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GSE58827: Dynamics of the Mouse Liver

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Results for En2

Z-value: 0.89

Motif logo

Transcription factors associated with En2

Gene Symbol Gene ID Gene Info
ENSMUSG00000039095.7 engrailed 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
En2mm10_v2_chr5_+_28165690_28165717-0.289.4e-02Click!

Activity profile of En2 motif

Sorted Z-values of En2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_127898515 9.28 ENSMUST00000047134.7
4short chain dehydrogenase/reductase family 9C, member 7
chr3_+_60081861 5.10 ENSMUST00000029326.5
succinate receptor 1
chr10_-_109010955 4.28 ENSMUST00000105276.1
ENSMUST00000064054.7
synaptotagmin I
chr19_-_7966000 4.14 ENSMUST00000182102.1
ENSMUST00000075619.4
solute carrier family 22, member 27
chr2_-_148045891 3.38 ENSMUST00000109964.1
forkhead box A2
chr1_+_127729405 3.36 ENSMUST00000038006.6
amino carboxymuconate semialdehyde decarboxylase
chr5_+_135106881 3.15 ENSMUST00000005507.3
MLX interacting protein-like
chr17_-_83846769 3.05 ENSMUST00000000687.7
3-hydroxyanthranilate 3,4-dioxygenase
chr14_+_33941021 2.94 ENSMUST00000100720.1
growth differentiation factor 2
chr12_-_84450944 2.91 ENSMUST00000085192.5
aldehyde dehydrogenase family 6, subfamily A1
chr14_+_55560480 2.84 ENSMUST00000121622.1
ENSMUST00000143431.1
ENSMUST00000150481.1
DDB1 and CUL4 associated factor 11
chr14_+_55560904 2.59 ENSMUST00000072530.4
ENSMUST00000128490.1
DDB1 and CUL4 associated factor 11
chr6_-_54992946 2.58 ENSMUST00000131475.1
gamma-glutamyl cyclotransferase
chr7_+_44590886 2.55 ENSMUST00000107906.3
potassium voltage gated channel, Shaw-related subfamily, member 3
chr5_-_77115145 2.53 ENSMUST00000081964.5
HOP homeobox
chr8_-_45382198 2.53 ENSMUST00000093526.6
family with sequence similarity 149, member A
chr3_+_62419668 2.46 ENSMUST00000161057.1
Rho guanine nucleotide exchange factor (GEF) 26
chrM_+_10167 2.34 ENSMUST00000082414.1
mitochondrially encoded NADH dehydrogenase 4
chr17_+_35424870 2.29 ENSMUST00000113879.3
histocompatibility 2, Q region locus 6
chr2_+_30364262 2.27 ENSMUST00000142801.1
ENSMUST00000100214.3
family with sequence similarity 73, member B
chr2_+_30364227 2.20 ENSMUST00000077977.7
ENSMUST00000140075.2
family with sequence similarity 73, member B
chr13_-_23574196 2.14 ENSMUST00000105106.1
histone cluster 1, H2bf
chr8_-_83955205 2.14 ENSMUST00000098595.2
predicted gene 10644
chr10_-_92375367 2.04 ENSMUST00000182870.1
predicted gene, 20757
chr18_+_84851338 2.02 ENSMUST00000160180.1
cytochrome b-5
chr2_+_109917639 2.01 ENSMUST00000046548.7
ENSMUST00000111037.2
leucine-rich repeat-containing G protein-coupled receptor 4
chr17_+_35424842 1.99 ENSMUST00000174699.1
histocompatibility 2, Q region locus 6
chr15_+_100353149 1.97 ENSMUST00000075675.5
ENSMUST00000088142.5
ENSMUST00000176287.1
cDNA sequence AB099516
methyltransferase like 7A2
chrM_+_7005 1.93 ENSMUST00000082405.1
mitochondrially encoded cytochrome c oxidase II
chr6_-_146502141 1.91 ENSMUST00000079573.6
ENSMUST00000139732.1
inositol 1,4,5-triphosphate receptor 2
chr4_-_129261394 1.88 ENSMUST00000145261.1
expressed sequence C77080
chr9_-_71163224 1.86 ENSMUST00000074465.2
aquaporin 9
chr17_-_34959232 1.83 ENSMUST00000165202.1
ENSMUST00000172753.1
heat shock protein 1B
chr2_+_118861954 1.78 ENSMUST00000028807.5
isovaleryl coenzyme A dehydrogenase
chrM_+_9870 1.77 ENSMUST00000084013.1
mitochondrially encoded NADH dehydrogenase 4L
chr6_+_37870786 1.75 ENSMUST00000120428.1
ENSMUST00000031859.7
tripartite motif-containing 24
chr10_+_39612934 1.75 ENSMUST00000019987.6
TRAF3 interacting protein 2
chr18_+_38993126 1.72 ENSMUST00000097593.2
Rho GTPase activating protein 26
chrM_+_3906 1.71 ENSMUST00000082396.1
mitochondrially encoded NADH dehydrogenase 2
chr4_-_63154130 1.62 ENSMUST00000030041.4
alpha 1 microglobulin/bikunin
chr14_+_55559993 1.61 ENSMUST00000117236.1
DDB1 and CUL4 associated factor 11
chr17_-_36032682 1.61 ENSMUST00000102678.4
histocompatibility 2, T region locus 23
chr6_-_126645784 1.61 ENSMUST00000055168.3
potassium voltage-gated channel, shaker-related subfamily, member 1
chr17_-_34305715 1.60 ENSMUST00000174074.1
predicted gene 20513
chr19_+_25406661 1.60 ENSMUST00000146647.1
KN motif and ankyrin repeat domains 1
chr10_-_127121125 1.59 ENSMUST00000164259.1
ENSMUST00000080975.4
amplified in osteosarcoma
chr11_-_71019233 1.59 ENSMUST00000108523.3
ENSMUST00000143850.1
Der1-like domain family, member 2
chr15_-_101892916 1.57 ENSMUST00000100179.1
keratin 76
chr2_+_116067213 1.55 ENSMUST00000152412.1
RIKEN cDNA G630016G05 gene
chr18_+_56432116 1.54 ENSMUST00000070166.5
GRAM domain containing 3
chr14_+_55560010 1.54 ENSMUST00000147981.1
ENSMUST00000133256.1
DDB1 and CUL4 associated factor 11
chr5_-_137684665 1.52 ENSMUST00000100544.4
ENSMUST00000031736.9
ENSMUST00000151839.1
ArfGAP with FG repeats 2
chr7_+_64501687 1.46 ENSMUST00000032732.8
amyloid beta (A4) precursor protein-binding, family A, member 2
chr2_+_20737306 1.42 ENSMUST00000114606.1
ENSMUST00000114608.1
enhancer trap locus 4
chr10_-_107486077 1.36 ENSMUST00000000445.1
myogenic factor 5
chrX_-_60893430 1.35 ENSMUST00000135107.2
SRY-box containing gene 3
chr7_-_119895446 1.35 ENSMUST00000098080.2
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr16_+_38089001 1.33 ENSMUST00000023507.6
glycogen synthase kinase 3 beta
chr1_+_132298606 1.33 ENSMUST00000046071.4
kelch domain containing 8A
chr3_+_108653931 1.31 ENSMUST00000029483.8
ENSMUST00000124384.1
chloride channel CLIC-like 1
chrX_+_57212110 1.30 ENSMUST00000033466.1
CD40 ligand
chr5_-_62766153 1.29 ENSMUST00000076623.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr17_-_12960306 1.28 ENSMUST00000159697.1
acetyl-Coenzyme A acetyltransferase 2
chr11_-_86993682 1.27 ENSMUST00000018571.4
yippee-like 2 (Drosophila)
chr12_-_56613270 1.27 ENSMUST00000072631.5
NK2 homeobox 9
chr14_-_55560340 1.26 ENSMUST00000066106.3
RIKEN cDNA A730061H03 gene
chr17_+_3397189 1.26 ENSMUST00000072156.6
T cell lymphoma invasion and metastasis 2
chrM_+_9452 1.24 ENSMUST00000082411.1
mitochondrially encoded NADH dehydrogenase 3
chr9_+_104063678 1.20 ENSMUST00000047799.5
acyl-Coenzyme A dehydrogenase family, member 11
chr4_+_150853919 1.20 ENSMUST00000073600.2
ERBB receptor feedback inhibitor 1
chrX_+_129749740 1.19 ENSMUST00000167619.2
ENSMUST00000037854.8
diaphanous homolog 2 (Drosophila)
chr9_+_43829963 1.17 ENSMUST00000180221.1
predicted gene 3898
chr16_+_22857845 1.15 ENSMUST00000004574.7
ENSMUST00000178320.1
ENSMUST00000166487.2
DnaJ (Hsp40) homolog, subfamily B, member 11
chr13_-_23710714 1.14 ENSMUST00000091707.6
ENSMUST00000006787.7
ENSMUST00000091706.6
hemochromatosis
chr2_-_173276144 1.12 ENSMUST00000139306.1
prostate transmembrane protein, androgen induced 1
chr3_-_79841729 1.11 ENSMUST00000168038.1
transmembrane protein 144
chr5_-_62765618 1.10 ENSMUST00000159470.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr11_-_118212715 1.10 ENSMUST00000106302.2
ENSMUST00000151165.1
cytohesin 1
chr13_+_34734837 1.10 ENSMUST00000039605.6
family with sequence similarity 50, member B
chrM_+_7759 1.08 ENSMUST00000082407.1
ENSMUST00000082408.1
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr7_+_64502090 1.07 ENSMUST00000137732.1
amyloid beta (A4) precursor protein-binding, family A, member 2
chr4_+_150237694 1.04 ENSMUST00000141931.1
enolase 1, alpha non-neuron
chr8_-_70139197 1.02 ENSMUST00000075724.7
regulatory factor X-associated ankyrin-containing protein
chr3_-_32491969 1.01 ENSMUST00000164954.1
potassium large conductance calcium-activated channel, subfamily M, beta member 3
chrM_+_8600 1.00 ENSMUST00000082409.1
mitochondrially encoded cytochrome c oxidase III
chr12_-_91849081 0.99 ENSMUST00000167466.1
ENSMUST00000021347.5
ENSMUST00000178462.1
sel-1 suppressor of lin-12-like (C. elegans)
chr7_+_5015466 0.99 ENSMUST00000086349.3
zinc finger protein 524
chrX_+_152001845 0.99 ENSMUST00000026289.3
ENSMUST00000112617.3
hydroxysteroid (17-beta) dehydrogenase 10
chr9_+_104063376 0.98 ENSMUST00000120854.1
acyl-Coenzyme A dehydrogenase family, member 11
chr11_+_99873389 0.97 ENSMUST00000093936.3
keratin associated protein 9-1
chr17_-_34972124 0.97 ENSMUST00000087328.2
ENSMUST00000179128.1
heat shock protein 1A
chr8_+_106150359 0.95 ENSMUST00000034377.6
phospholipase A2, group XV
chr7_+_103550368 0.95 ENSMUST00000106888.1
olfactory receptor 613
chr1_-_172632931 0.94 ENSMUST00000027826.5
dual specificity phosphatase 23
chr7_+_64501949 0.93 ENSMUST00000138829.1
amyloid beta (A4) precursor protein-binding, family A, member 2
chr3_-_92123943 0.93 ENSMUST00000070284.3
proline rich 9
chr9_+_78448192 0.91 ENSMUST00000034896.6
mitochondrial translation optimization 1 homolog (S. cerevisiae)
chr9_+_32116040 0.90 ENSMUST00000174641.1
Rho GTPase activating protein 32
chr19_-_6942406 0.90 ENSMUST00000099782.3
G protein-coupled receptor 137
chr19_-_3575708 0.89 ENSMUST00000113997.2
ENSMUST00000025846.8
ENSMUST00000172362.1
protein phosphatase 6, regulatory subunit 3
chr7_-_105399991 0.87 ENSMUST00000118726.1
ENSMUST00000074686.7
ENSMUST00000122327.1
ENSMUST00000179474.1
ENSMUST00000048079.6
family with sequence similarity 160, member A2
chr15_+_100334929 0.87 ENSMUST00000075420.4
methyltransferase like 7A3
chr15_+_100364542 0.87 ENSMUST00000175683.1
ENSMUST00000177211.1
ENSMUST00000108953.2
HIG1 domain family, member 1C
cDNA sequence AB099516
chr19_+_3851797 0.87 ENSMUST00000072055.6
choline kinase alpha
chr11_-_31671863 0.86 ENSMUST00000058060.7
biorientation of chromosomes in cell division 1
chr19_+_3851972 0.86 ENSMUST00000025760.6
choline kinase alpha
chr9_-_96719549 0.84 ENSMUST00000128269.1
zinc finger and BTB domain containing 38
chr5_-_74531619 0.84 ENSMUST00000113542.2
ENSMUST00000072857.6
ENSMUST00000121330.1
ENSMUST00000151474.1
Sec1 family domain containing 2
chr19_+_6046576 0.81 ENSMUST00000138532.1
ENSMUST00000129081.1
ENSMUST00000156550.1
synovial apoptosis inhibitor 1, synoviolin
chr4_-_14621669 0.81 ENSMUST00000143105.1
solute carrier family 26, member 7
chr5_+_88583527 0.81 ENSMUST00000031229.6
RUN and FYVE domain containing 3
chrX_+_160768179 0.81 ENSMUST00000112368.2
retinoschisis (X-linked, juvenile) 1 (human)
chr11_+_116843278 0.77 ENSMUST00000106370.3
methyltransferase like 23
chr7_+_102210335 0.77 ENSMUST00000140631.1
ENSMUST00000120879.1
ENSMUST00000146996.1
post-GPI attachment to proteins 2
chr9_+_21955747 0.77 ENSMUST00000053583.5
SWIM type zinc finger 7 associated protein 1
chr6_+_8948608 0.77 ENSMUST00000160300.1
neurexophilin 1
chr4_+_108719649 0.76 ENSMUST00000178992.1
RIKEN cDNA 3110021N24 gene
chr2_-_84715160 0.75 ENSMUST00000035840.5
zinc finger, DHHC domain containing 5
chrX_+_160768013 0.75 ENSMUST00000033650.7
retinoschisis (X-linked, juvenile) 1 (human)
chr14_+_53461099 0.75 ENSMUST00000181728.1
T cell receptor alpha variable 7-4
chr11_-_99374895 0.75 ENSMUST00000006963.2
keratin 28
chr19_-_28967794 0.73 ENSMUST00000162110.1
RIKEN cDNA 4430402I18 gene
chr8_+_94037198 0.73 ENSMUST00000109556.2
ENSMUST00000093301.2
ENSMUST00000060632.7
2-oxoglutarate and iron-dependent oxygenase domain containing 1
chrX_-_136741155 0.69 ENSMUST00000166930.1
ENSMUST00000113095.1
ENSMUST00000155207.1
ENSMUST00000080411.6
ENSMUST00000169418.1
mortality factor 4 like 2
chr11_+_75532099 0.69 ENSMUST00000169547.2
solute carrier family 43, member 2
chr16_+_45093611 0.68 ENSMUST00000099498.2
coiled-coil domain containing 80
chr11_-_99337930 0.68 ENSMUST00000100482.2
keratin 26
chrM_+_2743 0.66 ENSMUST00000082392.1
mitochondrially encoded NADH dehydrogenase 1
chr14_-_50681645 0.66 ENSMUST00000078075.4
olfactory receptor 747
chr2_-_146511899 0.66 ENSMUST00000131824.1
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr11_+_11114125 0.66 ENSMUST00000109681.1
von Willebrand factor C domain containing 2
chr7_+_79273201 0.66 ENSMUST00000037315.6
abhydrolase domain containing 2
chr17_+_45734506 0.64 ENSMUST00000180558.1
RIKEN cDNA F630040K05 gene
chr11_-_99322943 0.63 ENSMUST00000038004.2
keratin 25
chr9_+_107563246 0.62 ENSMUST00000010198.3
tumor suppressor candidate 2
chr10_+_59403644 0.62 ENSMUST00000009790.7
phospholipase A2, group XIIB
chr12_+_35047180 0.61 ENSMUST00000048519.9
ENSMUST00000163677.1
sorting nexin 13
chr7_-_99141068 0.60 ENSMUST00000037968.8
UV radiation resistance associated gene
chr4_+_42949814 0.58 ENSMUST00000037872.3
ENSMUST00000098112.2
DnaJ (Hsp40) homolog, subfamily B, member 5
chr8_-_84662841 0.57 ENSMUST00000060427.4
immediate early response 2
chr10_+_73821937 0.57 ENSMUST00000134009.2
ENSMUST00000125006.2
ENSMUST00000177420.1
protocadherin 15
chr12_-_104473236 0.57 ENSMUST00000021513.4
goosecoid homeobox
chr11_+_23306884 0.56 ENSMUST00000180046.1
ubiquitin specific peptidase 34
chr8_-_83594440 0.56 ENSMUST00000019382.9
ENSMUST00000165740.1
trans-2,3-enoyl-CoA reductase
chr14_+_52769753 0.55 ENSMUST00000178768.2
T cell receptor alpha variable 7D-4
chr11_-_31671727 0.53 ENSMUST00000109415.1
biorientation of chromosomes in cell division 1
chr4_-_14621494 0.53 ENSMUST00000149633.1
solute carrier family 26, member 7
chr12_-_91779129 0.53 ENSMUST00000170077.1
stonin 2
chr2_-_144527341 0.52 ENSMUST00000163701.1
ENSMUST00000081982.5
double zinc ribbon and ankyrin repeat domains 1
chr7_-_25754701 0.51 ENSMUST00000108401.1
ENSMUST00000043765.7
heterogeneous nuclear ribonucleoprotein U-like 1
chr10_-_40142247 0.50 ENSMUST00000092566.6
solute carrier family 16 (monocarboxylic acid transporters), member 10
chr1_-_131527302 0.49 ENSMUST00000097588.2
SLIT-ROBO Rho GTPase activating protein 2
chr8_-_83594405 0.47 ENSMUST00000163837.1
trans-2,3-enoyl-CoA reductase
chr5_-_106696530 0.47 ENSMUST00000137285.1
ENSMUST00000124263.1
ENSMUST00000112695.1
ENSMUST00000155495.1
ENSMUST00000135108.1
zinc finger protein 644
chr15_-_76243401 0.47 ENSMUST00000165738.1
ENSMUST00000075689.6
poly (ADP-ribose) polymerase family, member 10
chr2_-_17460610 0.47 ENSMUST00000145492.1
nebulette
chr15_-_101573883 0.46 ENSMUST00000042957.5
keratin 75
chr9_-_96719404 0.46 ENSMUST00000140121.1
zinc finger and BTB domain containing 38
chr10_+_73821857 0.45 ENSMUST00000177128.1
ENSMUST00000064562.7
ENSMUST00000129404.2
ENSMUST00000105426.3
ENSMUST00000131321.2
ENSMUST00000126920.2
ENSMUST00000147189.2
ENSMUST00000105424.3
ENSMUST00000092420.6
ENSMUST00000105429.3
ENSMUST00000131724.2
ENSMUST00000152655.2
ENSMUST00000151116.2
ENSMUST00000155701.2
ENSMUST00000152819.2
ENSMUST00000125517.2
ENSMUST00000124046.1
ENSMUST00000149977.2
ENSMUST00000146682.1
ENSMUST00000177107.1
protocadherin 15
chr5_-_106696819 0.45 ENSMUST00000127434.1
ENSMUST00000112696.1
ENSMUST00000112698.1
zinc finger protein 644
chr16_-_45724600 0.44 ENSMUST00000096057.4
transgelin 3
chr8_+_106603351 0.44 ENSMUST00000000312.5
ENSMUST00000167688.1
cadherin 1
chr8_+_13907748 0.44 ENSMUST00000043520.3
F-box protein 25
chr5_-_137531204 0.43 ENSMUST00000150063.2
guanine nucleotide binding protein (G protein), beta 2
chr1_+_131527901 0.42 ENSMUST00000068613.4
family with sequence similarity 72, member A
chr4_-_155056784 0.42 ENSMUST00000131173.2
phospholipase C, eta 2
chr15_+_80255184 0.42 ENSMUST00000109605.3
activating transcription factor 4
chr1_+_104768510 0.42 ENSMUST00000062528.8
cadherin 20
chr6_+_28480337 0.42 ENSMUST00000001460.7
ENSMUST00000167201.1
staphylococcal nuclease and tudor domain containing 1
chr8_-_90908415 0.41 ENSMUST00000098517.1
predicted gene 6658
chr11_+_120467635 0.40 ENSMUST00000140862.1
ENSMUST00000106205.1
ENSMUST00000106203.1
ENSMUST00000026900.7
HGF-regulated tyrosine kinase substrate
chr11_-_59839745 0.39 ENSMUST00000141415.1
COP9 (constitutive photomorphogenic) homolog, subunit 3 (Arabidopsis thaliana)
chr2_-_92540967 0.39 ENSMUST00000142249.2
predicted gene 13817
chr2_+_144527718 0.38 ENSMUST00000028914.2
ENSMUST00000110017.2
polymerase (RNA) III (DNA directed) polypeptide F
chrX_+_136741821 0.37 ENSMUST00000089350.4
cDNA sequence BC065397
chr13_-_92030897 0.37 ENSMUST00000149630.1
RAS protein-specific guanine nucleotide-releasing factor 2
chr8_-_84237042 0.37 ENSMUST00000039480.5
zinc finger SWIM-type containing 4
chrM_+_11734 0.36 ENSMUST00000082418.1
mitochondrially encoded NADH dehydrogenase 5
chr11_-_70687917 0.36 ENSMUST00000108545.2
ENSMUST00000120261.1
ENSMUST00000036299.7
ENSMUST00000119120.1
ENSMUST00000100933.3
calmodulin binding transcription activator 2
chr5_+_139543889 0.34 ENSMUST00000174792.1
ENSMUST00000031523.8
UNC homeobox
chr10_+_128337761 0.34 ENSMUST00000005826.7
citrate synthase
chr1_-_171287916 0.33 ENSMUST00000111305.1
ubiquitin specific peptidase 21
chr11_+_69059750 0.33 ENSMUST00000051888.2
RIKEN cDNA 2310047M10 gene
chr2_-_87492418 0.33 ENSMUST00000026957.3
preferentially expressed antigen in melanoma like 7
chr15_+_102406143 0.33 ENSMUST00000170884.1
ENSMUST00000165924.1
ENSMUST00000163709.1
ENSMUST00000001326.6
trans-acting transcription factor 1
chr1_-_171287931 0.32 ENSMUST00000111306.3
ENSMUST00000065941.5
ubiquitin specific peptidase 21
chr4_+_116221590 0.32 ENSMUST00000147292.1
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr5_-_84417359 0.31 ENSMUST00000113401.1
Eph receptor A5
chr11_-_70688097 0.30 ENSMUST00000108544.1
calmodulin binding transcription activator 2
chr12_-_85151264 0.30 ENSMUST00000019379.7
ribosomal protein S6 kinase-like 1
chr17_-_24886304 0.30 ENSMUST00000044252.5
nucleotide binding protein 2
chr4_+_136310936 0.29 ENSMUST00000131671.1
heterogeneous nuclear ribonucleoprotein R
chr12_+_84451485 0.29 ENSMUST00000137170.1
lin-52 homolog (C. elegans)
chr10_+_99263224 0.27 ENSMUST00000020118.4
dual specificity phosphatase 6
chr11_+_102285161 0.27 ENSMUST00000156326.1
transmembrane and ubiquitin-like domain containing 2
chr7_+_29071597 0.27 ENSMUST00000180926.1
predicted gene, 26604
chrX_+_102119447 0.27 ENSMUST00000113627.3
protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin)
chr19_+_6942501 0.27 ENSMUST00000113423.3
BCL2-associated agonist of cell death
chr17_+_20945311 0.26 ENSMUST00000007708.7
protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform
chr7_+_90380646 0.23 ENSMUST00000098310.2
synaptotagmin-like 2

Network of associatons between targets according to the STRING database.

First level regulatory network of En2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
1.0 2.9 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.8 6.4 GO:0046874 quinolinate metabolic process(GO:0046874)
0.7 2.0 GO:0061290 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.6 1.1 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589)
0.5 1.6 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.5 5.3 GO:0005513 detection of calcium ion(GO:0005513)
0.5 1.9 GO:0015851 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.4 3.1 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.4 1.3 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.4 1.3 GO:2001200 positive regulation of dendritic cell differentiation(GO:2001200)
0.4 1.6 GO:0002489 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.4 1.6 GO:0050975 sensory perception of touch(GO:0050975)
0.4 1.6 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.3 1.0 GO:0050973 detection of mechanical stimulus involved in equilibrioception(GO:0050973)
0.3 3.2 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.3 2.5 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.3 4.1 GO:0015747 urate transport(GO:0015747)
0.3 1.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.3 1.8 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.2 1.2 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.2 0.9 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.2 1.4 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.2 4.1 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 1.7 GO:0019695 choline metabolic process(GO:0019695)
0.2 0.6 GO:0052564 response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.2 1.8 GO:0006551 leucine metabolic process(GO:0006551)
0.2 1.3 GO:0019532 oxalate transport(GO:0019532)
0.2 1.1 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.2 0.5 GO:1900045 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.1 1.6 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.4 GO:0060066 oviduct development(GO:0060066)
0.1 1.9 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 1.0 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 2.9 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 0.6 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 1.3 GO:0030300 regulation of intestinal cholesterol absorption(GO:0030300)
0.1 2.1 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 0.7 GO:0060178 regulation of exocyst localization(GO:0060178)
0.1 0.3 GO:0006583 melanin biosynthetic process from tyrosine(GO:0006583)
0.1 1.6 GO:0048733 sebaceous gland development(GO:0048733)
0.1 0.4 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 2.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 4.3 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 2.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.3 GO:1902220 positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902220)
0.1 1.8 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 0.3 GO:1903538 meiotic sister chromatid cohesion, centromeric(GO:0051754) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.1 0.7 GO:0006449 regulation of translational termination(GO:0006449)
0.1 1.4 GO:0010225 response to UV-C(GO:0010225)
0.1 1.7 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.1 1.0 GO:0030497 fatty acid elongation(GO:0030497)
0.1 3.2 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.1 0.5 GO:0021815 modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
0.1 0.4 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.1 0.8 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.1 1.4 GO:0021854 hypothalamus development(GO:0021854)
0.0 1.2 GO:0016556 mRNA modification(GO:0016556)
0.0 0.6 GO:0014029 neural crest formation(GO:0014029)
0.0 0.4 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0 0.3 GO:0070814 hydrogen sulfide biosynthetic process(GO:0070814)
0.0 1.1 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 1.0 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 1.1 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.3 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.7 GO:0032570 response to progesterone(GO:0032570)
0.0 0.3 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 1.1 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 2.6 GO:0001836 release of cytochrome c from mitochondria(GO:0001836)
0.0 0.1 GO:1903632 positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
0.0 1.5 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.3 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.0 2.6 GO:0046928 regulation of neurotransmitter secretion(GO:0046928)
0.0 0.2 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.7 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 1.3 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 1.1 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 1.2 GO:0071385 cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.8 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.8 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.7 GO:0003299 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.7 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.7 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.6 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.4 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.4 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.9 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.3 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.3 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.5 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 1.3 GO:0006821 chloride transport(GO:0006821)
0.0 0.8 GO:0015807 L-amino acid transport(GO:0015807)
0.0 0.3 GO:0061157 mRNA destabilization(GO:0061157)
0.0 0.5 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.3 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.7 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.9 GO:0042612 MHC class I protein complex(GO:0042612)
0.4 3.4 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.3 1.8 GO:0005726 perichromatin fibrils(GO:0005726)
0.2 8.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.2 1.6 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.2 4.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 1.1 GO:1990357 terminal web(GO:1990357)
0.1 0.9 GO:0070695 FHF complex(GO:0070695)
0.1 1.0 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 1.3 GO:1990909 Wnt signalosome(GO:1990909)
0.1 0.4 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.1 9.1 GO:0070469 respiratory chain(GO:0070469)
0.1 1.5 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.1 1.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 1.6 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.7 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 2.6 GO:0030673 axolemma(GO:0030673)
0.1 2.0 GO:0045095 keratin filament(GO:0045095)
0.0 0.4 GO:0097433 dense body(GO:0097433)
0.0 1.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.5 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.4 GO:0016600 flotillin complex(GO:0016600)
0.0 2.1 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.3 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.7 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.9 GO:0001533 cornified envelope(GO:0001533)
0.0 4.0 GO:0072562 blood microparticle(GO:0072562)
0.0 1.5 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.3 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.0 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 1.1 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.3 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.3 GO:0071437 invadopodium(GO:0071437)
0.0 3.4 GO:0008021 synaptic vesicle(GO:0008021)
0.0 1.1 GO:0032420 stereocilium(GO:0032420)
0.0 1.6 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.4 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.3 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 1.1 GO:0005882 intermediate filament(GO:0005882)
0.0 7.8 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 2.5 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.0 1.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.0 GO:0035841 growing cell tip(GO:0035838) new growing cell tip(GO:0035841)
0.0 0.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 3.0 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.3 GO:0030348 syntaxin-3 binding(GO:0030348)
0.7 2.2 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.5 7.0 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.5 2.6 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.5 1.9 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.4 1.7 GO:0004104 cholinesterase activity(GO:0004104)
0.4 8.7 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.4 1.9 GO:0005350 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.3 8.1 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.3 4.1 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.3 1.8 GO:0034056 estrogen response element binding(GO:0034056)
0.2 1.3 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.1 1.6 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 3.0 GO:0019825 oxygen binding(GO:0019825)
0.1 2.0 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 1.0 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 1.0 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.7 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 0.5 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 1.0 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.1 1.0 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 1.8 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 1.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 1.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 2.0 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.7 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
0.1 3.4 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 0.3 GO:0003681 bent DNA binding(GO:0003681)
0.1 0.5 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.1 0.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 3.4 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 3.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.3 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1 1.3 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 2.9 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor(GO:0016620)
0.0 0.8 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.7 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 2.9 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.7 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.2 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.7 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 1.0 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 2.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 1.1 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.3 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 2.6 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 1.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.4 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 1.0 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 1.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 1.1 GO:0015144 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0 0.3 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.7 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 3.7 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.8 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 1.3 GO:0005254 chloride channel activity(GO:0005254)
0.0 1.6 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.1 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 2.0 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 1.2 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.1 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.9 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.0 0.3 GO:0004623 phospholipase A2 activity(GO:0004623)
0.0 0.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 1.6 GO:0002020 protease binding(GO:0002020)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 PID ALK1 PATHWAY ALK1 signaling events
0.1 1.9 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 1.6 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 3.4 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 3.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 1.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 2.4 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.0 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.9 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.7 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.3 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.8 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.0 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 1.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.4 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.3 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.4 6.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.3 5.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 1.9 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.2 1.9 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.7 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 4.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 1.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 1.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.0 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.5 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 1.1 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 1.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 1.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.2 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 1.8 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 1.0 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.3 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription