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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ZIC1

Z-value: 0.90

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Transcription factors associated with ZIC1

Gene Symbol Gene ID Gene Info
ZIC1
ENSG00000152977.5 Zic family member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ZIC1hg19_v2_chr3_+_147127142_147127171-0.731.0e-01Click!

Activity profile of ZIC1 motif

Sorted Z-values of ZIC1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_42931567 0.70 ENST00000244289.4
LIPE
lipase, hormone-sensitive
chr1_+_46668994 0.62 ENST00000371980.3
LURAP1
leucine rich adaptor protein 1
chrX_+_70364667 0.56 ENST00000536169.1
ENST00000395855.2
ENST00000374051.3
ENST00000358741.3
NLGN3
neuroligin 3
chr12_-_11036844 0.53 ENST00000428168.2
PRH1
proline-rich protein HaeIII subfamily 1
chr13_-_30160925 0.50 ENST00000450494.1
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr4_+_2626988 0.48 ENST00000509050.1
FAM193A
family with sequence similarity 193, member A
chr17_-_3794021 0.48 ENST00000381769.2
CAMKK1
calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr16_-_31100284 0.47 ENST00000280606.6
PRSS53
protease, serine, 53
chr12_-_11002063 0.46 ENST00000544994.1
ENST00000228811.4
ENST00000540107.1
PRR4
proline rich 4 (lacrimal)
chr11_-_57417405 0.46 ENST00000524669.1
ENST00000300022.3
YPEL4
yippee-like 4 (Drosophila)
chr13_-_45048386 0.45 ENST00000472477.1
TSC22D1
TSC22 domain family, member 1
chr16_+_771663 0.44 ENST00000568916.1
FAM173A
family with sequence similarity 173, member A
chr22_+_29702572 0.42 ENST00000407647.2
ENST00000416823.1
ENST00000428622.1
GAS2L1
growth arrest-specific 2 like 1
chr1_+_1567474 0.42 ENST00000356026.5
MMP23B
matrix metallopeptidase 23B
chr22_-_23922410 0.40 ENST00000249053.3
IGLL1
immunoglobulin lambda-like polypeptide 1
chr19_+_39647271 0.39 ENST00000599657.1
PAK4
p21 protein (Cdc42/Rac)-activated kinase 4
chr19_+_50169081 0.38 ENST00000246784.3
BCL2L12
BCL2-like 12 (proline rich)
chr11_+_208773 0.38 ENST00000528357.1
RIC8A
RIC8 guanine nucleotide exchange factor A
chr22_+_46972975 0.37 ENST00000431155.1
GRAMD4
GRAM domain containing 4
chrX_+_53078465 0.37 ENST00000375466.2
GPR173
G protein-coupled receptor 173
chr18_+_11752783 0.36 ENST00000585642.1
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr11_+_67777751 0.36 ENST00000316367.6
ENST00000007633.8
ENST00000342456.6
ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr12_-_25801478 0.36 ENST00000540106.1
ENST00000445693.1
ENST00000545543.1
ENST00000542224.1
IFLTD1
intermediate filament tail domain containing 1
chr17_-_67057047 0.35 ENST00000495634.1
ENST00000453985.2
ENST00000585714.1
ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr1_-_1711508 0.34 ENST00000378625.1
NADK
NAD kinase
chr17_-_18945798 0.33 ENST00000395635.1
GRAP
GRB2-related adaptor protein
chr22_-_23922448 0.33 ENST00000438703.1
ENST00000330377.2
IGLL1
immunoglobulin lambda-like polypeptide 1
chr14_+_23340822 0.33 ENST00000359591.4
LRP10
low density lipoprotein receptor-related protein 10
chr17_+_16945820 0.33 ENST00000577514.1
MPRIP
myosin phosphatase Rho interacting protein
chr19_+_55987998 0.32 ENST00000591164.1
ZNF628
zinc finger protein 628
chr12_-_59314246 0.30 ENST00000320743.3
LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr11_+_15095108 0.30 ENST00000324229.6
ENST00000533448.1
CALCB
calcitonin-related polypeptide beta
chr17_+_75450099 0.30 ENST00000586433.1
SEPT9
septin 9
chr1_+_17559776 0.30 ENST00000537499.1
ENST00000413717.2
ENST00000536552.1
PADI1
peptidyl arginine deiminase, type I
chr17_+_75450146 0.30 ENST00000585929.1
ENST00000590917.1
SEPT9
septin 9
chr11_+_66824346 0.29 ENST00000532559.1
RHOD
ras homolog family member D
chr15_-_78112553 0.29 ENST00000562933.1
LINGO1
leucine rich repeat and Ig domain containing 1
chr17_+_5981270 0.29 ENST00000571973.1
WSCD1
WSC domain containing 1
chr17_+_40458130 0.28 ENST00000587646.1
STAT5A
signal transducer and activator of transcription 5A
chr9_-_139357413 0.28 ENST00000277537.6
SEC16A
SEC16 homolog A (S. cerevisiae)
chr1_-_20446020 0.28 ENST00000375105.3
PLA2G2D
phospholipase A2, group IID
chr18_+_11752040 0.27 ENST00000423027.3
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr11_+_66824276 0.27 ENST00000308831.2
RHOD
ras homolog family member D
chrX_+_52926322 0.27 ENST00000430150.2
ENST00000452021.2
ENST00000412319.1
FAM156B
family with sequence similarity 156, member B
chr16_+_2255841 0.26 ENST00000301725.7
MLST8
MTOR associated protein, LST8 homolog (S. cerevisiae)
chr5_+_150406527 0.26 ENST00000520059.1
GPX3
glutathione peroxidase 3 (plasma)
chr3_+_71803201 0.26 ENST00000304411.2
GPR27
G protein-coupled receptor 27
chr17_+_75450075 0.26 ENST00000592951.1
SEPT9
septin 9
chr16_-_745946 0.26 ENST00000562563.1
FBXL16
F-box and leucine-rich repeat protein 16
chr9_+_132934835 0.25 ENST00000372398.3
NCS1
neuronal calcium sensor 1
chr22_+_44319619 0.25 ENST00000216180.3
PNPLA3
patatin-like phospholipase domain containing 3
chr2_+_7118755 0.25 ENST00000433456.1
RNF144A
ring finger protein 144A
chr16_+_3185125 0.25 ENST00000576416.1
ZNF213
zinc finger protein 213
chr9_-_123639600 0.24 ENST00000373896.3
PHF19
PHD finger protein 19
chr20_+_61924532 0.24 ENST00000358894.6
ENST00000326996.6
ENST00000435874.1
COL20A1
collagen, type XX, alpha 1
chr2_-_97534312 0.24 ENST00000442264.1
SEMA4C
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr19_-_3028354 0.24 ENST00000586422.1
TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr19_+_34287751 0.24 ENST00000590771.1
ENST00000589786.1
ENST00000284006.6
ENST00000588881.1
KCTD15
potassium channel tetramerization domain containing 15
chr7_+_29874341 0.24 ENST00000409290.1
ENST00000242140.5
WIPF3
WAS/WASL interacting protein family, member 3
chr16_-_4665023 0.23 ENST00000591897.1
UBALD1
UBA-like domain containing 1
chr19_-_2740036 0.23 ENST00000586572.1
ENST00000269740.4
AC006538.4
SLC39A3
Uncharacterized protein
solute carrier family 39 (zinc transporter), member 3
chr9_+_124329336 0.23 ENST00000394340.3
ENST00000436835.1
ENST00000259371.2
DAB2IP
DAB2 interacting protein
chr22_-_24622080 0.23 ENST00000425408.1
GGT5
gamma-glutamyltransferase 5
chr12_-_2966193 0.23 ENST00000382678.3
AC005841.1
Uncharacterized protein ENSP00000372125
chr17_-_3796334 0.23 ENST00000381771.2
ENST00000348335.2
ENST00000158166.5
CAMKK1
calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr8_-_22526597 0.23 ENST00000519513.1
ENST00000276416.6
ENST00000520292.1
ENST00000522268.1
BIN3
bridging integrator 3
chr9_-_79267432 0.23 ENST00000424866.1
PRUNE2
prune homolog 2 (Drosophila)
chr3_-_53080047 0.23 ENST00000482396.1
ENST00000358080.2
ENST00000296295.6
ENST00000394752.3
SFMBT1
Scm-like with four mbt domains 1
chr7_-_128045984 0.22 ENST00000470772.1
ENST00000480861.1
ENST00000496200.1
IMPDH1
IMP (inosine 5'-monophosphate) dehydrogenase 1
chr19_+_42772659 0.22 ENST00000572681.2
CIC
capicua transcriptional repressor
chr10_+_118349920 0.21 ENST00000531984.1
PNLIPRP1
pancreatic lipase-related protein 1
chrX_+_46772065 0.21 ENST00000455411.1
PHF16
jade family PHD finger 3
chr7_-_4877677 0.21 ENST00000538469.1
RADIL
Ras association and DIL domains
chr6_+_90272488 0.21 ENST00000485637.1
ENST00000522705.1
ANKRD6
ankyrin repeat domain 6
chr21_+_18811205 0.21 ENST00000440664.1
C21orf37
chromosome 21 open reading frame 37
chr1_+_44870866 0.21 ENST00000355387.2
ENST00000361799.2
RNF220
ring finger protein 220
chr17_-_5372068 0.21 ENST00000572490.1
DHX33
DEAH (Asp-Glu-Ala-His) box polypeptide 33
chr1_-_111991850 0.21 ENST00000411751.2
WDR77
WD repeat domain 77
chr1_+_1567546 0.20 ENST00000378675.3
MMP23B
matrix metallopeptidase 23B
chr16_+_838614 0.20 ENST00000262315.9
ENST00000455171.2
CHTF18
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
chr7_-_135412925 0.20 ENST00000354042.4
SLC13A4
solute carrier family 13 (sodium/sulfate symporter), member 4
chr2_-_98280383 0.20 ENST00000289228.5
ACTR1B
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr17_-_5372229 0.20 ENST00000433302.3
DHX33
DEAH (Asp-Glu-Ala-His) box polypeptide 33
chr19_-_2739992 0.20 ENST00000545664.1
ENST00000589363.1
ENST00000455372.2
SLC39A3
solute carrier family 39 (zinc transporter), member 3
chr19_+_10563567 0.20 ENST00000344979.3
PDE4A
phosphodiesterase 4A, cAMP-specific
chr15_+_41245160 0.20 ENST00000444189.2
ENST00000446533.3
CHAC1
ChaC, cation transport regulator homolog 1 (E. coli)
chr5_+_140514782 0.19 ENST00000231134.5
PCDHB5
protocadherin beta 5
chr3_-_50329835 0.19 ENST00000429673.2
IFRD2
interferon-related developmental regulator 2
chr11_+_64001962 0.19 ENST00000309422.2
VEGFB
vascular endothelial growth factor B
chr16_-_4664860 0.19 ENST00000587615.1
ENST00000587649.1
ENST00000590965.1
ENST00000591401.1
ENST00000283474.7
UBALD1
UBA-like domain containing 1
chr16_-_2379688 0.19 ENST00000567910.1
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr8_+_25042192 0.18 ENST00000410074.1
DOCK5
dedicator of cytokinesis 5
chr15_+_77713299 0.18 ENST00000559099.1
HMG20A
high mobility group 20A
chr11_+_64002292 0.18 ENST00000426086.2
VEGFB
vascular endothelial growth factor B
chr1_+_62417957 0.18 ENST00000307297.7
ENST00000543708.1
INADL
InaD-like (Drosophila)
chr21_+_45148735 0.18 ENST00000327574.4
PDXK
pyridoxal (pyridoxine, vitamin B6) kinase
chr19_+_42364460 0.17 ENST00000593863.1
RPS19
ribosomal protein S19
chr8_+_21946681 0.17 ENST00000289921.7
FAM160B2
family with sequence similarity 160, member B2
chr3_+_126243126 0.17 ENST00000319340.2
CHST13
carbohydrate (chondroitin 4) sulfotransferase 13
chr6_-_34216766 0.17 ENST00000481533.1
ENST00000468145.1
ENST00000413013.2
ENST00000394990.4
ENST00000335352.3
C6orf1
chromosome 6 open reading frame 1
chr16_+_28858004 0.17 ENST00000322610.8
SH2B1
SH2B adaptor protein 1
chr17_-_61778528 0.17 ENST00000584645.1
LIMD2
LIM domain containing 2
chr17_-_43045439 0.17 ENST00000253407.3
C1QL1
complement component 1, q subcomponent-like 1
chrX_-_129299638 0.17 ENST00000535724.1
ENST00000346424.2
AIFM1
apoptosis-inducing factor, mitochondrion-associated, 1
chr3_+_49027771 0.17 ENST00000475629.1
ENST00000444213.1
P4HTM
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr4_+_2627159 0.16 ENST00000382839.3
ENST00000324666.5
ENST00000545951.1
ENST00000502458.1
ENST00000505311.1
FAM193A
family with sequence similarity 193, member A
chr4_-_40632605 0.16 ENST00000514014.1
RBM47
RNA binding motif protein 47
chr6_+_31540056 0.16 ENST00000418386.2
LTA
lymphotoxin alpha
chr7_-_35734176 0.16 ENST00000413517.1
ENST00000438224.1
HERPUD2
HERPUD family member 2
chr1_+_24120143 0.16 ENST00000374501.1
LYPLA2
lysophospholipase II
chr22_+_44319648 0.15 ENST00000423180.2
PNPLA3
patatin-like phospholipase domain containing 3
chr3_+_42892458 0.15 ENST00000494619.1
ACKR2
atypical chemokine receptor 2
chr9_-_123639445 0.15 ENST00000312189.6
PHF19
PHD finger protein 19
chr6_-_168720425 0.14 ENST00000366796.3
DACT2
dishevelled-binding antagonist of beta-catenin 2
chr10_-_49701686 0.14 ENST00000417247.2
ARHGAP22
Rho GTPase activating protein 22
chr16_+_30953696 0.14 ENST00000566320.2
ENST00000565939.1
FBXL19
F-box and leucine-rich repeat protein 19
chr11_-_73309228 0.14 ENST00000356467.4
ENST00000064778.4
FAM168A
family with sequence similarity 168, member A
chr11_+_63606373 0.13 ENST00000402010.2
ENST00000315032.8
ENST00000377809.4
ENST00000413835.2
ENST00000377810.3
MARK2
MAP/microtubule affinity-regulating kinase 2
chr8_-_144623595 0.13 ENST00000262577.5
ZC3H3
zinc finger CCCH-type containing 3
chrY_+_4868267 0.13 ENST00000333703.4
PCDH11Y
protocadherin 11 Y-linked
chrX_+_2924654 0.13 ENST00000381130.2
ARSH
arylsulfatase family, member H
chr7_-_73256838 0.13 ENST00000297873.4
WBSCR27
Williams Beuren syndrome chromosome region 27
chr15_-_81202118 0.12 ENST00000560560.1
RP11-351M8.1
Uncharacterized protein
chr15_+_73976715 0.12 ENST00000558689.1
ENST00000560786.2
ENST00000561213.1
ENST00000563584.1
ENST00000561416.1
CD276
CD276 molecule
chr21_+_45209394 0.12 ENST00000497547.1
RRP1
ribosomal RNA processing 1
chr3_+_50192457 0.12 ENST00000414301.1
ENST00000450338.1
SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr3_+_14444063 0.12 ENST00000454876.2
ENST00000360861.3
ENST00000416216.2
SLC6A6
solute carrier family 6 (neurotransmitter transporter), member 6
chr1_-_111991908 0.12 ENST00000235090.5
WDR77
WD repeat domain 77
chr19_-_6433765 0.12 ENST00000321510.6
SLC25A41
solute carrier family 25, member 41
chr12_-_106477805 0.12 ENST00000553094.1
ENST00000549704.1
NUAK1
NUAK family, SNF1-like kinase, 1
chr2_-_46769694 0.12 ENST00000522587.1
ATP6V1E2
ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2
chrX_+_18725758 0.12 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
PPEF1
protein phosphatase, EF-hand calcium binding domain 1
chr17_+_60704762 0.12 ENST00000303375.5
MRC2
mannose receptor, C type 2
chr1_+_65775204 0.11 ENST00000371069.4
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr1_-_89641680 0.11 ENST00000294671.2
GBP7
guanylate binding protein 7
chr19_-_46142680 0.11 ENST00000245925.3
EML2
echinoderm microtubule associated protein like 2
chr6_+_90272339 0.11 ENST00000522779.1
ANKRD6
ankyrin repeat domain 6
chr17_-_67057203 0.10 ENST00000340001.4
ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr7_+_2671663 0.10 ENST00000407643.1
TTYH3
tweety family member 3
chr17_-_67057114 0.10 ENST00000370732.2
ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr22_-_42739533 0.10 ENST00000515426.1
TCF20
transcription factor 20 (AR1)
chr9_-_117420052 0.10 ENST00000423632.1
RP11-402G3.5
RP11-402G3.5
chr13_-_29069232 0.10 ENST00000282397.4
ENST00000541932.1
ENST00000539099.1
FLT1
fms-related tyrosine kinase 1
chr17_-_40428359 0.10 ENST00000293328.3
STAT5B
signal transducer and activator of transcription 5B
chr3_-_45838011 0.10 ENST00000358525.4
ENST00000413781.1
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr3_+_141105705 0.10 ENST00000513258.1
ZBTB38
zinc finger and BTB domain containing 38
chr13_+_42712178 0.09 ENST00000536612.1
DGKH
diacylglycerol kinase, eta
chr17_+_37894570 0.09 ENST00000394211.3
GRB7
growth factor receptor-bound protein 7
chr4_-_40632881 0.09 ENST00000511598.1
RBM47
RNA binding motif protein 47
chr14_+_55033815 0.09 ENST00000554335.1
SAMD4A
sterile alpha motif domain containing 4A
chr9_-_35103105 0.09 ENST00000452248.2
ENST00000356493.5
STOML2
stomatin (EPB72)-like 2
chrX_-_129299847 0.09 ENST00000319908.3
ENST00000287295.3
AIFM1
apoptosis-inducing factor, mitochondrion-associated, 1
chr4_-_7941596 0.09 ENST00000420658.1
ENST00000358461.2
AFAP1
actin filament associated protein 1
chr19_+_38880695 0.08 ENST00000587947.1
ENST00000338502.4
SPRED3
sprouty-related, EVH1 domain containing 3
chrX_+_91034260 0.08 ENST00000395337.2
PCDH11X
protocadherin 11 X-linked
chr19_-_16582815 0.08 ENST00000455140.2
ENST00000248070.6
ENST00000594975.1
EPS15L1
epidermal growth factor receptor pathway substrate 15-like 1
chr7_-_35734607 0.08 ENST00000427455.1
HERPUD2
HERPUD family member 2
chr19_+_41509851 0.08 ENST00000593831.1
ENST00000330446.5
CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr11_+_120207787 0.08 ENST00000397843.2
ENST00000356641.3
ARHGEF12
Rho guanine nucleotide exchange factor (GEF) 12
chr2_+_54951679 0.08 ENST00000356458.6
EML6
echinoderm microtubule associated protein like 6
chr4_-_40632844 0.08 ENST00000505414.1
RBM47
RNA binding motif protein 47
chr3_+_32859510 0.08 ENST00000383763.5
TRIM71
tripartite motif containing 71, E3 ubiquitin protein ligase
chr3_-_45837959 0.08 ENST00000353278.4
ENST00000456124.2
SLC6A20
solute carrier family 6 (proline IMINO transporter), member 20
chr1_-_113249948 0.08 ENST00000339083.7
ENST00000369642.3
RHOC
ras homolog family member C
chr11_+_63606477 0.08 ENST00000508192.1
ENST00000361128.5
MARK2
MAP/microtubule affinity-regulating kinase 2
chrX_+_46771711 0.07 ENST00000424392.1
ENST00000397189.1
PHF16
jade family PHD finger 3
chr16_-_755819 0.07 ENST00000397621.1
FBXL16
F-box and leucine-rich repeat protein 16
chr19_-_58609570 0.07 ENST00000600845.1
ENST00000240727.6
ENST00000600897.1
ENST00000421612.2
ENST00000601063.1
ENST00000601144.1
ZSCAN18
zinc finger and SCAN domain containing 18
chr7_-_107968999 0.07 ENST00000456431.1
NRCAM
neuronal cell adhesion molecule
chrX_+_153770421 0.07 ENST00000369609.5
ENST00000369607.1
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr5_-_64920115 0.07 ENST00000381018.3
ENST00000274327.7
TRIM23
tripartite motif containing 23
chr16_-_67427389 0.07 ENST00000562206.1
ENST00000290942.5
ENST00000393957.2
TPPP3
tubulin polymerization-promoting protein family member 3
chr1_+_161087873 0.07 ENST00000368009.2
ENST00000368007.4
ENST00000368008.1
ENST00000392190.5
NIT1
nitrilase 1
chrX_+_118425471 0.07 ENST00000428222.1
RP5-1139I1.1
RP5-1139I1.1
chr2_+_232457569 0.07 ENST00000313965.2
C2orf57
chromosome 2 open reading frame 57
chr11_+_7598239 0.06 ENST00000525597.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr10_-_33623564 0.06 ENST00000374875.1
ENST00000374822.4
NRP1
neuropilin 1
chr4_-_40632757 0.06 ENST00000511902.1
ENST00000505220.1
RBM47
RNA binding motif protein 47
chr1_-_113249678 0.06 ENST00000369633.2
ENST00000425265.2
ENST00000369632.2
ENST00000436685.2
RHOC
ras homolog family member C
chr2_-_99552620 0.06 ENST00000428096.1
ENST00000397899.2
ENST00000420294.1
KIAA1211L
KIAA1211-like
chr1_-_161087802 0.06 ENST00000368010.3
PFDN2
prefoldin subunit 2
chr7_+_39017504 0.06 ENST00000403058.1
POU6F2
POU class 6 homeobox 2
chr16_-_11485922 0.06 ENST00000599216.1
CTD-3088G3.8
Protein LOC388210
chr1_-_43833628 0.06 ENST00000413844.2
ENST00000372458.3
ELOVL1
ELOVL fatty acid elongase 1
chr22_+_21369316 0.06 ENST00000413302.2
ENST00000402329.3
ENST00000336296.2
ENST00000401443.1
ENST00000443995.3
P2RX6
purinergic receptor P2X, ligand-gated ion channel, 6
chr19_-_50168962 0.06 ENST00000599223.1
ENST00000593922.1
ENST00000600022.1
ENST00000596765.1
ENST00000599144.1
ENST00000596822.1
ENST00000598108.1
ENST00000601373.1
ENST00000595034.1
ENST00000601291.1
IRF3
interferon regulatory factor 3
chr18_-_52989217 0.06 ENST00000570287.2
TCF4
transcription factor 4
chr15_+_73976545 0.06 ENST00000318443.5
ENST00000537340.2
ENST00000318424.5
CD276
CD276 molecule
chr17_-_53809473 0.06 ENST00000575734.1
TMEM100
transmembrane protein 100
chr19_-_50169064 0.06 ENST00000593337.1
ENST00000598808.1
ENST00000600453.1
ENST00000593818.1
ENST00000597198.1
ENST00000601809.1
ENST00000377139.3
IRF3
interferon regulatory factor 3
chr15_-_43863695 0.06 ENST00000439195.1
PPIP5K1
diphosphoinositol pentakisphosphate kinase 1
chr22_-_30953587 0.05 ENST00000453479.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr19_+_35940486 0.05 ENST00000246549.2
FFAR2
free fatty acid receptor 2
chr6_+_28109703 0.04 ENST00000457389.2
ENST00000330236.6
ZKSCAN8
zinc finger with KRAB and SCAN domains 8
chr1_-_113249734 0.04 ENST00000484054.3
ENST00000369636.2
ENST00000369637.1
ENST00000285735.2
ENST00000369638.2
RHOC
ras homolog family member C
chr4_-_40632140 0.04 ENST00000514782.1
RBM47
RNA binding motif protein 47
chr17_-_6947225 0.04 ENST00000574600.1
ENST00000308009.1
ENST00000447225.1
SLC16A11
solute carrier family 16, member 11
chrX_+_68835911 0.04 ENST00000525810.1
ENST00000527388.1
ENST00000374553.2
ENST00000374552.4
ENST00000338901.3
ENST00000524573.1
EDA
ectodysplasin A
chr17_-_5372271 0.04 ENST00000225296.3
DHX33
DEAH (Asp-Glu-Ala-His) box polypeptide 33
chr4_-_175750364 0.04 ENST00000340217.5
ENST00000274093.3
GLRA3
glycine receptor, alpha 3

Network of associatons between targets according to the STRING database.

First level regulatory network of ZIC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.6 GO:0060024 rhythmic synaptic transmission(GO:0060024) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.1 0.3 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.1 0.2 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.1 0.4 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1 0.3 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.1 0.4 GO:0000255 allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449)
0.1 0.5 GO:1903826 arginine transmembrane transport(GO:1903826)
0.1 0.3 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.3 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 0.2 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.1 0.2 GO:0099558 maintenance of synapse structure(GO:0099558)
0.1 0.3 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1 0.2 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0 0.2 GO:0043553 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.2 GO:0060266 positive regulation of respiratory burst involved in inflammatory response(GO:0060265) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.4 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.0 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.3 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.3 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.0 0.1 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.0 0.4 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
0.0 0.6 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.9 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.2 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.0 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232)
0.0 0.2 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.1 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.0 0.4 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.4 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.3 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.7 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.4 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 0.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.2 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.4 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.3 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.2 GO:0015824 proline transport(GO:0015824)
0.0 0.2 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.1 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.0 0.1 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 0.1 GO:0051493 regulation of cytoskeleton organization(GO:0051493)
0.0 0.4 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.1 GO:0016191 synaptic vesicle uncoating(GO:0016191)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0044301 climbing fiber(GO:0044301)
0.0 0.2 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.7 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.7 GO:0031105 septin complex(GO:0031105)
0.0 0.3 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.3 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.3 GO:0034709 methylosome(GO:0034709)
0.0 0.0 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.0 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.1 0.4 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.1 0.4 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.3 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.2 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.1 0.5 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.4 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.4 GO:0000182 rDNA binding(GO:0000182)
0.0 0.7 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.4 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.2 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.6 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0016274 arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.0 0.1 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.3 GO:0008430 selenium binding(GO:0008430)
0.0 0.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0 0.3 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.4 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.7 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.6 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.4 PID IL5 PATHWAY IL5-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.5 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.7 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.7 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling