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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for SOX5
Z-value: 0.89
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Transcription factors associated with SOX5
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| SOX5 | hg19_v2_chr12_-_24103954_24103972 | 0.41 | 4.2e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr9_-_98268883 Show fit | 0.68 |
ENST00000551630.1
ENST00000548420.1 |
patched 1 |
|
| chr2_-_25451065 Show fit | 0.49 |
ENST00000606328.1
|
RP11-458N5.1 |
|
| chr16_+_30934376 Show fit | 0.48 |
ENST00000562798.1
ENST00000471231.2 |
F-box and leucine-rich repeat protein 19 |
|
| chr14_-_92414294 Show fit | 0.44 |
ENST00000554468.1
|
fibulin 5 |
|
| chr1_-_40367668 Show fit | 0.38 |
ENST00000397332.2
ENST00000429311.1 |
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog |
|
| chr14_-_92414055 Show fit | 0.36 |
ENST00000342058.4
|
fibulin 5 |
|
| chr8_-_128231299 Show fit | 0.32 |
ENST00000500112.1
|
colon cancer associated transcript 1 (non-protein coding) |
|
| chr6_+_12290586 Show fit | 0.31 |
ENST00000379375.5
|
endothelin 1 |
|
| chr5_-_138780159 Show fit | 0.29 |
ENST00000512473.1
ENST00000515581.1 ENST00000515277.1 |
DnaJ (Hsp40) homolog, subfamily C, member 18 |
|
| chr1_+_43637996 Show fit | 0.27 |
ENST00000528956.1
ENST00000529956.1 |
WD repeat domain 65 |
Network of associatons between targets according to the STRING database.
First level regulatory network of SOX5
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.1 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.1 | 0.7 | GO:0010157 | response to chlorate(GO:0010157) |
| 0.1 | 0.4 | GO:0007499 | ectoderm and mesoderm interaction(GO:0007499) |
| 0.1 | 0.4 | GO:0045607 | regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980) |
| 0.1 | 0.4 | GO:1902952 | positive regulation of dendritic spine maintenance(GO:1902952) |
| 0.1 | 0.3 | GO:0030185 | nitric oxide transport(GO:0030185) |
| 0.1 | 0.3 | GO:1903045 | neural crest cell migration involved in sympathetic nervous system development(GO:1903045) |
| 0.0 | 0.3 | GO:1902748 | mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748) |
| 0.0 | 0.3 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
| 0.0 | 0.2 | GO:0072709 | cellular response to sorbitol(GO:0072709) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.1 | GO:0071953 | elastic fiber(GO:0071953) |
| 0.1 | 0.7 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 0.1 | 0.3 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
| 0.0 | 0.3 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
| 0.0 | 0.3 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
| 0.0 | 0.2 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.0 | 0.2 | GO:0030478 | actin cap(GO:0030478) |
| 0.0 | 0.2 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.0 | 0.1 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
| 0.0 | 0.1 | GO:0000806 | Y chromosome(GO:0000806) cyclin A1-CDK2 complex(GO:0097123) cyclin A2-CDK2 complex(GO:0097124) cyclin E1-CDK2 complex(GO:0097134) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.7 | GO:0005119 | smoothened binding(GO:0005119) |
| 0.0 | 0.5 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.0 | 0.4 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.1 | 0.3 | GO:0004113 | 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113) |
| 0.1 | 0.3 | GO:0031708 | endothelin B receptor binding(GO:0031708) |
| 0.0 | 0.3 | GO:0045499 | chemorepellent activity(GO:0045499) |
| 0.1 | 0.2 | GO:0050146 | nucleoside phosphotransferase activity(GO:0050146) |
| 0.0 | 0.2 | GO:0097642 | calcitonin family receptor activity(GO:0097642) |
| 0.0 | 0.2 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.0 | 0.2 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.9 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.0 | 0.2 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |