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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for UGUGCUU
Z-value: 0.99
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miRNA associated with seed UGUGCUU
| Name | miRBASE accession |
|---|---|
|
hsa-miR-218-5p
|
MIMAT0000275 |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr3_-_182698381 Show fit | 0.77 |
ENST00000292782.4
|
DCN1, defective in cullin neddylation 1, domain containing 1 |
|
| chr8_+_125486939 Show fit | 0.70 |
ENST00000303545.3
|
ring finger protein 139 |
|
| chr3_+_88188254 Show fit | 0.63 |
ENST00000309495.5
|
zinc finger protein 654 |
|
| chr10_+_22610124 Show fit | 0.60 |
ENST00000376663.3
|
BMI1 polycomb ring finger oncogene |
|
| chr8_-_25315905 Show fit | 0.60 |
ENST00000221200.4
|
potassium channel tetramerization domain containing 9 |
|
| chrX_-_134049262 Show fit | 0.55 |
ENST00000370783.3
|
motile sperm domain containing 1 |
|
| chr1_-_197169672 Show fit | 0.54 |
ENST00000367405.4
|
zinc finger and BTB domain containing 41 |
|
| chr21_+_35445827 Show fit | 0.52 |
ENST00000608209.1
ENST00000381151.3 |
sodium/myo-inositol cotransporter solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
|
| chr2_+_46769798 Show fit | 0.52 |
ENST00000238738.4
|
ras homolog family member Q |
|
| chr8_+_48920960 Show fit | 0.49 |
ENST00000523111.2
ENST00000523432.1 ENST00000521346.1 ENST00000517630.1 |
ubiquitin-conjugating enzyme E2 variant 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of UGUGCUU
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.0 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.0 | 0.8 | GO:0007379 | segment specification(GO:0007379) |
| 0.0 | 0.7 | GO:0060628 | regulation of ER to Golgi vesicle-mediated transport(GO:0060628) |
| 0.0 | 0.6 | GO:0090005 | negative regulation of establishment of protein localization to plasma membrane(GO:0090005) |
| 0.0 | 0.6 | GO:0050650 | chondroitin sulfate proteoglycan biosynthetic process(GO:0050650) |
| 0.1 | 0.5 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
| 0.1 | 0.5 | GO:0015798 | myo-inositol transport(GO:0015798) |
| 0.0 | 0.5 | GO:0045722 | positive regulation of gluconeogenesis(GO:0045722) |
| 0.0 | 0.5 | GO:0000729 | DNA double-strand break processing(GO:0000729) |
| 0.0 | 0.4 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.0 | 0.7 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
| 0.2 | 0.5 | GO:0031372 | UBC13-MMS2 complex(GO:0031372) |
| 0.0 | 0.5 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
| 0.1 | 0.4 | GO:0000801 | central element(GO:0000801) |
| 0.0 | 0.4 | GO:0070083 | clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083) |
| 0.0 | 0.4 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.0 | 0.4 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.0 | 0.3 | GO:0033565 | ESCRT-0 complex(GO:0033565) |
| 0.0 | 0.3 | GO:0031415 | NatA complex(GO:0031415) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.6 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.0 | 0.8 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.1 | 0.6 | GO:0071535 | RING-like zinc finger domain binding(GO:0071535) |
| 0.0 | 0.6 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.0 | 0.6 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650) |
| 0.2 | 0.5 | GO:0005365 | myo-inositol transmembrane transporter activity(GO:0005365) |
| 0.1 | 0.5 | GO:0032427 | GBD domain binding(GO:0032427) |
| 0.1 | 0.5 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
| 0.0 | 0.5 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.0 | 0.4 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.9 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.0 | 0.3 | PID IL5 PATHWAY | IL5-mediated signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.0 | 0.4 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.0 | 0.3 | REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
| 0.0 | 0.3 | REACTOME REGULATED PROTEOLYSIS OF P75NTR | Genes involved in Regulated proteolysis of p75NTR |
| 0.0 | 0.3 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.0 | 0.3 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.0 | 0.3 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.0 | 0.3 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.0 | 0.2 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 0.0 | 0.2 | REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |