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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for ZNF148
Z-value: 0.91
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Transcription factors associated with ZNF148
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ZNF148 | hg19_v2_chr3_-_125094093_125094198 | 0.51 | 3.0e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr20_+_10199566 Show fit | 0.38 |
ENST00000430336.1
|
synaptosomal-associated protein, 25kDa |
|
| chr19_+_10197463 Show fit | 0.36 |
ENST00000590378.1
ENST00000397881.3 |
chromosome 19 open reading frame 66 |
|
| chr3_-_49203744 Show fit | 0.36 |
ENST00000321895.6
|
coiled-coil domain containing 71 |
|
| chr11_+_46402297 Show fit | 0.36 |
ENST00000405308.2
|
midkine (neurite growth-promoting factor 2) |
|
| chr11_+_46402482 Show fit | 0.34 |
ENST00000441869.1
|
midkine (neurite growth-promoting factor 2) |
|
| chr5_+_172484377 Show fit | 0.34 |
ENST00000523161.1
|
CREB3 regulatory factor |
|
| chr17_+_41177220 Show fit | 0.33 |
ENST00000587250.2
ENST00000544533.1 |
Rho family GTPase 2 |
|
| chr19_-_53662257 Show fit | 0.33 |
ENST00000599096.1
ENST00000334197.7 ENST00000597183.1 ENST00000601804.1 ENST00000601469.2 ENST00000452676.2 |
zinc finger protein 347 |
|
| chr10_-_77161004 Show fit | 0.32 |
ENST00000418818.2
|
RP11-399K21.11 |
|
| chr14_-_24733444 Show fit | 0.30 |
ENST00000560478.1
ENST00000560443.1 |
transglutaminase 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of ZNF148
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.0 | GO:0030421 | defecation(GO:0030421) |
| 0.0 | 0.8 | GO:0043486 | histone exchange(GO:0043486) |
| 0.2 | 0.6 | GO:1990926 | short-term synaptic potentiation(GO:1990926) |
| 0.0 | 0.5 | GO:0060744 | thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744) |
| 0.1 | 0.3 | GO:0009386 | translational attenuation(GO:0009386) |
| 0.1 | 0.3 | GO:0014886 | transition between slow and fast fiber(GO:0014886) |
| 0.1 | 0.3 | GO:0038161 | prolactin signaling pathway(GO:0038161) |
| 0.0 | 0.3 | GO:0043163 | cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229) |
| 0.0 | 0.3 | GO:0061143 | alveolar primary septum development(GO:0061143) |
| 0.0 | 0.3 | GO:0035290 | trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.1 | 0.6 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) |
| 0.0 | 0.4 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 0.0 | 0.4 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.0 | 0.3 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.0 | 0.2 | GO:0031501 | mannosyltransferase complex(GO:0031501) |
| 0.0 | 0.2 | GO:0005956 | protein kinase CK2 complex(GO:0005956) |
| 0.0 | 0.2 | GO:0030896 | checkpoint clamp complex(GO:0030896) |
| 0.0 | 0.2 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.0 | 0.2 | GO:0001520 | outer dense fiber(GO:0001520) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | GO:0019212 | phosphatase inhibitor activity(GO:0019212) |
| 0.0 | 0.6 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.0 | 0.5 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 0.0 | 0.4 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.0 | 0.4 | GO:0070003 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.0 | 0.3 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.0 | 0.3 | GO:0035198 | miRNA binding(GO:0035198) |
| 0.1 | 0.2 | GO:0051908 | double-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0051908) |
| 0.1 | 0.2 | GO:1904599 | advanced glycation end-product binding(GO:1904599) |
| 0.1 | 0.2 | GO:0004584 | dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.9 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.0 | 0.5 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.0 | 0.4 | ST STAT3 PATHWAY | STAT3 Pathway |
| 0.0 | 0.2 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.0 | 0.1 | ST IL 13 PATHWAY | Interleukin 13 (IL-13) Pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
| 0.0 | 0.4 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.0 | 0.4 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.0 | 0.4 | REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI | Genes involved in RIP-mediated NFkB activation via DAI |
| 0.0 | 0.3 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.0 | 0.3 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.0 | 0.2 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |