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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TCF7L2

Z-value: 0.54

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Transcription factors associated with TCF7L2

Gene Symbol Gene ID Gene Info
TCF7L2
ENSG00000148737.11 transcription factor 7 like 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF7L2hg19_v2_chr10_+_114709999_114710031-0.805.4e-02Click!

Activity profile of TCF7L2 motif

Sorted Z-values of TCF7L2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_63557309 0.50 ENST00000580513.1
AXIN2
axin 2
chr1_-_219615984 0.34 ENST00000420762.1
RP11-95P13.1
RP11-95P13.1
chr13_+_76334498 0.31 ENST00000534657.1
LMO7
LIM domain 7
chr4_+_183065793 0.30 ENST00000512480.1
TENM3
teneurin transmembrane protein 3
chr10_-_14613968 0.29 ENST00000488576.1
ENST00000472095.1
FAM107B
family with sequence similarity 107, member B
chr18_+_46065570 0.27 ENST00000591412.1
CTIF
CBP80/20-dependent translation initiation factor
chr4_+_87857538 0.25 ENST00000511442.1
AFF1
AF4/FMR2 family, member 1
chr18_+_19668021 0.24 ENST00000579830.1
RP11-595B24.2
Uncharacterized protein
chr9_+_97766409 0.24 ENST00000425634.2
C9orf3
chromosome 9 open reading frame 3
chr10_-_14614311 0.24 ENST00000479731.1
ENST00000468492.1
FAM107B
family with sequence similarity 107, member B
chr10_-_75351088 0.23 ENST00000451492.1
ENST00000413442.1
USP54
ubiquitin specific peptidase 54
chr9_+_97766469 0.22 ENST00000433691.2
C9orf3
chromosome 9 open reading frame 3
chr19_-_44008863 0.21 ENST00000601646.1
PHLDB3
pleckstrin homology-like domain, family B, member 3
chr11_-_75921780 0.21 ENST00000529461.1
WNT11
wingless-type MMTV integration site family, member 11
chr7_-_75452673 0.20 ENST00000416943.1
CCL24
chemokine (C-C motif) ligand 24
chr11_-_76155618 0.20 ENST00000530759.1
RP11-111M22.3
RP11-111M22.3
chr5_+_133450365 0.18 ENST00000342854.5
ENST00000321603.6
ENST00000321584.4
ENST00000378564.1
ENST00000395029.1
TCF7
transcription factor 7 (T-cell specific, HMG-box)
chr1_-_11907829 0.17 ENST00000376480.3
NPPA
natriuretic peptide A
chr10_-_104192405 0.17 ENST00000369937.4
CUEDC2
CUE domain containing 2
chr3_-_134093395 0.17 ENST00000249883.5
AMOTL2
angiomotin like 2
chr5_+_102200948 0.16 ENST00000511477.1
ENST00000506006.1
ENST00000509832.1
PAM
peptidylglycine alpha-amidating monooxygenase
chr10_-_14614095 0.14 ENST00000482277.1
ENST00000378462.1
FAM107B
family with sequence similarity 107, member B
chr10_+_7745303 0.14 ENST00000429820.1
ENST00000379587.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr17_+_1674982 0.14 ENST00000572048.1
ENST00000573763.1
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr15_-_90294523 0.14 ENST00000300057.4
MESP1
mesoderm posterior 1 homolog (mouse)
chr5_+_170846640 0.13 ENST00000274625.5
FGF18
fibroblast growth factor 18
chr16_+_53242350 0.13 ENST00000565442.1
CHD9
chromodomain helicase DNA binding protein 9
chr3_-_134093275 0.13 ENST00000513145.1
ENST00000422605.2
AMOTL2
angiomotin like 2
chr4_-_146859623 0.13 ENST00000379448.4
ENST00000513320.1
ZNF827
zinc finger protein 827
chr10_+_7745232 0.13 ENST00000358415.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr10_-_14614122 0.13 ENST00000378465.3
ENST00000452706.2
ENST00000378458.2
FAM107B
family with sequence similarity 107, member B
chr14_+_62037287 0.13 ENST00000556569.1
RP11-47I22.3
Uncharacterized protein
chr11_+_45944190 0.13 ENST00000401752.1
ENST00000389968.3
ENST00000325468.5
ENST00000536139.1
GYLTL1B
glycosyltransferase-like 1B
chrX_-_19765692 0.12 ENST00000432234.1
SH3KBP1
SH3-domain kinase binding protein 1
chr17_+_34848049 0.12 ENST00000588902.1
ENST00000591067.1
ZNHIT3
zinc finger, HIT-type containing 3
chr14_+_68189190 0.12 ENST00000539142.1
RDH12
retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
chr13_-_30160925 0.12 ENST00000450494.1
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr5_-_16742330 0.12 ENST00000505695.1
ENST00000427430.2
MYO10
myosin X
chr17_-_73389854 0.11 ENST00000578961.1
ENST00000392564.1
ENST00000582582.1
GRB2
growth factor receptor-bound protein 2
chr22_-_33968239 0.11 ENST00000452586.2
ENST00000421768.1
LARGE
like-glycosyltransferase
chr14_-_23762777 0.11 ENST00000431326.2
HOMEZ
homeobox and leucine zipper encoding
chr3_-_134093738 0.11 ENST00000506107.1
AMOTL2
angiomotin like 2
chr11_+_114128522 0.11 ENST00000535401.1
NNMT
nicotinamide N-methyltransferase
chr12_+_85673868 0.11 ENST00000316824.3
ALX1
ALX homeobox 1
chr17_-_38256973 0.11 ENST00000246672.3
NR1D1
nuclear receptor subfamily 1, group D, member 1
chr8_-_16859690 0.10 ENST00000180166.5
FGF20
fibroblast growth factor 20
chr12_-_133464151 0.10 ENST00000315585.7
ENST00000266880.7
ENST00000443047.2
ENST00000432561.2
ENST00000450056.2
CHFR
checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
chr19_+_50084561 0.10 ENST00000246794.5
PRRG2
proline rich Gla (G-carboxyglutamic acid) 2
chr2_+_228678550 0.10 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr1_-_109935819 0.10 ENST00000538502.1
SORT1
sortilin 1
chr16_+_19222479 0.09 ENST00000568433.1
SYT17
synaptotagmin XVII
chr16_-_73082274 0.09 ENST00000268489.5
ZFHX3
zinc finger homeobox 3
chr1_+_61330931 0.09 ENST00000371191.1
NFIA
nuclear factor I/A
chr22_+_19950060 0.09 ENST00000449653.1
COMT
catechol-O-methyltransferase
chr17_+_75447326 0.09 ENST00000591088.1
SEPT9
septin 9
chr17_-_40169659 0.09 ENST00000457167.4
DNAJC7
DnaJ (Hsp40) homolog, subfamily C, member 7
chr5_+_102201430 0.09 ENST00000438793.3
ENST00000346918.2
PAM
peptidylglycine alpha-amidating monooxygenase
chr16_+_50582222 0.08 ENST00000268459.3
NKD1
naked cuticle homolog 1 (Drosophila)
chr11_+_65408273 0.08 ENST00000394227.3
SIPA1
signal-induced proliferation-associated 1
chr6_-_28220002 0.08 ENST00000377294.2
ZKSCAN4
zinc finger with KRAB and SCAN domains 4
chr1_-_40367668 0.08 ENST00000397332.2
ENST00000429311.1
MYCL
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
chr13_+_76334795 0.08 ENST00000526202.1
ENST00000465261.2
LMO7
LIM domain 7
chr7_-_148725733 0.08 ENST00000286091.4
PDIA4
protein disulfide isomerase family A, member 4
chr4_-_69215699 0.08 ENST00000510746.1
ENST00000344157.4
ENST00000355665.3
YTHDC1
YTH domain containing 1
chr17_-_63557759 0.08 ENST00000307078.5
AXIN2
axin 2
chr13_+_76334567 0.08 ENST00000321797.8
LMO7
LIM domain 7
chr7_+_73868439 0.07 ENST00000424337.2
GTF2IRD1
GTF2I repeat domain containing 1
chr14_+_75230011 0.07 ENST00000552421.1
ENST00000325680.7
ENST00000238571.3
YLPM1
YLP motif containing 1
chr10_+_54074033 0.07 ENST00000373970.3
DKK1
dickkopf WNT signaling pathway inhibitor 1
chr8_+_29953163 0.07 ENST00000518192.1
LEPROTL1
leptin receptor overlapping transcript-like 1
chr6_-_11779840 0.07 ENST00000506810.1
ADTRP
androgen-dependent TFPI-regulating protein
chr9_-_32635667 0.07 ENST00000242310.4
TAF1L
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 210kDa-like
chr12_+_6982725 0.07 ENST00000433346.1
LRRC23
leucine rich repeat containing 23
chr2_+_69240415 0.07 ENST00000409829.3
ANTXR1
anthrax toxin receptor 1
chr2_+_69240511 0.07 ENST00000409349.3
ANTXR1
anthrax toxin receptor 1
chr11_+_7597639 0.07 ENST00000533792.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr5_-_135290705 0.07 ENST00000274507.1
LECT2
leukocyte cell-derived chemotaxin 2
chr17_-_39316983 0.07 ENST00000390661.3
KRTAP4-4
keratin associated protein 4-4
chr4_-_157892055 0.06 ENST00000422544.2
PDGFC
platelet derived growth factor C
chr6_-_32145861 0.06 ENST00000336984.6
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr5_-_16936340 0.06 ENST00000507288.1
ENST00000513610.1
MYO10
myosin X
chr2_+_47168630 0.06 ENST00000263737.6
TTC7A
tetratricopeptide repeat domain 7A
chr7_-_27219849 0.06 ENST00000396344.4
HOXA10
homeobox A10
chr10_-_105677427 0.06 ENST00000369764.1
OBFC1
oligonucleotide/oligosaccharide-binding fold containing 1
chr17_-_46035187 0.06 ENST00000300557.2
PRR15L
proline rich 15-like
chr9_-_15510287 0.06 ENST00000397519.2
PSIP1
PC4 and SFRS1 interacting protein 1
chr2_+_177028805 0.06 ENST00000249440.3
HOXD3
homeobox D3
chr5_+_60628074 0.06 ENST00000252744.5
ZSWIM6
zinc finger, SWIM-type containing 6
chr6_-_135424186 0.06 ENST00000529882.1
HBS1L
HBS1-like (S. cerevisiae)
chr4_+_86525299 0.06 ENST00000512201.1
ARHGAP24
Rho GTPase activating protein 24
chr2_+_11679963 0.06 ENST00000263834.5
GREB1
growth regulation by estrogen in breast cancer 1
chr3_+_57875711 0.06 ENST00000442599.2
SLMAP
sarcolemma associated protein
chr4_+_95972822 0.05 ENST00000509540.1
ENST00000440890.2
BMPR1B
bone morphogenetic protein receptor, type IB
chr1_-_166028709 0.05 ENST00000595430.1
AL626787.1
AL626787.1
chr4_+_170581213 0.05 ENST00000507875.1
CLCN3
chloride channel, voltage-sensitive 3
chr5_-_160973649 0.05 ENST00000393959.1
ENST00000517547.1
GABRB2
gamma-aminobutyric acid (GABA) A receptor, beta 2
chrX_-_39956656 0.05 ENST00000397354.3
ENST00000378444.4
BCOR
BCL6 corepressor
chr5_+_175288631 0.05 ENST00000509837.1
CPLX2
complexin 2
chr1_-_115053781 0.05 ENST00000358465.2
ENST00000369543.2
TRIM33
tripartite motif containing 33
chr1_+_151138526 0.05 ENST00000368902.1
SCNM1
sodium channel modifier 1
chr2_+_171571827 0.05 ENST00000375281.3
SP5
Sp5 transcription factor
chr11_-_62474803 0.05 ENST00000533982.1
ENST00000360796.5
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr12_+_54694979 0.05 ENST00000552848.1
COPZ1
coatomer protein complex, subunit zeta 1
chr1_-_110933663 0.05 ENST00000369781.4
ENST00000541986.1
ENST00000369779.4
SLC16A4
solute carrier family 16, member 4
chr17_+_80818231 0.05 ENST00000576996.1
TBCD
tubulin folding cofactor D
chr8_+_55467072 0.05 ENST00000602362.1
RP11-53M11.3
RP11-53M11.3
chr2_-_9143786 0.05 ENST00000462696.1
ENST00000305997.3
MBOAT2
membrane bound O-acyltransferase domain containing 2
chr3_+_57875738 0.05 ENST00000417128.1
ENST00000438794.1
SLMAP
sarcolemma associated protein
chrX_+_47004639 0.04 ENST00000345781.6
RBM10
RNA binding motif protein 10
chr3_-_33686925 0.04 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2
cytoplasmic linker associated protein 2
chr7_+_80275953 0.04 ENST00000538969.1
ENST00000544133.1
ENST00000433696.2
CD36
CD36 molecule (thrombospondin receptor)
chr3_-_79068138 0.04 ENST00000495273.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr19_-_40791211 0.04 ENST00000579047.1
AKT2
v-akt murine thymoma viral oncogene homolog 2
chr3_+_29323043 0.04 ENST00000452462.1
ENST00000456853.1
RBMS3
RNA binding motif, single stranded interacting protein 3
chr18_+_46065393 0.04 ENST00000256413.3
CTIF
CBP80/20-dependent translation initiation factor
chr4_-_146859787 0.04 ENST00000508784.1
ZNF827
zinc finger protein 827
chr7_-_148581251 0.04 ENST00000478654.1
ENST00000460911.1
ENST00000350995.2
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr5_-_153857819 0.04 ENST00000231121.2
HAND1
heart and neural crest derivatives expressed 1
chr7_+_27282319 0.04 ENST00000222761.3
EVX1
even-skipped homeobox 1
chr2_+_173724771 0.04 ENST00000538974.1
ENST00000540783.1
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chrX_-_100183894 0.04 ENST00000328526.5
ENST00000372956.2
XKRX
XK, Kell blood group complex subunit-related, X-linked
chr6_-_24645956 0.04 ENST00000543707.1
KIAA0319
KIAA0319
chr6_+_152130240 0.04 ENST00000427531.2
ESR1
estrogen receptor 1
chr9_+_128510454 0.04 ENST00000491787.3
ENST00000447726.2
PBX3
pre-B-cell leukemia homeobox 3
chr17_-_7297519 0.04 ENST00000576362.1
ENST00000571078.1
TMEM256-PLSCR3
TMEM256-PLSCR3 readthrough (NMD candidate)
chrX_+_47004599 0.04 ENST00000329236.7
RBM10
RNA binding motif protein 10
chr1_+_162351503 0.03 ENST00000458626.2
C1orf226
chromosome 1 open reading frame 226
chr6_-_11779403 0.03 ENST00000414691.3
ADTRP
androgen-dependent TFPI-regulating protein
chr10_-_101380121 0.03 ENST00000370495.4
SLC25A28
solute carrier family 25 (mitochondrial iron transporter), member 28
chrX_+_2670066 0.03 ENST00000381174.5
ENST00000419513.2
ENST00000426774.1
XG
Xg blood group
chr1_+_223101757 0.03 ENST00000284476.6
DISP1
dispatched homolog 1 (Drosophila)
chr20_-_656437 0.03 ENST00000488788.2
RP5-850E9.3
Uncharacterized protein
chr17_+_79679299 0.03 ENST00000331531.5
SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr2_-_80531399 0.03 ENST00000409148.1
ENST00000415098.1
ENST00000452811.1
LRRTM1
leucine rich repeat transmembrane neuronal 1
chr17_+_48611853 0.03 ENST00000507709.1
ENST00000515126.1
ENST00000507467.1
EPN3
epsin 3
chr14_-_81425828 0.03 ENST00000555529.1
ENST00000556042.1
ENST00000556981.1
CEP128
centrosomal protein 128kDa
chr7_-_16505440 0.03 ENST00000307068.4
SOSTDC1
sclerostin domain containing 1
chr15_-_65670360 0.03 ENST00000327987.4
IGDCC3
immunoglobulin superfamily, DCC subclass, member 3
chr6_-_112575758 0.03 ENST00000431543.2
ENST00000453937.2
ENST00000368638.4
ENST00000389463.4
LAMA4
laminin, alpha 4
chr4_-_109684120 0.03 ENST00000512646.1
ENST00000411864.2
ENST00000296486.3
ENST00000510706.1
ETNPPL
ethanolamine-phosphate phospho-lyase
chrX_+_100646190 0.03 ENST00000471855.1
RPL36A
ribosomal protein L36a
chr11_-_62572901 0.03 ENST00000439713.2
ENST00000531131.1
ENST00000530875.1
ENST00000531709.2
ENST00000294172.2
NXF1
nuclear RNA export factor 1
chr17_+_42923686 0.03 ENST00000591513.1
HIGD1B
HIG1 hypoxia inducible domain family, member 1B
chr1_+_62417957 0.03 ENST00000307297.7
ENST00000543708.1
INADL
InaD-like (Drosophila)
chr17_-_56065540 0.03 ENST00000583932.1
VEZF1
vascular endothelial zinc finger 1
chr7_+_80275752 0.03 ENST00000419819.2
CD36
CD36 molecule (thrombospondin receptor)
chr7_-_105926058 0.03 ENST00000417537.1
NAMPT
nicotinamide phosphoribosyltransferase
chr8_-_142012169 0.03 ENST00000517453.1
PTK2
protein tyrosine kinase 2
chr14_-_21502944 0.03 ENST00000382951.3
RNASE13
ribonuclease, RNase A family, 13 (non-active)
chr17_-_73389737 0.03 ENST00000392563.1
GRB2
growth factor receptor-bound protein 2
chr11_-_6677018 0.03 ENST00000299441.3
DCHS1
dachsous cadherin-related 1
chrX_+_100645812 0.03 ENST00000427805.2
ENST00000553110.3
ENST00000392994.3
ENST00000409338.1
ENST00000409170.3
RPL36A
RPL36A-HNRNPH2
ribosomal protein L36a
RPL36A-HNRNPH2 readthrough
chr2_+_201936458 0.03 ENST00000237889.4
NDUFB3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa
chr17_-_7297833 0.03 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
TMEM256-PLSCR3
TMEM256-PLSCR3 readthrough (NMD candidate)
chr1_-_161993616 0.03 ENST00000294794.3
OLFML2B
olfactomedin-like 2B
chr1_+_147013182 0.03 ENST00000234739.3
BCL9
B-cell CLL/lymphoma 9
chr9_+_139221880 0.03 ENST00000392945.3
ENST00000440944.1
GPSM1
G-protein signaling modulator 1
chr6_+_35704855 0.02 ENST00000288065.2
ENST00000373866.3
ARMC12
armadillo repeat containing 12
chr11_-_94965667 0.02 ENST00000542176.1
ENST00000278499.2
SESN3
sestrin 3
chr14_-_75179774 0.02 ENST00000555249.1
ENST00000556202.1
ENST00000356357.4
ENST00000338772.5
AREL1
AC007956.1
apoptosis resistant E3 ubiquitin protein ligase 1
Full-length cDNA 5-PRIME end of clone CS0CAP004YO05 of Thymus of Homo sapiens (human); Uncharacterized protein
chr18_-_24445664 0.02 ENST00000578776.1
AQP4
aquaporin 4
chr1_+_16693578 0.02 ENST00000401088.4
ENST00000471507.1
ENST00000401089.3
ENST00000375590.3
ENST00000492354.1
SZRD1
SUZ RNA binding domain containing 1
chr1_-_94079648 0.02 ENST00000370247.3
BCAR3
breast cancer anti-estrogen resistance 3
chr17_+_37618257 0.02 ENST00000447079.4
CDK12
cyclin-dependent kinase 12
chr15_+_90744745 0.02 ENST00000558051.1
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr6_-_11779174 0.02 ENST00000379413.2
ADTRP
androgen-dependent TFPI-regulating protein
chr14_+_32798462 0.02 ENST00000280979.4
AKAP6
A kinase (PRKA) anchor protein 6
chr7_-_148581360 0.02 ENST00000320356.2
ENST00000541220.1
ENST00000483967.1
ENST00000536783.1
EZH2
enhancer of zeste homolog 2 (Drosophila)
chr3_+_155838337 0.02 ENST00000490337.1
ENST00000389636.5
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr15_+_96897466 0.02 ENST00000558382.1
ENST00000558499.1
RP11-522B15.3
RP11-522B15.3
chrX_+_106163626 0.02 ENST00000336803.1
CLDN2
claudin 2
chr17_-_56065484 0.02 ENST00000581208.1
VEZF1
vascular endothelial zinc finger 1
chr12_-_31477072 0.02 ENST00000454658.2
FAM60A
family with sequence similarity 60, member A
chr6_+_64281906 0.02 ENST00000370651.3
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr5_+_102201509 0.02 ENST00000348126.2
ENST00000379787.4
PAM
peptidylglycine alpha-amidating monooxygenase
chr1_+_154244987 0.02 ENST00000328703.7
ENST00000457918.2
ENST00000483970.2
ENST00000435087.1
ENST00000532105.1
HAX1
HCLS1 associated protein X-1
chr11_-_76155700 0.02 ENST00000572035.1
RP11-111M22.3
RP11-111M22.3
chr17_-_39123144 0.02 ENST00000355612.2
KRT39
keratin 39
chr3_-_33686743 0.02 ENST00000333778.6
ENST00000539981.1
CLASP2
cytoplasmic linker associated protein 2
chr9_-_23826298 0.02 ENST00000380117.1
ELAVL2
ELAV like neuron-specific RNA binding protein 2
chr2_+_69240302 0.02 ENST00000303714.4
ANTXR1
anthrax toxin receptor 1
chr17_-_39093672 0.02 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
KRT23
keratin 23 (histone deacetylase inducible)
chr12_+_70760056 0.02 ENST00000258111.4
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr7_-_27213893 0.02 ENST00000283921.4
HOXA10
homeobox A10
chr15_+_57511609 0.02 ENST00000543579.1
ENST00000537840.1
ENST00000343827.3
TCF12
transcription factor 12
chr8_+_32579341 0.02 ENST00000519240.1
ENST00000539990.1
NRG1
neuregulin 1
chr15_+_43985084 0.02 ENST00000434505.1
ENST00000411750.1
CKMT1A
creatine kinase, mitochondrial 1A
chr20_+_30555805 0.02 ENST00000562532.2
XKR7
XK, Kell blood group complex subunit-related family, member 7
chr3_-_149375783 0.02 ENST00000467467.1
ENST00000460517.1
ENST00000360632.3
WWTR1
WW domain containing transcription regulator 1
chr10_+_114710516 0.02 ENST00000542695.1
ENST00000346198.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr5_+_140235469 0.02 ENST00000506939.2
ENST00000307360.5
PCDHA10
protocadherin alpha 10
chr7_+_99613212 0.01 ENST00000426572.1
ENST00000535170.1
ZKSCAN1
zinc finger with KRAB and SCAN domains 1
chr22_+_29279552 0.01 ENST00000544604.2
ZNRF3
zinc and ring finger 3
chr5_+_66300446 0.01 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr5_-_175815565 0.01 ENST00000509257.1
ENST00000507413.1
ENST00000510123.1
NOP16
NOP16 nucleolar protein
chr6_-_112575838 0.01 ENST00000455073.1
LAMA4
laminin, alpha 4
chr6_-_112575687 0.01 ENST00000521398.1
ENST00000424408.2
ENST00000243219.3
LAMA4
laminin, alpha 4
chr12_+_80603233 0.01 ENST00000547103.1
ENST00000458043.2
OTOGL
otogelin-like
chr3_+_141106643 0.01 ENST00000514251.1
ZBTB38
zinc finger and BTB domain containing 38
chr6_+_37137939 0.01 ENST00000373509.5
PIM1
pim-1 oncogene

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF7L2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.1 0.2 GO:0100012 negative regulation of mesodermal cell fate specification(GO:0042662) regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012)
0.1 0.2 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.1 0.2 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.0 0.3 GO:0018032 protein amidation(GO:0018032)
0.0 0.1 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.0 0.2 GO:1902304 positive regulation of potassium ion export(GO:1902304)
0.0 0.1 GO:0045360 interleukin-1 biosynthetic process(GO:0042222) regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.0 0.2 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.2 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.2 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.1 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.0 0.1 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.0 0.1 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.1 GO:0031337 cellular response to phosphate starvation(GO:0016036) regulation of sulfur amino acid metabolic process(GO:0031335) positive regulation of sulfur amino acid metabolic process(GO:0031337) regulation of homocysteine metabolic process(GO:0050666) positive regulation of homocysteine metabolic process(GO:0050668)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0042631 cellular response to water deprivation(GO:0042631)
0.0 0.1 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.1 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.0 0.1 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.1 GO:1903826 arginine transmembrane transport(GO:1903826)
0.0 0.0 GO:0003192 mitral valve formation(GO:0003192)
0.0 0.3 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.0 GO:0007387 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.0 0.0 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.1 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.0 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.0 GO:0071423 thiosulfate transport(GO:0015709) oxaloacetate transport(GO:0015729) malate transport(GO:0015743) malate transmembrane transport(GO:0071423) oxaloacetate(2-) transmembrane transport(GO:1902356)
0.0 0.0 GO:0003219 cardiac right ventricle formation(GO:0003219)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.4 GO:0030877 beta-catenin destruction complex(GO:0030877)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.0 0.3 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.1 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.0 0.1 GO:0008112 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.5 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.1 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.0 GO:0015117 thiosulfate transmembrane transporter activity(GO:0015117) oxaloacetate transmembrane transporter activity(GO:0015131)
0.0 0.1 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.0 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants