ISMARA results: E2f1

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GSE58827: Dynamics of the Mouse Liver

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Results for E2f1

Z-value: 5.25

Motif logo

Transcription factors associated with E2f1

Gene Symbol	Gene ID	Gene Info
E2f1 Ensembl NCBI MGI UniProt	ENSMUSG00000027490.11	E2F transcription factor 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
E2f1	mm10_v2_chr2_-_154569845_154569892	0.95	2.2e-19	Click!

Activity profile of E2f1 motif

Sorted Z-values of E2f1 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr14_-_79301623 Show fit	64.65	ENSMUST00000022595.7	Rgcc Ensembl NCBI MGI UniProt Show fit	regulator of cell cycle
chr2_+_163054682 Show fit	40.66	ENSMUST00000018005.3	Mybl2 Ensembl NCBI MGI UniProt Show fit	myeloblastosis oncogene-like 2
chr12_-_76709997 Show fit	36.37	ENSMUST00000166101.1	Sptb Ensembl NCBI MGI UniProt Show fit	spectrin beta, erythrocytic
chr11_+_98907801 Show fit	35.84	ENSMUST00000092706.6	Cdc6 Ensembl NCBI MGI UniProt Show fit	cell division cycle 6
chr17_+_56303396 Show fit	35.63	ENSMUST00000113038.1	Uhrf1 Ensembl NCBI MGI UniProt Show fit	ubiquitin-like, containing PHD and RING finger domains, 1
chr4_-_46404224 Show fit	34.37	ENSMUST00000107764.2	Hemgn Ensembl NCBI MGI UniProt Show fit	hemogen
chr7_-_142578139 Show fit	34.24	ENSMUST00000136359.1	H19 Ensembl NCBI MGI UniProt Show fit	H19 fetal liver mRNA
chr7_-_142578093 Show fit	34.11	ENSMUST00000149974.1 ENSMUST00000152754.1	H19 Ensembl NCBI MGI UniProt Show fit	H19 fetal liver mRNA
chr2_-_28621932 Show fit	31.72	ENSMUST00000028156.7 ENSMUST00000164290.1	Gfi1b Ensembl NCBI MGI UniProt Show fit	growth factor independent 1B
chr11_-_69948145 Show fit	31.03	ENSMUST00000179298.1 ENSMUST00000018710.6 ENSMUST00000135437.1 ENSMUST00000141837.2 ENSMUST00000142500.1	Slc2a4 Ensembl NCBI MGI UniProt Show fit	solute carrier family 2 (facilitated glucose transporter), member 4
chr4_+_126556935 Show fit	30.46	ENSMUST00000048391.8	Clspn Ensembl NCBI MGI UniProt Show fit	claspin
chr17_+_56303321 Show fit	30.45	ENSMUST00000001258.8	Uhrf1 Ensembl NCBI MGI UniProt Show fit	ubiquitin-like, containing PHD and RING finger domains, 1
chr5_+_45669907 Show fit	29.93	ENSMUST00000117396.1	Ncapg Ensembl NCBI MGI UniProt Show fit	non-SMC condensin I complex, subunit G
chr5_+_76840597 Show fit	29.09	ENSMUST00000120639.2 ENSMUST00000163347.1 ENSMUST00000121851.1	C530008M17Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA C530008M17 gene
chr14_-_47276790 Show fit	27.23	ENSMUST00000111792.1 ENSMUST00000111791.1 ENSMUST00000111790.1	Wdhd1 Ensembl NCBI MGI UniProt Show fit	WD repeat and HMG-box DNA binding protein 1
chr16_-_18621366 Show fit	26.46	ENSMUST00000051160.2	Gp1bb Ensembl NCBI MGI UniProt Show fit	glycoprotein Ib, beta polypeptide
chr13_+_73467197 Show fit	26.25	ENSMUST00000022099.8	Lpcat1 Ensembl NCBI MGI UniProt Show fit	lysophosphatidylcholine acyltransferase 1
chr4_+_126556994 Show fit	24.70	ENSMUST00000147675.1	Clspn Ensembl NCBI MGI UniProt Show fit	claspin
chrX_-_52613936 Show fit	24.25	ENSMUST00000114857.1	Gpc3 Ensembl NCBI MGI UniProt Show fit	glypican 3
chr6_+_134929118 Show fit	23.90	ENSMUST00000185152.1 ENSMUST00000184504.1	RP23-45G16.5 Ensembl NCBI MGI UniProt Show fit	RP23-45G16.5
chrX_-_52613913 Show fit	23.57	ENSMUST00000069360.7	Gpc3 Ensembl NCBI MGI UniProt Show fit	glypican 3
chr12_+_69168808 Show fit	22.98	ENSMUST00000110621.1	Lrr1 Ensembl NCBI MGI UniProt Show fit	leucine rich repeat protein 1
chr6_+_134929089 Show fit	22.75	ENSMUST00000183867.1 ENSMUST00000184991.1 ENSMUST00000183905.1	RP23-45G16.5 Ensembl NCBI MGI UniProt Show fit	RP23-45G16.5
chr8_-_71723308 Show fit	22.69	ENSMUST00000125092.1	Fcho1 Ensembl NCBI MGI UniProt Show fit	FCH domain only 1
chr7_+_102441685 Show fit	22.60	ENSMUST00000033283.9	Rrm1 Ensembl NCBI MGI UniProt Show fit	ribonucleotide reductase M1
chrX_-_104671048 Show fit	22.06	ENSMUST00000042070.5	Zdhhc15 Ensembl NCBI MGI UniProt Show fit	zinc finger, DHHC domain containing 15
chr11_+_24080664 Show fit	22.04	ENSMUST00000118955.1	Bcl11a Ensembl NCBI MGI UniProt Show fit	B cell CLL/lymphoma 11A (zinc finger protein)
chr4_+_108579445 Show fit	22.01	ENSMUST00000102744.3	Orc1 Ensembl NCBI MGI UniProt Show fit	origin recognition complex, subunit 1
chrX_-_51205990 Show fit	21.90	ENSMUST00000114876.2	Mbnl3 Ensembl NCBI MGI UniProt Show fit	muscleblind-like 3 (Drosophila)
chr9_+_65890237 Show fit	21.71	ENSMUST00000045802.6	2810417H13Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 2810417H13 gene
chr12_+_24708241 Show fit	21.49	ENSMUST00000020980.5	Rrm2 Ensembl NCBI MGI UniProt Show fit	ribonucleotide reductase M2
chr7_+_13278778 Show fit	21.41	ENSMUST00000098814.4 ENSMUST00000146998.1 ENSMUST00000185145.1	Lig1 Ensembl NCBI MGI UniProt Show fit	ligase I, DNA, ATP-dependent
chr11_+_95010277 Show fit	21.32	ENSMUST00000124735.1	Samd14 Ensembl NCBI MGI UniProt Show fit	sterile alpha motif domain containing 14
chr7_+_67952817 Show fit	20.64	ENSMUST00000005671.8	Igf1r Ensembl NCBI MGI UniProt Show fit	insulin-like growth factor I receptor
chr12_+_116405397 Show fit	20.30	ENSMUST00000084828.3	Ncapg2 Ensembl NCBI MGI UniProt Show fit	non-SMC condensin II complex, subunit G2
chr1_-_191575534 Show fit	20.11	ENSMUST00000027933.5	Dtl Ensembl NCBI MGI UniProt Show fit	denticleless homolog (Drosophila)
chr13_-_100775844 Show fit	19.75	ENSMUST00000075550.3	Cenph Ensembl NCBI MGI UniProt Show fit	centromere protein H
chr16_-_15637277 Show fit	19.72	ENSMUST00000023353.3	Mcm4 Ensembl NCBI MGI UniProt Show fit	minichromosome maintenance deficient 4 homolog (S. cerevisiae)
chrX_-_111463149 Show fit	19.51	ENSMUST00000096348.3 ENSMUST00000113428.2	Rps6ka6 Ensembl NCBI MGI UniProt Show fit	ribosomal protein S6 kinase polypeptide 6
chr11_+_53519920 Show fit	19.32	ENSMUST00000147912.1	Sept8 Ensembl NCBI MGI UniProt Show fit	septin 8
chr13_-_47105790 Show fit	19.30	ENSMUST00000129352.1	Dek Ensembl NCBI MGI UniProt Show fit	DEK oncogene (DNA binding)
chr5_+_76657673 Show fit	19.25	ENSMUST00000128112.1	C530008M17Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA C530008M17 gene
chr5_+_106964319 Show fit	19.24	ENSMUST00000031221.5 ENSMUST00000117196.2 ENSMUST00000076467.6	Cdc7 Ensembl NCBI MGI UniProt Show fit	cell division cycle 7 (S. cerevisiae)
chr1_-_20820213 Show fit	18.66	ENSMUST00000053266.9	Mcm3 Ensembl NCBI MGI UniProt Show fit	minichromosome maintenance deficient 3 (S. cerevisiae)
chr17_-_56830916 Show fit	18.57	ENSMUST00000002444.7 ENSMUST00000086801.5	Rfx2 Ensembl NCBI MGI UniProt Show fit	regulatory factor X, 2 (influences HLA class II expression)
chrX_-_136215443 Show fit	18.46	ENSMUST00000113120.1 ENSMUST00000113118.1 ENSMUST00000058125.8	Bex1 Ensembl NCBI MGI UniProt Show fit	brain expressed gene 1
chr7_-_141443989 Show fit	18.25	ENSMUST00000026580.5	Lrdd Ensembl NCBI MGI UniProt Show fit	leucine-rich and death domain containing
chr1_-_190978954 Show fit	18.25	ENSMUST00000047409.6	Vash2 Ensembl NCBI MGI UniProt Show fit	vasohibin 2
chr5_-_138170992 Show fit	18.22	ENSMUST00000139983.1	Mcm7 Ensembl NCBI MGI UniProt Show fit	minichromosome maintenance deficient 7 (S. cerevisiae)
chr5_-_138171248 Show fit	17.94	ENSMUST00000153867.1	Mcm7 Ensembl NCBI MGI UniProt Show fit	minichromosome maintenance deficient 7 (S. cerevisiae)
chr11_+_58948890 Show fit	17.93	ENSMUST00000078267.3	Hist3h2ba Ensembl NCBI MGI UniProt Show fit	histone cluster 3, H2ba
chr10_-_19851459 Show fit	17.86	ENSMUST00000059805.4	Slc35d3 Ensembl NCBI MGI UniProt Show fit	solute carrier family 35, member D3
chr9_-_61946768 Show fit	17.75	ENSMUST00000034815.7	Kif23 Ensembl NCBI MGI UniProt Show fit	kinesin family member 23
chr5_-_138171216 Show fit	17.73	ENSMUST00000147920.1	Mcm7 Ensembl NCBI MGI UniProt Show fit	minichromosome maintenance deficient 7 (S. cerevisiae)
chr16_+_93883895 Show fit	17.62	ENSMUST00000023666.4 ENSMUST00000117099.1 ENSMUST00000142316.1	Chaf1b Ensembl NCBI MGI UniProt Show fit	chromatin assembly factor 1, subunit B (p60)
chr9_+_13246982 Show fit	17.18	ENSMUST00000110583.2 ENSMUST00000169961.1	Ccdc82 Ensembl NCBI MGI UniProt Show fit	coiled-coil domain containing 82
chr17_+_35841668 Show fit	17.17	ENSMUST00000174124.1	Mdc1 Ensembl NCBI MGI UniProt Show fit	mediator of DNA damage checkpoint 1
chr16_+_37011758 Show fit	17.13	ENSMUST00000071452.5 ENSMUST00000054034.6	Polq Ensembl NCBI MGI UniProt Show fit	polymerase (DNA directed), theta
chr13_-_47106176 Show fit	16.91	ENSMUST00000021807.6 ENSMUST00000135278.1	Dek Ensembl NCBI MGI UniProt Show fit	DEK oncogene (DNA binding)
chr4_+_115000174 Show fit	16.83	ENSMUST00000129957.1	Stil Ensembl NCBI MGI UniProt Show fit	Scl/Tal1 interrupting locus
chrX_+_136138996 Show fit	16.80	ENSMUST00000116527.1	Bex4 Ensembl NCBI MGI UniProt Show fit	brain expressed gene 4
chr5_+_123749696 Show fit	16.69	ENSMUST00000031366.7	Kntc1 Ensembl NCBI MGI UniProt Show fit	kinetochore associated 1
chr11_+_95009852 Show fit	16.67	ENSMUST00000055947.3	Samd14 Ensembl NCBI MGI UniProt Show fit	sterile alpha motif domain containing 14
chr4_+_115000156 Show fit	16.36	ENSMUST00000030490.6	Stil Ensembl NCBI MGI UniProt Show fit	Scl/Tal1 interrupting locus
chr4_+_52439235 Show fit	16.07	ENSMUST00000117280.1 ENSMUST00000102915.3 ENSMUST00000142227.1	Smc2 Ensembl NCBI MGI UniProt Show fit	structural maintenance of chromosomes 2
chr13_+_54701457 Show fit	15.97	ENSMUST00000037145.7	Cdhr2 Ensembl NCBI MGI UniProt Show fit	cadherin-related family member 2
chr6_+_113531675 Show fit	15.95	ENSMUST00000036340.5 ENSMUST00000101051.2	Fancd2 Ensembl NCBI MGI UniProt Show fit	Fanconi anemia, complementation group D2
chr6_-_126939524 Show fit	15.57	ENSMUST00000144954.1 ENSMUST00000112221.1 ENSMUST00000112220.1	Rad51ap1 Ensembl NCBI MGI UniProt Show fit	RAD51 associated protein 1
chr8_+_71406003 Show fit	14.96	ENSMUST00000119976.1 ENSMUST00000120725.1	Ankle1 Ensembl NCBI MGI UniProt Show fit	ankyrin repeat and LEM domain containing 1
chr15_-_55090422 Show fit	14.94	ENSMUST00000110231.1 ENSMUST00000023059.6	Dscc1 Ensembl NCBI MGI UniProt Show fit	defective in sister chromatid cohesion 1 homolog (S. cerevisiae)
chr8_+_3665747 Show fit	14.94	ENSMUST00000014118.2	1810033B17Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 1810033B17 gene
chr9_+_70679016 Show fit	14.93	ENSMUST00000144537.1	Adam10 Ensembl NCBI MGI UniProt Show fit	a disintegrin and metallopeptidase domain 10
chrX_+_71555918 Show fit	14.87	ENSMUST00000072699.6 ENSMUST00000114582.2 ENSMUST00000015361.4 ENSMUST00000088874.3	Hmgb3 Ensembl NCBI MGI UniProt Show fit	high mobility group box 3
chr19_-_9899450 Show fit	14.84	ENSMUST00000025562.7	Incenp Ensembl NCBI MGI UniProt Show fit	inner centromere protein
chr3_-_54915867 Show fit	14.73	ENSMUST00000070342.3	Sertm1 Ensembl NCBI MGI UniProt Show fit	serine rich and transmembrane domain containing 1
chr5_+_115845229 Show fit	14.43	ENSMUST00000137952.1 ENSMUST00000148245.1	Cit Ensembl NCBI MGI UniProt Show fit	citron
chr16_-_91688703 Show fit	14.39	ENSMUST00000138560.1 ENSMUST00000023682.4 ENSMUST00000117159.1 ENSMUST00000114031.1	Donson Ensembl NCBI MGI UniProt Show fit	downstream neighbor of SON
chr11_+_53519871 Show fit	14.38	ENSMUST00000120878.2	Sept8 Ensembl NCBI MGI UniProt Show fit	septin 8
chr11_+_62248977 Show fit	14.02	ENSMUST00000018644.2	Adora2b Ensembl NCBI MGI UniProt Show fit	adenosine A2b receptor
chr6_-_122801639 Show fit	13.98	ENSMUST00000165884.1	Slc2a3 Ensembl NCBI MGI UniProt Show fit	solute carrier family 2 (facilitated glucose transporter), member 3
chr2_+_131491764 Show fit	13.84	ENSMUST00000028806.5 ENSMUST00000110179.2 ENSMUST00000110189.2 ENSMUST00000110182.2 ENSMUST00000110183.2 ENSMUST00000110186.2 ENSMUST00000110188.1	Smox Ensembl NCBI MGI UniProt Show fit	spermine oxidase
chr17_+_25016343 Show fit	13.61	ENSMUST00000024983.5	Ift140 Ensembl NCBI MGI UniProt Show fit	intraflagellar transport 140
chr2_+_131491958 Show fit	13.48	ENSMUST00000110181.1 ENSMUST00000110180.1	Smox Ensembl NCBI MGI UniProt Show fit	spermine oxidase
chr11_+_87755567 Show fit	13.28	ENSMUST00000123700.1	A430104N18Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA A430104N18 gene
chr3_+_114030532 Show fit	13.17	ENSMUST00000123619.1 ENSMUST00000092155.5	Col11a1 Ensembl NCBI MGI UniProt Show fit	collagen, type XI, alpha 1
chr15_+_73723131 Show fit	13.13	ENSMUST00000165541.1 ENSMUST00000167582.1	Ptp4a3 Ensembl NCBI MGI UniProt Show fit	protein tyrosine phosphatase 4a3
chr10_+_3973086 Show fit	12.86	ENSMUST00000117291.1 ENSMUST00000120585.1 ENSMUST00000043735.7	Mthfd1l Ensembl NCBI MGI UniProt Show fit	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr12_-_84698769 Show fit	12.79	ENSMUST00000095550.2	Syndig1l Ensembl NCBI MGI UniProt Show fit	synapse differentiation inducing 1 like
chr3_+_40800013 Show fit	12.71	ENSMUST00000026858.5 ENSMUST00000170825.1	Plk4 Ensembl NCBI MGI UniProt Show fit	polo-like kinase 4
chr4_-_133968611 Show fit	12.69	ENSMUST00000102552.1	Hmgn2 Ensembl NCBI MGI UniProt Show fit	high mobility group nucleosomal binding domain 2
chr1_-_133801031 Show fit	12.62	ENSMUST00000143567.1	Atp2b4 Ensembl NCBI MGI UniProt Show fit	ATPase, Ca++ transporting, plasma membrane 4
chr12_+_24708984 Show fit	12.56	ENSMUST00000154588.1	Rrm2 Ensembl NCBI MGI UniProt Show fit	ribonucleotide reductase M2
chrX_-_111463103 Show fit	12.56	ENSMUST00000137712.2	Rps6ka6 Ensembl NCBI MGI UniProt Show fit	ribosomal protein S6 kinase polypeptide 6
chr19_-_10203880 Show fit	12.54	ENSMUST00000142241.1 ENSMUST00000116542.2 ENSMUST00000025651.5 ENSMUST00000156291.1	Fen1 Ensembl NCBI MGI UniProt Show fit	flap structure specific endonuclease 1
chr18_+_56707725 Show fit	12.51	ENSMUST00000025486.8	Lmnb1 Ensembl NCBI MGI UniProt Show fit	lamin B1
chr1_+_74506044 Show fit	12.41	ENSMUST00000087215.5	Rqcd1 Ensembl NCBI MGI UniProt Show fit	rcd1 (required for cell differentiation) homolog 1 (S. pombe)
chr15_-_58135047 Show fit	12.37	ENSMUST00000038194.3	Atad2 Ensembl NCBI MGI UniProt Show fit	ATPase family, AAA domain containing 2
chrX_+_170009659 Show fit	12.34	ENSMUST00000179760.1	Gm21887 Ensembl NCBI MGI UniProt Show fit	predicted gene, 21887
chr16_-_18811615 Show fit	12.23	ENSMUST00000096990.3	Cdc45 Ensembl NCBI MGI UniProt Show fit	cell division cycle 45
chr17_-_25944932 Show fit	12.23	ENSMUST00000085027.3	Nhlrc4 Ensembl NCBI MGI UniProt Show fit	NHL repeat containing 4
chr6_+_4755327 Show fit	12.19	ENSMUST00000176551.1	Peg10 Ensembl NCBI MGI UniProt Show fit	paternally expressed 10
chr2_-_160912292 Show fit	12.04	ENSMUST00000109454.1 ENSMUST00000057169.4	Emilin3 Ensembl NCBI MGI UniProt Show fit	elastin microfibril interfacer 3
chr5_+_33820695 Show fit	12.02	ENSMUST00000075812.4 ENSMUST00000114397.2 ENSMUST00000155880.1	Whsc1 Ensembl NCBI MGI UniProt Show fit	Wolf-Hirschhorn syndrome candidate 1 (human)
chr8_-_124434323 Show fit	11.91	ENSMUST00000140012.1	Pgbd5 Ensembl NCBI MGI UniProt Show fit	piggyBac transposable element derived 5
chrX_-_139871637 Show fit	11.86	ENSMUST00000033811.7 ENSMUST00000087401.5	Morc4 Ensembl NCBI MGI UniProt Show fit	microrchidia 4
chr4_-_43046196 Show fit	11.83	ENSMUST00000036462.5	Fam214b Ensembl NCBI MGI UniProt Show fit	family with sequence similarity 214, member B
chr7_+_100493337 Show fit	11.72	ENSMUST00000126534.1	Ucp2 Ensembl NCBI MGI UniProt Show fit	uncoupling protein 2 (mitochondrial, proton carrier)
chr13_-_55329723 Show fit	11.65	ENSMUST00000021941.7	Mxd3 Ensembl NCBI MGI UniProt Show fit	Max dimerization protein 3
chr10_-_21160925 Show fit	11.65	ENSMUST00000020158.6	Myb Ensembl NCBI MGI UniProt Show fit	myeloblastosis oncogene
chr8_+_94179089 Show fit	11.59	ENSMUST00000034215.6	Mt1 Ensembl NCBI MGI UniProt Show fit	metallothionein 1
chrX_-_51205773 Show fit	11.59	ENSMUST00000114875.1	Mbnl3 Ensembl NCBI MGI UniProt Show fit	muscleblind-like 3 (Drosophila)
chr15_+_80091320 Show fit	11.56	ENSMUST00000009728.6 ENSMUST00000009727.5	Syngr1 Ensembl NCBI MGI UniProt Show fit	synaptogyrin 1
chrX_+_35888808 Show fit	11.55	ENSMUST00000033419.6	Dock11 Ensembl NCBI MGI UniProt Show fit	dedicator of cytokinesis 11
chr3_+_40800054 Show fit	11.52	ENSMUST00000168287.1	Plk4 Ensembl NCBI MGI UniProt Show fit	polo-like kinase 4
chr18_-_67641329 Show fit	11.41	ENSMUST00000097542.2	Cep76 Ensembl NCBI MGI UniProt Show fit	centrosomal protein 76
chr11_+_53519725 Show fit	11.32	ENSMUST00000108987.1 ENSMUST00000121334.1 ENSMUST00000117061.1	Sept8 Ensembl NCBI MGI UniProt Show fit	septin 8
chr14_-_73325773 Show fit	11.28	ENSMUST00000022701.6	Rb1 Ensembl NCBI MGI UniProt Show fit	retinoblastoma 1
chr5_-_67847360 Show fit	11.27	ENSMUST00000072971.6	Atp8a1 Ensembl NCBI MGI UniProt Show fit	ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr2_+_52072823 Show fit	11.26	ENSMUST00000112693.2 ENSMUST00000069794.5	Rif1 Ensembl NCBI MGI UniProt Show fit	Rap1 interacting factor 1 homolog (yeast)
chr19_+_47178820 Show fit	11.24	ENSMUST00000111808.3	Neurl1a Ensembl NCBI MGI UniProt Show fit	neuralized homolog 1A (Drosophila)
chr4_-_133967893 Show fit	11.17	ENSMUST00000100472.3 ENSMUST00000136327.1	Hmgn2 Ensembl NCBI MGI UniProt Show fit	high mobility group nucleosomal binding domain 2
chr4_-_152477433 Show fit	11.17	ENSMUST00000159186.1 ENSMUST00000162017.1 ENSMUST00000030768.2	Kcnab2 Ensembl NCBI MGI UniProt Show fit	potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr7_+_45554893 Show fit	11.16	ENSMUST00000107752.3	Hsd17b14 Ensembl NCBI MGI UniProt Show fit	hydroxysteroid (17-beta) dehydrogenase 14
chr4_+_24496434 Show fit	10.94	ENSMUST00000108222.2 ENSMUST00000138567.2 ENSMUST00000050446.6	Mms22l Ensembl NCBI MGI UniProt Show fit	MMS22-like, DNA repair protein
chr9_-_58741543 Show fit	10.93	ENSMUST00000098674.4	2410076I21Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 2410076I21 gene
chr12_+_109743787 Show fit	10.91	ENSMUST00000183068.1	Mirg Ensembl NCBI MGI UniProt Show fit	miRNA containing gene
chr9_-_21291124 Show fit	10.88	ENSMUST00000086374.6	Cdkn2d Ensembl NCBI MGI UniProt Show fit	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr11_-_11808923 Show fit	10.84	ENSMUST00000109664.1 ENSMUST00000150714.1 ENSMUST00000047689.4 ENSMUST00000171938.1 ENSMUST00000171080.1	Fignl1 Ensembl NCBI MGI UniProt Show fit	fidgetin-like 1
chr18_-_58209926 Show fit	10.81	ENSMUST00000025497.6	Fbn2 Ensembl NCBI MGI UniProt Show fit	fibrillin 2
chr10_+_128232065 Show fit	10.72	ENSMUST00000055539.4 ENSMUST00000105244.1 ENSMUST00000105243.2 ENSMUST00000125289.1 ENSMUST00000105242.1	Timeless Ensembl NCBI MGI UniProt Show fit	timeless circadian clock 1
chrX_-_8145679 Show fit	10.59	ENSMUST00000115619.1 ENSMUST00000115617.3 ENSMUST00000040010.3	Rbm3 Ensembl NCBI MGI UniProt Show fit	RNA binding motif protein 3
chr17_-_29888570 Show fit	10.48	ENSMUST00000171691.1	Mdga1 Ensembl NCBI MGI UniProt Show fit	MAM domain containing glycosylphosphatidylinositol anchor 1
chr7_-_67803489 Show fit	10.44	ENSMUST00000181235.1	4833412C05Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 4833412C05 gene
chr11_+_80089385 Show fit	10.44	ENSMUST00000108239.1 ENSMUST00000017694.5	Atad5 Ensembl NCBI MGI UniProt Show fit	ATPase family, AAA domain containing 5
chr7_+_99535439 Show fit	10.38	ENSMUST00000098266.2 ENSMUST00000179755.1	Arrb1 Ensembl NCBI MGI UniProt Show fit	arrestin, beta 1
chr10_-_91082704 Show fit	10.38	ENSMUST00000162618.1 ENSMUST00000020157.6 ENSMUST00000160788.1	Apaf1 Ensembl NCBI MGI UniProt Show fit	apoptotic peptidase activating factor 1
chr14_+_32321987 Show fit	10.30	ENSMUST00000022480.7	Ogdhl Ensembl NCBI MGI UniProt Show fit	oxoglutarate dehydrogenase-like
chr10_-_120476469 Show fit	10.29	ENSMUST00000072777.7 ENSMUST00000159699.1	Hmga2 Ensembl NCBI MGI UniProt Show fit	high mobility group AT-hook 2
chr17_+_28769307 Show fit	10.26	ENSMUST00000004986.6	Mapk13 Ensembl NCBI MGI UniProt Show fit	mitogen-activated protein kinase 13
chr4_+_135152496 Show fit	10.26	ENSMUST00000119564.1	Runx3 Ensembl NCBI MGI UniProt Show fit	runt related transcription factor 3
chr8_-_122551316 Show fit	10.20	ENSMUST00000067252.7	Piezo1 Ensembl NCBI MGI UniProt Show fit	piezo-type mechanosensitive ion channel component 1
chr16_+_17646564 Show fit	10.18	ENSMUST00000182117.1 ENSMUST00000182671.1 ENSMUST00000182344.1	Ccdc74a Ensembl NCBI MGI UniProt Show fit	coiled-coil domain containing 74A
chr2_+_29869484 Show fit	10.09	ENSMUST00000047521.6 ENSMUST00000134152.1	Cercam Ensembl NCBI MGI UniProt Show fit	cerebral endothelial cell adhesion molecule
chr18_-_80363622 Show fit	10.02	ENSMUST00000184366.1	Kcng2 Ensembl NCBI MGI UniProt Show fit	potassium voltage-gated channel, subfamily G, member 2
chr13_+_21722057 Show fit	10.02	ENSMUST00000110476.3	Hist1h2bm Ensembl NCBI MGI UniProt Show fit	histone cluster 1, H2bm
chr8_+_75109528 Show fit	9.97	ENSMUST00000164309.1	Mcm5 Ensembl NCBI MGI UniProt Show fit	minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)
chr17_+_35841491 Show fit	9.95	ENSMUST00000082337.6	Mdc1 Ensembl NCBI MGI UniProt Show fit	mediator of DNA damage checkpoint 1
chr13_-_107022027 Show fit	9.85	ENSMUST00000117539.1 ENSMUST00000122233.1 ENSMUST00000022204.9 ENSMUST00000159772.1	Kif2a Ensembl NCBI MGI UniProt Show fit	kinesin family member 2A
chr17_+_25016068 Show fit	9.84	ENSMUST00000137386.1	Ift140 Ensembl NCBI MGI UniProt Show fit	intraflagellar transport 140
chr5_-_44101668 Show fit	9.82	ENSMUST00000087441.4 ENSMUST00000074113.6	Prom1 Ensembl NCBI MGI UniProt Show fit	prominin 1
chr1_-_190979280 Show fit	9.76	ENSMUST00000166139.1	Vash2 Ensembl NCBI MGI UniProt Show fit	vasohibin 2
chr17_-_71526819 Show fit	9.73	ENSMUST00000024851.9	Ndc80 Ensembl NCBI MGI UniProt Show fit	NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr2_-_66124994 Show fit	9.71	ENSMUST00000028378.3	Galnt3 Ensembl NCBI MGI UniProt Show fit	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3
chr7_+_97453204 Show fit	9.69	ENSMUST00000050732.7 ENSMUST00000121987.1	Kctd14 Ensembl NCBI MGI UniProt Show fit	potassium channel tetramerisation domain containing 14
chr14_+_99298652 Show fit	9.67	ENSMUST00000005279.6	Klf5 Ensembl NCBI MGI UniProt Show fit	Kruppel-like factor 5
chr8_-_78508876 Show fit	9.65	ENSMUST00000049245.7	Rbmxl1 Ensembl NCBI MGI UniProt Show fit	RNA binding motif protein, X linked-like-1
chr16_+_17646464 Show fit	9.60	ENSMUST00000056962.4	Ccdc74a Ensembl NCBI MGI UniProt Show fit	coiled-coil domain containing 74A
chr4_+_131873608 Show fit	9.57	ENSMUST00000053819.3	Srsf4 Ensembl NCBI MGI UniProt Show fit	serine/arginine-rich splicing factor 4
chr2_+_119618717 Show fit	9.51	ENSMUST00000028771.7	Nusap1 Ensembl NCBI MGI UniProt Show fit	nucleolar and spindle associated protein 1
chr17_+_56304313 Show fit	9.43	ENSMUST00000113035.1 ENSMUST00000113039.2 ENSMUST00000142387.1	Uhrf1 Ensembl NCBI MGI UniProt Show fit	ubiquitin-like, containing PHD and RING finger domains, 1
chr8_-_53638945 Show fit	9.39	ENSMUST00000047768.4	Neil3 Ensembl NCBI MGI UniProt Show fit	nei like 3 (E. coli)
chr3_+_65666223 Show fit	9.38	ENSMUST00000099075.2 ENSMUST00000107848.1 ENSMUST00000161794.1	Lekr1 Ensembl NCBI MGI UniProt Show fit	leucine, glutamate and lysine rich 1
chrX_-_47892502 Show fit	9.33	ENSMUST00000077569.4 ENSMUST00000101616.2 ENSMUST00000088973.4	Smarca1 Ensembl NCBI MGI UniProt Show fit	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr12_-_109068173 Show fit	9.29	ENSMUST00000073156.7	Begain Ensembl NCBI MGI UniProt Show fit	brain-enriched guanylate kinase-associated
chr4_+_13743424 Show fit	9.28	ENSMUST00000006761.3	Runx1t1 Ensembl NCBI MGI UniProt Show fit	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_+_154613297 Show fit	9.28	ENSMUST00000081926.6 ENSMUST00000109702.1	Zfp341 Ensembl NCBI MGI UniProt Show fit	zinc finger protein 341
chr5_-_67847400 Show fit	9.26	ENSMUST00000113652.1 ENSMUST00000113651.1 ENSMUST00000037380.8	Atp8a1 Ensembl NCBI MGI UniProt Show fit	ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr4_-_133967235 Show fit	9.24	ENSMUST00000123234.1	Hmgn2 Ensembl NCBI MGI UniProt Show fit	high mobility group nucleosomal binding domain 2
chr10_-_80433615 Show fit	9.21	ENSMUST00000105346.3 ENSMUST00000020377.6 ENSMUST00000105340.1 ENSMUST00000020379.6 ENSMUST00000105344.1 ENSMUST00000105342.1 ENSMUST00000105345.3 ENSMUST00000105343.1	Tcf3 Ensembl NCBI MGI UniProt Show fit	transcription factor 3
chr4_-_116123618 Show fit	9.21	ENSMUST00000102704.3 ENSMUST00000102705.3	Rad54l Ensembl NCBI MGI UniProt Show fit	RAD54 like (S. cerevisiae)
chr10_+_128015157 Show fit	9.17	ENSMUST00000178041.1 ENSMUST00000026461.7	Prim1 Ensembl NCBI MGI UniProt Show fit	DNA primase, p49 subunit
chr4_-_117929466 Show fit	9.17	ENSMUST00000097913.2	Artn Ensembl NCBI MGI UniProt Show fit	artemin
chr7_-_83884289 Show fit	9.07	ENSMUST00000094216.3	Mesdc1 Ensembl NCBI MGI UniProt Show fit	mesoderm development candidate 1
chr10_-_81524225 Show fit	9.02	ENSMUST00000043709.7	Gna15 Ensembl NCBI MGI UniProt Show fit	guanine nucleotide binding protein, alpha 15
chr14_-_67715585 Show fit	9.02	ENSMUST00000163100.1 ENSMUST00000132705.1 ENSMUST00000124045.1	Cdca2 Ensembl NCBI MGI UniProt Show fit	cell division cycle associated 2
chr7_+_45215753 Show fit	9.00	ENSMUST00000033060.6 ENSMUST00000155313.1 ENSMUST00000107801.1	Tead2 Ensembl NCBI MGI UniProt Show fit	TEA domain family member 2
chr10_+_100015817 Show fit	8.95	ENSMUST00000130190.1 ENSMUST00000020129.7	Kitl Ensembl NCBI MGI UniProt Show fit	kit ligand
chr13_+_91461050 Show fit	8.94	ENSMUST00000004094.8 ENSMUST00000042122.8	Ssbp2 Ensembl NCBI MGI UniProt Show fit	single-stranded DNA binding protein 2
chr13_-_51793650 Show fit	8.90	ENSMUST00000110040.2 ENSMUST00000021900.7	Sema4d Ensembl NCBI MGI UniProt Show fit	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr9_-_36726374 Show fit	8.90	ENSMUST00000172702.2 ENSMUST00000172742.1 ENSMUST00000034625.5	Chek1 Ensembl NCBI MGI UniProt Show fit	checkpoint kinase 1
chr3_+_68869563 Show fit	8.87	ENSMUST00000054551.2	1110032F04Rik Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 1110032F04 gene
chr4_+_11191726 Show fit	8.85	ENSMUST00000029866.9 ENSMUST00000108324.3	Ccne2 Ensembl NCBI MGI UniProt Show fit	cyclin E2
chr7_-_38107490 Show fit	8.84	ENSMUST00000108023.3	Ccne1 Ensembl NCBI MGI UniProt Show fit	cyclin E1
chr14_+_31134853 Show fit	8.80	ENSMUST00000090212.4	Nt5dc2 Ensembl NCBI MGI UniProt Show fit	5'-nucleotidase domain containing 2
chr10_-_128704978 Show fit	8.80	ENSMUST00000026416.7 ENSMUST00000026415.7	Cdk2 Ensembl NCBI MGI UniProt Show fit	cyclin-dependent kinase 2
chr6_-_87590701 Show fit	8.78	ENSMUST00000050887.7	Prokr1 Ensembl NCBI MGI UniProt Show fit	prokineticin receptor 1
chr2_-_151009364 Show fit	8.77	ENSMUST00000109896.1	Ninl Ensembl NCBI MGI UniProt Show fit	ninein-like
chr11_-_34833631 Show fit	8.72	ENSMUST00000093191.2	Spdl1 Ensembl NCBI MGI UniProt Show fit	spindle apparatus coiled-coil protein 1
chrX_+_37048807 Show fit	8.71	ENSMUST00000060057.1	Sowahd Ensembl NCBI MGI UniProt Show fit	sosondowah ankyrin repeat domain family member D
chr18_-_52529692 Show fit	8.70	ENSMUST00000025409.7	Lox Ensembl NCBI MGI UniProt Show fit	lysyl oxidase
chr3_+_28781305 Show fit	8.65	ENSMUST00000060500.7	Eif5a2 Ensembl NCBI MGI UniProt Show fit	eukaryotic translation initiation factor 5A2
chr12_+_117843489 Show fit	8.65	ENSMUST00000021592.9	Cdca7l Ensembl NCBI MGI UniProt Show fit	cell division cycle associated 7 like
chr8_+_120488416 Show fit	8.63	ENSMUST00000034279.9	Gse1 Ensembl NCBI MGI UniProt Show fit	genetic suppressor element 1
chr1_+_191063001 Show fit	8.61	ENSMUST00000076952.5 ENSMUST00000139340.1 ENSMUST00000078259.6	Nsl1 Ensembl NCBI MGI UniProt Show fit	NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)
chr9_-_44344159 Show fit	8.61	ENSMUST00000077353.7	Hmbs Ensembl NCBI MGI UniProt Show fit	hydroxymethylbilane synthase
chr13_-_23551648 Show fit	8.60	ENSMUST00000102971.1	Hist1h4f Ensembl NCBI MGI UniProt Show fit	histone cluster 1, H4f
chr19_-_5894100 Show fit	8.56	ENSMUST00000055911.4	Tigd3 Ensembl NCBI MGI UniProt Show fit	tigger transposable element derived 3
chr16_-_23127702 Show fit	8.48	ENSMUST00000115338.1 ENSMUST00000115337.1 ENSMUST00000023598.8	Rfc4 Ensembl NCBI MGI UniProt Show fit	replication factor C (activator 1) 4
chr17_-_35516780 Show fit	8.38	ENSMUST00000160885.1 ENSMUST00000159009.1 ENSMUST00000161012.1	Tcf19 Ensembl NCBI MGI UniProt Show fit	transcription factor 19
chrY_+_90784738 Show fit	8.37	ENSMUST00000179483.1	Erdr1 Ensembl NCBI MGI UniProt Show fit	erythroid differentiation regulator 1

Network of associatons between targets according to the STRING database.

First level regulatory network of E2f1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
21.5	64.6	GO:0003330	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
9.2	92.2	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
8.7	43.3	GO:0072138	mesenchymal cell proliferation involved in ureteric bud development(GO:0072138)
8.0	31.9	GO:1903944	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
6.8	27.2	GO:0070829	heterochromatin maintenance(GO:0070829)
6.8	47.5	GO:2001032	regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
6.3	37.8	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
6.0	17.9	GO:0090481	pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
5.9	17.8	GO:0044837	assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
5.7	85.9	GO:0010216	maintenance of DNA methylation(GO:0010216)
5.6	16.9	GO:0097021	lymphocyte migration into lymphoid organs(GO:0097021)
5.5	22.0	GO:1904800	regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800)
5.5	38.5	GO:0098535	de novo centriole assembly(GO:0098535)
5.5	27.3	GO:0036151	phosphatidylcholine acyl-chain remodeling(GO:0036151)
5.4	70.8	GO:2000653	regulation of genetic imprinting(GO:2000653)
5.2	15.7	GO:1904980	regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
5.0	55.2	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
5.0	20.0	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
4.9	24.6	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
4.9	34.0	GO:0033567	DNA replication, Okazaki fragment processing(GO:0033567)
4.8	38.6	GO:0051572	negative regulation of histone H3-K4 methylation(GO:0051572)
4.8	14.3	GO:0099547	regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254)
4.5	22.7	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
4.5	13.6	GO:0032877	positive regulation of DNA endoreduplication(GO:0032877)
4.4	22.2	GO:0042117	monocyte activation(GO:0042117)
4.4	22.0	GO:0070318	positive regulation of G0 to G1 transition(GO:0070318)
4.3	98.3	GO:0006270	DNA replication initiation(GO:0006270)
4.2	12.6	GO:0045763	regulation of arginine metabolic process(GO:0000821) negative regulation of nitric oxide mediated signal transduction(GO:0010751) negative regulation of cellular amino acid metabolic process(GO:0045763)
4.2	12.5	GO:0031662	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
3.9	27.3	GO:0046208	spermine catabolic process(GO:0046208)
3.8	34.2	GO:1900262	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
3.7	14.6	GO:0090095	canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330) lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
3.6	3.6	GO:0046832	negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
3.6	10.8	GO:0071694	protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
3.6	10.7	GO:1904975	response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
3.6	10.7	GO:0051311	meiotic metaphase plate congression(GO:0051311)
3.6	64.1	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
3.5	53.0	GO:0007076	mitotic chromosome condensation(GO:0007076)
3.3	6.6	GO:0031938	regulation of chromatin silencing at telomere(GO:0031938)
3.3	9.8	GO:0072139	glomerular parietal epithelial cell differentiation(GO:0072139)
3.2	19.5	GO:0042891	antibiotic transport(GO:0042891)
3.2	16.1	GO:0045950	negative regulation of mitotic recombination(GO:0045950)
3.2	16.0	GO:1904970	brush border assembly(GO:1904970)
3.1	18.5	GO:0042699	follicle-stimulating hormone signaling pathway(GO:0042699)
3.0	12.1	GO:0007066	female meiosis sister chromatid cohesion(GO:0007066)
2.9	49.7	GO:0046599	regulation of centriole replication(GO:0046599)
2.9	14.4	GO:0035989	tendon development(GO:0035989)
2.8	14.0	GO:0070837	dehydroascorbic acid transport(GO:0070837)
2.7	40.2	GO:2000381	negative regulation of mesoderm development(GO:2000381)
2.6	2.6	GO:0051542	elastin biosynthetic process(GO:0051542)
2.6	5.2	GO:0015675	nickel cation transport(GO:0015675)
2.6	20.5	GO:0061091	regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
2.6	69.3	GO:0010569	regulation of double-strand break repair via homologous recombination(GO:0010569)
2.6	7.7	GO:0072278	metanephric comma-shaped body morphogenesis(GO:0072278) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
2.6	10.2	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
2.4	7.2	GO:0051316	attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316)
2.3	14.0	GO:0031284	positive regulation of chronic inflammatory response(GO:0002678) positive regulation of guanylate cyclase activity(GO:0031284)
2.3	2.3	GO:0090172	microtubule cytoskeleton organization involved in homologous chromosome segregation(GO:0090172)
2.3	20.3	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
2.2	6.6	GO:0071603	endothelial cell-cell adhesion(GO:0071603)
2.2	4.4	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
2.2	4.4	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
2.1	12.9	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
2.1	6.4	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
2.1	46.8	GO:0030261	chromosome condensation(GO:0030261)
2.1	12.7	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
2.1	6.3	GO:0045004	DNA replication proofreading(GO:0045004)
2.1	8.3	GO:0032417	positive regulation of sodium:proton antiporter activity(GO:0032417)
2.0	2.0	GO:0000019	regulation of mitotic recombination(GO:0000019)
2.0	8.1	GO:0048298	positive regulation of isotype switching to IgA isotypes(GO:0048298)
2.0	10.0	GO:1903527	positive regulation of membrane tubulation(GO:1903527)
1.9	7.7	GO:1900738	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
1.9	3.8	GO:1902263	apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
1.9	5.7	GO:0071707	immunoglobulin heavy chain V-D-J recombination(GO:0071707)
1.9	17.0	GO:0048251	elastic fiber assembly(GO:0048251)
1.9	5.7	GO:0014012	peripheral nervous system axon regeneration(GO:0014012)
1.9	5.6	GO:0061743	motor learning(GO:0061743)
1.9	37.1	GO:0031297	replication fork processing(GO:0031297)
1.8	1.8	GO:2000016	negative regulation of determination of dorsal identity(GO:2000016)
1.8	5.4	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
1.8	5.4	GO:1904158	axonemal central apparatus assembly(GO:1904158)
1.8	8.9	GO:0010693	negative regulation of alkaline phosphatase activity(GO:0010693)
1.8	56.5	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
1.7	10.5	GO:0051964	negative regulation of synapse assembly(GO:0051964)
1.7	27.4	GO:1990403	embryonic brain development(GO:1990403)
1.7	3.4	GO:1990918	double-strand break repair involved in meiotic recombination(GO:1990918)
1.7	11.6	GO:1990169	detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
1.6	4.9	GO:0021577	hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
1.6	3.3	GO:0034729	histone H3-K79 methylation(GO:0034729)
1.6	4.8	GO:1905000	regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
1.6	16.0	GO:2000348	regulation of CD40 signaling pathway(GO:2000348)
1.6	9.6	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
1.6	6.4	GO:0032053	ciliary basal body organization(GO:0032053)
1.6	4.8	GO:0071651	positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
1.6	6.3	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
1.6	15.6	GO:0002315	marginal zone B cell differentiation(GO:0002315)
1.6	6.2	GO:0060265	positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
1.5	47.8	GO:0040034	regulation of development, heterochronic(GO:0040034)
1.5	6.2	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
1.5	15.3	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
1.5	24.4	GO:0033260	nuclear DNA replication(GO:0033260)
1.5	18.3	GO:0019985	translesion synthesis(GO:0019985)
1.5	9.0	GO:0010626	negative regulation of Schwann cell proliferation(GO:0010626)
1.5	7.5	GO:2000002	negative regulation of DNA damage checkpoint(GO:2000002)
1.5	7.5	GO:2000138	positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
1.5	9.0	GO:0033026	negative regulation of mast cell apoptotic process(GO:0033026) mast cell proliferation(GO:0070662) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
1.5	4.4	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
1.5	7.4	GO:0003100	regulation of systemic arterial blood pressure by endothelin(GO:0003100)
1.5	1.5	GO:0010159	specification of organ position(GO:0010159)
1.4	5.8	GO:0060478	acrosomal vesicle exocytosis(GO:0060478)
1.4	5.7	GO:0043987	histone H3-S10 phosphorylation(GO:0043987)
1.4	17.1	GO:0051571	positive regulation of histone H3-K4 methylation(GO:0051571)
1.4	1.4	GO:0000022	mitotic spindle elongation(GO:0000022)
1.4	7.0	GO:0009414	response to water deprivation(GO:0009414)
1.4	4.2	GO:0010825	positive regulation of centrosome duplication(GO:0010825)
1.4	6.9	GO:2000409	positive regulation of T cell extravasation(GO:2000409)
1.4	12.4	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
1.4	10.9	GO:0048102	autophagic cell death(GO:0048102)
1.4	4.1	GO:0006597	spermine biosynthetic process(GO:0006597)
1.3	10.3	GO:0002326	B cell lineage commitment(GO:0002326)
1.3	8.9	GO:0016584	nucleosome positioning(GO:0016584)
1.3	11.4	GO:0006336	DNA replication-independent nucleosome assembly(GO:0006336)
1.3	6.3	GO:1904668	positive regulation of ubiquitin protein ligase activity(GO:1904668)
1.3	5.0	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
1.3	5.0	GO:0060032	notochord regression(GO:0060032)
1.3	7.5	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
1.2	5.0	GO:1903207	neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
1.2	9.8	GO:0071459	protein localization to chromosome, centromeric region(GO:0071459)
1.2	22.1	GO:0016188	synaptic vesicle maturation(GO:0016188)
1.2	17.8	GO:0051382	kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383)
1.2	8.2	GO:0002840	T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
1.2	4.7	GO:0086053	AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
1.2	33.5	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
1.2	11.5	GO:0000185	activation of MAPKKK activity(GO:0000185)
1.1	2.3	GO:0060061	Spemann organizer formation(GO:0060061)
1.1	6.8	GO:0006543	glutamine catabolic process(GO:0006543)
1.1	20.3	GO:0001675	acrosome assembly(GO:0001675)
1.1	4.5	GO:0070634	transepithelial ammonium transport(GO:0070634)
1.1	4.4	GO:0021586	pons maturation(GO:0021586)
1.1	3.3	GO:0014707	branchiomeric skeletal muscle development(GO:0014707)
1.1	6.6	GO:0009099	branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
1.1	6.6	GO:0001866	NK T cell proliferation(GO:0001866)
1.1	13.1	GO:0043117	positive regulation of vascular permeability(GO:0043117)
1.1	12.0	GO:0036123	histone H3-K9 dimethylation(GO:0036123)
1.1	53.4	GO:0090307	mitotic spindle assembly(GO:0090307)
1.1	6.4	GO:0045585	regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
1.1	4.3	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
1.1	10.6	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
1.1	6.3	GO:0006116	NADH oxidation(GO:0006116)
1.1	6.3	GO:0035624	receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
1.1	1.1	GO:2000328	regulation of T-helper 17 cell lineage commitment(GO:2000328)
1.0	11.2	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
1.0	9.9	GO:0010764	negative regulation of fibroblast migration(GO:0010764)
1.0	8.9	GO:0048752	semicircular canal morphogenesis(GO:0048752)
1.0	2.0	GO:0061209	cell proliferation involved in mesonephros development(GO:0061209)
1.0	43.1	GO:0006779	porphyrin-containing compound biosynthetic process(GO:0006779)
1.0	7.8	GO:1904177	regulation of adipose tissue development(GO:1904177)
1.0	5.8	GO:0010025	wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
1.0	2.9	GO:0060435	bronchiole development(GO:0060435)
1.0	9.7	GO:0032534	regulation of microvillus assembly(GO:0032534)
1.0	5.8	GO:0007000	nucleolus organization(GO:0007000)
1.0	28.0	GO:0044381	glucose import in response to insulin stimulus(GO:0044381)
1.0	2.9	GO:0042823	pyridoxal phosphate biosynthetic process(GO:0042823)
1.0	2.9	GO:0098532	histone H3-K27 trimethylation(GO:0098532)
1.0	2.9	GO:0060722	spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
0.9	1.9	GO:0051466	corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.9	3.7	GO:0014043	negative regulation of neuron maturation(GO:0014043)
0.9	8.3	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.9	26.5	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.9	28.0	GO:0045026	plasma membrane fusion(GO:0045026)
0.9	6.3	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.9	5.4	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.9	10.8	GO:0060272	embryonic skeletal joint morphogenesis(GO:0060272)
0.9	6.2	GO:0061087	positive regulation of histone H3-K27 methylation(GO:0061087)
0.9	2.7	GO:0030200	heparan sulfate proteoglycan catabolic process(GO:0030200)
0.9	3.6	GO:0051643	endoplasmic reticulum localization(GO:0051643)
0.9	1.8	GO:0032202	telomere assembly(GO:0032202)
0.9	2.6	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
0.9	2.6	GO:1904046	negative regulation of vascular endothelial growth factor production(GO:1904046)
0.9	1.7	GO:0021938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation(GO:0021938)
0.9	11.2	GO:0070995	NADPH oxidation(GO:0070995)
0.9	10.2	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.8	5.0	GO:0006452	translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.8	1.7	GO:2000301	negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.8	6.5	GO:0010587	miRNA catabolic process(GO:0010587)
0.8	2.4	GO:1902410	mitotic cytokinetic process(GO:1902410)
0.8	11.7	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.8	21.1	GO:0051310	metaphase plate congression(GO:0051310)
0.8	20.2	GO:0048268	clathrin coat assembly(GO:0048268)
0.8	10.8	GO:0043249	erythrocyte maturation(GO:0043249)
0.8	5.4	GO:0050713	negative regulation of translation in response to stress(GO:0032055) negative regulation of interleukin-1 beta secretion(GO:0050713)
0.8	7.6	GO:0019336	phenol-containing compound catabolic process(GO:0019336)
0.8	24.2	GO:0051225	spindle assembly(GO:0051225)
0.8	3.8	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.7	7.4	GO:0051026	chiasma assembly(GO:0051026)
0.7	14.6	GO:0002052	positive regulation of neuroblast proliferation(GO:0002052)
0.7	6.5	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.7	2.9	GO:0006203	dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061)
0.7	2.9	GO:0098795	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.7	2.9	GO:0034508	centromere complex assembly(GO:0034508)
0.7	5.7	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.7	8.5	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.7	2.8	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
0.7	16.3	GO:0032467	positive regulation of cytokinesis(GO:0032467)
0.7	4.9	GO:0098814	spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.7	2.8	GO:0019042	viral latency(GO:0019042)
0.7	11.6	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.7	2.0	GO:0021764	amygdala development(GO:0021764)
0.7	2.0	GO:0060137	maternal process involved in parturition(GO:0060137)
0.7	6.7	GO:0031125	rRNA 3'-end processing(GO:0031125)
0.7	6.0	GO:0051573	negative regulation of histone H3-K9 methylation(GO:0051573)
0.7	12.0	GO:0006353	DNA-templated transcription, termination(GO:0006353)
0.7	9.8	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.6	6.4	GO:0042984	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.6	2.5	GO:0044806	G-quadruplex DNA unwinding(GO:0044806)
0.6	4.4	GO:0009235	cobalamin metabolic process(GO:0009235)
0.6	4.4	GO:2000672	negative regulation of motor neuron apoptotic process(GO:2000672)
0.6	1.2	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.6	1.2	GO:0010579	regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.6	4.2	GO:0036337	Fas signaling pathway(GO:0036337)
0.6	3.0	GO:0035617	stress granule disassembly(GO:0035617)
0.6	3.6	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.6	1.2	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
0.6	12.6	GO:0030903	notochord development(GO:0030903)
0.6	3.0	GO:0015889	cobalamin transport(GO:0015889)
0.6	4.1	GO:0045653	negative regulation of megakaryocyte differentiation(GO:0045653)
0.6	8.3	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.5	1.6	GO:1903279	regulation of calcium:sodium antiporter activity(GO:1903279)
0.5	6.0	GO:0071361	cellular response to ethanol(GO:0071361)
0.5	5.3	GO:0000042	protein targeting to Golgi(GO:0000042)
0.5	4.7	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.5	0.5	GO:0072284	metanephric S-shaped body morphogenesis(GO:0072284) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.5	2.5	GO:0072697	protein localization to cell cortex(GO:0072697)
0.5	12.4	GO:0044342	type B pancreatic cell proliferation(GO:0044342)
0.5	2.5	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.5	6.4	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.5	28.7	GO:0006334	nucleosome assembly(GO:0006334)
0.5	3.3	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055) ribosomal small subunit export from nucleus(GO:0000056) protein localization to nucleolus(GO:1902570)
0.5	3.3	GO:0010724	regulation of definitive erythrocyte differentiation(GO:0010724)
0.5	3.3	GO:0045200	establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.5	10.3	GO:0031069	hair follicle morphogenesis(GO:0031069)
0.5	5.5	GO:0061072	iris morphogenesis(GO:0061072)
0.5	20.7	GO:0043044	ATP-dependent chromatin remodeling(GO:0043044)
0.5	2.3	GO:0061141	lung ciliated cell differentiation(GO:0061141)
0.5	7.2	GO:0032211	negative regulation of telomere maintenance via telomerase(GO:0032211)
0.4	15.7	GO:0006378	mRNA polyadenylation(GO:0006378)
0.4	28.2	GO:0006342	chromatin silencing(GO:0006342)
0.4	0.9	GO:2000670	positive regulation of dendritic cell apoptotic process(GO:2000670)
0.4	6.0	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
0.4	1.7	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.4	2.1	GO:0002760	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.4	9.7	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.4	13.3	GO:0006284	base-excision repair(GO:0006284)
0.4	1.2	GO:1902396	protein localization to bicellular tight junction(GO:1902396)
0.4	0.8	GO:1902174	positive regulation of keratinocyte apoptotic process(GO:1902174)
0.4	3.6	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.4	4.4	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.4	5.2	GO:0098989	NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.4	2.4	GO:0043654	recognition of apoptotic cell(GO:0043654)
0.4	1.6	GO:0033750	ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753)
0.4	0.8	GO:0051984	positive regulation of chromosome segregation(GO:0051984)
0.4	8.6	GO:0007413	axonal fasciculation(GO:0007413)
0.4	2.3	GO:0051574	positive regulation of histone H3-K9 methylation(GO:0051574)
0.4	5.4	GO:0043968	histone H2A acetylation(GO:0043968)
0.4	3.4	GO:0007343	egg activation(GO:0007343)
0.4	5.3	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.4	1.5	GO:0060398	regulation of growth hormone receptor signaling pathway(GO:0060398)
0.4	1.1	GO:0018243	protein O-linked glycosylation via threonine(GO:0018243)
0.4	1.5	GO:0003349	epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.3	5.5	GO:0071688	striated muscle myosin thick filament assembly(GO:0071688)
0.3	4.1	GO:0001682	tRNA 5'-leader removal(GO:0001682)
0.3	10.1	GO:0006706	steroid catabolic process(GO:0006706)
0.3	1.0	GO:0009106	lipoate metabolic process(GO:0009106)
0.3	1.7	GO:0002318	myeloid progenitor cell differentiation(GO:0002318)
0.3	1.0	GO:1904923	regulation of mitophagy in response to mitochondrial depolarization(GO:1904923)
0.3	1.9	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.3	1.6	GO:0021960	anterior commissure morphogenesis(GO:0021960)
0.3	2.6	GO:0045198	establishment of epithelial cell apical/basal polarity(GO:0045198)
0.3	15.8	GO:0043666	regulation of phosphoprotein phosphatase activity(GO:0043666)
0.3	1.0	GO:0070535	histone H2A K63-linked ubiquitination(GO:0070535)
0.3	12.8	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026)
0.3	2.8	GO:0014807	regulation of somitogenesis(GO:0014807)
0.3	2.8	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.3	2.1	GO:0036265	RNA (guanine-N7)-methylation(GO:0036265)
0.3	0.6	GO:0070734	histone H3-K27 methylation(GO:0070734)
0.3	4.2	GO:0030853	negative regulation of granulocyte differentiation(GO:0030853)
0.3	0.9	GO:0023016	signal transduction by trans-phosphorylation(GO:0023016) regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.3	1.2	GO:0044829	positive regulation by host of viral genome replication(GO:0044829)
0.3	9.0	GO:0035307	positive regulation of protein dephosphorylation(GO:0035307)
0.3	1.7	GO:2000269	regulation of fibroblast apoptotic process(GO:2000269)
0.3	15.0	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.3	1.4	GO:0033631	cell-cell adhesion mediated by integrin(GO:0033631)
0.3	0.8	GO:0061090	positive regulation of sequestering of zinc ion(GO:0061090)
0.3	1.7	GO:1990928	response to amino acid starvation(GO:1990928)
0.3	8.9	GO:0006099	tricarboxylic acid cycle(GO:0006099)
0.3	3.0	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
0.3	2.5	GO:0042989	sequestering of actin monomers(GO:0042989)
0.3	3.0	GO:0000470	maturation of LSU-rRNA(GO:0000470)
0.3	10.0	GO:0048247	lymphocyte chemotaxis(GO:0048247)
0.3	2.1	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.3	0.3	GO:1903919	regulation of actin filament severing(GO:1903918) negative regulation of actin filament severing(GO:1903919)
0.3	1.0	GO:0031860	telomeric 3' overhang formation(GO:0031860)
0.3	0.8	GO:0060715	syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.3	2.3	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.3	1.8	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.2	12.7	GO:0001954	positive regulation of cell-matrix adhesion(GO:0001954)
0.2	1.4	GO:0035562	negative regulation of chromatin binding(GO:0035562)
0.2	5.4	GO:0008340	determination of adult lifespan(GO:0008340)
0.2	2.5	GO:0036010	protein localization to endosome(GO:0036010)
0.2	1.6	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.2	4.1	GO:1903861	positive regulation of dendrite extension(GO:1903861)
0.2	1.3	GO:0035022	positive regulation of Rac protein signal transduction(GO:0035022)
0.2	1.1	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.2	2.0	GO:0035385	Roundabout signaling pathway(GO:0035385)
0.2	0.4	GO:0036016	response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.2	1.6	GO:0071896	protein localization to adherens junction(GO:0071896)
0.2	1.1	GO:0006682	galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2	4.4	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.2	9.8	GO:0005979	regulation of glycogen biosynthetic process(GO:0005979) regulation of glucan biosynthetic process(GO:0010962)
0.2	2.4	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.2	3.7	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.2	1.3	GO:0033227	positive regulation of synaptic transmission, dopaminergic(GO:0032226) dsRNA transport(GO:0033227)
0.2	0.4	GO:0033566	gamma-tubulin complex localization(GO:0033566)
0.2	1.1	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.2	7.7	GO:0009409	response to cold(GO:0009409)
0.2	1.0	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.2	0.6	GO:0061428	peptidyl-aspartic acid hydroxylation(GO:0042264) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.2	1.0	GO:0097503	sialylation(GO:0097503)
0.2	5.9	GO:0033045	regulation of sister chromatid segregation(GO:0033045)
0.2	1.4	GO:2000786	positive regulation of autophagosome assembly(GO:2000786)
0.2	3.2	GO:1900027	regulation of ruffle assembly(GO:1900027)
0.2	1.8	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.2	2.0	GO:2000001	regulation of DNA damage checkpoint(GO:2000001)
0.2	0.6	GO:0060244	negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.2	1.2	GO:0070601	centromeric sister chromatid cohesion(GO:0070601)
0.2	0.8	GO:0021506	anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.2	0.6	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2	8.1	GO:0060976	coronary vasculature development(GO:0060976)
0.2	1.1	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.2	0.6	GO:0042275	error-free postreplication DNA repair(GO:0042275)
0.2	1.3	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.2	3.5	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.2	3.1	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.2	0.5	GO:0032510	endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.2	2.9	GO:0006743	ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.2	1.3	GO:0035457	cellular response to interferon-alpha(GO:0035457)
0.2	5.5	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.2	0.5	GO:0042339	keratan sulfate metabolic process(GO:0042339)
0.2	1.9	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.2	1.3	GO:0045631	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.2	0.8	GO:1905169	protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.2	1.5	GO:0072395	signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422)
0.2	0.5	GO:0044208	'de novo' AMP biosynthetic process(GO:0044208)
0.2	5.9	GO:0045599	negative regulation of fat cell differentiation(GO:0045599)
0.2	1.4	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.2	1.1	GO:0035563	regulation of chromatin binding(GO:0035561) positive regulation of chromatin binding(GO:0035563)
0.2	1.4	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.2	3.2	GO:0032098	regulation of appetite(GO:0032098)
0.2	1.5	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.2	0.5	GO:0060060	positive regulation of axon extension involved in axon guidance(GO:0048842) post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.1	1.9	GO:0097264	self proteolysis(GO:0097264)
0.1	9.5	GO:0051028	mRNA transport(GO:0051028)
0.1	3.5	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
0.1	0.7	GO:0031053	primary miRNA processing(GO:0031053)
0.1	2.4	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.1	0.4	GO:1903288	positive regulation of potassium ion import(GO:1903288)
0.1	5.1	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1	2.4	GO:0006817	phosphate ion transport(GO:0006817)
0.1	8.3	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.1	4.3	GO:0035025	positive regulation of Rho protein signal transduction(GO:0035025)
0.1	3.7	GO:0018345	protein palmitoylation(GO:0018345)
0.1	1.4	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.1	7.6	GO:0048477	oogenesis(GO:0048477)
0.1	0.2	GO:0072708	response to sorbitol(GO:0072708)
0.1	4.2	GO:0071300	cellular response to retinoic acid(GO:0071300)
0.1	2.6	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1	0.3	GO:0043697	dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.1	0.7	GO:0016266	O-glycan processing(GO:0016266)
0.1	7.6	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
0.1	2.1	GO:0046855	inositol phosphate dephosphorylation(GO:0046855)
0.1	0.4	GO:0010286	heat acclimation(GO:0010286)
0.1	1.1	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1	0.1	GO:0045041	protein import into mitochondrial intermembrane space(GO:0045041)
0.1	1.9	GO:0030539	male genitalia development(GO:0030539)
0.1	3.0	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.1	0.5	GO:0034351	regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351) positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1	2.3	GO:0007097	nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1	0.5	GO:0043981	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.1	0.7	GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.1	7.4	GO:0000910	cytokinesis(GO:0000910)
0.1	1.1	GO:0070208	protein heterotrimerization(GO:0070208)
0.1	1.3	GO:0006907	pinocytosis(GO:0006907)
0.1	0.9	GO:0070203	regulation of establishment of protein localization to telomere(GO:0070203) positive regulation of establishment of protein localization to telomere(GO:1904851)
0.1	3.3	GO:0043966	histone H3 acetylation(GO:0043966)
0.1	2.1	GO:0048854	brain morphogenesis(GO:0048854)
0.1	4.3	GO:0032755	positive regulation of interleukin-6 production(GO:0032755)
0.1	0.6	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.1	1.7	GO:0033627	cell adhesion mediated by integrin(GO:0033627)
0.1	0.4	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.1	1.5	GO:0035065	regulation of histone acetylation(GO:0035065)
0.1	0.5	GO:0046325	negative regulation of glucose transport(GO:0010829) negative regulation of glucose import(GO:0046325)
0.1	1.5	GO:0003416	endochondral bone growth(GO:0003416)
0.1	0.2	GO:1902732	positive regulation of chondrocyte proliferation(GO:1902732)
0.1	11.1	GO:0000398	RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.1	0.2	GO:1902525	regulation of protein monoubiquitination(GO:1902525)
0.1	0.2	GO:0002191	cap-dependent translational initiation(GO:0002191)
0.1	1.2	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.1	0.5	GO:0010972	negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1	0.3	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	2.2	GO:0033344	cholesterol efflux(GO:0033344)
0.1	0.3	GO:0051775	response to redox state(GO:0051775)
0.0	1.7	GO:0050710	negative regulation of cytokine secretion(GO:0050710)
0.0	3.7	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.2	GO:0061386	closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0	0.7	GO:0032695	negative regulation of interleukin-12 production(GO:0032695)
0.0	0.1	GO:0034398	telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0	1.3	GO:0006910	phagocytosis, recognition(GO:0006910)
0.0	1.5	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
0.0	0.3	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.6	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.7	GO:0000070	mitotic sister chromatid segregation(GO:0000070)
0.0	0.6	GO:0060088	auditory receptor cell stereocilium organization(GO:0060088)
0.0	1.9	GO:1902017	regulation of cilium assembly(GO:1902017)
0.0	1.3	GO:0043484	regulation of RNA splicing(GO:0043484)
0.0	0.5	GO:0048147	negative regulation of fibroblast proliferation(GO:0048147)
0.0	0.2	GO:2000300	regulation of synaptic vesicle exocytosis(GO:2000300)
0.0	0.2	GO:1900121	negative regulation of receptor binding(GO:1900121)
0.0	0.5	GO:0034389	lipid particle organization(GO:0034389)
0.0	0.4	GO:0007019	microtubule depolymerization(GO:0007019)
0.0	1.2	GO:0006879	cellular iron ion homeostasis(GO:0006879)
0.0	0.2	GO:0006020	inositol metabolic process(GO:0006020)
0.0	1.0	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.1	GO:0033572	transferrin transport(GO:0033572)
0.0	0.7	GO:0007093	mitotic cell cycle checkpoint(GO:0007093)
0.0	0.1	GO:0030828	positive regulation of cGMP biosynthetic process(GO:0030828)
0.0	0.9	GO:0030010	establishment of cell polarity(GO:0030010)
0.0	0.1	GO:0080182	histone H3-K4 trimethylation(GO:0080182)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
11.3	56.7	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
9.1	45.5	GO:0031523	Myb complex(GO:0031523)
9.0	134.7	GO:0042555	MCM complex(GO:0042555)
8.6	25.7	GO:0097135	cyclin E2-CDK2 complex(GO:0097135)
8.5	25.4	GO:0033186	CAF-1 complex(GO:0033186)
6.9	69.1	GO:0000796	condensin complex(GO:0000796)
6.2	37.2	GO:0098536	deuterosome(GO:0098536)
5.9	17.8	GO:1990423	RZZ complex(GO:1990423)
4.8	33.8	GO:0008091	spectrin(GO:0008091)
4.7	19.0	GO:0090537	CERF complex(GO:0090537)
4.1	12.3	GO:0071920	cleavage body(GO:0071920)
4.1	12.2	GO:0005656	nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
4.0	20.0	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
3.6	14.3	GO:0019034	viral replication complex(GO:0019034) dendritic filopodium(GO:1902737)
3.6	17.8	GO:0097149	centralspindlin complex(GO:0097149)
3.5	21.2	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
3.4	30.2	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
3.0	12.1	GO:0000802	transverse filament(GO:0000802)
3.0	9.0	GO:0071149	TEAD-2-YAP complex(GO:0071149)
2.8	22.2	GO:0042382	paraspeckles(GO:0042382)
2.6	10.4	GO:0043293	apoptosome(GO:0043293)
2.4	9.7	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
2.4	7.2	GO:0000939	condensed chromosome inner kinetochore(GO:0000939)
2.3	20.8	GO:0030991	intraciliary transport particle A(GO:0030991)
2.3	20.6	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
2.3	11.3	GO:0035189	Rb-E2F complex(GO:0035189)
2.2	15.4	GO:0005638	lamin filament(GO:0005638)
2.1	144.5	GO:0005657	replication fork(GO:0005657)
2.1	29.4	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
2.0	8.1	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
2.0	22.2	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
2.0	14.0	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
2.0	9.8	GO:0071914	prominosome(GO:0071914)
1.9	5.7	GO:0005673	transcription factor TFIIE complex(GO:0005673)
1.9	7.5	GO:0099522	region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
1.9	31.6	GO:0032593	insulin-responsive compartment(GO:0032593)
1.8	59.2	GO:0051233	spindle midzone(GO:0051233)
1.8	5.4	GO:1990716	axonemal central apparatus(GO:1990716)
1.8	17.6	GO:0072687	meiotic spindle(GO:0072687)
1.7	6.9	GO:0008623	CHRAC(GO:0008623)
1.7	11.8	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
1.7	13.4	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
1.6	13.0	GO:0070652	HAUS complex(GO:0070652)
1.6	21.0	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
1.6	9.7	GO:0044530	supraspliceosomal complex(GO:0044530)
1.6	16.0	GO:0005652	nuclear lamina(GO:0005652)
1.6	16.0	GO:0044214	spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
1.6	4.8	GO:0031417	NatC complex(GO:0031417)
1.5	3.0	GO:0005945	6-phosphofructokinase complex(GO:0005945)
1.5	4.4	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
1.4	10.1	GO:0001740	Barr body(GO:0001740)
1.4	14.4	GO:0001739	sex chromatin(GO:0001739)
1.3	2.7	GO:0031510	SUMO activating enzyme complex(GO:0031510)
1.2	6.2	GO:0044615	nuclear pore nuclear basket(GO:0044615)
1.2	25.5	GO:0010369	chromocenter(GO:0010369)
1.2	6.0	GO:0070876	SOSS complex(GO:0070876)
1.2	10.6	GO:0097442	CA3 pyramidal cell dendrite(GO:0097442)
1.1	6.9	GO:0070531	BRCA1-A complex(GO:0070531)
1.1	38.8	GO:0000788	nuclear nucleosome(GO:0000788)
1.1	11.3	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
1.1	5.6	GO:0044301	climbing fiber(GO:0044301)
1.1	3.3	GO:0031074	nucleocytoplasmic shuttling complex(GO:0031074)
1.1	4.4	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
1.1	10.8	GO:0045298	tubulin complex(GO:0045298)
1.1	6.4	GO:0031933	telomeric heterochromatin(GO:0031933)
1.0	4.1	GO:0033553	rDNA heterochromatin(GO:0033553)
1.0	21.1	GO:0035098	ESC/E(Z) complex(GO:0035098)
1.0	5.0	GO:1990037	Lewy body core(GO:1990037)
1.0	12.7	GO:0031616	spindle pole centrosome(GO:0031616)
1.0	13.6	GO:0097539	ciliary transition fiber(GO:0097539)
1.0	53.6	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.9	68.0	GO:0005844	polysome(GO:0005844)
0.9	5.6	GO:0071547	piP-body(GO:0071547)
0.9	15.7	GO:0044453	nuclear membrane part(GO:0044453)
0.9	10.1	GO:0005687	U4 snRNP(GO:0005687)
0.9	5.5	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.9	8.0	GO:0097431	mitotic spindle pole(GO:0097431)
0.8	9.3	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.8	8.8	GO:0000974	Prp19 complex(GO:0000974)
0.8	6.2	GO:0097433	dense body(GO:0097433)
0.8	4.6	GO:0000923	equatorial microtubule organizing center(GO:0000923)
0.8	5.4	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.8	13.6	GO:0031143	pseudopodium(GO:0031143)
0.7	6.6	GO:0061574	ASAP complex(GO:0061574)
0.7	2.1	GO:0031533	mRNA cap methyltransferase complex(GO:0031533)
0.7	12.0	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
0.7	25.3	GO:0000786	nucleosome(GO:0000786)
0.7	2.0	GO:0030870	Mre11 complex(GO:0030870)
0.7	4.1	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.7	6.1	GO:0000782	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.7	65.8	GO:0005814	centriole(GO:0005814)
0.6	19.6	GO:0097228	sperm principal piece(GO:0097228)
0.6	1.8	GO:0030905	retromer, tubulation complex(GO:0030905)
0.6	6.9	GO:0005686	U2 snRNP(GO:0005686)
0.5	4.9	GO:0044666	MLL3/4 complex(GO:0044666)
0.5	22.9	GO:0015030	Cajal body(GO:0015030)
0.5	8.0	GO:0005721	pericentric heterochromatin(GO:0005721)
0.5	6.9	GO:0036038	MKS complex(GO:0036038)
0.5	8.2	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.5	42.4	GO:0016363	nuclear matrix(GO:0016363)
0.5	1.0	GO:0035976	AP1 complex(GO:0035976)
0.5	9.9	GO:0035869	ciliary transition zone(GO:0035869)
0.5	22.5	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.5	5.0	GO:0097542	ciliary tip(GO:0097542)
0.4	13.9	GO:0002080	acrosomal membrane(GO:0002080)
0.4	10.3	GO:0005680	anaphase-promoting complex(GO:0005680)
0.4	25.9	GO:0000784	nuclear chromosome, telomeric region(GO:0000784)
0.4	1.3	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.4	13.7	GO:0005719	nuclear euchromatin(GO:0005719)
0.4	69.5	GO:0000775	chromosome, centromeric region(GO:0000775)
0.4	21.3	GO:0045171	intercellular bridge(GO:0045171)
0.4	2.1	GO:0034709	methylosome(GO:0034709)
0.4	2.1	GO:0090533	cation-transporting ATPase complex(GO:0090533)
0.4	1.7	GO:0033010	paranodal junction(GO:0033010)
0.4	6.9	GO:0031528	microvillus membrane(GO:0031528)
0.4	1.2	GO:1990590	ATF1-ATF4 transcription factor complex(GO:1990590)
0.4	3.0	GO:0061689	tricellular tight junction(GO:0061689)
0.4	17.2	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.4	55.3	GO:0001650	fibrillar center(GO:0001650)
0.3	1.0	GO:0030690	Noc1p-Noc2p complex(GO:0030690)
0.3	3.8	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.3	3.4	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.3	8.3	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.3	25.2	GO:0005905	clathrin-coated pit(GO:0005905)
0.3	4.5	GO:0043083	synaptic cleft(GO:0043083)
0.3	3.2	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
0.3	2.2	GO:0090543	Flemming body(GO:0090543)
0.3	3.5	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.3	15.0	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.3	2.2	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.3	11.4	GO:0016592	mediator complex(GO:0016592)
0.3	5.9	GO:0044224	juxtaparanode region of axon(GO:0044224)
0.3	4.3	GO:0005685	U1 snRNP(GO:0005685)
0.3	19.8	GO:0017053	transcriptional repressor complex(GO:0017053)
0.3	3.4	GO:0043020	NADPH oxidase complex(GO:0043020)
0.3	2.7	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.3	3.0	GO:0035253	ciliary rootlet(GO:0035253)
0.3	7.7	GO:0035145	exon-exon junction complex(GO:0035145)
0.3	3.0	GO:0000138	Golgi trans cisterna(GO:0000138)
0.3	16.4	GO:0016605	PML body(GO:0016605)
0.3	184.3	GO:0005694	chromosome(GO:0005694)
0.3	1.1	GO:0032021	NELF complex(GO:0032021)
0.3	4.6	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.3	1.7	GO:0097165	nuclear stress granule(GO:0097165)
0.3	0.8	GO:0071953	elastic fiber(GO:0071953)
0.3	3.5	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.3	2.9	GO:0045179	apical cortex(GO:0045179)
0.3	1.3	GO:0001931	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.2	1.7	GO:0044294	dendritic growth cone(GO:0044294)
0.2	0.7	GO:1903095	microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.2	5.5	GO:0005859	muscle myosin complex(GO:0005859)
0.2	7.5	GO:0097440	apical dendrite(GO:0097440)
0.2	34.2	GO:0005681	spliceosomal complex(GO:0005681)
0.2	15.6	GO:0005643	nuclear pore(GO:0005643)
0.2	1.3	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.2	0.8	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.2	1.2	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.2	1.6	GO:0031209	SCAR complex(GO:0031209)
0.2	2.7	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.2	1.5	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.2	3.6	GO:0005614	interstitial matrix(GO:0005614)
0.2	2.4	GO:0001891	phagocytic cup(GO:0001891)
0.2	29.8	GO:0001726	ruffle(GO:0001726)
0.2	5.0	GO:0016591	DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.2	1.4	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.2	1.5	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.1	2.4	GO:0002102	podosome(GO:0002102)
0.1	0.9	GO:0032983	kainate selective glutamate receptor complex(GO:0032983)
0.1	1.4	GO:0034399	nuclear periphery(GO:0034399)
0.1	0.6	GO:1990696	USH2 complex(GO:1990696)
0.1	0.6	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.1	10.0	GO:0030175	filopodium(GO:0030175)
0.1	2.3	GO:0071339	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1	4.4	GO:0016459	myosin complex(GO:0016459)
0.1	0.5	GO:0031084	BLOC-2 complex(GO:0031084)
0.1	0.9	GO:0071203	WASH complex(GO:0071203)
0.1	0.2	GO:0005608	laminin-3 complex(GO:0005608)
0.1	2.4	GO:0031519	PcG protein complex(GO:0031519)
0.1	7.2	GO:0099501	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.1	0.9	GO:0061617	MICOS complex(GO:0061617)
0.1	2.7	GO:0030686	90S preribosome(GO:0030686)
0.1	27.7	GO:0043292	contractile fiber(GO:0043292)
0.1	0.8	GO:0045120	pronucleus(GO:0045120)
0.1	2.7	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.1	1.8	GO:0030137	COPI-coated vesicle(GO:0030137)
0.1	1.4	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.1	1.2	GO:0032279	asymmetric synapse(GO:0032279)
0.1	0.9	GO:0031083	BLOC-1 complex(GO:0031083)
0.1	1.4	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	0.4	GO:0000930	gamma-tubulin complex(GO:0000930)
0.1	7.1	GO:0005581	collagen trimer(GO:0005581)
0.1	1.1	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.1	0.5	GO:0005732	small nucleolar ribonucleoprotein complex(GO:0005732)
0.1	0.6	GO:0031415	NatA complex(GO:0031415)
0.1	6.5	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
0.1	6.1	GO:0005882	intermediate filament(GO:0005882)
0.1	0.8	GO:1904115	axon cytoplasm(GO:1904115)
0.1	0.9	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.1	5.9	GO:0005811	lipid particle(GO:0005811)
0.1	0.3	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.1	0.4	GO:0030665	clathrin-coated vesicle membrane(GO:0030665)
0.1	3.1	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.1	10.1	GO:0043209	myelin sheath(GO:0043209)
0.1	0.8	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	27.8	GO:0005730	nucleolus(GO:0005730)
0.0	3.6	GO:0005604	basement membrane(GO:0005604)
0.0	4.7	GO:0043204	perikaryon(GO:0043204)
0.0	0.7	GO:0030118	clathrin coat(GO:0030118)
0.0	7.0	GO:0005802	trans-Golgi network(GO:0005802)
0.0	0.1	GO:0031501	mannosyltransferase complex(GO:0031501)
0.0	4.1	GO:0072562	blood microparticle(GO:0072562)
0.0	1.3	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.2	GO:0090544	BAF-type complex(GO:0090544)
0.0	2.3	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.9	GO:0030496	midbody(GO:0030496)
0.0	0.1	GO:0035097	histone methyltransferase complex(GO:0035097)
0.0	0.5	GO:0030173	integral component of Golgi membrane(GO:0030173)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
13.7	82.3	GO:0031493	nucleosomal histone binding(GO:0031493)
11.3	56.7	GO:0061731	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
10.3	61.5	GO:0010997	anaphase-promoting complex binding(GO:0010997)
9.1	27.3	GO:0047192	1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
9.1	27.3	GO:0052901	polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
9.0	45.0	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
6.3	19.0	GO:0070615	nucleosome-dependent ATPase activity(GO:0070615)
6.2	18.5	GO:0031896	V2 vasopressin receptor binding(GO:0031896)
5.7	28.5	GO:0043515	kinetochore binding(GO:0043515)
5.6	16.9	GO:0030116	glial cell-derived neurotrophic factor receptor binding(GO:0030116)
4.9	54.1	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
4.9	4.9	GO:0015616	DNA translocase activity(GO:0015616)
4.3	17.1	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
4.3	12.8	GO:0071207	histone pre-mRNA stem-loop binding(GO:0071207)
3.9	19.5	GO:0042895	antibiotic transporter activity(GO:0042895)
3.6	7.2	GO:0000405	bubble DNA binding(GO:0000405)
3.6	18.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
3.1	15.7	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
3.1	12.5	GO:0017108	5'-flap endonuclease activity(GO:0017108)
3.1	18.6	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
3.1	33.9	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
3.0	8.9	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
2.9	8.7	GO:0052740	phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
2.8	22.0	GO:0043559	insulin binding(GO:0043559)
2.6	107.7	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
2.6	12.9	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
2.6	15.5	GO:0061649	ubiquitinated histone binding(GO:0061649)
2.5	7.6	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
2.5	7.5	GO:0004088	carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
2.5	22.2	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
2.4	9.6	GO:0017095	heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
2.4	14.3	GO:0033592	RNA strand annealing activity(GO:0033592)
2.3	9.4	GO:0004488	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
2.3	14.0	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
2.2	17.5	GO:0070087	chromo shadow domain binding(GO:0070087)
2.0	8.0	GO:0031708	endothelin B receptor binding(GO:0031708)
2.0	6.0	GO:0032137	guanine/thymine mispair binding(GO:0032137)
2.0	17.9	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
2.0	11.7	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
1.9	7.7	GO:0044729	hemi-methylated DNA-binding(GO:0044729)
1.9	5.7	GO:0032129	histone deacetylase activity (H3-K9 specific)(GO:0032129) NAD-dependent histone deacetylase activity (H3-K9 specific)(GO:0046969)
1.8	9.2	GO:0036310	annealing helicase activity(GO:0036310) annealing activity(GO:0097617)
1.8	14.6	GO:0061676	importin-alpha family protein binding(GO:0061676)
1.8	5.4	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
1.8	16.1	GO:0043023	ribosomal large subunit binding(GO:0043023)
1.7	12.2	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
1.7	58.5	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
1.7	6.9	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
1.6	22.7	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
1.6	6.3	GO:0004938	alpha2-adrenergic receptor activity(GO:0004938)
1.5	6.2	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
1.5	7.5	GO:0030621	U4 snRNA binding(GO:0030621)
1.5	9.0	GO:0005173	stem cell factor receptor binding(GO:0005173)
1.5	10.3	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
1.5	8.8	GO:0001602	pancreatic polypeptide receptor activity(GO:0001602)
1.4	15.8	GO:1990825	sequence-specific mRNA binding(GO:1990825)
1.4	8.6	GO:0004852	uroporphyrinogen-III synthase activity(GO:0004852)
1.4	10.0	GO:0003678	DNA helicase activity(GO:0003678)
1.4	15.2	GO:0001609	G-protein coupled adenosine receptor activity(GO:0001609)
1.3	4.0	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
1.3	8.1	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
1.3	10.6	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
1.3	4.0	GO:0031751	D4 dopamine receptor binding(GO:0031751)
1.3	55.5	GO:0070412	R-SMAD binding(GO:0070412)
1.3	5.1	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
1.3	3.8	GO:0047179	platelet-activating factor acetyltransferase activity(GO:0047179)
1.2	4.9	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
1.2	4.8	GO:0000700	mismatch base pair DNA N-glycosylase activity(GO:0000700)
1.2	14.3	GO:0030346	protein phosphatase 2B binding(GO:0030346)
1.2	4.7	GO:0086077	gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
1.2	5.8	GO:0080019	fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
1.2	4.6	GO:0052798	beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
1.2	9.2	GO:0070644	vitamin D response element binding(GO:0070644)
1.1	14.6	GO:0008656	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
1.1	7.8	GO:0042289	MHC class II protein binding(GO:0042289)
1.1	6.6	GO:0043237	laminin-1 binding(GO:0043237)
1.1	3.3	GO:0070137	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
1.1	6.6	GO:0052654	branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
1.0	8.3	GO:0030267	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
1.0	32.2	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
1.0	18.5	GO:0008253	5'-nucleotidase activity(GO:0008253)
1.0	4.8	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.9	10.4	GO:0001134	transcription factor activity, transcription factor recruiting(GO:0001134)
0.9	2.8	GO:0019002	GMP binding(GO:0019002)
0.9	10.3	GO:0003680	AT DNA binding(GO:0003680)
0.9	7.5	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.9	5.5	GO:0004359	glutaminase activity(GO:0004359)
0.9	2.7	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.9	27.1	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.9	11.1	GO:0098505	G-rich strand telomeric DNA binding(GO:0098505)
0.8	25.7	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.8	2.5	GO:0001156	TFIIIC-class transcription factor binding(GO:0001156)
0.8	2.4	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.8	5.7	GO:0045545	syndecan binding(GO:0045545)
0.8	2.3	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
0.8	5.3	GO:0015099	nickel cation transmembrane transporter activity(GO:0015099)
0.7	4.4	GO:0008172	S-methyltransferase activity(GO:0008172)
0.7	5.2	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.7	2.2	GO:0030519	snoRNP binding(GO:0030519)
0.7	2.9	GO:0050347	trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.7	5.0	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.7	2.1	GO:0004482	mRNA (guanine-N7-)-methyltransferase activity(GO:0004482)
0.7	2.1	GO:0009041	uridylate kinase activity(GO:0009041) nucleoside phosphate kinase activity(GO:0050145)
0.7	10.3	GO:0032552	deoxyribonucleotide binding(GO:0032552)
0.7	7.5	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.7	14.9	GO:0035173	histone kinase activity(GO:0035173)
0.7	36.4	GO:0070063	RNA polymerase binding(GO:0070063)
0.7	5.4	GO:0050897	cobalt ion binding(GO:0050897)
0.7	34.7	GO:0042169	SH2 domain binding(GO:0042169)
0.7	2.0	GO:0008311	double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.7	2.6	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.7	26.4	GO:0030506	ankyrin binding(GO:0030506)
0.7	3.3	GO:0001165	RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.6	5.7	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.6	13.4	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.6	6.3	GO:0008296	3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.6	26.9	GO:0003755	peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.6	5.5	GO:0022833	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.6	6.1	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.6	6.0	GO:0051011	microtubule minus-end binding(GO:0051011)
0.6	3.6	GO:0019103	pyrimidine nucleotide binding(GO:0019103)
0.6	8.3	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.6	4.1	GO:0019808	polyamine binding(GO:0019808)
0.6	2.3	GO:0002151	G-quadruplex RNA binding(GO:0002151)
0.6	3.4	GO:0044547	DNA topoisomerase binding(GO:0044547)
0.6	8.5	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.6	25.9	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.6	5.6	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.6	4.4	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.6	2.8	GO:0033188	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.5	2.2	GO:2001069	glycogen binding(GO:2001069)
0.5	1.6	GO:0046965	retinoid X receptor binding(GO:0046965)
0.5	63.1	GO:0004386	helicase activity(GO:0004386)
0.5	5.2	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.5	8.1	GO:0004016	adenylate cyclase activity(GO:0004016)
0.5	5.5	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.5	12.5	GO:0043274	phospholipase binding(GO:0043274)
0.5	2.5	GO:0042979	ornithine decarboxylase regulator activity(GO:0042979)
0.5	6.4	GO:0005522	profilin binding(GO:0005522)
0.5	4.4	GO:0097157	pre-mRNA intronic binding(GO:0097157)
0.5	5.8	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.5	2.4	GO:0035614	snRNA stem-loop binding(GO:0035614)
0.5	2.4	GO:0030983	mismatched DNA binding(GO:0030983)
0.5	94.1	GO:0042393	histone binding(GO:0042393)
0.5	8.9	GO:0030215	semaphorin receptor binding(GO:0030215)
0.5	25.7	GO:0070888	E-box binding(GO:0070888)
0.5	33.2	GO:0003697	single-stranded DNA binding(GO:0003697)
0.5	1.4	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.5	11.2	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.5	4.2	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.4	1.8	GO:1990460	leptin receptor binding(GO:1990460)
0.4	4.4	GO:0016175	superoxide-generating NADPH oxidase activity(GO:0016175)
0.4	8.3	GO:0032794	GTPase activating protein binding(GO:0032794)
0.4	1.3	GO:0071209	U7 snRNA binding(GO:0071209)
0.4	2.1	GO:1990188	euchromatin binding(GO:1990188)
0.4	2.0	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.4	8.2	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.4	1.9	GO:0071253	connexin binding(GO:0071253)
0.4	2.7	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.4	3.4	GO:0001055	RNA polymerase II activity(GO:0001055)
0.4	4.4	GO:0016868	intramolecular transferase activity, phosphotransferases(GO:0016868)
0.4	4.1	GO:0004526	ribonuclease P activity(GO:0004526)
0.4	0.7	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.4	6.5	GO:0004707	MAP kinase activity(GO:0004707)
0.4	10.9	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
0.3	1.7	GO:0038132	neuregulin binding(GO:0038132)
0.3	10.5	GO:0001968	fibronectin binding(GO:0001968)
0.3	2.6	GO:0070990	snRNP binding(GO:0070990) U1 snRNP binding(GO:1990446)
0.3	0.6	GO:0071532	ankyrin repeat binding(GO:0071532)
0.3	1.5	GO:0005113	patched binding(GO:0005113)
0.3	1.5	GO:0004724	magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.3	31.5	GO:0003777	microtubule motor activity(GO:0003777)
0.3	2.1	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.3	13.1	GO:0031491	nucleosome binding(GO:0031491)
0.3	6.2	GO:0033613	activating transcription factor binding(GO:0033613)
0.3	1.7	GO:0003705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.3	2.0	GO:0055104	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.3	6.2	GO:0017075	syntaxin-1 binding(GO:0017075)
0.3	4.1	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.3	3.8	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.3	4.6	GO:0010181	FMN binding(GO:0010181)
0.3	2.4	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091) CTD phosphatase activity(GO:0008420)
0.3	1.3	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.3	2.9	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.3	10.0	GO:0008009	chemokine activity(GO:0008009)
0.3	2.0	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.3	3.3	GO:0018024	histone-lysine N-methyltransferase activity(GO:0018024)
0.2	7.2	GO:0017025	TBP-class protein binding(GO:0017025)
0.2	0.5	GO:0016842	amidine-lyase activity(GO:0016842)
0.2	4.3	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.2	1.4	GO:0015440	peptide-transporting ATPase activity(GO:0015440)
0.2	1.4	GO:0051733	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.2	14.5	GO:0031490	chromatin DNA binding(GO:0031490)
0.2	2.3	GO:0070739	protein-glutamic acid ligase activity(GO:0070739)
0.2	2.3	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2	4.3	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.2	2.9	GO:1990226	histone methyltransferase binding(GO:1990226)
0.2	6.1	GO:0070840	dynein complex binding(GO:0070840)
0.2	2.2	GO:0008527	taste receptor activity(GO:0008527)
0.2	2.8	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.2	5.0	GO:0003746	translation elongation factor activity(GO:0003746)
0.2	2.1	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.2	4.8	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.2	10.8	GO:0001786	phosphatidylserine binding(GO:0001786)
0.2	2.5	GO:0048156	tau protein binding(GO:0048156)
0.2	14.5	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.2	7.6	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.2	3.7	GO:0008307	structural constituent of muscle(GO:0008307)
0.2	21.9	GO:0017048	Rho GTPase binding(GO:0017048)
0.2	1.3	GO:0034452	dynactin binding(GO:0034452)
0.2	2.5	GO:0070182	DNA polymerase binding(GO:0070182)
0.2	4.1	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.2	9.8	GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.2	2.1	GO:0050692	DBD domain binding(GO:0050692)
0.2	7.1	GO:0003743	translation initiation factor activity(GO:0003743)
0.2	3.5	GO:0017160	Ral GTPase binding(GO:0017160)
0.2	4.4	GO:0008536	Ran GTPase binding(GO:0008536)
0.2	6.2	GO:0042805	actinin binding(GO:0042805)
0.2	0.3	GO:0001069	regulatory region RNA binding(GO:0001069)
0.2	3.8	GO:0071855	neuropeptide receptor binding(GO:0071855)
0.2	3.5	GO:0004407	histone deacetylase activity(GO:0004407)
0.2	4.8	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.2	3.1	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.2	13.4	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.2	0.8	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.2	6.3	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.1	1.8	GO:0070034	telomerase RNA binding(GO:0070034)
0.1	1.2	GO:0000981	RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.1	6.0	GO:0050699	WW domain binding(GO:0050699)
0.1	0.6	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.1	7.3	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.1	7.0	GO:0005507	copper ion binding(GO:0005507)
0.1	7.3	GO:0019894	kinesin binding(GO:0019894)
0.1	3.7	GO:0017080	sodium channel regulator activity(GO:0017080)
0.1	0.7	GO:0032027	myosin light chain binding(GO:0032027)
0.1	2.8	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.1	3.4	GO:0001104	RNA polymerase II transcription cofactor activity(GO:0001104)
0.1	3.6	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1	4.1	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.1	0.9	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.1	4.3	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.1	1.8	GO:0003796	lysozyme activity(GO:0003796)
0.1	20.8	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1	1.1	GO:0008266	poly(U) RNA binding(GO:0008266)
0.1	10.7	GO:0019902	phosphatase binding(GO:0019902)
0.1	2.3	GO:0032452	histone demethylase activity(GO:0032452)
0.1	0.8	GO:0061665	SUMO ligase activity(GO:0061665)
0.1	15.3	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.1	3.3	GO:0015238	drug transmembrane transporter activity(GO:0015238)
0.1	0.7	GO:0042285	UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1	3.9	GO:0031369	translation initiation factor binding(GO:0031369)
0.1	1.5	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.1	1.3	GO:0042301	phosphate ion binding(GO:0042301)
0.1	3.0	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.1	3.1	GO:0030295	protein kinase activator activity(GO:0030295)
0.1	2.4	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.1	4.8	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1	7.9	GO:0031072	heat shock protein binding(GO:0031072)
0.1	1.5	GO:0070717	poly-purine tract binding(GO:0070717)
0.1	25.4	GO:0003682	chromatin binding(GO:0003682)
0.1	1.2	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.1	3.2	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1	0.5	GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1	39.4	GO:0004674	protein serine/threonine kinase activity(GO:0004674)
0.1	3.9	GO:0005044	scavenger receptor activity(GO:0005044)
0.1	0.2	GO:0097108	hedgehog family protein binding(GO:0097108)
0.1	10.9	GO:0017124	SH3 domain binding(GO:0017124)
0.1	10.1	GO:0005516	calmodulin binding(GO:0005516)
0.1	0.8	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1	1.7	GO:0003774	motor activity(GO:0003774)
0.1	0.7	GO:0008327	methyl-CpG binding(GO:0008327)
0.1	0.9	GO:0005234	extracellular-glutamate-gated ion channel activity(GO:0005234)
0.1	2.4	GO:0001540	beta-amyloid binding(GO:0001540)
0.1	1.1	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.1	0.6	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1	9.7	GO:0004721	phosphoprotein phosphatase activity(GO:0004721)
0.1	18.0	GO:0005525	GTP binding(GO:0005525)
0.0	0.3	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	3.8	GO:0044325	ion channel binding(GO:0044325)
0.0	0.1	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	1.2	GO:0042826	histone deacetylase binding(GO:0042826)
0.0	0.6	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.3	GO:0038191	neuropilin binding(GO:0038191)
0.0	39.4	GO:0003677	DNA binding(GO:0003677)
0.0	0.6	GO:0005158	insulin receptor binding(GO:0005158)
0.0	4.4	GO:0001071	nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0	0.2	GO:1990459	transferrin receptor binding(GO:1990459)
0.0	0.2	GO:0016891	endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.0	0.3	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
4.5	221.3	PID ATR PATHWAY	ATR signaling pathway
2.1	102.3	PID AURORA B PATHWAY	Aurora B signaling
2.1	203.5	PID E2F PATHWAY	E2F transcription factor network
1.1	4.6	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
1.0	28.6	PID ATM PATHWAY	ATM pathway
1.0	23.1	PID FANCONI PATHWAY	Fanconi anemia pathway
1.0	43.7	PID PLK1 PATHWAY	PLK1 signaling events
1.0	33.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.8	29.8	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.7	22.9	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.6	3.7	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.6	8.6	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.6	8.9	PID BARD1 PATHWAY	BARD1 signaling events
0.6	2.9	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.6	10.3	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.5	5.4	PID MYC PATHWAY	C-MYC pathway
0.5	8.0	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.5	23.9	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.5	14.4	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.5	7.3	PID IL5 PATHWAY	IL5-mediated signaling events
0.5	20.2	PID EPHB FWD PATHWAY	EPHB forward signaling
0.5	16.9	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.5	7.3	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.4	6.8	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.4	3.7	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.4	36.4	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.3	32.8	PID CMYB PATHWAY	C-MYB transcription factor network
0.3	12.2	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.3	13.6	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.3	11.5	PID REELIN PATHWAY	Reelin signaling pathway
0.3	9.2	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.3	7.0	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.3	3.2	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.3	3.9	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.3	2.2	PID TNF PATHWAY	TNF receptor signaling pathway
0.3	19.0	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.2	14.6	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.2	12.0	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
0.2	5.3	PID IL1 PATHWAY	IL1-mediated signaling events
0.2	2.1	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.2	10.5	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.2	4.7	PID ENDOTHELIN PATHWAY	Endothelins
0.2	13.3	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.2	1.6	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2	5.0	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.2	33.2	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.2	1.3	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.2	2.1	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.1	1.1	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.1	8.9	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.1	4.1	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.1	5.8	PID P53 REGULATION PATHWAY	p53 pathway
0.1	5.0	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.1	5.1	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.1	3.9	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.1	3.4	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.1	3.7	PID RAC1 PATHWAY	RAC1 signaling pathway
0.1	2.1	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.1	1.7	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.1	1.4	ST GAQ PATHWAY	G alpha q Pathway
0.1	1.8	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.1	4.7	PID PDGFRB PATHWAY	PDGFR-beta signaling pathway
0.1	1.7	PID AMB2 NEUTROPHILS PATHWAY	amb2 Integrin signaling
0.1	0.9	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	0.4	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.1	1.8	PID BMP PATHWAY	BMP receptor signaling
0.1	1.2	PID ERBB4 PATHWAY	ErbB4 signaling events
0.1	18.0	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.1	1.2	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	1.5	PID P73PATHWAY	p73 transcription factor network
0.0	0.3	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.8	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	0.3	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.5	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
8.9	142.6	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
5.7	101.7	REACTOME G1 S SPECIFIC TRANSCRIPTION	Genes involved in G1/S-Specific Transcription
5.1	66.6	REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND	Genes involved in Processive synthesis on the lagging strand
4.6	78.9	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
4.4	8.9	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
3.5	13.9	REACTOME DNA STRAND ELONGATION	Genes involved in DNA strand elongation
3.1	43.1	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
3.0	45.0	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
3.0	29.5	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
2.4	28.6	REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX	Genes involved in Activation of the pre-replicative complex
2.3	11.3	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
2.2	13.5	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
2.0	22.2	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
1.8	26.5	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
1.7	29.6	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
1.6	86.2	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
1.4	38.7	REACTOME KINESINS	Genes involved in Kinesins
1.3	36.1	REACTOME ACYL CHAIN REMODELLING OF PC	Genes involved in Acyl chain remodelling of PC
1.0	6.2	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.8	42.6	REACTOME CLEAVAGE OF GROWING TRANSCRIPT IN THE TERMINATION REGION	Genes involved in Cleavage of Growing Transcript in the Termination Region
0.8	39.7	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS	Genes involved in CREB phosphorylation through the activation of Ras
0.8	9.3	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.8	15.2	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.7	32.8	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.7	17.9	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.7	58.0	REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES	Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.7	18.5	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.7	4.6	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.6	20.8	REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY	Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.6	6.6	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.5	8.1	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.5	26.5	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.5	7.9	REACTOME PHOSPHORYLATION OF THE APC C	Genes involved in Phosphorylation of the APC/C
0.5	9.9	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.5	15.0	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.5	7.0	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.5	4.1	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.5	23.4	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.4	12.8	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.4	4.8	REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.4	22.2	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.4	2.5	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
0.4	2.9	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.4	5.7	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.4	20.0	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.4	11.1	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.4	12.0	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.4	4.8	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.4	8.0	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.4	5.4	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.4	7.9	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.4	10.4	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.4	11.4	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.3	3.8	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.3	13.4	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.3	7.9	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.3	3.4	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.3	6.4	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.3	22.9	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
0.3	1.7	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.3	15.6	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.3	6.4	REACTOME KERATAN SULFATE BIOSYNTHESIS	Genes involved in Keratan sulfate biosynthesis
0.3	7.6	REACTOME ACTIVATED POINT MUTANTS OF FGFR2	Genes involved in Activated point mutants of FGFR2
0.3	5.7	REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT	Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.3	2.3	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.3	5.8	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.3	10.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.3	4.4	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.3	2.7	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.3	20.9	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.3	3.2	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.3	4.8	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.3	1.8	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.2	5.5	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.2	2.7	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.2	2.4	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.2	12.2	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.2	3.5	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
0.2	3.3	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.2	8.4	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.2	3.3	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.2	14.0	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2	2.0	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.2	1.6	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.1	1.6	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.1	0.9	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	1.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1	2.4	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.1	5.3	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1	0.9	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.1	2.3	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1	3.6	REACTOME RNA POL II TRANSCRIPTION	Genes involved in RNA Polymerase II Transcription
0.1	2.9	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.1	0.8	REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.1	2.1	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	1.3	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	2.0	REACTOME G1 PHASE	Genes involved in G1 Phase
0.1	1.2	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
0.1	3.7	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	0.7	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.1	1.1	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.1	8.9	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.1	3.4	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.1	2.1	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	4.8	REACTOME G ALPHA Z SIGNALLING EVENTS	Genes involved in G alpha (z) signalling events
0.1	6.7	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.1	3.3	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1	3.0	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.1	1.4	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1	2.2	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.1	1.9	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.1	2.8	REACTOME SPHINGOLIPID METABOLISM	Genes involved in Sphingolipid metabolism
0.1	1.4	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1	4.4	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	0.9	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0	2.2	REACTOME REGULATION OF APOPTOSIS	Genes involved in Regulation of Apoptosis
0.0	0.7	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.4	REACTOME HOST INTERACTIONS OF HIV FACTORS	Genes involved in Host Interactions of HIV factors
0.0	1.0	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	0.3	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	3.6	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0	1.6	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events

Results for E2f1

Z-value: 5.25

Motif logo

Transcription factors associated with E2f1

Activity-expression correlation:

Activity profile of E2f1 motif

Sorted Z-values of E2f1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of E2f1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: