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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for RELB

Z-value: 0.68

Motif logo

Transcription factors associated with RELB

Gene Symbol Gene ID Gene Info
ENSG00000104856.9 RELB proto-oncogene, NF-kB subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RELBhg19_v2_chr19_+_45504688_455047820.079.0e-01Click!

Activity profile of RELB motif

Sorted Z-values of RELB motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_6845578 0.53 ENST00000467404.2
ENST00000439411.2
calmodulin binding transcription activator 1
chr12_-_86230315 0.51 ENST00000361228.3
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr6_-_30080863 0.49 ENST00000540829.1
tripartite motif containing 31
chr2_-_191885686 0.46 ENST00000432058.1
signal transducer and activator of transcription 1, 91kDa
chr22_-_28490123 0.45 ENST00000442232.1
tetratricopeptide repeat domain 28
chr9_-_32526299 0.42 ENST00000379882.1
ENST00000379883.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr9_-_32526184 0.42 ENST00000545044.1
ENST00000379868.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr2_-_163175133 0.39 ENST00000421365.2
ENST00000263642.2
interferon induced with helicase C domain 1
chr6_-_30080876 0.39 ENST00000376734.3
tripartite motif containing 31
chr9_-_140335789 0.34 ENST00000344119.2
ENST00000371506.2
ectonucleoside triphosphate diphosphohydrolase 8
chr14_+_38065052 0.34 ENST00000556845.1
tetratricopeptide repeat domain 6
chr18_+_44526786 0.33 ENST00000245121.5
ENST00000356157.7
katanin p60 subunit A-like 2
chr4_-_74864386 0.32 ENST00000296027.4
chemokine (C-X-C motif) ligand 5
chr1_+_95975672 0.31 ENST00000440116.2
ENST00000456933.1
RP11-286B14.1
chr1_+_56880606 0.31 ENST00000451914.1
RP4-710M16.2
chr1_+_186649754 0.31 ENST00000608917.1
RP5-973M2.2
chr4_-_185395191 0.28 ENST00000510814.1
ENST00000507523.1
ENST00000506230.1
interferon regulatory factor 2
chr1_-_186649543 0.28 ENST00000367468.5
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr4_-_74904398 0.27 ENST00000296026.4
chemokine (C-X-C motif) ligand 3
chr11_+_18287801 0.27 ENST00000532858.1
ENST00000405158.2
serum amyloid A1
chr17_+_48351785 0.26 ENST00000507382.1
transmembrane protein 92
chr15_+_57891609 0.26 ENST00000569089.1
myocardial zonula adherens protein
chrX_-_20284733 0.26 ENST00000438357.1
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr4_+_74702214 0.26 ENST00000226317.5
ENST00000515050.1
chemokine (C-X-C motif) ligand 6
chr15_+_45544426 0.25 ENST00000347644.3
ENST00000560438.1
solute carrier family 28 (concentrative nucleoside transporter), member 2
chr1_+_6845497 0.25 ENST00000473578.1
ENST00000557126.1
calmodulin binding transcription activator 1
chr11_+_34642656 0.22 ENST00000257831.3
ENST00000450654.2
ets homologous factor
chr16_+_2059872 0.22 ENST00000567649.1
neuropeptide W
chr8_-_33330595 0.22 ENST00000524021.1
ENST00000335589.3
fucosyltransferase 10 (alpha (1,3) fucosyltransferase)
chr4_-_79860506 0.22 ENST00000295462.3
ENST00000380645.4
ENST00000512733.1
progestin and adipoQ receptor family member III
chr1_-_101491319 0.21 ENST00000342173.7
ENST00000488176.1
ENST00000370109.3
diphthamide biosynthesis 5
chr19_+_4769117 0.21 ENST00000540211.1
ENST00000317292.3
ENST00000586721.1
ENST00000592709.1
ENST00000588711.1
ENST00000589639.1
ENST00000591008.1
ENST00000592663.1
ENST00000588758.1
MIR7-3 host gene (non-protein coding)
chr4_+_74735102 0.21 ENST00000395761.3
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr14_-_35873856 0.20 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr5_-_127418573 0.20 ENST00000508353.1
ENST00000508878.1
ENST00000501652.1
ENST00000514409.1
CTC-228N24.3
chr6_+_138188351 0.20 ENST00000421450.1
tumor necrosis factor, alpha-induced protein 3
chr13_-_107214291 0.19 ENST00000375926.1
arginine and glutamate rich 1
chr4_-_74964904 0.19 ENST00000508487.2
chemokine (C-X-C motif) ligand 2
chr15_+_34394257 0.19 ENST00000397766.2
piggyBac transposable element derived 4
chr2_+_211421262 0.19 ENST00000233072.5
carbamoyl-phosphate synthase 1, mitochondrial
chr6_+_126221034 0.18 ENST00000433571.1
nuclear receptor coactivator 7
chr20_-_36156264 0.18 ENST00000445723.1
ENST00000414080.1
bladder cancer associated protein
chr7_+_22766766 0.17 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
interleukin 6 (interferon, beta 2)
chr10_+_70661014 0.17 ENST00000373585.3
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
chr9_-_130693048 0.17 ENST00000388747.4
phosphatidylinositol-4-phosphate 5-kinase-like 1
chr12_-_31945172 0.17 ENST00000340398.3
H3 histone, family 3C
chr20_+_44035200 0.17 ENST00000372717.1
ENST00000360981.4
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr10_+_30722866 0.17 ENST00000263056.1
mitogen-activated protein kinase kinase kinase 8
chrX_-_21776281 0.17 ENST00000379494.3
small muscle protein, X-linked
chr14_+_96858433 0.16 ENST00000267584.4
adenylate kinase 7
chr3_+_53195517 0.16 ENST00000487897.1
protein kinase C, delta
chr15_+_33010175 0.16 ENST00000300177.4
ENST00000560677.1
ENST00000560830.1
gremlin 1, DAN family BMP antagonist
chr7_+_89783689 0.16 ENST00000297205.2
six transmembrane epithelial antigen of the prostate 1
chr12_+_100867486 0.16 ENST00000548884.1
nuclear receptor subfamily 1, group H, member 4
chr6_-_24358264 0.16 ENST00000378454.3
doublecortin domain containing 2
chr1_-_146644036 0.16 ENST00000425272.2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr12_+_100867694 0.15 ENST00000392986.3
ENST00000549996.1
nuclear receptor subfamily 1, group H, member 4
chr16_+_85932760 0.15 ENST00000565552.1
interferon regulatory factor 8
chr14_+_96858454 0.15 ENST00000555570.1
adenylate kinase 7
chr12_+_104324112 0.15 ENST00000299767.5
heat shock protein 90kDa beta (Grp94), member 1
chr10_-_73975657 0.15 ENST00000394919.1
ENST00000526751.1
activating signal cointegrator 1 complex subunit 1
chr11_+_102188272 0.15 ENST00000532808.1
baculoviral IAP repeat containing 3
chr1_-_1356719 0.15 ENST00000520296.1
ankyrin repeat domain 65
chr1_+_178694362 0.15 ENST00000367634.2
Ral GEF with PH domain and SH3 binding motif 2
chr11_+_102188224 0.15 ENST00000263464.3
baculoviral IAP repeat containing 3
chr4_+_185395947 0.14 ENST00000605834.1
RP11-326I11.3
chrX_-_131352152 0.14 ENST00000342983.2
RAP2C, member of RAS oncogene family
chr12_+_94551874 0.14 ENST00000551850.1
plexin C1
chr2_+_113735575 0.14 ENST00000376489.2
ENST00000259205.4
interleukin 36, gamma
chr3_+_197518100 0.14 ENST00000438796.2
ENST00000414675.2
ENST00000441090.2
ENST00000334859.4
ENST00000425562.2
leucine-rich repeats and calponin homology (CH) domain containing 3
chr12_-_95942563 0.14 ENST00000549639.1
ENST00000551837.1
ubiquitin specific peptidase 44
chr3_+_63805017 0.13 ENST00000295896.8
chromosome 3 open reading frame 49
chr12_-_105630016 0.13 ENST00000258530.3
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr22_-_41215291 0.13 ENST00000542412.1
ENST00000544408.1
solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
chr1_+_94883931 0.13 ENST00000394233.2
ENST00000454898.2
ENST00000536817.1
ATP-binding cassette, sub-family D (ALD), member 3
chr3_+_107364769 0.13 ENST00000449271.1
ENST00000425868.1
ENST00000449213.1
bobby sox homolog (Drosophila)
chr7_-_69062391 0.13 ENST00000436600.2
RP5-942I16.1
chrX_-_72347916 0.13 ENST00000373518.1
nucleosome assembly protein 1-like 6
chrX_+_108780347 0.13 ENST00000372103.1
nuclear transport factor 2-like export factor 2
chr1_+_94884023 0.13 ENST00000315713.5
ATP-binding cassette, sub-family D (ALD), member 3
chr4_+_113152978 0.13 ENST00000309703.6
adaptor-related protein complex 1 associated regulatory protein
chr17_+_38024417 0.13 ENST00000348931.4
ENST00000583811.1
ENST00000584588.1
ENST00000377940.3
zona pellucida binding protein 2
chr3_-_138048682 0.13 ENST00000383180.2
NME/NM23 family member 9
chr12_+_96588368 0.13 ENST00000547860.1
ELK3, ETS-domain protein (SRF accessory protein 2)
chr12_-_14721283 0.13 ENST00000240617.5
phospholipase B domain containing 1
chr10_-_73976025 0.13 ENST00000342444.4
ENST00000533958.1
ENST00000527593.1
ENST00000394915.3
ENST00000530461.1
ENST00000317168.6
ENST00000524829.1
activating signal cointegrator 1 complex subunit 1
chr2_+_232646379 0.12 ENST00000410024.1
ENST00000409295.1
ENST00000409091.1
COP9 signalosome subunit 7B
chr14_+_71788096 0.12 ENST00000557151.1
signal-induced proliferation-associated 1 like 1
chr3_+_133524459 0.12 ENST00000484684.1
signal recognition particle receptor, B subunit
chr5_+_122847908 0.12 ENST00000511130.2
ENST00000512718.3
casein kinase 1, gamma 3
chr8_-_128231299 0.12 ENST00000500112.1
colon cancer associated transcript 1 (non-protein coding)
chr12_-_56221330 0.12 ENST00000546837.1
Uncharacterized protein
chr8_-_90769939 0.12 ENST00000504145.1
ENST00000519655.2
RP11-37B2.1
chr1_-_8000872 0.12 ENST00000377507.3
tumor necrosis factor receptor superfamily, member 9
chr5_+_134181625 0.11 ENST00000394976.3
chromosome 5 open reading frame 24
chr12_-_117537240 0.11 ENST00000392545.4
ENST00000541210.1
ENST00000335209.7
tescalcin
chr15_-_66084621 0.11 ENST00000564674.1
DENN/MADD domain containing 4A
chr6_+_138188378 0.11 ENST00000420009.1
tumor necrosis factor, alpha-induced protein 3
chr18_+_20513782 0.11 ENST00000399722.2
ENST00000399725.2
ENST00000399721.2
ENST00000583594.1
retinoblastoma binding protein 8
chr1_+_75594119 0.11 ENST00000294638.5
LIM homeobox 8
chr20_+_34680595 0.11 ENST00000406771.2
erythrocyte membrane protein band 4.1-like 1
chr11_+_126262027 0.11 ENST00000526311.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chrX_+_108779870 0.10 ENST00000372107.1
nuclear transport factor 2-like export factor 2
chr12_-_108991778 0.10 ENST00000549447.1
transmembrane protein 119
chr8_-_16859690 0.10 ENST00000180166.5
fibroblast growth factor 20
chr21_-_16437126 0.10 ENST00000318948.4
nuclear receptor interacting protein 1
chr12_+_56473628 0.10 ENST00000549282.1
ENST00000549061.1
ENST00000267101.3
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
chr2_+_208394455 0.10 ENST00000430624.1
cAMP responsive element binding protein 1
chr7_-_22539771 0.10 ENST00000406890.2
ENST00000424363.1
STEAP family member 1B
chr8_+_75262612 0.10 ENST00000220822.7
ganglioside induced differentiation associated protein 1
chr8_-_81083341 0.10 ENST00000519303.2
tumor protein D52
chr17_-_19880992 0.10 ENST00000395536.3
ENST00000576896.1
ENST00000225737.6
A kinase (PRKA) anchor protein 10
chr11_-_64570706 0.10 ENST00000294066.2
ENST00000377350.3
mitogen-activated protein kinase kinase kinase kinase 2
chr5_-_132073111 0.10 ENST00000403231.1
kinesin family member 3A
chr1_+_94883991 0.10 ENST00000370214.4
ATP-binding cassette, sub-family D (ALD), member 3
chr3_+_113775576 0.10 ENST00000485050.1
ENST00000281273.4
queuine tRNA-ribosyltransferase domain containing 1
chr14_+_65878565 0.10 ENST00000556518.1
ENST00000557164.1
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr18_-_71959159 0.10 ENST00000494131.2
ENST00000397914.4
ENST00000340533.4
cytochrome b5 type A (microsomal)
chr1_+_24118452 0.10 ENST00000421070.1
lysophospholipase II
chr2_+_201987200 0.10 ENST00000425030.1
CASP8 and FADD-like apoptosis regulator
chr17_+_45908974 0.09 ENST00000269025.4
leucine rich repeat containing 46
chr21_-_16437255 0.09 ENST00000400199.1
ENST00000400202.1
nuclear receptor interacting protein 1
chr9_+_101705893 0.09 ENST00000375001.3
collagen, type XV, alpha 1
chr21_-_44898015 0.09 ENST00000332440.3
long intergenic non-protein coding RNA 313
chr14_+_88852059 0.09 ENST00000045347.7
spermatogenesis associated 7
chr1_-_205904950 0.09 ENST00000340781.4
solute carrier family 26 (anion exchanger), member 9
chr10_+_95848824 0.09 ENST00000371385.3
ENST00000371375.1
phospholipase C, epsilon 1
chr15_+_83209620 0.09 ENST00000568285.1
Uncharacterized protein
chr3_+_160822462 0.09 ENST00000468606.1
ENST00000460503.1
NMD3 ribosome export adaptor
chr16_-_15188106 0.09 ENST00000429751.2
ENST00000564131.1
ENST00000563559.1
ENST00000198767.6
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chr1_+_6845384 0.09 ENST00000303635.7
calmodulin binding transcription activator 1
chr4_-_52904425 0.09 ENST00000535450.1
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
chr4_-_185275104 0.09 ENST00000317596.3
RP11-290F5.2
chr10_+_86088381 0.09 ENST00000224756.8
ENST00000372088.2
coiled-coil serine-rich protein 2
chr2_-_56150184 0.09 ENST00000394554.1
EGF containing fibulin-like extracellular matrix protein 1
chrX_+_18443703 0.09 ENST00000379996.3
cyclin-dependent kinase-like 5
chr8_+_90770008 0.08 ENST00000540020.1
receptor-interacting serine-threonine kinase 2
chr5_-_16509101 0.08 ENST00000399793.2
family with sequence similarity 134, member B
chr4_-_170897045 0.08 ENST00000508313.1
RP11-205M3.3
chr2_+_68694678 0.08 ENST00000303795.4
aprataxin and PNKP like factor
chr16_+_50730910 0.08 ENST00000300589.2
nucleotide-binding oligomerization domain containing 2
chr12_-_54982420 0.08 ENST00000257905.8
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr10_-_75173785 0.08 ENST00000535178.1
ENST00000372921.5
ENST00000372919.4
annexin A7
chr1_-_247242048 0.08 ENST00000366503.2
zinc finger protein 670
chr8_+_22446763 0.08 ENST00000450780.2
ENST00000430850.2
ENST00000447849.1
Uncharacterized protein
chr2_+_202316392 0.08 ENST00000194530.3
ENST00000392249.2
STE20-related kinase adaptor beta
chr5_+_122847781 0.08 ENST00000395412.1
ENST00000395411.1
ENST00000345990.4
casein kinase 1, gamma 3
chr8_+_72755796 0.08 ENST00000524152.1
Protein LOC100132891; cDNA FLJ53548
chr12_-_120966943 0.08 ENST00000552443.1
ENST00000547736.1
ENST00000445328.2
ENST00000547943.1
ENST00000288532.6
coenzyme Q5 homolog, methyltransferase (S. cerevisiae)
chr6_+_138188551 0.08 ENST00000237289.4
ENST00000433680.1
tumor necrosis factor, alpha-induced protein 3
chr16_+_89686991 0.08 ENST00000393092.3
dipeptidase 1 (renal)
chr17_+_40985407 0.08 ENST00000586114.1
ENST00000590720.1
ENST00000585805.1
ENST00000541124.1
ENST00000441946.2
ENST00000591152.1
ENST00000589469.1
ENST00000293362.3
ENST00000592169.1
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr3_-_107941230 0.08 ENST00000264538.3
intraflagellar transport 57 homolog (Chlamydomonas)
chr21_+_34775772 0.08 ENST00000405436.1
interferon gamma receptor 2 (interferon gamma transducer 1)
chr19_+_10527449 0.08 ENST00000592685.1
ENST00000380702.2
phosphodiesterase 4A, cAMP-specific
chrX_-_102510045 0.08 ENST00000360000.4
transcription elongation factor A (SII)-like 8
chr10_+_71078595 0.08 ENST00000359426.6
hexokinase 1
chr8_+_90769967 0.08 ENST00000220751.4
receptor-interacting serine-threonine kinase 2
chr14_+_24701628 0.08 ENST00000355299.4
ENST00000559836.1
guanosine monophosphate reductase 2
chr17_-_75878647 0.08 ENST00000374983.2
FLJ45079
chr1_-_95392635 0.08 ENST00000538964.1
ENST00000394202.4
ENST00000370206.4
calponin 3, acidic
chr19_-_17958771 0.08 ENST00000534444.1
Janus kinase 3
chr10_+_77056181 0.08 ENST00000526759.1
ENST00000533822.1
ZNF503 antisense RNA 1
chr8_-_101962777 0.08 ENST00000395951.3
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
chr5_+_139781393 0.07 ENST00000360839.2
ENST00000297183.6
ENST00000421134.1
ENST00000394723.3
ENST00000511151.1
ankyrin repeat and KH domain containing 1
chr3_-_119379719 0.07 ENST00000493094.1
popeye domain containing 2
chr12_+_78224667 0.07 ENST00000549464.1
neuron navigator 3
chr5_-_132073210 0.07 ENST00000378735.1
ENST00000378746.4
kinesin family member 3A
chr12_-_57023995 0.07 ENST00000549884.1
ENST00000546695.1
bromodomain adjacent to zinc finger domain, 2A
chr4_-_85887503 0.07 ENST00000509172.1
ENST00000322366.6
ENST00000295888.4
ENST00000502713.1
WD repeat and FYVE domain containing 3
chr14_+_65878650 0.07 ENST00000555559.1
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr6_-_32821599 0.07 ENST00000354258.4
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr9_+_4490394 0.07 ENST00000262352.3
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr1_-_209979375 0.07 ENST00000367021.3
interferon regulatory factor 6
chr5_+_82767284 0.07 ENST00000265077.3
versican
chr2_-_204400113 0.07 ENST00000319170.5
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr17_+_34900737 0.07 ENST00000304718.4
ENST00000485685.2
gametogenetin binding protein 2
chr2_-_36779411 0.07 ENST00000406220.1
Uncharacterized protein
chr10_+_89124746 0.07 ENST00000465545.1
NUT family member 2D
chr5_+_139781445 0.07 ENST00000532219.1
ENST00000394722.3
ANKHD1-EIF4EBP3 readthrough
ankyrin repeat and KH domain containing 1
chr3_-_113775328 0.07 ENST00000483766.1
ENST00000545063.1
ENST00000491000.1
ENST00000295878.3
KIAA1407
chr3_-_69402828 0.07 ENST00000460709.1
FERM domain containing 4B
chr11_+_10772847 0.07 ENST00000524523.1
CTR9, Paf1/RNA polymerase II complex component
chr1_+_112939121 0.07 ENST00000441739.1
CTTNBP2 N-terminal like
chr5_-_94890648 0.07 ENST00000513823.1
ENST00000514952.1
ENST00000358746.2
tetratricopeptide repeat domain 37
chr9_+_35792151 0.07 ENST00000342694.2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr8_+_75262629 0.07 ENST00000434412.2
ganglioside induced differentiation associated protein 1
chr11_-_75062829 0.07 ENST00000393505.4
arrestin, beta 1
chr8_-_95229531 0.07 ENST00000450165.2
cadherin 17, LI cadherin (liver-intestine)
chr10_+_49514698 0.06 ENST00000432379.1
ENST00000429041.1
ENST00000374189.1
mitogen-activated protein kinase 8
chr2_+_114163945 0.06 ENST00000453673.3
immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr19_-_6591113 0.06 ENST00000423145.3
ENST00000245903.3
CD70 molecule
chr4_-_114900126 0.06 ENST00000541197.1
arylsulfatase family, member J
chr21_+_34775698 0.06 ENST00000381995.1
interferon gamma receptor 2 (interferon gamma transducer 1)
chr10_+_88428206 0.06 ENST00000429277.2
ENST00000458213.2
ENST00000352360.5
LIM domain binding 3
chr6_-_11779840 0.06 ENST00000506810.1
androgen-dependent TFPI-regulating protein
chr3_+_107364683 0.06 ENST00000413213.1
bobby sox homolog (Drosophila)
chr5_-_43313269 0.06 ENST00000511774.1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr7_+_134212312 0.06 ENST00000359579.4
aldo-keto reductase family 1, member B10 (aldose reductase)
chr2_+_32853093 0.06 ENST00000448773.1
ENST00000317907.4
tetratricopeptide repeat domain 27

Network of associatons between targets according to the STRING database.

First level regulatory network of RELB

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.4 GO:0072573 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
0.1 0.5 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.1 0.3 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.4 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.2 GO:0090291 negative regulation of osteoclast proliferation(GO:0090291)
0.1 0.3 GO:0072615 nitrogen catabolite regulation of transcription from RNA polymerase II promoter(GO:0001079) nitrogen catabolite activation of transcription from RNA polymerase II promoter(GO:0001080) regulation of urea metabolic process(GO:0034255) intracellular bile acid receptor signaling pathway(GO:0038185) interleukin-17 secretion(GO:0072615) nitrogen catabolite regulation of transcription(GO:0090293) nitrogen catabolite activation of transcription(GO:0090294) regulation of nitrogen cycle metabolic process(GO:1903314) positive regulation of glutamate metabolic process(GO:2000213) regulation of ammonia assimilation cycle(GO:2001248) positive regulation of ammonia assimilation cycle(GO:2001250)
0.1 0.4 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 0.2 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 0.2 GO:1903718 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.1 0.2 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.1 GO:0043132 coenzyme A transport(GO:0015880) coenzyme A transmembrane transport(GO:0035349) NAD transport(GO:0043132) adenosine 3',5'-bisphosphate transmembrane transport(GO:0071106) AMP transport(GO:0080121)
0.0 0.2 GO:0002384 hepatic immune response(GO:0002384) response to prolactin(GO:1990637)
0.0 0.2 GO:0036071 N-glycan fucosylation(GO:0036071)
0.0 0.3 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.0 0.2 GO:0071684 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.2 GO:0002730 regulation of dendritic cell cytokine production(GO:0002730)
0.0 0.3 GO:0009133 nucleoside diphosphate biosynthetic process(GO:0009133)
0.0 0.3 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.3 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.0 0.9 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.2 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.1 GO:0016999 antibiotic metabolic process(GO:0016999)
0.0 0.1 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.2 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.1 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
0.0 0.1 GO:2000657 regulation of apolipoprotein binding(GO:2000656) negative regulation of apolipoprotein binding(GO:2000657)
0.0 0.1 GO:0016107 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488)
0.0 0.2 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0046832 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.0 0.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.1 GO:0046967 cytosol to ER transport(GO:0046967)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:2001162 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.0 0.1 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.1 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.1 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 1.2 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 0.1 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0 0.0 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.0 0.2 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.1 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.2 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.0 GO:0007506 gonadal mesoderm development(GO:0007506)
0.0 0.0 GO:1901228 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.0 0.1 GO:0051106 positive regulation of DNA ligation(GO:0051106)
0.0 0.1 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.0 0.0 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.2 GO:0033690 positive regulation of osteoblast proliferation(GO:0033690)
0.0 0.0 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.1 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.1 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.9 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.1 GO:0061317 canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.2 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.5 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.1 GO:0097635 extrinsic component of autophagosome membrane(GO:0097635)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.4 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.2 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.1 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.0 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.0 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.0 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.1 GO:1902560 GMP reductase complex(GO:1902560)
0.0 0.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.0 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.0 0.1 GO:0042824 MHC class I peptide loading complex(GO:0042824) TAP complex(GO:0042825)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.3 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.1 0.3 GO:1902122 chenodeoxycholic acid binding(GO:1902122)
0.1 0.3 GO:0050473 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.1 0.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.2 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.2 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.0 0.1 GO:0071077 coenzyme A transmembrane transporter activity(GO:0015228) adenosine 3',5'-bisphosphate transmembrane transporter activity(GO:0071077) AMP transmembrane transporter activity(GO:0080122)
0.0 0.3 GO:0004127 cytidylate kinase activity(GO:0004127)
0.0 0.2 GO:0046921 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.0 0.1 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.0 0.3 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.4 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.2 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.1 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0045550 geranylgeranyl reductase activity(GO:0045550)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.2 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0 0.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.2 GO:0016015 morphogen activity(GO:0016015)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.0 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.0 0.1 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0046979 TAP2 binding(GO:0046979)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.3 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.8 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.7 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.2 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.3 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.0 0.9 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR