(GO:0036310)
0.1 0.2 GO:0031493 nucleosomal histone binding(GO:0031493)
0.1 0.5 GO:0019976 interleukin-2 binding(GO:0019976)
0.1 2.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.5 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 1.2 GO:0008417 fucosyltransferase activity(GO:0008417)
0.1 0.4 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.1 1.4 GO:0042162 telomeric DNA binding(GO:0042162)
0.1 0.8 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.5 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.3 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.6 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.4 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 3.3 GO:0019843 rRNA binding(GO:0019843)
0.1 0.8 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 1.3 GO:0001091 RNA polymerase II basal transcription factor binding(GO:0001091)
0.1 1.4 GO:0070063 RNA polymerase binding(GO:0070063)
0.1 0.4 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 0.3 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.1 0.8 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 4.9 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 0.3 GO:0001098 basal transcription machinery binding(GO:0001098) basal RNA polymerase II transcription machinery binding(GO:0001099)
0.1 2.0 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 3.8 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 4.1 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 0.7 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 3.0 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.1 GO:0070990 snRNP binding(GO:0070990)
0.1 2.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 3.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 28.4 GO:0030695 GTPase regulator activity(GO:0030695)
0.1 3.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.4 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 8.1 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.1 0.7 GO:0001727 lipid kinase activity(GO:0001727)
0.1 2.2 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 0.7 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.1 10.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.8 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 2.5 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 1.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 8.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.2 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.1 0.7 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 2.0 GO:0003777 microtubule motor activity(GO:0003777)
0.1 1.9 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.1 0.2 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.4 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 2.6 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899) RNA polymerase activity(GO:0034062)
0.1 1.1 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.2 GO:0034452 dynactin binding(GO:0034452)
0.1 1.7 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.8 GO:0015197 peptide transporter activity(GO:0015197)
0.1 1.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 0.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 1.0 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.4 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 2.9 GO:0097110 scaffold protein binding(GO:0097110)
0.0 1.9 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.0 0.9 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.3 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0030984 kininogen binding(GO:0030984)
0.0 0.8 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 1.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 2.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.2 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.2 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.5 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 1.4 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 2.8 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.7 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.1 GO:0001031 RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) 5S rDNA binding(GO:0080084)
0.0 0.4 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.0 2.2 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.2 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033) chromo shadow domain binding(GO:0070087)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 1.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.7 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 0.2 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.0 0.1 GO:0089720 caspase binding(GO:0089720)
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 2.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 2.1 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.7 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.6 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 1.0 GO:0005109 frizzled binding(GO:0005109)
0.0 0.9 GO:0003774 motor activity(GO:0003774)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.2 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.0 0.2 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.2 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.9 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.0 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.0 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 1.2 GO:0042393 histone binding(GO:0042393)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 29.8 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.7 10.0 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.6 30.7 PID IL23 PATHWAY IL23-mediated signaling events
0.6 9.9 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.6 23.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.5 23.6 PID AURORA B PATHWAY Aurora B signaling
0.5 32.4 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.4 19.2 PID ATR PATHWAY ATR signaling pathway
0.4 12.0 PID AURORA A PATHWAY Aurora A signaling
0.3 5.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.3 2.3 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.3 2.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.3 6.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.3 11.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.3 5.1 PID LPA4 PATHWAY LPA4-mediated signaling events
0.3 5.8 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.3 10.8 PID BCR 5PATHWAY BCR signaling pathway
0.3 26.8 PID CMYB PATHWAY C-MYB transcription factor network
0.2 7.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.2 2.4 PID EPHB FWD PATHWAY EPHB forward signaling
0.2 4.0 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.2 11.8 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.2 5.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 5.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.2 7.5 PID IL4 2PATHWAY IL4-mediated signaling events
0.2 0.5 PID ERBB4 PATHWAY ErbB4 signaling events
0.2 2.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 4.9 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.2 7.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.2 0.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 2.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 6.0 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 3.9 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 3.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 6.7 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 1.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 3.5 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 11.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 4.6 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 5.1 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 2.2 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 1.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 1.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 2.1 PID CD40 PATHWAY CD40/CD40L signaling
0.1 3.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 19.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 1.5 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 1.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 1.3 PID MYC PATHWAY C-MYC pathway
0.1 2.6 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 1.9 PID RHOA PATHWAY RhoA signaling pathway
0.1 17.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 4.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 1.0 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 0.5 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 0.2 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.1 2.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 0.4 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 2.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.0 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.7 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.4 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 1.0 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.8 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.3 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.1 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.1 PID FOXO PATHWAY FoxO family signaling
0.0 0.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.3 PID INSULIN PATHWAY Insulin Pathway
0.0 0.2 PID ARF 3PATHWAY Arf1 pathway
0.0 0.2 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.0 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.9 13.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.8 6.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.8 7.0 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.7 13.0 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.6 11.4 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.6 6.5 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.6 32.6 REACTOME G PROTEIN BETA GAMMA SIGNALLING Genes involved in G-protein beta:gamma signalling
0.6 7.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.6 10.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.6 6.7 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.6 1.1 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.5 3.1 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.4 5.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.4 9.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.4 5.9 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.4 19.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.4 2.8 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.4 5.8 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.4 13.8 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.4 1.8 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.3 5.1 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.3 8.9 REACTOME KINESINS Genes involved in Kinesins
0.3 4.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.3 7.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.3 8.0 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.3 33.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.3 7.3 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.3 1.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.3 2.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.3 5.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.3 8.9 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.3 3.0 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.3 1.6 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.2 3.7 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2 5.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.2 4.9 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.2 9.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 2.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 8.0 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.2 1.8 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.2 6.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 1.1 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.2 5.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.2 4.7 REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION Genes involved in Cleavage of Growing Transcript in the Termination Region
0.2 33.2 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.2 6.3 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.2 1.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2 1.7 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.2 6.0 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 1.4 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.1 5.9 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.1 2.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 1.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.9 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 5.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 5.2 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 2.7 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 4.9 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.0 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 1.7 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 4.2 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.1 2.8 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 0.8 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.1 0.5 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 5.3 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.1 5.6 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.8 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1 0.4 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 1.4 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 1.3 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1 1.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 3.0 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 0.1 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.1 0.9 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.0 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 0.5 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.9 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 1.5 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.4 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 1.0 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 2.5 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.3 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.6 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.8 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.1 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.8 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 3.7 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.6 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.0 0.8 REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0 0.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.1 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.3 REACTOME DEADENYLATION DEPENDENT MRNA DECAY Genes involved in Deadenylation-dependent mRNA decay
0.0 0.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.6 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.1 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.4 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation