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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for ZKSCAN1
Z-value: 0.99
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Transcription factors associated with ZKSCAN1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ZKSCAN1 | hg19_v2_chr7_+_99613195_99613206 | -0.31 | 5.6e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr16_+_4364762 Show fit | 1.17 |
ENST00000262366.3
|
GLIS family zinc finger 2 |
|
| chr15_-_78112553 Show fit | 0.75 |
ENST00000562933.1
|
leucine rich repeat and Ig domain containing 1 |
|
| chr17_+_16945820 Show fit | 0.63 |
ENST00000577514.1
|
myosin phosphatase Rho interacting protein |
|
| chr17_-_26220366 Show fit | 0.60 |
ENST00000460380.2
ENST00000508862.1 ENST00000379102.3 ENST00000582441.1 |
LYR motif containing 9 Uncharacterized protein |
|
| chr11_-_72070206 Show fit | 0.48 |
ENST00000544382.1
|
ClpB caseinolytic peptidase B homolog (E. coli) |
|
| chr2_-_65659762 Show fit | 0.48 |
ENST00000440972.1
|
sprouty-related, EVH1 domain containing 2 |
|
| chr17_-_46716647 Show fit | 0.46 |
ENST00000608940.1
|
RP11-357H14.17 |
|
| chr16_-_4665023 Show fit | 0.41 |
ENST00000591897.1
|
UBA-like domain containing 1 |
|
| chr17_+_36858694 Show fit | 0.38 |
ENST00000563897.1
|
CTB-58E17.1 |
|
| chr5_+_127039075 Show fit | 0.38 |
ENST00000514853.2
|
CTC-228N24.1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of ZKSCAN1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.2 | GO:0060994 | regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994) |
| 0.0 | 0.6 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
| 0.2 | 0.5 | GO:1902396 | protein localization to bicellular tight junction(GO:1902396) |
| 0.0 | 0.5 | GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) |
| 0.1 | 0.4 | GO:1904815 | negative regulation of protein localization to chromosome, telomeric region(GO:1904815) |
| 0.1 | 0.4 | GO:0098886 | modification of dendritic spine(GO:0098886) |
| 0.0 | 0.4 | GO:0046339 | diacylglycerol metabolic process(GO:0046339) |
| 0.1 | 0.3 | GO:0006419 | alanyl-tRNA aminoacylation(GO:0006419) |
| 0.1 | 0.3 | GO:1902630 | regulation of membrane hyperpolarization(GO:1902630) |
| 0.1 | 0.3 | GO:0097010 | eukaryotic translation initiation factor 4F complex assembly(GO:0097010) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.0 | 0.5 | GO:0005849 | mRNA cleavage factor complex(GO:0005849) |
| 0.1 | 0.4 | GO:0097444 | spine apparatus(GO:0097444) |
| 0.1 | 0.4 | GO:0001740 | Barr body(GO:0001740) |
| 0.0 | 0.3 | GO:0070765 | gamma-secretase complex(GO:0070765) |
| 0.0 | 0.3 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.0 | 0.3 | GO:0005861 | troponin complex(GO:0005861) |
| 0.0 | 0.2 | GO:0042824 | MHC class I peptide loading complex(GO:0042824) |
| 0.0 | 0.2 | GO:0008540 | proteasome regulatory particle, base subcomplex(GO:0008540) |
| 0.0 | 0.2 | GO:0097342 | ripoptosome(GO:0097342) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.6 | GO:0045029 | UDP-activated nucleotide receptor activity(GO:0045029) |
| 0.1 | 0.5 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 0.0 | 0.4 | GO:0010385 | double-stranded methylated DNA binding(GO:0010385) |
| 0.0 | 0.4 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.0 | 0.4 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.1 | 0.3 | GO:0052895 | norspermine:oxygen oxidoreductase activity(GO:0052894) N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity(GO:0052895) |
| 0.1 | 0.3 | GO:0004813 | alanine-tRNA ligase activity(GO:0004813) |
| 0.1 | 0.3 | GO:0016992 | lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283) |
| 0.1 | 0.3 | GO:0034057 | RNA strand-exchange activity(GO:0034057) |
| 0.0 | 0.3 | GO:0031014 | troponin T binding(GO:0031014) |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
| 0.0 | 0.5 | REACTOME PROCESSING OF INTRONLESS PRE MRNAS | Genes involved in Processing of Intronless Pre-mRNAs |
| 0.0 | 0.5 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.0 | 0.5 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.0 | 0.4 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.0 | 0.3 | REACTOME REGULATED PROTEOLYSIS OF P75NTR | Genes involved in Regulated proteolysis of p75NTR |
| 0.0 | 0.3 | REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY | Genes involved in Adenylate cyclase activating pathway |
| 0.0 | 0.3 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 0.0 | 0.3 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.0 | 0.2 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |