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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for TFDP1
Z-value: 1.07
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Transcription factors associated with TFDP1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| TFDP1 | hg19_v2_chr13_+_114238997_114239077 | -0.73 | 9.8e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr17_-_73179046 Show fit | 0.99 |
ENST00000314523.7
ENST00000420826.2 |
small ubiquitin-like modifier 2 |
|
| chr11_+_85956182 Show fit | 0.94 |
ENST00000327320.4
ENST00000351625.6 ENST00000534595.1 |
embryonic ectoderm development |
|
| chr3_-_113464906 Show fit | 0.89 |
ENST00000477813.1
|
N(alpha)-acetyltransferase 50, NatE catalytic subunit |
|
| chr9_+_96717821 Show fit | 0.78 |
ENST00000454594.1
|
RP11-231K24.2 |
|
| chr10_-_77161004 Show fit | 0.69 |
ENST00000418818.2
|
RP11-399K21.11 |
|
| chr15_+_44719394 Show fit | 0.68 |
ENST00000260327.4
ENST00000396780.1 |
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 |
|
| chr17_+_41177220 Show fit | 0.67 |
ENST00000587250.2
ENST00000544533.1 |
Rho family GTPase 2 |
|
| chr16_+_53164956 Show fit | 0.66 |
ENST00000563410.1
|
chromodomain helicase DNA binding protein 9 |
|
| chr1_+_27113963 Show fit | 0.64 |
ENST00000430292.1
|
phosphatidylinositol glycan anchor biosynthesis, class V |
|
| chr10_-_98347063 Show fit | 0.63 |
ENST00000443638.1
|
transmembrane 9 superfamily member 3 |
Network of associatons between targets according to the STRING database.
First level regulatory network of TFDP1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.1 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
| 0.0 | 1.9 | GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886) |
| 0.0 | 1.6 | GO:0030317 | sperm motility(GO:0030317) |
| 0.3 | 1.4 | GO:2000176 | regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176) |
| 0.0 | 1.4 | GO:0050885 | neuromuscular process controlling balance(GO:0050885) |
| 0.1 | 1.2 | GO:0051256 | mitotic spindle midzone assembly(GO:0051256) |
| 0.3 | 1.1 | GO:0015910 | peroxisomal long-chain fatty acid import(GO:0015910) |
| 0.1 | 1.1 | GO:0070601 | centromeric sister chromatid cohesion(GO:0070601) |
| 0.0 | 1.1 | GO:0035666 | TRIF-dependent toll-like receptor signaling pathway(GO:0035666) |
| 0.1 | 1.0 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.4 | GO:0031415 | NatA complex(GO:0031415) |
| 0.2 | 1.3 | GO:0097452 | GAIT complex(GO:0097452) |
| 0.1 | 1.2 | GO:0060091 | kinocilium(GO:0060091) |
| 0.0 | 1.2 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.0 | 1.2 | GO:0005811 | lipid particle(GO:0005811) |
| 0.1 | 1.1 | GO:0001739 | sex chromatin(GO:0001739) |
| 0.0 | 1.1 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 1.0 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.1 | 0.9 | GO:0097422 | tubular endosome(GO:0097422) |
| 0.1 | 0.9 | GO:0005955 | calcineurin complex(GO:0005955) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.7 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
| 0.1 | 1.4 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.1 | 1.4 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.1 | 1.3 | GO:0031386 | protein tag(GO:0031386) |
| 0.0 | 1.3 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.2 | 1.1 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.0 | 1.1 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.0 | 1.0 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
| 0.1 | 0.9 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 0.1 | 0.9 | GO:0097100 | supercoiled DNA binding(GO:0097100) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.0 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 1.8 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 0.0 | 1.2 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.0 | 1.1 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 1.1 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.0 | 1.0 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.0 | 0.7 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 0.6 | PID MYC PATHWAY | C-MYC pathway |
| 0.0 | 0.6 | ST PHOSPHOINOSITIDE 3 KINASE PATHWAY | PI3K Pathway |
| 0.0 | 0.5 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.7 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.0 | 1.4 | REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE | Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase |
| 0.0 | 1.3 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.0 | 1.3 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 1.3 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 1.2 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.0 | 1.1 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.0 | 1.0 | REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS | Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins |
| 0.1 | 0.9 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 0.0 | 0.9 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |