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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TBX2

Z-value: 0.88

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Transcription factors associated with TBX2

Gene Symbol Gene ID Gene Info
TBX2
ENSG00000121068.9 T-box transcription factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBX2hg19_v2_chr17_+_59477233_59477263-0.147.9e-01Click!

Activity profile of TBX2 motif

Sorted Z-values of TBX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_615570 2.18 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
IRF7
interferon regulatory factor 7
chr11_-_615942 1.63 ENST00000397562.3
ENST00000330243.5
ENST00000397570.1
ENST00000397574.2
IRF7
interferon regulatory factor 7
chr9_+_96717821 0.74 ENST00000454594.1
RP11-231K24.2
RP11-231K24.2
chr2_-_191878874 0.74 ENST00000392322.3
ENST00000392323.2
ENST00000424722.1
ENST00000361099.3
STAT1
signal transducer and activator of transcription 1, 91kDa
chr8_-_145060593 0.73 ENST00000313059.5
ENST00000524918.1
ENST00000313028.7
ENST00000525773.1
PARP10
poly (ADP-ribose) polymerase family, member 10
chr19_-_10213335 0.64 ENST00000592641.1
ENST00000253109.4
ANGPTL6
angiopoietin-like 6
chr8_-_99955042 0.48 ENST00000519420.1
STK3
serine/threonine kinase 3
chr19_-_51875894 0.43 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
NKG7
natural killer cell group 7 sequence
chr4_+_155484155 0.42 ENST00000509493.1
FGB
fibrinogen beta chain
chr20_-_44516256 0.37 ENST00000372519.3
SPATA25
spermatogenesis associated 25
chr1_+_209878182 0.37 ENST00000367027.3
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr20_+_34020827 0.35 ENST00000374375.1
GDF5OS
growth differentiation factor 5 opposite strand
chr3_+_121554046 0.33 ENST00000273668.2
ENST00000451944.2
EAF2
ELL associated factor 2
chr14_+_95078714 0.33 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr4_+_155484103 0.31 ENST00000302068.4
FGB
fibrinogen beta chain
chr10_+_54074033 0.31 ENST00000373970.3
DKK1
dickkopf WNT signaling pathway inhibitor 1
chr17_-_47925379 0.30 ENST00000352793.2
ENST00000334568.4
ENST00000398154.1
ENST00000436235.1
ENST00000326219.5
TAC4
tachykinin 4 (hemokinin)
chr15_+_89922345 0.30 ENST00000558982.1
LINC00925
long intergenic non-protein coding RNA 925
chr19_-_45748628 0.30 ENST00000590022.1
AC006126.4
AC006126.4
chr2_-_114461655 0.29 ENST00000424612.1
AC017074.2
AC017074.2
chrX_-_119693745 0.28 ENST00000371323.2
CUL4B
cullin 4B
chr10_-_112678692 0.27 ENST00000605742.1
BBIP1
BBSome interacting protein 1
chr10_-_112678904 0.27 ENST00000423273.1
ENST00000436562.1
ENST00000447005.1
ENST00000454061.1
BBIP1
BBSome interacting protein 1
chr11_+_18477369 0.27 ENST00000396213.3
ENST00000280706.2
LDHAL6A
lactate dehydrogenase A-like 6A
chr11_+_73358594 0.27 ENST00000227214.6
ENST00000398494.4
ENST00000543085.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr9_-_34662651 0.26 ENST00000259631.4
CCL27
chemokine (C-C motif) ligand 27
chr5_+_35856951 0.25 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
IL7R
interleukin 7 receptor
chr19_-_55668093 0.25 ENST00000588882.1
ENST00000586858.1
TNNI3
troponin I type 3 (cardiac)
chr11_-_93474645 0.24 ENST00000532455.1
TAF1D
TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
chr11_+_62379194 0.24 ENST00000525801.1
ENST00000534093.1
ROM1
retinal outer segment membrane protein 1
chr4_+_26578293 0.23 ENST00000512840.1
TBC1D19
TBC1 domain family, member 19
chr19_+_50529329 0.23 ENST00000599155.1
ZNF473
zinc finger protein 473
chr2_+_171571827 0.23 ENST00000375281.3
SP5
Sp5 transcription factor
chr8_+_103876528 0.23 ENST00000522939.1
ENST00000524007.1
KB-1507C5.2
HCG15011, isoform CRA_a; Protein LOC100996457
chr9_+_33750515 0.23 ENST00000361005.5
PRSS3
protease, serine, 3
chr10_-_112678976 0.22 ENST00000448814.1
BBIP1
BBSome interacting protein 1
chr7_-_108209897 0.22 ENST00000313516.5
THAP5
THAP domain containing 5
chr4_-_153700864 0.22 ENST00000304337.2
TIGD4
tigger transposable element derived 4
chr10_+_127408263 0.22 ENST00000337623.3
C10orf137
erythroid differentiation regulatory factor 1
chr14_-_35183755 0.22 ENST00000555765.1
CFL2
cofilin 2 (muscle)
chr19_-_51054299 0.21 ENST00000599957.1
LRRC4B
leucine rich repeat containing 4B
chr16_-_4303767 0.21 ENST00000573268.1
ENST00000573042.1
RP11-95P2.1
RP11-95P2.1
chr3_+_167453493 0.21 ENST00000295777.5
ENST00000472747.2
SERPINI1
serpin peptidase inhibitor, clade I (neuroserpin), member 1
chr14_-_69619823 0.20 ENST00000341516.5
DCAF5
DDB1 and CUL4 associated factor 5
chr7_-_100239132 0.20 ENST00000223051.3
ENST00000431692.1
TFR2
transferrin receptor 2
chr2_+_33701286 0.20 ENST00000403687.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr11_+_6260298 0.20 ENST00000379936.2
CNGA4
cyclic nucleotide gated channel alpha 4
chr14_-_69619291 0.19 ENST00000554215.1
ENST00000556847.1
DCAF5
DDB1 and CUL4 associated factor 5
chr19_+_46000506 0.19 ENST00000396737.2
PPM1N
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr3_+_177534653 0.19 ENST00000436078.1
RP11-91K9.1
RP11-91K9.1
chrX_+_16804544 0.19 ENST00000380122.5
ENST00000398155.4
TXLNG
taxilin gamma
chr19_-_44405941 0.19 ENST00000587128.1
RP11-15A1.3
RP11-15A1.3
chr4_-_89619386 0.18 ENST00000323061.5
NAP1L5
nucleosome assembly protein 1-like 5
chr13_-_52027134 0.18 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr13_+_73629107 0.18 ENST00000539231.1
KLF5
Kruppel-like factor 5 (intestinal)
chr22_+_38597889 0.18 ENST00000338483.2
ENST00000538320.1
ENST00000538999.1
ENST00000441709.1
MAFF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr2_+_29033682 0.18 ENST00000379579.4
ENST00000334056.5
ENST00000449210.1
SPDYA
speedy/RINGO cell cycle regulator family member A
chr19_-_51875523 0.18 ENST00000593572.1
ENST00000595157.1
NKG7
natural killer cell group 7 sequence
chr10_-_14596140 0.18 ENST00000496330.1
FAM107B
family with sequence similarity 107, member B
chr5_-_39270725 0.18 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB
FYN binding protein
chr11_+_107643129 0.18 ENST00000447610.1
AP001024.2
Uncharacterized protein
chr3_-_146213722 0.18 ENST00000336685.2
ENST00000489015.1
PLSCR2
phospholipid scramblase 2
chr9_+_131452239 0.17 ENST00000372688.4
ENST00000372686.5
SET
SET nuclear oncogene
chr19_+_50528971 0.17 ENST00000598809.1
ENST00000595661.1
ENST00000391821.2
ZNF473
zinc finger protein 473
chr3_+_32726774 0.17 ENST00000538368.1
CNOT10
CCR4-NOT transcription complex, subunit 10
chr6_+_84222220 0.17 ENST00000369700.3
PRSS35
protease, serine, 35
chr11_-_74204692 0.17 ENST00000528085.1
LIPT2
lipoyl(octanoyl) transferase 2 (putative)
chr2_+_136343904 0.17 ENST00000436436.1
R3HDM1
R3H domain containing 1
chr22_-_31328881 0.17 ENST00000445980.1
MORC2
MORC family CW-type zinc finger 2
chr17_+_48823896 0.16 ENST00000511974.1
LUC7L3
LUC7-like 3 (S. cerevisiae)
chr1_-_28969517 0.16 ENST00000263974.4
ENST00000373824.4
TAF12
TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
chr3_-_120170052 0.15 ENST00000295633.3
FSTL1
follistatin-like 1
chr1_-_85930246 0.15 ENST00000426972.3
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr19_-_44952635 0.15 ENST00000592308.1
ENST00000588931.1
ENST00000291187.4
ZNF229
zinc finger protein 229
chr16_+_69139467 0.15 ENST00000569188.1
HAS3
hyaluronan synthase 3
chr15_-_33180439 0.15 ENST00000559610.1
FMN1
formin 1
chr4_-_114900126 0.15 ENST00000541197.1
ARSJ
arylsulfatase family, member J
chr14_-_35591156 0.14 ENST00000554361.1
PPP2R3C
protein phosphatase 2, regulatory subunit B'', gamma
chr17_-_8027402 0.14 ENST00000541682.2
ENST00000317814.4
ENST00000577735.1
HES7
hes family bHLH transcription factor 7
chr3_-_125094093 0.14 ENST00000484491.1
ENST00000492394.1
ENST00000471196.1
ENST00000468369.1
ENST00000544464.1
ENST00000485866.1
ENST00000360647.4
ZNF148
zinc finger protein 148
chr1_+_26737253 0.14 ENST00000326279.6
LIN28A
lin-28 homolog A (C. elegans)
chr1_+_154975258 0.14 ENST00000417934.2
ZBTB7B
zinc finger and BTB domain containing 7B
chr3_-_119379427 0.14 ENST00000264231.3
ENST00000468801.1
ENST00000538678.1
POPDC2
popeye domain containing 2
chr21_-_46962379 0.13 ENST00000311124.4
ENST00000380010.4
SLC19A1
solute carrier family 19 (folate transporter), member 1
chr17_+_26662679 0.13 ENST00000578158.1
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr2_+_234601512 0.13 ENST00000305139.6
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr5_-_138780159 0.13 ENST00000512473.1
ENST00000515581.1
ENST00000515277.1
DNAJC18
DnaJ (Hsp40) homolog, subfamily C, member 18
chr7_+_144052381 0.13 ENST00000498580.1
ENST00000056217.5
ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr11_+_10772847 0.13 ENST00000524523.1
CTR9
CTR9, Paf1/RNA polymerase II complex component
chr9_+_26956474 0.13 ENST00000429045.2
IFT74
intraflagellar transport 74 homolog (Chlamydomonas)
chr2_+_101223490 0.13 ENST00000414647.1
ENST00000424342.1
AC068538.4
AC068538.4
chr1_-_100231349 0.13 ENST00000287474.5
ENST00000414213.1
FRRS1
ferric-chelate reductase 1
chr14_-_24664540 0.13 ENST00000530563.1
ENST00000528895.1
ENST00000528669.1
ENST00000532632.1
TM9SF1
transmembrane 9 superfamily member 1
chr3_-_49726486 0.13 ENST00000449682.2
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr11_+_117947724 0.13 ENST00000534111.1
TMPRSS4
transmembrane protease, serine 4
chr2_-_175869936 0.13 ENST00000409900.3
CHN1
chimerin 1
chr1_-_205290865 0.13 ENST00000367157.3
NUAK2
NUAK family, SNF1-like kinase, 2
chr11_+_58938903 0.13 ENST00000532982.1
DTX4
deltex homolog 4 (Drosophila)
chr13_+_76378305 0.13 ENST00000526371.1
ENST00000526528.1
LMO7
LIM domain 7
chr2_+_105953972 0.12 ENST00000410049.1
C2orf49
chromosome 2 open reading frame 49
chr8_-_19459993 0.12 ENST00000454498.2
ENST00000520003.1
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr11_+_118842417 0.12 ENST00000317011.3
FOXR1
forkhead box R1
chr9_+_131447342 0.12 ENST00000409104.3
SET
SET nuclear oncogene
chr16_+_72459838 0.12 ENST00000564508.1
AC004158.3
AC004158.3
chr19_+_37407212 0.12 ENST00000427117.1
ENST00000587130.1
ENST00000333987.7
ENST00000415168.1
ENST00000444991.1
ZNF568
zinc finger protein 568
chr6_+_160221293 0.12 ENST00000610273.1
ENST00000392167.3
PNLDC1
poly(A)-specific ribonuclease (PARN)-like domain containing 1
chr1_+_9599540 0.12 ENST00000302692.6
SLC25A33
solute carrier family 25 (pyrimidine nucleotide carrier), member 33
chr12_-_46385811 0.12 ENST00000419565.2
SCAF11
SR-related CTD-associated factor 11
chr19_-_44174305 0.12 ENST00000601723.1
ENST00000339082.3
PLAUR
plasminogen activator, urokinase receptor
chr19_-_44174330 0.12 ENST00000340093.3
PLAUR
plasminogen activator, urokinase receptor
chr19_-_43702231 0.11 ENST00000597374.1
ENST00000599371.1
PSG4
pregnancy specific beta-1-glycoprotein 4
chrX_+_102862834 0.11 ENST00000372627.5
ENST00000243286.3
TCEAL3
transcription elongation factor A (SII)-like 3
chr11_+_114270752 0.11 ENST00000540163.1
RBM7
RNA binding motif protein 7
chr11_+_86667117 0.11 ENST00000531827.1
RP11-736K20.6
RP11-736K20.6
chr19_+_50529212 0.11 ENST00000270617.3
ENST00000445728.3
ENST00000601364.1
ZNF473
zinc finger protein 473
chr14_+_21525981 0.11 ENST00000308227.2
RNASE8
ribonuclease, RNase A family, 8
chr8_+_1993173 0.11 ENST00000523438.1
MYOM2
myomesin 2
chr10_+_127512106 0.11 ENST00000278100.6
ENST00000299130.3
ENST00000368759.5
ENST00000429863.2
BCCIP
BRCA2 and CDKN1A interacting protein
chr19_-_15529790 0.11 ENST00000596195.1
ENST00000595067.1
ENST00000595465.2
ENST00000397410.5
ENST00000600247.1
AKAP8L
A kinase (PRKA) anchor protein 8-like
chr2_+_234875252 0.11 ENST00000456930.1
TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr2_+_136343943 0.11 ENST00000409606.1
R3HDM1
R3H domain containing 1
chr7_+_108210012 0.11 ENST00000249356.3
DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr17_+_26662730 0.11 ENST00000226225.2
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr9_-_20622478 0.11 ENST00000355930.6
ENST00000380338.4
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr5_-_133706695 0.11 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
CDKL3
cyclin-dependent kinase-like 3
chr17_+_39868577 0.11 ENST00000329402.3
GAST
gastrin
chr19_-_45737469 0.10 ENST00000413988.1
EXOC3L2
exocyst complex component 3-like 2
chr4_+_140222609 0.10 ENST00000296543.5
ENST00000398947.1
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr1_+_35246775 0.10 ENST00000373366.2
GJB3
gap junction protein, beta 3, 31kDa
chr12_+_50794891 0.10 ENST00000517559.1
LARP4
La ribonucleoprotein domain family, member 4
chr2_-_39664405 0.10 ENST00000341681.5
ENST00000263881.3
MAP4K3
mitogen-activated protein kinase kinase kinase kinase 3
chr1_-_25256368 0.10 ENST00000308873.6
RUNX3
runt-related transcription factor 3
chr19_+_18492973 0.10 ENST00000595973.2
GDF15
growth differentiation factor 15
chr2_-_136743436 0.10 ENST00000441323.1
ENST00000449218.1
DARS
aspartyl-tRNA synthetase
chr1_+_35734562 0.10 ENST00000314607.6
ENST00000373297.2
ZMYM4
zinc finger, MYM-type 4
chr12_+_1099675 0.10 ENST00000545318.2
ERC1
ELKS/RAB6-interacting/CAST family member 1
chr6_+_121756809 0.10 ENST00000282561.3
GJA1
gap junction protein, alpha 1, 43kDa
chr2_+_120770645 0.10 ENST00000443902.2
EPB41L5
erythrocyte membrane protein band 4.1 like 5
chr5_+_81601166 0.10 ENST00000439350.1
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr5_-_137610300 0.10 ENST00000274721.3
GFRA3
GDNF family receptor alpha 3
chr2_-_120124258 0.10 ENST00000409877.1
ENST00000409523.1
ENST00000409466.2
ENST00000414534.1
C2orf76
chromosome 2 open reading frame 76
chr2_+_53994927 0.10 ENST00000295304.4
CHAC2
ChaC, cation transport regulator homolog 2 (E. coli)
chr7_-_76255444 0.10 ENST00000454397.1
POMZP3
POM121 and ZP3 fusion
chr1_+_35225339 0.10 ENST00000339480.1
GJB4
gap junction protein, beta 4, 30.3kDa
chr7_+_34697973 0.10 ENST00000381539.3
NPSR1
neuropeptide S receptor 1
chr19_-_39108643 0.10 ENST00000396857.2
MAP4K1
mitogen-activated protein kinase kinase kinase kinase 1
chr2_-_31637560 0.10 ENST00000379416.3
XDH
xanthine dehydrogenase
chr3_+_124355944 0.10 ENST00000459915.1
KALRN
kalirin, RhoGEF kinase
chr10_-_102790852 0.10 ENST00000470414.1
ENST00000370215.3
PDZD7
PDZ domain containing 7
chrX_-_119709637 0.10 ENST00000404115.3
CUL4B
cullin 4B
chr14_-_23446900 0.09 ENST00000556731.1
AJUBA
ajuba LIM protein
chr3_-_66551397 0.09 ENST00000383703.3
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr20_-_1165319 0.09 ENST00000429036.1
TMEM74B
transmembrane protein 74B
chr2_-_148778323 0.09 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
ORC4
origin recognition complex, subunit 4
chr1_+_154975110 0.09 ENST00000535420.1
ENST00000368426.3
ZBTB7B
zinc finger and BTB domain containing 7B
chr1_-_240775447 0.09 ENST00000318160.4
GREM2
gremlin 2, DAN family BMP antagonist
chr10_-_125853200 0.09 ENST00000421115.1
CHST15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr12_+_32112340 0.09 ENST00000540924.1
ENST00000312561.4
KIAA1551
KIAA1551
chr14_-_69619689 0.09 ENST00000389997.6
ENST00000557386.1
ENST00000554681.1
DCAF5
DDB1 and CUL4 associated factor 5
chr12_+_58148842 0.09 ENST00000266643.5
MARCH9
membrane-associated ring finger (C3HC4) 9
chr17_-_1029866 0.09 ENST00000570525.1
ABR
active BCR-related
chr11_-_85779971 0.09 ENST00000393346.3
PICALM
phosphatidylinositol binding clathrin assembly protein
chr3_+_148447887 0.09 ENST00000475347.1
ENST00000474935.1
ENST00000461609.1
AGTR1
angiotensin II receptor, type 1
chr19_-_36001286 0.09 ENST00000602679.1
ENST00000492341.2
ENST00000472252.2
ENST00000602781.1
ENST00000402589.2
ENST00000458071.1
ENST00000436012.1
ENST00000443640.1
ENST00000450261.1
ENST00000467637.1
ENST00000480502.1
ENST00000474928.1
ENST00000414866.2
ENST00000392206.2
ENST00000488892.1
DMKN
dermokine
chr9_-_32552551 0.09 ENST00000360538.2
ENST00000379858.1
TOPORS
topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
chr1_+_93544821 0.09 ENST00000370303.4
MTF2
metal response element binding transcription factor 2
chr13_-_49975632 0.09 ENST00000457041.1
ENST00000355854.4
CAB39L
calcium binding protein 39-like
chr5_-_102898465 0.09 ENST00000507423.1
ENST00000230792.2
NUDT12
nudix (nucleoside diphosphate linked moiety X)-type motif 12
chr21_-_35884573 0.09 ENST00000399286.2
KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr14_-_55658323 0.09 ENST00000554067.1
ENST00000247191.2
DLGAP5
discs, large (Drosophila) homolog-associated protein 5
chr12_+_52430894 0.09 ENST00000546842.1
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr4_+_141445311 0.09 ENST00000323570.3
ENST00000511887.2
ELMOD2
ELMO/CED-12 domain containing 2
chr8_+_82192501 0.09 ENST00000297258.6
FABP5
fatty acid binding protein 5 (psoriasis-associated)
chr20_-_271009 0.09 ENST00000382369.5
C20orf96
chromosome 20 open reading frame 96
chr7_+_35840542 0.09 ENST00000435235.1
ENST00000399034.2
ENST00000350320.6
ENST00000469679.2
SEPT7
septin 7
chr17_+_76210367 0.09 ENST00000592734.1
ENST00000587746.1
BIRC5
baculoviral IAP repeat containing 5
chr6_+_292253 0.08 ENST00000603453.1
ENST00000605315.1
ENST00000603881.1
DUSP22
dual specificity phosphatase 22
chr3_+_32726620 0.08 ENST00000331889.6
ENST00000328834.5
CNOT10
CCR4-NOT transcription complex, subunit 10
chr1_-_245026388 0.08 ENST00000440865.1
HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr14_-_45603657 0.08 ENST00000396062.3
FKBP3
FK506 binding protein 3, 25kDa
chr19_+_53761545 0.08 ENST00000341702.3
VN1R2
vomeronasal 1 receptor 2
chr5_+_102090974 0.08 ENST00000512073.1
PAM
peptidylglycine alpha-amidating monooxygenase
chr22_-_41215291 0.08 ENST00000542412.1
ENST00000544408.1
SLC25A17
solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
chr19_+_13049413 0.08 ENST00000316448.5
ENST00000588454.1
CALR
calreticulin
chr3_-_119379719 0.08 ENST00000493094.1
POPDC2
popeye domain containing 2
chr9_+_40028620 0.08 ENST00000426179.1
AL353791.1
AL353791.1
chr1_+_155099927 0.08 ENST00000368407.3
EFNA1
ephrin-A1
chr13_-_48669232 0.08 ENST00000258648.2
ENST00000378586.1
MED4
mediator complex subunit 4
chr3_-_66551351 0.08 ENST00000273261.3
LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chr22_+_38201114 0.08 ENST00000340857.2
H1F0
H1 histone family, member 0
chr6_+_391739 0.08 ENST00000380956.4
IRF4
interferon regulatory factor 4
chr22_-_38699003 0.08 ENST00000451964.1
CSNK1E
casein kinase 1, epsilon
chr16_-_88717423 0.08 ENST00000568278.1
ENST00000569359.1
ENST00000567174.1
CYBA
cytochrome b-245, alpha polypeptide
chr10_+_95256356 0.08 ENST00000371485.3
CEP55
centrosomal protein 55kDa
chr5_+_64859066 0.07 ENST00000261308.5
ENST00000535264.1
ENST00000538977.1
PPWD1
peptidylprolyl isomerase domain and WD repeat containing 1
chr17_-_60005329 0.07 ENST00000251334.6
INTS2
integrator complex subunit 2
chr6_-_160166218 0.07 ENST00000537657.1
SOD2
superoxide dismutase 2, mitochondrial
chr19_+_18529674 0.07 ENST00000597724.2
SSBP4
single stranded DNA binding protein 4
chr7_+_27282319 0.07 ENST00000222761.3
EVX1
even-skipped homeobox 1
chr10_+_47746929 0.07 ENST00000340243.6
ENST00000374277.5
ENST00000449464.2
ENST00000538825.1
ENST00000335083.5
ANXA8L2
AL603965.1
annexin A8-like 2
Protein LOC100996760

Network of associatons between targets according to the STRING database.

First level regulatory network of TBX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.2 0.7 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.1 0.7 GO:0010847 regulation of chromatin assembly(GO:0010847) protein auto-ADP-ribosylation(GO:0070213)
0.1 0.4 GO:0100012 negative regulation of mesodermal cell fate specification(GO:0042662) regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012)
0.1 0.5 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 0.8 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 0.7 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.3 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.1 0.2 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 0.5 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.2 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.0 0.1 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.1 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.2 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.0 0.2 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.1 GO:1903367 cell communication by chemical coupling(GO:0010643) positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.0 0.1 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.0 0.1 GO:0007509 mesoderm migration involved in gastrulation(GO:0007509)
0.0 0.3 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.1 GO:0002309 T cell proliferation involved in immune response(GO:0002309)
0.0 0.1 GO:0019364 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.0 0.2 GO:0038195 urokinase plasminogen activator signaling pathway(GO:0038195)
0.0 0.1 GO:0061760 antifungal innate immune response(GO:0061760)
0.0 0.1 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.0 0.2 GO:0016476 regulation of embryonic cell shape(GO:0016476)
0.0 0.1 GO:0006429 glutaminyl-tRNA aminoacylation(GO:0006425) leucyl-tRNA aminoacylation(GO:0006429)
0.0 0.1 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.1 GO:0046110 xanthine metabolic process(GO:0046110)
0.0 0.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.1 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.1 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.0 0.3 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0002325 natural killer cell differentiation involved in immune response(GO:0002325) regulation of natural killer cell differentiation involved in immune response(GO:0032826)
0.0 0.0 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.1 GO:0061101 neuroendocrine cell differentiation(GO:0061101)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.0 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.1 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.0 0.1 GO:1990502 dense core granule maturation(GO:1990502)
0.0 0.3 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.1 GO:0035803 egg coat formation(GO:0035803)
0.0 0.0 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 0.4 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.3 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.1 GO:0003068 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:0000412 histone peptidyl-prolyl isomerization(GO:0000412)
0.0 0.1 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.0 0.1 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.0 0.1 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0 0.2 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.2 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.2 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.0 0.1 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.1 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.3 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.0 GO:0019417 sulfur oxidation(GO:0019417)
0.0 0.1 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.1 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.0 GO:0045210 negative regulation of dendritic cell cytokine production(GO:0002731) FasL biosynthetic process(GO:0045210)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 0.2 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.1 0.7 GO:0034464 BBSome(GO:0034464)
0.1 0.7 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0036117 hyaluranon cable(GO:0036117)
0.0 0.3 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.4 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.0 0.0 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.0 0.1 GO:0019867 outer membrane(GO:0019867)
0.0 0.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.0 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.0 GO:0097181 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.0 0.1 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.0 GO:0089701 U2AF(GO:0089701)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.3 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.1 0.3 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 0.3 GO:0030172 troponin C binding(GO:0030172)
0.1 0.2 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.1 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.1 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.2 GO:0030377 urokinase plasminogen activator receptor activity(GO:0030377)
0.0 4.5 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.3 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.1 GO:0004823 glutamine-tRNA ligase activity(GO:0004819) leucine-tRNA ligase activity(GO:0004823)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0005018 platelet-derived growth factor alpha-receptor activity(GO:0005018)
0.0 0.1 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.1 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.9 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.1 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 0.1 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.0 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0 0.0 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.1 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.1 GO:0031433 telethonin binding(GO:0031433)
0.0 0.1 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.0 0.0 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.0 0.1 GO:0008184 nucleobase binding(GO:0002054) purine nucleobase binding(GO:0002060) glycogen phosphorylase activity(GO:0008184)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.1 GO:0070643 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.0 0.1 GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 0.1 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.0 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.1 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.0 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 3.8 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.9 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.8 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.8 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.5 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo