Project
A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
Navigation
Downloads
Results for SIX1_SIX3_SIX2
Z-value: 0.83
Motif logo
Transcription factors associated with SIX1_SIX3_SIX2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| SIX1 | hg19_v2_chr14_-_61124977_61125037 | 0.86 | 3.0e-02 | Click! |
| SIX3 | hg19_v2_chr2_+_45168875_45168916 | 0.41 | 4.2e-01 | Click! |
| SIX2 | hg19_v2_chr2_-_45236540_45236577 | 0.06 | 9.1e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr16_-_28550320 Show fit | 0.89 |
ENST00000395641.2
|
nuclear protein, transcriptional regulator, 1 |
|
| chr3_+_42850959 Show fit | 0.72 |
ENST00000442925.1
ENST00000422265.1 ENST00000497921.1 ENST00000426937.1 |
atypical chemokine receptor 2 KRAB box domain containing 1 |
|
| chr7_+_139025875 Show fit | 0.69 |
ENST00000297534.6
|
chromosome 7 open reading frame 55 |
|
| chr14_+_91709103 Show fit | 0.66 |
ENST00000553725.1
|
HCG1816139; Uncharacterized protein |
|
| chr1_-_179457805 Show fit | 0.51 |
ENST00000600581.1
|
Uncharacterized protein |
|
| chr16_-_28550348 Show fit | 0.49 |
ENST00000324873.6
|
nuclear protein, transcriptional regulator, 1 |
|
| chr3_+_70048881 Show fit | 0.46 |
ENST00000483525.1
|
RP11-460N16.1 |
|
| chr13_-_46679144 Show fit | 0.39 |
ENST00000181383.4
|
carboxypeptidase B2 (plasma) |
|
| chr7_-_34978980 Show fit | 0.32 |
ENST00000428054.1
|
dpy-19-like 1 (C. elegans) |
|
| chr16_+_58010339 Show fit | 0.32 |
ENST00000290871.5
ENST00000441824.2 |
testis, prostate and placenta expressed |
Network of associatons between targets according to the STRING database.
First level regulatory network of SIX1_SIX3_SIX2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.4 | GO:2000194 | regulation of female gonad development(GO:2000194) |
| 0.1 | 0.7 | GO:0046874 | quinolinate metabolic process(GO:0046874) |
| 0.1 | 0.6 | GO:0019264 | glycine biosynthetic process from serine(GO:0019264) |
| 0.0 | 0.5 | GO:0090286 | cytoskeletal anchoring at nuclear membrane(GO:0090286) |
| 0.1 | 0.4 | GO:0003331 | regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331) |
| 0.0 | 0.3 | GO:0018211 | protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406) |
| 0.0 | 0.3 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.0 | 0.3 | GO:0031167 | rRNA methylation(GO:0031167) |
| 0.0 | 0.3 | GO:0070129 | regulation of mitochondrial translation(GO:0070129) |
| 0.1 | 0.2 | GO:0019287 | isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.6 | GO:0070552 | BRISC complex(GO:0070552) |
| 0.0 | 0.5 | GO:0034992 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.0 | 0.2 | GO:0097169 | AIM2 inflammasome complex(GO:0097169) |
| 0.0 | 0.2 | GO:0032437 | cuticular plate(GO:0032437) |
| 0.0 | 0.2 | GO:0071203 | WASH complex(GO:0071203) |
| 0.0 | 0.2 | GO:0005688 | U6 snRNP(GO:0005688) |
| 0.0 | 0.2 | GO:0030991 | intraciliary transport particle A(GO:0030991) |
| 0.0 | 0.1 | GO:0097524 | sperm plasma membrane(GO:0097524) |
| 0.0 | 0.1 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.0 | 0.1 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.7 | GO:0019957 | C-C chemokine binding(GO:0019957) |
| 0.1 | 0.6 | GO:0004372 | glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) |
| 0.0 | 0.5 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
| 0.0 | 0.4 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.1 | 0.3 | GO:0000179 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) |
| 0.0 | 0.3 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 0.0 | 0.3 | GO:0043495 | protein anchor(GO:0043495) |
| 0.0 | 0.2 | GO:0004514 | nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514) |
| 0.0 | 0.2 | GO:0004873 | asialoglycoprotein receptor activity(GO:0004873) |
| 0.0 | 0.2 | GO:0015181 | arginine transmembrane transporter activity(GO:0015181) |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.0 | 0.2 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |