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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SPIC

Z-value: 0.60

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Transcription factors associated with SPIC

Gene Symbol Gene ID Gene Info
SPIC
ENSG00000166211.6 Spi-C transcription factor

Activity profile of SPIC motif

Sorted Z-values of SPIC motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_39303576 0.36 ENST00000594209.1
LGALS4
lectin, galactoside-binding, soluble, 4
chr1_-_53833812 0.28 ENST00000449958.1
RP11-117D22.2
RP11-117D22.2
chr19_+_42381337 0.26 ENST00000597454.1
ENST00000444740.2
CD79A
CD79a molecule, immunoglobulin-associated alpha
chr2_+_138722028 0.24 ENST00000280096.5
HNMT
histamine N-methyltransferase
chr19_-_2090131 0.20 ENST00000591326.1
MOB3A
MOB kinase activator 3A
chr1_+_112016414 0.19 ENST00000343534.5
ENST00000369718.3
C1orf162
chromosome 1 open reading frame 162
chr6_+_139349903 0.19 ENST00000461027.1
ABRACL
ABRA C-terminal like
chr16_+_28505955 0.19 ENST00000564831.1
ENST00000328423.5
ENST00000431282.1
APOBR
apolipoprotein B receptor
chr17_-_4710288 0.18 ENST00000571067.1
RP11-81A22.5
RP11-81A22.5
chr7_+_74188309 0.17 ENST00000289473.4
ENST00000433458.1
NCF1
neutrophil cytosolic factor 1
chr12_-_54778244 0.17 ENST00000549937.1
ZNF385A
zinc finger protein 385A
chr4_-_177116772 0.17 ENST00000280191.2
SPATA4
spermatogenesis associated 4
chr4_-_103682071 0.17 ENST00000505239.1
MANBA
mannosidase, beta A, lysosomal
chrX_+_47342970 0.16 ENST00000357412.1
CXorf24
chromosome X open reading frame 24
chr7_+_95401877 0.16 ENST00000524053.1
ENST00000324972.6
ENST00000537881.1
ENST00000437599.1
ENST00000359388.4
ENST00000413338.1
DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1
chr17_+_42925270 0.15 ENST00000253410.2
ENST00000587021.1
HIGD1B
HIG1 hypoxia inducible domain family, member 1B
chr16_-_4850471 0.15 ENST00000592019.1
ENST00000586153.1
ROGDI
rogdi homolog (Drosophila)
chr2_+_175352114 0.15 ENST00000444196.1
ENST00000417038.1
ENST00000606406.1
AC010894.3
AC010894.3
chr19_+_35940486 0.14 ENST00000246549.2
FFAR2
free fatty acid receptor 2
chr2_-_64751227 0.14 ENST00000561559.1
RP11-568N6.1
RP11-568N6.1
chr17_-_20370847 0.14 ENST00000423676.3
ENST00000324290.5
LGALS9B
lectin, galactoside-binding, soluble, 9B
chr18_-_61089611 0.14 ENST00000591519.1
VPS4B
vacuolar protein sorting 4 homolog B (S. cerevisiae)
chr11_+_327171 0.13 ENST00000534483.1
ENST00000524824.1
ENST00000531076.1
RP11-326C3.12
RP11-326C3.12
chr12_+_112451222 0.13 ENST00000552052.1
ERP29
endoplasmic reticulum protein 29
chr4_+_123653882 0.13 ENST00000433287.1
BBS12
Bardet-Biedl syndrome 12
chr3_+_184530173 0.13 ENST00000453056.1
VPS8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr5_-_138862326 0.13 ENST00000330794.4
TMEM173
transmembrane protein 173
chr4_-_25161996 0.13 ENST00000513285.1
ENST00000382103.2
SEPSECS
Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase
chr3_+_156544057 0.13 ENST00000498839.1
ENST00000470811.1
ENST00000356539.4
ENST00000483177.1
ENST00000477399.1
ENST00000491763.1
LEKR1
leucine, glutamate and lysine rich 1
chr2_+_217363826 0.13 ENST00000441179.2
RPL37A
ribosomal protein L37a
chr19_+_35939154 0.13 ENST00000599180.2
FFAR2
free fatty acid receptor 2
chr7_+_150382781 0.13 ENST00000223293.5
ENST00000474605.1
GIMAP2
GTPase, IMAP family member 2
chr11_-_7698453 0.12 ENST00000524608.1
CYB5R2
cytochrome b5 reductase 2
chr1_-_183560011 0.12 ENST00000367536.1
NCF2
neutrophil cytosolic factor 2
chr1_+_150245177 0.12 ENST00000369098.3
C1orf54
chromosome 1 open reading frame 54
chr1_+_151009054 0.12 ENST00000295294.7
BNIPL
BCL2/adenovirus E1B 19kD interacting protein like
chr10_-_1034237 0.12 ENST00000381466.1
AL359878.1
Uncharacterized protein
chr19_+_35810164 0.12 ENST00000598537.1
CD22
CD22 molecule
chr7_+_108210012 0.12 ENST00000249356.3
DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr5_-_146461027 0.12 ENST00000394410.2
ENST00000508267.1
ENST00000504198.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr1_-_242162375 0.12 ENST00000357246.3
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr3_+_57094469 0.12 ENST00000334325.1
SPATA12
spermatogenesis associated 12
chr17_-_72619869 0.12 ENST00000392619.1
ENST00000426295.2
CD300E
CD300e molecule
chr9_+_215158 0.11 ENST00000479404.1
DOCK8
dedicator of cytokinesis 8
chr6_+_26087646 0.11 ENST00000309234.6
HFE
hemochromatosis
chr14_-_67826538 0.11 ENST00000553687.1
ATP6V1D
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
chr15_-_90233907 0.11 ENST00000561224.1
PEX11A
peroxisomal biogenesis factor 11 alpha
chrX_-_51239425 0.11 ENST00000375992.3
NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr3_-_142720267 0.11 ENST00000597953.1
RP11-91G21.1
RP11-91G21.1
chr11_-_119993979 0.11 ENST00000524816.3
ENST00000525327.1
TRIM29
tripartite motif containing 29
chr15_-_33360342 0.11 ENST00000558197.1
FMN1
formin 1
chr6_-_56707943 0.11 ENST00000370769.4
ENST00000421834.2
ENST00000312431.6
ENST00000361203.3
ENST00000523817.1
DST
dystonin
chr19_+_9732156 0.11 ENST00000586614.1
ENST00000587536.1
ENST00000591056.1
ENST00000592851.1
C19orf82
chromosome 19 open reading frame 82
chr7_-_105319536 0.11 ENST00000477775.1
ATXN7L1
ataxin 7-like 1
chr6_-_170151603 0.11 ENST00000366774.3
TCTE3
t-complex-associated-testis-expressed 3
chr5_+_174151536 0.10 ENST00000239243.6
ENST00000507785.1
MSX2
msh homeobox 2
chr22_-_37880543 0.10 ENST00000442496.1
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr14_+_88471468 0.10 ENST00000267549.3
GPR65
G protein-coupled receptor 65
chr19_+_49838653 0.10 ENST00000598095.1
ENST00000426897.2
ENST00000323906.4
ENST00000535669.2
ENST00000597602.1
ENST00000595660.1
CD37
CD37 molecule
chr2_+_63277927 0.10 ENST00000282549.2
OTX1
orthodenticle homeobox 1
chr6_+_116782527 0.10 ENST00000368606.3
ENST00000368605.1
FAM26F
family with sequence similarity 26, member F
chr2_+_217363793 0.10 ENST00000456586.1
ENST00000598925.1
ENST00000427280.2
RPL37A
ribosomal protein L37a
chr6_+_139349817 0.10 ENST00000367660.3
ABRACL
ABRA C-terminal like
chr6_-_56708459 0.10 ENST00000370788.2
DST
dystonin
chr1_+_156698743 0.10 ENST00000524343.1
RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr4_+_123653807 0.10 ENST00000314218.3
ENST00000542236.1
BBS12
Bardet-Biedl syndrome 12
chr10_+_81891416 0.10 ENST00000372270.2
PLAC9
placenta-specific 9
chr12_+_76653611 0.10 ENST00000550380.1
RP11-54A9.1
RP11-54A9.1
chr19_+_58694742 0.10 ENST00000597528.1
ENST00000594839.1
ZNF274
zinc finger protein 274
chr2_+_219724544 0.10 ENST00000233948.3
WNT6
wingless-type MMTV integration site family, member 6
chr8_+_39770803 0.10 ENST00000518237.1
IDO1
indoleamine 2,3-dioxygenase 1
chr8_+_86019382 0.10 ENST00000360375.3
LRRCC1
leucine rich repeat and coiled-coil centrosomal protein 1
chr14_-_89883412 0.10 ENST00000557258.1
FOXN3
forkhead box N3
chr8_+_97657531 0.10 ENST00000519900.1
ENST00000517742.1
CPQ
carboxypeptidase Q
chr15_+_67547113 0.10 ENST00000512104.1
ENST00000358767.3
ENST00000546225.1
IQCH
IQ motif containing H
chr2_-_264024 0.10 ENST00000403712.2
ENST00000356150.5
ENST00000405430.1
SH3YL1
SH3 and SYLF domain containing 1
chr16_+_80574854 0.09 ENST00000305904.6
ENST00000568035.1
DYNLRB2
dynein, light chain, roadblock-type 2
chr18_-_11908272 0.09 ENST00000592977.1
ENST00000590501.1
ENST00000586844.1
MPPE1
metallophosphoesterase 1
chr19_-_12780211 0.09 ENST00000597961.1
ENST00000598732.1
ENST00000222190.5
CTD-2192J16.24
WDR83OS
Uncharacterized protein
WD repeat domain 83 opposite strand
chr12_-_110888103 0.09 ENST00000426440.1
ENST00000228825.7
ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr6_+_31553978 0.09 ENST00000376096.1
ENST00000376099.1
ENST00000376110.3
LST1
leukocyte specific transcript 1
chrX_+_123095860 0.09 ENST00000428941.1
STAG2
stromal antigen 2
chr1_+_150245099 0.09 ENST00000369099.3
C1orf54
chromosome 1 open reading frame 54
chr1_-_9129735 0.09 ENST00000377424.4
SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr1_-_183559693 0.09 ENST00000367535.3
ENST00000413720.1
ENST00000418089.1
NCF2
neutrophil cytosolic factor 2
chr7_-_102252589 0.09 ENST00000520042.1
RASA4
RAS p21 protein activator 4
chr1_-_71546690 0.09 ENST00000254821.6
ZRANB2
zinc finger, RAN-binding domain containing 2
chr10_-_99161033 0.09 ENST00000315563.6
ENST00000370992.4
ENST00000414986.1
RRP12
ribosomal RNA processing 12 homolog (S. cerevisiae)
chr11_+_94706804 0.09 ENST00000335080.5
KDM4D
lysine (K)-specific demethylase 4D
chr2_+_217363559 0.09 ENST00000600880.1
ENST00000446558.1
RPL37A
ribosomal protein L37a
chr5_-_138861926 0.09 ENST00000510817.1
TMEM173
transmembrane protein 173
chr11_-_71639446 0.09 ENST00000534704.1
RP11-849H4.2
Putative short transient receptor potential channel 2-like protein
chr19_-_14016877 0.09 ENST00000454313.1
ENST00000591586.1
ENST00000346736.2
C19orf57
chromosome 19 open reading frame 57
chr7_-_32529973 0.09 ENST00000410044.1
ENST00000409987.1
ENST00000409782.1
ENST00000450169.2
LSM5
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr3_-_145940126 0.08 ENST00000498625.1
PLSCR4
phospholipid scramblase 4
chr17_+_74723031 0.08 ENST00000586200.1
METTL23
methyltransferase like 23
chr15_+_75335604 0.08 ENST00000563393.1
PPCDC
phosphopantothenoylcysteine decarboxylase
chr12_+_51318513 0.08 ENST00000332160.4
METTL7A
methyltransferase like 7A
chr7_-_128001658 0.08 ENST00000489835.2
ENST00000464607.1
ENST00000489517.1
ENST00000446477.2
ENST00000535159.1
ENST00000435512.1
ENST00000495931.1
PRRT4
proline-rich transmembrane protein 4
chr11_+_112047087 0.08 ENST00000526088.1
ENST00000532593.1
ENST00000531169.1
BCO2
beta-carotene oxygenase 2
chr14_-_45722360 0.08 ENST00000451174.1
MIS18BP1
MIS18 binding protein 1
chrX_+_51075658 0.08 ENST00000356450.2
NUDT10
nudix (nucleoside diphosphate linked moiety X)-type motif 10
chr9_-_134145880 0.08 ENST00000372269.3
ENST00000464831.1
FAM78A
family with sequence similarity 78, member A
chr5_-_114632307 0.08 ENST00000506442.1
ENST00000379611.5
CCDC112
coiled-coil domain containing 112
chr17_-_74489215 0.08 ENST00000585701.1
ENST00000591192.1
ENST00000589526.1
RHBDF2
rhomboid 5 homolog 2 (Drosophila)
chr14_-_55738788 0.08 ENST00000556183.1
RP11-665C16.6
RP11-665C16.6
chr3_-_47324008 0.08 ENST00000425853.1
KIF9
kinesin family member 9
chr15_-_75917955 0.08 ENST00000568162.1
ENST00000563875.1
SNUPN
snurportin 1
chr6_-_90121789 0.08 ENST00000359203.3
RRAGD
Ras-related GTP binding D
chr17_+_7487146 0.08 ENST00000396501.4
ENST00000584378.1
ENST00000423172.2
ENST00000579445.1
ENST00000585217.1
ENST00000581380.1
MPDU1
mannose-P-dolichol utilization defect 1
chr2_-_175351744 0.08 ENST00000295500.4
ENST00000392552.2
ENST00000392551.2
GPR155
G protein-coupled receptor 155
chr22_-_30942669 0.08 ENST00000402034.2
SEC14L6
SEC14-like 6 (S. cerevisiae)
chr19_-_9695169 0.08 ENST00000586602.1
ZNF121
zinc finger protein 121
chr5_+_115177178 0.08 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr1_+_171283331 0.07 ENST00000367749.3
FMO4
flavin containing monooxygenase 4
chr5_-_159797627 0.07 ENST00000393975.3
C1QTNF2
C1q and tumor necrosis factor related protein 2
chr4_-_164534657 0.07 ENST00000339875.5
MARCH1
membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
chr6_+_148593425 0.07 ENST00000367469.1
SASH1
SAM and SH3 domain containing 1
chr1_+_151009035 0.07 ENST00000368931.3
BNIPL
BCL2/adenovirus E1B 19kD interacting protein like
chr16_+_25703274 0.07 ENST00000331351.5
HS3ST4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr19_+_10222189 0.07 ENST00000321826.4
P2RY11
purinergic receptor P2Y, G-protein coupled, 11
chr9_-_7800067 0.07 ENST00000358227.4
TMEM261
transmembrane protein 261
chr10_+_22605374 0.07 ENST00000448361.1
COMMD3
COMM domain containing 3
chr12_-_15114603 0.07 ENST00000228945.4
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr6_-_8435706 0.07 ENST00000379660.4
SLC35B3
solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3
chr19_-_5838768 0.07 ENST00000527106.1
ENST00000531199.1
ENST00000529165.1
FUT6
fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
chr14_+_74417192 0.07 ENST00000554320.1
COQ6
coenzyme Q6 monooxygenase
chrX_-_63615297 0.07 ENST00000374852.3
ENST00000453546.1
MTMR8
myotubularin related protein 8
chr9_-_5304432 0.07 ENST00000416837.1
ENST00000308420.3
RLN2
relaxin 2
chr15_-_90234006 0.07 ENST00000300056.3
ENST00000559170.1
PEX11A
peroxisomal biogenesis factor 11 alpha
chr19_+_1752372 0.07 ENST00000382349.4
ONECUT3
one cut homeobox 3
chr7_+_139025875 0.07 ENST00000297534.6
C7orf55
chromosome 7 open reading frame 55
chr1_+_212968025 0.07 ENST00000530399.2
TATDN3
TatD DNase domain containing 3
chr11_+_6226782 0.07 ENST00000316375.2
C11orf42
chromosome 11 open reading frame 42
chr16_+_57576584 0.07 ENST00000340339.4
GPR114
G protein-coupled receptor 114
chr9_+_273038 0.07 ENST00000487230.1
ENST00000469391.1
DOCK8
dedicator of cytokinesis 8
chr6_+_116601330 0.07 ENST00000449314.1
ENST00000453463.1
RP1-93H18.1
RP1-93H18.1
chr4_-_70653673 0.07 ENST00000512870.1
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr19_+_56813305 0.07 ENST00000593151.1
AC006116.20
Uncharacterized protein
chr11_+_1874200 0.07 ENST00000311604.3
LSP1
lymphocyte-specific protein 1
chr5_-_114598548 0.07 ENST00000379615.3
ENST00000419445.1
PGGT1B
protein geranylgeranyltransferase type I, beta subunit
chr16_-_15736881 0.07 ENST00000540441.2
KIAA0430
KIAA0430
chr2_+_233925064 0.07 ENST00000359570.5
ENST00000538935.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr4_-_103682145 0.07 ENST00000226578.4
MANBA
mannosidase, beta A, lysosomal
chr19_+_19626531 0.07 ENST00000507754.4
NDUFA13
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr5_+_68530668 0.07 ENST00000506563.1
CDK7
cyclin-dependent kinase 7
chr1_+_145470504 0.07 ENST00000323397.4
ANKRD34A
ankyrin repeat domain 34A
chr10_+_85954377 0.07 ENST00000332904.3
ENST00000372117.3
CDHR1
cadherin-related family member 1
chrY_+_15016725 0.07 ENST00000336079.3
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr3_-_20227720 0.07 ENST00000412997.1
SGOL1
shugoshin-like 1 (S. pombe)
chr7_-_158937544 0.07 ENST00000421760.2
ENST00000402066.1
VIPR2
vasoactive intestinal peptide receptor 2
chr11_-_62995986 0.07 ENST00000403374.2
SLC22A25
solute carrier family 22, member 25
chr4_-_99578789 0.07 ENST00000511651.1
ENST00000505184.1
TSPAN5
tetraspanin 5
chr1_+_33938236 0.07 ENST00000361328.3
ENST00000373413.2
ZSCAN20
zinc finger and SCAN domain containing 20
chr5_-_40835303 0.07 ENST00000509877.1
ENST00000508493.1
ENST00000274242.5
RPL37
ribosomal protein L37
chr9_+_74526384 0.07 ENST00000334731.2
ENST00000377031.3
C9orf85
chromosome 9 open reading frame 85
chr16_-_66968265 0.07 ENST00000567511.1
ENST00000422424.2
FAM96B
family with sequence similarity 96, member B
chr20_+_48892848 0.07 ENST00000422459.1
RP11-290F20.3
RP11-290F20.3
chr2_+_85822857 0.07 ENST00000306368.4
ENST00000414390.1
ENST00000456023.1
RNF181
ring finger protein 181
chr15_-_33360085 0.07 ENST00000334528.9
FMN1
formin 1
chrX_-_47489244 0.07 ENST00000469388.1
ENST00000396992.3
ENST00000377005.2
CFP
complement factor properdin
chr10_-_119806085 0.07 ENST00000355624.3
RAB11FIP2
RAB11 family interacting protein 2 (class I)
chr9_+_5510492 0.07 ENST00000397745.2
PDCD1LG2
programmed cell death 1 ligand 2
chr10_+_18948311 0.07 ENST00000377275.3
ARL5B
ADP-ribosylation factor-like 5B
chr17_+_18380051 0.06 ENST00000581545.1
ENST00000582333.1
ENST00000328114.6
ENST00000412421.2
ENST00000583322.1
ENST00000584941.1
LGALS9C
lectin, galactoside-binding, soluble, 9C
chr1_+_203830703 0.06 ENST00000414487.2
SNRPE
small nuclear ribonucleoprotein polypeptide E
chr12_+_12223867 0.06 ENST00000308721.5
BCL2L14
BCL2-like 14 (apoptosis facilitator)
chrX_-_107018969 0.06 ENST00000372383.4
TSC22D3
TSC22 domain family, member 3
chr6_-_110012380 0.06 ENST00000424296.2
ENST00000341338.6
ENST00000368948.2
ENST00000285397.5
AK9
adenylate kinase 9
chr4_-_47916543 0.06 ENST00000507489.1
NFXL1
nuclear transcription factor, X-box binding-like 1
chr19_+_38826477 0.06 ENST00000409410.2
ENST00000215069.4
CATSPERG
catsper channel auxiliary subunit gamma
chr15_-_75918500 0.06 ENST00000569817.1
SNUPN
snurportin 1
chr11_-_68671244 0.06 ENST00000567045.1
ENST00000450904.2
MRPL21
mitochondrial ribosomal protein L21
chr5_-_60458179 0.06 ENST00000507416.1
ENST00000339020.3
SMIM15
small integral membrane protein 15
chr19_-_2236290 0.06 ENST00000591099.2
ENST00000586608.2
ENST00000326631.2
ENST00000587962.2
PLEKHJ1
pleckstrin homology domain containing, family J member 1
chr15_-_90233866 0.06 ENST00000561257.1
PEX11A
peroxisomal biogenesis factor 11 alpha
chr3_-_49142504 0.06 ENST00000306125.6
ENST00000420147.2
QARS
glutaminyl-tRNA synthetase
chr3_+_10157276 0.06 ENST00000530758.1
ENST00000256463.6
BRK1
BRICK1, SCAR/WAVE actin-nucleating complex subunit
chr17_+_68047418 0.06 ENST00000586373.1
ENST00000588782.1
LINC01028
long intergenic non-protein coding RNA 1028
chr11_-_32816156 0.06 ENST00000531481.1
ENST00000335185.5
CCDC73
coiled-coil domain containing 73
chrX_-_100604184 0.06 ENST00000372902.3
TIMM8A
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr12_-_113841678 0.06 ENST00000552280.1
ENST00000257549.4
SDS
serine dehydratase
chr19_+_58898627 0.06 ENST00000598098.1
ENST00000598495.1
ENST00000196551.3
ENST00000596046.1
RPS5
ribosomal protein S5
chr4_-_99578776 0.06 ENST00000515287.1
TSPAN5
tetraspanin 5
chr4_+_159727272 0.06 ENST00000379346.3
FNIP2
folliculin interacting protein 2
chr2_-_242211359 0.06 ENST00000444092.1
HDLBP
high density lipoprotein binding protein
chr5_+_102455853 0.06 ENST00000515845.1
ENST00000321521.9
ENST00000507921.1
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr14_+_32414059 0.06 ENST00000553330.1
RP11-187E13.1
Uncharacterized protein
chr17_-_48450534 0.06 ENST00000503633.1
ENST00000442592.3
ENST00000225969.4
MRPL27
mitochondrial ribosomal protein L27
chr5_+_6448736 0.06 ENST00000399816.3
UBE2QL1
ubiquitin-conjugating enzyme E2Q family-like 1
chr8_+_121457642 0.06 ENST00000305949.1
MTBP
Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa
chr2_+_102758210 0.06 ENST00000450319.1
IL1R1
interleukin 1 receptor, type I
chr9_-_34620440 0.06 ENST00000421919.1
ENST00000378911.3
ENST00000477738.2
ENST00000341694.2
ENST00000259632.7
ENST00000378913.2
ENST00000378916.4
ENST00000447983.2
DCTN3
dynactin 3 (p22)
chr4_-_47916613 0.06 ENST00000381538.3
ENST00000329043.3
NFXL1
nuclear transcription factor, X-box binding-like 1
chr9_+_214842 0.06 ENST00000453981.1
ENST00000432829.2
DOCK8
dedicator of cytokinesis 8
chr5_+_102455968 0.06 ENST00000358359.3
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr1_-_175161890 0.06 ENST00000545251.2
ENST00000423313.1
KIAA0040
KIAA0040
chr18_-_34408802 0.06 ENST00000590842.1
TPGS2
tubulin polyglutamylase complex subunit 2
chr5_+_443280 0.06 ENST00000508022.1
EXOC3
exocyst complex component 3
chr19_-_13213662 0.06 ENST00000264824.4
LYL1
lymphoblastic leukemia derived sequence 1

Network of associatons between targets according to the STRING database.

First level regulatory network of SPIC

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232)
0.1 0.2 GO:0061485 memory T cell proliferation(GO:0061485)
0.0 0.2 GO:1903722 negative regulation of exosomal secretion(GO:1903542) regulation of centriole elongation(GO:1903722)
0.0 0.1 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.0 0.1 GO:0006425 glutaminyl-tRNA aminoacylation(GO:0006425)
0.0 0.1 GO:0002316 follicular B cell differentiation(GO:0002316)
0.0 0.1 GO:0051795 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.0 0.1 GO:0001300 chronological cell aging(GO:0001300)
0.0 0.2 GO:0040009 regulation of growth rate(GO:0040009)
0.0 0.2 GO:0061015 snRNA import into nucleus(GO:0061015)
0.0 0.2 GO:0071543 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.2 GO:0044375 peroxisome membrane biogenesis(GO:0016557) regulation of peroxisome size(GO:0044375)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.1 GO:0036269 swimming behavior(GO:0036269)
0.0 0.1 GO:2001193 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) negative regulation of CD8-positive, alpha-beta T cell activation(GO:2001186) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.0 0.1 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.1 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.0 0.2 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.1 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.1 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.0 0.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.1 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.1 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0061570 dADP phosphorylation(GO:0006174) dGDP phosphorylation(GO:0006186) AMP phosphorylation(GO:0006756) CDP phosphorylation(GO:0061508) dAMP phosphorylation(GO:0061565) CMP phosphorylation(GO:0061566) dCMP phosphorylation(GO:0061567) GDP phosphorylation(GO:0061568) UDP phosphorylation(GO:0061569) dCDP phosphorylation(GO:0061570) TDP phosphorylation(GO:0061571)
0.0 0.1 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.0 0.1 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.0 0.1 GO:0071725 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.0 0.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.1 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.0 0.0 GO:0038163 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.0 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.2 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.0 0.1 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.5 GO:0045730 respiratory burst(GO:0045730)
0.0 0.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.0 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.0 0.0 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.0 GO:0033341 regulation of collagen binding(GO:0033341)
0.0 0.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.1 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.0 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.0 0.0 GO:1990167 protein K27-linked deubiquitination(GO:1990167) protein K33-linked deubiquitination(GO:1990168)
0.0 0.2 GO:0033160 positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.0 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.1 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.1 GO:2000330 positive regulation of T-helper 17 cell lineage commitment(GO:2000330)
0.0 0.0 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.0 0.4 GO:0032010 phagolysosome(GO:0032010)
0.0 0.3 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.2 GO:0031673 H zone(GO:0031673)
0.0 0.1 GO:0072563 endothelial microparticle(GO:0072563)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.1 GO:0070985 TFIIK complex(GO:0070985)
0.0 0.0 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.0 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.2 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.1 GO:0036128 CatSper complex(GO:0036128)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.4 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
0.0 0.1 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.0 0.2 GO:0052845 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.1 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.0 0.2 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0030109 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107) HLA-B specific inhibitory MHC class I receptor activity(GO:0030109) inhibitory MHC class I receptor activity(GO:0032396)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.1 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.0 0.0 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0 0.1 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.0 0.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.1 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.0 GO:0004040 amidase activity(GO:0004040)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.0 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.0 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.0 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.0 0.1 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.2 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.0 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.0 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.0 0.1 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.0 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.0 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand