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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for RUNX1_RUNX2

Z-value: 1.34

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Transcription factors associated with RUNX1_RUNX2

Gene Symbol Gene ID Gene Info
ENSG00000159216.14 RUNX family transcription factor 1
ENSG00000124813.16 RUNX family transcription factor 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RUNX1hg19_v2_chr21_-_36259445_362595190.843.6e-02Click!
RUNX2hg19_v2_chr6_+_45296391_45296464-0.681.3e-01Click!

Activity profile of RUNX1_RUNX2 motif

Sorted Z-values of RUNX1_RUNX2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr21_-_36421401 0.94 ENST00000486278.2
runt-related transcription factor 1
chr11_-_1606513 0.86 ENST00000382171.2
keratin associated protein 5-1
chr6_-_152623231 0.80 ENST00000540663.1
ENST00000537033.1
spectrin repeat containing, nuclear envelope 1
chr12_-_58145889 0.78 ENST00000547853.1
cyclin-dependent kinase 4
chr17_+_73629500 0.78 ENST00000375215.3
small integral membrane protein 5
chr17_+_40274756 0.72 ENST00000355067.3
heat shock protein, alpha-crystallin-related, B9
chr17_+_73780852 0.71 ENST00000589666.1
unkempt family zinc finger
chr11_+_62475130 0.69 ENST00000294117.5
guanine nucleotide binding protein (G protein), gamma 3
chr1_+_179051160 0.67 ENST00000367625.4
ENST00000352445.6
torsin family 3, member A
chr14_+_100531615 0.65 ENST00000392920.3
Enah/Vasp-like
chr17_+_76037081 0.64 ENST00000588549.1
trinucleotide repeat containing 6C
chr15_+_67390920 0.62 ENST00000559092.1
ENST00000560175.1
SMAD family member 3
chr17_+_75316336 0.59 ENST00000591934.1
septin 9
chr1_+_23695680 0.59 ENST00000454117.1
ENST00000335648.3
ENST00000518821.1
ENST00000437367.2
chromosome 1 open reading frame 213
chr1_-_147632428 0.59 ENST00000599640.1
Uncharacterized protein FLJ46360
chr4_-_84035905 0.57 ENST00000311507.4
placenta-specific 8
chr7_+_134832808 0.56 ENST00000275767.3
transmembrane protein 140
chr1_+_156211753 0.52 ENST00000368272.4
bone gamma-carboxyglutamate (gla) protein
chr1_-_150978953 0.52 ENST00000493834.2
family with sequence similarity 63, member A
chr15_+_58724184 0.51 ENST00000433326.2
lipase, hepatic
chrX_-_1331527 0.50 ENST00000381567.3
ENST00000381566.1
ENST00000400841.2
cytokine receptor-like factor 2
chr11_+_826136 0.50 ENST00000528315.1
ENST00000533803.1
EF-hand calcium binding domain 4A
chr5_-_138861926 0.50 ENST00000510817.1
transmembrane protein 173
chr11_+_6411636 0.48 ENST00000299397.3
ENST00000356761.2
ENST00000342245.4
sphingomyelin phosphodiesterase 1, acid lysosomal
chr16_+_72088376 0.47 ENST00000570083.1
ENST00000355906.5
ENST00000398131.2
ENST00000569639.1
ENST00000564499.1
ENST00000357763.4
ENST00000562526.1
ENST00000565574.1
ENST00000568417.2
ENST00000356967.5
haptoglobin
haptoglobin-related protein
chr20_-_1600642 0.46 ENST00000381603.3
ENST00000381605.4
ENST00000279477.7
ENST00000568365.1
ENST00000564763.1
signal-regulatory protein beta 1
Uncharacterized protein
chr22_+_22988816 0.46 ENST00000480559.1
ENST00000448514.1
gamma-glutamyltransferase light chain 2
chr17_+_79008940 0.45 ENST00000392411.3
ENST00000575989.1
ENST00000321280.7
ENST00000428708.2
ENST00000575712.1
ENST00000575245.1
ENST00000435091.3
ENST00000321300.6
BAI1-associated protein 2
chr1_-_21948906 0.44 ENST00000374761.2
ENST00000599760.1
RAP1 GTPase activating protein
chr3_+_50284321 0.44 ENST00000451956.1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chrX_-_106960285 0.43 ENST00000503515.1
ENST00000372397.2
TSC22 domain family, member 3
chr1_-_145589424 0.43 ENST00000334513.5
nudix (nucleoside diphosphate linked moiety X)-type motif 17
chr20_+_61924532 0.43 ENST00000358894.6
ENST00000326996.6
ENST00000435874.1
collagen, type XX, alpha 1
chr6_+_24126350 0.42 ENST00000378491.4
ENST00000378478.1
ENST00000378477.2
neurensin 1
chr2_-_61389168 0.41 ENST00000607743.1
ENST00000605902.1
RP11-493E12.1
chr19_+_56989485 0.41 ENST00000585445.1
ENST00000586091.1
ENST00000594783.1
ENST00000592146.1
ENST00000588158.1
ENST00000299997.4
ENST00000591797.1
ZNF667 antisense RNA 1 (head to head)
chr1_-_1690014 0.41 ENST00000400922.2
ENST00000342348.5
NAD kinase
chr19_-_55895966 0.41 ENST00000444469.3
transmembrane protein 238
chr19_+_36134528 0.40 ENST00000591135.1
ets variant 2
chr2_-_27531313 0.40 ENST00000296099.2
urocortin
chr11_+_6411670 0.40 ENST00000530395.1
ENST00000527275.1
sphingomyelin phosphodiesterase 1, acid lysosomal
chrX_-_128788914 0.40 ENST00000429967.1
ENST00000307484.6
apelin
chr1_+_149239529 0.39 ENST00000457216.2
RP11-403I13.4
chr2_+_95537248 0.39 ENST00000427593.2
tektin 4
chr1_-_39395165 0.39 ENST00000372985.3
rhomboid, veinlet-like 2 (Drosophila)
chr17_-_3495644 0.38 ENST00000310522.5
ENST00000425167.2
ENST00000576351.1
transient receptor potential cation channel, subfamily V, member 1
chr1_+_174843548 0.38 ENST00000478442.1
ENST00000465412.1
RAB GTPase activating protein 1-like
chr1_-_168464875 0.38 ENST00000422253.1
RP5-968D22.3
chr7_+_100551239 0.38 ENST00000319509.7
mucin 3A, cell surface associated
chr12_+_57828521 0.38 ENST00000309668.2
inhibin, beta C
chr5_+_145316120 0.37 ENST00000359120.4
SH3 domain containing ring finger 2
chr21_-_36421535 0.37 ENST00000416754.1
ENST00000437180.1
ENST00000455571.1
runt-related transcription factor 1
chr21_-_33957805 0.36 ENST00000300258.3
ENST00000472557.1
t-complex 10-like
chr8_-_130587237 0.36 ENST00000520048.1
coiled-coil domain containing 26
chr1_+_236557569 0.36 ENST00000334232.4
EDAR-associated death domain
chr5_+_667759 0.36 ENST00000594226.1
Uncharacterized protein
chr14_-_92247032 0.36 ENST00000556661.1
ENST00000553676.1
ENST00000554560.1
catsper channel auxiliary subunit beta
chr9_+_131902346 0.36 ENST00000432124.1
ENST00000435305.1
protein phosphatase 2A activator, regulatory subunit 4
chr2_+_177001685 0.36 ENST00000432796.2
homeobox D3
chr17_+_50939459 0.35 ENST00000412360.1
Uncharacterized protein
chr3_+_156799587 0.35 ENST00000469196.1
RP11-6F2.5
chr19_-_39303576 0.35 ENST00000594209.1
lectin, galactoside-binding, soluble, 4
chr11_+_115498761 0.35 ENST00000424313.2
AP000997.1
chr6_+_159071015 0.35 ENST00000360448.3
synaptotagmin-like 3
chr17_-_43025005 0.35 ENST00000587309.1
ENST00000593135.1
ENST00000339151.4
kinesin family member 18B
chrX_-_100129128 0.35 ENST00000372960.4
ENST00000372964.1
ENST00000217885.5
NADPH oxidase 1
chr16_+_84801852 0.34 ENST00000569925.1
ENST00000567526.1
ubiquitin specific peptidase 10
chr19_+_36630961 0.34 ENST00000587718.1
ENST00000592483.1
ENST00000590874.1
ENST00000588815.1
calpain, small subunit 1
chr7_-_7782204 0.34 ENST00000418534.2
AC007161.5
chr1_+_39876151 0.34 ENST00000530275.1
KIAA0754
chr10_-_15139318 0.34 ENST00000378207.3
chromosome 10 open reading frame 111
chr1_-_157014865 0.34 ENST00000361409.2
Rho guanine nucleotide exchange factor (GEF) 11
chr14_+_24674926 0.34 ENST00000339917.5
ENST00000556621.1
ENST00000287913.6
ENST00000428351.2
ENST00000555092.1
testis-specific serine kinase 4
chr6_+_157099036 0.33 ENST00000350026.5
ENST00000346085.5
ENST00000367148.1
ENST00000275248.4
AT rich interactive domain 1B (SWI1-like)
chr11_+_2923423 0.33 ENST00000312221.5
solute carrier family 22, member 18
chr1_+_179050512 0.33 ENST00000367627.3
torsin family 3, member A
chr16_-_4850471 0.33 ENST00000592019.1
ENST00000586153.1
rogdi homolog (Drosophila)
chr14_+_77244349 0.33 ENST00000554743.1
vasohibin 1
chr2_+_30455016 0.33 ENST00000401506.1
ENST00000407930.2
limb bud and heart development
chr16_+_2570340 0.33 ENST00000568263.1
ENST00000293971.6
ENST00000302956.4
ENST00000413459.3
ENST00000566706.1
ENST00000569879.1
amidohydrolase domain containing 2
chr17_+_73996987 0.33 ENST00000588812.1
ENST00000448471.1
cyclin-dependent kinase 3
chr19_-_47291843 0.32 ENST00000542575.2
solute carrier family 1 (neutral amino acid transporter), member 5
chr12_-_121972556 0.32 ENST00000545022.1
lysine (K)-specific demethylase 2B
chr1_-_204165610 0.32 ENST00000367194.4
KiSS-1 metastasis-suppressor
chrX_-_154376044 0.32 ENST00000362018.2
mature T-cell proliferation 1
chr17_-_1531635 0.32 ENST00000571650.1
solute carrier family 43 (amino acid system L transporter), member 2
chr17_+_79935418 0.32 ENST00000306729.7
ENST00000306739.4
alveolar soft part sarcoma chromosome region, candidate 1
chrX_+_22056165 0.32 ENST00000535894.1
phosphate regulating endopeptidase homolog, X-linked
chr1_-_206945830 0.32 ENST00000423557.1
interleukin 10
chr8_+_55471630 0.31 ENST00000522001.1
RP11-53M11.3
chr2_+_242752474 0.31 ENST00000435934.1
ENST00000435894.1
ENST00000426032.1
ENST00000420288.1
sialidase 4
chr16_+_81772633 0.31 ENST00000566191.1
ENST00000565272.1
ENST00000563954.1
ENST00000565054.1
RP11-960L18.1
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr16_-_67867749 0.31 ENST00000566758.1
ENST00000445712.2
ENST00000219172.3
ENST00000564817.1
centromere protein T
chrX_+_155227246 0.30 ENST00000244174.5
ENST00000424344.3
interleukin 9 receptor
chr15_+_89631647 0.30 ENST00000569550.1
ENST00000565066.1
ENST00000565973.1
abhydrolase domain containing 2
chr19_+_42580274 0.30 ENST00000359044.4
zinc finger protein 574
chr1_-_233431458 0.30 ENST00000258229.9
ENST00000430153.1
pecanex-like 2 (Drosophila)
chr11_+_86502085 0.30 ENST00000527521.1
protease, serine, 23
chr1_+_200863949 0.30 ENST00000413687.2
chromosome 1 open reading frame 106
chr2_+_101591314 0.30 ENST00000450763.1
neuronal PAS domain protein 2
chr17_+_75447326 0.30 ENST00000591088.1
septin 9
chr4_+_89300158 0.30 ENST00000502870.1
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr12_-_58027138 0.30 ENST00000341156.4
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr1_+_11333546 0.30 ENST00000376804.2
UbiA prenyltransferase domain containing 1
chr1_+_221051699 0.30 ENST00000366903.6
H2.0-like homeobox
chr15_-_33447055 0.30 ENST00000559047.1
ENST00000561249.1
formin 1
chr17_-_42188598 0.30 ENST00000591714.1
histone deacetylase 5
chr11_+_117070904 0.30 ENST00000529792.1
transgelin
chrX_-_49460578 0.30 ENST00000376150.3
P antigen family, member 1 (prostate associated)
chr16_+_2106134 0.30 ENST00000467949.1
tuberous sclerosis 2
chr11_-_1771797 0.30 ENST00000340134.4
interferon induced transmembrane protein 10
chr16_+_29674540 0.29 ENST00000436527.1
ENST00000360121.3
ENST00000449759.1
sialophorin
quinolinate phosphoribosyltransferase
chr16_-_11350036 0.29 ENST00000332029.2
suppressor of cytokine signaling 1
chr7_+_76054224 0.29 ENST00000394857.3
zona pellucida glycoprotein 3 (sperm receptor)
chr6_-_31514516 0.29 ENST00000303892.5
ENST00000483251.1
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr17_+_19281034 0.29 ENST00000308406.5
ENST00000299612.7
mitogen-activated protein kinase 7
chr11_-_65548265 0.29 ENST00000532090.2
adaptor-related protein complex 5, beta 1 subunit
chr19_+_48969094 0.29 ENST00000595676.1
Uncharacterized protein
chr2_+_239335449 0.29 ENST00000264607.4
ankyrin repeat and SOCS box containing 1
chr22_-_21580582 0.29 ENST00000424627.1
gamma-glutamyltransferase 2
chr12_+_25205446 0.29 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
lymphoid-restricted membrane protein
chr2_-_152118276 0.29 ENST00000409092.1
RNA binding motif protein 43
chr12_+_47610315 0.28 ENST00000548348.1
ENST00000549500.1
PC-esterase domain containing 1B
chr8_-_146078376 0.28 ENST00000533270.1
ENST00000305103.3
ENST00000402718.3
COMM domain containing 5
chr11_+_2923499 0.28 ENST00000449793.2
solute carrier family 22, member 18
chr12_-_53574376 0.28 ENST00000267085.4
ENST00000379850.3
ENST00000379846.1
ENST00000424990.1
cysteine sulfinic acid decarboxylase
chr11_-_116968987 0.28 ENST00000434315.2
ENST00000292055.4
ENST00000375288.1
ENST00000542607.1
ENST00000445177.1
ENST00000375300.1
ENST00000446921.2
SIK family kinase 3
chr10_+_123951957 0.28 ENST00000514539.1
transforming, acidic coiled-coil containing protein 2
chr19_+_41882598 0.28 ENST00000447302.2
ENST00000544232.1
ENST00000542945.1
ENST00000540732.1
transmembrane protein 91
2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial; Uncharacterized protein
chr16_+_89979826 0.28 ENST00000555427.1
melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
chr12_-_54121212 0.28 ENST00000548263.1
ENST00000430117.2
ENST00000550804.1
ENST00000549173.1
ENST00000551900.1
ENST00000546619.1
ENST00000548177.1
ENST00000549349.1
calcium binding and coiled-coil domain 1
chr1_-_25291475 0.28 ENST00000338888.3
ENST00000399916.1
runt-related transcription factor 3
chr12_-_31158902 0.28 ENST00000544329.1
ENST00000418254.2
ENST00000222396.5
RP11-551L14.4
chr7_+_97910981 0.27 ENST00000297290.3
brain protein I3
chr22_+_44464923 0.27 ENST00000404989.1
parvin, beta
chr6_+_31515337 0.27 ENST00000376148.4
ENST00000376145.4
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr12_+_122516626 0.27 ENST00000319080.7
MLX interacting protein
chr2_+_132044330 0.27 ENST00000416266.1
cytochrome P450, family 4, subfamily F, polypeptide 31, pseudogene
chr16_+_28505955 0.27 ENST00000564831.1
ENST00000328423.5
ENST00000431282.1
apolipoprotein B receptor
chr1_+_3816936 0.27 ENST00000413332.1
ENST00000442673.1
ENST00000439488.1
long intergenic non-protein coding RNA 1134
chr7_+_139025875 0.27 ENST00000297534.6
chromosome 7 open reading frame 55
chr1_-_150980828 0.27 ENST00000361936.5
ENST00000361738.6
family with sequence similarity 63, member A
chr12_-_10601963 0.27 ENST00000543893.1
killer cell lectin-like receptor subfamily C, member 1
chrX_-_19688475 0.27 ENST00000541422.1
SH3-domain kinase binding protein 1
chr9_+_131902283 0.27 ENST00000436883.1
ENST00000414510.1
protein phosphatase 2A activator, regulatory subunit 4
chr11_+_65337901 0.26 ENST00000309328.3
ENST00000531405.1
ENST00000527920.1
ENST00000526877.1
ENST00000533115.1
ENST00000526433.1
Sjogren syndrome/scleroderma autoantigen 1
chr12_-_49463753 0.26 ENST00000301068.6
Ras homolog enriched in brain like 1
chrX_+_153046456 0.26 ENST00000393786.3
ENST00000370104.1
ENST00000370108.3
ENST00000370101.3
ENST00000430541.1
ENST00000370100.1
SRSF protein kinase 3
chr4_-_187517928 0.26 ENST00000512772.1
FAT atypical cadherin 1
chr4_-_82393052 0.26 ENST00000335927.7
ENST00000504863.1
ENST00000264400.2
RasGEF domain family, member 1B
chr2_-_217236750 0.26 ENST00000273067.4
membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase
chr11_+_65647280 0.26 ENST00000307886.3
ENST00000528419.1
ENST00000526034.1
cathepsin W
chr9_-_35563896 0.26 ENST00000399742.2
family with sequence similarity 166, member B
chr19_-_51875894 0.26 ENST00000600427.1
ENST00000595217.1
ENST00000221978.5
natural killer cell group 7 sequence
chr18_+_61575200 0.26 ENST00000238508.3
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr12_+_116985896 0.26 ENST00000547114.1
RP11-809C9.2
chrX_+_155227371 0.26 ENST00000369423.2
ENST00000540897.1
interleukin 9 receptor
chr1_+_155290677 0.25 ENST00000368354.3
ENST00000368352.5
RUN and SH3 domain containing 1
chr2_+_136499287 0.25 ENST00000415164.1
UBX domain protein 4
chr4_+_88896819 0.25 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
secreted phosphoprotein 1
chr16_+_20911174 0.25 ENST00000568663.1
LYR motif containing 1
chr6_+_36646435 0.25 ENST00000244741.5
ENST00000405375.1
ENST00000373711.2
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr1_+_145726886 0.25 ENST00000443667.1
PDZ domain containing 1
chr17_+_41994576 0.25 ENST00000588043.2
family with sequence similarity 215, member A (non-protein coding)
chr16_+_28875126 0.25 ENST00000359285.5
ENST00000538342.1
SH2B adaptor protein 1
chr6_+_45296048 0.25 ENST00000465038.2
ENST00000352853.5
ENST00000541979.1
ENST00000371438.1
runt-related transcription factor 2
chr6_+_31514622 0.25 ENST00000376146.4
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr1_+_44889697 0.25 ENST00000443020.2
ring finger protein 220
chr1_+_37947257 0.25 ENST00000471012.1
zinc finger CCCH-type containing 12A
chr17_+_67590125 0.25 ENST00000591334.1
AC003051.1
chr19_+_13988061 0.25 ENST00000339133.5
ENST00000397555.2
nanos homolog 3 (Drosophila)
chr17_-_18160584 0.25 ENST00000581349.1
ENST00000473425.2
flightless I homolog (Drosophila)
chr16_-_31100284 0.25 ENST00000280606.6
protease, serine, 53
chr17_+_25958174 0.25 ENST00000313648.6
ENST00000577392.1
ENST00000584661.1
ENST00000413914.2
lectin, galactoside-binding, soluble, 9
chr17_-_1532106 0.24 ENST00000301335.5
ENST00000382147.4
solute carrier family 43 (amino acid system L transporter), member 2
chr1_+_149858461 0.24 ENST00000331380.2
histone cluster 2, H2ac
chr2_+_201980827 0.24 ENST00000309955.3
ENST00000443227.1
ENST00000341222.6
ENST00000355558.4
ENST00000340870.5
ENST00000341582.6
CASP8 and FADD-like apoptosis regulator
chr5_+_149877440 0.24 ENST00000518299.1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr18_-_3247084 0.24 ENST00000609924.1
RP13-270P17.3
chr16_+_14280742 0.24 ENST00000341243.5
MKL/myocardin-like 2
chr12_-_54121261 0.24 ENST00000549784.1
ENST00000262059.4
calcium binding and coiled-coil domain 1
chr9_+_139738867 0.24 ENST00000436881.1
chromosome 9 open reading frame 172
chr20_+_62492566 0.24 ENST00000369916.3
abhydrolase domain containing 16B
chr1_-_179112173 0.24 ENST00000408940.3
ENST00000504405.1
c-abl oncogene 2, non-receptor tyrosine kinase
chr17_-_1090599 0.24 ENST00000544583.2
active BCR-related
chr16_+_14280564 0.24 ENST00000572567.1
MKL/myocardin-like 2
chr8_+_39806685 0.24 ENST00000389060.4
indoleamine 2,3-dioxygenase 2
chr1_+_152486950 0.23 ENST00000368790.3
cysteine-rich C-terminal 1
chr11_+_36397528 0.23 ENST00000311599.5
ENST00000378867.3
proline rich 5 like
chr6_+_75994755 0.23 ENST00000607799.1
RP1-234P15.4
chr17_-_67057047 0.23 ENST00000495634.1
ENST00000453985.2
ENST00000585714.1
ATP-binding cassette, sub-family A (ABC1), member 9
chr5_-_159766528 0.23 ENST00000505287.2
cyclin J-like
chr6_+_116782527 0.23 ENST00000368606.3
ENST00000368605.1
family with sequence similarity 26, member F
chr16_+_8715536 0.23 ENST00000563958.1
ENST00000381920.3
ENST00000564554.1
methyltransferase like 22
chr6_+_158733692 0.23 ENST00000367094.2
ENST00000367097.3
tubby like protein 4
chr11_-_59633951 0.23 ENST00000257264.3
transcobalamin I (vitamin B12 binding protein, R binder family)
chr20_-_45530365 0.23 ENST00000414085.1
RP11-323C15.2
chr12_-_120687948 0.23 ENST00000458477.2
paxillin
chr22_-_31688381 0.23 ENST00000487265.2
phosphoinositide-3-kinase interacting protein 1
chr17_+_1633755 0.23 ENST00000545662.1
WD repeat domain 81

Network of associatons between targets according to the STRING database.

First level regulatory network of RUNX1_RUNX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.1 0.4 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.1 0.6 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.1 0.5 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.1 0.4 GO:0060796 regulation of transcription involved in primary germ layer cell fate commitment(GO:0060796)
0.1 0.4 GO:2000987 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.1 0.1 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.1 1.0 GO:0023021 termination of signal transduction(GO:0023021)
0.1 0.4 GO:0070377 regulation of ERK5 cascade(GO:0070376) negative regulation of ERK5 cascade(GO:0070377)
0.1 0.8 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.4 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.1 0.5 GO:0033594 response to hydroxyisoflavone(GO:0033594)
0.1 0.4 GO:0042412 taurine biosynthetic process(GO:0042412)
0.1 0.3 GO:0019732 antifungal humoral response(GO:0019732)
0.1 0.3 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.1 0.4 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 0.4 GO:0019046 release from viral latency(GO:0019046)
0.1 0.4 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.1 0.1 GO:0014839 myoblast migration involved in skeletal muscle regeneration(GO:0014839)
0.1 1.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.1 0.4 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.3 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.1 0.3 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.1 0.3 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.1 0.9 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.2 GO:1902955 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.3 GO:0002316 follicular B cell differentiation(GO:0002316)
0.1 0.2 GO:1990051 activation of protein kinase C activity(GO:1990051)
0.1 0.4 GO:0015878 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887)
0.1 0.8 GO:0030259 lipid glycosylation(GO:0030259)
0.1 0.6 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.7 GO:0046618 drug export(GO:0046618)
0.1 0.3 GO:0090345 cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.1 0.6 GO:0071104 response to interleukin-9(GO:0071104)
0.1 0.3 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1 0.5 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
0.1 0.2 GO:0021817 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473) nuclear migration along microfilament(GO:0031022)
0.1 0.3 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.1 0.2 GO:0050955 thermoception(GO:0050955)
0.1 1.0 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.2 GO:0002266 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.1 0.2 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.1 0.5 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.1 0.2 GO:0032581 ER-dependent peroxisome organization(GO:0032581)
0.1 0.8 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 0.2 GO:0014734 skeletal muscle hypertrophy(GO:0014734) regulation of skeletal muscle hypertrophy(GO:1904204)
0.1 0.5 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 0.5 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.1 0.3 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 0.3 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.1 1.0 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.1 0.2 GO:0071105 response to interleukin-11(GO:0071105) cellular response to interleukin-11(GO:0071348)
0.1 0.3 GO:2000035 regulation of stem cell division(GO:2000035)
0.1 0.2 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.1 0.2 GO:0036269 swimming behavior(GO:0036269)
0.1 0.3 GO:1904383 response to sodium phosphate(GO:1904383)
0.1 0.2 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.1 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.5 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372) phosphatidylcholine catabolic process(GO:0034638)
0.1 0.3 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.3 GO:0009233 menaquinone metabolic process(GO:0009233)
0.0 0.2 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.0 GO:0034136 negative regulation of toll-like receptor 2 signaling pathway(GO:0034136)
0.0 0.5 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.4 GO:0070269 pyroptosis(GO:0070269)
0.0 0.1 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.0 0.4 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.1 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.1 GO:0061110 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.2 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.0 0.1 GO:0032903 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.3 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.0 0.2 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0 0.4 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.0 0.1 GO:0048003 synaptic vesicle recycling via endosome(GO:0036466) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.2 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.0 0.5 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.2 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.2 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.0 0.3 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.4 GO:0035524 L-alanine transport(GO:0015808) proline transmembrane transport(GO:0035524)
0.0 0.2 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0 0.5 GO:0006477 protein sulfation(GO:0006477)
0.0 0.7 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.3 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.1 GO:0072244 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
0.0 0.2 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.2 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 0.3 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.0 GO:0034371 chylomicron remodeling(GO:0034371)
0.0 0.1 GO:0002590 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.0 0.1 GO:0002818 intracellular defense response(GO:0002818)
0.0 0.8 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.1 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.4 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.1 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.0 0.3 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.4 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.2 GO:0001555 oocyte growth(GO:0001555)
0.0 0.3 GO:0060313 negative regulation of blood vessel remodeling(GO:0060313)
0.0 0.1 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.2 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.1 GO:0072387 flavin adenine dinucleotide metabolic process(GO:0072387)
0.0 0.1 GO:0016999 antibiotic metabolic process(GO:0016999)
0.0 0.2 GO:0098502 DNA dephosphorylation(GO:0098502)
0.0 0.2 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.1 GO:0002884 negative regulation of type IV hypersensitivity(GO:0001808) negative regulation of hypersensitivity(GO:0002884)
0.0 0.1 GO:1900535 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.0 0.2 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.1 GO:0060345 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.0 0.3 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.0 0.1 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
0.0 0.1 GO:0002432 granuloma formation(GO:0002432)
0.0 0.1 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
0.0 0.6 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.0 0.2 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.6 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.2 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.0 0.4 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.1 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.0 1.1 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.1 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.1 GO:0060032 notochord regression(GO:0060032)
0.0 0.3 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.2 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0060381 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.0 0.2 GO:0060481 lung goblet cell differentiation(GO:0060480) lobar bronchus epithelium development(GO:0060481)
0.0 0.1 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.2 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.4 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.2 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.0 0.6 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.0 GO:0043132 NAD transport(GO:0043132)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.1 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.1 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.1 GO:2000329 peptidyl-lysine oxidation(GO:0018057) negative regulation of T-helper 17 cell lineage commitment(GO:2000329)
0.0 0.2 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.0 0.2 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.1 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.0 0.2 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.0 0.1 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.5 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.2 GO:0003418 growth plate cartilage chondrocyte differentiation(GO:0003418)
0.0 0.1 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 0.1 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.2 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.2 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0 0.2 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.1 GO:0045684 positive regulation of epidermis development(GO:0045684)
0.0 0.1 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.5 GO:0033160 positive regulation of protein import into nucleus, translocation(GO:0033160)
0.0 0.2 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.2 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.1 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.2 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.6 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.3 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.3 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.5 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.1 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.0 0.1 GO:1901291 negative regulation of double-strand break repair via single-strand annealing(GO:1901291)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.0 0.1 GO:0032053 ciliary basal body organization(GO:0032053)
0.0 0.3 GO:0002860 positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
0.0 0.1 GO:0072287 metanephric distal tubule morphogenesis(GO:0072287)
0.0 0.2 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.0 0.3 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.1 GO:0046709 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.0 0.2 GO:2001033 negative regulation of double-strand break repair via nonhomologous end joining(GO:2001033)
0.0 0.2 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:0015961 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.1 GO:0015862 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.0 0.1 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.3 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.2 GO:0051414 response to cortisol(GO:0051414)
0.0 0.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.1 GO:0050902 leukocyte adhesive activation(GO:0050902)
0.0 0.0 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.6 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.2 GO:0043129 surfactant homeostasis(GO:0043129)
0.0 0.4 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.0 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.0 0.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.2 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.3 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.2 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.1 GO:0001812 regulation of type I hypersensitivity(GO:0001810) positive regulation of type I hypersensitivity(GO:0001812) type I hypersensitivity(GO:0016068)
0.0 0.3 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.1 GO:1904106 protein localization to microvillus(GO:1904106)
0.0 0.2 GO:0035608 protein deglutamylation(GO:0035608)
0.0 0.1 GO:0010989 negative regulation of lipoprotein particle clearance(GO:0010985) negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.0 GO:0002763 positive regulation of myeloid leukocyte differentiation(GO:0002763)
0.0 0.2 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.1 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.1 GO:0044146 negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.0 0.1 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.1 GO:2001176 mediator complex assembly(GO:0036034) regulation of mediator complex assembly(GO:2001176) positive regulation of mediator complex assembly(GO:2001178)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.1 GO:1990697 protein depalmitoleylation(GO:1990697)
0.0 0.1 GO:0036509 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 0.1 GO:0097473 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.1 GO:0009213 pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213)
0.0 0.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:0048484 enteric nervous system development(GO:0048484)
0.0 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.2 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.0 0.1 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.2 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.2 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.0 0.1 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.0 0.1 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.1 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.0 0.1 GO:0008218 bioluminescence(GO:0008218)
0.0 0.2 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.0 0.1 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:0036309 protein localization to M-band(GO:0036309)
0.0 0.4 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
0.0 0.1 GO:0002634 regulation of germinal center formation(GO:0002634)
0.0 0.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.4 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.0 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.3 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0070845 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.0 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.1 GO:1902966 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.0 0.0 GO:0043105 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.0 0.0 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.1 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.0 GO:0031133 regulation of axon diameter(GO:0031133)
0.0 0.1 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.5 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.0 0.3 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.0 GO:0001878 response to yeast(GO:0001878)
0.0 0.2 GO:0046185 aldehyde catabolic process(GO:0046185)
0.0 0.1 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.1 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0 0.2 GO:0015866 ADP transport(GO:0015866)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.3 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.3 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.0 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232)
0.0 0.3 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0048858 cell projection morphogenesis(GO:0048858)
0.0 0.0 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.0 0.0 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.1 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.2 GO:0044857 plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857)
0.0 0.4 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.0 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.1 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.0 0.0 GO:0050757 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 0.0 GO:0007341 penetration of zona pellucida(GO:0007341)
0.0 0.0 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.0 0.1 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.2 GO:0072643 interferon-gamma secretion(GO:0072643)
0.0 0.2 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.1 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.3 GO:0051775 response to redox state(GO:0051775)
0.0 0.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.5 GO:0032878 regulation of establishment or maintenance of cell polarity(GO:0032878)
0.0 0.1 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.0 0.7 GO:0006968 cellular defense response(GO:0006968)
0.0 0.2 GO:0051014 actin filament severing(GO:0051014)
0.0 0.0 GO:1904528 positive regulation of microtubule binding(GO:1904528)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.2 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.2 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.2 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.3 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)
0.0 0.0 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.0 0.0 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
0.0 0.1 GO:0070560 protein secretion by platelet(GO:0070560)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.1 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 0.1 GO:0030035 microspike assembly(GO:0030035)
0.0 0.0 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.2 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.5 GO:0035902 response to immobilization stress(GO:0035902)
0.0 0.2 GO:0007172 signal complex assembly(GO:0007172)
0.0 0.1 GO:0003149 membranous septum morphogenesis(GO:0003149) muscular septum morphogenesis(GO:0003150)
0.0 0.1 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.2 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.0 GO:0048210 Golgi vesicle fusion to target membrane(GO:0048210)
0.0 0.1 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.1 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.0 0.0 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.0 0.0 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.1 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.0 0.1 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.2 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.0 GO:0060374 mast cell differentiation(GO:0060374)
0.0 0.2 GO:0002097 tRNA wobble base modification(GO:0002097)
0.0 0.3 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.2 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.0 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.2 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.5 GO:0019228 neuronal action potential(GO:0019228)
0.0 0.1 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.3 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.0 0.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.0 0.1 GO:0002278 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil activation(GO:0043307) eosinophil degranulation(GO:0043308)
0.0 0.0 GO:1905045 Schwann cell proliferation involved in axon regeneration(GO:0014011) negative regulation of Schwann cell migration(GO:1900148) regulation of Schwann cell proliferation involved in axon regeneration(GO:1905044) negative regulation of Schwann cell proliferation involved in axon regeneration(GO:1905045)
0.0 0.2 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.1 GO:0016071 mRNA metabolic process(GO:0016071)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.3 GO:0002081 outer acrosomal membrane(GO:0002081)
0.1 0.3 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 0.3 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.1 0.8 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.3 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.3 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 0.2 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 0.4 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.2 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.1 0.5 GO:0061574 ASAP complex(GO:0061574)
0.1 1.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.7 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.4 GO:0036128 CatSper complex(GO:0036128)
0.0 0.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.2 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.1 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.3 GO:0045177 apical part of cell(GO:0045177)
0.0 0.1 GO:0031085 BLOC-3 complex(GO:0031085)
0.0 0.2 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.2 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.8 GO:0042599 lamellar body(GO:0042599)
0.0 0.4 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.1 GO:1902912 pyruvate kinase complex(GO:1902912)
0.0 0.1 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.0 0.1 GO:0005608 laminin-3 complex(GO:0005608)
0.0 0.7 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.6 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 1.0 GO:0031105 septin complex(GO:0031105)
0.0 0.2 GO:0042627 chylomicron(GO:0042627)
0.0 0.3 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.1 GO:0044393 microspike(GO:0044393)
0.0 0.1 GO:0042827 platelet dense granule membrane(GO:0031088) platelet dense granule(GO:0042827)
0.0 0.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.3 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.4 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.2 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0002133 polycystin complex(GO:0002133)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0097361 CIA complex(GO:0097361)
0.0 0.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.3 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.1 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.6 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.0 1.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.0 GO:1903095 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.0 0.1 GO:0071020 post-spliceosomal complex(GO:0071020)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.0 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.6 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.1 GO:0070701 mucus layer(GO:0070701)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.3 GO:0038201 TORC2 complex(GO:0031932) TOR complex(GO:0038201)
0.0 0.3 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:0000243 commitment complex(GO:0000243)
0.0 0.1 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.3 GO:0000812 Swr1 complex(GO:0000812)
0.0 1.4 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.0 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.1 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.3 GO:0071565 nBAF complex(GO:0071565)
0.0 1.0 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.1 GO:0097225 sperm midpiece(GO:0097225)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0030492 hemoglobin binding(GO:0030492)
0.1 0.4 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.4 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.6 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
0.1 0.4 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.1 0.7 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.1 0.8 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 0.4 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.1 0.3 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
0.1 0.3 GO:0042007 interleukin-18 binding(GO:0042007)
0.1 0.3 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 0.4 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.1 0.9 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.8 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.1 0.5 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 0.4 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.4 GO:0005124 scavenger receptor binding(GO:0005124)
0.1 0.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.3 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.5 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.1 0.2 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.1 0.2 GO:0048030 disaccharide binding(GO:0048030)
0.1 0.2 GO:0002113 interleukin-33 binding(GO:0002113)
0.1 0.5 GO:0052796 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 0.3 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.1 0.2 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.2 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 0.4 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.1 1.0 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.1 0.3 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 0.2 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.4 GO:0016936 galactoside binding(GO:0016936)
0.1 0.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.4 GO:0043426 MRF binding(GO:0043426)
0.0 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0 0.4 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.2 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 0.2 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.2 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0 0.7 GO:0043995 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.2 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.0 0.1 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677)
0.0 0.4 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.3 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.2 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.0 0.2 GO:0045569 TRAIL binding(GO:0045569)
0.0 0.1 GO:0047726 iron-cytochrome-c reductase activity(GO:0047726)
0.0 0.2 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 0.8 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.0 0.3 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0 0.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.2 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.4 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.2 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.7 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.2 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.0 0.1 GO:0097689 iron channel activity(GO:0097689)
0.0 0.3 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 1.8 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0086040 sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086040)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.3 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.2 GO:0102008 cytosolic dipeptidase activity(GO:0102008)
0.0 0.2 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.1 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.0 0.2 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.2 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.1 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.7 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0032190 acrosin binding(GO:0032190)
0.0 0.2 GO:1901611 phosphatidylglycerol binding(GO:1901611)
0.0 1.1 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 0.1 GO:0070984 SET domain binding(GO:0070984)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.2 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.1 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.2 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0034039 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity(GO:0034039)
0.0 0.1 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.1 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.0 0.9 GO:0005521 lamin binding(GO:0005521)
0.0 0.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0019864 IgG binding(GO:0019864)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.1 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.3 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0005497 androgen binding(GO:0005497)
0.0 0.1 GO:0004348 glucosylceramidase activity(GO:0004348)
0.0 0.4 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.1 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.3 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.1 GO:0047820 D-glutamate cyclase activity(GO:0047820)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.2 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.2 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.1 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.0 0.1 GO:1990699 palmitoleyl hydrolase activity(GO:1990699)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.1 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.0 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.0 0.1 GO:0004743 pyruvate kinase activity(GO:0004743)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.0 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.0 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.2 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.1 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.0 0.1 GO:0008035 high-density lipoprotein particle binding(GO:0008035)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.0 0.1 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.3 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.0 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.0 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.4 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.4 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.0 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.2 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.0 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.1 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.0 0.3 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.0 GO:0031896 alpha-1A adrenergic receptor binding(GO:0031691) follicle-stimulating hormone receptor binding(GO:0031762) V2 vasopressin receptor binding(GO:0031896)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.2 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.3 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0045499 chemorepellent activity(GO:0045499)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.1 ST ADRENERGIC Adrenergic Pathway
0.0 0.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 3.5 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.1 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.9 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.2 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 1.3 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.4 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.2 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.7 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.3 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 1.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.6 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.5 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.9 PID FGF PATHWAY FGF signaling pathway
0.0 1.3 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.7 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.9 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.7 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.7 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 1.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.7 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 1.1 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.4 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 1.6 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.7 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.1 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA