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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for UBP1

Z-value: 0.37

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Transcription factors associated with UBP1

Gene Symbol Gene ID Gene Info
ENSG00000153560.7 upstream binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
UBP1hg19_v2_chr3_-_33481835_334819050.276.1e-01Click!

Activity profile of UBP1 motif

Sorted Z-values of UBP1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_228678550 0.19 ENST00000409189.3
ENST00000358813.4
chemokine (C-C motif) ligand 20
chr5_+_122847908 0.15 ENST00000511130.2
ENST00000512718.3
casein kinase 1, gamma 3
chr2_-_163175133 0.14 ENST00000421365.2
ENST00000263642.2
interferon induced with helicase C domain 1
chr5_+_122847781 0.13 ENST00000395412.1
ENST00000395411.1
ENST00000345990.4
casein kinase 1, gamma 3
chr5_-_111093759 0.13 ENST00000509979.1
ENST00000513100.1
ENST00000508161.1
ENST00000455559.2
neuronal regeneration related protein
chr9_-_14322319 0.12 ENST00000606230.1
nuclear factor I/B
chr22_+_22676808 0.12 ENST00000390290.2
immunoglobulin lambda variable 1-51
chr11_-_60623437 0.11 ENST00000332539.4
prostaglandin D2 receptor 2
chr4_-_100815525 0.11 ENST00000226522.8
ENST00000499666.2
late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
chrX_+_24167828 0.11 ENST00000379188.3
ENST00000419690.1
ENST00000379177.1
ENST00000304543.5
zinc finger protein, X-linked
chr2_+_170550944 0.10 ENST00000359744.3
ENST00000438838.1
ENST00000438710.1
ENST00000449906.1
ENST00000498202.2
ENST00000272797.4
phosphatase, orphan 2
kelch-like family member 23
chr2_+_162087577 0.09 ENST00000439442.1
TRAF family member-associated NFKB activator
chr12_-_123717711 0.09 ENST00000537854.1
M-phase phosphoprotein 9
chrX_+_24167746 0.08 ENST00000428571.1
ENST00000539115.1
zinc finger protein, X-linked
chr19_+_917287 0.08 ENST00000592648.1
ENST00000234371.5
KISS1 receptor
chr11_-_134123142 0.08 ENST00000392595.2
ENST00000341541.3
ENST00000352327.5
ENST00000392594.3
thymocyte nuclear protein 1
chr1_-_150208498 0.08 ENST00000314136.8
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr1_-_150208363 0.08 ENST00000436748.2
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr1_-_150208412 0.08 ENST00000532744.1
ENST00000369114.5
ENST00000369115.2
ENST00000369116.4
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr17_-_27188984 0.07 ENST00000582320.2
microRNA 451b
chr7_+_142829162 0.07 ENST00000291009.3
prolactin-induced protein
chr1_-_185126037 0.07 ENST00000367506.5
ENST00000367504.3
tRNA methyltransferase 1 homolog (S. cerevisiae)-like
chr7_+_105172612 0.06 ENST00000493041.1
RAD50 interactor 1
chrX_+_115567767 0.06 ENST00000371900.4
solute carrier family 6 (amino acid transporter), member 14
chr11_-_14521379 0.06 ENST00000249923.3
ENST00000529866.1
ENST00000439561.2
ENST00000534771.1
coatomer protein complex, subunit beta 1
chr1_+_63989004 0.06 ENST00000371088.4
EF-hand calcium binding domain 7
chr9_-_6015607 0.06 ENST00000259569.5
RAN binding protein 6
chr5_+_95998070 0.05 ENST00000421689.2
ENST00000510756.1
ENST00000512620.1
calpastatin
chr12_+_101188547 0.05 ENST00000546991.1
ENST00000392979.3
anoctamin 4
chrX_+_74493896 0.05 ENST00000373383.4
ENST00000373379.1
uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
chr1_-_150208320 0.05 ENST00000534220.1
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr1_-_150669604 0.05 ENST00000427665.1
ENST00000540514.1
golgi phosphoprotein 3-like
chr6_+_31555045 0.05 ENST00000396101.3
ENST00000490742.1
leukocyte specific transcript 1
chr14_-_92413727 0.05 ENST00000267620.10
fibulin 5
chr14_+_75988768 0.05 ENST00000286639.6
basic leucine zipper transcription factor, ATF-like
chr10_-_27443294 0.05 ENST00000396296.3
ENST00000375972.3
ENST00000376016.3
ENST00000491542.2
YME1-like 1 ATPase
chr10_-_27443155 0.05 ENST00000427324.1
ENST00000326799.3
YME1-like 1 ATPase
chr1_-_202129704 0.04 ENST00000476061.1
ENST00000544762.1
ENST00000467283.1
ENST00000464870.1
ENST00000435759.2
ENST00000486116.1
ENST00000543735.1
ENST00000308986.5
ENST00000477625.1
protein tyrosine phosphatase, non-receptor type 7
chr11_-_113345995 0.04 ENST00000355319.2
ENST00000542616.1
dopamine receptor D2
chr2_+_61244697 0.04 ENST00000401576.1
ENST00000295030.5
ENST00000414712.2
peroxisomal biogenesis factor 13
chr13_-_23949671 0.04 ENST00000402364.1
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr5_-_93447333 0.04 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
family with sequence similarity 172, member A
chr12_+_123717458 0.04 ENST00000253233.1
chromosome 12 open reading frame 65
chr6_+_142623758 0.04 ENST00000541199.1
ENST00000435011.2
G protein-coupled receptor 126
chrX_-_10851762 0.04 ENST00000380785.1
ENST00000380787.1
midline 1 (Opitz/BBB syndrome)
chr12_+_123717967 0.04 ENST00000536130.1
ENST00000546132.1
chromosome 12 open reading frame 65
chr14_-_92413353 0.04 ENST00000556154.1
fibulin 5
chr12_-_47473425 0.03 ENST00000550413.1
adhesion molecule with Ig-like domain 2
chr15_-_101835110 0.03 ENST00000560496.1
small nuclear ribonucleoprotein polypeptide A'
chr11_-_11374904 0.03 ENST00000528848.2
casein kinase 2, alpha 3 polypeptide
chr5_-_41510656 0.03 ENST00000377801.3
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr12_-_123717643 0.03 ENST00000541437.1
ENST00000606320.1
M-phase phosphoprotein 9
chr11_-_102668879 0.03 ENST00000315274.6
matrix metallopeptidase 1 (interstitial collagenase)
chr3_+_111260980 0.03 ENST00000438817.2
CD96 molecule
chr9_+_109685630 0.03 ENST00000451160.2
Uncharacterized protein
chr1_-_150208291 0.03 ENST00000533654.1
acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr1_-_202129105 0.03 ENST00000367279.4
protein tyrosine phosphatase, non-receptor type 7
chr15_+_41136734 0.02 ENST00000568580.1
serine peptidase inhibitor, Kunitz type 1
chr2_+_17721920 0.02 ENST00000295156.4
visinin-like 1
chr21_+_43823983 0.02 ENST00000291535.6
ENST00000450356.1
ENST00000319294.6
ENST00000398367.1
ubiquitin associated and SH3 domain containing A
chr3_-_56502375 0.02 ENST00000288221.6
ELKS/RAB6-interacting/CAST family member 2
chr5_+_34656331 0.02 ENST00000265109.3
retinoic acid induced 14
chrX_+_149887090 0.02 ENST00000538506.1
myotubularin related protein 1
chr19_-_59066327 0.02 ENST00000596708.1
ENST00000601220.1
ENST00000597848.1
charged multivesicular body protein 2A
chr15_+_34638066 0.02 ENST00000333756.4
NUT midline carcinoma, family member 1
chr2_+_113033164 0.02 ENST00000409871.1
ENST00000343936.4
zinc finger CCCH-type containing 6
chr6_-_47009996 0.02 ENST00000371243.2
G protein-coupled receptor 110
chr7_+_132937820 0.02 ENST00000393161.2
ENST00000253861.4
exocyst complex component 4
chr14_-_75330537 0.02 ENST00000556084.2
ENST00000556489.2
ENST00000445876.1
prospero homeobox 2
chr4_-_168155700 0.02 ENST00000357545.4
ENST00000512648.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr19_-_49864746 0.02 ENST00000598810.1
TEA domain family member 2
chr14_-_77542485 0.02 ENST00000556781.1
ENST00000557526.1
ENST00000555512.1
RP11-7F17.3
chr5_-_131329918 0.02 ENST00000357096.1
ENST00000431707.1
ENST00000434099.1
acyl-CoA synthetase long-chain family member 6
chr9_+_15422702 0.01 ENST00000380821.3
ENST00000421710.1
small nuclear RNA activating complex, polypeptide 3, 50kDa
chr1_-_114302086 0.01 ENST00000369604.1
ENST00000357783.2
putative homeodomain transcription factor 1
chr5_-_111093717 0.01 ENST00000507032.2
neuronal regeneration related protein
chr6_-_29395509 0.01 ENST00000377147.2
olfactory receptor, family 11, subfamily A, member 1
chr2_+_166430619 0.01 ENST00000409420.1
cysteine-serine-rich nuclear protein 3
chr4_-_76861392 0.01 ENST00000505594.1
N-acylethanolamine acid amidase
chr11_+_7506713 0.01 ENST00000329293.3
ENST00000534244.1
olfactomedin-like 1
chr14_-_23395623 0.01 ENST00000556043.1
protein arginine methyltransferase 5
chr10_-_75676400 0.01 ENST00000412307.2
chromosome 10 open reading frame 55
chr9_-_130889990 0.01 ENST00000449878.1
prostaglandin E synthase 2
chr4_-_57524061 0.01 ENST00000508121.1
HOP homeobox
chr13_+_24844979 0.01 ENST00000454083.1
spermatogenesis associated 13
chr15_-_42343388 0.01 ENST00000399518.3
phospholipase A2, group IVE
chr4_+_55096489 0.00 ENST00000504461.1
platelet-derived growth factor receptor, alpha polypeptide
chr1_-_153599732 0.00 ENST00000392623.1
S100 calcium binding protein A13
chrX_+_38420623 0.00 ENST00000378482.2
tetraspanin 7
chr8_-_107782463 0.00 ENST00000311955.3
actin-binding Rho activating protein
chr8_-_28747424 0.00 ENST00000523436.1
ENST00000397363.4
ENST00000521777.1
ENST00000520184.1
ENST00000521022.1
integrator complex subunit 9
chr22_+_38071615 0.00 ENST00000215909.5
lectin, galactoside-binding, soluble, 1
chr1_+_155108294 0.00 ENST00000303343.8
ENST00000368404.4
ENST00000368401.5
solute carrier family 50 (sugar efflux transporter), member 1
chr9_+_112852477 0.00 ENST00000480388.1
A kinase (PRKA) anchor protein 2
chr3_+_29323043 0.00 ENST00000452462.1
ENST00000456853.1
RNA binding motif, single stranded interacting protein 3
chr19_-_58459039 0.00 ENST00000282308.3
ENST00000598928.1
zinc finger protein 256
chr8_-_28747717 0.00 ENST00000416984.2
integrator complex subunit 9
chr1_-_144995002 0.00 ENST00000369356.4
phosphodiesterase 4D interacting protein

Network of associatons between targets according to the STRING database.

First level regulatory network of UBP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0042222 interleukin-1 biosynthetic process(GO:0042222) regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.0 0.1 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:0072425 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.0 0.0 GO:0060152 peroxisome localization(GO:0060151) microtubule-based peroxisome localization(GO:0060152)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.3 GO:0000812 Swr1 complex(GO:0000812)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)