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GSE58827: Dynamics of the Mouse Liver

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Results for E2f4

Z-value: 2.93

Motif logo

Transcription factors associated with E2f4

Gene Symbol Gene ID Gene Info
ENSMUSG00000014859.8 E2F transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2f4mm10_v2_chr8_+_105297663_1052977420.945.0e-17Click!

Activity profile of E2f4 motif

Sorted Z-values of E2f4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_72438519 29.37 ENSMUST00000184604.1
meiosis-specific nuclear structural protein 1
chr9_+_72438534 27.71 ENSMUST00000034746.8
meiosis-specific nuclear structural protein 1
chr2_+_163054682 27.20 ENSMUST00000018005.3
myeloblastosis oncogene-like 2
chr4_+_134510999 25.35 ENSMUST00000105866.2
aurora kinase A and ninein interacting protein
chr18_-_34751502 24.23 ENSMUST00000060710.7
cell division cycle 25C
chr8_-_53638945 23.67 ENSMUST00000047768.4
nei like 3 (E. coli)
chr14_-_47418407 23.55 ENSMUST00000043296.3
discs, large (Drosophila) homolog-associated protein 5
chr4_-_132345715 23.17 ENSMUST00000084250.4
regulator of chromosome condensation 1
chr16_-_30310773 22.32 ENSMUST00000061190.6
glycoprotein 5 (platelet)
chr4_-_132345686 22.17 ENSMUST00000030726.6
regulator of chromosome condensation 1
chr14_-_87141114 22.02 ENSMUST00000168889.1
diaphanous homolog 3 (Drosophila)
chr19_+_6084983 21.24 ENSMUST00000025704.2
cell division cycle associated 5
chr6_+_124830217 20.98 ENSMUST00000131847.1
ENSMUST00000151674.1
cell division cycle associated 3
chr13_+_23535411 20.87 ENSMUST00000080859.5
histone cluster 1, H3g
chr14_-_87141206 20.41 ENSMUST00000022599.7
diaphanous homolog 3 (Drosophila)
chr10_-_88146867 19.31 ENSMUST00000164121.1
ENSMUST00000164803.1
ENSMUST00000168163.1
ENSMUST00000048518.9
PARP1 binding protein
chr1_-_169531343 18.41 ENSMUST00000028000.7
NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr3_-_54915867 17.96 ENSMUST00000070342.3
serine rich and transmembrane domain containing 1
chr1_-_189688074 17.68 ENSMUST00000171929.1
ENSMUST00000165962.1
centromere protein F
chr4_-_116123618 17.23 ENSMUST00000102704.3
ENSMUST00000102705.3
RAD54 like (S. cerevisiae)
chr17_-_25727364 15.97 ENSMUST00000170070.1
ENSMUST00000048054.7
CTF18, chromosome transmission fidelity factor 18
chr1_-_169531447 15.88 ENSMUST00000111368.1
NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr11_+_98907801 15.22 ENSMUST00000092706.6
cell division cycle 6
chr13_-_23745511 15.12 ENSMUST00000091752.2
histone cluster 1, H3c
chrX_+_8271381 14.94 ENSMUST00000033512.4
solute carrier family 38, member 5
chrX_+_8271133 14.82 ENSMUST00000127103.1
ENSMUST00000115591.1
solute carrier family 38, member 5
chr7_-_38107490 13.80 ENSMUST00000108023.3
cyclin E1
chr18_-_58209926 13.78 ENSMUST00000025497.6
fibrillin 2
chrX_+_8271642 13.06 ENSMUST00000115590.1
solute carrier family 38, member 5
chr9_-_123678782 13.05 ENSMUST00000170591.1
ENSMUST00000171647.1
solute carrier family 6 (neurotransmitter transporter), member 20A
chr4_-_133967235 12.15 ENSMUST00000123234.1
high mobility group nucleosomal binding domain 2
chr4_-_133967296 11.50 ENSMUST00000105893.1
high mobility group nucleosomal binding domain 2
chr13_-_73937761 11.30 ENSMUST00000022053.8
thyroid hormone receptor interactor 13
chr9_-_32344237 11.22 ENSMUST00000034533.5
potassium inwardly-rectifying channel, subfamily J, member 5
chr9_+_107950952 10.95 ENSMUST00000049348.3
TRAF-interacting protein
chr6_+_113531675 10.89 ENSMUST00000036340.5
ENSMUST00000101051.2
Fanconi anemia, complementation group D2
chr9_+_119937606 10.73 ENSMUST00000035100.5
tetratricopeptide repeat domain 21A
chr2_+_103970221 10.54 ENSMUST00000111140.2
ENSMUST00000111139.2
LIM domain only 2
chr15_-_76639840 10.37 ENSMUST00000166974.1
ENSMUST00000168185.1
tonsoku-like, DNA repair protein
chr11_-_101551837 10.23 ENSMUST00000017290.4
breast cancer 1
chr12_+_117843873 10.06 ENSMUST00000176735.1
ENSMUST00000177339.1
cell division cycle associated 7 like
chr1_-_33669745 9.82 ENSMUST00000027312.9
DNA primase, p58 subunit
chr1_+_86303221 9.68 ENSMUST00000113306.2
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr17_-_29237759 9.10 ENSMUST00000137727.1
ENSMUST00000024805.7
copine V
chr4_-_133967893 9.03 ENSMUST00000100472.3
ENSMUST00000136327.1
high mobility group nucleosomal binding domain 2
chr1_+_52630692 9.02 ENSMUST00000165859.1
transmembrane protein 194B
chr7_-_92874196 8.62 ENSMUST00000032877.9
RIKEN cDNA 4632434I11 gene
chr1_-_60043087 8.46 ENSMUST00000027172.6
islet cell autoantigen 1-like
chr11_+_16951371 8.35 ENSMUST00000109635.1
ENSMUST00000061327.1
F-box protein 48
chr18_+_34751803 8.26 ENSMUST00000181453.1
ENSMUST00000181641.1
RIKEN cDNA 2010110K18 gene
chr11_-_6606053 8.24 ENSMUST00000045713.3
NAC alpha domain containing
chr17_-_24251382 8.22 ENSMUST00000115390.3
cyclin F
chr18_+_56707725 8.14 ENSMUST00000025486.8
lamin B1
chr16_-_90727329 7.97 ENSMUST00000099554.4
MIS18 kinetochore protein homolog A (S. pombe)
chr12_+_106010263 7.24 ENSMUST00000021539.8
ENSMUST00000085026.4
ENSMUST00000072040.5
vaccinia related kinase 1
chr8_+_18595131 7.20 ENSMUST00000039412.8
microcephaly, primary autosomal recessive 1
chr5_+_88764983 7.16 ENSMUST00000031311.9
deoxycytidine kinase
chr1_-_57377476 6.61 ENSMUST00000181949.1
RIKEN cDNA 4930558J18 gene
chr2_+_106695594 6.48 ENSMUST00000016530.7
metallophosphoesterase domain containing 2
chr4_-_59783800 6.41 ENSMUST00000107526.1
ENSMUST00000095063.4
INTS3 and NABP interacting protein
chr4_-_133967953 6.24 ENSMUST00000102553.4
high mobility group nucleosomal binding domain 2
chr18_-_60848911 6.23 ENSMUST00000177172.1
ENSMUST00000175934.1
ENSMUST00000176630.1
Treacher Collins Franceschetti syndrome 1, homolog
chr8_+_18595526 6.18 ENSMUST00000146819.1
microcephaly, primary autosomal recessive 1
chr7_+_126781483 5.58 ENSMUST00000172352.1
ENSMUST00000094037.4
T-box 6
chr10_+_79997463 5.57 ENSMUST00000171637.1
ENSMUST00000043866.7
ATP-binding cassette, sub-family A (ABC1), member 7
chr10_-_117792663 5.54 ENSMUST00000167943.1
ENSMUST00000064848.5
nucleoporin 107
chr4_+_11558914 5.53 ENSMUST00000178703.1
ENSMUST00000095145.5
ENSMUST00000108306.2
ENSMUST00000070755.6
RAD54 homolog B (S. cerevisiae)
chr5_-_138172383 5.52 ENSMUST00000000505.9
minichromosome maintenance deficient 7 (S. cerevisiae)
chrX_+_164980592 5.44 ENSMUST00000101082.4
ENSMUST00000167446.1
ENSMUST00000057150.6
Fanconi anemia, complementation group B
chr4_-_44704006 5.26 ENSMUST00000146335.1
paired box gene 5
chr9_-_65580040 5.12 ENSMUST00000068944.7
pleckstrin homology domain containing, family O member 2
chr17_+_50698525 5.00 ENSMUST00000061681.7
predicted gene 7334
chrX_-_8074720 4.99 ENSMUST00000115636.3
ENSMUST00000115638.3
suppressor of variegation 3-9 homolog 1 (Drosophila)
chr2_+_129593528 4.89 ENSMUST00000049262.7
ENSMUST00000163034.1
ENSMUST00000160276.1
signal-regulatory protein alpha
chr15_+_12824815 4.75 ENSMUST00000169061.1
drosha, ribonuclease type III
chr15_+_12824841 4.72 ENSMUST00000090292.5
drosha, ribonuclease type III
chr12_-_118198917 4.62 ENSMUST00000084806.6
dynein, axonemal, heavy chain 11
chr6_-_56704673 4.59 ENSMUST00000170382.2
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr9_+_44334685 4.52 ENSMUST00000052686.2
H2A histone family, member X
chrX_+_162901226 4.51 ENSMUST00000101095.2
cytidine 5'-triphosphate synthase 2
chrX_+_105079735 4.42 ENSMUST00000033577.4
polysaccharide biosynthesis domain containing 1
chr2_-_166713758 4.34 ENSMUST00000036719.5
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr1_-_77515048 4.34 ENSMUST00000027451.6
Eph receptor A4
chr2_+_30286406 4.23 ENSMUST00000138666.1
ENSMUST00000113634.2
nucleoporin 188
chrX_-_167209149 4.16 ENSMUST00000112176.1
thymosin, beta 4, X chromosome
chr12_+_99884498 4.15 ENSMUST00000153627.1
tyrosyl-DNA phosphodiesterase 1
chr2_+_129593195 4.03 ENSMUST00000099113.3
ENSMUST00000103202.3
signal-regulatory protein alpha
chr9_+_44134562 3.95 ENSMUST00000034650.8
ENSMUST00000098852.2
melanoma cell adhesion molecule
chr5_-_138171813 3.93 ENSMUST00000155902.1
ENSMUST00000148879.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr5_-_25705791 3.81 ENSMUST00000030773.7
X-ray repair complementing defective repair in Chinese hamster cells 2
chr7_+_58658181 3.74 ENSMUST00000168747.1
ATPase, class V, type 10A
chr14_-_54517353 3.67 ENSMUST00000023873.5
protein arginine N-methyltransferase 5
chrX_+_162901567 3.65 ENSMUST00000112303.1
ENSMUST00000033727.7
cytidine 5'-triphosphate synthase 2
chr9_-_83441065 3.64 ENSMUST00000034791.8
ENSMUST00000034793.8
Leber congenital amaurosis 5 (human)
chr5_-_33652296 3.61 ENSMUST00000151081.1
ENSMUST00000101354.3
stem-loop binding protein
chr10_+_127677064 3.47 ENSMUST00000118612.1
ENSMUST00000048099.4
transmembrane protein 194
chr2_+_181319714 3.43 ENSMUST00000098971.4
ENSMUST00000054622.8
ENSMUST00000108814.1
ENSMUST00000048608.9
ENSMUST00000108815.1
regulator of telomere elongation helicase 1
chr7_-_127208423 3.41 ENSMUST00000120705.1
TBC1 domain family, member 10b
chr17_+_87975044 3.36 ENSMUST00000005503.3
mutS homolog 6 (E. coli)
chr5_-_33652339 3.28 ENSMUST00000075670.6
stem-loop binding protein
chr2_+_181319806 3.23 ENSMUST00000153112.1
regulator of telomere elongation helicase 1
chr1_+_9798123 3.16 ENSMUST00000168907.1
ENSMUST00000166384.1
serum/glucocorticoid regulated kinase 3
chrX_-_78583882 3.14 ENSMUST00000114025.1
ENSMUST00000134602.1
ENSMUST00000114024.2
proline rich Gla (G-carboxyglutamic acid) 1
chr19_+_46075842 3.13 ENSMUST00000165017.1
nucleolar and coiled-body phosphoprotein 1
chr7_+_97371604 3.12 ENSMUST00000098300.4
asparagine-linked glycosylation 8 (alpha-1,3-glucosyltransferase)
chr10_+_88146992 3.10 ENSMUST00000052355.7
nucleoporin 37
chr2_+_153649617 3.03 ENSMUST00000109771.1
DNA methyltransferase 3B
chr4_-_58553311 2.96 ENSMUST00000107571.1
ENSMUST00000055018.4
lysophosphatidic acid receptor 1
chrX_+_162901762 2.87 ENSMUST00000112302.1
ENSMUST00000112301.1
cytidine 5'-triphosphate synthase 2
chr4_-_58553553 2.86 ENSMUST00000107575.2
ENSMUST00000107574.1
ENSMUST00000147354.1
lysophosphatidic acid receptor 1
chr9_+_57708534 2.80 ENSMUST00000043990.7
ENSMUST00000142807.1
enhancer of mRNA decapping 3 homolog (S. cerevisiae)
chr14_+_76488436 2.77 ENSMUST00000101618.2
TSC22 domain family, member 1
chr5_+_30889326 2.77 ENSMUST00000124908.1
ATP/GTP binding protein-like 5
chr11_+_108425192 2.70 ENSMUST00000150863.2
ENSMUST00000061287.5
ENSMUST00000149683.2
centrosomal protein 112
chr4_-_43562397 2.68 ENSMUST00000030187.7
talin 1
chr10_+_88147061 2.65 ENSMUST00000169309.1
nucleoporin 37
chr2_+_129592914 2.65 ENSMUST00000103203.1
signal-regulatory protein alpha
chr19_-_5366626 2.49 ENSMUST00000025762.8
barrier to autointegration factor 1
chr5_+_141241490 2.45 ENSMUST00000085774.4
sidekick homolog 1 (chicken)
chr17_-_35046726 2.31 ENSMUST00000097338.4
mutS homolog 5 (E. coli)
chr13_+_73937799 2.27 ENSMUST00000099384.2
bromodomain containing 9
chr12_-_4233958 2.15 ENSMUST00000111169.3
ENSMUST00000020981.5
centromere protein O
chr1_+_134415414 2.04 ENSMUST00000112237.1
adiponectin receptor 1
chr15_-_98831498 2.03 ENSMUST00000168846.1
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr9_-_82975475 2.00 ENSMUST00000034787.5
pleckstrin homology domain interacting protein
chr7_+_6383310 1.87 ENSMUST00000081022.7
zinc finger protein 28
chr17_+_29490812 1.87 ENSMUST00000024811.6
proviral integration site 1
chrX_-_78583782 1.76 ENSMUST00000177904.1
proline rich Gla (G-carboxyglutamic acid) 1
chr8_+_124023394 1.67 ENSMUST00000034457.8
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr17_-_17624458 1.66 ENSMUST00000041047.2
leucyl/cystinyl aminopeptidase
chr9_-_60688118 1.52 ENSMUST00000114034.2
ENSMUST00000065603.5
leucine rich repeat containing 49
chr4_-_3835595 1.49 ENSMUST00000138502.1
ribosomal protein S20
chr2_-_3512746 1.45 ENSMUST00000056700.7
ENSMUST00000027961.5
heat shock protein 14
heat shock protein 14
chr4_+_84884418 1.44 ENSMUST00000169371.2
centlein, centrosomal protein
chr5_+_21372642 1.35 ENSMUST00000035799.5
fibrinogen-like protein 2
chr7_+_24884651 1.33 ENSMUST00000153451.2
ENSMUST00000108429.1
ribosomal protein S19
chr6_+_70726430 1.25 ENSMUST00000103410.1
immunoglobulin kappa constant
chr14_+_55578123 1.24 ENSMUST00000174484.1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chrX_-_37110257 1.15 ENSMUST00000076265.6
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr17_+_34982099 1.13 ENSMUST00000007266.7
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr11_-_106999369 1.10 ENSMUST00000106768.1
ENSMUST00000144834.1
karyopherin (importin) alpha 2
chr4_+_44004438 1.09 ENSMUST00000107846.3
clathrin, light polypeptide (Lca)
chr4_-_132463873 1.08 ENSMUST00000102567.3
mediator of RNA polymerase II transcription, subunit 18 homolog (yeast)
chr1_+_133351909 1.05 ENSMUST00000112287.1
renin 1 structural
chr4_+_84884276 1.04 ENSMUST00000047023.6
centlein, centrosomal protein
chr11_-_106999482 1.02 ENSMUST00000018506.6
karyopherin (importin) alpha 2
chr5_-_92348871 1.00 ENSMUST00000038816.6
ENSMUST00000118006.1
chemokine (C-X-C motif) ligand 10
chr7_+_24884611 0.89 ENSMUST00000108428.1
ribosomal protein S19
chr4_-_58553184 0.84 ENSMUST00000145361.1
lysophosphatidic acid receptor 1
chr7_-_16285454 0.83 ENSMUST00000174270.1
coiled-coil domain containing 9
chr1_+_33669816 0.82 ENSMUST00000051203.5
RIKEN cDNA 1700001G17 gene
chr7_-_16286010 0.80 ENSMUST00000145519.2
coiled-coil domain containing 9
chr17_+_34982154 0.79 ENSMUST00000173004.1
LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr2_-_145935014 0.77 ENSMUST00000001818.4
Crn, crooked neck-like 1 (Drosophila)
chr7_-_109865586 0.77 ENSMUST00000007423.5
ENSMUST00000106728.2
ENSMUST00000106729.1
signal peptide, CUB domain, EGF-like 2
chrY_+_90784738 0.73 ENSMUST00000179483.1
erythroid differentiation regulator 1
chr1_+_179803376 0.69 ENSMUST00000097454.2
predicted gene 10518
chr3_-_142881942 0.68 ENSMUST00000043812.8
protein kinase N2
chr17_-_87025353 0.66 ENSMUST00000024957.6
phosphatidylinositol glycan anchor biosynthesis, class F
chr11_+_26593241 0.63 ENSMUST00000089614.4
predicted gene 6899
chrX_+_170009892 0.49 ENSMUST00000180251.1
predicted gene, 21887
chrX_+_71981522 0.48 ENSMUST00000114569.1
fetal and adult testis expressed 1
chr5_+_30888852 0.47 ENSMUST00000069705.4
ENSMUST00000031057.8
ENSMUST00000046182.5
ENSMUST00000114704.1
ENSMUST00000061213.6
ENSMUST00000114696.1
ENSMUST00000114700.2
ATP/GTP binding protein-like 5
chr13_-_69533839 0.45 ENSMUST00000044081.7
PAP associated domain containing 7
chr2_+_174076296 0.45 ENSMUST00000155000.1
ENSMUST00000134876.1
ENSMUST00000147038.1
syntaxin 16
chr1_+_157412352 0.38 ENSMUST00000061537.5
RIKEN cDNA 2810025M15 gene
chr17_-_84187939 0.36 ENSMUST00000060366.6
zinc finger protein 36, C3H type-like 2
chr7_+_97579868 0.25 ENSMUST00000042399.7
ENSMUST00000107153.1
remodeling and spacing factor 1
chr2_+_71786923 0.23 ENSMUST00000112101.1
ENSMUST00000028522.3
integrin alpha 6
chr9_+_92250039 0.22 ENSMUST00000093801.3
phospholipid scramblase 1
chr9_+_118926453 0.19 ENSMUST00000073109.5
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr17_-_35046539 0.15 ENSMUST00000007250.7
mutS homolog 5 (E. coli)
chr2_+_145934800 0.09 ENSMUST00000138774.1
ENSMUST00000152515.1
ENSMUST00000130168.1
ENSMUST00000133433.1
ENSMUST00000118002.1
RIKEN cDNA 4930529M08 gene
chrX_+_105079761 0.01 ENSMUST00000119477.1
polysaccharide biosynthesis domain containing 1
chr9_+_99456243 0.01 ENSMUST00000163199.2
RIKEN cDNA 1600029I14 gene

Network of associatons between targets according to the STRING database.

First level regulatory network of E2f4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.1 21.2 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
3.4 10.2 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
3.3 13.1 GO:0035524 proline transmembrane transport(GO:0035524)
2.9 54.7 GO:0070986 left/right axis specification(GO:0070986)
2.9 42.8 GO:0015816 glycine transport(GO:0015816)
2.8 13.8 GO:0071692 protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
2.7 8.1 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
2.5 9.8 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
2.2 13.4 GO:0060623 regulation of chromosome condensation(GO:0060623)
1.9 5.6 GO:1901074 regulation of engulfment of apoptotic cell(GO:1901074)
1.8 5.5 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
1.8 7.2 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
1.8 7.2 GO:0046125 pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
1.8 16.0 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
1.8 24.7 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
1.7 6.7 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
1.7 6.7 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990) negative regulation of t-circle formation(GO:1904430)
1.6 11.2 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914) potassium ion import across plasma membrane(GO:1990573)
1.4 4.3 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
1.4 11.3 GO:0007144 female meiosis I(GO:0007144)
1.4 9.5 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
1.3 38.9 GO:0040034 regulation of development, heterochronic(GO:0040034)
1.3 8.0 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
1.3 3.8 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
1.2 8.2 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
1.1 66.2 GO:0051290 protein heterotetramerization(GO:0051290)
1.1 10.9 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
1.0 38.5 GO:0006270 DNA replication initiation(GO:0006270)
1.0 3.0 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
0.9 32.5 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.9 26.1 GO:0008340 determination of adult lifespan(GO:0008340)
0.9 22.3 GO:0010544 negative regulation of platelet activation(GO:0010544)
0.8 4.2 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.8 24.2 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.8 5.6 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.8 11.0 GO:0006241 CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.7 3.7 GO:0060161 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195) histone H4-R3 methylation(GO:0043985) positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.7 11.0 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.7 10.5 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.7 6.9 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.6 10.7 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.6 5.4 GO:0007000 nucleolus organization(GO:0007000)
0.6 17.7 GO:0051310 metaphase plate congression(GO:0051310)
0.5 27.2 GO:0090307 mitotic spindle assembly(GO:0090307)
0.5 6.2 GO:0014029 neural crest formation(GO:0014029)
0.5 4.6 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.5 23.7 GO:0006284 base-excision repair(GO:0006284)
0.5 10.4 GO:0031297 replication fork processing(GO:0031297)
0.5 5.0 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.4 4.2 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.4 5.3 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.4 9.1 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.3 2.8 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.3 4.2 GO:0000012 single strand break repair(GO:0000012)
0.3 2.7 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.3 12.8 GO:0006910 phagocytosis, recognition(GO:0006910)
0.3 2.5 GO:0015074 DNA integration(GO:0015074)
0.3 3.2 GO:0035608 protein deglutamylation(GO:0035608)
0.3 1.9 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.3 1.0 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.2 23.2 GO:0007051 spindle organization(GO:0007051)
0.2 2.0 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
0.2 1.1 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.2 2.5 GO:0051026 chiasma assembly(GO:0051026)
0.2 3.1 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.2 0.8 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
0.2 4.5 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.2 2.1 GO:0034508 centromere complex assembly(GO:0034508)
0.2 15.4 GO:0006334 nucleosome assembly(GO:0006334)
0.2 1.8 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.2 1.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 2.0 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 1.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 3.6 GO:0042073 intraciliary transport(GO:0042073)
0.1 2.1 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 2.5 GO:0048148 behavioral response to cocaine(GO:0048148)
0.1 3.2 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 4.3 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.2 GO:2000371 phosphatidylserine exposure on apoptotic cell surface(GO:0070782) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.1 0.4 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 6.4 GO:0010212 response to ionizing radiation(GO:0010212)
0.1 2.7 GO:0097120 receptor localization to synapse(GO:0097120)
0.1 3.7 GO:0015914 phospholipid transport(GO:0015914)
0.1 3.9 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 5.7 GO:0000956 nuclear-transcribed mRNA catabolic process(GO:0000956)
0.0 1.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 3.4 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.7 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 1.7 GO:0043171 peptide catabolic process(GO:0043171)
0.0 1.3 GO:0019835 cytolysis(GO:0019835)
0.0 3.4 GO:0007286 spermatid development(GO:0007286)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.7 GO:0006506 GPI anchor biosynthetic process(GO:0006506)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.7 34.3 GO:0031262 Ndc80 complex(GO:0031262)
5.4 27.2 GO:0031523 Myb complex(GO:0031523)
3.5 10.4 GO:0035101 FACT complex(GO:0035101)
3.2 9.5 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
2.4 21.2 GO:0008278 cohesin complex(GO:0008278)
2.0 9.8 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
1.8 16.0 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
1.7 10.2 GO:0070531 BRCA1-A complex(GO:0070531)
1.5 17.7 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
1.3 6.4 GO:0070876 SOSS complex(GO:0070876)
1.2 10.7 GO:0030991 intraciliary transport particle A(GO:0030991)
1.2 8.1 GO:0005638 lamin filament(GO:0005638)
1.1 23.5 GO:0031616 spindle pole centrosome(GO:0031616)
1.1 11.1 GO:0031080 nuclear pore outer ring(GO:0031080)
1.0 5.0 GO:0033553 rDNA heterochromatin(GO:0033553)
1.0 6.9 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.9 15.8 GO:0001673 male germ cell nucleus(GO:0001673)
0.9 6.4 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.8 4.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.8 13.8 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.8 3.8 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.7 9.5 GO:0042555 MCM complex(GO:0042555)
0.6 20.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.5 15.2 GO:0051233 spindle midzone(GO:0051233)
0.5 57.1 GO:0005882 intermediate filament(GO:0005882)
0.5 5.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.5 3.4 GO:0032300 mismatch repair complex(GO:0032300)
0.4 3.7 GO:0034709 methylosome(GO:0034709)
0.4 47.8 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.4 15.1 GO:0000786 nucleosome(GO:0000786)
0.4 1.1 GO:0099631 postsynaptic endocytic zone cytoplasmic component(GO:0099631)
0.3 1.2 GO:0008537 proteasome activator complex(GO:0008537)
0.3 25.4 GO:0000922 spindle pole(GO:0000922)
0.3 13.4 GO:0000793 condensed chromosome(GO:0000793)
0.2 13.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 5.6 GO:0001891 phagocytic cup(GO:0001891)
0.1 14.7 GO:0043198 dendritic shaft(GO:0043198)
0.1 15.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 8.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 10.0 GO:0030315 T-tubule(GO:0030315)
0.1 0.8 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 0.5 GO:0070847 core mediator complex(GO:0070847)
0.1 7.7 GO:0005795 Golgi stack(GO:0005795)
0.1 2.7 GO:0060077 inhibitory synapse(GO:0060077)
0.1 3.2 GO:0072686 mitotic spindle(GO:0072686)
0.1 4.6 GO:0030286 dynein complex(GO:0030286)
0.1 2.0 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 3.1 GO:0015030 Cajal body(GO:0015030)
0.1 1.2 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 11.2 GO:0001650 fibrillar center(GO:0001650)
0.0 5.3 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 20.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 6.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 2.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 3.6 GO:0005930 axoneme(GO:0005930)
0.0 1.9 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 12.5 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.7 GO:0016235 aggresome(GO:0016235)
0.0 2.1 GO:0005643 nuclear pore(GO:0005643)
0.0 2.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.3 GO:0031010 ISWI-type complex(GO:0031010)
0.0 16.0 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 6.6 GO:0005925 focal adhesion(GO:0005925)
0.0 9.8 GO:0000785 chromatin(GO:0000785)
0.0 1.3 GO:0005814 centriole(GO:0005814)
0.0 1.1 GO:0045177 apical part of cell(GO:0045177)
0.0 14.8 GO:0005887 integral component of plasma membrane(GO:0005887)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
7.6 45.3 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
4.7 23.7 GO:0000405 bubble DNA binding(GO:0000405)
3.7 11.2 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
3.1 42.8 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
2.8 11.0 GO:0003883 CTP synthase activity(GO:0003883)
2.5 27.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
2.3 6.9 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
2.1 6.2 GO:0001042 RNA polymerase I core binding(GO:0001042)
1.9 9.5 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
1.9 13.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
1.9 5.6 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
1.8 7.2 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
1.7 17.2 GO:0036310 annealing helicase activity(GO:0036310)
1.5 16.0 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
1.2 7.2 GO:0035184 nucleosomal histone binding(GO:0031493) histone threonine kinase activity(GO:0035184)
1.1 3.4 GO:0032137 guanine/thymine mispair binding(GO:0032137) single guanine insertion binding(GO:0032142)
1.0 3.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
1.0 6.7 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.9 3.7 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.8 5.5 GO:0015616 DNA translocase activity(GO:0015616)
0.8 36.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.7 4.3 GO:0042731 PH domain binding(GO:0042731)
0.6 3.8 GO:0000150 recombinase activity(GO:0000150)
0.6 17.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.6 5.0 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.5 2.0 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.5 24.2 GO:0050699 WW domain binding(GO:0050699)
0.5 17.7 GO:0070840 dynein complex binding(GO:0070840)
0.5 2.5 GO:0030983 mismatched DNA binding(GO:0030983)
0.4 3.0 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.4 9.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.4 13.8 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.4 9.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.3 2.7 GO:0030274 LIM domain binding(GO:0030274)
0.3 8.1 GO:0008432 JUN kinase binding(GO:0008432)
0.3 9.5 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.3 14.8 GO:0003684 damaged DNA binding(GO:0003684)
0.3 13.8 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 20.0 GO:0005518 collagen binding(GO:0005518)
0.2 16.0 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 9.7 GO:0008378 galactosyltransferase activity(GO:0008378)
0.2 1.0 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 0.8 GO:0097108 hedgehog family protein binding(GO:0097108)
0.2 1.9 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.2 4.6 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 1.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 3.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 3.2 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 4.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 11.6 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.1 2.8 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.1 3.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 4.2 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 2.0 GO:0016208 AMP binding(GO:0016208)
0.1 1.8 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 1.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 2.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 14.2 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.1 0.5 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 1.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 10.6 GO:0042393 histone binding(GO:0042393)
0.1 1.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 2.2 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 1.1 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 2.7 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 8.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.7 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.2 GO:0038132 neuregulin binding(GO:0038132)
0.0 8.3 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.7 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 2.5 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 10.1 GO:0003682 chromatin binding(GO:0003682)
0.0 0.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 25.0 GO:0042802 identical protein binding(GO:0042802)
0.0 0.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 2.1 GO:0017137 Rab GTPase binding(GO:0017137)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 59.8 PID ATR PATHWAY ATR signaling pathway
1.0 13.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.8 33.8 PID AURORA A PATHWAY Aurora A signaling
0.5 16.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.4 47.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.4 30.9 PID E2F PATHWAY E2F transcription factor network
0.3 10.0 PID FANCONI PATHWAY Fanconi anemia pathway
0.3 10.4 ST GAQ PATHWAY G alpha q Pathway
0.3 11.2 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 8.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 2.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 4.3 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 6.7 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.1 2.7 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 5.0 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 9.5 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 15.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 4.3 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.1 PID ARF 3PATHWAY Arf1 pathway
0.0 0.7 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.0 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.5 PID LKB1 PATHWAY LKB1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 24.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
2.2 56.2 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
1.5 22.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
1.4 9.5 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
1.2 10.9 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
1.1 15.7 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
1.1 9.8 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.9 42.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.8 40.5 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.6 9.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.6 11.6 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.6 6.9 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.6 1.7 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.5 60.9 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.5 9.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.4 10.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.4 11.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.4 7.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.3 9.7 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.3 2.5 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.3 8.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.2 5.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.2 2.7 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.2 17.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 11.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.2 3.7 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.2 4.2 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.1 2.5 REACTOME MEIOSIS Genes involved in Meiosis
0.1 2.0 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 3.1 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 3.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 3.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 1.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 4.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 7.7 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 4.3 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 1.1 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 0.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.7 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.2 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6