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GSE58827: Dynamics of the Mouse Liver

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Results for Crx_Gsc

Z-value: 0.81

Motif logo

Transcription factors associated with Crx_Gsc

Gene Symbol Gene ID Gene Info
ENSMUSG00000041578.9 cone-rod homeobox
ENSMUSG00000021095.4 goosecoid homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Gscmm10_v2_chr12_-_104473236_1044733240.344.0e-02Click!
Crxmm10_v2_chr7_-_15879844_158799680.048.3e-01Click!

Activity profile of Crx_Gsc motif

Sorted Z-values of Crx_Gsc motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_87141114 4.82 ENSMUST00000168889.1
diaphanous homolog 3 (Drosophila)
chr7_-_103843154 4.45 ENSMUST00000063957.4
hemoglobin Z, beta-like embryonic chain
chr14_-_87141206 4.17 ENSMUST00000022599.7
diaphanous homolog 3 (Drosophila)
chr14_-_20269162 4.08 ENSMUST00000024155.7
potassium channel, subfamily K, member 16
chr4_-_137430517 3.82 ENSMUST00000102522.4
chymotrypsin-like elastase family, member 3B
chr5_+_90768511 3.40 ENSMUST00000031319.6
pro-platelet basic protein
chr6_+_113531675 3.33 ENSMUST00000036340.5
ENSMUST00000101051.2
Fanconi anemia, complementation group D2
chr3_-_113291449 3.29 ENSMUST00000179568.1
amylase 2a4
chr3_-_113324052 3.15 ENSMUST00000179314.1
amylase 2a3
chr13_-_4150628 3.10 ENSMUST00000110704.2
ENSMUST00000021635.7
aldo-keto reductase family 1, member C18
chr11_-_102107822 2.92 ENSMUST00000177304.1
ENSMUST00000017455.8
peptide YY
chr4_-_137409777 2.63 ENSMUST00000024200.6
predicted gene 13011
chr3_-_113258837 2.59 ENSMUST00000098673.3
amylase 2a5
chr14_-_19977151 2.58 ENSMUST00000055100.7
ENSMUST00000162425.1
guanine nucleotide binding protein (G protein), gamma 2
chr6_-_41035501 2.55 ENSMUST00000031931.5
RIKEN cDNA 2210010C04 gene
chr16_+_33794008 2.53 ENSMUST00000115044.1
mucin 13, epithelial transmembrane
chr14_-_19977040 2.50 ENSMUST00000159028.1
guanine nucleotide binding protein (G protein), gamma 2
chr16_+_33794345 2.47 ENSMUST00000023520.6
mucin 13, epithelial transmembrane
chr8_+_72761868 2.39 ENSMUST00000058099.8
coagulation factor II (thrombin) receptor-like 3
chr5_+_76656512 2.31 ENSMUST00000086909.4
predicted gene 10430
chr14_+_27000362 2.27 ENSMUST00000035433.8
homeobox gene expressed in ES cells
chr3_+_105870858 2.02 ENSMUST00000164730.1
adenosine A3 receptor
chr4_-_63172118 1.99 ENSMUST00000030042.2
kinesin family member 12
chr8_+_117498272 1.98 ENSMUST00000081232.7
phospholipase C, gamma 2
chr11_-_17008647 1.93 ENSMUST00000102881.3
pleckstrin
chr4_-_34050038 1.88 ENSMUST00000084734.4
sperm acrosome associated 1
chr2_-_24763047 1.83 ENSMUST00000100348.3
ENSMUST00000041342.5
ENSMUST00000114447.1
ENSMUST00000102939.2
ENSMUST00000070864.7
calcium channel, voltage-dependent, N type, alpha 1B subunit
chr18_-_74207771 1.76 ENSMUST00000040188.8
ENSMUST00000177604.1
spindle and kinetochore associated complex subunit 1
chr14_-_19977249 1.71 ENSMUST00000160013.1
guanine nucleotide binding protein (G protein), gamma 2
chr4_-_141078302 1.66 ENSMUST00000030760.8
NECAP endocytosis associated 2
chr11_+_95010277 1.63 ENSMUST00000124735.1
sterile alpha motif domain containing 14
chr4_-_34050077 1.60 ENSMUST00000029927.5
sperm acrosome associated 1
chr7_-_110982169 1.53 ENSMUST00000154466.1
MRV integration site 1
chr6_-_136401830 1.49 ENSMUST00000058713.7
RIKEN cDNA E330021D16 gene
chr3_+_105870898 1.49 ENSMUST00000010279.5
adenosine A3 receptor
chr2_+_178430531 1.48 ENSMUST00000108912.2
ENSMUST00000042092.8
cadherin-like 26
chr14_+_65266701 1.46 ENSMUST00000169656.1
F-box protein 16
chr1_-_189688074 1.45 ENSMUST00000171929.1
ENSMUST00000165962.1
centromere protein F
chr7_+_99535652 1.32 ENSMUST00000032995.8
ENSMUST00000162404.1
arrestin, beta 1
chrX_+_7919816 1.32 ENSMUST00000041096.3
proprotein convertase subtilisin/kexin type 1 inhibitor
chr7_+_99535439 1.32 ENSMUST00000098266.2
ENSMUST00000179755.1
arrestin, beta 1
chr8_+_123411424 1.31 ENSMUST00000071134.3
tubulin, beta 3 class III
chr7_-_43533171 1.26 ENSMUST00000004728.5
ENSMUST00000039861.5
CD33 antigen
chr2_+_120476911 1.22 ENSMUST00000110716.1
ENSMUST00000028748.6
ENSMUST00000090028.5
ENSMUST00000110719.2
calpain 3
chr6_-_128826305 1.22 ENSMUST00000174544.1
ENSMUST00000172887.1
ENSMUST00000032472.4
killer cell lectin-like receptor subfamily B member 1B
chr2_-_160912292 1.21 ENSMUST00000109454.1
ENSMUST00000057169.4
elastin microfibril interfacer 3
chr7_-_4752972 1.18 ENSMUST00000183971.1
ENSMUST00000182173.1
ENSMUST00000182738.1
ENSMUST00000184143.1
ENSMUST00000182111.1
ENSMUST00000182048.1
ENSMUST00000063324.7
cytochrome c oxidase subunit VIb polypeptide 2
chr9_-_53975246 1.12 ENSMUST00000048409.7
ELMO/CED-12 domain containing 1
chr10_+_3973086 1.11 ENSMUST00000117291.1
ENSMUST00000120585.1
ENSMUST00000043735.7
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr2_-_164404606 1.10 ENSMUST00000109359.1
ENSMUST00000109358.1
ENSMUST00000103103.3
matrilin 4
chr10_-_62327757 1.09 ENSMUST00000139228.1
hexokinase 1
chr16_-_76022266 1.02 ENSMUST00000114240.1
SAM domain, SH3 domain and nuclear localization signals, 1
chr11_+_67277124 1.01 ENSMUST00000019625.5
myosin, heavy polypeptide 8, skeletal muscle, perinatal
chr7_-_45092198 1.01 ENSMUST00000140449.1
ENSMUST00000117546.1
ENSMUST00000019683.3
reticulocalbin 3, EF-hand calcium binding domain
chr5_-_38876693 0.97 ENSMUST00000169819.1
ENSMUST00000171633.1
cytokine-dependent hematopoietic cell linker
chr9_-_95750335 0.96 ENSMUST00000053785.3
transient receptor potential cation channel, subfamily C, member 1
chr15_+_85017138 0.96 ENSMUST00000023070.5
uroplakin 3A
chr5_+_13399309 0.96 ENSMUST00000030714.7
ENSMUST00000141968.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr8_-_94876269 0.90 ENSMUST00000046461.7
docking protein 4
chr19_+_3323301 0.87 ENSMUST00000025835.4
carnitine palmitoyltransferase 1a, liver
chr9_+_27030159 0.87 ENSMUST00000073127.7
ENSMUST00000086198.4
non-SMC condensin II complex, subunit D3
chr12_-_118198917 0.86 ENSMUST00000084806.6
dynein, axonemal, heavy chain 11
chr9_+_108991902 0.85 ENSMUST00000147989.1
ENSMUST00000051873.8
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr12_-_115964196 0.85 ENSMUST00000103550.2
immunoglobulin heavy variable 1-83
chr8_+_45885479 0.85 ENSMUST00000034053.5
PDZ and LIM domain 3
chr16_+_32186192 0.84 ENSMUST00000099990.3
brain expressed gene 6
chr1_+_74791516 0.83 ENSMUST00000006718.8
wingless related MMTV integration site 10a
chr11_-_120598346 0.83 ENSMUST00000026125.2
Aly/REF export factor
chr17_+_37002510 0.83 ENSMUST00000069250.7
zinc finger protein 57
chr2_-_101883010 0.83 ENSMUST00000154525.1
proline rich 5 like
chr18_-_70141568 0.82 ENSMUST00000121693.1
RAB27b, member RAS oncogene family
chr3_+_28781305 0.82 ENSMUST00000060500.7
eukaryotic translation initiation factor 5A2
chr10_-_62379852 0.81 ENSMUST00000143236.1
ENSMUST00000133429.1
ENSMUST00000132926.1
ENSMUST00000116238.2
hexokinase 1
chr12_+_55124528 0.80 ENSMUST00000177768.1
family with sequence similarity 177, member A
chr7_-_45092130 0.80 ENSMUST00000148175.1
reticulocalbin 3, EF-hand calcium binding domain
chr6_-_136922169 0.79 ENSMUST00000032343.6
endoplasmic reticulum protein 27
chr1_+_178187721 0.75 ENSMUST00000159284.1
desumoylating isopeptidase 2
chrX_+_164140447 0.74 ENSMUST00000073973.4
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr13_+_21811737 0.73 ENSMUST00000104941.2
histone cluster 1, H4m
chr5_-_5694559 0.72 ENSMUST00000115426.2
six transmembrane epithelial antigen of prostate 2
chr17_+_35821675 0.72 ENSMUST00000003635.6
immediate early response 3
chr1_-_149922339 0.72 ENSMUST00000111926.2
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr8_-_105707933 0.71 ENSMUST00000013299.9
enkurin domain containing 1
chr3_-_59344256 0.71 ENSMUST00000039419.6
immunoglobulin superfamily, member 10
chr7_+_30787897 0.71 ENSMUST00000098559.1
keratinocyte differentiation associated protein
chr19_-_7711263 0.69 ENSMUST00000025666.7
solute carrier family 22 (organic anion transporter), member 19
chrX_+_153139941 0.68 ENSMUST00000039720.4
ENSMUST00000144175.2
Ras-related GTP binding B
chr17_-_28441718 0.67 ENSMUST00000153744.1
FK506 binding protein 5
chr10_-_127341583 0.67 ENSMUST00000026474.3
GLI-Kruppel family member GLI1
chr17_-_10320229 0.66 ENSMUST00000053066.6
quaking
chr15_+_80133114 0.66 ENSMUST00000023050.7
TGF-beta activated kinase 1/MAP3K7 binding protein 1
chr3_+_103860265 0.66 ENSMUST00000029433.7
protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr19_-_43752924 0.66 ENSMUST00000045562.5
cytochrome c oxidase assembly protein 15
chr2_+_28496891 0.66 ENSMUST00000163121.1
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1
chr2_+_152626932 0.65 ENSMUST00000000369.3
ENSMUST00000150913.1
rad and gem related GTP binding protein 1
chr5_-_74068361 0.62 ENSMUST00000119154.1
ENSMUST00000068058.7
ubiquitin specific peptidase 46
chr9_-_60687459 0.60 ENSMUST00000114032.1
ENSMUST00000166168.1
ENSMUST00000132366.1
leucine rich repeat containing 49
chr18_+_65581704 0.59 ENSMUST00000182979.1
zinc finger protein 532
chr16_+_17208135 0.59 ENSMUST00000169803.1
RIMS binding protein 3
chr5_-_140649018 0.58 ENSMUST00000042661.3
tweety homolog 3 (Drosophila)
chr5_+_143651222 0.58 ENSMUST00000110727.1
cytohesin 3
chr9_-_107635330 0.58 ENSMUST00000055704.6
guanine nucleotide binding protein (G protein), alpha inhibiting 2
chr3_-_19628669 0.58 ENSMUST00000119133.1
RIKEN cDNA 1700064H15 gene
chr19_+_53140430 0.57 ENSMUST00000111741.2
adducin 3 (gamma)
chr13_-_112580662 0.57 ENSMUST00000051756.6
interleukin 31 receptor A
chr10_+_80930071 0.57 ENSMUST00000015456.8
growth arrest and DNA-damage-inducible 45 beta
chr16_+_23290464 0.57 ENSMUST00000115335.1
beta galactoside alpha 2,6 sialyltransferase 1
chrX_+_52791179 0.56 ENSMUST00000101588.1
coiled-coil domain containing 160
chr5_-_92278155 0.56 ENSMUST00000159345.1
ENSMUST00000113102.3
N-acylethanolamine acid amidase
chr6_+_123229843 0.56 ENSMUST00000112554.2
ENSMUST00000024118.4
ENSMUST00000117130.1
C-type lectin domain family 4, member n
chr11_+_3514861 0.54 ENSMUST00000094469.4
selenoprotein M
chr11_+_96464649 0.54 ENSMUST00000107663.3
src family associated phosphoprotein 1
chr2_+_24385313 0.54 ENSMUST00000056641.8
pleckstrin and Sec7 domain containing 4
chr11_-_116412965 0.54 ENSMUST00000100202.3
ENSMUST00000106398.2
ring finger protein 157
chr4_+_12906838 0.54 ENSMUST00000143186.1
ENSMUST00000183345.1
triple QxxK/R motif containing
chr1_-_152625212 0.53 ENSMUST00000027760.7
ral guanine nucleotide dissociation stimulator,-like 1
chr6_+_86404257 0.53 ENSMUST00000095752.2
ENSMUST00000130967.1
cytotoxic granule-associated RNA binding protein 1
chr16_-_63864114 0.52 ENSMUST00000064405.6
Eph receptor A3
chr7_+_88430257 0.50 ENSMUST00000107256.2
RAB38, member of RAS oncogene family
chr10_+_70204675 0.50 ENSMUST00000020090.1
RIKEN cDNA 2310015B20 gene
chr8_+_21055047 0.50 ENSMUST00000098899.3
defensin, alpha, 23
chr4_+_155790439 0.50 ENSMUST00000165000.1
ankyrin repeat domain 65
chr6_+_122921805 0.50 ENSMUST00000060484.8
C-type lectin domain family 4, member a1
chr7_-_133123770 0.49 ENSMUST00000164896.1
ENSMUST00000171968.1
C-terminal binding protein 2
chr7_-_46795661 0.49 ENSMUST00000123725.1
Hermansky-Pudlak syndrome 5 homolog (human)
chr1_-_155232710 0.49 ENSMUST00000035914.3
cDNA sequence BC034090
chr11_-_75439551 0.48 ENSMUST00000128330.1
serine (or cysteine) peptidase inhibitor, clade F, member 2
chr17_+_25016068 0.48 ENSMUST00000137386.1
intraflagellar transport 140
chr14_+_32833955 0.48 ENSMUST00000104926.2
family with sequence similarity 170, member B
chr5_+_117120120 0.48 ENSMUST00000111978.1
TAO kinase 3
chr7_-_44986313 0.48 ENSMUST00000045325.6
ENSMUST00000085387.4
ENSMUST00000107840.1
ENSMUST00000107843.3
ENSMUST00000107842.3
protein arginine N-methyltransferase 1
chr4_+_48585193 0.47 ENSMUST00000107703.1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr19_-_53371766 0.47 ENSMUST00000086887.1
predicted gene 10197
chr17_+_87635974 0.47 ENSMUST00000053577.8
epithelial cell adhesion molecule
chr2_+_125247190 0.46 ENSMUST00000082122.7
deoxyuridine triphosphatase
chr11_+_60140066 0.46 ENSMUST00000171108.1
ENSMUST00000090806.4
retinoic acid induced 1
chr6_+_86404219 0.46 ENSMUST00000095754.3
ENSMUST00000095753.2
cytotoxic granule-associated RNA binding protein 1
chr19_-_6128208 0.46 ENSMUST00000025702.7
sorting nexin 15
chr6_+_86404336 0.45 ENSMUST00000113713.2
ENSMUST00000113708.1
cytotoxic granule-associated RNA binding protein 1
chr12_+_85599047 0.45 ENSMUST00000177587.1
Jun dimerization protein 2
chr19_-_5366285 0.44 ENSMUST00000170010.1
barrier to autointegration factor 1
chr4_+_84884418 0.43 ENSMUST00000169371.2
centlein, centrosomal protein
chr7_-_140082246 0.43 ENSMUST00000166758.2
calcyon neuron-specific vesicular protein
chr9_+_45370185 0.42 ENSMUST00000085939.6
FXYD domain-containing ion transport regulator 6
chr14_+_56402656 0.42 ENSMUST00000095793.1
ring finger protein 17
chr7_-_4532419 0.41 ENSMUST00000094897.4
dynein, axonemal assembly factor 3
chr7_-_119479249 0.41 ENSMUST00000033263.4
uromodulin
chr19_+_29951808 0.41 ENSMUST00000136850.1
interleukin 33
chr10_-_87008015 0.41 ENSMUST00000035288.8
stabilin 2
chrX_-_102189371 0.41 ENSMUST00000033683.7
ribosomal protein S4, X-linked
chr10_+_80855275 0.40 ENSMUST00000035597.8
signal peptide peptidase like 2B
chr1_-_87101590 0.40 ENSMUST00000113270.2
alkaline phosphatase, intestinal
chr1_+_178187417 0.40 ENSMUST00000161075.1
ENSMUST00000027783.7
desumoylating isopeptidase 2
chr12_+_79130777 0.40 ENSMUST00000021550.6
arginase type II
chr19_-_6128144 0.39 ENSMUST00000154601.1
ENSMUST00000138931.1
sorting nexin 15
chr19_+_5024006 0.38 ENSMUST00000025826.5
solute carrier family 29 (nucleoside transporters), member 2
chr12_-_80260356 0.36 ENSMUST00000021554.8
actinin, alpha 1
chr6_-_69400097 0.36 ENSMUST00000177795.1
immunoglobulin kappa variable 4-62
chr4_-_108406676 0.36 ENSMUST00000184609.1
glutathione peroxidase 7
chr11_-_8973266 0.35 ENSMUST00000154153.1
polycystic kidney disease 1 like 1
chr13_+_12395362 0.35 ENSMUST00000059270.8
HEAT repeat containing 1
chr12_+_81631369 0.35 ENSMUST00000036116.5
tetratricopeptide repeat domain 9
chr4_+_11558914 0.34 ENSMUST00000178703.1
ENSMUST00000095145.5
ENSMUST00000108306.2
ENSMUST00000070755.6
RAD54 homolog B (S. cerevisiae)
chr18_+_69925466 0.34 ENSMUST00000043929.4
coiled-coil domain containing 68
chrX_+_6873484 0.34 ENSMUST00000145302.1
diacylglycerol kinase kappa
chr6_-_34977999 0.33 ENSMUST00000044387.7
RIKEN cDNA 2010107G12 gene
chr3_+_138352378 0.33 ENSMUST00000090166.4
alcohol dehydrogenase 6B (class V)
chr15_+_82252397 0.33 ENSMUST00000136948.1
RIKEN cDNA 1500009C09 gene
chr6_-_66559708 0.33 ENSMUST00000079584.1
vomeronasal 1 receptor 32
chr5_-_149053038 0.33 ENSMUST00000085546.6
high mobility group box 1
chr17_-_35164891 0.32 ENSMUST00000025253.5
proline-rich coiled-coil 2A
chr11_+_115475645 0.32 ENSMUST00000035240.6
armadillo repeat containing 7
chr11_-_40733373 0.31 ENSMUST00000020579.8
hyaluronan mediated motility receptor (RHAMM)
chr1_-_126738167 0.31 ENSMUST00000160693.1
NCK-associated protein 5
chr18_-_60848911 0.31 ENSMUST00000177172.1
ENSMUST00000175934.1
ENSMUST00000176630.1
Treacher Collins Franceschetti syndrome 1, homolog
chr1_+_85575676 0.31 ENSMUST00000178024.1
RIKEN cDNA G530012D1 gene
chr9_+_44334685 0.30 ENSMUST00000052686.2
H2A histone family, member X
chr2_+_30077684 0.30 ENSMUST00000125346.1
protein kinase N3
chr2_+_144033059 0.30 ENSMUST00000037722.2
ENSMUST00000110032.1
barrier to autointegration factor 2
chr19_+_43752996 0.30 ENSMUST00000026199.7
ENSMUST00000112047.3
ENSMUST00000153295.1
cutC copper transporter homolog (E.coli)
chr5_-_92310003 0.30 ENSMUST00000031364.1
SDA1 domain containing 1
chr5_+_48242549 0.30 ENSMUST00000172493.1
slit homolog 2 (Drosophila)
chr14_-_105177280 0.29 ENSMUST00000100327.3
ENSMUST00000022715.7
RNA binding motif protein 26
chr11_+_101246960 0.29 ENSMUST00000107282.3
receptor (calcitonin) activity modifying protein 2
chr12_-_111980751 0.28 ENSMUST00000170525.1
cDNA sequence BC048943
chr1_+_74153981 0.28 ENSMUST00000027372.7
ENSMUST00000106899.2
chemokine (C-X-C motif) receptor 2
chr11_-_116694802 0.28 ENSMUST00000079545.5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
chr18_+_42511496 0.28 ENSMUST00000025375.7
transcription elongation regulator 1 (CA150)
chr5_-_137613759 0.28 ENSMUST00000155251.1
ENSMUST00000124693.1
procollagen C-endopeptidase enhancer protein
chr11_-_69837781 0.28 ENSMUST00000108634.2
neuroligin 2
chr11_+_70505244 0.28 ENSMUST00000019063.2
transmembrane 4 superfamily member 5
chr3_+_87796938 0.28 ENSMUST00000029711.2
ENSMUST00000107582.2
insulin receptor-related receptor
chr4_-_141053660 0.28 ENSMUST00000040222.7
ciliary rootlet coiled-coil, rootletin
chr2_+_91922178 0.27 ENSMUST00000170432.1
cholinergic receptor, muscarinic 4
chr17_+_29032664 0.27 ENSMUST00000130216.1
serine/arginine-rich splicing factor 3
chr11_-_86257553 0.27 ENSMUST00000132024.1
ENSMUST00000139285.1
integrator complex subunit 2
chrX_-_139714481 0.27 ENSMUST00000183728.1
predicted gene 15013
chr5_+_12383156 0.27 ENSMUST00000030868.6
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr2_+_181680284 0.26 ENSMUST00000103042.3
transcription elongation factor A (SII), 2
chr4_+_84884276 0.26 ENSMUST00000047023.6
centlein, centrosomal protein

Network of associatons between targets according to the STRING database.

First level regulatory network of Crx_Gsc

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0009753 sesquiterpenoid metabolic process(GO:0006714) response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.7 0.7 GO:0070433 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
0.6 4.5 GO:0015671 oxygen transport(GO:0015671)
0.4 2.6 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.4 1.2 GO:0070315 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718) G1 to G0 transition involved in cell differentiation(GO:0070315)
0.4 2.0 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.4 1.9 GO:0010920 negative regulation of inositol phosphate biosynthetic process(GO:0010920) protein secretion by platelet(GO:0070560)
0.4 3.5 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.3 3.3 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.3 5.0 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.3 3.6 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.3 2.3 GO:0030916 otic vesicle formation(GO:0030916)
0.2 1.9 GO:0006735 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.2 3.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.2 1.0 GO:1903375 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.2 1.1 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256) tetrahydrofolate biosynthetic process(GO:0046654)
0.2 0.7 GO:0015801 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.2 1.7 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.2 0.5 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.2 0.5 GO:0019043 establishment of viral latency(GO:0019043)
0.2 2.9 GO:0032096 negative regulation of response to food(GO:0032096)
0.2 2.4 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.2 0.9 GO:0097503 sialylation(GO:0097503)
0.2 3.4 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.2 0.7 GO:0060032 notochord regression(GO:0060032)
0.2 0.7 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 1.0 GO:0060157 urinary bladder development(GO:0060157)
0.2 0.5 GO:0006226 dUMP biosynthetic process(GO:0006226)
0.1 0.9 GO:0003356 regulation of cilium beat frequency(GO:0003356)
0.1 1.5 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.1 0.3 GO:0010446 response to alkaline pH(GO:0010446)
0.1 0.8 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.8 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.5 GO:0060155 platelet dense granule organization(GO:0060155)
0.1 0.5 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 0.7 GO:2001280 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.4 GO:0009726 detection of nodal flow(GO:0003127) detection of endogenous stimulus(GO:0009726)
0.1 0.5 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.3 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)
0.1 0.9 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.1 0.4 GO:0072236 metanephric loop of Henle development(GO:0072236)
0.1 0.7 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.1 0.4 GO:0043091 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.1 0.7 GO:0002238 response to molecule of fungal origin(GO:0002238)
0.1 0.3 GO:0050929 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.1 0.5 GO:0080154 regulation of fertilization(GO:0080154)
0.1 1.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.9 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 0.8 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.3 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 1.0 GO:0046541 saliva secretion(GO:0046541)
0.1 0.2 GO:0072034 renal vesicle induction(GO:0072034)
0.1 0.3 GO:0002353 plasma kallikrein-kinin cascade(GO:0002353)
0.1 0.4 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.1 1.7 GO:0033574 response to testosterone(GO:0033574)
0.1 0.7 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 0.6 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.1 0.2 GO:0002644 negative regulation of tolerance induction(GO:0002644)
0.1 0.3 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.1 0.6 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.3 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 0.6 GO:0008343 adult feeding behavior(GO:0008343)
0.1 0.2 GO:0072554 Notch signaling pathway involved in heart induction(GO:0003137) regulation of Notch signaling pathway involved in heart induction(GO:0035480) positive regulation of Notch signaling pathway involved in heart induction(GO:0035481) arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel lumenization(GO:0072554) blood vessel endothelial cell fate specification(GO:0097101) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.1 0.2 GO:0061289 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.1 0.7 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.1 0.2 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.1 0.5 GO:0003072 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) negative regulation of plasminogen activation(GO:0010757)
0.1 1.0 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
0.1 0.3 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 0.9 GO:0009437 carnitine metabolic process(GO:0009437) positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 1.0 GO:0030049 muscle filament sliding(GO:0030049)
0.1 0.2 GO:0090273 somatostatin secretion(GO:0070253) regulation of somatostatin secretion(GO:0090273)
0.1 0.3 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.1 0.5 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.7 GO:0030259 lipid glycosylation(GO:0030259)
0.1 0.7 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 1.0 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.1 0.4 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.1 1.3 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.1 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.0 0.2 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.6 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.0 0.8 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.0 1.2 GO:0045953 negative regulation of natural killer cell mediated cytotoxicity(GO:0045953)
0.0 0.7 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.4 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.2 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 1.1 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0032240 RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.0 0.5 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.2 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
0.0 0.5 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.2 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.3 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.7 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.5 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 1.5 GO:0021591 ventricular system development(GO:0021591)
0.0 0.1 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.2 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.4 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.1 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.8 GO:0002820 negative regulation of adaptive immune response(GO:0002820)
0.0 0.2 GO:0048539 bone marrow development(GO:0048539)
0.0 0.2 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.0 0.2 GO:1905146 lysosomal protein catabolic process(GO:1905146)
0.0 0.7 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0071799 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0 0.1 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.5 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.9 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.3 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.4 GO:0015858 nucleoside transport(GO:0015858)
0.0 0.1 GO:0045448 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0 0.3 GO:0042790 transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.0 0.5 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.4 GO:0031065 positive regulation of histone deacetylation(GO:0031065)
0.0 0.2 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.7 GO:0042246 tissue regeneration(GO:0042246)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.1 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.4 GO:0036344 platelet formation(GO:0030220) platelet morphogenesis(GO:0036344)
0.0 0.3 GO:0055070 copper ion homeostasis(GO:0055070)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331) B cell homeostatic proliferation(GO:0002358)
0.0 1.2 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 0.1 GO:2001204 regulation of osteoclast development(GO:2001204)
0.0 0.1 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.0 0.0 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.0 GO:0008594 photoreceptor cell morphogenesis(GO:0008594)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.4 GO:0071173 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.5 GO:0005833 hemoglobin complex(GO:0005833)
0.3 0.9 GO:0000799 nuclear condensin complex(GO:0000799) germinal vesicle(GO:0042585)
0.2 3.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.2 0.8 GO:0032585 multivesicular body membrane(GO:0032585)
0.2 1.4 GO:0097165 nuclear stress granule(GO:0097165)
0.1 2.6 GO:0031143 pseudopodium(GO:0031143)
0.1 0.7 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.4 GO:1990047 spindle matrix(GO:1990047)
0.1 0.5 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 6.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 4.0 GO:0002080 acrosomal membrane(GO:0002080)
0.1 0.6 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 0.4 GO:0032127 dense core granule membrane(GO:0032127)
0.1 0.4 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 1.2 GO:0030061 mitochondrial crista(GO:0030061)
0.1 1.7 GO:0030125 clathrin vesicle coat(GO:0030125)
0.1 0.6 GO:0002177 manchette(GO:0002177)
0.1 0.6 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 0.5 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.5 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.8 GO:0031932 TORC2 complex(GO:0031932)
0.1 0.7 GO:0097542 ciliary tip(GO:0097542)
0.1 1.6 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.5 GO:0034709 methylosome(GO:0034709)
0.0 0.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.3 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 1.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.7 GO:0042599 lamellar body(GO:0042599)
0.0 0.7 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.5 GO:0032039 integrator complex(GO:0032039)
0.0 2.0 GO:0005871 kinesin complex(GO:0005871)
0.0 0.8 GO:0032982 myosin filament(GO:0032982)
0.0 0.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.7 GO:0042588 zymogen granule(GO:0042588)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.5 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.1 GO:0036396 MIS complex(GO:0036396)
0.0 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 4.5 GO:0000793 condensed chromosome(GO:0000793)
0.0 0.3 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.7 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.1 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 1.0 GO:0030315 T-tubule(GO:0030315)
0.0 0.6 GO:0042101 T cell receptor complex(GO:0042101)
0.0 2.4 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.0 GO:0043034 costamere(GO:0043034)
0.0 0.3 GO:0010369 chromocenter(GO:0010369)
0.0 7.0 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.0 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.3 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.1 GO:0045120 pronucleus(GO:0045120)
0.0 0.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.2 GO:0009925 basal plasma membrane(GO:0009925)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.7 GO:0030286 dynein complex(GO:0030286)
0.0 0.1 GO:0005869 dynactin complex(GO:0005869)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 9.0 GO:0004556 alpha-amylase activity(GO:0004556)
1.1 4.5 GO:0031721 hemoglobin alpha binding(GO:0031721)
1.0 3.1 GO:0047787 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.9 2.6 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.6 2.4 GO:0015057 thrombin receptor activity(GO:0015057)
0.3 6.4 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.3 3.5 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.3 1.1 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.3 3.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.3 3.6 GO:0003796 lysozyme activity(GO:0003796)
0.2 1.9 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 3.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 0.9 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.2 0.5 GO:0019959 interleukin-8 binding(GO:0019959)
0.2 0.5 GO:0030519 snoRNP binding(GO:0030519)
0.1 2.9 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 2.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 3.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.3 GO:0000401 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.1 0.7 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.3 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.1 0.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 0.9 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 0.6 GO:0097643 amylin receptor activity(GO:0097643)
0.1 0.7 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.4 GO:0004096 catalase activity(GO:0004096)
0.1 0.5 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.7 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 2.0 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 1.2 GO:0031432 titin binding(GO:0031432)
0.1 1.0 GO:0070679 store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 0.5 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 1.3 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.4 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.5 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.4 GO:0019864 IgG binding(GO:0019864)
0.1 0.4 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 2.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.5 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.1 0.4 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.3 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.7 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 1.7 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.7 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.2 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.0 1.4 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.4 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.2 GO:0050694 galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.8 GO:0031489 myosin V binding(GO:0031489)
0.0 1.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.7 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.8 GO:0000146 microfilament motor activity(GO:0000146)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 2.7 GO:0003777 microtubule motor activity(GO:0003777)
0.0 5.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.7 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.7 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 1.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.0 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 0.6 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.4 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.9 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.3 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.7 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 0.3 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.4 GO:0017080 sodium channel regulator activity(GO:0017080)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 9.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 3.4 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 3.3 PID BARD1 PATHWAY BARD1 signaling events
0.1 2.0 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 1.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 6.3 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.3 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.9 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.6 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.7 PID ENDOTHELIN PATHWAY Endothelins
0.0 3.3 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 3.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.7 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 3.8 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 0.4 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.3 PID FANCONI PATHWAY Fanconi anemia pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.8 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.3 3.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.3 5.9 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 11.7 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.2 0.6 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.2 3.5 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.1 0.7 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.1 0.7 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1 4.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 1.8 REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES Genes involved in Transmission across Chemical Synapses
0.1 0.5 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 1.0 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 2.1 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 1.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.9 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 1.4 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.8 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 2.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 1.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.9 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.1 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 1.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway