ISMARA results: SREBF1

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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SREBF1_TFE3

Z-value: 1.68

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Transcription factors associated with SREBF1_TFE3

Gene Symbol	Gene ID	Gene Info
SREBF1 Ensembl NCBI GeneCards UniProt	ENSG00000072310.12	sterol regulatory element binding transcription factor 1
TFE3 Ensembl NCBI GeneCards UniProt	ENSG00000068323.12	transcription factor binding to IGHM enhancer 3

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
SREBF1	hg19_v2_chr17_-_17740325_17740349	0.96	2.1e-03	Click!
TFE3	hg19_v2_chrX_-_48901012_48901050	0.86	2.6e-02	Click!

Activity profile of SREBF1_TFE3 motif

Sorted Z-values of SREBF1_TFE3 motif

Top targets:

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr12_-_58145889 Show fit	11.81	ENST00000547853.1	CDK4 Ensembl NCBI GeneCards UniProt Show fit	cyclin-dependent kinase 4
chr20_-_44519839 Show fit	2.76	ENST00000372518.4	NEURL2 Ensembl NCBI GeneCards UniProt Show fit	neuralized E3 ubiquitin protein ligase 2
chr17_-_7137857 Show fit	2.67	ENST00000005340.5	DVL2 Ensembl NCBI GeneCards UniProt Show fit	dishevelled segment polarity protein 2
chr17_-_7137582 Show fit	2.41	ENST00000575756.1 ENST00000575458.1	DVL2 Ensembl NCBI GeneCards UniProt Show fit	dishevelled segment polarity protein 2
chr20_+_44519948 Show fit	1.94	ENST00000354880.5 ENST00000191018.5	CTSA Ensembl NCBI GeneCards UniProt Show fit	cathepsin A
chr16_+_2570340 Show fit	1.92	ENST00000568263.1 ENST00000293971.6 ENST00000302956.4 ENST00000413459.3 ENST00000566706.1 ENST00000569879.1	AMDHD2 Ensembl NCBI GeneCards UniProt Show fit	amidohydrolase domain containing 2
chr11_+_67159416 Show fit	1.77	ENST00000307980.2 ENST00000544620.1	RAD9A Ensembl NCBI GeneCards UniProt Show fit	RAD9 homolog A (S. pombe)
chr19_-_36545649 Show fit	1.72	ENST00000292894.1	THAP8 Ensembl NCBI GeneCards UniProt Show fit	THAP domain containing 8
chr16_+_28986134 Show fit	1.72	ENST00000352260.7	SPNS1 Ensembl NCBI GeneCards UniProt Show fit	spinster homolog 1 (Drosophila)
chr19_+_7587555 Show fit	1.64	ENST00000601003.1	MCOLN1 Ensembl NCBI GeneCards UniProt Show fit	mucolipin 1
chr19_+_49458107 Show fit	1.59	ENST00000539787.1 ENST00000345358.7 ENST00000391871.3 ENST00000415969.2 ENST00000354470.3 ENST00000506183.1 ENST00000293288.8	BAX Ensembl NCBI GeneCards UniProt Show fit	BCL2-associated X protein
chr20_+_44520009 Show fit	1.53	ENST00000607482.1 ENST00000372459.2	CTSA Ensembl NCBI GeneCards UniProt Show fit	cathepsin A
chr16_-_67514982 Show fit	1.53	ENST00000565835.1 ENST00000540149.1 ENST00000290949.3	ATP6V0D1 Ensembl NCBI GeneCards UniProt Show fit	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr16_+_5083950 Show fit	1.50	ENST00000588623.1	ALG1 Ensembl NCBI GeneCards UniProt Show fit	ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr19_+_10764937 Show fit	1.45	ENST00000449870.1 ENST00000318511.3 ENST00000420083.1	ILF3 Ensembl NCBI GeneCards UniProt Show fit	interleukin enhancer binding factor 3, 90kDa
chrX_-_102565932 Show fit	1.44	ENST00000372674.1 ENST00000372677.3	BEX2 Ensembl NCBI GeneCards UniProt Show fit	brain expressed X-linked 2
chr11_-_1785139 Show fit	1.42	ENST00000236671.2	CTSD Ensembl NCBI GeneCards UniProt Show fit	cathepsin D
chr13_+_113951607 Show fit	1.42	ENST00000397181.3	LAMP1 Ensembl NCBI GeneCards UniProt Show fit	lysosomal-associated membrane protein 1
chr2_+_220042933 Show fit	1.41	ENST00000430297.2	FAM134A Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 134, member A
chr1_-_21995794 Show fit	1.41	ENST00000542643.2 ENST00000374765.4 ENST00000317967.7	RAP1GAP Ensembl NCBI GeneCards UniProt Show fit	RAP1 GTPase activating protein
chr16_+_28986085 Show fit	1.40	ENST00000565975.1 ENST00000311008.11 ENST00000323081.8 ENST00000334536.8	SPNS1 Ensembl NCBI GeneCards UniProt Show fit	spinster homolog 1 (Drosophila)
chr7_+_4815238 Show fit	1.40	ENST00000348624.4 ENST00000401897.1	AP5Z1 Ensembl NCBI GeneCards UniProt Show fit	adaptor-related protein complex 5, zeta 1 subunit
chr12_-_58146128 Show fit	1.37	ENST00000551800.1 ENST00000549606.1 ENST00000257904.6	CDK4 Ensembl NCBI GeneCards UniProt Show fit	cyclin-dependent kinase 4
chr12_-_58146048 Show fit	1.35	ENST00000547281.1 ENST00000546489.1 ENST00000552388.1 ENST00000540325.1 ENST00000312990.6	CDK4 Ensembl NCBI GeneCards UniProt Show fit	cyclin-dependent kinase 4
chr16_-_28503080 Show fit	1.34	ENST00000565316.1 ENST00000565778.1 ENST00000357857.9 ENST00000568558.1 ENST00000357806.7	CLN3 Ensembl NCBI GeneCards UniProt Show fit	ceroid-lipofuscinosis, neuronal 3
chr17_+_3539998 Show fit	1.34	ENST00000452111.1 ENST00000574776.1 ENST00000441220.2 ENST00000414524.2	CTNS Ensembl NCBI GeneCards UniProt Show fit	cystinosin, lysosomal cystine transporter
chr16_-_5083917 Show fit	1.33	ENST00000312251.3 ENST00000381955.3	NAGPA Ensembl NCBI GeneCards UniProt Show fit	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chr18_+_20715416 Show fit	1.32	ENST00000580153.1	CABLES1 Ensembl NCBI GeneCards UniProt Show fit	Cdk5 and Abl enzyme substrate 1
chr14_-_68283291 Show fit	1.31	ENST00000555452.1 ENST00000347230.4	ZFYVE26 Ensembl NCBI GeneCards UniProt Show fit	zinc finger, FYVE domain containing 26
chr17_+_73975292 Show fit	1.27	ENST00000397640.1 ENST00000416485.1 ENST00000588202.1 ENST00000590676.1 ENST00000586891.1	TEN1 Ensembl NCBI GeneCards UniProt Show fit	TEN1 CST complex subunit
chr5_+_150827143 Show fit	1.23	ENST00000243389.3 ENST00000517945.1 ENST00000521925.1	SLC36A1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 36 (proton/amino acid symporter), member 1
chr1_+_44440575 Show fit	1.23	ENST00000532642.1 ENST00000236067.4 ENST00000471859.2	ATP6V0B Ensembl NCBI GeneCards UniProt Show fit	ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr19_+_41256764 Show fit	1.23	ENST00000243563.3 ENST00000601253.1 ENST00000597353.1 ENST00000599362.1	SNRPA Ensembl NCBI GeneCards UniProt Show fit	small nuclear ribonucleoprotein polypeptide A
chr3_+_127317705 Show fit	1.22	ENST00000480910.1	MCM2 Ensembl NCBI GeneCards UniProt Show fit	minichromosome maintenance complex component 2
chr16_-_28503357 Show fit	1.21	ENST00000333496.9 ENST00000561505.1 ENST00000567963.1 ENST00000354630.5 ENST00000355477.5 ENST00000357076.5 ENST00000565688.1 ENST00000359984.7	CLN3 Ensembl NCBI GeneCards UniProt Show fit	ceroid-lipofuscinosis, neuronal 3
chr17_+_3540043 Show fit	1.20	ENST00000574218.1	CTNS Ensembl NCBI GeneCards UniProt Show fit	cystinosin, lysosomal cystine transporter
chr16_-_1525016 Show fit	1.19	ENST00000262318.8 ENST00000448525.1	CLCN7 Ensembl NCBI GeneCards UniProt Show fit	chloride channel, voltage-sensitive 7
chr17_+_3539744 Show fit	1.18	ENST00000046640.3 ENST00000381870.3	CTNS Ensembl NCBI GeneCards UniProt Show fit	cystinosin, lysosomal cystine transporter
chr3_-_126076264 Show fit	1.16	ENST00000296233.3	KLF15 Ensembl NCBI GeneCards UniProt Show fit	Kruppel-like factor 15
chr16_+_2570431 Show fit	1.16	ENST00000563556.1	AMDHD2 Ensembl NCBI GeneCards UniProt Show fit	amidohydrolase domain containing 2
chr9_+_131084815 Show fit	1.13	ENST00000300452.3 ENST00000609948.1	COQ4 Ensembl NCBI GeneCards UniProt Show fit	coenzyme Q4
chr17_+_1627834 Show fit	1.12	ENST00000419248.1 ENST00000418841.1	WDR81 Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 81
chr16_-_58718638 Show fit	1.12	ENST00000562397.1 ENST00000564010.1 ENST00000570214.1 ENST00000563196.1	SLC38A7 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 38, member 7
chr11_-_36310958 Show fit	1.10	ENST00000532705.1 ENST00000263401.5 ENST00000452374.2	COMMD9 Ensembl NCBI GeneCards UniProt Show fit	COMM domain containing 9
chr19_+_10765003 Show fit	1.10	ENST00000407004.3 ENST00000589998.1 ENST00000589600.1	ILF3 Ensembl NCBI GeneCards UniProt Show fit	interleukin enhancer binding factor 3, 90kDa
chr16_-_28503327 Show fit	1.10	ENST00000535392.1 ENST00000395653.4	CLN3 Ensembl NCBI GeneCards UniProt Show fit	ceroid-lipofuscinosis, neuronal 3
chr13_+_113951532 Show fit	1.09	ENST00000332556.4	LAMP1 Ensembl NCBI GeneCards UniProt Show fit	lysosomal-associated membrane protein 1
chr14_-_20929624 Show fit	1.09	ENST00000398020.4 ENST00000250489.4	TMEM55B Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 55B
chr17_-_6915616 Show fit	1.09	ENST00000575889.1	AC027763.2 Ensembl NCBI GeneCards UniProt Show fit	Uncharacterized protein
chr6_-_33385655 Show fit	1.08	ENST00000440279.3 ENST00000607266.1	CUTA Ensembl NCBI GeneCards UniProt Show fit	cutA divalent cation tolerance homolog (E. coli)
chr1_+_3816936 Show fit	1.06	ENST00000413332.1 ENST00000442673.1 ENST00000439488.1	RP13-15E13.1 Ensembl NCBI GeneCards UniProt Show fit	long intergenic non-protein coding RNA 1134
chr7_+_916183 Show fit	1.06	ENST00000265857.3	GET4 Ensembl NCBI GeneCards UniProt Show fit	golgi to ER traffic protein 4 homolog (S. cerevisiae)
chr6_+_42018251 Show fit	1.05	ENST00000372978.3 ENST00000494547.1 ENST00000456846.2 ENST00000372982.4 ENST00000472818.1 ENST00000372977.3	TAF8 Ensembl NCBI GeneCards UniProt Show fit	TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
chr19_-_36545128 Show fit	1.02	ENST00000538849.1	THAP8 Ensembl NCBI GeneCards UniProt Show fit	THAP domain containing 8
chr16_-_5083589 Show fit	1.02	ENST00000563578.1 ENST00000562346.2	NAGPA Ensembl NCBI GeneCards UniProt Show fit	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
chrX_-_102565858 Show fit	1.00	ENST00000449185.1 ENST00000536889.1	BEX2 Ensembl NCBI GeneCards UniProt Show fit	brain expressed X-linked 2
chr16_+_28985542 Show fit	0.99	ENST00000567771.1 ENST00000568388.1	SPNS1 Ensembl NCBI GeneCards UniProt Show fit	spinster homolog 1 (Drosophila)
chr2_-_220042825 Show fit	0.99	ENST00000409789.1	CNPPD1 Ensembl NCBI GeneCards UniProt Show fit	cyclin Pas1/PHO80 domain containing 1
chr1_+_11866270 Show fit	0.98	ENST00000376497.3 ENST00000376487.3 ENST00000376496.3	CLCN6 Ensembl NCBI GeneCards UniProt Show fit	chloride channel, voltage-sensitive 6
chr17_-_48450534 Show fit	0.98	ENST00000503633.1 ENST00000442592.3 ENST00000225969.4	MRPL27 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein L27
chr11_-_1606513 Show fit	0.97	ENST00000382171.2	KRTAP5-1 Ensembl NCBI GeneCards UniProt Show fit	keratin associated protein 5-1
chr22_-_36903069 Show fit	0.97	ENST00000216187.6 ENST00000423980.1	FOXRED2 Ensembl NCBI GeneCards UniProt Show fit	FAD-dependent oxidoreductase domain containing 2
chr16_-_58718611 Show fit	0.97	ENST00000564100.1 ENST00000570101.1	SLC38A7 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 38, member 7
chr1_-_27682962 Show fit	0.97	ENST00000486046.1	MAP3K6 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase kinase 6
chr6_-_33385823 Show fit	0.96	ENST00000494751.1 ENST00000374496.3	CUTA Ensembl NCBI GeneCards UniProt Show fit	cutA divalent cation tolerance homolog (E. coli)
chr19_+_12848299 Show fit	0.96	ENST00000357332.3	ASNA1 Ensembl NCBI GeneCards UniProt Show fit	arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
chr17_-_73851285 Show fit	0.96	ENST00000589642.1 ENST00000593002.1 ENST00000590221.1 ENST00000344296.4 ENST00000587374.1 ENST00000585462.1 ENST00000433525.2 ENST00000254806.3	WBP2 Ensembl NCBI GeneCards UniProt Show fit	WW domain binding protein 2
chr20_-_36156125 Show fit	0.95	ENST00000397135.1 ENST00000397137.1	BLCAP Ensembl NCBI GeneCards UniProt Show fit	bladder cancer associated protein
chr9_-_131709858 Show fit	0.94	ENST00000372586.3	DOLK Ensembl NCBI GeneCards UniProt Show fit	dolichol kinase
chr12_-_114404111 Show fit	0.94	ENST00000545145.2 ENST00000392561.3 ENST00000261741.5	RBM19 Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 19
chr5_+_149340339 Show fit	0.92	ENST00000433184.1	SLC26A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 26 (anion exchanger), member 2
chr3_+_51428704 Show fit	0.92	ENST00000323686.4	RBM15B Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 15B
chr3_+_50654821 Show fit	0.92	ENST00000457064.1	MAPKAPK3 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase-activated protein kinase 3
chr9_-_140335789 Show fit	0.92	ENST00000344119.2 ENST00000371506.2	ENTPD8 Ensembl NCBI GeneCards UniProt Show fit	ectonucleoside triphosphate diphosphohydrolase 8
chr17_+_79935418 Show fit	0.90	ENST00000306729.7 ENST00000306739.4	ASPSCR1 Ensembl NCBI GeneCards UniProt Show fit	alveolar soft part sarcoma chromosome region, candidate 1
chr19_-_40854281 Show fit	0.89	ENST00000392035.2	C19orf47 Ensembl NCBI GeneCards UniProt Show fit	chromosome 19 open reading frame 47
chr2_-_47572105 Show fit	0.88	ENST00000419035.1 ENST00000448713.1 ENST00000450550.1 ENST00000413185.2	AC073283.4 Ensembl NCBI GeneCards UniProt Show fit	AC073283.4
chr19_-_40854417 Show fit	0.88	ENST00000582006.1 ENST00000582783.1	C19orf47 Ensembl NCBI GeneCards UniProt Show fit	chromosome 19 open reading frame 47
chr1_-_156265438 Show fit	0.87	ENST00000362007.1	C1orf85 Ensembl NCBI GeneCards UniProt Show fit	chromosome 1 open reading frame 85
chr6_+_160390102 Show fit	0.86	ENST00000356956.1	IGF2R Ensembl NCBI GeneCards UniProt Show fit	insulin-like growth factor 2 receptor
chr16_+_69796209 Show fit	0.84	ENST00000359154.2 ENST00000561780.1 ENST00000563659.1 ENST00000448661.1	WWP2 Ensembl NCBI GeneCards UniProt Show fit	WW domain containing E3 ubiquitin protein ligase 2
chr19_-_3985455 Show fit	0.84	ENST00000309311.6	EEF2 Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation elongation factor 2
chr7_+_100271446 Show fit	0.83	ENST00000419828.1 ENST00000427895.1	GNB2 Ensembl NCBI GeneCards UniProt Show fit	guanine nucleotide binding protein (G protein), beta polypeptide 2
chr1_+_11866207 Show fit	0.83	ENST00000312413.6 ENST00000346436.6	CLCN6 Ensembl NCBI GeneCards UniProt Show fit	chloride channel, voltage-sensitive 6
chr12_+_6833323 Show fit	0.83	ENST00000544725.1	COPS7A Ensembl NCBI GeneCards UniProt Show fit	COP9 signalosome subunit 7A
chr9_+_131709966 Show fit	0.81	ENST00000372577.2	NUP188 Ensembl NCBI GeneCards UniProt Show fit	nucleoporin 188kDa
chr12_-_63328817 Show fit	0.81	ENST00000228705.6	PPM1H Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr19_-_13227514 Show fit	0.81	ENST00000587487.1 ENST00000592814.1	TRMT1 Ensembl NCBI GeneCards UniProt Show fit	tRNA methyltransferase 1 homolog (S. cerevisiae)
chr9_-_90589586 Show fit	0.81	ENST00000325303.8 ENST00000375883.3	CDK20 Ensembl NCBI GeneCards UniProt Show fit	cyclin-dependent kinase 20
chr11_+_118938485 Show fit	0.80	ENST00000300793.6	VPS11 Ensembl NCBI GeneCards UniProt Show fit	vacuolar protein sorting 11 homolog (S. cerevisiae)
chr5_-_175964366 Show fit	0.80	ENST00000274811.4	RNF44 Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 44
chr9_+_131799213 Show fit	0.80	ENST00000358369.4 ENST00000406926.2 ENST00000277475.5 ENST00000450073.1	FAM73B Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 73, member B
chr14_-_20923195 Show fit	0.80	ENST00000206542.4	OSGEP Ensembl NCBI GeneCards UniProt Show fit	O-sialoglycoprotein endopeptidase
chr14_-_81687575 Show fit	0.79	ENST00000434192.2	GTF2A1 Ensembl NCBI GeneCards UniProt Show fit	general transcription factor IIA, 1, 19/37kDa
chr1_-_27226928 Show fit	0.79	ENST00000361720.5	GPATCH3 Ensembl NCBI GeneCards UniProt Show fit	G patch domain containing 3
chr19_-_10764509 Show fit	0.79	ENST00000591501.1	ILF3-AS1 Ensembl NCBI GeneCards UniProt Show fit	ILF3 antisense RNA 1 (head to head)
chr22_+_31003133 Show fit	0.79	ENST00000405742.3	TCN2 Ensembl NCBI GeneCards UniProt Show fit	transcobalamin II
chr17_+_78075498 Show fit	0.79	ENST00000302262.3	GAA Ensembl NCBI GeneCards UniProt Show fit	glucosidase, alpha; acid
chr17_+_42422662 Show fit	0.79	ENST00000593167.1 ENST00000585512.1 ENST00000591740.1 ENST00000592783.1 ENST00000587387.1 ENST00000588237.1 ENST00000589265.1	GRN Ensembl NCBI GeneCards UniProt Show fit	granulin
chr17_+_42422637 Show fit	0.78	ENST00000053867.3 ENST00000588143.1	GRN Ensembl NCBI GeneCards UniProt Show fit	granulin
chr19_+_797392 Show fit	0.77	ENST00000350092.4 ENST00000349038.4 ENST00000586481.1 ENST00000585535.1	PTBP1 Ensembl NCBI GeneCards UniProt Show fit	polypyrimidine tract binding protein 1
chr11_+_62538775 Show fit	0.77	ENST00000294168.3 ENST00000526261.1	TAF6L Ensembl NCBI GeneCards UniProt Show fit	TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
chr7_+_100271355 Show fit	0.76	ENST00000436220.1 ENST00000424361.1	GNB2 Ensembl NCBI GeneCards UniProt Show fit	guanine nucleotide binding protein (G protein), beta polypeptide 2
chr19_+_6464243 Show fit	0.76	ENST00000600229.1 ENST00000356762.3	CRB3 Ensembl NCBI GeneCards UniProt Show fit	crumbs homolog 3 (Drosophila)
chr16_+_1401924 Show fit	0.76	ENST00000204679.4 ENST00000529110.1	GNPTG Ensembl NCBI GeneCards UniProt Show fit	N-acetylglucosamine-1-phosphate transferase, gamma subunit
chr6_-_33385870 Show fit	0.76	ENST00000488034.1	CUTA Ensembl NCBI GeneCards UniProt Show fit	cutA divalent cation tolerance homolog (E. coli)
chr7_+_102073966 Show fit	0.74	ENST00000495936.1 ENST00000356387.2 ENST00000478730.2 ENST00000468241.1 ENST00000403646.3	ORAI2 Ensembl NCBI GeneCards UniProt Show fit	ORAI calcium release-activated calcium modulator 2
chr12_+_117176113 Show fit	0.74	ENST00000319176.7	RNFT2 Ensembl NCBI GeneCards UniProt Show fit	ring finger protein, transmembrane 2
chrX_+_118108571 Show fit	0.74	ENST00000304778.7	LONRF3 Ensembl NCBI GeneCards UniProt Show fit	LON peptidase N-terminal domain and ring finger 3
chr17_+_42422629 Show fit	0.74	ENST00000589536.1 ENST00000587109.1 ENST00000587518.1	GRN Ensembl NCBI GeneCards UniProt Show fit	granulin
chr1_+_221051699 Show fit	0.74	ENST00000366903.6	HLX Ensembl NCBI GeneCards UniProt Show fit	H2.0-like homeobox
chr1_-_183538319 Show fit	0.73	ENST00000420553.1 ENST00000419402.1	NCF2 Ensembl NCBI GeneCards UniProt Show fit	neutrophil cytosolic factor 2
chr11_-_116968987 Show fit	0.73	ENST00000434315.2 ENST00000292055.4 ENST00000375288.1 ENST00000542607.1 ENST00000445177.1 ENST00000375300.1 ENST00000446921.2	SIK3 Ensembl NCBI GeneCards UniProt Show fit	SIK family kinase 3
chr17_+_79031415 Show fit	0.73	ENST00000572073.1 ENST00000573677.1	BAIAP2 Ensembl NCBI GeneCards UniProt Show fit	BAI1-associated protein 2
chr19_+_7587491 Show fit	0.73	ENST00000264079.6	MCOLN1 Ensembl NCBI GeneCards UniProt Show fit	mucolipin 1
chr22_+_31002990 Show fit	0.72	ENST00000423350.1	TCN2 Ensembl NCBI GeneCards UniProt Show fit	transcobalamin II
chr9_-_90589402 Show fit	0.72	ENST00000375871.4 ENST00000605159.1 ENST00000336654.5	CDK20 Ensembl NCBI GeneCards UniProt Show fit	cyclin-dependent kinase 20
chr7_+_99070464 Show fit	0.71	ENST00000331410.5 ENST00000483089.1 ENST00000448667.1 ENST00000493485.1	ZNF789 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 789
chr15_-_40213080 Show fit	0.71	ENST00000561100.1	GPR176 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 176
chr1_+_45477901 Show fit	0.71	ENST00000434478.1	UROD Ensembl NCBI GeneCards UniProt Show fit	uroporphyrinogen decarboxylase
chr22_-_39636914 Show fit	0.71	ENST00000381551.4	PDGFB Ensembl NCBI GeneCards UniProt Show fit	platelet-derived growth factor beta polypeptide
chr3_-_53080672 Show fit	0.70	ENST00000483069.1	SFMBT1 Ensembl NCBI GeneCards UniProt Show fit	Scm-like with four mbt domains 1
chr15_-_72668805 Show fit	0.70	ENST00000268097.5	HEXA Ensembl NCBI GeneCards UniProt Show fit	hexosaminidase A (alpha polypeptide)
chr2_-_26101314 Show fit	0.69	ENST00000336112.4 ENST00000272341.4	ASXL2 Ensembl NCBI GeneCards UniProt Show fit	additional sex combs like 2 (Drosophila)
chr22_-_39268308 Show fit	0.69	ENST00000407418.3	CBX6 Ensembl NCBI GeneCards UniProt Show fit	chromobox homolog 6
chr3_-_127317047 Show fit	0.68	ENST00000462228.1 ENST00000490643.1	TPRA1 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein, adipocyte asscociated 1
chr19_-_15236470 Show fit	0.68	ENST00000533747.1 ENST00000598709.1 ENST00000534378.1	ILVBL Ensembl NCBI GeneCards UniProt Show fit	ilvB (bacterial acetolactate synthase)-like
chr1_+_110881945 Show fit	0.68	ENST00000602849.1 ENST00000487146.2	RBM15 Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 15
chr17_-_3539558 Show fit	0.68	ENST00000225519.3	SHPK Ensembl NCBI GeneCards UniProt Show fit	sedoheptulokinase
chr1_+_179051160 Show fit	0.67	ENST00000367625.4 ENST00000352445.6	TOR3A Ensembl NCBI GeneCards UniProt Show fit	torsin family 3, member A
chrX_+_10126488 Show fit	0.67	ENST00000380829.1 ENST00000421085.2 ENST00000454850.1	CLCN4 Ensembl NCBI GeneCards UniProt Show fit	chloride channel, voltage-sensitive 4
chr17_+_78075361 Show fit	0.67	ENST00000577106.1 ENST00000390015.3	GAA Ensembl NCBI GeneCards UniProt Show fit	glucosidase, alpha; acid
chr20_-_2821271 Show fit	0.67	ENST00000448755.1 ENST00000360652.2	PCED1A Ensembl NCBI GeneCards UniProt Show fit	PC-esterase domain containing 1A
chr22_+_40573921 Show fit	0.67	ENST00000454349.2 ENST00000335727.9	TNRC6B Ensembl NCBI GeneCards UniProt Show fit	trinucleotide repeat containing 6B
chr16_+_5121814 Show fit	0.66	ENST00000262374.5 ENST00000586840.1	ALG1 Ensembl NCBI GeneCards UniProt Show fit	ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
chr9_-_131084497 Show fit	0.66	ENST00000546104.1	TRUB2 Ensembl NCBI GeneCards UniProt Show fit	TruB pseudouridine (psi) synthase family member 2
chr17_+_18218587 Show fit	0.66	ENST00000406438.3	SMCR8 Ensembl NCBI GeneCards UniProt Show fit	Smith-Magenis syndrome chromosome region, candidate 8
chr1_+_22778337 Show fit	0.66	ENST00000404138.1 ENST00000400239.2 ENST00000375647.4 ENST00000374651.4	ZBTB40 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 40
chr19_-_13227463 Show fit	0.66	ENST00000437766.1 ENST00000221504.8	TRMT1 Ensembl NCBI GeneCards UniProt Show fit	tRNA methyltransferase 1 homolog (S. cerevisiae)
chr1_-_11866034 Show fit	0.66	ENST00000376590.3	MTHFR Ensembl NCBI GeneCards UniProt Show fit	methylenetetrahydrofolate reductase (NAD(P)H)
chr10_-_105437909 Show fit	0.66	ENST00000540321.1	SH3PXD2A Ensembl NCBI GeneCards UniProt Show fit	SH3 and PX domains 2A
chr5_+_176730769 Show fit	0.65	ENST00000303204.4 ENST00000503216.1	PRELID1 Ensembl NCBI GeneCards UniProt Show fit	PRELI domain containing 1
chr6_-_44225231 Show fit	0.64	ENST00000538577.1 ENST00000537814.1 ENST00000393810.1 ENST00000393812.3	SLC35B2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
chr17_-_77967433 Show fit	0.64	ENST00000571872.1	TBC1D16 Ensembl NCBI GeneCards UniProt Show fit	TBC1 domain family, member 16
chr17_-_48450265 Show fit	0.64	ENST00000507088.1	MRPL27 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein L27
chr7_-_150777920 Show fit	0.64	ENST00000353841.2 ENST00000297532.6	FASTK Ensembl NCBI GeneCards UniProt Show fit	Fas-activated serine/threonine kinase
chr19_+_6464502 Show fit	0.63	ENST00000308243.7	CRB3 Ensembl NCBI GeneCards UniProt Show fit	crumbs homolog 3 (Drosophila)
chr5_-_176730733 Show fit	0.63	ENST00000504395.1	RAB24 Ensembl NCBI GeneCards UniProt Show fit	RAB24, member RAS oncogene family
chr12_+_54426637 Show fit	0.62	ENST00000312492.2	HOXC5 Ensembl NCBI GeneCards UniProt Show fit	homeobox C5
chr9_-_134585221 Show fit	0.62	ENST00000372190.3 ENST00000427994.1	RAPGEF1 Ensembl NCBI GeneCards UniProt Show fit	Rap guanine nucleotide exchange factor (GEF) 1
chr3_-_142720267 Show fit	0.62	ENST00000597953.1	RP11-91G21.1 Ensembl NCBI GeneCards UniProt Show fit	RP11-91G21.1
chr16_+_57220049 Show fit	0.62	ENST00000562439.1	RSPRY1 Ensembl NCBI GeneCards UniProt Show fit	ring finger and SPRY domain containing 1
chr20_-_2821756 Show fit	0.62	ENST00000356872.3 ENST00000439542.1	PCED1A Ensembl NCBI GeneCards UniProt Show fit	PC-esterase domain containing 1A
chr16_-_70323422 Show fit	0.61	ENST00000261772.8	AARS Ensembl NCBI GeneCards UniProt Show fit	alanyl-tRNA synthetase
chr16_-_4588469 Show fit	0.60	ENST00000588381.1 ENST00000563332.2	CDIP1 Ensembl NCBI GeneCards UniProt Show fit	cell death-inducing p53 target 1
chr7_-_150777949 Show fit	0.60	ENST00000482571.1	FASTK Ensembl NCBI GeneCards UniProt Show fit	Fas-activated serine/threonine kinase
chr15_-_72668185 Show fit	0.60	ENST00000457859.2 ENST00000566304.1 ENST00000567159.1 ENST00000429918.2	HEXA Ensembl NCBI GeneCards UniProt Show fit	hexosaminidase A (alpha polypeptide)
chr22_-_20850128 Show fit	0.60	ENST00000328879.4	KLHL22 Ensembl NCBI GeneCards UniProt Show fit	kelch-like family member 22
chr16_-_2097787 Show fit	0.60	ENST00000566380.1 ENST00000219066.1	NTHL1 Ensembl NCBI GeneCards UniProt Show fit	nth endonuclease III-like 1 (E. coli)
chr19_+_38880252 Show fit	0.60	ENST00000586301.1	SPRED3 Ensembl NCBI GeneCards UniProt Show fit	sprouty-related, EVH1 domain containing 3
chr12_-_122751002 Show fit	0.60	ENST00000267199.4	VPS33A Ensembl NCBI GeneCards UniProt Show fit	vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr17_+_78075324 Show fit	0.60	ENST00000570803.1	GAA Ensembl NCBI GeneCards UniProt Show fit	glucosidase, alpha; acid
chr9_+_6716478 Show fit	0.60	ENST00000452643.1	RP11-390F4.3 Ensembl NCBI GeneCards UniProt Show fit	RP11-390F4.3
chr2_-_121624973 Show fit	0.60	ENST00000603720.1	RP11-297J22.1 Ensembl NCBI GeneCards UniProt Show fit	RP11-297J22.1
chrX_+_53123314 Show fit	0.60	ENST00000605526.1 ENST00000604062.1 ENST00000604369.1 ENST00000366185.2 ENST00000604849.1	RP11-258C19.5 Ensembl NCBI GeneCards UniProt Show fit	long intergenic non-protein coding RNA 1155
chr2_+_238499812 Show fit	0.59	ENST00000452801.1	AC104667.3 Ensembl NCBI GeneCards UniProt Show fit	AC104667.3
chr7_+_100464760 Show fit	0.59	ENST00000200457.4	TRIP6 Ensembl NCBI GeneCards UniProt Show fit	thyroid hormone receptor interactor 6
chr5_-_14871866 Show fit	0.58	ENST00000284268.6	ANKH Ensembl NCBI GeneCards UniProt Show fit	ANKH inorganic pyrophosphate transport regulator
chr10_+_51827648 Show fit	0.58	ENST00000351071.6 ENST00000314664.7 ENST00000282633.5	FAM21A Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 21, member A
chr19_+_797443 Show fit	0.58	ENST00000394601.4 ENST00000589575.1	PTBP1 Ensembl NCBI GeneCards UniProt Show fit	polypyrimidine tract binding protein 1
chr22_-_39268192 Show fit	0.58	ENST00000216083.6	CBX6 Ensembl NCBI GeneCards UniProt Show fit	chromobox homolog 6
chr6_+_42018614 Show fit	0.57	ENST00000465926.1 ENST00000482432.1	TAF8 Ensembl NCBI GeneCards UniProt Show fit	TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa
chr19_-_48613987 Show fit	0.57	ENST00000596138.1	PLA2G4C Ensembl NCBI GeneCards UniProt Show fit	phospholipase A2, group IVC (cytosolic, calcium-independent)
chr19_-_13227534 Show fit	0.57	ENST00000588229.1 ENST00000357720.4	TRMT1 Ensembl NCBI GeneCards UniProt Show fit	tRNA methyltransferase 1 homolog (S. cerevisiae)
chr11_+_65479462 Show fit	0.57	ENST00000377046.3 ENST00000352980.4 ENST00000341318.4	KAT5 Ensembl NCBI GeneCards UniProt Show fit	K(lysine) acetyltransferase 5
chr17_-_8301132 Show fit	0.57	ENST00000399398.2	RNF222 Ensembl NCBI GeneCards UniProt Show fit	ring finger protein 222
chr1_+_45477819 Show fit	0.57	ENST00000246337.4	UROD Ensembl NCBI GeneCards UniProt Show fit	uroporphyrinogen decarboxylase
chr12_+_56109810 Show fit	0.57	ENST00000550412.1 ENST00000257899.2 ENST00000548925.1 ENST00000549147.1	RP11-644F5.10 Ensembl NCBI GeneCards UniProt Show fit BLOC1S1 Ensembl NCBI GeneCards UniProt Show fit	Uncharacterized protein biogenesis of lysosomal organelles complex-1, subunit 1
chr18_-_3247084 Show fit	0.57	ENST00000609924.1	RP13-270P17.3 Ensembl NCBI GeneCards UniProt Show fit	RP13-270P17.3
chr19_+_14544099 Show fit	0.56	ENST00000242783.6 ENST00000586557.1 ENST00000590097.1	PKN1 Ensembl NCBI GeneCards UniProt Show fit	protein kinase N1
chr22_-_38577782 Show fit	0.56	ENST00000430886.1 ENST00000332509.3 ENST00000447598.2 ENST00000435484.1 ENST00000402064.1 ENST00000436218.1	PLA2G6 Ensembl NCBI GeneCards UniProt Show fit	phospholipase A2, group VI (cytosolic, calcium-independent)
chr7_+_116593536 Show fit	0.56	ENST00000417919.1	ST7 Ensembl NCBI GeneCards UniProt Show fit	suppression of tumorigenicity 7
chr16_-_4588822 Show fit	0.56	ENST00000564828.1	CDIP1 Ensembl NCBI GeneCards UniProt Show fit	cell death-inducing p53 target 1
chr5_-_38557561 Show fit	0.56	ENST00000511561.1	LIFR Ensembl NCBI GeneCards UniProt Show fit	leukemia inhibitory factor receptor alpha
chr18_-_33047039 Show fit	0.56	ENST00000591141.1 ENST00000586741.1	RP11-322E11.5 Ensembl NCBI GeneCards UniProt Show fit	RP11-322E11.5
chr13_+_49794474 Show fit	0.55	ENST00000218721.1 ENST00000398307.1	MLNR Ensembl NCBI GeneCards UniProt Show fit	motilin receptor
chr17_-_7218631 Show fit	0.55	ENST00000577040.2 ENST00000389167.5 ENST00000391950.3	GPS2 Ensembl NCBI GeneCards UniProt Show fit	G protein pathway suppressor 2
chr17_+_79935464 Show fit	0.55	ENST00000581647.1 ENST00000580534.1 ENST00000579684.1	ASPSCR1 Ensembl NCBI GeneCards UniProt Show fit	alveolar soft part sarcoma chromosome region, candidate 1
chr19_+_36545781 Show fit	0.55	ENST00000388999.3	WDR62 Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 62
chr22_+_35695793 Show fit	0.55	ENST00000456128.1 ENST00000449058.2 ENST00000411850.1 ENST00000425375.1 ENST00000436462.2 ENST00000382034.5	TOM1 Ensembl NCBI GeneCards UniProt Show fit	target of myb1 (chicken)
chr22_+_31003190 Show fit	0.55	ENST00000407817.3	TCN2 Ensembl NCBI GeneCards UniProt Show fit	transcobalamin II
chr6_-_31830655 Show fit	0.55	ENST00000375631.4	NEU1 Ensembl NCBI GeneCards UniProt Show fit	sialidase 1 (lysosomal sialidase)
chr1_-_204329013 Show fit	0.54	ENST00000272203.3 ENST00000414478.1	PLEKHA6 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology domain containing, family A member 6
chr22_+_31002779 Show fit	0.54	ENST00000215838.3	TCN2 Ensembl NCBI GeneCards UniProt Show fit	transcobalamin II
chr1_-_154909329 Show fit	0.54	ENST00000368467.3	PMVK Ensembl NCBI GeneCards UniProt Show fit	phosphomevalonate kinase
chr12_-_2986107 Show fit	0.54	ENST00000359843.3 ENST00000342628.2 ENST00000361953.3	FOXM1 Ensembl NCBI GeneCards UniProt Show fit	forkhead box M1
chr1_+_20208870 Show fit	0.54	ENST00000375120.3	OTUD3 Ensembl NCBI GeneCards UniProt Show fit	OTU domain containing 3
chr16_-_88923285 Show fit	0.54	ENST00000542788.1 ENST00000569433.1 ENST00000268695.5 ENST00000568311.1	GALNS Ensembl NCBI GeneCards UniProt Show fit	galactosamine (N-acetyl)-6-sulfate sulfatase
chr19_+_10812108 Show fit	0.54	ENST00000250237.5 ENST00000592254.1	QTRT1 Ensembl NCBI GeneCards UniProt Show fit	queuine tRNA-ribosyltransferase 1
chr7_-_2354099 Show fit	0.53	ENST00000222990.3	SNX8 Ensembl NCBI GeneCards UniProt Show fit	sorting nexin 8

Network of associatons between targets according to the STRING database.

First level regulatory network of SREBF1_TFE3

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	14.5	GO:1904637	response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
1.3	5.1	GO:0022007	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.9	3.6	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
0.7	2.1	GO:0043181	vacuolar sequestering(GO:0043181)
0.7	2.0	GO:0002940	tRNA N2-guanine methylation(GO:0002940)
0.6	3.3	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.5	1.6	GO:0002352	B cell negative selection(GO:0002352) post-embryonic camera-type eye morphogenesis(GO:0048597) positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.5	5.8	GO:0000101	sulfur amino acid transport(GO:0000101)
0.5	1.4	GO:1903697	negative regulation of microvillus assembly(GO:1903697)
0.4	3.9	GO:1904715	negative regulation of chaperone-mediated autophagy(GO:1904715)
0.4	3.2	GO:0019262	N-acetylneuraminate catabolic process(GO:0019262)
0.3	1.0	GO:0070407	oxidation-dependent protein catabolic process(GO:0070407)
0.3	1.3	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.3	0.9	GO:0043309	regulation of eosinophil degranulation(GO:0043309) positive regulation of eosinophil degranulation(GO:0043311) regulation of eosinophil activation(GO:1902566) positive regulation of eosinophil activation(GO:1902568)
0.3	1.9	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.3	0.3	GO:0045347	negative regulation of MHC class II biosynthetic process(GO:0045347)
0.3	0.8	GO:0016256	N-glycan processing to lysosome(GO:0016256)
0.2	1.2	GO:0015808	L-alanine transport(GO:0015808)
0.2	0.9	GO:1905176	metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.2	0.9	GO:1901805	beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.2	0.7	GO:0035962	response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.2	2.6	GO:0015889	cobalt ion transport(GO:0006824) cobalamin transport(GO:0015889)
0.2	0.6	GO:0046963	3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.2	2.1	GO:0019264	glycine biosynthetic process from serine(GO:0019264)
0.2	4.3	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520)
0.2	0.6	GO:0061580	colon epithelial cell migration(GO:0061580)
0.2	0.6	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.2	0.8	GO:0016094	polyprenol biosynthetic process(GO:0016094)
0.2	2.4	GO:0033299	secretion of lysosomal enzymes(GO:0033299)
0.2	0.6	GO:0030505	inorganic diphosphate transport(GO:0030505)
0.2	1.0	GO:0006489	dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.2	0.2	GO:0050787	detoxification of mercury ion(GO:0050787)
0.2	0.8	GO:0006566	threonine metabolic process(GO:0006566)
0.2	2.4	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.2	0.2	GO:0072053	renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
0.2	0.9	GO:0046203	spermidine catabolic process(GO:0046203)
0.2	0.7	GO:0002384	hepatic immune response(GO:0002384)
0.2	0.5	GO:0015680	intracellular copper ion transport(GO:0015680)
0.2	0.5	GO:0019287	isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.2	0.9	GO:0043553	negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.2	0.5	GO:0002276	basophil activation involved in immune response(GO:0002276)
0.2	1.1	GO:0072674	multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.2	0.5	GO:0044313	protein K6-linked deubiquitination(GO:0044313)
0.1	0.4	GO:1902871	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.1	0.4	GO:0005985	sucrose metabolic process(GO:0005985)
0.1	0.4	GO:0035606	peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1	0.4	GO:1901207	regulation of heart looping(GO:1901207)
0.1	0.6	GO:1903542	negative regulation of exosomal secretion(GO:1903542)
0.1	0.7	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.1	2.2	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1	0.6	GO:1901857	positive regulation of cellular respiration(GO:1901857)
0.1	0.4	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1	0.9	GO:0050428	purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1	0.4	GO:0016260	selenocysteine biosynthetic process(GO:0016260)
0.1	0.5	GO:0042823	pyridoxal phosphate biosynthetic process(GO:0042823)
0.1	1.8	GO:0060155	platelet dense granule organization(GO:0060155)
0.1	0.5	GO:0006788	heme oxidation(GO:0006788) negative regulation of mast cell cytokine production(GO:0032764)
0.1	0.6	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1	0.8	GO:1903232	melanosome assembly(GO:1903232)
0.1	1.3	GO:1901525	negative regulation of macromitophagy(GO:1901525)
0.1	0.6	GO:0009608	response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.1	0.3	GO:0051596	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1	0.2	GO:1903862	positive regulation of oxidative phosphorylation(GO:1903862)
0.1	1.1	GO:1904378	maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1	0.3	GO:0006043	glucosamine catabolic process(GO:0006043)
0.1	1.6	GO:0035751	regulation of lysosomal lumen pH(GO:0035751)
0.1	0.3	GO:0006286	base-excision repair, base-free sugar-phosphate removal(GO:0006286)
0.1	0.8	GO:0071479	cellular response to ionizing radiation(GO:0071479)
0.1	0.5	GO:0010807	regulation of synaptic vesicle priming(GO:0010807)
0.1	0.8	GO:2001206	positive regulation of osteoclast development(GO:2001206)
0.1	0.7	GO:0071442	positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1	1.9	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.1	1.0	GO:0009133	nucleoside diphosphate biosynthetic process(GO:0009133)
0.1	0.3	GO:0019858	diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966) cytosine metabolic process(GO:0019858)
0.1	0.5	GO:1990910	response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579) response to hypobaric hypoxia(GO:1990910)
0.1	0.6	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
0.1	0.4	GO:0072429	response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1	0.3	GO:0021775	smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.1	0.3	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
0.1	0.4	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.1	1.4	GO:0006782	protoporphyrinogen IX biosynthetic process(GO:0006782)
0.1	1.1	GO:0002191	cap-dependent translational initiation(GO:0002191)
0.1	0.3	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1	0.3	GO:2000393	negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1	0.8	GO:0090238	positive regulation of arachidonic acid secretion(GO:0090238)
0.1	0.6	GO:0071486	cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1	1.5	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.1	0.7	GO:1905232	cellular response to L-glutamate(GO:1905232)
0.1	0.7	GO:1901098	positive regulation of autophagosome maturation(GO:1901098)
0.1	0.6	GO:0070120	leukemia inhibitory factor signaling pathway(GO:0048861) ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.1	0.2	GO:0086021	SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.1	1.9	GO:0007035	vacuolar acidification(GO:0007035)
0.1	1.6	GO:0000338	protein deneddylation(GO:0000338)
0.1	1.3	GO:0044351	macropinocytosis(GO:0044351)
0.1	0.4	GO:0090649	rRNA transport(GO:0051029) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1	1.3	GO:0036149	phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.1	0.8	GO:2000767	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) positive regulation of cytoplasmic translation(GO:2000767)
0.1	0.5	GO:0071461	cellular response to redox state(GO:0071461)
0.1	0.2	GO:0006208	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1	0.2	GO:0060086	circadian temperature homeostasis(GO:0060086)
0.1	0.4	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.1	0.4	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
0.1	0.3	GO:0032902	nerve growth factor production(GO:0032902)
0.1	0.4	GO:2001153	regulation of renal water transport(GO:2001151) positive regulation of renal water transport(GO:2001153)
0.1	0.7	GO:0098967	exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1	0.3	GO:1905123	regulation of endosome organization(GO:1904978) regulation of glucosylceramidase activity(GO:1905123)
0.1	0.6	GO:1905244	regulation of modification of synaptic structure(GO:1905244)
0.1	0.2	GO:0036090	cleavage furrow ingression(GO:0036090)
0.1	0.4	GO:0036369	transcription factor catabolic process(GO:0036369)
0.1	0.4	GO:0015878	biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887)
0.1	1.3	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
0.1	3.3	GO:0097352	autophagosome maturation(GO:0097352)
0.1	0.2	GO:0034164	negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.1	0.2	GO:0021722	superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1	0.5	GO:0072502	cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1	0.6	GO:0045008	depyrimidination(GO:0045008)
0.1	0.2	GO:0050823	peptide stabilization(GO:0050822) peptide antigen stabilization(GO:0050823)
0.1	0.3	GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1	3.8	GO:1903959	regulation of anion transmembrane transport(GO:1903959)
0.1	0.5	GO:1990253	cellular response to leucine starvation(GO:1990253)
0.1	0.3	GO:1902683	regulation of receptor localization to synapse(GO:1902683)
0.1	0.2	GO:0006267	pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1	0.4	GO:1903401	L-lysine transmembrane transport(GO:1903401)
0.1	0.2	GO:1903225	negative regulation of endodermal cell differentiation(GO:1903225)
0.1	0.2	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.1	0.4	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.1	0.2	GO:0045799	positive regulation of chromatin assembly or disassembly(GO:0045799)
0.1	0.2	GO:2001033	negative regulation of double-strand break repair via nonhomologous end joining(GO:2001033)
0.1	0.7	GO:0048484	enteric nervous system development(GO:0048484)
0.1	1.6	GO:1901663	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1	0.2	GO:1901895	negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.1	0.2	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1	0.3	GO:0001828	inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.1	0.2	GO:1902463	protein localization to cell leading edge(GO:1902463)
0.1	0.2	GO:0021816	lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.1	0.2	GO:0046833	positive regulation of RNA export from nucleus(GO:0046833)
0.1	0.1	GO:0014054	positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.1	0.2	GO:1903566	ciliary basal body organization(GO:0032053) positive regulation of protein localization to cilium(GO:1903566)
0.1	0.2	GO:0055099	response to high density lipoprotein particle(GO:0055099)
0.1	0.3	GO:0006001	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1	0.5	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1	1.4	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.1	0.3	GO:0019470	4-hydroxyproline catabolic process(GO:0019470)
0.1	0.3	GO:0018364	peptidyl-glutamine methylation(GO:0018364)
0.1	0.5	GO:0006552	leucine catabolic process(GO:0006552)
0.1	0.2	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.1	0.2	GO:1903347	negative regulation of bicellular tight junction assembly(GO:1903347)
0.1	0.2	GO:0035674	tricarboxylic acid transmembrane transport(GO:0035674)
0.1	1.4	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	0.3	GO:0033133	positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0	0.4	GO:0021546	rhombomere development(GO:0021546)
0.0	0.9	GO:0015886	heme transport(GO:0015886)
0.0	0.9	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.4	GO:0060754	positive regulation of mast cell chemotaxis(GO:0060754)
0.0	0.4	GO:0042908	xenobiotic transport(GO:0042908)
0.0	0.5	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.3	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
0.0	0.2	GO:0035054	embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0	1.7	GO:0006491	N-glycan processing(GO:0006491)
0.0	1.0	GO:0002115	store-operated calcium entry(GO:0002115)
0.0	0.3	GO:0021993	initiation of neural tube closure(GO:0021993)
0.0	0.1	GO:1903774	positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0	0.2	GO:0001971	negative regulation of activation of membrane attack complex(GO:0001971)
0.0	0.1	GO:0019516	lactate oxidation(GO:0019516)
0.0	0.2	GO:1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0	0.3	GO:0016480	negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0	0.5	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.1	GO:0060974	neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.0	0.2	GO:0030240	skeletal muscle thin filament assembly(GO:0030240)
0.0	0.6	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.0	0.4	GO:0070560	protein secretion by platelet(GO:0070560)
0.0	0.3	GO:0045716	positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.0	0.5	GO:0015866	ADP transport(GO:0015866)
0.0	0.2	GO:1904977	lymphatic endothelial cell migration(GO:1904977)
0.0	0.1	GO:1903565	negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0	0.4	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.6	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.0	0.4	GO:0090063	positive regulation of microtubule nucleation(GO:0090063)
0.0	0.2	GO:1904749	regulation of protein localization to nucleolus(GO:1904749)
0.0	0.4	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.0	0.3	GO:0048286	lung alveolus development(GO:0048286)
0.0	0.2	GO:0046618	drug export(GO:0046618)
0.0	0.8	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.0	0.3	GO:0032815	negative regulation of natural killer cell activation(GO:0032815)
0.0	0.2	GO:1901838	positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0	0.6	GO:0046321	positive regulation of fatty acid oxidation(GO:0046321)
0.0	0.3	GO:0051511	regulation of unidimensional cell growth(GO:0051510) negative regulation of unidimensional cell growth(GO:0051511) establishment of cell polarity regulating cell shape(GO:0071964) regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000769) positive regulation of establishment or maintenance of cell polarity regulating cell shape(GO:2000771) regulation of establishment of cell polarity regulating cell shape(GO:2000782) positive regulation of establishment of cell polarity regulating cell shape(GO:2000784) positive regulation of barbed-end actin filament capping(GO:2000814)
0.0	0.3	GO:0045792	negative regulation of cell size(GO:0045792)
0.0	0.2	GO:0044210	'de novo' CTP biosynthetic process(GO:0044210)
0.0	0.2	GO:0015860	purine nucleoside transmembrane transport(GO:0015860)
0.0	0.9	GO:2000615	regulation of histone H3-K9 acetylation(GO:2000615)
0.0	1.3	GO:0030262	apoptotic nuclear changes(GO:0030262)
0.0	0.3	GO:0006049	UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0	0.2	GO:0097527	necroptotic signaling pathway(GO:0097527)
0.0	0.2	GO:0019216	regulation of lipid metabolic process(GO:0019216)
0.0	0.2	GO:0001757	somite specification(GO:0001757)
0.0	0.4	GO:0048278	vesicle docking(GO:0048278)
0.0	0.5	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.2	GO:0010693	negative regulation of alkaline phosphatase activity(GO:0010693)
0.0	1.3	GO:0003299	muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0	0.3	GO:0021603	cranial nerve formation(GO:0021603)
0.0	0.1	GO:0019448	cysteine biosynthetic process from serine(GO:0006535) cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.0	0.1	GO:0009253	peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0	0.2	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.8	GO:0006937	regulation of muscle contraction(GO:0006937)
0.0	0.6	GO:0030050	vesicle transport along actin filament(GO:0030050)
0.0	0.4	GO:2000643	positive regulation of early endosome to late endosome transport(GO:2000643)
0.0	0.3	GO:0040034	regulation of development, heterochronic(GO:0040034) regulation of timing of cell differentiation(GO:0048505)
0.0	0.5	GO:2000781	positive regulation of double-strand break repair(GO:2000781)
0.0	0.2	GO:0046449	allantoin metabolic process(GO:0000255) creatinine metabolic process(GO:0046449)
0.0	0.2	GO:0070384	Harderian gland development(GO:0070384)
0.0	1.0	GO:1900363	regulation of mRNA polyadenylation(GO:1900363)
0.0	0.1	GO:0035948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.0	1.7	GO:1904031	positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.0	0.4	GO:0002315	marginal zone B cell differentiation(GO:0002315)
0.0	1.2	GO:0032211	negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0	0.2	GO:0016246	RNA interference(GO:0016246)
0.0	0.4	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.3	GO:0045218	zonula adherens maintenance(GO:0045218)
0.0	0.1	GO:0060266	positive regulation of respiratory burst involved in inflammatory response(GO:0060265) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.1	GO:0042256	mature ribosome assembly(GO:0042256)
0.0	0.3	GO:1902410	mitotic cytokinetic process(GO:1902410)
0.0	0.3	GO:0040031	snRNA modification(GO:0040031)
0.0	0.3	GO:2000628	regulation of miRNA metabolic process(GO:2000628)
0.0	0.2	GO:0071873	response to norepinephrine(GO:0071873) cellular response to norepinephrine stimulus(GO:0071874)
0.0	0.2	GO:0070295	renal water absorption(GO:0070295)
0.0	0.6	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0	0.6	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0	0.7	GO:0040033	miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0	0.2	GO:0071847	TNFSF11-mediated signaling pathway(GO:0071847)
0.0	0.3	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.1	GO:0000415	negative regulation of histone H3-K36 methylation(GO:0000415)
0.0	0.3	GO:0035303	regulation of dephosphorylation(GO:0035303)
0.0	0.6	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0	0.6	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.2	GO:0031022	nuclear migration along microfilament(GO:0031022)
0.0	0.3	GO:2000394	positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0	0.3	GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0	0.2	GO:1902998	macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0	0.2	GO:0072553	terminal button organization(GO:0072553)
0.0	0.1	GO:0000430	regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0	0.2	GO:0043128	regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.0	0.1	GO:0002232	leukocyte chemotaxis involved in inflammatory response(GO:0002232)
0.0	0.3	GO:0071763	nuclear membrane organization(GO:0071763)
0.0	0.2	GO:1990668	vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane(GO:1990668)
0.0	0.3	GO:1900078	positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0	0.2	GO:0051490	negative regulation of filopodium assembly(GO:0051490)
0.0	0.2	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.0	0.1	GO:0043654	recognition of apoptotic cell(GO:0043654)
0.0	0.2	GO:1904628	response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0	0.4	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.3	GO:0045475	locomotor rhythm(GO:0045475)
0.0	0.1	GO:0050902	leukocyte adhesive activation(GO:0050902)
0.0	0.1	GO:0002725	negative regulation of T cell cytokine production(GO:0002725)
0.0	0.4	GO:0032688	negative regulation of interferon-beta production(GO:0032688)
0.0	0.3	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.4	GO:0009756	carbohydrate mediated signaling(GO:0009756)
0.0	0.3	GO:0038166	angiotensin-activated signaling pathway(GO:0038166)
0.0	0.4	GO:0006069	ethanol oxidation(GO:0006069)
0.0	0.2	GO:0034372	very-low-density lipoprotein particle remodeling(GO:0034372)
0.0	0.1	GO:0043686	co-translational protein modification(GO:0043686)
0.0	0.2	GO:0060272	embryonic skeletal joint morphogenesis(GO:0060272)
0.0	0.2	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.3	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.1	GO:0010636	positive regulation of mitochondrial fusion(GO:0010636)
0.0	0.8	GO:0051894	positive regulation of focal adhesion assembly(GO:0051894)
0.0	0.1	GO:0045720	negative regulation of integrin biosynthetic process(GO:0045720)
0.0	0.3	GO:2000344	positive regulation of acrosome reaction(GO:2000344)
0.0	0.5	GO:0030207	chondroitin sulfate catabolic process(GO:0030207)
0.0	0.3	GO:0035826	rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.0	0.2	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	0.2	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.0	0.5	GO:0006265	DNA topological change(GO:0006265)
0.0	0.6	GO:0015991	ATP hydrolysis coupled proton transport(GO:0015991)
0.0	0.6	GO:0003334	keratinocyte development(GO:0003334)
0.0	0.3	GO:0032836	glomerular basement membrane development(GO:0032836)
0.0	0.2	GO:0023041	neuronal signal transduction(GO:0023041)
0.0	0.4	GO:0035878	nail development(GO:0035878)
0.0	0.4	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.0	GO:0048619	embryonic hindgut morphogenesis(GO:0048619)
0.0	0.1	GO:0042539	hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0	0.2	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.3	GO:0006228	UTP biosynthetic process(GO:0006228)
0.0	0.4	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.2	GO:0040032	post-embryonic body morphogenesis(GO:0040032)
0.0	0.0	GO:0014717	regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.0	0.4	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.3	GO:2000574	regulation of microtubule motor activity(GO:2000574)
0.0	0.4	GO:0001522	pseudouridine synthesis(GO:0001522)
0.0	0.2	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.1	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.7	GO:0040019	positive regulation of embryonic development(GO:0040019)
0.0	0.9	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.0	0.1	GO:0006740	NADPH regeneration(GO:0006740)
0.0	0.8	GO:0033120	positive regulation of RNA splicing(GO:0033120)
0.0	0.5	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0	0.9	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.1	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.0	0.3	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.3	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.3	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.3	GO:0043248	proteasome assembly(GO:0043248)
0.0	1.0	GO:0030818	negative regulation of cAMP biosynthetic process(GO:0030818)
0.0	0.7	GO:0097421	liver regeneration(GO:0097421)
0.0	0.5	GO:0045730	respiratory burst(GO:0045730)
0.0	0.4	GO:0070734	histone H3-K27 methylation(GO:0070734)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	1.1	GO:1904837	beta-catenin-TCF complex assembly(GO:1904837)
0.0	0.1	GO:0038193	thromboxane A2 signaling pathway(GO:0038193)
0.0	0.1	GO:0045683	negative regulation of epidermal cell differentiation(GO:0045605) negative regulation of keratinocyte differentiation(GO:0045617) negative regulation of epidermis development(GO:0045683)
0.0	0.8	GO:0007257	activation of JUN kinase activity(GO:0007257)
0.0	0.2	GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.0	0.2	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0	0.4	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
0.0	0.1	GO:0050760	thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0	0.4	GO:0007172	signal complex assembly(GO:0007172)
0.0	0.5	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.0	0.4	GO:0060575	intestinal epithelial cell differentiation(GO:0060575)
0.0	0.1	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0	0.1	GO:0043096	purine nucleobase salvage(GO:0043096)
0.0	0.3	GO:0043981	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0	0.1	GO:0033292	T-tubule organization(GO:0033292) protein localization to T-tubule(GO:0036371)
0.0	0.2	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.0	0.3	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.0	GO:0045938	positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.0	0.1	GO:0035166	post-embryonic hemopoiesis(GO:0035166) positive regulation of t-circle formation(GO:1904431)
0.0	0.2	GO:0019532	oxalate transport(GO:0019532)
0.0	0.1	GO:0061205	alveolar primary septum development(GO:0061143) paramesonephric duct development(GO:0061205)
0.0	0.0	GO:1904616	regulation of actin filament binding(GO:1904529) negative regulation of actin filament binding(GO:1904530) regulation of actin binding(GO:1904616) negative regulation of actin binding(GO:1904617)
0.0	0.1	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.0	0.2	GO:0031577	spindle checkpoint(GO:0031577)
0.0	0.1	GO:0046689	response to mercury ion(GO:0046689)
0.0	0.1	GO:0034201	response to oleic acid(GO:0034201)
0.0	0.1	GO:0070997	neuron death(GO:0070997)
0.0	0.2	GO:1903874	ferrous iron transport(GO:0015684) ferrous iron transmembrane transport(GO:1903874)
0.0	0.1	GO:0038180	nerve growth factor signaling pathway(GO:0038180)
0.0	1.1	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.0	0.3	GO:0031953	negative regulation of protein autophosphorylation(GO:0031953)
0.0	0.4	GO:0030220	platelet formation(GO:0030220)
0.0	1.4	GO:0010923	negative regulation of phosphatase activity(GO:0010923)
0.0	0.2	GO:0043153	entrainment of circadian clock by photoperiod(GO:0043153)
0.0	0.1	GO:1903054	negative regulation of extracellular matrix organization(GO:1903054)
0.0	0.3	GO:0014066	regulation of phosphatidylinositol 3-kinase signaling(GO:0014066)
0.0	0.1	GO:0035290	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.0	0.3	GO:0097034	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0	0.4	GO:0001696	gastric acid secretion(GO:0001696)
0.0	1.3	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.2	GO:0097264	self proteolysis(GO:0097264)
0.0	0.1	GO:0097475	motor neuron migration(GO:0097475)
0.0	0.3	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	1.0	GO:0045839	negative regulation of mitotic nuclear division(GO:0045839)
0.0	0.1	GO:1903525	regulation of membrane tubulation(GO:1903525) positive regulation of membrane tubulation(GO:1903527)
0.0	0.7	GO:0048635	negative regulation of muscle organ development(GO:0048635)
0.0	0.1	GO:0003382	epithelial cell morphogenesis(GO:0003382)
0.0	0.1	GO:2001171	positive regulation of plasminogen activation(GO:0010756) positive regulation of ATP biosynthetic process(GO:2001171)
0.0	0.3	GO:1903432	regulation of TORC1 signaling(GO:1903432)
0.0	0.5	GO:0008347	glial cell migration(GO:0008347)
0.0	0.2	GO:0043092	L-amino acid import(GO:0043092)
0.0	0.1	GO:0009086	methionine biosynthetic process(GO:0009086)
0.0	0.4	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0	0.2	GO:0060742	epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0	0.1	GO:0044208	'de novo' AMP biosynthetic process(GO:0044208)
0.0	0.1	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.0	0.6	GO:0001919	regulation of receptor recycling(GO:0001919)
0.0	0.2	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.3	GO:0045161	neuronal ion channel clustering(GO:0045161)
0.0	0.6	GO:0043966	histone H3 acetylation(GO:0043966)
0.0	0.1	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0	0.0	GO:0060385	axonogenesis involved in innervation(GO:0060385)
0.0	0.1	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.1	GO:0002860	positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0	0.4	GO:0050913	sensory perception of bitter taste(GO:0050913)
0.0	0.3	GO:0006884	cell volume homeostasis(GO:0006884)
0.0	0.1	GO:2001181	positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-10 secretion(GO:2001181)
0.0	0.3	GO:0060325	face morphogenesis(GO:0060325)
0.0	0.1	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0	0.2	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.0	0.4	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.0	0.1	GO:0001887	selenium compound metabolic process(GO:0001887)
0.0	0.1	GO:0050893	sensory processing(GO:0050893)
0.0	0.2	GO:0034776	response to histamine(GO:0034776) cellular response to histamine(GO:0071420)
0.0	0.0	GO:0090675	intermicrovillar adhesion(GO:0090675)
0.0	0.3	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.0	0.1	GO:0048251	elastic fiber assembly(GO:0048251)
0.0	0.2	GO:0034656	nucleobase-containing small molecule catabolic process(GO:0034656)
0.0	0.2	GO:0019682	glyceraldehyde-3-phosphate metabolic process(GO:0019682)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.4	14.5	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.5	3.5	GO:0098575	lumenal side of lysosomal membrane(GO:0098575)
0.3	3.2	GO:0032010	phagolysosome(GO:0032010)
0.3	1.6	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.2	0.2	GO:0000313	organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.2	1.9	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.2	1.9	GO:0030896	checkpoint clamp complex(GO:0030896)
0.2	0.8	GO:0044611	nuclear pore inner ring(GO:0044611)
0.2	1.3	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.2	0.7	GO:1990796	photoreceptor cell terminal bouton(GO:1990796)
0.2	0.5	GO:0044279	other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.2	1.3	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.2	0.9	GO:0045323	interleukin-1 receptor complex(GO:0045323)
0.2	0.5	GO:0001534	radial spoke(GO:0001534)
0.1	0.1	GO:0035101	FACT complex(GO:0035101)
0.1	0.7	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	1.4	GO:0070552	BRISC complex(GO:0070552)
0.1	0.8	GO:1990131	Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1	0.3	GO:0033186	CAF-1 complex(GO:0033186)
0.1	0.5	GO:0071458	integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.1	1.3	GO:0098560	cytoplasmic side of late endosome membrane(GO:0098560)
0.1	2.4	GO:0042555	MCM complex(GO:0042555)
0.1	1.5	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.1	0.8	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1	0.5	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1	0.3	GO:0031510	SUMO activating enzyme complex(GO:0031510)
0.1	1.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1	0.6	GO:0098837	postsynaptic recycling endosome(GO:0098837)
0.1	1.1	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1	1.2	GO:0000322	storage vacuole(GO:0000322)
0.1	0.3	GO:0031085	BLOC-3 complex(GO:0031085)
0.1	0.9	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.1	0.8	GO:0097413	Lewy body(GO:0097413)
0.1	1.7	GO:0030897	HOPS complex(GO:0030897)
0.1	1.2	GO:0005641	nuclear envelope lumen(GO:0005641)
0.1	0.1	GO:0002177	manchette(GO:0002177)
0.1	0.5	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.1	11.0	GO:0043202	lysosomal lumen(GO:0043202)
0.1	5.4	GO:0016235	aggresome(GO:0016235)
0.1	0.3	GO:0000333	telomerase catalytic core complex(GO:0000333)
0.1	0.2	GO:0036387	nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1	0.2	GO:0005588	collagen type V trimer(GO:0005588)
0.1	0.4	GO:0048476	Holliday junction resolvase complex(GO:0048476)
0.1	0.9	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1	0.6	GO:0097208	alveolar lamellar body(GO:0097208)
0.1	0.4	GO:0089701	U2AF(GO:0089701)
0.1	0.2	GO:0032279	asymmetric synapse(GO:0032279) symmetric synapse(GO:0032280)
0.1	1.3	GO:0000783	telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.1	0.7	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1	0.2	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.9	GO:0030914	STAGA complex(GO:0030914)
0.0	0.4	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.4	GO:0097452	GAIT complex(GO:0097452)
0.0	0.4	GO:0005827	polar microtubule(GO:0005827)
0.0	0.3	GO:0097361	CIA complex(GO:0097361)
0.0	0.6	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	1.9	GO:0005669	transcription factor TFIID complex(GO:0005669)
0.0	0.2	GO:0019034	viral replication complex(GO:0019034)
0.0	0.7	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.8	GO:0060077	inhibitory synapse(GO:0060077)
0.0	0.4	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.0	0.2	GO:0097454	TCR signalosome(GO:0036398) microspike(GO:0044393) Schwann cell microvillus(GO:0097454)
0.0	21.4	GO:0005765	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0	0.4	GO:0005638	lamin filament(GO:0005638)
0.0	0.2	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.4	GO:0042587	glycogen granule(GO:0042587)
0.0	0.9	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.7	GO:0005859	muscle myosin complex(GO:0005859)
0.0	0.3	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.4	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.6	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	1.0	GO:0071011	precatalytic spliceosome(GO:0071011)
0.0	1.3	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.6	GO:0005916	fascia adherens(GO:0005916)
0.0	0.4	GO:0031931	TORC1 complex(GO:0031931)
0.0	1.6	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.1	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.4	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.2	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.2	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0	0.4	GO:0005869	dynactin complex(GO:0005869)
0.0	0.7	GO:0046540	U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0	0.3	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	1.7	GO:0002102	podosome(GO:0002102)
0.0	0.2	GO:0071203	WASH complex(GO:0071203)
0.0	0.2	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.1	GO:0001405	presequence translocase-associated import motor(GO:0001405)
0.0	0.3	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	1.6	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.1	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.0	0.1	GO:0034457	Mpp10 complex(GO:0034457)
0.0	0.2	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	1.4	GO:0005762	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.6	GO:0044665	MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0	0.3	GO:0005915	zonula adherens(GO:0005915)
0.0	0.5	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.4	GO:0010369	chromocenter(GO:0010369)
0.0	0.2	GO:0042382	paraspeckles(GO:0042382)
0.0	0.2	GO:0044327	dendritic spine head(GO:0044327)
0.0	1.3	GO:0031526	brush border membrane(GO:0031526)
0.0	0.3	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.0	2.2	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.1	GO:1990812	growth cone filopodium(GO:1990812)
0.0	0.1	GO:1990246	uniplex complex(GO:1990246)
0.0	0.1	GO:0016342	catenin complex(GO:0016342)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.1	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	1.1	GO:0043198	dendritic shaft(GO:0043198)
0.0	0.4	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.4	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.3	GO:0032585	multivesicular body membrane(GO:0032585)
0.0	0.2	GO:0005610	laminin-5 complex(GO:0005610)
0.0	0.3	GO:0005685	U1 snRNP(GO:0005685)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.8	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	1.8	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0	1.4	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	0.4	GO:0044453	nuclear membrane part(GO:0044453)
0.0	0.3	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.1	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.0	0.1	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.3	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0	0.4	GO:0051233	spindle midzone(GO:0051233)
0.0	0.2	GO:0034451	centriolar satellite(GO:0034451)
0.0	0.3	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.3	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0	1.3	GO:0005776	autophagosome(GO:0005776)
0.0	0.1	GO:0001739	sex chromatin(GO:0001739)
0.0	0.3	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	1.0	GO:0035578	azurophil granule lumen(GO:0035578)
0.0	0.2	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.2	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.1	GO:0036157	outer dynein arm(GO:0036157)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.7	4.1	GO:0046624	sphingolipid transporter activity(GO:0046624)
0.7	2.1	GO:0004574	oligo-1,6-glucosidase activity(GO:0004574)
0.5	1.5	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.5	1.5	GO:0033867	Fas-activated serine/threonine kinase activity(GO:0033867)
0.5	5.8	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
0.5	2.4	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
0.4	1.3	GO:0061711	N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.4	1.3	GO:0004853	uroporphyrinogen decarboxylase activity(GO:0004853)
0.3	1.0	GO:0070362	mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.3	2.0	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.3	13.8	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.3	0.9	GO:0015439	heme-transporting ATPase activity(GO:0015439)
0.3	0.9	GO:0034038	deoxyhypusine synthase activity(GO:0034038)
0.3	1.1	GO:0003943	N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.3	0.9	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.3	0.9	GO:0036313	phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.3	3.8	GO:0004308	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.3	1.1	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
0.2	1.5	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.2	1.2	GO:0015180	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.2	0.7	GO:0070119	ciliary neurotrophic factor binding(GO:0070119)
0.2	0.9	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2	2.6	GO:0031419	cobalamin binding(GO:0031419)
0.2	0.6	GO:0046964	3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.2	2.1	GO:0008732	glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.2	0.6	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.2	0.8	GO:0002094	polyprenyltransferase activity(GO:0002094)
0.2	2.0	GO:1990446	U1 snRNP binding(GO:1990446)
0.2	0.8	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.2	0.6	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.2	0.9	GO:0004348	glucosylceramidase activity(GO:0004348)
0.2	4.2	GO:0015929	hexosaminidase activity(GO:0015929)
0.2	0.5	GO:0048257	3'-flap endonuclease activity(GO:0048257)
0.2	2.8	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2	1.5	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1	0.6	GO:0008534	oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.1	0.4	GO:0042132	fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.1	0.6	GO:0004923	leukemia inhibitory factor receptor activity(GO:0004923)
0.1	3.9	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.1	1.6	GO:0051434	BH3 domain binding(GO:0051434)
0.1	0.6	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
0.1	0.5	GO:0035651	AP-3 adaptor complex binding(GO:0035651)
0.1	0.5	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.1	2.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.1	0.4	GO:0004756	selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1	1.1	GO:0034597	phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.1	0.8	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.1	0.5	GO:0004392	heme oxygenase (decyclizing) activity(GO:0004392)
0.1	0.7	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.1	0.3	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1	0.4	GO:0043891	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1	0.8	GO:0016453	C-acetyltransferase activity(GO:0016453)
0.1	0.5	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1	0.3	GO:0004342	glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1	0.3	GO:0019948	SUMO activating enzyme activity(GO:0019948)
0.1	4.8	GO:0005109	frizzled binding(GO:0005109)
0.1	0.9	GO:0001025	RNA polymerase III transcription factor binding(GO:0001025)
0.1	0.6	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
0.1	0.3	GO:0047389	glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1	0.5	GO:0015321	sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1	0.4	GO:0061628	H3K27me3 modified histone binding(GO:0061628)
0.1	0.9	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.1	0.5	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.1	0.2	GO:0086020	gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.1	1.0	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.1	0.5	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1	0.4	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1	0.4	GO:0004832	valine-tRNA ligase activity(GO:0004832)
0.1	0.8	GO:0004630	phospholipase D activity(GO:0004630)
0.1	0.7	GO:0050544	arachidonic acid binding(GO:0050544)
0.1	0.2	GO:0010309	acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.1	1.1	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.1	0.2	GO:0017057	6-phosphogluconolactonase activity(GO:0017057)
0.1	0.3	GO:0031728	CCR3 chemokine receptor binding(GO:0031728)
0.1	0.8	GO:0008097	5S rRNA binding(GO:0008097)
0.1	0.1	GO:0038052	RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1	0.2	GO:0098770	FBXO family protein binding(GO:0098770)
0.1	1.7	GO:0046961	hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1	0.2	GO:0016534	cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1	0.2	GO:0008384	IkappaB kinase activity(GO:0008384)
0.1	0.4	GO:0003953	NAD+ nucleosidase activity(GO:0003953)
0.1	1.4	GO:0070001	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1	0.5	GO:1904288	BAT3 complex binding(GO:1904288)
0.1	0.6	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.1	0.3	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1	0.4	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.1	0.4	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1	0.2	GO:0004461	lactose synthase activity(GO:0004461)
0.1	0.2	GO:0038131	neuregulin receptor activity(GO:0038131)
0.1	1.1	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.1	0.3	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.1	0.2	GO:0022850	serotonin-gated cation channel activity(GO:0022850)
0.1	0.2	GO:0034041	sterol-transporting ATPase activity(GO:0034041)
0.1	0.4	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.1	0.4	GO:0042577	lipid phosphatase activity(GO:0042577)
0.1	0.9	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.1	0.4	GO:0015189	L-lysine transmembrane transporter activity(GO:0015189)
0.1	0.2	GO:0000994	RNA polymerase III core binding(GO:0000994)
0.1	1.8	GO:0000030	mannosyltransferase activity(GO:0000030)
0.1	0.3	GO:1990189	peptide-serine-N-acetyltransferase activity(GO:1990189)
0.1	0.3	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1	0.6	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
0.1	0.4	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1	0.6	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	1.2	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0	0.3	GO:0001595	angiotensin receptor activity(GO:0001595) angiotensin type II receptor activity(GO:0004945)
0.0	1.1	GO:0017110	nucleoside-diphosphatase activity(GO:0017110)
0.0	0.5	GO:0016641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0	0.7	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.0	0.5	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0	0.4	GO:0004565	beta-galactosidase activity(GO:0004565)
0.0	0.1	GO:0016652	NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0	1.9	GO:0008187	poly-pyrimidine tract binding(GO:0008187)
0.0	0.5	GO:0008565	protein transporter activity(GO:0008565)
0.0	0.3	GO:0070728	leucine binding(GO:0070728)
0.0	0.2	GO:0051185	coenzyme transporter activity(GO:0051185)
0.0	0.2	GO:0045322	unmethylated CpG binding(GO:0045322)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.1	GO:0061714	folic acid receptor activity(GO:0061714)
0.0	0.3	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0	0.3	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
0.0	0.4	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
0.0	4.0	GO:0005507	copper ion binding(GO:0005507)
0.0	0.5	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0	0.5	GO:0000295	adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346)
0.0	0.2	GO:0004572	mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.0	0.4	GO:0001042	RNA polymerase I core binding(GO:0001042)
0.0	0.1	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0	0.2	GO:0015433	peptide antigen-transporting ATPase activity(GO:0015433)
0.0	0.3	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.0	0.3	GO:0070513	death domain binding(GO:0070513)
0.0	0.2	GO:0015307	drug:proton antiporter activity(GO:0015307)
0.0	0.3	GO:0008523	sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0	0.7	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0	0.2	GO:0003883	CTP synthase activity(GO:0003883)
0.0	0.1	GO:0031752	D5 dopamine receptor binding(GO:0031752)
0.0	0.3	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0	0.1	GO:0045127	N-acetylglucosamine kinase activity(GO:0045127)
0.0	0.2	GO:0022897	peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0	0.6	GO:0005149	interleukin-1 receptor binding(GO:0005149)
0.0	0.1	GO:0004122	cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.0	0.2	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.1	GO:0051990	(R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.0	0.4	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.0	0.1	GO:0030617	transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617)
0.0	0.4	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.3	GO:0070740	tubulin-glutamic acid ligase activity(GO:0070740)
0.0	0.1	GO:0004644	phosphoribosylamine-glycine ligase activity(GO:0004637) phosphoribosylformylglycinamidine cyclo-ligase activity(GO:0004641) phosphoribosylglycinamide formyltransferase activity(GO:0004644)
0.0	0.3	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.1	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.0	0.1	GO:0009383	rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.0	0.2	GO:0001848	complement binding(GO:0001848)
0.0	0.1	GO:0004982	N-formyl peptide receptor activity(GO:0004982)
0.0	0.5	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	0.3	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0	0.2	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0	0.1	GO:0005128	erythropoietin receptor binding(GO:0005128)
0.0	0.2	GO:0001054	RNA polymerase I activity(GO:0001054)
0.0	0.6	GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769)
0.0	0.1	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0	0.1	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.2	GO:0016823	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0	0.9	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.9	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	1.0	GO:0017166	vinculin binding(GO:0017166)
0.0	0.2	GO:0043426	MRF binding(GO:0043426)
0.0	1.6	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.6	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.7	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.7	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.1	GO:0016634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0	0.6	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.2	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0	0.1	GO:0002054	nucleobase binding(GO:0002054) purine nucleobase binding(GO:0002060)
0.0	1.3	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.6	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0	0.2	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.3	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.0	0.1	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	2.5	GO:0001618	virus receptor activity(GO:0001618)
0.0	0.2	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.0	0.8	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.1	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0	0.6	GO:0032794	GTPase activating protein binding(GO:0032794)
0.0	0.2	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.8	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.5	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.1	GO:0001016	RNA polymerase III regulatory region DNA binding(GO:0001016)
0.0	0.1	GO:0004487	methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0	0.1	GO:0034057	RNA strand-exchange activity(GO:0034057)
0.0	0.0	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
0.0	0.4	GO:0009982	pseudouridine synthase activity(GO:0009982)
0.0	0.2	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	0.7	GO:0019902	phosphatase binding(GO:0019902)
0.0	0.2	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.0	0.2	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.4	GO:0097602	cullin family protein binding(GO:0097602)
0.0	0.4	GO:0001164	RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0	0.7	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.6	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.2	GO:0019534	toxin transporter activity(GO:0019534)
0.0	0.1	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.0	0.7	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.5	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.1	GO:0004961	thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0	0.2	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.0	0.4	GO:0043522	leucine zipper domain binding(GO:0043522)
0.0	0.2	GO:0051430	corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0	1.2	GO:0003678	DNA helicase activity(GO:0003678)
0.0	1.5	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	3.0	GO:0051082	unfolded protein binding(GO:0051082)
0.0	0.3	GO:0043996	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0	0.4	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.2	GO:0035877	death effector domain binding(GO:0035877)
0.0	0.3	GO:0003995	acyl-CoA dehydrogenase activity(GO:0003995)
0.0	0.1	GO:0052829	inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.2	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.2	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.1	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.2	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.1	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0	1.5	GO:0050660	flavin adenine dinucleotide binding(GO:0050660)
0.0	0.1	GO:0003796	lysozyme activity(GO:0003796)
0.0	0.2	GO:0097157	pre-mRNA intronic binding(GO:0097157)
0.0	0.1	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.2	GO:0051525	NFAT protein binding(GO:0051525)
0.0	0.2	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.4	GO:0001056	RNA polymerase III activity(GO:0001056)
0.0	0.1	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.6	GO:0042287	MHC protein binding(GO:0042287)
0.0	0.1	GO:0030280	structural constituent of epidermis(GO:0030280)
0.0	0.2	GO:0043225	anion transmembrane-transporting ATPase activity(GO:0043225)
0.0	0.9	GO:0042162	telomeric DNA binding(GO:0042162)
0.0	0.5	GO:0005521	lamin binding(GO:0005521)
0.0	0.5	GO:0050431	transforming growth factor beta binding(GO:0050431)
0.0	0.1	GO:0008466	glycogenin glucosyltransferase activity(GO:0008466)
0.0	1.4	GO:0098811	transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0	0.1	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.0	0.0	GO:0005365	myo-inositol transmembrane transporter activity(GO:0005365)
0.0	0.2	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.1	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0	0.5	GO:0071889	14-3-3 protein binding(GO:0071889)
0.0	0.2	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.3	GO:0050700	CARD domain binding(GO:0050700)
0.0	0.2	GO:0050072	m7G(5')pppN diphosphatase activity(GO:0050072)
0.0	0.1	GO:0005537	mannose binding(GO:0005537)
0.0	0.2	GO:0047617	acyl-CoA hydrolase activity(GO:0047617)
0.0	0.2	GO:0000062	fatty-acyl-CoA binding(GO:0000062)
0.0	0.1	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.0	GO:0015928	alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.0	0.8	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.1	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.4	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	1.2	GO:0019213	deacetylase activity(GO:0019213)
0.0	0.6	GO:0030507	spectrin binding(GO:0030507)
0.0	0.1	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)

Gene overrepresentation in C2:CP category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	14.2	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.1	4.9	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.1	1.5	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	2.4	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	1.6	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	3.3	PID ATR PATHWAY	ATR signaling pathway
0.0	0.3	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	0.7	ST STAT3 PATHWAY	STAT3 Pathway
0.0	3.7	PID ILK PATHWAY	Integrin-linked kinase signaling
0.0	1.1	PID MYC PATHWAY	C-MYC pathway
0.0	1.6	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	2.0	PID LKB1 PATHWAY	LKB1 signaling events
0.0	0.5	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	1.6	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	2.0	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.3	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.9	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	1.7	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.3	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.7	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.3	PID IL2 1PATHWAY	IL2-mediated signaling events
0.0	0.5	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	1.2	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	0.4	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.0	0.3	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.3	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.4	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	0.6	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0	0.3	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.4	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.2	PID IFNG PATHWAY	IFN-gamma pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	14.4	REACTOME G1 PHASE	Genes involved in G1 Phase
0.1	2.6	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	5.5	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	4.7	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.1	0.7	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.1	0.4	REACTOME SHC RELATED EVENTS	Genes involved in SHC-related events
0.1	2.5	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.1	3.1	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1	2.1	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.1	2.0	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.1	4.7	REACTOME GLYCOSPHINGOLIPID METABOLISM	Genes involved in Glycosphingolipid metabolism
0.1	0.4	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.1	1.3	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.1	1.6	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	1.7	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	1.4	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.5	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.0	2.0	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	1.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	1.7	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.0	1.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.7	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.5	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	1.2	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	1.7	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.8	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.2	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.6	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	1.4	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.2	REACTOME PI3K CASCADE	Genes involved in PI3K Cascade
0.0	0.5	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.0	0.4	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.5	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.4	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.9	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.7	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.5	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.5	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.2	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.6	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.8	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	1.1	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.3	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	1.2	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.2	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.7	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	3.3	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	0.3	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	1.0	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0	0.7	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.2	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	2.3	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.6	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	2.0	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	2.2	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	2.9	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.3	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.0	0.5	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.0	0.3	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.2	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.4	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.2	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.1	REACTOME TCA CYCLE AND RESPIRATORY ELECTRON TRANSPORT	Genes involved in The citric acid (TCA) cycle and respiratory electron transport
0.0	0.5	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.1	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL

Results for SREBF1_TFE3

Z-value: 1.68

Motif logo

Transcription factors associated with SREBF1_TFE3

Activity-expression correlation:

Activity profile of SREBF1_TFE3 motif

Sorted Z-values of SREBF1_TFE3 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of SREBF1_TFE3

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Gene overrepresentation in cellular_component category:

Gene overrepresentation in molecular_function category:

Gene overrepresentation in C2:CP category:

Gene overrepresentation in C2:CP:REACTOME category: