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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for SOX13_SOX12

Z-value: 1.09

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Transcription factors associated with SOX13_SOX12

Gene Symbol Gene ID Gene Info
ENSG00000143842.10 SRY-box transcription factor 13
ENSG00000177732.6 SRY-box transcription factor 12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
SOX12hg19_v2_chr20_+_306221_306239-0.364.9e-01Click!
SOX13hg19_v2_chr1_+_204042723_204042784-0.305.7e-01Click!

Activity profile of SOX13_SOX12 motif

Sorted Z-values of SOX13_SOX12 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_174818390 0.82 ENST00000509968.1
ENST00000512263.1
RP11-161D15.1
chr21_+_35553045 0.77 ENST00000416145.1
ENST00000430922.1
ENST00000419881.2
long intergenic non-protein coding RNA 310
chr2_+_102927962 0.72 ENST00000233954.1
ENST00000393393.3
ENST00000410040.1
interleukin 1 receptor-like 1
interleukin 18 receptor 1
chr7_-_81635106 0.57 ENST00000443883.1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr4_+_95128748 0.56 ENST00000359052.4
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr9_+_26746951 0.55 ENST00000523363.1
RP11-18A15.1
chr17_-_38821373 0.54 ENST00000394052.3
keratin 222
chr21_+_38593701 0.53 ENST00000440629.1
AP001432.14
chr8_+_32579271 0.53 ENST00000518084.1
neuregulin 1
chr20_-_5426380 0.52 ENST00000609252.1
ENST00000422352.1
long intergenic non-protein coding RNA 658
chr5_+_40841410 0.50 ENST00000381677.3
caspase recruitment domain family, member 6
chr11_-_85393886 0.50 ENST00000534224.1
CREB/ATF bZIP transcription factor
chr4_-_105416039 0.50 ENST00000394767.2
CXXC finger protein 4
chr4_+_95128996 0.49 ENST00000457823.2
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chrM_+_3299 0.49 ENST00000361390.2
mitochondrially encoded NADH dehydrogenase 1
chr19_+_21106081 0.49 ENST00000300540.3
ENST00000595854.1
ENST00000601284.1
ENST00000328178.8
ENST00000599885.1
ENST00000596476.1
ENST00000345030.6
zinc finger protein 85
chr12_+_11081828 0.47 ENST00000381847.3
ENST00000396400.3
proline-rich protein HaeIII subfamily 2
chr6_-_56492816 0.47 ENST00000522360.1
dystonin
chr4_+_95129061 0.46 ENST00000354268.4
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr3_+_174158732 0.46 ENST00000434257.1
N-acetylated alpha-linked acidic dipeptidase-like 2
chr11_+_110225855 0.46 ENST00000526605.1
ENST00000526703.1
RP11-347E10.1
chr11_+_827248 0.45 ENST00000527089.1
ENST00000530183.1
EF-hand calcium binding domain 4A
chr15_-_52944231 0.45 ENST00000546305.2
family with sequence similarity 214, member A
chr3_+_171561127 0.45 ENST00000334567.5
ENST00000450693.1
transmembrane protein 212
chr5_-_114632307 0.45 ENST00000506442.1
ENST00000379611.5
coiled-coil domain containing 112
chr19_-_23433144 0.41 ENST00000418100.1
ENST00000597537.1
ENST00000597037.1
zinc finger protein 724, pseudogene
chrM_+_10464 0.41 ENST00000361335.1
mitochondrially encoded NADH dehydrogenase 4L
chr11_-_82745238 0.39 ENST00000531021.1
RAB30, member RAS oncogene family
chr12_-_10022735 0.39 ENST00000228438.2
C-type lectin domain family 2, member B
chr5_+_136070614 0.39 ENST00000502421.1
CTB-1I21.1
chr14_+_20187174 0.38 ENST00000557414.1
olfactory receptor, family 4, subfamily N, member 2
chrX_-_77395186 0.37 ENST00000341864.5
TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
chr12_-_68845417 0.36 ENST00000542875.1
RP11-81H14.2
chr19_-_22018966 0.36 ENST00000599906.1
ENST00000354959.4
zinc finger protein 43
chr2_+_187371440 0.36 ENST00000445547.1
zinc finger CCCH-type containing 15
chr12_-_25801478 0.34 ENST00000540106.1
ENST00000445693.1
ENST00000545543.1
ENST00000542224.1
intermediate filament tail domain containing 1
chr18_-_44500101 0.34 ENST00000589917.1
ENST00000587810.1
protein inhibitor of activated STAT, 2
chr7_+_111846741 0.31 ENST00000421043.1
ENST00000425229.1
ENST00000450657.1
zinc finger protein 277
chrX_+_108780062 0.31 ENST00000372106.1
nuclear transport factor 2-like export factor 2
chrM_+_10758 0.30 ENST00000361381.2
mitochondrially encoded NADH dehydrogenase 4
chrX_+_108780347 0.30 ENST00000372103.1
nuclear transport factor 2-like export factor 2
chr6_+_26183958 0.29 ENST00000356530.3
histone cluster 1, H2be
chrM_+_7586 0.29 ENST00000361739.1
mitochondrially encoded cytochrome c oxidase II
chr3_-_178976996 0.28 ENST00000485523.1
potassium large conductance calcium-activated channel, subfamily M beta member 3
chrX_+_102192200 0.28 ENST00000218249.5
RAB40A, member RAS oncogene family-like
chr12_-_91505608 0.27 ENST00000266718.4
lumican
chr4_-_70725856 0.27 ENST00000226444.3
sulfotransferase family 1E, estrogen-preferring, member 1
chr12_-_102591604 0.27 ENST00000329406.4
pro-melanin-concentrating hormone
chr19_-_23869999 0.26 ENST00000601935.1
ENST00000359788.4
ENST00000600313.1
ENST00000596211.1
ENST00000599168.1
zinc finger protein 675
chr16_-_70239683 0.25 ENST00000601706.1
Uncharacterized protein
chr3_+_177545563 0.25 ENST00000434309.1
RP11-91K9.1
chr7_-_64023441 0.25 ENST00000309683.6
zinc finger protein 680
chr4_-_112993808 0.24 ENST00000511219.1
RP11-269F21.3
chr11_-_89224638 0.24 ENST00000535633.1
ENST00000263317.4
NADPH oxidase 4
chr6_+_145118873 0.24 ENST00000432686.1
ENST00000417142.1
utrophin
chr10_-_14504093 0.24 ENST00000493380.1
ENST00000475141.2
FERM domain containing 4A
chr4_-_159080806 0.24 ENST00000590648.1
family with sequence similarity 198, member B
chr7_-_35013217 0.24 ENST00000446375.1
dpy-19-like 1 (C. elegans)
chr2_+_162101247 0.24 ENST00000439050.1
ENST00000436506.1
AC009299.3
chr20_+_32250079 0.23 ENST00000375222.3
chromosome 20 open reading frame 144
chr2_+_223536428 0.23 ENST00000446656.3
monoacylglycerol O-acyltransferase 1
chr1_+_203765437 0.23 ENST00000550078.1
zinc finger, BED-type containing 6
chr3_-_148939598 0.23 ENST00000455472.3
ceruloplasmin (ferroxidase)
chr6_-_56716686 0.23 ENST00000520645.1
dystonin
chr19_+_41281282 0.23 ENST00000263369.3
melanoma inhibitory activity
chr5_-_96518907 0.22 ENST00000508447.1
ENST00000283109.3
RIO kinase 2
chr13_-_25861530 0.22 ENST00000540661.1
myotubularin related protein 6
chr12_-_92536433 0.21 ENST00000551563.2
ENST00000546975.1
ENST00000549802.1
chromosome 12 open reading frame 79
chr9_+_82188077 0.21 ENST00000425506.1
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr10_+_69865866 0.21 ENST00000354393.2
myopalladin
chrM_+_8527 0.21 ENST00000361899.2
mitochondrially encoded ATP synthase 6
chr6_+_62284008 0.21 ENST00000544932.1
MT-RNR2-like 9 (pseudogene)
chr14_+_50291993 0.21 ENST00000595378.1
HCG1786899; PRO2610; Uncharacterized protein
chr7_-_34978980 0.21 ENST00000428054.1
dpy-19-like 1 (C. elegans)
chr12_+_69202795 0.21 ENST00000539479.1
ENST00000393415.3
ENST00000523991.1
ENST00000543323.1
ENST00000393416.2
MDM2 oncogene, E3 ubiquitin protein ligase
chr8_+_74271144 0.21 ENST00000519134.1
ENST00000518355.1
RP11-434I12.3
chr5_+_140557371 0.21 ENST00000239444.2
protocadherin beta 8
chr16_+_21608525 0.21 ENST00000567404.1
methyltransferase like 9
chr4_+_130017268 0.21 ENST00000425929.1
ENST00000508673.1
ENST00000508622.1
chromosome 4 open reading frame 33
chr9_-_69229650 0.21 ENST00000416428.1
COBW domain containing 6
chr11_-_85430204 0.20 ENST00000389958.3
ENST00000527794.1
synaptotagmin-like 2
chr4_-_69111401 0.20 ENST00000332644.5
transmembrane protease, serine 11B
chr8_+_32579321 0.20 ENST00000522402.1
neuregulin 1
chr8_+_52730143 0.20 ENST00000415643.1
Uncharacterized protein
chrM_+_8366 0.20 ENST00000361851.1
mitochondrially encoded ATP synthase 8
chr3_-_142166904 0.20 ENST00000264951.4
5'-3' exoribonuclease 1
chr7_+_64254793 0.19 ENST00000494380.1
ENST00000440155.2
ENST00000440598.1
ENST00000437743.1
zinc finger protein 138
chr19_-_21512115 0.19 ENST00000601295.1
zinc finger protein 708
chr13_-_48575401 0.19 ENST00000433022.1
ENST00000544100.1
succinate-CoA ligase, ADP-forming, beta subunit
chr2_+_172309634 0.19 ENST00000339506.3
DDB1 and CUL4 associated factor 17
chr11_-_58378759 0.19 ENST00000601906.1
Uncharacterized protein
chr6_-_121655593 0.18 ENST00000398212.2
TBC1 domain family, member 32
chr9_+_35042205 0.18 ENST00000312292.5
ENST00000378745.3
chromosome 9 open reading frame 131
chr2_-_201729284 0.18 ENST00000434813.2
CDC-like kinase 1
chr2_+_33683109 0.18 ENST00000437184.1
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr2_+_173955327 0.18 ENST00000422149.1
Mitogen-activated protein kinase kinase kinase MLT
chr3_-_165555200 0.18 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
butyrylcholinesterase
chr7_+_64126535 0.18 ENST00000344930.3
zinc finger protein 107
chr8_-_112248400 0.18 ENST00000519506.1
ENST00000522778.1
RP11-946L20.4
chr17_+_66539369 0.18 ENST00000600820.1
Uncharacterized protein; cDNA FLJ45097 fis, clone BRAWH3031054
chr19_-_7553889 0.18 ENST00000221480.1
peroxisomal biogenesis factor 11 gamma
chr8_+_86019382 0.18 ENST00000360375.3
leucine rich repeat and coiled-coil centrosomal protein 1
chr11_-_327537 0.18 ENST00000602735.1
interferon induced transmembrane protein 3
chr7_+_116660246 0.18 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
suppression of tumorigenicity 7
chr19_-_21512202 0.18 ENST00000356929.3
zinc finger protein 708
chr1_-_117021430 0.17 ENST00000423907.1
ENST00000434879.1
ENST00000443219.1
RP4-655J12.4
chr18_-_57027194 0.17 ENST00000251047.5
lectin, mannose-binding, 1
chr12_-_10588539 0.17 ENST00000381902.2
ENST00000381901.1
ENST00000539033.1
killer cell lectin-like receptor subfamily C, member 2
Uncharacterized protein
chr14_-_51027838 0.17 ENST00000555216.1
mitogen-activated protein kinase kinase kinase kinase 5
chr12_+_15154767 0.17 ENST00000542689.1
RP11-508P1.2
chr5_+_32788945 0.17 ENST00000326958.1
AC026703.1
chr10_+_32856764 0.17 ENST00000375030.2
ENST00000375028.3
Homo sapiens coiled-coil domain containing 7 (CCDC7), transcript variant 5, mRNA.
chr11_+_57365150 0.17 ENST00000457869.1
ENST00000340687.6
ENST00000378323.4
ENST00000378324.2
ENST00000403558.1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr1_-_243418344 0.17 ENST00000366542.1
centrosomal protein 170kDa
chr19_-_21950332 0.17 ENST00000598026.1
zinc finger protein 100
chr18_-_70211691 0.17 ENST00000269503.4
cerebellin 2 precursor
chr2_-_99279928 0.17 ENST00000414521.2
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr2_+_58134756 0.17 ENST00000435505.2
ENST00000417641.2
vaccinia related kinase 2
chr6_-_134861089 0.17 ENST00000606039.1
RP11-557H15.4
chr18_+_44526786 0.17 ENST00000245121.5
ENST00000356157.7
katanin p60 subunit A-like 2
chr7_+_111846643 0.17 ENST00000361822.3
zinc finger protein 277
chr2_+_179318295 0.17 ENST00000442710.1
deafness, autosomal recessive 59
chr7_+_7196565 0.17 ENST00000429911.1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr3_+_141596371 0.16 ENST00000495216.1
ATPase, Na+/K+ transporting, beta 3 polypeptide
chr6_+_122720681 0.16 ENST00000368455.4
ENST00000452194.1
heat shock transcription factor 2
chr6_-_109702885 0.16 ENST00000504373.1
CD164 molecule, sialomucin
chr3_-_101232019 0.16 ENST00000394095.2
ENST00000394091.1
ENST00000394094.2
ENST00000358203.3
ENST00000348610.3
ENST00000314261.7
SUMO1/sentrin specific peptidase 7
chr3_+_20081515 0.16 ENST00000263754.4
K(lysine) acetyltransferase 2B
chr14_+_39703084 0.16 ENST00000553728.1
cTAGE family member 5 isoform 4
chr11_-_10879572 0.16 ENST00000413761.2
zinc finger, BED-type containing 5
chrX_+_56644819 0.16 ENST00000446028.1
RP11-431N15.2
chr3_-_149510553 0.16 ENST00000462519.2
ENST00000446160.1
ENST00000383050.3
ankyrin repeat and ubiquitin domain containing 1
chr19_-_53426700 0.16 ENST00000596623.1
zinc finger protein 888
chrX_+_108779004 0.16 ENST00000218004.1
nuclear transport factor 2-like export factor 2
chr4_-_141348763 0.16 ENST00000509477.1
calmegin
chr19_+_55043977 0.16 ENST00000335056.3
killer cell immunoglobulin-like receptor, three domains, X1
chr2_+_118572226 0.16 ENST00000263239.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr10_+_94594351 0.16 ENST00000371552.4
exocyst complex component 6
chr17_+_52978185 0.16 ENST00000572405.1
ENST00000572158.1
ENST00000540336.1
ENST00000572298.1
ENST00000536554.1
ENST00000575333.1
ENST00000570499.1
ENST00000572576.1
target of myb1 (chicken)-like 1
chr21_-_43786634 0.16 ENST00000291527.2
trefoil factor 1
chr16_+_16434185 0.16 ENST00000524823.2
Protein PKD1P1
chr5_+_110073853 0.16 ENST00000513807.1
ENST00000509442.2
solute carrier family 25, member 46
chr2_-_61245363 0.15 ENST00000316752.6
pseudouridylate synthase 10
chr2_-_201753717 0.15 ENST00000409264.2
peptidylprolyl isomerase (cyclophilin)-like 3
chr2_-_201729393 0.15 ENST00000321356.4
CDC-like kinase 1
chr11_-_10879593 0.15 ENST00000528289.1
ENST00000432999.2
zinc finger, BED-type containing 5
chr12_+_20968608 0.15 ENST00000381541.3
ENST00000540229.1
ENST00000553473.1
ENST00000554957.1
Putative solute carrier organic anion transporter family member 1B7; Uncharacterized protein
solute carrier organic anion transporter family, member 1B3
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr6_-_106773291 0.15 ENST00000343245.3
autophagy related 5
chr6_-_113754604 0.15 ENST00000421737.1
RP1-124C6.1
chr2_-_238499131 0.15 ENST00000538644.1
RAB17, member RAS oncogene family
chr1_+_40942887 0.15 ENST00000372706.1
ZFP69 zinc finger protein
chr11_-_85430088 0.15 ENST00000533057.1
ENST00000533892.1
synaptotagmin-like 2
chr1_+_207943667 0.15 ENST00000462968.2
CD46 molecule, complement regulatory protein
chr5_-_57854070 0.15 ENST00000504333.1
Uncharacterized protein
chrM_+_10053 0.15 ENST00000361227.2
mitochondrially encoded NADH dehydrogenase 3
chr10_+_5238793 0.15 ENST00000263126.1
aldo-keto reductase family 1, member C4
chr6_-_26285737 0.15 ENST00000377727.1
ENST00000289352.1
histone cluster 1, H4h
chr12_-_76461249 0.15 ENST00000551524.1
nucleosome assembly protein 1-like 1
chr2_+_196440692 0.15 ENST00000458054.1
solute carrier family 39 (zinc transporter), member 10
chr19_+_21688366 0.14 ENST00000358491.4
ENST00000597078.1
zinc finger protein 429
chr1_+_186265399 0.14 ENST00000367486.3
ENST00000367484.3
ENST00000533951.1
ENST00000367482.4
ENST00000367483.4
ENST00000367485.4
ENST00000445192.2
proteoglycan 4
chr16_-_82045049 0.14 ENST00000532128.1
ENST00000328945.5
short chain dehydrogenase/reductase family 42E, member 1
chr10_+_13652047 0.14 ENST00000601460.1
Uncharacterized protein
chr4_+_102734967 0.14 ENST00000444316.2
B-cell scaffold protein with ankyrin repeats 1
chr11_-_85430356 0.14 ENST00000526999.1
synaptotagmin-like 2
chr17_+_58018269 0.14 ENST00000591035.1
Uncharacterized protein
chr12_-_10573149 0.14 ENST00000381904.2
ENST00000381903.2
ENST00000396439.2
killer cell lectin-like receptor subfamily C, member 3
chr13_+_32889605 0.14 ENST00000380152.3
ENST00000544455.1
ENST00000530893.2
breast cancer 2, early onset
chr16_-_46782221 0.14 ENST00000394809.4
myosin light chain kinase 3
chr12_-_110906027 0.14 ENST00000537466.2
ENST00000550974.1
ENST00000228827.3
GPN-loop GTPase 3
chr12_+_85430110 0.14 ENST00000393212.3
ENST00000393217.2
leucine-rich repeats and IQ motif containing 1
chr1_-_108231101 0.14 ENST00000544443.1
ENST00000415432.2
vav 3 guanine nucleotide exchange factor
chr6_-_10115007 0.14 ENST00000485268.1
orofacial cleft 1 candidate 1
chr3_+_44690211 0.14 ENST00000396056.2
ENST00000432115.2
ENST00000415571.2
ENST00000399560.2
ENST00000296092.3
ENST00000542250.1
ENST00000453164.1
zinc finger protein 35
chr10_+_91461337 0.14 ENST00000260753.4
ENST00000416354.1
ENST00000394289.2
ENST00000371728.3
kinesin family member 20B
chr6_-_108278456 0.14 ENST00000429168.1
SEC63 homolog (S. cerevisiae)
chr11_+_74303612 0.14 ENST00000527458.1
ENST00000532497.1
ENST00000530511.1
polymerase (DNA-directed), delta 3, accessory subunit
chr6_+_26440700 0.14 ENST00000494393.1
ENST00000482451.1
ENST00000244519.2
ENST00000339789.4
ENST00000471353.1
ENST00000361232.3
ENST00000487627.1
ENST00000496719.1
ENST00000490254.1
ENST00000487272.1
butyrophilin, subfamily 3, member A3
chr17_+_68164752 0.14 ENST00000535240.1
potassium inwardly-rectifying channel, subfamily J, member 2
chr19_+_55141861 0.13 ENST00000396327.3
ENST00000324602.7
ENST00000434867.2
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr12_+_69202975 0.13 ENST00000544561.1
ENST00000393410.1
ENST00000299252.4
ENST00000360430.2
ENST00000517852.1
ENST00000545204.1
ENST00000393413.3
ENST00000350057.5
ENST00000348801.2
ENST00000478070.1
MDM2 oncogene, E3 ubiquitin protein ligase
chr17_-_57229155 0.13 ENST00000584089.1
spindle and kinetochore associated complex subunit 2
chr6_-_150212029 0.13 ENST00000529948.1
ENST00000357183.4
ENST00000367363.3
retinoic acid early transcript 1E
chr9_-_21335240 0.13 ENST00000537938.1
kelch-like family member 9
chr11_+_327171 0.13 ENST00000534483.1
ENST00000524824.1
ENST00000531076.1
RP11-326C3.12
chr11_-_96123022 0.13 ENST00000542662.1
coiled-coil domain containing 82
chr9_-_99540328 0.13 ENST00000223428.4
ENST00000375231.1
ENST00000374641.3
zinc finger protein 510
chr6_-_114194483 0.13 ENST00000434296.2
RP1-249H1.4
chr2_-_162931052 0.13 ENST00000360534.3
dipeptidyl-peptidase 4
chr22_-_38480100 0.13 ENST00000427592.1
solute carrier family 16 (monocarboxylate transporter), member 8
chr3_-_32544900 0.13 ENST00000205636.3
CKLF-like MARVEL transmembrane domain containing 6
chr4_+_78804393 0.13 ENST00000502384.1
mitochondrial ribosomal protein L1
chr18_-_52626622 0.13 ENST00000591504.1
coiled-coil domain containing 68
chr3_+_141594966 0.13 ENST00000475483.1
ATPase, Na+/K+ transporting, beta 3 polypeptide
chr1_+_66797687 0.13 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
phosphodiesterase 4B, cAMP-specific
chr2_+_170440844 0.13 ENST00000260970.3
ENST00000433207.1
ENST00000409714.3
ENST00000462903.1
peptidylprolyl isomerase G (cyclophilin G)
chr17_+_52978156 0.13 ENST00000348161.4
target of myb1 (chicken)-like 1
chr5_-_75013193 0.13 ENST00000514838.2
ENST00000506164.1
ENST00000502826.1
ENST00000503835.1
ENST00000428202.2
ENST00000380475.2
POC5 centriolar protein
chr7_+_64254766 0.13 ENST00000307355.7
ENST00000359735.3
zinc finger protein 138
chr18_+_47088401 0.13 ENST00000261292.4
ENST00000427224.2
ENST00000580036.1
lipase, endothelial

Network of associatons between targets according to the STRING database.

First level regulatory network of SOX13_SOX12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.1 0.3 GO:0006711 estrogen catabolic process(GO:0006711)
0.1 0.7 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.1 0.2 GO:2001193 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.1 0.6 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.1 0.5 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.3 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.1 0.4 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.1 0.2 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 1.5 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 0.3 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.2 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.0 0.1 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.0 0.1 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.0 0.7 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.2 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.1 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.7 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:0010716 negative regulation of extracellular matrix disassembly(GO:0010716)
0.0 0.3 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.0 0.2 GO:0016267 O-glycan processing, core 1(GO:0016267)
0.0 0.2 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076) positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.4 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.1 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.2 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 0.2 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.0 0.1 GO:0050904 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) diapedesis(GO:0050904)
0.0 0.2 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.6 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 0.2 GO:1903436 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.2 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.0 0.2 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.0 0.1 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 0.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.1 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.1 GO:0042495 detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
0.0 0.1 GO:0010983 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.0 0.1 GO:1903615 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 0.3 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.0 0.1 GO:1904344 positive regulation of growth rate(GO:0040010) regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) regulation of small intestine smooth muscle contraction(GO:1904347) positive regulation of small intestine smooth muscle contraction(GO:1904349) gastric mucosal blood circulation(GO:1990768) small intestine smooth muscle contraction(GO:1990770)
0.0 0.1 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.1 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.1 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.1 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.2 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.1 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.0 0.1 GO:0035803 egg coat formation(GO:0035803)
0.0 0.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
0.0 0.1 GO:0061030 elastin metabolic process(GO:0051541) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.1 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.0 0.1 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.1 GO:2001202 negative regulation of transforming growth factor-beta secretion(GO:2001202)
0.0 1.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.0 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0 0.1 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.2 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:0071684 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.1 GO:0006789 bilirubin conjugation(GO:0006789)
0.0 0.1 GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.0 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.1 GO:0002456 T cell mediated immunity(GO:0002456)
0.0 0.0 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.0 GO:0035910 negative regulation of transcription by transcription factor localization(GO:0010621) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.0 0.0 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of fibrinolysis(GO:0051919)
0.0 0.1 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0060437 lung growth(GO:0060437)
0.0 0.0 GO:0003192 mitral valve formation(GO:0003192)
0.0 0.1 GO:2000371 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.0 0.1 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.3 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.0 GO:0090410 malonate catabolic process(GO:0090410)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0 0.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.2 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.5 GO:2000772 regulation of cellular senescence(GO:2000772)
0.0 0.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.1 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.2 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0089718 amino acid import across plasma membrane(GO:0089718)
0.0 0.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0031673 H zone(GO:0031673)
0.0 0.1 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.2 GO:0000125 PCAF complex(GO:0000125)
0.0 0.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.1 GO:0030687 preribosome(GO:0030684) preribosome, large subunit precursor(GO:0030687)
0.0 0.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 1.6 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.5 GO:0070938 contractile ring(GO:0070938)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.1 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.1 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124)
0.0 0.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.2 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 1.3 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.0 0.4 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.1 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0 0.1 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
0.0 0.2 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.1 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential(GO:0086057)
0.1 0.4 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 0.3 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.1 0.2 GO:0030109 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107) HLA-B specific inhibitory MHC class I receptor activity(GO:0030109) inhibitory MHC class I receptor activity(GO:0032396)
0.1 0.2 GO:0033265 choline binding(GO:0033265)
0.1 0.7 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.4 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.2 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263)
0.0 0.1 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.2 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.2 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.3 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.0 0.2 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.1 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
0.0 0.2 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.0 0.2 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.1 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.0 0.1 GO:0016608 growth hormone-releasing hormone activity(GO:0016608) ghrelin receptor binding(GO:0031768)
0.0 0.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.3 GO:0019826 oxygen sensor activity(GO:0019826)
0.0 0.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 1.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 1.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.5 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 0.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.1 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0 0.1 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.0 GO:0090409 malonyl-CoA synthetase activity(GO:0090409)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0052828 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.0 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.0 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.0 0.1 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.8 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.7 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.1 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.3 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.1 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation