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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TBX4

Z-value: 1.02

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Transcription factors associated with TBX4

Gene Symbol Gene ID Gene Info
TBX4
ENSG00000121075.5 T-box transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX4hg19_v2_chr17_+_59529743_595297980.187.4e-01Click!

Activity profile of TBX4 motif

Sorted Z-values of TBX4 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_167453493 1.51 ENST00000295777.5
ENST00000472747.2
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr2_-_61697862 0.80 ENST00000398571.2
USP34
ubiquitin specific peptidase 34
chr3_+_167453026 0.74 ENST00000472941.1
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr8_-_99954788 0.70 ENST00000523601.1
STK3
serine/threonine kinase 3
chrM_+_10464 0.64 ENST00000361335.1
MT-ND4L
mitochondrially encoded NADH dehydrogenase 4L
chr5_+_74807581 0.63 ENST00000241436.4
ENST00000352007.5
POLK
polymerase (DNA directed) kappa
chr7_+_107220660 0.61 ENST00000465919.1
ENST00000445771.2
ENST00000479917.1
ENST00000421217.1
ENST00000457837.1
BCAP29
B-cell receptor-associated protein 29
chr21_+_30502806 0.55 ENST00000399928.1
ENST00000399926.1
MAP3K7CL
MAP3K7 C-terminal like
chr14_-_62217779 0.54 ENST00000554254.1
HIF1A-AS2
HIF1A antisense RNA 2
chr5_+_74807886 0.54 ENST00000514296.1
POLK
polymerase (DNA directed) kappa
chr2_-_111291587 0.47 ENST00000437167.1
RGPD6
RANBP2-like and GRIP domain containing 6
chr9_+_40028620 0.46 ENST00000426179.1
AL353791.1
AL353791.1
chrM_+_10758 0.46 ENST00000361381.2
MT-ND4
mitochondrially encoded NADH dehydrogenase 4
chr8_-_95907423 0.44 ENST00000396133.3
ENST00000308108.4
CCNE2
cyclin E2
chr7_+_107220899 0.42 ENST00000379117.2
ENST00000473124.1
BCAP29
B-cell receptor-associated protein 29
chr2_-_37458749 0.36 ENST00000234170.5
CEBPZ
CCAAT/enhancer binding protein (C/EBP), zeta
chr12_-_90024360 0.35 ENST00000393164.2
ATP2B1
ATPase, Ca++ transporting, plasma membrane 1
chr14_-_45603657 0.35 ENST00000396062.3
FKBP3
FK506 binding protein 3, 25kDa
chr2_+_61108650 0.34 ENST00000295025.8
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr14_+_53196872 0.34 ENST00000442123.2
ENST00000354586.4
STYX
serine/threonine/tyrosine interacting protein
chr5_+_56469843 0.33 ENST00000514387.2
GPBP1
GC-rich promoter binding protein 1
chrM_+_10053 0.33 ENST00000361227.2
MT-ND3
mitochondrially encoded NADH dehydrogenase 3
chr4_+_140222609 0.32 ENST00000296543.5
ENST00000398947.1
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr2_-_219925189 0.32 ENST00000295731.6
IHH
indian hedgehog
chr2_+_62933001 0.31 ENST00000263991.5
ENST00000354487.3
EHBP1
EH domain binding protein 1
chr10_-_16563870 0.31 ENST00000298943.3
C1QL3
complement component 1, q subcomponent-like 3
chr13_-_52027134 0.31 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr2_-_42160486 0.30 ENST00000427054.1
AC104654.2
AC104654.2
chr5_-_78809950 0.30 ENST00000334082.6
HOMER1
homer homolog 1 (Drosophila)
chrX_+_123095546 0.30 ENST00000371157.3
ENST00000371145.3
ENST00000371144.3
STAG2
stromal antigen 2
chr1_+_16062820 0.30 ENST00000294454.5
SLC25A34
solute carrier family 25, member 34
chr11_-_85430204 0.29 ENST00000389958.3
ENST00000527794.1
SYTL2
synaptotagmin-like 2
chr7_-_105319536 0.29 ENST00000477775.1
ATXN7L1
ataxin 7-like 1
chr21_+_30503282 0.29 ENST00000399925.1
MAP3K7CL
MAP3K7 C-terminal like
chr11_+_111749650 0.28 ENST00000528125.1
C11orf1
chromosome 11 open reading frame 1
chr5_-_60240858 0.28 ENST00000426742.2
ENST00000265038.5
ENST00000543101.1
ENST00000439176.1
ERCC8
excision repair cross-complementing rodent repair deficiency, complementation group 8
chr14_+_75745477 0.28 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr3_+_142315294 0.28 ENST00000464320.1
PLS1
plastin 1
chr3_+_142315225 0.27 ENST00000457734.2
ENST00000483373.1
ENST00000475296.1
ENST00000495744.1
ENST00000476044.1
ENST00000461644.1
PLS1
plastin 1
chrX_+_16804544 0.27 ENST00000380122.5
ENST00000398155.4
TXLNG
taxilin gamma
chr11_+_114271251 0.27 ENST00000375490.5
RBM7
RNA binding motif protein 7
chr11_-_85779971 0.27 ENST00000393346.3
PICALM
phosphatidylinositol binding clathrin assembly protein
chr15_+_90319557 0.27 ENST00000341735.3
MESP2
mesoderm posterior 2 homolog (mouse)
chr2_+_62932779 0.27 ENST00000427809.1
ENST00000405482.1
ENST00000431489.1
EHBP1
EH domain binding protein 1
chrX_+_123095860 0.27 ENST00000428941.1
STAG2
stromal antigen 2
chrX_-_133930285 0.26 ENST00000486347.1
ENST00000343004.5
FAM122B
family with sequence similarity 122B
chr11_-_85430163 0.26 ENST00000529581.1
ENST00000533577.1
SYTL2
synaptotagmin-like 2
chrX_+_123095890 0.25 ENST00000435215.1
STAG2
stromal antigen 2
chr14_+_90864504 0.25 ENST00000544280.2
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr11_+_111750206 0.25 ENST00000530214.1
ENST00000530799.1
C11orf1
chromosome 11 open reading frame 1
chr5_-_74807418 0.25 ENST00000405807.4
ENST00000261415.7
COL4A3BP
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr2_+_154728426 0.24 ENST00000392825.3
ENST00000434213.1
GALNT13
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)
chr11_-_85430088 0.24 ENST00000533057.1
ENST00000533892.1
SYTL2
synaptotagmin-like 2
chr5_+_56469939 0.23 ENST00000506184.2
GPBP1
GC-rich promoter binding protein 1
chr6_-_19804973 0.23 ENST00000457670.1
ENST00000607810.1
ENST00000606628.1
RP4-625H18.2
RP4-625H18.2
chr2_+_29033682 0.23 ENST00000379579.4
ENST00000334056.5
ENST00000449210.1
SPDYA
speedy/RINGO cell cycle regulator family member A
chr1_+_35734616 0.23 ENST00000441447.1
ZMYM4
zinc finger, MYM-type 4
chr8_+_103563792 0.23 ENST00000285402.3
ODF1
outer dense fiber of sperm tails 1
chr2_+_61108771 0.23 ENST00000394479.3
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr5_+_68788594 0.23 ENST00000396442.2
ENST00000380766.2
OCLN
occludin
chr14_+_85994943 0.23 ENST00000553678.1
RP11-497E19.2
Uncharacterized protein
chr9_-_75567962 0.23 ENST00000297785.3
ENST00000376939.1
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr18_-_59561417 0.22 ENST00000591306.1
RNF152
ring finger protein 152
chrX_+_69642881 0.22 ENST00000453994.2
ENST00000536730.1
ENST00000538649.1
ENST00000374382.3
GDPD2
glycerophosphodiester phosphodiesterase domain containing 2
chr7_-_28220354 0.22 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr5_+_82767487 0.21 ENST00000343200.5
ENST00000342785.4
VCAN
versican
chr5_+_56469775 0.20 ENST00000424459.3
GPBP1
GC-rich promoter binding protein 1
chr4_-_146859787 0.19 ENST00000508784.1
ZNF827
zinc finger protein 827
chr11_+_4116054 0.19 ENST00000423050.2
RRM1
ribonucleotide reductase M1
chr2_-_85895295 0.18 ENST00000428225.1
ENST00000519937.2
SFTPB
surfactant protein B
chrX_+_46772065 0.18 ENST00000455411.1
PHF16
jade family PHD finger 3
chr12_+_104324112 0.18 ENST00000299767.5
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr1_-_1009683 0.18 ENST00000453464.2
RNF223
ring finger protein 223
chr2_-_160473114 0.17 ENST00000392783.2
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr17_-_74533734 0.17 ENST00000589342.1
CYGB
cytoglobin
chr17_-_39203519 0.17 ENST00000542137.1
ENST00000391419.3
KRTAP2-1
keratin associated protein 2-1
chr3_-_49459865 0.17 ENST00000427987.1
AMT
aminomethyltransferase
chr2_+_43864387 0.16 ENST00000282406.4
PLEKHH2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr10_+_31608054 0.16 ENST00000320985.10
ENST00000361642.5
ENST00000560721.2
ENST00000558440.1
ENST00000424869.1
ENST00000542815.3
ZEB1
zinc finger E-box binding homeobox 1
chr4_-_114682719 0.16 ENST00000394522.3
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr7_-_150675372 0.16 ENST00000262186.5
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr5_+_60240943 0.16 ENST00000296597.5
NDUFAF2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 2
chr3_-_49459878 0.15 ENST00000546031.1
ENST00000458307.2
ENST00000430521.1
AMT
aminomethyltransferase
chr20_+_2517253 0.15 ENST00000358864.1
TMC2
transmembrane channel-like 2
chr17_-_39222131 0.15 ENST00000394015.2
KRTAP2-4
keratin associated protein 2-4
chr2_+_202937972 0.15 ENST00000541917.1
ENST00000295844.3
AC079354.1
uncharacterized protein KIAA2012
chr11_+_73358690 0.15 ENST00000545798.1
ENST00000539157.1
ENST00000546251.1
ENST00000535582.1
ENST00000538227.1
ENST00000543524.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr10_-_98945264 0.15 ENST00000314867.5
SLIT1
slit homolog 1 (Drosophila)
chr11_-_111749767 0.14 ENST00000542429.1
FDXACB1
ferredoxin-fold anticodon binding domain containing 1
chr3_+_107364683 0.14 ENST00000413213.1
BBX
bobby sox homolog (Drosophila)
chr3_+_107364769 0.14 ENST00000449271.1
ENST00000425868.1
ENST00000449213.1
BBX
bobby sox homolog (Drosophila)
chr11_-_85430356 0.14 ENST00000526999.1
SYTL2
synaptotagmin-like 2
chr5_-_114515734 0.14 ENST00000514154.1
ENST00000282369.3
TRIM36
tripartite motif containing 36
chr2_+_37458928 0.14 ENST00000439218.1
ENST00000432075.1
NDUFAF7
NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
chr7_-_127032741 0.14 ENST00000393313.1
ENST00000265827.3
ENST00000434602.1
ZNF800
zinc finger protein 800
chr17_+_30771279 0.14 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
PSMD11
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr11_-_114271139 0.14 ENST00000325636.4
C11orf71
chromosome 11 open reading frame 71
chr11_+_111749942 0.14 ENST00000260276.3
C11orf1
chromosome 11 open reading frame 1
chr6_-_130536774 0.14 ENST00000532763.1
SAMD3
sterile alpha motif domain containing 3
chr2_+_103089756 0.14 ENST00000295269.4
SLC9A4
solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4
chr15_+_76030311 0.14 ENST00000543887.1
AC019294.1
AC019294.1
chr15_-_83474806 0.13 ENST00000541889.1
ENST00000334574.8
ENST00000561368.1
FSD2
fibronectin type III and SPRY domain containing 2
chr11_+_18343800 0.13 ENST00000453096.2
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr14_+_75746781 0.13 ENST00000555347.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr5_+_82767284 0.13 ENST00000265077.3
VCAN
versican
chr2_+_37458776 0.13 ENST00000002125.4
ENST00000336237.6
ENST00000431821.1
NDUFAF7
NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
chr11_-_18343669 0.12 ENST00000396253.3
ENST00000349215.3
ENST00000438420.2
HPS5
Hermansky-Pudlak syndrome 5
chr11_+_74660278 0.12 ENST00000263672.6
ENST00000530257.1
ENST00000526361.1
ENST00000532972.1
SPCS2
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr20_+_11898507 0.12 ENST00000378226.2
BTBD3
BTB (POZ) domain containing 3
chrX_+_46771848 0.11 ENST00000218343.4
PHF16
jade family PHD finger 3
chr2_+_37458904 0.11 ENST00000416653.1
NDUFAF7
NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
chr14_+_75746664 0.11 ENST00000557139.1
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr11_+_18344106 0.11 ENST00000534641.1
ENST00000525831.1
ENST00000265963.4
GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr9_+_140032842 0.10 ENST00000371561.3
ENST00000315048.3
GRIN1
glutamate receptor, ionotropic, N-methyl D-aspartate 1
chr17_+_57970469 0.10 ENST00000443572.2
ENST00000406116.3
ENST00000225577.4
ENST00000393021.3
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr6_-_31080336 0.10 ENST00000259870.3
C6orf15
chromosome 6 open reading frame 15
chr15_+_41913690 0.10 ENST00000563576.1
MGA
MGA, MAX dimerization protein
chr1_-_226076843 0.10 ENST00000272134.5
LEFTY1
left-right determination factor 1
chr1_+_27114418 0.10 ENST00000078527.4
PIGV
phosphatidylinositol glycan anchor biosynthesis, class V
chr4_+_102268904 0.09 ENST00000527564.1
ENST00000529296.1
AP001816.1
Uncharacterized protein
chr1_+_95582881 0.09 ENST00000370203.4
ENST00000456991.1
TMEM56
transmembrane protein 56
chr13_-_46543805 0.09 ENST00000378921.2
ZC3H13
zinc finger CCCH-type containing 13
chr5_+_60241020 0.09 ENST00000511107.1
ENST00000502658.1
NDUFAF2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 2
chr1_-_111148241 0.08 ENST00000440270.1
KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
chr2_-_160472952 0.08 ENST00000541068.2
ENST00000355831.2
ENST00000343439.5
ENST00000392782.1
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr6_-_19804877 0.08 ENST00000447250.1
RP4-625H18.2
RP4-625H18.2
chr1_-_37499726 0.08 ENST00000373091.3
ENST00000373093.4
GRIK3
glutamate receptor, ionotropic, kainate 3
chr17_+_35849937 0.08 ENST00000394389.4
DUSP14
dual specificity phosphatase 14
chr2_-_40680578 0.08 ENST00000455476.1
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr3_+_134514093 0.07 ENST00000398015.3
EPHB1
EPH receptor B1
chr3_+_120626919 0.07 ENST00000273666.6
ENST00000471454.1
ENST00000472879.1
ENST00000497029.1
ENST00000492541.1
STXBP5L
syntaxin binding protein 5-like
chr15_+_76016293 0.07 ENST00000332145.2
ODF3L1
outer dense fiber of sperm tails 3-like 1
chr5_-_34043310 0.07 ENST00000231338.7
C1QTNF3
C1q and tumor necrosis factor related protein 3
chr6_+_39760129 0.07 ENST00000274867.4
DAAM2
dishevelled associated activator of morphogenesis 2
chr11_+_114270752 0.07 ENST00000540163.1
RBM7
RNA binding motif protein 7
chr8_+_56014949 0.07 ENST00000327381.6
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr7_+_133261209 0.06 ENST00000545148.1
EXOC4
exocyst complex component 4
chr11_-_125932685 0.06 ENST00000527967.1
CDON
cell adhesion associated, oncogene regulated
chr22_-_41215291 0.06 ENST00000542412.1
ENST00000544408.1
SLC25A17
solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
chrX_+_70443050 0.06 ENST00000361726.6
GJB1
gap junction protein, beta 1, 32kDa
chr6_+_30295036 0.06 ENST00000376659.5
ENST00000428555.1
TRIM39
tripartite motif containing 39
chr11_+_17568920 0.05 ENST00000399391.2
OTOG
otogelin
chr6_+_79577189 0.05 ENST00000369940.2
IRAK1BP1
interleukin-1 receptor-associated kinase 1 binding protein 1
chr3_-_197024394 0.04 ENST00000434148.1
ENST00000412364.2
ENST00000436682.1
ENST00000456699.2
ENST00000392380.2
DLG1
discs, large homolog 1 (Drosophila)
chr3_+_52422899 0.04 ENST00000480649.1
DNAH1
dynein, axonemal, heavy chain 1
chr2_-_61108449 0.04 ENST00000439412.1
ENST00000452343.1
AC010733.4
AC010733.4
chr12_+_58148842 0.04 ENST00000266643.5
MARCH9
membrane-associated ring finger (C3HC4) 9
chr3_-_133748913 0.04 ENST00000310926.4
SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr2_+_171571827 0.04 ENST00000375281.3
SP5
Sp5 transcription factor
chr3_+_63805017 0.04 ENST00000295896.8
C3orf49
chromosome 3 open reading frame 49
chrX_+_46771711 0.04 ENST00000424392.1
ENST00000397189.1
PHF16
jade family PHD finger 3
chr11_+_86511549 0.04 ENST00000533902.2
PRSS23
protease, serine, 23
chr14_+_21467414 0.03 ENST00000554422.1
ENST00000298681.4
SLC39A2
solute carrier family 39 (zinc transporter), member 2
chr7_-_71801980 0.03 ENST00000329008.5
CALN1
calneuron 1
chr2_+_219081817 0.03 ENST00000315717.5
ENST00000420104.1
ENST00000295685.10
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr9_-_74979420 0.03 ENST00000343431.2
ENST00000376956.3
ZFAND5
zinc finger, AN1-type domain 5
chr1_+_172628154 0.03 ENST00000340030.3
ENST00000367721.2
FASLG
Fas ligand (TNF superfamily, member 6)
chr20_+_44657845 0.03 ENST00000243964.3
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr4_-_140222358 0.03 ENST00000505036.1
ENST00000544855.1
ENST00000539002.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr15_+_92937058 0.03 ENST00000268164.3
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr15_+_36994210 0.03 ENST00000562489.1
C15orf41
chromosome 15 open reading frame 41
chr1_+_206680879 0.03 ENST00000355294.4
ENST00000367117.3
RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr11_-_34535332 0.03 ENST00000257832.2
ENST00000429939.2
ELF5
E74-like factor 5 (ets domain transcription factor)
chr4_-_102268484 0.02 ENST00000394853.4
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr13_-_103053946 0.02 ENST00000376131.4
FGF14
fibroblast growth factor 14
chr11_-_128737163 0.02 ENST00000324003.3
ENST00000392665.2
KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
chr4_-_186456652 0.02 ENST00000284767.5
ENST00000284770.5
PDLIM3
PDZ and LIM domain 3
chr15_-_38852251 0.02 ENST00000558432.1
RASGRP1
RAS guanyl releasing protein 1 (calcium and DAG-regulated)
chr6_+_32132360 0.02 ENST00000333845.6
ENST00000395512.1
ENST00000432129.1
EGFL8
EGF-like-domain, multiple 8
chr4_-_114682597 0.02 ENST00000394524.3
CAMK2D
calcium/calmodulin-dependent protein kinase II delta
chr15_-_58357932 0.02 ENST00000347587.3
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr13_-_36429763 0.02 ENST00000379893.1
DCLK1
doublecortin-like kinase 1
chr10_+_135050908 0.02 ENST00000325980.9
VENTX
VENT homeobox
chr11_+_122709200 0.02 ENST00000227348.4
CRTAM
cytotoxic and regulatory T cell molecule
chr12_-_26278030 0.01 ENST00000242728.4
BHLHE41
basic helix-loop-helix family, member e41
chr6_+_30294612 0.01 ENST00000440271.1
ENST00000396551.3
ENST00000376656.4
ENST00000540416.1
ENST00000428728.1
ENST00000396548.1
ENST00000428404.1
TRIM39
tripartite motif containing 39
chr1_+_26737292 0.01 ENST00000254231.4
LIN28A
lin-28 homolog A (C. elegans)
chr2_+_176972000 0.01 ENST00000249504.5
HOXD11
homeobox D11
chr2_-_175869936 0.01 ENST00000409900.3
CHN1
chimerin 1
chr11_-_34535297 0.01 ENST00000532417.1
ELF5
E74-like factor 5 (ets domain transcription factor)
chr11_-_33913708 0.01 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr17_-_37557846 0.01 ENST00000394294.3
ENST00000583610.1
ENST00000264658.6
FBXL20
F-box and leucine-rich repeat protein 20
chr4_-_186456766 0.01 ENST00000284771.6
PDLIM3
PDZ and LIM domain 3
chr15_+_92937144 0.01 ENST00000539113.1
ENST00000555434.1
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr20_+_44657807 0.01 ENST00000372315.1
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr18_-_53068911 0.00 ENST00000537856.3
TCF4
transcription factor 4
chr4_-_114682936 0.00 ENST00000454265.2
ENST00000429180.1
ENST00000418639.2
ENST00000394526.2
ENST00000296402.5
CAMK2D
calcium/calmodulin-dependent protein kinase II delta

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.1 0.3 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 1.0 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.2 GO:0035621 ER to Golgi ceramide transport(GO:0035621)
0.1 0.6 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.6 GO:0001661 conditioned taste aversion(GO:0001661)
0.1 0.3 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.9 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.1 0.2 GO:0031247 actin rod assembly(GO:0031247)
0.1 0.8 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.3 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.4 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.1 0.2 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.3 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.4 GO:1990034 cellular response to corticosterone stimulus(GO:0071386) calcium ion export from cell(GO:1990034)
0.0 0.3 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.2 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 1.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 0.6 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.0 0.1 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.0 0.2 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.7 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 1.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:0021633 optic nerve structural organization(GO:0021633)
0.0 0.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.2 GO:0070673 response to interleukin-18(GO:0070673)
0.0 2.2 GO:0007422 peripheral nervous system development(GO:0007422)
0.0 0.1 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0046373 arabinose metabolic process(GO:0019566) L-arabinose metabolic process(GO:0046373)
0.0 0.0 GO:0040040 thermosensory behavior(GO:0040040)
0.0 0.0 GO:0043132 coenzyme A transport(GO:0015880) coenzyme A transmembrane transport(GO:0035349) NAD transport(GO:0043132) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.1 0.6 GO:1990357 terminal web(GO:1990357)
0.1 0.5 GO:0035976 AP1 complex(GO:0035976)
0.0 0.3 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.3 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.2 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 1.5 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.2 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.0 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 1.8 GO:0043204 perikaryon(GO:0043204)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.1 GO:0098839 postsynaptic density membrane(GO:0098839)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.1 0.4 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.2 GO:0097001 ceramide binding(GO:0097001)
0.0 0.2 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.9 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 1.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.0 0.1 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 1.7 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.2 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.2 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.3 GO:0005113 patched binding(GO:0005113)
0.0 0.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 2.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.1 GO:0046556 alpha-L-arabinofuranosidase activity(GO:0046556)
0.0 0.0 GO:0071077 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.4 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 2.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.6 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.4 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.5 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.3 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo