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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TCF7L1

Z-value: 0.76

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Transcription factors associated with TCF7L1

Gene Symbol Gene ID Gene Info
TCF7L1
ENSG00000152284.4 transcription factor 7 like 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF7L1hg19_v2_chr2_+_85360499_853605980.216.9e-01Click!

Activity profile of TCF7L1 motif

Sorted Z-values of TCF7L1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_63557309 1.02 ENST00000580513.1
AXIN2
axin 2
chr17_-_63556414 0.82 ENST00000585045.1
AXIN2
axin 2
chr15_+_96897466 0.53 ENST00000558382.1
ENST00000558499.1
RP11-522B15.3
RP11-522B15.3
chr6_-_32083106 0.46 ENST00000442721.1
TNXB
tenascin XB
chr2_+_228678550 0.46 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr8_-_128231299 0.41 ENST00000500112.1
CCAT1
colon cancer associated transcript 1 (non-protein coding)
chr1_+_53793885 0.41 ENST00000445039.2
RP4-784A16.5
RP4-784A16.5
chr8_+_32579271 0.40 ENST00000518084.1
NRG1
neuregulin 1
chr14_-_71107921 0.37 ENST00000553982.1
ENST00000500016.1
CTD-2540L5.5
CTD-2540L5.6
CTD-2540L5.5
CTD-2540L5.6
chr5_-_114515734 0.36 ENST00000514154.1
ENST00000282369.3
TRIM36
tripartite motif containing 36
chr2_+_220309379 0.35 ENST00000451076.1
SPEG
SPEG complex locus
chr12_+_28605426 0.34 ENST00000542801.1
CCDC91
coiled-coil domain containing 91
chr3_-_148939835 0.34 ENST00000264613.6
CP
ceruloplasmin (ferroxidase)
chr10_+_54074033 0.33 ENST00000373970.3
DKK1
dickkopf WNT signaling pathway inhibitor 1
chr8_+_22019168 0.32 ENST00000318561.3
ENST00000521315.1
ENST00000437090.2
ENST00000520605.1
ENST00000522109.1
ENST00000524255.1
ENST00000523296.1
ENST00000518615.1
SFTPC
surfactant protein C
chr6_-_27440460 0.30 ENST00000377419.1
ZNF184
zinc finger protein 184
chr3_-_148939598 0.30 ENST00000455472.3
CP
ceruloplasmin (ferroxidase)
chr8_-_42358742 0.30 ENST00000517366.1
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr6_-_135424186 0.29 ENST00000529882.1
HBS1L
HBS1-like (S. cerevisiae)
chr4_+_79567362 0.29 ENST00000512322.1
RP11-792D21.2
long intergenic non-protein coding RNA 1094
chr12_+_70760056 0.29 ENST00000258111.4
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr15_+_43885252 0.28 ENST00000453782.1
ENST00000300283.6
ENST00000437924.1
ENST00000450086.2
CKMT1B
creatine kinase, mitochondrial 1B
chr4_+_79567057 0.27 ENST00000503259.1
ENST00000507802.1
RP11-792D21.2
long intergenic non-protein coding RNA 1094
chr12_+_9066472 0.27 ENST00000538657.1
PHC1
polyhomeotic homolog 1 (Drosophila)
chr1_+_93645314 0.27 ENST00000343253.7
CCDC18
coiled-coil domain containing 18
chr17_+_59529743 0.27 ENST00000589003.1
ENST00000393853.4
TBX4
T-box 4
chr5_+_102201430 0.26 ENST00000438793.3
ENST00000346918.2
PAM
peptidylglycine alpha-amidating monooxygenase
chr4_-_157892055 0.26 ENST00000422544.2
PDGFC
platelet derived growth factor C
chr2_+_171571827 0.25 ENST00000375281.3
SP5
Sp5 transcription factor
chr12_-_108154705 0.25 ENST00000547188.1
PRDM4
PR domain containing 4
chr8_+_55467072 0.25 ENST00000602362.1
RP11-53M11.3
RP11-53M11.3
chr4_-_103266219 0.25 ENST00000394833.2
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr21_+_30671690 0.24 ENST00000399921.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr17_+_9066252 0.24 ENST00000436734.1
NTN1
netrin 1
chr8_+_17104401 0.24 ENST00000324815.3
ENST00000518038.1
VPS37A
vacuolar protein sorting 37 homolog A (S. cerevisiae)
chr6_-_27440837 0.23 ENST00000211936.6
ZNF184
zinc finger protein 184
chr1_+_100817262 0.23 ENST00000455467.1
CDC14A
cell division cycle 14A
chr2_+_27071292 0.23 ENST00000431402.1
ENST00000434719.1
DPYSL5
dihydropyrimidinase-like 5
chr19_+_8274185 0.22 ENST00000558268.1
ENST00000558331.1
CERS4
ceramide synthase 4
chr11_-_117747434 0.22 ENST00000529335.2
ENST00000530956.1
ENST00000260282.4
FXYD6
FXYD domain containing ion transport regulator 6
chr14_-_35344093 0.22 ENST00000382422.2
BAZ1A
bromodomain adjacent to zinc finger domain, 1A
chr17_+_57233087 0.22 ENST00000578777.1
ENST00000577457.1
ENST00000582995.1
PRR11
proline rich 11
chr2_+_11679963 0.22 ENST00000263834.5
GREB1
growth regulation by estrogen in breast cancer 1
chr7_-_148725544 0.21 ENST00000413966.1
PDIA4
protein disulfide isomerase family A, member 4
chr17_-_79919713 0.21 ENST00000425009.1
NOTUM
notum pectinacetylesterase homolog (Drosophila)
chr14_+_75746781 0.21 ENST00000555347.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr6_+_64281906 0.21 ENST00000370651.3
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr3_-_148804275 0.20 ENST00000392912.2
ENST00000465259.1
ENST00000310053.5
ENST00000494055.1
HLTF
helicase-like transcription factor
chr14_-_23791484 0.20 ENST00000594872.1
AL049829.1
Uncharacterized protein
chr8_+_32579321 0.20 ENST00000522402.1
NRG1
neuregulin 1
chr8_-_17104356 0.20 ENST00000361272.4
ENST00000523917.1
CNOT7
CCR4-NOT transcription complex, subunit 7
chr17_-_46035187 0.20 ENST00000300557.2
PRR15L
proline rich 15-like
chr17_+_57297807 0.19 ENST00000284116.4
ENST00000581140.1
ENST00000581276.1
GDPD1
glycerophosphodiester phosphodiesterase domain containing 1
chr4_+_113152978 0.19 ENST00000309703.6
AP1AR
adaptor-related protein complex 1 associated regulatory protein
chr17_+_62223320 0.19 ENST00000580828.1
ENST00000582965.1
SNORA76
small nucleolar RNA, H/ACA box 76
chr2_-_9143786 0.19 ENST00000462696.1
ENST00000305997.3
MBOAT2
membrane bound O-acyltransferase domain containing 2
chr14_-_24017647 0.19 ENST00000555334.1
ZFHX2
zinc finger homeobox 2
chr5_+_102201509 0.18 ENST00000348126.2
ENST00000379787.4
PAM
peptidylglycine alpha-amidating monooxygenase
chr7_+_73868439 0.18 ENST00000424337.2
GTF2IRD1
GTF2I repeat domain containing 1
chr2_-_165697717 0.18 ENST00000439313.1
COBLL1
cordon-bleu WH2 repeat protein-like 1
chr6_-_11779403 0.17 ENST00000414691.3
ADTRP
androgen-dependent TFPI-regulating protein
chr2_+_9983483 0.17 ENST00000263663.5
TAF1B
TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
chr1_+_144339738 0.17 ENST00000538264.1
AL592284.1
Protein LOC642441
chrX_+_135229559 0.17 ENST00000394155.2
FHL1
four and a half LIM domains 1
chr9_-_34381536 0.17 ENST00000379126.3
ENST00000379127.1
ENST00000379133.3
C9orf24
chromosome 9 open reading frame 24
chr17_+_57642886 0.17 ENST00000251241.4
ENST00000451169.2
ENST00000425628.3
ENST00000584385.1
ENST00000580030.1
DHX40
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr1_+_82266053 0.16 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
LPHN2
latrophilin 2
chr14_+_74486043 0.16 ENST00000464394.1
ENST00000394009.3
CCDC176
coiled-coil domain containing 176
chr16_+_19222479 0.16 ENST00000568433.1
SYT17
synaptotagmin XVII
chr20_+_57875457 0.16 ENST00000337938.2
ENST00000311585.7
ENST00000371028.2
EDN3
endothelin 3
chr12_+_56325231 0.16 ENST00000549368.1
DGKA
diacylglycerol kinase, alpha 80kDa
chrX_+_135229600 0.15 ENST00000370690.3
FHL1
four and a half LIM domains 1
chr1_+_16085244 0.15 ENST00000400773.1
FBLIM1
filamin binding LIM protein 1
chr5_+_66124590 0.15 ENST00000490016.2
ENST00000403666.1
ENST00000450827.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr8_-_17104099 0.15 ENST00000524358.1
CNOT7
CCR4-NOT transcription complex, subunit 7
chr15_+_50474385 0.15 ENST00000267842.5
SLC27A2
solute carrier family 27 (fatty acid transporter), member 2
chr4_-_103266355 0.15 ENST00000424970.2
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr15_+_43985084 0.15 ENST00000434505.1
ENST00000411750.1
CKMT1A
creatine kinase, mitochondrial 1A
chr1_+_8378140 0.15 ENST00000377479.2
SLC45A1
solute carrier family 45, member 1
chr6_+_12008986 0.15 ENST00000491710.1
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr10_-_14613968 0.14 ENST00000488576.1
ENST00000472095.1
FAM107B
family with sequence similarity 107, member B
chr10_-_14614311 0.14 ENST00000479731.1
ENST00000468492.1
FAM107B
family with sequence similarity 107, member B
chr17_-_39093672 0.13 ENST00000209718.3
ENST00000436344.3
ENST00000485751.1
KRT23
keratin 23 (histone deacetylase inducible)
chr15_+_43885799 0.13 ENST00000449946.1
ENST00000417289.1
CKMT1B
creatine kinase, mitochondrial 1B
chr9_-_34381511 0.13 ENST00000379124.1
C9orf24
chromosome 9 open reading frame 24
chr1_+_166808692 0.13 ENST00000367876.4
POGK
pogo transposable element with KRAB domain
chr11_-_77184739 0.13 ENST00000524847.1
PAK1
p21 protein (Cdc42/Rac)-activated kinase 1
chr19_-_59030921 0.13 ENST00000354590.3
ENST00000596739.1
ZBTB45
zinc finger and BTB domain containing 45
chrX_-_117119243 0.13 ENST00000539496.1
ENST00000469946.1
KLHL13
kelch-like family member 13
chr2_+_69240302 0.13 ENST00000303714.4
ANTXR1
anthrax toxin receptor 1
chr1_+_68150744 0.13 ENST00000370986.4
ENST00000370985.3
GADD45A
growth arrest and DNA-damage-inducible, alpha
chr21_-_46330545 0.13 ENST00000320216.6
ENST00000397852.1
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr1_-_1334685 0.13 ENST00000400809.3
ENST00000408918.4
CCNL2
cyclin L2
chr8_+_29953163 0.13 ENST00000518192.1
LEPROTL1
leptin receptor overlapping transcript-like 1
chr10_+_7745232 0.12 ENST00000358415.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr4_-_5894777 0.12 ENST00000324989.7
CRMP1
collapsin response mediator protein 1
chr17_-_39526052 0.12 ENST00000251646.3
KRT33B
keratin 33B
chr2_+_234621551 0.12 ENST00000608381.1
ENST00000373414.3
UGT1A1
UGT1A5
UDP glucuronosyltransferase 1 family, polypeptide A8
UDP glucuronosyltransferase 1 family, polypeptide A5
chr19_+_1452188 0.12 ENST00000587149.1
APC2
adenomatosis polyposis coli 2
chr15_-_64995399 0.11 ENST00000559753.1
ENST00000560258.2
ENST00000559912.2
ENST00000326005.6
OAZ2
ornithine decarboxylase antizyme 2
chr14_-_21502944 0.11 ENST00000382951.3
RNASE13
ribonuclease, RNase A family, 13 (non-active)
chr1_-_54304212 0.11 ENST00000540001.1
NDC1
NDC1 transmembrane nucleoporin
chr21_+_18811205 0.11 ENST00000440664.1
C21orf37
chromosome 21 open reading frame 37
chr4_+_79567314 0.11 ENST00000503539.1
ENST00000504675.1
RP11-792D21.2
long intergenic non-protein coding RNA 1094
chr8_+_29952914 0.11 ENST00000321250.8
ENST00000518001.1
ENST00000520682.1
ENST00000442880.2
ENST00000523116.1
LEPROTL1
leptin receptor overlapping transcript-like 1
chr8_+_32579341 0.11 ENST00000519240.1
ENST00000539990.1
NRG1
neuregulin 1
chr1_-_200992827 0.10 ENST00000332129.2
ENST00000422435.2
KIF21B
kinesin family member 21B
chr1_+_43424698 0.10 ENST00000431759.1
SLC2A1-AS1
SLC2A1 antisense RNA 1
chr1_-_65533390 0.10 ENST00000448344.1
RP4-535B20.1
RP4-535B20.1
chr15_-_65670360 0.10 ENST00000327987.4
IGDCC3
immunoglobulin superfamily, DCC subclass, member 3
chr1_+_200993071 0.10 ENST00000446333.1
ENST00000458003.1
RP11-168O16.1
RP11-168O16.1
chr14_+_57857262 0.10 ENST00000555166.1
ENST00000556492.1
ENST00000554703.1
NAA30
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr13_+_76334795 0.10 ENST00000526202.1
ENST00000465261.2
LMO7
LIM domain 7
chr8_+_21777243 0.10 ENST00000521303.1
XPO7
exportin 7
chr19_-_7990991 0.09 ENST00000318978.4
CTXN1
cortexin 1
chr9_+_139221880 0.09 ENST00000392945.3
ENST00000440944.1
GPSM1
G-protein signaling modulator 1
chr11_-_87908600 0.09 ENST00000531138.1
ENST00000526372.1
ENST00000243662.6
RAB38
RAB38, member RAS oncogene family
chr3_+_189349162 0.09 ENST00000264731.3
ENST00000382063.4
ENST00000418709.2
ENST00000320472.5
ENST00000392460.3
ENST00000440651.2
TP63
tumor protein p63
chr6_+_119215308 0.09 ENST00000229595.5
ASF1A
anti-silencing function 1A histone chaperone
chr11_-_62474803 0.09 ENST00000533982.1
ENST00000360796.5
BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr6_-_107436473 0.09 ENST00000369042.1
BEND3
BEN domain containing 3
chr2_+_47168630 0.09 ENST00000263737.6
TTC7A
tetratricopeptide repeat domain 7A
chr1_-_54303934 0.09 ENST00000537333.1
NDC1
NDC1 transmembrane nucleoporin
chr7_-_148725733 0.09 ENST00000286091.4
PDIA4
protein disulfide isomerase family A, member 4
chr2_+_69240511 0.09 ENST00000409349.3
ANTXR1
anthrax toxin receptor 1
chrX_-_100183894 0.09 ENST00000328526.5
ENST00000372956.2
XKRX
XK, Kell blood group complex subunit-related, X-linked
chr15_+_43985725 0.09 ENST00000413453.2
CKMT1A
creatine kinase, mitochondrial 1A
chr9_-_74525847 0.09 ENST00000377041.2
ABHD17B
abhydrolase domain containing 17B
chr5_-_67730240 0.09 ENST00000507733.1
CTC-537E7.3
CTC-537E7.3
chr1_+_78383813 0.08 ENST00000342754.5
NEXN
nexilin (F actin binding protein)
chr1_+_47799542 0.08 ENST00000471289.2
ENST00000450808.2
CMPK1
cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chr12_-_31477072 0.08 ENST00000454658.2
FAM60A
family with sequence similarity 60, member A
chr19_+_8274204 0.08 ENST00000561053.1
ENST00000251363.5
ENST00000559450.1
ENST00000559336.1
CERS4
ceramide synthase 4
chr3_+_179280668 0.08 ENST00000429709.2
ENST00000450518.2
ENST00000392662.1
ENST00000490364.1
ACTL6A
actin-like 6A
chr4_-_69215467 0.08 ENST00000579690.1
YTHDC1
YTH domain containing 1
chr2_+_47168313 0.08 ENST00000319190.5
ENST00000394850.2
ENST00000536057.1
TTC7A
tetratricopeptide repeat domain 7A
chr19_+_51152702 0.08 ENST00000425202.1
C19orf81
chromosome 19 open reading frame 81
chr11_-_76155618 0.08 ENST00000530759.1
RP11-111M22.3
RP11-111M22.3
chr17_+_72428266 0.08 ENST00000582473.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr10_-_25241499 0.08 ENST00000376378.1
ENST00000376376.3
ENST00000320152.6
PRTFDC1
phosphoribosyl transferase domain containing 1
chr1_+_61330931 0.08 ENST00000371191.1
NFIA
nuclear factor I/A
chr2_+_169923577 0.08 ENST00000432060.2
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr1_+_93913713 0.08 ENST00000604705.1
ENST00000370253.2
FNBP1L
formin binding protein 1-like
chr9_-_74979420 0.08 ENST00000343431.2
ENST00000376956.3
ZFAND5
zinc finger, AN1-type domain 5
chr14_+_39644387 0.08 ENST00000553331.1
ENST00000216832.4
PNN
pinin, desmosome associated protein
chr12_+_15475462 0.08 ENST00000543886.1
ENST00000348962.2
PTPRO
protein tyrosine phosphatase, receptor type, O
chr6_-_11779174 0.07 ENST00000379413.2
ADTRP
androgen-dependent TFPI-regulating protein
chr15_+_90744745 0.07 ENST00000558051.1
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr3_-_134093395 0.07 ENST00000249883.5
AMOTL2
angiomotin like 2
chr4_-_120243545 0.07 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr19_-_49864746 0.07 ENST00000598810.1
TEAD2
TEA domain family member 2
chr17_+_42081914 0.07 ENST00000293404.3
ENST00000589767.1
NAGS
N-acetylglutamate synthase
chr13_+_76334567 0.07 ENST00000321797.8
LMO7
LIM domain 7
chr13_+_39612442 0.07 ENST00000470258.1
ENST00000379600.3
NHLRC3
NHL repeat containing 3
chr1_-_38061522 0.07 ENST00000373062.3
GNL2
guanine nucleotide binding protein-like 2 (nucleolar)
chr12_+_56324756 0.07 ENST00000331886.5
ENST00000555090.1
DGKA
diacylglycerol kinase, alpha 80kDa
chr14_+_101293687 0.07 ENST00000455286.1
MEG3
maternally expressed 3 (non-protein coding)
chr13_+_76210448 0.06 ENST00000377499.5
LMO7
LIM domain 7
chr6_-_151712673 0.06 ENST00000325144.4
ZBTB2
zinc finger and BTB domain containing 2
chr2_+_33172221 0.06 ENST00000354476.3
LTBP1
latent transforming growth factor beta binding protein 1
chr13_+_98086445 0.06 ENST00000245304.4
RAP2A
RAP2A, member of RAS oncogene family
chr2_-_39348137 0.06 ENST00000426016.1
SOS1
son of sevenless homolog 1 (Drosophila)
chr4_-_157892498 0.06 ENST00000502773.1
PDGFC
platelet derived growth factor C
chr15_-_79103757 0.06 ENST00000388820.4
ADAMTS7
ADAM metallopeptidase with thrombospondin type 1 motif, 7
chr18_+_3450161 0.06 ENST00000551402.1
ENST00000577543.1
TGIF1
TGFB-induced factor homeobox 1
chr18_-_24445664 0.06 ENST00000578776.1
AQP4
aquaporin 4
chr19_+_11071652 0.06 ENST00000344626.4
ENST00000429416.3
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr9_-_88896977 0.06 ENST00000311534.6
ISCA1
iron-sulfur cluster assembly 1
chrX_-_132091284 0.06 ENST00000370833.2
HS6ST2
heparan sulfate 6-O-sulfotransferase 2
chr6_-_33547975 0.06 ENST00000442998.2
ENST00000360661.5
BAK1
BCL2-antagonist/killer 1
chr12_+_56324933 0.06 ENST00000549629.1
ENST00000555218.1
DGKA
diacylglycerol kinase, alpha 80kDa
chr20_+_45947246 0.06 ENST00000599904.1
AL031666.2
HCG2018772; Uncharacterized protein; cDNA FLJ31609 fis, clone NT2RI2002852
chr1_-_225840747 0.05 ENST00000366843.2
ENST00000366844.3
ENAH
enabled homolog (Drosophila)
chr7_-_105926058 0.05 ENST00000417537.1
NAMPT
nicotinamide phosphoribosyltransferase
chr20_+_57875758 0.05 ENST00000395654.3
EDN3
endothelin 3
chr1_+_151171012 0.05 ENST00000349792.5
ENST00000409426.1
ENST00000441902.2
ENST00000368890.4
ENST00000424999.1
ENST00000368888.4
PIP5K1A
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
chr19_-_11450249 0.05 ENST00000222120.3
RAB3D
RAB3D, member RAS oncogene family
chr10_+_112631547 0.05 ENST00000280154.7
ENST00000393104.2
PDCD4
programmed cell death 4 (neoplastic transformation inhibitor)
chr15_-_52263937 0.05 ENST00000315141.5
ENST00000299601.5
LEO1
Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr21_-_34144157 0.05 ENST00000331923.4
PAXBP1
PAX3 and PAX7 binding protein 1
chrX_+_54835493 0.05 ENST00000396224.1
MAGED2
melanoma antigen family D, 2
chr17_-_61819229 0.05 ENST00000447001.3
ENST00000392950.4
STRADA
STE20-related kinase adaptor alpha
chr8_-_29939933 0.05 ENST00000522794.1
TMEM66
transmembrane protein 66
chr13_-_39612176 0.05 ENST00000352251.3
ENST00000350125.3
PROSER1
proline and serine rich 1
chr6_-_33548006 0.05 ENST00000374467.3
BAK1
BCL2-antagonist/killer 1
chr6_-_32145861 0.05 ENST00000336984.6
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr7_+_110731062 0.05 ENST00000308478.5
ENST00000451085.1
ENST00000422987.3
ENST00000421101.1
LRRN3
leucine rich repeat neuronal 3
chr4_-_69215699 0.05 ENST00000510746.1
ENST00000344157.4
ENST00000355665.3
YTHDC1
YTH domain containing 1
chr2_+_169923504 0.04 ENST00000357546.2
DHRS9
dehydrogenase/reductase (SDR family) member 9
chr10_-_14614122 0.04 ENST00000378465.3
ENST00000452706.2
ENST00000378458.2
FAM107B
family with sequence similarity 107, member B
chr2_+_9983642 0.04 ENST00000396242.3
TAF1B
TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
chr12_+_54402790 0.04 ENST00000040584.4
HOXC8
homeobox C8
chr1_-_54303949 0.04 ENST00000234725.8
NDC1
NDC1 transmembrane nucleoporin
chr14_-_74485960 0.04 ENST00000556242.1
ENST00000334696.6
ENTPD5
ectonucleoside triphosphate diphosphohydrolase 5
chr19_+_11071546 0.04 ENST00000358026.2
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
chr2_-_241835561 0.04 ENST00000388934.4
C2orf54
chromosome 2 open reading frame 54
chr18_+_3449821 0.04 ENST00000407501.2
ENST00000405385.3
ENST00000546979.1
TGIF1
TGFB-induced factor homeobox 1
chr5_-_58335281 0.04 ENST00000358923.6
PDE4D
phosphodiesterase 4D, cAMP-specific
chr1_+_110091189 0.04 ENST00000369851.4
GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr1_-_6479963 0.04 ENST00000377836.4
ENST00000487437.1
ENST00000489730.1
ENST00000377834.4
HES2
hes family bHLH transcription factor 2

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF7L1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.2 0.5 GO:0045360 interleukin-1 biosynthetic process(GO:0042222) regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.1 0.3 GO:0100012 negative regulation of mesodermal cell fate specification(GO:0042662) regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012)
0.1 0.2 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.1 0.2 GO:0051300 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.1 0.5 GO:0018032 protein amidation(GO:0018032)
0.1 0.7 GO:0021840 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 0.2 GO:1990697 protein depalmitoleylation(GO:1990697)
0.1 0.2 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.1 0.2 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.0 0.2 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 0.1 GO:1904530 negative regulation of actin filament binding(GO:1904530) negative regulation of actin binding(GO:1904617)
0.0 0.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.2 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.4 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0 0.1 GO:0002352 B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0 0.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.4 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.2 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.0 0.2 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.6 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.0 0.1 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.1 GO:0070980 biphenyl catabolic process(GO:0070980)
0.0 0.1 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.2 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.3 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:0007068 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.0 0.3 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.3 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.1 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.0 0.3 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.4 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.1 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 0.1 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.1 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.2 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.1 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0075341 host cell PML body(GO:0075341)
0.1 0.2 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.1 0.2 GO:0008623 CHRAC(GO:0008623)
0.1 0.2 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.1 1.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.3 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.5 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 0.6 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.5 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.1 0.3 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 0.2 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.1 1.8 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.7 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.3 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.3 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.1 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.0 0.1 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.3 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.2 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 0.1 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.3 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.6 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.4 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol