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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TFAP4_MSC

Z-value: 1.12

Motif logo

Transcription factors associated with TFAP4_MSC

Gene Symbol Gene ID Gene Info
ENSG00000090447.7 transcription factor AP-4
ENSG00000178860.8 musculin

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TFAP4hg19_v2_chr16_-_4323015_4323076-0.305.6e-01Click!
MSChg19_v2_chr8_-_72756667_727567360.305.7e-01Click!

Activity profile of TFAP4_MSC motif

Sorted Z-values of TFAP4_MSC motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_68845417 1.39 ENST00000542875.1
RP11-81H14.2
chr2_+_33701684 1.00 ENST00000442390.1
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr2_-_42160486 0.94 ENST00000427054.1
AC104654.2
chr15_-_40401062 0.69 ENST00000354670.4
ENST00000559701.1
ENST00000557870.1
ENST00000558774.1
Bcl2 modifying factor
chr16_-_21289627 0.68 ENST00000396023.2
ENST00000415987.2
crystallin, mu
chr8_-_123706338 0.55 ENST00000521608.1
long intergenic non-protein coding RNA 1151
chr14_-_91282821 0.47 ENST00000553948.1
tetratricopeptide repeat domain 7B
chr2_+_233404429 0.47 ENST00000389494.3
ENST00000389492.3
cholinergic receptor, nicotinic, gamma (muscle)
chr3_-_178790057 0.46 ENST00000311417.2
zinc finger, matrin-type 3
chr3_-_178789220 0.45 ENST00000414084.1
zinc finger, matrin-type 3
chr14_+_104710541 0.45 ENST00000419115.1
chromosome 14 open reading frame 144
chr10_+_1102303 0.43 ENST00000381329.1
WD repeat domain 37
chr8_-_95961578 0.42 ENST00000448464.2
ENST00000342697.4
tumor protein p53 inducible nuclear protein 1
chr5_+_148960931 0.41 ENST00000333677.6
Rho guanine nucleotide exchange factor (GEF) 37
chr2_+_33701707 0.40 ENST00000425210.1
ENST00000444784.1
ENST00000423159.1
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr15_+_75487984 0.37 ENST00000563905.1
chromosome 15 open reading frame 39
chrX_-_30326445 0.36 ENST00000378963.1
nuclear receptor subfamily 0, group B, member 1
chr20_+_33292507 0.33 ENST00000414082.1
tumor protein p53 inducible nuclear protein 2
chr12_+_57828521 0.32 ENST00000309668.2
inhibin, beta C
chr20_+_34679725 0.32 ENST00000432589.1
erythrocyte membrane protein band 4.1-like 1
chr10_+_80027105 0.32 ENST00000461034.1
ENST00000476909.1
ENST00000459633.1
long intergenic non-protein coding RNA 595
chr3_-_52869205 0.31 ENST00000446157.2
musculoskeletal, embryonic nuclear protein 1
chr12_+_69201923 0.31 ENST00000462284.1
ENST00000258149.5
ENST00000356290.4
ENST00000540827.1
ENST00000428863.2
ENST00000393412.3
MDM2 oncogene, E3 ubiquitin protein ligase
chr16_-_31105870 0.31 ENST00000394971.3
vitamin K epoxide reductase complex, subunit 1
chr4_-_153303658 0.30 ENST00000296555.5
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr9_+_102584128 0.29 ENST00000338488.4
ENST00000395097.2
nuclear receptor subfamily 4, group A, member 3
chr4_+_37892682 0.29 ENST00000508802.1
ENST00000261439.4
ENST00000402522.1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr8_+_87111059 0.28 ENST00000285393.3
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr3_+_69134124 0.28 ENST00000478935.1
ADP-ribosylation-like factor 6 interacting protein 5
chr1_+_153600869 0.27 ENST00000292169.1
ENST00000368696.3
ENST00000436839.1
S100 calcium binding protein A1
chr8_-_145016692 0.27 ENST00000357649.2
plectin
chr17_+_7461849 0.27 ENST00000338784.4
tumor necrosis factor (ligand) superfamily, member 13
chr17_-_27467418 0.26 ENST00000528564.1
myosin XVIIIA
chr1_+_203256898 0.25 ENST00000433008.1
RP11-134P9.3
chr5_-_173173171 0.25 ENST00000517733.1
ENST00000518902.1
CTB-43E15.3
chr12_-_86650077 0.25 ENST00000552808.2
ENST00000547225.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr1_+_212738676 0.25 ENST00000366981.4
ENST00000366987.2
activating transcription factor 3
chr2_+_95537248 0.24 ENST00000427593.2
tektin 4
chr11_+_33061336 0.24 ENST00000602733.1
t-complex 11, testis-specific-like 1
chr17_+_45286387 0.24 ENST00000572316.1
ENST00000354968.1
ENST00000576874.1
ENST00000536623.2
myosin, light chain 4, alkali; atrial, embryonic
chr1_-_206945830 0.24 ENST00000423557.1
interleukin 10
chr8_+_9413410 0.23 ENST00000520408.1
ENST00000310430.6
ENST00000522110.1
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr2_-_73460334 0.23 ENST00000258083.2
protease-associated domain containing 1
chr16_+_2570340 0.23 ENST00000568263.1
ENST00000293971.6
ENST00000302956.4
ENST00000413459.3
ENST00000566706.1
ENST00000569879.1
amidohydrolase domain containing 2
chr20_-_39317868 0.22 ENST00000373313.2
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
chr3_-_52486841 0.22 ENST00000496590.1
troponin C type 1 (slow)
chr15_-_67439270 0.22 ENST00000558463.1
Uncharacterized protein
chr1_+_178482262 0.22 ENST00000367641.3
ENST00000367639.1
testis expressed 35
chr21_+_17791648 0.22 ENST00000602892.1
ENST00000418813.2
ENST00000435697.1
long intergenic non-protein coding RNA 478
chr2_+_11752379 0.22 ENST00000396123.1
growth regulation by estrogen in breast cancer 1
chr17_+_65040678 0.21 ENST00000226021.3
calcium channel, voltage-dependent, gamma subunit 1
chr17_+_76037081 0.21 ENST00000588549.1
trinucleotide repeat containing 6C
chr15_-_52944231 0.21 ENST00000546305.2
family with sequence similarity 214, member A
chr19_+_36249044 0.20 ENST00000444637.2
ENST00000396908.4
ENST00000544099.1
chromosome 19 open reading frame 55
chr20_-_31124186 0.20 ENST00000375678.3
chromosome 20 open reading frame 112
chr19_-_56663250 0.20 ENST00000376271.1
Uncharacterized protein
chr12_-_133464118 0.19 ENST00000540963.1
checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
chr2_+_177001685 0.19 ENST00000432796.2
homeobox D3
chr22_-_37882395 0.19 ENST00000416983.3
ENST00000424765.2
ENST00000356998.3
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr8_-_42396185 0.18 ENST00000518717.1
solute carrier family 20 (phosphate transporter), member 2
chr4_-_164534657 0.18 ENST00000339875.5
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr8_-_144679264 0.18 ENST00000531953.1
ENST00000526133.1
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr2_+_37311588 0.18 ENST00000409774.1
ENST00000608836.1
G patch domain containing 11
chr6_-_133055815 0.18 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
vanin 3
chr1_-_161168834 0.18 ENST00000367995.3
ENST00000367996.5
ADAM metallopeptidase with thrombospondin type 1 motif, 4
chr2_-_179914760 0.18 ENST00000420890.2
ENST00000409284.1
ENST00000443758.1
ENST00000446116.1
coiled-coil domain containing 141
chr4_+_39408470 0.18 ENST00000257408.4
klotho beta
chr2_+_27505260 0.18 ENST00000380075.2
ENST00000296098.4
tripartite motif containing 54
chr7_+_134832808 0.18 ENST00000275767.3
transmembrane protein 140
chrY_+_14774265 0.18 ENST00000457658.1
ENST00000440408.1
ENST00000543097.1
testis-specific transcript, Y-linked 15 (non-protein coding)
chr1_-_9129735 0.17 ENST00000377424.4
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chrX_+_15756382 0.17 ENST00000318636.3
carbonic anhydrase VB, mitochondrial
chr12_-_70093111 0.17 ENST00000548658.1
ENST00000476098.1
ENST00000331471.4
ENST00000393365.1
bestrophin 3
chr12_-_54121212 0.17 ENST00000548263.1
ENST00000430117.2
ENST00000550804.1
ENST00000549173.1
ENST00000551900.1
ENST00000546619.1
ENST00000548177.1
ENST00000549349.1
calcium binding and coiled-coil domain 1
chr17_+_34901353 0.17 ENST00000593016.1
gametogenetin binding protein 2
chr15_+_49715293 0.17 ENST00000267843.4
ENST00000560270.1
fibroblast growth factor 7
chr17_+_39346139 0.17 ENST00000398470.1
ENST00000318329.5
keratin associated protein 9-1
chr4_+_48492269 0.17 ENST00000327939.4
zygote arrest 1
chr3_-_52860850 0.17 ENST00000441637.2
inter-alpha-trypsin inhibitor heavy chain family, member 4
chr14_-_73493784 0.17 ENST00000553891.1
zinc finger, FYVE domain containing 1
chr17_-_41132010 0.16 ENST00000409103.1
ENST00000360221.4
PTGES3L-AARSD1 readthrough
chr15_+_67547113 0.16 ENST00000512104.1
ENST00000358767.3
ENST00000546225.1
IQ motif containing H
chr1_+_14075903 0.16 ENST00000343137.4
ENST00000503842.1
ENST00000407521.3
ENST00000505823.1
PR domain containing 2, with ZNF domain
chr11_-_62457371 0.16 ENST00000317449.4
LRRN4 C-terminal like
chr15_+_41186637 0.16 ENST00000558474.1
vacuolar protein sorting 18 homolog (S. cerevisiae)
chr21_+_17791838 0.16 ENST00000453910.1
long intergenic non-protein coding RNA 478
chr2_+_37311645 0.16 ENST00000281932.5
G patch domain containing 11
chr20_-_56195449 0.16 ENST00000541799.1
Z-DNA binding protein 1
chr11_-_117747327 0.16 ENST00000584230.1
ENST00000527429.1
ENST00000584394.1
ENST00000532984.1
FXYD domain containing ion transport regulator 6
FXYD6-FXYD2 readthrough
chr2_-_225811747 0.16 ENST00000409592.3
dedicator of cytokinesis 10
chr12_-_76879852 0.16 ENST00000548341.1
oxysterol binding protein-like 8
chr2_-_42180940 0.16 ENST00000378711.2
chromosome 2 open reading frame 91
chr12_-_56122426 0.16 ENST00000551173.1
CD63 molecule
chr6_+_41021027 0.15 ENST00000244669.2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
chr4_-_15661474 0.15 ENST00000509314.1
ENST00000503196.1
F-box and leucine-rich repeat protein 5
chr7_+_48128854 0.15 ENST00000436673.1
ENST00000429491.2
uridine phosphorylase 1
chr16_+_12059091 0.15 ENST00000562385.1
tumor necrosis factor receptor superfamily, member 17
chr4_+_159727272 0.15 ENST00000379346.3
folliculin interacting protein 2
chr6_-_133055896 0.15 ENST00000367927.5
ENST00000425515.2
ENST00000207771.3
ENST00000392393.3
ENST00000450865.2
ENST00000392394.2
vanin 3
chr2_+_85981008 0.15 ENST00000306279.3
atonal homolog 8 (Drosophila)
chr1_-_219615984 0.15 ENST00000420762.1
RP11-95P13.1
chr14_-_73493825 0.15 ENST00000318876.5
ENST00000556143.1
zinc finger, FYVE domain containing 1
chr22_+_17082732 0.15 ENST00000558085.2
ENST00000592918.1
ENST00000400593.2
ENST00000592107.1
ENST00000426585.1
ENST00000591299.1
transmembrane phosphatase with tensin homology pseudogene 1
chr13_-_41635512 0.15 ENST00000405737.2
E74-like factor 1 (ets domain transcription factor)
chr6_+_3259148 0.15 ENST00000419065.2
ENST00000473000.2
ENST00000451246.2
ENST00000454610.2
proteasome (prosome, macropain) assembly chaperone 4
chr14_+_23067166 0.15 ENST00000216327.6
ENST00000542041.1
abhydrolase domain containing 4
chr6_-_131211534 0.15 ENST00000456097.2
erythrocyte membrane protein band 4.1-like 2
chr22_+_31002779 0.14 ENST00000215838.3
transcobalamin II
chr22_+_31003133 0.14 ENST00000405742.3
transcobalamin II
chr16_-_30102547 0.14 ENST00000279386.2
T-box 6
chr10_-_69991865 0.14 ENST00000373673.3
atonal homolog 7 (Drosophila)
chr4_-_23735183 0.14 ENST00000507666.1
RP11-380P13.2
chr11_+_124933191 0.14 ENST00000532000.1
ENST00000308074.4
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr3_-_52868931 0.14 ENST00000486659.1
musculoskeletal, embryonic nuclear protein 1
chr20_+_33292068 0.14 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
tumor protein p53 inducible nuclear protein 2
chr2_-_69870747 0.14 ENST00000409068.1
AP2 associated kinase 1
chr11_+_6411636 0.14 ENST00000299397.3
ENST00000356761.2
ENST00000342245.4
sphingomyelin phosphodiesterase 1, acid lysosomal
chr16_-_79634595 0.14 ENST00000326043.4
ENST00000393350.1
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr17_-_8093471 0.14 ENST00000389017.4
chromosome 17 open reading frame 59
chr3_-_151176497 0.14 ENST00000282466.3
immunoglobulin superfamily, member 10
chr2_-_70409953 0.13 ENST00000419381.1
chromosome 2 open reading frame 42
chr7_+_48128816 0.13 ENST00000395564.4
uridine phosphorylase 1
chr17_-_7493390 0.13 ENST00000538513.2
ENST00000570788.1
ENST00000250055.2
SRY (sex determining region Y)-box 15
chr5_-_172755056 0.13 ENST00000520648.1
stanniocalcin 2
chr11_+_6411670 0.13 ENST00000530395.1
ENST00000527275.1
sphingomyelin phosphodiesterase 1, acid lysosomal
chr17_-_48133054 0.13 ENST00000499842.1
RP11-1094H24.4
chr1_-_42384343 0.13 ENST00000372584.1
human immunodeficiency virus type I enhancer binding protein 3
chr22_-_21580582 0.13 ENST00000424627.1
gamma-glutamyltransferase 2
chr1_+_12042015 0.13 ENST00000412236.1
mitofusin 2
chr8_-_135522425 0.12 ENST00000521673.1
zinc finger and AT hook domain containing
chr6_+_155334780 0.12 ENST00000538270.1
ENST00000535231.1
T-cell lymphoma invasion and metastasis 2
chr9_+_125796806 0.12 ENST00000373642.1
G protein-coupled receptor 21
chr10_-_100206642 0.12 ENST00000361490.4
ENST00000338546.5
ENST00000325103.6
Hermansky-Pudlak syndrome 1
chr2_-_176866978 0.12 ENST00000392540.2
ENST00000409660.1
ENST00000544803.1
ENST00000272748.4
KIAA1715
chr8_+_71581565 0.12 ENST00000408926.3
ENST00000520030.1
XK, Kell blood group complex subunit-related family, member 9
chr1_-_161014731 0.12 ENST00000368020.1
upstream transcription factor 1
chr8_+_107738240 0.12 ENST00000449762.2
ENST00000297447.6
oxidation resistance 1
chr4_-_46391367 0.12 ENST00000503806.1
ENST00000356504.1
ENST00000514090.1
ENST00000506961.1
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr10_-_106240032 0.12 ENST00000447860.1
RP11-127O4.3
chr17_+_1627834 0.12 ENST00000419248.1
ENST00000418841.1
WD repeat domain 81
chr11_+_71259466 0.12 ENST00000528743.2
keratin associated protein 5-9
chr11_-_624926 0.12 ENST00000526077.1
ENST00000534311.1
ENST00000531088.1
ENST00000397542.2
cadherin-related family member 5
chr14_-_67826538 0.12 ENST00000553687.1
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
chr17_+_7341586 0.11 ENST00000575235.1
fibroblast growth factor 11
chr19_+_18699599 0.11 ENST00000450195.2
chromosome 19 open reading frame 60
chr14_+_103388976 0.11 ENST00000299155.5
amnion associated transmembrane protein
chr7_+_48128316 0.11 ENST00000341253.4
uridine phosphorylase 1
chr11_+_124932986 0.11 ENST00000407458.1
ENST00000298280.5
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr5_+_95066823 0.11 ENST00000506817.1
ENST00000379982.3
Rho-related BTB domain containing 3
chr3_-_194119083 0.11 ENST00000401815.1
glycoprotein V (platelet)
chr6_+_155470243 0.11 ENST00000456877.2
ENST00000528391.2
T-cell lymphoma invasion and metastasis 2
chr21_+_30672433 0.11 ENST00000451655.1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr1_-_116926718 0.11 ENST00000598661.1
Uncharacterized protein
chr16_-_67427389 0.11 ENST00000562206.1
ENST00000290942.5
ENST00000393957.2
tubulin polymerization-promoting protein family member 3
chr1_-_33647267 0.11 ENST00000291416.5
tripartite motif containing 62
chr19_+_7587555 0.11 ENST00000601003.1
mucolipin 1
chr20_-_56195525 0.11 ENST00000371173.3
ENST00000395822.3
ENST00000340462.4
ENST00000343535.4
Z-DNA binding protein 1
chr12_-_54121261 0.11 ENST00000549784.1
ENST00000262059.4
calcium binding and coiled-coil domain 1
chr22_+_38071615 0.11 ENST00000215909.5
lectin, galactoside-binding, soluble, 1
chr19_+_57874835 0.11 ENST00000543226.1
ENST00000596755.1
ENST00000282282.3
ENST00000597658.1
trafficking protein particle complex 2 pseudogene 1
zinc finger protein 547
Uncharacterized protein
chr7_+_99699179 0.11 ENST00000438383.1
ENST00000429084.1
ENST00000359593.4
ENST00000439416.1
adaptor-related protein complex 4, mu 1 subunit
chr22_-_30814469 0.11 ENST00000598426.1
KIAA1658
chr17_+_42248063 0.11 ENST00000293414.1
ankyrin repeat and SOCS box containing 16
chr17_-_54893250 0.11 ENST00000397862.2
chromosome 17 open reading frame 67
chr2_-_61245363 0.11 ENST00000316752.6
pseudouridylate synthase 10
chr22_+_30792980 0.11 ENST00000403484.1
ENST00000405717.3
ENST00000402592.3
SEC14-like 2 (S. cerevisiae)
chr10_+_22605374 0.11 ENST00000448361.1
COMM domain containing 3
chr6_-_26250835 0.11 ENST00000446824.2
histone cluster 1, H3f
chr4_+_78079570 0.11 ENST00000509972.1
cyclin G2
chr1_+_223101757 0.11 ENST00000284476.6
dispatched homolog 1 (Drosophila)
chr14_+_53019993 0.10 ENST00000542169.2
ENST00000555622.1
G protein-coupled receptor 137C
chr10_+_1102721 0.10 ENST00000263150.4
WD repeat domain 37
chr20_-_50418947 0.10 ENST00000371539.3
spalt-like transcription factor 4
chr20_+_44098385 0.10 ENST00000217425.5
ENST00000339946.3
WAP four-disulfide core domain 2
chr7_+_18535893 0.10 ENST00000432645.2
ENST00000441542.2
histone deacetylase 9
chr16_-_18908196 0.10 ENST00000565324.1
ENST00000561947.1
SMG1 phosphatidylinositol 3-kinase-related kinase
chr8_-_27941380 0.10 ENST00000413272.2
ENST00000341513.6
nuclear GTPase, germinal center associated
chr4_+_165878100 0.10 ENST00000513876.2
family with sequence similarity 218, member A
chr17_+_6347729 0.10 ENST00000572447.1
family with sequence similarity 64, member A
chr3_+_159570722 0.10 ENST00000482804.1
schwannomin interacting protein 1
chr11_+_20044096 0.10 ENST00000533917.1
neuron navigator 2
chr8_+_86351056 0.10 ENST00000285381.2
carbonic anhydrase III, muscle specific
chr11_-_62323702 0.10 ENST00000530285.1
AHNAK nucleoprotein
chr19_-_8642289 0.10 ENST00000596675.1
ENST00000338257.8
myosin IF
chr8_+_81398444 0.10 ENST00000455036.3
ENST00000426744.2
zinc finger and BTB domain containing 10
chr2_-_37311445 0.10 ENST00000233099.5
ENST00000354531.2
HEAT repeat containing 5B
chr11_+_61722629 0.10 ENST00000526988.1
bestrophin 1
chr19_+_50191921 0.10 ENST00000420022.3
adrenomedullin 5 (putative)
chr14_-_53019211 0.10 ENST00000557374.1
ENST00000281741.4
thioredoxin domain containing 16
chr5_-_95158644 0.10 ENST00000237858.6
glutaredoxin (thioltransferase)
chr11_+_124932955 0.10 ENST00000403796.2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr1_-_153931052 0.10 ENST00000368630.3
ENST00000368633.1
CREB regulated transcription coactivator 2
chr8_-_67579418 0.09 ENST00000310421.4
valosin containing protein (p97)/p47 complex interacting protein 1
chr1_-_150669500 0.09 ENST00000271732.3
golgi phosphoprotein 3-like
chr17_-_21156578 0.09 ENST00000399011.2
ENST00000468196.1
chromosome 17 open reading frame 103
chr7_+_99699280 0.09 ENST00000421755.1
adaptor-related protein complex 4, mu 1 subunit
chr16_+_66914264 0.09 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr16_-_67514982 0.09 ENST00000565835.1
ENST00000540149.1
ENST00000290949.3
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr4_+_8183793 0.09 ENST00000509119.1
SH3 domain and tetratricopeptide repeats 1
chr15_+_75628232 0.09 ENST00000267935.8
ENST00000567195.1
COMM domain containing 4

Network of associatons between targets according to the STRING database.

First level regulatory network of TFAP4_MSC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.1 0.5 GO:0006218 uridine catabolic process(GO:0006218)
0.1 0.3 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.1 0.3 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.1 0.2 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.2 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.1 0.2 GO:0021571 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1 0.3 GO:1903028 positive regulation of opsonization(GO:1903028)
0.1 0.3 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.2 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.7 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.6 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.2 GO:0002086 diaphragm contraction(GO:0002086)
0.0 0.1 GO:0048627 myoblast development(GO:0048627)
0.0 0.2 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.0 0.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:0090675 intermicrovillar adhesion(GO:0090675)
0.0 0.0 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0016999 antibiotic metabolic process(GO:0016999)
0.0 0.2 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.3 GO:0023021 termination of signal transduction(GO:0023021)
0.0 0.2 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.3 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.3 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.4 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.1 GO:0070676 intralumenal vesicle formation(GO:0070676)
0.0 0.4 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.4 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.7 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.1 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 0.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.2 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.1 GO:0090156 cellular sphingolipid homeostasis(GO:0090156)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.2 GO:0098704 fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.1 GO:0090677 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.0 0.2 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.3 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.0 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.0 0.1 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.3 GO:0030238 male sex determination(GO:0030238)
0.0 0.1 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.0 0.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.3 GO:0015939 pantothenate metabolic process(GO:0015939)
0.0 0.1 GO:0002317 plasma cell differentiation(GO:0002317) response to isolation stress(GO:0035900)
0.0 0.1 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.3 GO:0021563 glossopharyngeal nerve development(GO:0021563)
0.0 0.1 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.1 GO:0019086 late viral transcription(GO:0019086)
0.0 0.1 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.2 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.1 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.0 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.0 GO:2000573 positive regulation of DNA biosynthetic process(GO:2000573)
0.0 0.1 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.1 GO:0006788 heme oxidation(GO:0006788) negative regulation of mast cell cytokine production(GO:0032764)
0.0 0.0 GO:0021650 vestibulocochlear nerve formation(GO:0021650)
0.0 0.6 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.0 GO:0031662 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.0 0.1 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.0 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.1 GO:1903285 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.0 0.1 GO:1904970 brush border assembly(GO:1904970)
0.0 0.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.2 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0 0.1 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.1 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.0 GO:0043324 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.1 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.1 GO:1903401 L-lysine transmembrane transport(GO:1903401)
0.0 0.1 GO:0036115 fatty-acyl-CoA catabolic process(GO:0036115)
0.0 0.0 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.0 0.1 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.1 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:0038183 bile acid signaling pathway(GO:0038183)
0.0 0.2 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.4 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.1 GO:0021554 optic nerve development(GO:0021554)
0.0 0.1 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.4 GO:0031581 hemidesmosome assembly(GO:0031581)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.3 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 0.5 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.3 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 1.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.1 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.4 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.2 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.4 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.0 0.2 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.0 GO:0072534 perineuronal net(GO:0072534)
0.0 0.3 GO:0042599 lamellar body(GO:0042599)
0.0 0.2 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 1.2 GO:0016459 myosin complex(GO:0016459)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.1 0.3 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.1 0.5 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.1 0.4 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.1 0.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.2 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.1 0.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.2 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.4 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.3 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0030395 lactose binding(GO:0030395)
0.0 1.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0052594 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.1 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.0 0.2 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.2 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.1 GO:0070984 SET domain binding(GO:0070984)
0.0 0.1 GO:0072545 tyrosine binding(GO:0072545)
0.0 0.1 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.3 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.4 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.4 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.5 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.3 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.5 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.3 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)