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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TCF21

Z-value: 0.97

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Transcription factors associated with TCF21

Gene Symbol Gene ID Gene Info
ENSG00000118526.6 transcription factor 21

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TCF21hg19_v2_chr6_+_134210243_1342102760.286.0e-01Click!

Activity profile of TCF21 motif

Sorted Z-values of TCF21 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_615570 2.09 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
interferon regulatory factor 7
chr1_+_79115503 1.51 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
interferon-induced protein 44
chr11_-_615942 1.23 ENST00000397562.3
ENST00000330243.5
ENST00000397570.1
ENST00000397574.2
interferon regulatory factor 7
chr11_+_117103333 0.83 ENST00000534428.1
ring finger protein 214
chr2_+_231280954 0.79 ENST00000409824.1
ENST00000409341.1
ENST00000409112.1
ENST00000340126.4
ENST00000341950.4
SP100 nuclear antigen
chr2_+_231280908 0.71 ENST00000427101.2
ENST00000432979.1
SP100 nuclear antigen
chr1_+_92414952 0.56 ENST00000449584.1
ENST00000427104.1
ENST00000355011.3
ENST00000448194.1
ENST00000426141.1
ENST00000450792.1
ENST00000548992.1
ENST00000552654.1
ENST00000457265.1
bromodomain, testis-specific
chr3_+_167453493 0.53 ENST00000295777.5
ENST00000472747.2
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr6_-_41673552 0.48 ENST00000419574.1
ENST00000445214.1
transcription factor EB
chr2_-_7005785 0.46 ENST00000256722.5
ENST00000404168.1
ENST00000458098.1
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr13_+_41635617 0.42 ENST00000542082.1
WW domain binding protein 4
chr1_+_172422026 0.41 ENST00000367725.4
chromosome 1 open reading frame 105
chr17_+_71228793 0.40 ENST00000426147.2
chromosome 17 open reading frame 80
chr17_+_71229346 0.40 ENST00000535032.2
ENST00000582793.1
chromosome 17 open reading frame 80
chr8_-_99837856 0.40 ENST00000518165.1
ENST00000419617.2
serine/threonine kinase 3
chr17_-_62499334 0.39 ENST00000579996.1
DEAD (Asp-Glu-Ala-Asp) box helicase 5
chr11_+_117103441 0.37 ENST00000531287.1
ENST00000531452.1
ring finger protein 214
chr10_+_52499682 0.37 ENST00000185907.9
ENST00000374006.1
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2B
chr22_-_22863466 0.37 ENST00000406426.1
ENST00000360412.2
zinc finger protein 280B
chr20_-_23402028 0.37 ENST00000398425.3
ENST00000432543.2
ENST00000377026.4
N-ethylmaleimide-sensitive factor attachment protein, beta
chrM_+_7586 0.37 ENST00000361739.1
mitochondrially encoded cytochrome c oxidase II
chr2_+_149402009 0.37 ENST00000457184.1
enhancer of polycomb homolog 2 (Drosophila)
chr2_+_86116396 0.36 ENST00000455121.3
AC105053.4
chr8_-_71519889 0.36 ENST00000521425.1
translocation associated membrane protein 1
chr19_-_33716750 0.34 ENST00000253188.4
solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10
chr2_+_44001172 0.34 ENST00000260605.8
ENST00000406852.3
ENST00000443170.3
ENST00000398823.2
ENST00000605786.1
dynein, cytoplasmic 2, light intermediate chain 1
chr12_-_50677255 0.33 ENST00000551691.1
ENST00000394943.3
ENST00000341247.4
LIM domain and actin binding 1
chr13_-_20767037 0.33 ENST00000382848.4
gap junction protein, beta 2, 26kDa
chr10_-_105238997 0.32 ENST00000369783.4
calcium homeostasis modulator 3
chr2_-_17981462 0.31 ENST00000402989.1
ENST00000428868.1
structural maintenance of chromosomes 6
chr3_-_81792780 0.31 ENST00000489715.1
glucan (1,4-alpha-), branching enzyme 1
chr11_+_74862100 0.31 ENST00000532236.1
ENST00000531756.1
solute carrier organic anion transporter family, member 2B1
chr2_+_38177575 0.31 ENST00000407257.1
ENST00000417700.2
ENST00000234195.3
ENST00000442857.1
regulator of microtubule dynamics 2
chr9_-_123812542 0.31 ENST00000223642.1
complement component 5
chr17_+_68165657 0.31 ENST00000243457.3
potassium inwardly-rectifying channel, subfamily J, member 2
chr11_-_10920714 0.30 ENST00000533941.1
CTD-2003C8.2
chr17_-_7193711 0.30 ENST00000571464.1
Y box binding protein 2
chr3_+_167453026 0.29 ENST00000472941.1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr17_+_11924129 0.29 ENST00000353533.5
ENST00000415385.3
mitogen-activated protein kinase kinase 4
chr17_+_71228740 0.29 ENST00000268942.8
ENST00000359042.2
chromosome 17 open reading frame 80
chr20_-_52790055 0.29 ENST00000395955.3
cytochrome P450, family 24, subfamily A, polypeptide 1
chr15_+_65337708 0.29 ENST00000334287.2
solute carrier family 51, beta subunit
chr21_+_37692481 0.27 ENST00000400485.1
MORC family CW-type zinc finger 3
chr11_-_10920838 0.27 ENST00000503469.2
CTD-2003C8.2
chrX_+_17755696 0.27 ENST00000419185.1
sex comb on midleg-like 1 (Drosophila)
chr5_+_170288856 0.26 ENST00000523189.1
RAN binding protein 17
chr17_+_34848049 0.26 ENST00000588902.1
ENST00000591067.1
zinc finger, HIT-type containing 3
chr1_-_63782888 0.26 ENST00000436475.2
long intergenic non-protein coding RNA 466
chr19_+_1452188 0.25 ENST00000587149.1
adenomatosis polyposis coli 2
chr18_+_3247779 0.25 ENST00000578611.1
ENST00000583449.1
myosin, light chain 12A, regulatory, non-sarcomeric
chr9_-_3469181 0.25 ENST00000366116.2
Uncharacterized protein
chr5_-_102455801 0.24 ENST00000508629.1
ENST00000399004.2
gypsy retrotransposon integrase 1
chr1_-_150669604 0.24 ENST00000427665.1
ENST00000540514.1
golgi phosphoprotein 3-like
chr18_+_158513 0.24 ENST00000400266.3
ENST00000580410.1
ENST00000383589.2
ENST00000261601.7
ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
chr11_+_74862032 0.24 ENST00000289575.5
ENST00000341411.4
solute carrier organic anion transporter family, member 2B1
chr15_+_63796779 0.23 ENST00000561442.1
ENST00000560070.1
ENST00000540797.1
ENST00000380324.3
ENST00000268049.7
ENST00000536001.1
ENST00000539772.1
ubiquitin specific peptidase 3
chr12_+_104458235 0.23 ENST00000229330.4
host cell factor C2
chr2_-_122494487 0.23 ENST00000451734.1
ENST00000285814.4
nucleolar protein interacting with the FHA domain of MKI67
chr10_+_94594351 0.23 ENST00000371552.4
exocyst complex component 6
chr8_+_33342268 0.22 ENST00000360128.6
MAK16 homolog (S. cerevisiae)
chr9_+_6758109 0.22 ENST00000536108.1
lysine (K)-specific demethylase 4C
chr17_+_38083977 0.22 ENST00000578802.1
ENST00000578478.1
ENST00000582263.1
RP11-387H17.4
chr6_-_30080876 0.21 ENST00000376734.3
tripartite motif containing 31
chr21_+_30673091 0.21 ENST00000447177.1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr11_+_74862140 0.21 ENST00000525650.1
ENST00000454962.2
solute carrier organic anion transporter family, member 2B1
chr3_+_169684553 0.21 ENST00000337002.4
ENST00000480708.1
SEC62 homolog (S. cerevisiae)
chr17_-_191188 0.21 ENST00000575634.1
rabphilin 3A-like (without C2 domains)
chr10_-_7661623 0.20 ENST00000298441.6
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr2_+_171627597 0.20 ENST00000429172.1
ENST00000426475.1
AC007405.6
chr12_+_56473628 0.20 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr14_-_53258180 0.20 ENST00000554230.1
glucosamine-phosphate N-acetyltransferase 1
chr13_-_50510434 0.19 ENST00000361840.3
SPRY domain containing 7
chr13_-_50510622 0.19 ENST00000378195.2
SPRY domain containing 7
chr3_+_122296465 0.19 ENST00000483793.1
poly (ADP-ribose) polymerase family, member 15
chr8_-_82633476 0.19 ENST00000518419.1
ENST00000517588.1
ENST00000521895.1
ENST00000520076.1
ENST00000519523.1
ENST00000522520.1
ENST00000521287.1
ENST00000523096.1
ENST00000220669.5
ENST00000517450.1
zinc finger, AN1-type domain 1
chr1_-_114429997 0.19 ENST00000471267.1
ENST00000393320.3
BCL2-like 15
chr3_-_176915215 0.19 ENST00000457928.2
ENST00000422442.1
transducin (beta)-like 1 X-linked receptor 1
chr11_-_14913765 0.19 ENST00000334636.5
cytochrome P450, family 2, subfamily R, polypeptide 1
chr14_-_23288930 0.19 ENST00000554517.1
ENST00000285850.7
ENST00000397529.2
ENST00000555702.1
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr17_+_39421591 0.19 ENST00000391355.1
keratin associated protein 9-6
chr9_+_6758024 0.19 ENST00000442236.2
lysine (K)-specific demethylase 4C
chr14_-_50154921 0.19 ENST00000553805.2
ENST00000554396.1
ENST00000216367.5
ENST00000539565.2
polymerase (DNA directed), epsilon 2, accessory subunit
chr1_+_78354297 0.18 ENST00000334785.7
nexilin (F actin binding protein)
chr3_+_179065474 0.18 ENST00000471841.1
ENST00000280653.7
mitofusin 1
chr8_-_19540266 0.18 ENST00000311540.4
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr8_-_55014415 0.18 ENST00000522007.1
ENST00000521898.1
ENST00000518546.1
ENST00000316963.3
lysophospholipase I
chr1_-_150849208 0.18 ENST00000358595.5
aryl hydrocarbon receptor nuclear translocator
chr17_-_39183452 0.18 ENST00000361883.5
keratin associated protein 1-5
chr20_-_1165319 0.18 ENST00000429036.1
transmembrane protein 74B
chr2_+_113321939 0.18 ENST00000458012.2
polymerase (RNA) I polypeptide B, 128kDa
chr3_+_183948161 0.18 ENST00000426955.2
von Willebrand factor A domain containing 5B2
chr15_+_57998821 0.18 ENST00000299638.3
polymerase (RNA) II (DNA directed) polypeptide M
chr15_-_99548775 0.18 ENST00000378919.6
pyroglutamyl-peptidase I-like
chr12_+_72233487 0.18 ENST00000482439.2
ENST00000550746.1
ENST00000491063.1
ENST00000319106.8
ENST00000485960.2
ENST00000393309.3
TBC1 domain family, member 15
chr6_+_31554962 0.18 ENST00000376092.3
ENST00000376086.3
ENST00000303757.8
ENST00000376093.2
ENST00000376102.3
leukocyte specific transcript 1
chr6_+_44355257 0.17 ENST00000371477.3
cell division cycle 5-like
chrX_-_108868390 0.17 ENST00000372101.2
KCNE1-like
chr8_-_19540086 0.17 ENST00000332246.6
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr2_+_33701707 0.17 ENST00000425210.1
ENST00000444784.1
ENST00000423159.1
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr1_-_6550625 0.17 ENST00000377725.1
ENST00000340850.5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr2_+_192110199 0.17 ENST00000304164.4
myosin IB
chr5_+_68513557 0.17 ENST00000256441.4
mitochondrial ribosomal protein S36
chr11_-_64512469 0.17 ENST00000377485.1
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr15_+_57998923 0.17 ENST00000380557.4
polymerase (RNA) II (DNA directed) polypeptide M
chr10_-_51130715 0.17 ENST00000402038.3
poly (ADP-ribose) glycohydrolase
chr5_-_58571935 0.16 ENST00000503258.1
phosphodiesterase 4D, cAMP-specific
chr3_-_182833863 0.16 ENST00000492597.1
methylcrotonoyl-CoA carboxylase 1 (alpha)
chr15_+_89787180 0.16 ENST00000300027.8
ENST00000310775.7
ENST00000567891.1
ENST00000564920.1
ENST00000565255.1
ENST00000567996.1
ENST00000451393.2
ENST00000563250.1
Fanconi anemia, complementation group I
chr16_+_55522536 0.16 ENST00000570283.1
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr12_-_52845910 0.16 ENST00000252252.3
keratin 6B
chr12_-_68845417 0.16 ENST00000542875.1
RP11-81H14.2
chr17_+_4487294 0.16 ENST00000338859.4
smoothelin-like 2
chr14_+_31091511 0.16 ENST00000544052.2
ENST00000421551.3
ENST00000541123.1
ENST00000557076.1
ENST00000553693.1
ENST00000396629.2
sec1 family domain containing 1
chr4_+_95972822 0.16 ENST00000509540.1
ENST00000440890.2
bone morphogenetic protein receptor, type IB
chr12_+_50355647 0.16 ENST00000293599.6
aquaporin 5
chr9_-_100954910 0.16 ENST00000375077.4
coronin, actin binding protein, 2A
chr12_+_16500599 0.16 ENST00000535309.1
ENST00000540056.1
ENST00000396209.1
ENST00000540126.1
microsomal glutathione S-transferase 1
chr16_-_9030515 0.15 ENST00000535863.1
ENST00000381886.4
ubiquitin specific peptidase 7 (herpes virus-associated)
chr17_-_7081435 0.15 ENST00000380920.4
asialoglycoprotein receptor 1
chr1_-_39339777 0.15 ENST00000397572.2
MYC binding protein
chr2_-_158345341 0.15 ENST00000435117.1
cytohesin 1 interacting protein
chr2_+_68384976 0.15 ENST00000263657.2
partner of NOB1 homolog (S. cerevisiae)
chr6_-_13711773 0.14 ENST00000011619.3
RAN binding protein 9
chr6_+_143772060 0.14 ENST00000367591.4
peroxisomal biogenesis factor 3
chr12_+_16500571 0.14 ENST00000543076.1
ENST00000396210.3
microsomal glutathione S-transferase 1
chr6_-_27835357 0.14 ENST00000331442.3
histone cluster 1, H1b
chr5_-_142784101 0.14 ENST00000503201.1
ENST00000502892.1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr10_+_17686221 0.14 ENST00000540523.1
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr10_-_12084770 0.14 ENST00000357604.5
UPF2 regulator of nonsense transcripts homolog (yeast)
chr19_-_45826125 0.14 ENST00000221476.3
creatine kinase, muscle
chr2_-_190627481 0.14 ENST00000264151.5
ENST00000520350.1
ENST00000521630.1
ENST00000517895.1
O-sialoglycoprotein endopeptidase-like 1
chr20_-_23030296 0.14 ENST00000377103.2
thrombomodulin
chr7_+_99102573 0.14 ENST00000394170.2
zinc finger with KRAB and SCAN domains 5
chr9_-_130541017 0.14 ENST00000314830.8
SH2 domain containing 3C
chr14_+_69658194 0.14 ENST00000409018.3
ENST00000409014.1
ENST00000409675.1
exonuclease 3'-5' domain containing 2
chr8_-_30013748 0.13 ENST00000607315.1
RP11-51J9.5
chr7_+_87563557 0.13 ENST00000439864.1
ENST00000412441.1
ENST00000398201.4
ENST00000265727.7
ENST00000315984.7
ENST00000398209.3
ADAM metallopeptidase domain 22
chr5_+_49962772 0.13 ENST00000281631.5
ENST00000513738.1
ENST00000503665.1
ENST00000514067.2
ENST00000503046.1
poly (ADP-ribose) polymerase family, member 8
chr12_+_8850471 0.13 ENST00000535829.1
ENST00000357529.3
ribosomal modification protein rimK-like family member B
chr3_-_10332416 0.13 ENST00000450603.1
ENST00000449554.2
ghrelin/obestatin prepropeptide
chr4_-_89152474 0.13 ENST00000515655.1
ATP-binding cassette, sub-family G (WHITE), member 2
chr13_+_37574678 0.13 ENST00000389704.3
exosome component 8
chr6_-_31648150 0.13 ENST00000375858.3
ENST00000383237.4
lymphocyte antigen 6 complex, locus G5C
chr3_+_145782358 0.13 ENST00000422482.1
HCG1786590; PRO2533; Uncharacterized protein
chr6_+_116832789 0.13 ENST00000368599.3
family with sequence similarity 26, member E
chr2_-_224702270 0.13 ENST00000396654.2
ENST00000396653.2
ENST00000423110.1
ENST00000443700.1
adaptor-related protein complex 1, sigma 3 subunit
chr19_-_50400212 0.13 ENST00000391826.2
interleukin 4 induced 1
chr2_+_33701286 0.13 ENST00000403687.3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chrX_-_16887963 0.13 ENST00000380084.4
retinoblastoma binding protein 7
chr20_-_1165117 0.13 ENST00000381894.3
transmembrane protein 74B
chr10_-_46641003 0.13 ENST00000395721.2
ENST00000374218.2
ENST00000395725.3
ENST00000374346.3
ENST00000417004.1
protein tyrosine phosphatase, non-receptor type 20A
chr12_-_105352080 0.13 ENST00000433540.1
solute carrier family 41 (magnesium transporter), member 2
chr4_-_123843597 0.13 ENST00000510735.1
ENST00000304430.5
nudix (nucleoside diphosphate linked moiety X)-type motif 6
chr2_-_191115229 0.12 ENST00000409820.2
ENST00000410045.1
3-hydroxyisobutyryl-CoA hydrolase
chr12_+_9142131 0.12 ENST00000356986.3
ENST00000266551.4
killer cell lectin-like receptor subfamily G, member 1
chr7_+_66205712 0.12 ENST00000451741.2
ENST00000442563.1
ENST00000450873.2
ENST00000284957.5
potassium channel tetramerization domain containing 7
RAB guanine nucleotide exchange factor (GEF) 1
chr14_-_45431091 0.12 ENST00000579157.1
ENST00000396128.4
ENST00000556500.1
kelch-like family member 28
chr8_-_123706338 0.12 ENST00000521608.1
long intergenic non-protein coding RNA 1151
chr9_+_6757634 0.12 ENST00000543771.1
ENST00000401787.3
ENST00000381306.3
ENST00000381309.3
lysine (K)-specific demethylase 4C
chr1_+_25757376 0.12 ENST00000399766.3
ENST00000399763.3
ENST00000374343.4
transmembrane protein 57
chr3_-_54962100 0.12 ENST00000273286.5
leucine-rich repeats and transmembrane domains 1
chr11_-_88070920 0.12 ENST00000524463.1
ENST00000227266.5
cathepsin C
chr2_+_234602305 0.12 ENST00000406651.1
UDP glucuronosyltransferase 1 family, polypeptide A6
chr11_-_82997420 0.12 ENST00000455220.2
ENST00000529689.1
coiled-coil domain containing 90B
chr3_+_197677379 0.12 ENST00000442341.1
ribosomal protein L35a
chr12_+_14572070 0.12 ENST00000545769.1
ENST00000428217.2
ENST00000396279.2
ENST00000542514.1
ENST00000536279.1
activating transcription factor 7 interacting protein
chr16_+_5009250 0.12 ENST00000587469.1
SEC14-like 5 (S. cerevisiae)
chr14_+_58666824 0.12 ENST00000254286.4
actin-related protein 10 homolog (S. cerevisiae)
chr10_+_60094735 0.11 ENST00000373910.4
ubiquitin-conjugating enzyme E2D 1
chr16_-_832926 0.11 ENST00000293892.3
mesothelin-like
chr6_-_72130472 0.11 ENST00000426635.2
long intergenic non-protein coding RNA 472
chr4_+_186347388 0.11 ENST00000511138.1
ENST00000511581.1
chromosome 4 open reading frame 47
chr21_-_38362497 0.11 ENST00000427746.1
ENST00000336648.4
holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
chr8_+_38089198 0.11 ENST00000528358.1
ENST00000529642.1
ENST00000532222.1
ENST00000520272.2
DDHD domain containing 2
chr3_+_49059038 0.11 ENST00000451378.2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr6_+_150070857 0.11 ENST00000544496.1
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr15_+_75487984 0.11 ENST00000563905.1
chromosome 15 open reading frame 39
chr11_+_125496619 0.11 ENST00000532669.1
ENST00000278916.3
checkpoint kinase 1
chr17_+_19314505 0.11 ENST00000461366.1
ring finger protein 112
chr19_-_4559814 0.11 ENST00000586582.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
chr5_-_98262240 0.11 ENST00000284049.3
chromodomain helicase DNA binding protein 1
chr17_-_26989136 0.11 ENST00000247020.4
stromal cell-derived factor 2
chr7_+_12726623 0.10 ENST00000439721.1
ADP-ribosylation factor-like 4A
chrX_+_9880412 0.10 ENST00000418909.2
shroom family member 2
chr6_+_150070831 0.10 ENST00000367380.5
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr7_-_25164868 0.10 ENST00000409409.1
ENST00000409764.1
ENST00000413447.1
cytochrome c, somatic
chr3_+_113666748 0.10 ENST00000330212.3
ENST00000498275.1
zinc finger, DHHC-type containing 23
chr16_-_3422283 0.10 ENST00000399974.3
MT-RNR2-like 4
chr19_+_57999101 0.10 ENST00000347466.6
ENST00000523138.1
ENST00000415379.2
ENST00000521754.1
ENST00000221735.7
ENST00000518999.1
ENST00000521137.1
zinc finger protein 419
chr6_+_31555045 0.10 ENST00000396101.3
ENST00000490742.1
leukocyte specific transcript 1
chr14_+_67999999 0.10 ENST00000329153.5
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr4_-_140223670 0.10 ENST00000394228.1
ENST00000539387.1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr3_+_49058444 0.10 ENST00000326925.6
ENST00000395458.2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr7_-_48068643 0.10 ENST00000453192.2
Sad1 and UNC84 domain containing 3
chr7_-_132766800 0.10 ENST00000542753.1
ENST00000448878.1
coiled-coil-helix-coiled-coil-helix domain containing 3
chr5_+_130506629 0.10 ENST00000510516.1
ENST00000507584.1
LYR motif containing 7
chr1_-_150849174 0.10 ENST00000515192.1
aryl hydrocarbon receptor nuclear translocator
chr6_+_17102489 0.09 ENST00000536551.1
stathmin domain containing 1
chr22_-_50964558 0.09 ENST00000535425.1
ENST00000439934.1
SCO2 cytochrome c oxidase assembly protein
chr11_-_31531121 0.09 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)

Network of associatons between targets according to the STRING database.

First level regulatory network of TCF21

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.2 1.5 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.2 0.6 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.1 0.5 GO:0009138 pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.1 0.3 GO:0051685 maintenance of ER location(GO:0051685)
0.1 0.3 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.3 GO:0009386 translational attenuation(GO:0009386)
0.1 0.4 GO:0044752 response to human chorionic gonadotropin(GO:0044752)
0.1 0.3 GO:0042369 vitamin D catabolic process(GO:0042369)
0.1 0.3 GO:0036378 calcitriol biosynthetic process from calciol(GO:0036378)
0.1 0.4 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.3 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 0.3 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.1 0.3 GO:2000672 cellular response to sorbitol(GO:0072709) negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.3 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.1 GO:0008057 eye pigment granule organization(GO:0008057)
0.0 0.5 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.2 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.1 GO:1904344 positive regulation of growth rate(GO:0040010) regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768)
0.0 0.4 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.2 GO:1990637 response to prolactin(GO:1990637)
0.0 0.3 GO:0042940 D-amino acid transport(GO:0042940)
0.0 0.1 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775)
0.0 0.4 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.1 GO:0038109 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0 0.2 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0 0.1 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.0 GO:0098904 regulation of AV node cell action potential(GO:0098904)
0.0 0.2 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.2 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.1 GO:0050976 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976)
0.0 0.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.3 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.2 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.3 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.0 0.3 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.0 0.4 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0097195 pilomotor reflex(GO:0097195)
0.0 0.1 GO:0006574 valine catabolic process(GO:0006574)
0.0 0.3 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.2 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.0 0.3 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.2 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.1 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.0 0.3 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.1 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.0 GO:1900195 positive regulation of oocyte maturation(GO:1900195)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.0 0.4 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.1 GO:0009726 detection of endogenous stimulus(GO:0009726)
0.0 0.1 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.0 0.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.2 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.0 0.1 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.0 0.0 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.0 0.1 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.0 GO:0033967 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.2 GO:0060613 fat pad development(GO:0060613)
0.0 0.3 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 0.1 GO:0048749 compound eye development(GO:0048749)
0.0 0.2 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.1 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.0 0.0 GO:0070295 renal water absorption(GO:0070295)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.0 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.0 0.1 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.1 GO:0045047 protein targeting to ER(GO:0045047)
0.0 0.0 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.1 GO:0035932 mineralocorticoid secretion(GO:0035931) aldosterone secretion(GO:0035932) regulation of mineralocorticoid secretion(GO:2000855) positive regulation of mineralocorticoid secretion(GO:2000857) regulation of aldosterone secretion(GO:2000858) positive regulation of aldosterone secretion(GO:2000860)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.3 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.3 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.2 GO:0002169 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.1 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.3 GO:0097449 astrocyte projection(GO:0097449)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.0 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.0 GO:0043512 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.5 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.0 GO:0005602 complement component C1 complex(GO:0005602)
0.0 0.2 GO:0070938 contractile ring(GO:0070938)
0.0 0.3 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:0034678 smooth muscle contractile fiber(GO:0030485) integrin alpha8-beta1 complex(GO:0034678)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0070087 chromo shadow domain binding(GO:0070087)
0.1 0.5 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.3 GO:0070576 vitamin D 24-hydroxylase activity(GO:0070576)
0.1 0.4 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.2 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.1 0.3 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.1 0.3 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.1 0.4 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.1 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.1 GO:0072591 citrate-L-glutamate ligase activity(GO:0072591)
0.0 0.1 GO:0016608 growth hormone-releasing hormone activity(GO:0016608) ghrelin receptor binding(GO:0031768)
0.0 0.2 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.4 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.1 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.0 0.1 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.8 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 3.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.2 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.3 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.2 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.2 GO:0015250 water channel activity(GO:0015250)
0.0 0.3 GO:0043295 glutathione binding(GO:0043295)
0.0 0.2 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.0 GO:0036009 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.0 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.1 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.0 GO:0047860 diiodophenylpyruvate reductase activity(GO:0047860)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.0 GO:0090541 MIT domain binding(GO:0090541)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.9 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.8 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.1 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling