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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for TBP

Z-value: 2.69

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Transcription factors associated with TBP

Gene Symbol Gene ID Gene Info
TBP
ENSG00000112592.8 TATA-box binding protein

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TBPhg19_v2_chr6_+_170863353_1708633900.721.1e-01Click!

Activity profile of TBP motif

Sorted Z-values of TBP motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_615570 3.36 ENST00000525445.1
ENST00000348655.6
ENST00000397566.1
IRF7
interferon regulatory factor 7
chr10_+_91152303 3.30 ENST00000371804.3
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr6_-_26189304 2.36 ENST00000340756.2
HIST1H4D
histone cluster 1, H4d
chr9_-_35658007 2.17 ENST00000602361.1
RMRP
RNA component of mitochondrial RNA processing endoribonuclease
chr6_+_26104104 2.14 ENST00000377803.2
HIST1H4C
histone cluster 1, H4c
chr16_+_2014993 2.11 ENST00000564014.1
SNHG9
small nucleolar RNA host gene 9 (non-protein coding)
chr6_-_26043885 2.05 ENST00000357905.2
HIST1H2BB
histone cluster 1, H2bb
chr10_+_91087651 1.68 ENST00000371818.4
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr12_-_121476959 1.61 ENST00000339275.5
OASL
2'-5'-oligoadenylate synthetase-like
chr6_+_26156551 1.60 ENST00000304218.3
HIST1H1E
histone cluster 1, H1e
chr4_-_169239921 1.57 ENST00000514995.1
ENST00000393743.3
DDX60
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr11_+_18287721 1.49 ENST00000356524.4
SAA1
serum amyloid A1
chr12_-_121477039 1.46 ENST00000257570.5
OASL
2'-5'-oligoadenylate synthetase-like
chr6_+_27107053 1.38 ENST00000354348.2
HIST1H4I
histone cluster 1, H4i
chr6_+_26045603 1.36 ENST00000540144.1
HIST1H3C
histone cluster 1, H3c
chr17_-_39023462 1.30 ENST00000251643.4
KRT12
keratin 12
chr6_+_27114861 1.28 ENST00000377459.1
HIST1H2AH
histone cluster 1, H2ah
chr6_-_26235206 1.25 ENST00000244534.5
HIST1H1D
histone cluster 1, H1d
chr1_-_149785236 1.22 ENST00000331491.1
HIST2H3D
histone cluster 2, H3d
chr1_+_33546714 1.17 ENST00000294517.6
ENST00000358680.3
ENST00000373443.3
ENST00000398167.1
ADC
arginine decarboxylase
chr17_-_34207295 1.15 ENST00000463941.1
ENST00000293272.3
CCL5
chemokine (C-C motif) ligand 5
chr6_+_26217159 1.15 ENST00000303910.2
HIST1H2AE
histone cluster 1, H2ae
chr16_-_67965756 1.14 ENST00000571044.1
ENST00000571605.1
CTRL
chymotrypsin-like
chr12_-_118796971 1.10 ENST00000542902.1
TAOK3
TAO kinase 3
chr11_-_1619524 1.10 ENST00000412090.1
KRTAP5-2
keratin associated protein 5-2
chr11_+_18287801 1.07 ENST00000532858.1
ENST00000405158.2
SAA1
serum amyloid A1
chr19_-_6720686 1.04 ENST00000245907.6
C3
complement component 3
chr1_+_153330322 1.00 ENST00000368738.3
S100A9
S100 calcium binding protein A9
chr7_-_92777606 0.99 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr4_-_74904398 0.98 ENST00000296026.4
CXCL3
chemokine (C-X-C motif) ligand 3
chr18_+_68002675 0.93 ENST00000584919.1
RP11-41O4.1
Uncharacterized protein
chr3_-_170588163 0.89 ENST00000295830.8
RPL22L1
ribosomal protein L22-like 1
chr17_+_39411636 0.88 ENST00000394008.1
KRTAP9-9
keratin associated protein 9-9
chr6_-_27840099 0.86 ENST00000328488.2
HIST1H3I
histone cluster 1, H3i
chr16_+_2014941 0.85 ENST00000531523.1
SNHG9
small nucleolar RNA host gene 9 (non-protein coding)
chr17_+_80186908 0.80 ENST00000582743.1
ENST00000578684.1
ENST00000577650.1
ENST00000582715.1
SLC16A3
solute carrier family 16 (monocarboxylate transporter), member 3
chr9_+_92219919 0.80 ENST00000252506.6
ENST00000375769.1
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr14_-_50506589 0.80 ENST00000553914.2
RP11-58E21.3
RP11-58E21.3
chr1_-_220101944 0.80 ENST00000366926.3
ENST00000536992.1
SLC30A10
solute carrier family 30, member 10
chr7_-_75401513 0.77 ENST00000005180.4
CCL26
chemokine (C-C motif) ligand 26
chr4_+_74702214 0.77 ENST00000226317.5
ENST00000515050.1
CXCL6
chemokine (C-X-C motif) ligand 6
chr12_+_52695617 0.76 ENST00000293525.5
KRT86
keratin 86
chr1_-_228613026 0.76 ENST00000366696.1
HIST3H3
histone cluster 3, H3
chr17_+_39421591 0.75 ENST00000391355.1
KRTAP9-6
keratin associated protein 9-6
chr9_+_130911723 0.73 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2
lipocalin 2
chr4_+_74735102 0.70 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chrX_-_133792480 0.69 ENST00000359237.4
PLAC1
placenta-specific 1
chr4_-_74853897 0.68 ENST00000296028.3
PPBP
pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
chr6_+_159290917 0.67 ENST00000367072.1
C6orf99
chromosome 6 open reading frame 99
chr19_+_10381769 0.67 ENST00000423829.2
ENST00000588645.1
ICAM1
intercellular adhesion molecule 1
chr6_-_27841289 0.66 ENST00000355981.2
HIST1H4L
histone cluster 1, H4l
chr3_-_170587815 0.66 ENST00000466674.1
RPL22L1
ribosomal protein L22-like 1
chr9_+_130911770 0.66 ENST00000372998.1
LCN2
lipocalin 2
chr19_+_36347787 0.64 ENST00000347900.6
ENST00000360202.5
KIRREL2
kin of IRRE like 2 (Drosophila)
chr17_+_74729060 0.61 ENST00000587459.1
RP11-318A15.7
Uncharacterized protein
chr1_-_89488510 0.60 ENST00000564665.1
ENST00000370481.4
GBP3
guanylate binding protein 3
chr4_+_74606223 0.59 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr1_-_16763911 0.58 ENST00000375577.1
ENST00000335496.1
SPATA21
spermatogenesis associated 21
chr18_-_61329118 0.57 ENST00000332821.8
ENST00000283752.5
SERPINB3
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr22_+_19706958 0.57 ENST00000395109.2
SEPT5
septin 5
chr17_-_38928414 0.56 ENST00000335552.4
KRT26
keratin 26
chr3_+_57882061 0.56 ENST00000461354.1
ENST00000466255.1
SLMAP
sarcolemma associated protein
chr19_-_53636125 0.56 ENST00000601493.1
ENST00000599261.1
ENST00000597503.1
ENST00000500065.4
ENST00000243643.4
ENST00000594011.1
ENST00000455735.2
ENST00000595193.1
ENST00000448501.1
ENST00000421033.1
ENST00000440291.1
ENST00000595813.1
ENST00000600574.1
ENST00000596051.1
ENST00000601110.1
ZNF415
zinc finger protein 415
chr3_+_149192475 0.55 ENST00000465758.1
TM4SF4
transmembrane 4 L six family member 4
chr11_+_45168182 0.55 ENST00000526442.1
PRDM11
PR domain containing 11
chr7_+_6121296 0.54 ENST00000428901.1
AC004895.4
AC004895.4
chr16_+_57406368 0.54 ENST00000006053.6
ENST00000563383.1
CX3CL1
chemokine (C-X3-C motif) ligand 1
chr17_+_76183398 0.54 ENST00000409257.5
AFMID
arylformamidase
chr11_-_102651343 0.54 ENST00000279441.4
ENST00000539681.1
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr14_+_56127960 0.52 ENST00000553624.1
KTN1
kinectin 1 (kinesin receptor)
chr3_-_170587974 0.52 ENST00000463836.1
RPL22L1
ribosomal protein L22-like 1
chr6_-_26197478 0.51 ENST00000356476.2
HIST1H3D
histone cluster 1, H3d
chr12_+_11905413 0.51 ENST00000545027.1
ETV6
ets variant 6
chr10_+_54074033 0.51 ENST00000373970.3
DKK1
dickkopf WNT signaling pathway inhibitor 1
chr6_+_27833034 0.50 ENST00000357320.2
HIST1H2AL
histone cluster 1, H2al
chr15_-_41166414 0.49 ENST00000220507.4
RHOV
ras homolog family member V
chr2_+_33661382 0.48 ENST00000402538.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr14_+_56127989 0.47 ENST00000555573.1
KTN1
kinectin 1 (kinesin receptor)
chr17_+_76183432 0.47 ENST00000591256.1
ENST00000589256.1
ENST00000588800.1
ENST00000591952.1
ENST00000327898.5
ENST00000586542.1
ENST00000586731.1
AFMID
arylformamidase
chr6_-_76203345 0.47 ENST00000393004.2
FILIP1
filamin A interacting protein 1
chr20_+_30193083 0.46 ENST00000376112.3
ENST00000376105.3
ID1
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
chr4_+_108815402 0.46 ENST00000503385.1
SGMS2
sphingomyelin synthase 2
chr10_+_48247669 0.45 ENST00000457620.1
FAM25G
family with sequence similarity 25, member G
chr1_-_156675564 0.45 ENST00000368220.1
CRABP2
cellular retinoic acid binding protein 2
chr1_+_37940153 0.45 ENST00000373087.6
ZC3H12A
zinc finger CCCH-type containing 12A
chr10_-_47181681 0.45 ENST00000452267.1
FAM25B
family with sequence similarity 25, member B
chr18_-_53735601 0.45 ENST00000589754.1
CTD-2008L17.2
CTD-2008L17.2
chr6_-_26032288 0.44 ENST00000244661.2
HIST1H3B
histone cluster 1, H3b
chr7_+_75024337 0.44 ENST00000450434.1
TRIM73
tripartite motif containing 73
chr1_+_43424698 0.43 ENST00000431759.1
SLC2A1-AS1
SLC2A1 antisense RNA 1
chr2_+_39893043 0.43 ENST00000281961.2
TMEM178A
transmembrane protein 178A
chr1_+_198189921 0.42 ENST00000391974.3
NEK7
NIMA-related kinase 7
chr19_+_496454 0.42 ENST00000346144.4
ENST00000215637.3
ENST00000382683.4
MADCAM1
mucosal vascular addressin cell adhesion molecule 1
chr9_+_138413277 0.42 ENST00000263598.2
ENST00000371781.3
LCN1
lipocalin 1
chr8_+_145321517 0.41 ENST00000340210.1
SCXB
scleraxis homolog B (mouse)
chr19_+_46367518 0.41 ENST00000302177.2
FOXA3
forkhead box A3
chr12_-_118796910 0.40 ENST00000541186.1
ENST00000539872.1
TAOK3
TAO kinase 3
chr6_+_27861190 0.40 ENST00000303806.4
HIST1H2BO
histone cluster 1, H2bo
chr6_-_52859968 0.39 ENST00000370959.1
GSTA4
glutathione S-transferase alpha 4
chr6_-_78173490 0.39 ENST00000369947.2
HTR1B
5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
chr17_-_39341594 0.39 ENST00000398472.1
KRTAP4-1
keratin associated protein 4-1
chr15_+_45722727 0.39 ENST00000396650.2
ENST00000558435.1
ENST00000344300.3
C15orf48
chromosome 15 open reading frame 48
chr1_+_92414952 0.39 ENST00000449584.1
ENST00000427104.1
ENST00000355011.3
ENST00000448194.1
ENST00000426141.1
ENST00000450792.1
ENST00000548992.1
ENST00000552654.1
ENST00000457265.1
BRDT
bromodomain, testis-specific
chr4_-_140098339 0.39 ENST00000394235.2
ELF2
E74-like factor 2 (ets domain transcription factor)
chr7_+_107301447 0.38 ENST00000440056.1
SLC26A4
solute carrier family 26 (anion exchanger), member 4
chr16_+_2880369 0.38 ENST00000572863.1
ZG16B
zymogen granule protein 16B
chr11_+_64937625 0.38 ENST00000377185.2
SPDYC
speedy/RINGO cell cycle regulator family member C
chr5_-_57756087 0.37 ENST00000274289.3
PLK2
polo-like kinase 2
chr5_-_34043310 0.37 ENST00000231338.7
C1QTNF3
C1q and tumor necrosis factor related protein 3
chr19_+_4769117 0.37 ENST00000540211.1
ENST00000317292.3
ENST00000586721.1
ENST00000592709.1
ENST00000588711.1
ENST00000589639.1
ENST00000591008.1
ENST00000592663.1
ENST00000588758.1
MIR7-3HG
MIR7-3 host gene (non-protein coding)
chr18_+_21718924 0.37 ENST00000399496.3
CABYR
calcium binding tyrosine-(Y)-phosphorylation regulated
chr3_-_131756559 0.37 ENST00000505957.1
CPNE4
copine IV
chr3_+_101546827 0.37 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr12_-_11184006 0.37 ENST00000390675.2
TAS2R31
taste receptor, type 2, member 31
chr17_-_73150629 0.37 ENST00000356033.4
ENST00000405458.3
ENST00000409753.3
HN1
hematological and neurological expressed 1
chr10_+_7745232 0.36 ENST00000358415.4
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr19_-_8386238 0.36 ENST00000301457.2
NDUFA7
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
chr10_-_74856608 0.36 ENST00000307116.2
ENST00000373008.2
ENST00000412021.2
ENST00000394890.2
ENST00000263556.3
ENST00000440381.1
P4HA1
prolyl 4-hydroxylase, alpha polypeptide I
chr1_-_11907829 0.36 ENST00000376480.3
NPPA
natriuretic peptide A
chr6_+_159291090 0.36 ENST00000367073.4
ENST00000608817.1
C6orf99
chromosome 6 open reading frame 99
chr7_-_7575477 0.35 ENST00000399429.3
COL28A1
collagen, type XXVIII, alpha 1
chr14_+_65007177 0.35 ENST00000247207.6
HSPA2
heat shock 70kDa protein 2
chr19_+_840963 0.35 ENST00000234347.5
PRTN3
proteinase 3
chrX_-_119077695 0.34 ENST00000371410.3
NKAP
NFKB activating protein
chr19_+_13049413 0.34 ENST00000316448.5
ENST00000588454.1
CALR
calreticulin
chr1_-_179457805 0.34 ENST00000600581.1
AL160286.1
Uncharacterized protein
chrX_+_18725758 0.33 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
PPEF1
protein phosphatase, EF-hand calcium binding domain 1
chr5_-_79946820 0.33 ENST00000604882.1
MTRNR2L2
MT-RNR2-like 2
chr8_+_86089460 0.33 ENST00000418930.2
E2F5
E2F transcription factor 5, p130-binding
chr22_-_40929812 0.32 ENST00000422851.1
MKL1
megakaryoblastic leukemia (translocation) 1
chr6_+_64281906 0.32 ENST00000370651.3
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr6_-_26018007 0.32 ENST00000244573.3
HIST1H1A
histone cluster 1, H1a
chr7_+_108210012 0.32 ENST00000249356.3
DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr6_-_26199499 0.32 ENST00000377831.5
HIST1H3D
histone cluster 1, H3d
chr19_-_33793430 0.32 ENST00000498907.2
CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr11_-_102714534 0.32 ENST00000299855.5
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr12_-_21757774 0.30 ENST00000261195.2
GYS2
glycogen synthase 2 (liver)
chr19_+_46732988 0.29 ENST00000437936.1
IGFL1
IGF-like family member 1
chr5_-_153857819 0.29 ENST00000231121.2
HAND1
heart and neural crest derivatives expressed 1
chr2_-_224467093 0.29 ENST00000305409.2
SCG2
secretogranin II
chr1_-_8086343 0.29 ENST00000474874.1
ENST00000469499.1
ENST00000377482.5
ERRFI1
ERBB receptor feedback inhibitor 1
chr3_-_96337000 0.29 ENST00000600213.2
MTRNR2L12
MT-RNR2-like 12 (pseudogene)
chr10_-_94301107 0.29 ENST00000436178.1
IDE
insulin-degrading enzyme
chrX_-_119445306 0.28 ENST00000371369.4
ENST00000440464.1
ENST00000519908.1
TMEM255A
transmembrane protein 255A
chr6_-_26199471 0.27 ENST00000341023.1
HIST1H2AD
histone cluster 1, H2ad
chr11_-_62432641 0.27 ENST00000528405.1
ENST00000524958.1
ENST00000525675.1
RP11-831H9.11
C11orf48
Uncharacterized protein
chromosome 11 open reading frame 48
chr1_-_116926718 0.27 ENST00000598661.1
AL136376.1
Uncharacterized protein
chr7_+_29186174 0.26 ENST00000439384.1
CHN2
chimerin 2
chr9_-_33447584 0.26 ENST00000297991.4
AQP3
aquaporin 3 (Gill blood group)
chr1_-_42630389 0.26 ENST00000357001.2
GUCA2A
guanylate cyclase activator 2A (guanylin)
chr10_+_112327425 0.26 ENST00000361804.4
SMC3
structural maintenance of chromosomes 3
chr7_-_55640141 0.25 ENST00000452832.1
VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
chrX_+_41548220 0.25 ENST00000378142.4
GPR34
G protein-coupled receptor 34
chr10_+_6130946 0.25 ENST00000379888.4
RBM17
RNA binding motif protein 17
chr11_-_9025541 0.25 ENST00000525100.1
ENST00000309166.3
ENST00000531090.1
NRIP3
nuclear receptor interacting protein 3
chr6_+_136172820 0.25 ENST00000308191.6
PDE7B
phosphodiesterase 7B
chr7_+_133615169 0.24 ENST00000541309.1
EXOC4
exocyst complex component 4
chr13_+_43597269 0.24 ENST00000379221.2
DNAJC15
DnaJ (Hsp40) homolog, subfamily C, member 15
chr21_-_43735446 0.24 ENST00000398431.2
TFF3
trefoil factor 3 (intestinal)
chr19_+_12944722 0.24 ENST00000591495.1
MAST1
microtubule associated serine/threonine kinase 1
chr1_+_17575584 0.24 ENST00000375460.3
PADI3
peptidyl arginine deiminase, type III
chr8_+_1993152 0.24 ENST00000262113.4
MYOM2
myomesin 2
chr6_+_64282447 0.24 ENST00000370650.2
ENST00000578299.1
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr21_+_33031935 0.24 ENST00000270142.6
ENST00000389995.4
SOD1
superoxide dismutase 1, soluble
chr22_+_19466980 0.23 ENST00000407835.1
ENST00000438587.1
CDC45
cell division cycle 45
chr2_+_85132749 0.23 ENST00000233143.4
TMSB10
thymosin beta 10
chr1_-_169703203 0.23 ENST00000333360.7
ENST00000367781.4
ENST00000367782.4
ENST00000367780.4
ENST00000367779.4
SELE
selectin E
chr3_-_165555200 0.23 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
BCHE
butyrylcholinesterase
chr2_-_99917639 0.22 ENST00000308528.4
LYG1
lysozyme G-like 1
chr3_+_186285192 0.22 ENST00000439351.1
DNAJB11
DnaJ (Hsp40) homolog, subfamily B, member 11
chr3_+_70048881 0.22 ENST00000483525.1
RP11-460N16.1
RP11-460N16.1
chr6_+_27806319 0.22 ENST00000606613.1
ENST00000396980.3
HIST1H2BN
histone cluster 1, H2bn
chr16_+_69796209 0.22 ENST00000359154.2
ENST00000561780.1
ENST00000563659.1
ENST00000448661.1
WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr6_+_64346386 0.22 ENST00000509330.1
PHF3
PHD finger protein 3
chr6_+_26204825 0.22 ENST00000360441.4
HIST1H4E
histone cluster 1, H4e
chr1_+_86046433 0.22 ENST00000451137.2
CYR61
cysteine-rich, angiogenic inducer, 61
chr17_-_33700626 0.21 ENST00000308377.4
ENST00000394566.1
ENST00000589811.1
ENST00000430814.1
ENST00000427966.1
ENST00000588579.1
ENST00000591682.1
ENST00000441608.2
ENST00000592122.1
SLFN11
schlafen family member 11
chr19_-_53238260 0.21 ENST00000453741.2
ENST00000602162.1
ENST00000601643.1
ENST00000596702.1
ENST00000600943.1
ENST00000543227.1
ENST00000540744.1
ZNF611
zinc finger protein 611
chr4_+_169842707 0.21 ENST00000503290.1
PALLD
palladin, cytoskeletal associated protein
chr22_+_25202232 0.21 ENST00000400358.4
ENST00000400359.4
SGSM1
small G protein signaling modulator 1
chr1_+_202830876 0.21 ENST00000456105.2
RP11-480I12.7
RP11-480I12.7
chr17_-_79849438 0.20 ENST00000331204.4
ENST00000505490.2
ALYREF
Aly/REF export factor
chr2_-_182545603 0.20 ENST00000295108.3
NEUROD1
neuronal differentiation 1
chr20_-_43883197 0.20 ENST00000338380.2
SLPI
secretory leukocyte peptidase inhibitor
chr12_+_58013693 0.20 ENST00000320442.4
ENST00000379218.2
SLC26A10
solute carrier family 26, member 10
chr7_-_134143841 0.20 ENST00000285930.4
AKR1B1
aldo-keto reductase family 1, member B1 (aldose reductase)
chr21_-_43786634 0.19 ENST00000291527.2
TFF1
trefoil factor 1
chr17_-_38956205 0.19 ENST00000306658.7
KRT28
keratin 28
chrX_-_48814810 0.19 ENST00000376488.3
ENST00000396743.3
ENST00000156084.4
OTUD5
OTU domain containing 5
chr22_+_39916558 0.19 ENST00000337304.2
ENST00000396680.1
ATF4
activating transcription factor 4
chr1_+_46049706 0.19 ENST00000527470.1
ENST00000525515.1
ENST00000537798.1
ENST00000402363.3
ENST00000528238.1
ENST00000350030.3
ENST00000470768.1
ENST00000372052.4
ENST00000351223.3
NASP
nuclear autoantigenic sperm protein (histone-binding)
chr22_+_19467261 0.19 ENST00000455750.1
ENST00000437685.2
ENST00000263201.1
ENST00000404724.3
CDC45
cell division cycle 45
chr5_-_54988559 0.19 ENST00000502247.1
SLC38A9
solute carrier family 38, member 9
chr6_-_3227877 0.19 ENST00000259818.7
TUBB2B
tubulin, beta 2B class IIb
chr18_+_9102669 0.19 ENST00000497577.2
NDUFV2
NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
chr19_+_8386371 0.19 ENST00000600659.2
RPS28
ribosomal protein S28
chr8_+_1993173 0.19 ENST00000523438.1
MYOM2
myomesin 2
chr11_+_46958248 0.19 ENST00000536126.1
ENST00000278460.7
ENST00000378618.2
ENST00000395460.2
ENST00000378615.3
ENST00000543718.1
C11orf49
chromosome 11 open reading frame 49
chr4_+_119199864 0.18 ENST00000602414.1
ENST00000602520.1
SNHG8
small nucleolar RNA host gene 8 (non-protein coding)
chr13_+_27844464 0.18 ENST00000241463.4
RASL11A
RAS-like, family 11, member A

Network of associatons between targets according to the STRING database.

First level regulatory network of TBP

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.8 3.3 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.4 1.1 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
0.3 1.0 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.3 1.0 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.3 2.9 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.3 1.4 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.3 1.6 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.2 0.5 GO:0090381 negative regulation of mesodermal cell fate specification(GO:0042662) regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012)
0.2 0.5 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.2 0.5 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.2 0.5 GO:2000627 regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.1 0.6 GO:0035425 autocrine signaling(GO:0035425)
0.1 0.4 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.4 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.1 1.7 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 3.1 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.1 0.8 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.1 0.4 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.1 0.7 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 0.8 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.3 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.1 0.2 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.3 GO:1901143 insulin catabolic process(GO:1901143)
0.1 0.4 GO:1902304 positive regulation of potassium ion export(GO:1902304)
0.1 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 2.6 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.1 0.3 GO:2000508 regulation of dendritic cell chemotaxis(GO:2000508) positive regulation of dendritic cell chemotaxis(GO:2000510)
0.1 0.2 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.1 0.8 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.1 0.2 GO:0006059 hexitol metabolic process(GO:0006059)
0.1 1.0 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.2 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 0.5 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.2 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
0.1 0.9 GO:0019441 tryptophan catabolic process to kynurenine(GO:0019441)
0.1 0.3 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 0.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.1 0.6 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.1 0.8 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.2 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.3 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.2 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.2 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.1 GO:0060467 egg activation(GO:0007343) negative regulation of fertilization(GO:0060467)
0.0 0.1 GO:0002215 defense response to nematode(GO:0002215)
0.0 0.4 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.0 0.6 GO:0019532 oxalate transport(GO:0019532)
0.0 1.5 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.2 GO:1902957 negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.0 0.1 GO:0001694 histamine biosynthetic process(GO:0001694)
0.0 0.4 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.5 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.3 GO:2000567 memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568)
0.0 0.2 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.3 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.1 GO:2000852 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.0 0.1 GO:1904666 regulation of ubiquitin protein ligase activity(GO:1904666) positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.0 0.2 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.1 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.0 0.2 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.0 0.1 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.0 3.3 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.3 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.1 GO:2000224 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.0 0.0 GO:0014916 regulation of lung blood pressure(GO:0014916)
0.0 0.1 GO:0018277 protein deamination(GO:0018277)
0.0 0.2 GO:0045943 regulation of transcription from RNA polymerase I promoter(GO:0006356) positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.3 GO:0060591 chondroblast differentiation(GO:0060591)
0.0 0.2 GO:0019236 response to pheromone(GO:0019236)
0.0 0.2 GO:0000255 allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449)
0.0 0.4 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.1 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.0 4.5 GO:0031424 keratinization(GO:0031424)
0.0 0.2 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.7 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.1 GO:0034694 response to prostaglandin(GO:0034694)
0.0 0.7 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.3 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.2 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.5 GO:0061000 negative regulation of dendritic spine development(GO:0061000)
0.0 0.3 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0 0.3 GO:0010616 negative regulation of cardiac muscle adaptation(GO:0010616) lung vasculature development(GO:0060426) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.0 0.1 GO:1904796 regulation of core promoter binding(GO:1904796) positive regulation of core promoter binding(GO:1904798)
0.0 0.2 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.2 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.1 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.2 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.1 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.0 0.1 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.1 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.2 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:1902669 positive regulation of axon guidance(GO:1902669)
0.0 0.3 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.4 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.3 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.2 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.0 0.1 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.2 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.1 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.1 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.0 0.1 GO:0060323 head morphogenesis(GO:0060323) face morphogenesis(GO:0060325)
0.0 2.2 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.5 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.4 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.5 GO:1901687 glutathione derivative metabolic process(GO:1901685) glutathione derivative biosynthetic process(GO:1901687)
0.0 0.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.5 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.0 GO:0042322 positive regulation of growth rate(GO:0040010) negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322) regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768)
0.0 0.2 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.4 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0046813 receptor-mediated virion attachment to host cell(GO:0046813)
0.0 0.0 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.0 0.1 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 0.1 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.0 0.2 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.2 GO:0003334 keratinocyte development(GO:0003334)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.4 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1 2.6 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 0.4 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 3.5 GO:0000786 nucleosome(GO:0000786)
0.1 0.5 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.6 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 3.1 GO:0045095 keratin filament(GO:0045095)
0.0 0.4 GO:0036128 CatSper complex(GO:0036128)
0.0 0.3 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.2 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.1 GO:0097450 astrocyte end-foot(GO:0097450) glial limiting end-foot(GO:0097451)
0.0 0.1 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 3.7 GO:0018995 host(GO:0018995) host cell(GO:0043657)
0.0 0.2 GO:0032584 growth cone membrane(GO:0032584)
0.0 2.4 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.2 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.2 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.5 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.8 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 2.9 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 1.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0097386 glial cell projection(GO:0097386)
0.0 0.3 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.2 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.7 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.0 GO:0070702 inner mucus layer(GO:0070702) outer mucus layer(GO:0070703)
0.0 0.7 GO:0001772 immunological synapse(GO:0001772)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.7 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.3 3.1 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.2 3.1 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 0.8 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.2 0.9 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.2 1.0 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.4 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.1 0.3 GO:0031626 beta-endorphin binding(GO:0031626)
0.1 0.2 GO:0033265 choline binding(GO:0033265)
0.1 0.8 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.8 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.1 0.5 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 3.0 GO:0042056 chemoattractant activity(GO:0042056)
0.1 0.3 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.3 GO:0036033 mediator complex binding(GO:0036033)
0.1 0.4 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.1 0.2 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.5 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.2 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.0 0.4 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.3 GO:0023030 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.0 0.4 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.2 GO:0010853 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.1 GO:0001132 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.0 1.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0047017 geranylgeranyl reductase activity(GO:0045550) prostaglandin-F synthase activity(GO:0047017)
0.0 0.2 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.2 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.2 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 0.1 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.4 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.4 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.3 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.6 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.1 GO:0051400 BH domain binding(GO:0051400)
0.0 2.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.5 GO:0035198 miRNA binding(GO:0035198) RNA stem-loop binding(GO:0035613)
0.0 0.2 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 2.8 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.4 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.2 GO:0032395 MHC class II receptor activity(GO:0032395)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.0 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.0 GO:0016608 growth hormone-releasing hormone activity(GO:0016608) ghrelin receptor binding(GO:0031768)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.5 GO:0070628 proteasome binding(GO:0070628)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 1.0 GO:0019894 kinesin binding(GO:0019894)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 1.4 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 2.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 1.2 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.0 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 2.6 GO:0003735 structural constituent of ribosome(GO:0003735)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 2.0 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.9 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 3.5 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.1 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.6 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.7 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.2 11.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.2 3.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 2.6 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 4.6 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 8.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.0 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.8 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.4 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.5 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.2 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.6 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis