GSE58827: Dynamics of the Mouse Liver


Results for AAGGUGC

Z-value: 0.33

Motif logo

miRNA associated with seed AAGGUGC

NamemiRBASE accession

Activity profile of AAGGUGC motif

Sorted Z-values of AAGGUGC motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_76669811 2.07 ENSMUST00000037824.4
forkhead box H1
chr16_-_92826004 1.00 ENSMUST00000023673.7
runt related transcription factor 1
chr16_-_22163299 0.92 ENSMUST00000100052.4
insulin-like growth factor 2 mRNA binding protein 2
chr7_-_116038734 0.84 ENSMUST00000166877.1
SRY-box containing gene 6
chr5_-_73256555 0.74 ENSMUST00000171179.1
furry homolog-like (Drosophila)
furry homolog-like (Drosophila)
chr10_-_78244602 0.74 ENSMUST00000000384.6
trafficking protein particle complex 10
chr1_-_161876656 0.71 ENSMUST00000048377.5
SUN domain containing ossification factor
chr2_+_118111876 0.69 ENSMUST00000039559.8
thrombospondin 1
chrX_+_9199865 0.68 ENSMUST00000069763.2
LanC lantibiotic synthetase component C-like 3 (bacterial)
chr2_-_34913976 0.67 ENSMUST00000028232.3
PHD finger protein 19
chr17_-_29888570 0.57 ENSMUST00000171691.1
MAM domain containing glycosylphosphatidylinositol anchor 1
chr2_+_156420837 0.54 ENSMUST00000103137.3
erythrocyte protein band 4.1-like 1
chr2_+_164074122 0.53 ENSMUST00000018353.7
serine/threonine kinase 4
chr1_+_170644523 0.53 ENSMUST00000046792.8
olfactomedin-like 2B
chr4_-_134018829 0.51 ENSMUST00000051674.2
lin-28 homolog A (C. elegans)
chr1_-_97661950 0.49 ENSMUST00000053033.7
DNA segment, Chr 1, ERATO Doi 622, expressed
chr3_+_105452326 0.44 ENSMUST00000098761.3
potassium voltage-gated channel, Shal-related family, member 3
chr8_-_35495487 0.41 ENSMUST00000033927.6
exoribonuclease 1
chr5_+_96997676 0.41 ENSMUST00000112974.1
BMP2 inducible kinase
chr5_+_75574916 0.40 ENSMUST00000144270.1
kit oncogene
chr8_-_120589304 0.38 ENSMUST00000034278.5
GINS complex subunit 2 (Psf2 homolog)
chr14_+_47472547 0.35 ENSMUST00000168833.1
F-box protein 34
chr19_+_53140430 0.34 ENSMUST00000111741.2
adducin 3 (gamma)
chr15_+_80711292 0.34 ENSMUST00000067689.7
trinucleotide repeat containing 6b
chr15_+_73723131 0.34 ENSMUST00000165541.1
protein tyrosine phosphatase 4a3
chr6_+_119236507 0.33 ENSMUST00000037434.6
calcium channel, voltage-dependent, alpha 2/delta subunit 4
chr13_+_109903089 0.33 ENSMUST00000120664.1
phosphodiesterase 4D, cAMP specific
chr10_+_40349265 0.32 ENSMUST00000044672.4
cyclin-dependent kinase 19
chr1_-_63114516 0.27 ENSMUST00000097718.2
INO80 complex subunit D
chr10_-_53379816 0.26 ENSMUST00000095691.5
centrosomal protein 85-like
chr9_-_14381242 0.25 ENSMUST00000167549.1
endonuclease domain containing 1
chr11_+_29373618 0.24 ENSMUST00000040182.6
coiled coil domain containing 88A
chr15_-_12592556 0.24 ENSMUST00000075317.5
PDZ domain containing 2
chr10_-_19015347 0.22 ENSMUST00000019997.4
tumor necrosis factor, alpha-induced protein 3
chr16_-_78376758 0.21 ENSMUST00000023570.7
B cell translocation gene 3
chr3_-_9610074 0.21 ENSMUST00000041124.7
zinc finger protein 704
chr3_-_30969399 0.21 ENSMUST00000177992.1
polyhomeotic-like 3 (Drosophila)
chr6_+_52713729 0.21 ENSMUST00000080723.4
Tax1 (human T cell leukemia virus type I) binding protein 1
chr1_+_74409376 0.21 ENSMUST00000027366.6
villin 1
chr12_+_52516077 0.20 ENSMUST00000110725.1
Rho GTPase activating protein 5
chr12_-_15816762 0.20 ENSMUST00000020922.7
tribbles homolog 2 (Drosophila)
chr6_-_25690729 0.20 ENSMUST00000054867.6
G protein-coupled receptor 37
chr9_+_121760000 0.19 ENSMUST00000093772.3
zinc finger protein 651
chr3_+_60501252 0.19 ENSMUST00000099087.2
muscleblind-like 1 (Drosophila)
chr19_-_59943647 0.19 ENSMUST00000171986.1
RAB11 family interacting protein 2 (class I)
chr18_+_53472981 0.18 ENSMUST00000115399.1
PR domain containing 6
chr5_+_137518880 0.18 ENSMUST00000031727.7
GRB10 interacting GYF protein 1
chr13_-_111808938 0.17 ENSMUST00000109267.2
mitogen-activated protein kinase kinase kinase 1
chr5_-_69592311 0.16 ENSMUST00000031117.6
glucosamine-6-phosphate deaminase 2
chr13_+_60211933 0.16 ENSMUST00000060705.2
predicted gene 5084
chr8_-_84687839 0.15 ENSMUST00000001975.4
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr13_+_41606216 0.15 ENSMUST00000129449.1
transmembrane protein 170B
chr3_-_59344256 0.14 ENSMUST00000039419.6
immunoglobulin superfamily, member 10
chr16_+_94085226 0.14 ENSMUST00000072182.7
single-minded homolog 2 (Drosophila)
chr5_+_23434435 0.13 ENSMUST00000094962.2
lysine (K)-specific methyltransferase 2E
chr13_-_93499803 0.13 ENSMUST00000065537.7
junction-mediating and regulatory protein
chrX_-_108834303 0.13 ENSMUST00000101283.3
bromodomain and WD repeat domain containing 3
chr4_-_119492563 0.12 ENSMUST00000049994.7
ribosomal modification protein rimK-like family member A
chr13_-_41487306 0.12 ENSMUST00000021794.6
neural precursor cell expressed, developmentally down-regulated gene 9
chr10_+_13552894 0.12 ENSMUST00000019944.8
adenosine deaminase, tRNA-specific 2
chr1_-_170215380 0.12 ENSMUST00000027979.7
U2AF homology motif (UHM) kinase 1
chr11_+_77686155 0.12 ENSMUST00000100802.4
nuclear fragile X mental retardation protein interacting protein 2
chr2_+_65845767 0.11 ENSMUST00000122912.1
cysteine-serine-rich nuclear protein 3
chr11_+_32455362 0.10 ENSMUST00000051053.4
ubiquitin domain containing 2
chr9_-_53536728 0.10 ENSMUST00000118282.1
ataxia telangiectasia mutated homolog (human)
chr13_+_97241096 0.10 ENSMUST00000041623.7
ectodermal-neural cortex 1
chr2_+_19445632 0.08 ENSMUST00000028068.2
pancreas specific transcription factor, 1a
chr7_-_126502380 0.08 ENSMUST00000167759.1
ataxin 2-like
chr16_+_44139821 0.08 ENSMUST00000159514.1
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr2_+_72285637 0.07 ENSMUST00000090824.5
sterile alpha motif and leucine zipper containing kinase AZK
chr1_-_166002591 0.07 ENSMUST00000111429.4
POU domain, class 2, transcription factor 1
chr11_-_116086929 0.07 ENSMUST00000074628.6
WW domain binding protein 2
chr1_+_134560190 0.06 ENSMUST00000112198.1
lysine (K)-specific demethylase 5B
chr12_+_3426857 0.05 ENSMUST00000111215.3
additional sex combs like 2 (Drosophila)
chr10_+_80494835 0.05 ENSMUST00000051773.8
one cut domain, family member 3
chr3_+_96697076 0.04 ENSMUST00000162778.2
protein inhibitor of activated STAT 3
chr13_-_64153194 0.04 ENSMUST00000059817.4
zinc finger protein 367
chr3_-_27896360 0.04 ENSMUST00000058077.3
transmembrane protein 212
chr1_-_161131428 0.03 ENSMUST00000111611.1
kelch-like 20
chr12_+_84875769 0.03 ENSMUST00000171853.1
RIKEN cDNA D030025P21 gene
chr11_-_100738153 0.03 ENSMUST00000155500.1
RAB5C, member RAS oncogene family
chr13_-_48870885 0.02 ENSMUST00000035540.7
PHD finger protein 2
chr16_-_52454074 0.01 ENSMUST00000023312.7
activated leukocyte cell adhesion molecule
chr12_-_91590009 0.01 ENSMUST00000021345.6
general transcription factor II A, 1
chr12_+_12262139 0.01 ENSMUST00000069066.6
family with sequence similarity 49, member A
chr3_+_88142328 0.01 ENSMUST00000001455.6
myocyte enhancer factor 2D
chr1_-_135585314 0.00 ENSMUST00000040599.8
neuron navigator 1
chr8_-_94601720 0.00 ENSMUST00000034226.6
family with sequence similarity 192, member A

Network of associatons between targets according to the STRING database.

First level regulatory network of AAGGUGC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.3 1.0 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
0.2 0.7 GO:0010752 negative regulation of nitric oxide mediated signal transduction(GO:0010751) regulation of cGMP-mediated signaling(GO:0010752)
0.1 0.5 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.7 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.1 0.4 GO:0038109 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.1 0.6 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.1 0.8 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1 0.2 GO:0002631 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573)
0.1 0.7 GO:0090527 actin filament reorganization(GO:0090527)
0.1 0.7 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.2 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.4 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.5 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.2 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.2 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.5 GO:0010764 negative regulation of fibroblast migration(GO:0010764) negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.0 0.4 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.0 0.4 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.0 0.1 GO:0072434 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.3 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.3 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.3 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.2 GO:0045915 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0 0.6 GO:0010714 positive regulation of collagen metabolic process(GO:0010714) positive regulation of collagen biosynthetic process(GO:0032967) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.0 0.2 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.1 GO:0035938 estradiol secretion(GO:0035938) regulation of estradiol secretion(GO:2000864)
0.0 0.3 GO:0050908 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.4 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.9 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 0.4 GO:0000811 GINS complex(GO:0000811)
0.1 0.7 GO:0005577 fibrinogen complex(GO:0005577)
0.1 0.4 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.7 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.4 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.5 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0070052 collagen V binding(GO:0070052)
0.1 0.4 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.1 0.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 1.9 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.4 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.5 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.9 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.2 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 1.0 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.4 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.2 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.7 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.3 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.3 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling