Project
A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
Navigation
Downloads
Results for TFAP2C
Z-value: 1.34
Motif logo
Transcription factors associated with TFAP2C
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| TFAP2C | hg19_v2_chr20_+_55205825_55205938 | 0.61 | 2.0e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr2_+_74212073 Show fit | 0.88 |
ENST00000441217.1
|
AC073046.25 |
|
| chr12_-_53207842 Show fit | 0.70 |
ENST00000458244.2
|
keratin 4 |
|
| chr19_-_55628927 Show fit | 0.68 |
ENST00000263433.3
ENST00000376393.2 |
protein phosphatase 1, regulatory subunit 12C |
|
| chr19_+_51815102 Show fit | 0.67 |
ENST00000270642.8
|
IgLON family member 5 |
|
| chrX_-_16888276 Show fit | 0.66 |
ENST00000493145.1
|
retinoblastoma binding protein 7 |
|
| chr16_+_84002234 Show fit | 0.62 |
ENST00000305202.4
|
N-terminal EF-hand calcium binding protein 2 |
|
| chr10_+_88728189 Show fit | 0.62 |
ENST00000416348.1
|
adipogenesis regulatory factor |
|
| chr2_+_206950095 Show fit | 0.57 |
ENST00000435627.1
|
AC007383.3 |
|
| chr2_-_45165994 Show fit | 0.57 |
ENST00000444871.2
|
RP11-89K21.1 |
|
| chr17_+_79859985 Show fit | 0.56 |
ENST00000333383.7
|
neuropeptide B |
Network of associatons between targets according to the STRING database.
First level regulatory network of TFAP2C
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.0 | 1.2 | GO:0031338 | regulation of vesicle fusion(GO:0031338) |
| 0.2 | 1.1 | GO:0060167 | regulation of adenosine receptor signaling pathway(GO:0060167) |
| 0.0 | 1.1 | GO:0033572 | transferrin transport(GO:0033572) |
| 0.0 | 0.9 | GO:0031581 | hemidesmosome assembly(GO:0031581) |
| 0.1 | 0.8 | GO:0030423 | targeting of mRNA for destruction involved in RNA interference(GO:0030423) |
| 0.1 | 0.8 | GO:0044341 | sodium-dependent phosphate transport(GO:0044341) |
| 0.0 | 0.8 | GO:0090292 | nuclear matrix anchoring at nuclear membrane(GO:0090292) |
| 0.0 | 0.8 | GO:0007250 | activation of NF-kappaB-inducing kinase activity(GO:0007250) |
| 0.0 | 0.8 | GO:0007257 | activation of JUN kinase activity(GO:0007257) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.4 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.0 | 1.4 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.0 | 1.3 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.1 | 1.1 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
| 0.1 | 0.9 | GO:0098560 | cytoplasmic side of late endosome membrane(GO:0098560) |
| 0.0 | 0.9 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.0 | 0.8 | GO:0034992 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.0 | 0.8 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.0 | 0.8 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.1 | 0.7 | GO:0005642 | annulate lamellae(GO:0005642) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.0 | 1.2 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.0 | 1.2 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.0 | 1.2 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.0 | 1.1 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 1.0 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.0 | 1.0 | GO:0005521 | lamin binding(GO:0005521) |
| 0.1 | 0.9 | GO:0043141 | ATP-dependent 5'-3' DNA helicase activity(GO:0043141) |
| 0.1 | 0.9 | GO:0048495 | Roundabout binding(GO:0048495) |
| 0.1 | 0.9 | GO:0070883 | pre-miRNA binding(GO:0070883) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.1 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.0 | 1.6 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.0 | 1.4 | ST B CELL ANTIGEN RECEPTOR | B Cell Antigen Receptor |
| 0.0 | 1.2 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.0 | 1.0 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.0 | 1.0 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.0 | 1.0 | PID BMP PATHWAY | BMP receptor signaling |
| 0.0 | 1.0 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.0 | 0.9 | ST P38 MAPK PATHWAY | p38 MAPK Pathway |
| 0.0 | 0.9 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.4 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.0 | 1.3 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.0 | 1.2 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.0 | 1.0 | REACTOME HS GAG DEGRADATION | Genes involved in HS-GAG degradation |
| 0.0 | 0.9 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.1 | 0.8 | REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT | Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat |
| 0.0 | 0.8 | REACTOME DESTABILIZATION OF MRNA BY BRF1 | Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1) |
| 0.0 | 0.8 | REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
| 0.0 | 0.8 | REACTOME MICRORNA MIRNA BIOGENESIS | Genes involved in MicroRNA (miRNA) Biogenesis |
| 0.0 | 0.8 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |