Project

A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

Navigation
Downloads

Results for RELA

Z-value: 1.73

Motif logo

logo of

Transcription factors associated with RELA

Gene Symbol Gene ID Gene Info
RELA
ENSG00000173039.14 RELA proto-oncogene, NF-kB subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RELAhg19_v2_chr11_-_65430554_65430579-0.592.1e-01Click!

Activity profile of RELA motif

Sorted Z-values of RELA motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_74964904 2.44 ENST00000508487.2
CXCL2
chemokine (C-X-C motif) ligand 2
chr11_+_34642656 2.39 ENST00000257831.3
ENST00000450654.2
EHF
ets homologous factor
chr2_-_163175133 2.39 ENST00000421365.2
ENST00000263642.2
IFIH1
interferon induced with helicase C domain 1
chr4_-_74904398 2.31 ENST00000296026.4
CXCL3
chemokine (C-X-C motif) ligand 3
chr14_-_35873856 2.25 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr6_+_138188351 2.12 ENST00000421450.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr2_+_228678550 1.96 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr2_-_191885686 1.94 ENST00000432058.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr20_-_62203808 1.89 ENST00000467148.1
HELZ2
helicase with zinc finger 2, transcriptional coactivator
chr4_-_74864386 1.83 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr4_+_74735102 1.66 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr10_+_30722866 1.62 ENST00000263056.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr10_+_30723105 1.61 ENST00000375322.2
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr6_+_138188551 1.45 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr4_-_76944621 1.42 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr19_+_496454 1.41 ENST00000346144.4
ENST00000215637.3
ENST00000382683.4
MADCAM1
mucosal vascular addressin cell adhesion molecule 1
chr10_+_30723045 1.35 ENST00000542547.1
ENST00000415139.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr1_+_6845384 1.34 ENST00000303635.7
CAMTA1
calmodulin binding transcription activator 1
chr9_-_32526184 1.32 ENST00000545044.1
ENST00000379868.1
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr6_+_138188378 1.32 ENST00000420009.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr9_-_32526299 1.29 ENST00000379882.1
ENST00000379883.2
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr11_+_102188272 1.16 ENST00000532808.1
BIRC3
baculoviral IAP repeat containing 3
chr4_-_164253738 1.14 ENST00000509586.1
ENST00000504391.1
ENST00000512819.1
NPY1R
neuropeptide Y receptor Y1
chr1_-_186649543 1.14 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr15_+_44719996 1.11 ENST00000559793.1
ENST00000558968.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr4_+_74702214 1.08 ENST00000226317.5
ENST00000515050.1
CXCL6
chemokine (C-X-C motif) ligand 6
chr7_+_22766766 1.06 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr11_+_102188224 1.03 ENST00000263464.3
BIRC3
baculoviral IAP repeat containing 3
chr11_+_18287721 1.00 ENST00000356524.4
SAA1
serum amyloid A1
chr5_+_159895275 0.92 ENST00000517927.1
MIR146A
microRNA 146a
chr5_-_55290773 0.92 ENST00000502326.3
ENST00000381298.2
IL6ST
interleukin 6 signal transducer (gp130, oncostatin M receptor)
chr2_+_161993412 0.89 ENST00000259075.2
ENST00000432002.1
TANK
TRAF family member-associated NFKB activator
chr1_+_56880606 0.89 ENST00000451914.1
RP4-710M16.2
RP4-710M16.2
chr17_-_34207295 0.88 ENST00000463941.1
ENST00000293272.3
CCL5
chemokine (C-C motif) ligand 5
chr11_+_18287801 0.87 ENST00000532858.1
ENST00000405158.2
SAA1
serum amyloid A1
chr1_+_6845497 0.87 ENST00000473578.1
ENST00000557126.1
CAMTA1
calmodulin binding transcription activator 1
chr11_-_46141338 0.85 ENST00000529782.1
ENST00000532010.1
ENST00000525438.1
ENST00000533757.1
ENST00000527782.1
PHF21A
PHD finger protein 21A
chr19_+_4229495 0.85 ENST00000221847.5
EBI3
Epstein-Barr virus induced 3
chr12_+_49761147 0.83 ENST00000549298.1
SPATS2
spermatogenesis associated, serine-rich 2
chr6_+_29691198 0.83 ENST00000440587.2
ENST00000434407.2
HLA-F
major histocompatibility complex, class I, F
chr13_-_52027134 0.82 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr15_+_44719790 0.82 ENST00000558791.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr15_+_33010175 0.81 ENST00000300177.4
ENST00000560677.1
ENST00000560830.1
GREM1
gremlin 1, DAN family BMP antagonist
chr3_-_4793274 0.79 ENST00000414938.1
EGOT
eosinophil granule ontogeny transcript (non-protein coding)
chr6_+_29691056 0.78 ENST00000414333.1
ENST00000334668.4
ENST00000259951.7
HLA-F
major histocompatibility complex, class I, F
chr16_+_53242350 0.77 ENST00000565442.1
CHD9
chromodomain helicase DNA binding protein 9
chr10_+_30723533 0.76 ENST00000413724.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr2_+_161993465 0.73 ENST00000457476.1
TANK
TRAF family member-associated NFKB activator
chr14_-_24616426 0.72 ENST00000216802.5
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr3_+_159706537 0.71 ENST00000305579.2
ENST00000480787.1
ENST00000466512.1
IL12A
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
chr11_-_790060 0.69 ENST00000330106.4
CEND1
cell cycle exit and neuronal differentiation 1
chr15_-_66084621 0.69 ENST00000564674.1
DENND4A
DENN/MADD domain containing 4A
chr6_-_31550192 0.62 ENST00000429299.2
ENST00000446745.2
LTB
lymphotoxin beta (TNF superfamily, member 3)
chr5_+_56469843 0.61 ENST00000514387.2
GPBP1
GC-rich promoter binding protein 1
chr15_+_44719970 0.59 ENST00000558966.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr3_-_158390282 0.58 ENST00000264265.3
LXN
latexin
chr14_+_24616588 0.57 ENST00000324103.6
ENST00000559260.1
RNF31
ring finger protein 31
chr9_-_117568365 0.56 ENST00000374045.4
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr1_-_166135952 0.56 ENST00000354422.3
FAM78B
family with sequence similarity 78, member B
chr10_+_86088381 0.56 ENST00000224756.8
ENST00000372088.2
CCSER2
coiled-coil serine-rich protein 2
chr15_+_52311398 0.56 ENST00000261845.5
MAPK6
mitogen-activated protein kinase 6
chr1_+_100818156 0.55 ENST00000336454.3
CDC14A
cell division cycle 14A
chr15_-_71055769 0.55 ENST00000539319.1
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr5_+_56469939 0.54 ENST00000506184.2
GPBP1
GC-rich promoter binding protein 1
chr11_-_113644491 0.52 ENST00000200135.3
ZW10
zw10 kinetochore protein
chr18_-_12884259 0.50 ENST00000353319.4
ENST00000327283.3
PTPN2
protein tyrosine phosphatase, non-receptor type 2
chr1_+_6845578 0.49 ENST00000467404.2
ENST00000439411.2
CAMTA1
calmodulin binding transcription activator 1
chr12_-_117537240 0.49 ENST00000392545.4
ENST00000541210.1
ENST00000335209.7
TESC
tescalcin
chr10_-_7708918 0.48 ENST00000256861.6
ENST00000397146.2
ENST00000446830.2
ENST00000397145.2
ITIH5
inter-alpha-trypsin inhibitor heavy chain family, member 5
chr2_+_64681641 0.48 ENST00000409537.2
LGALSL
lectin, galactoside-binding-like
chr6_+_88299833 0.47 ENST00000392844.3
ENST00000257789.4
ENST00000546266.1
ENST00000417380.2
ORC3
origin recognition complex, subunit 3
chr2_+_162016916 0.47 ENST00000405852.1
TANK
TRAF family member-associated NFKB activator
chr15_-_71055878 0.46 ENST00000322954.6
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chrX_-_131352152 0.46 ENST00000342983.2
RAP2C
RAP2C, member of RAS oncogene family
chr3_+_157154578 0.45 ENST00000295927.3
PTX3
pentraxin 3, long
chr7_+_120629653 0.45 ENST00000450913.2
ENST00000340646.5
CPED1
cadherin-like and PC-esterase domain containing 1
chr4_-_174256276 0.45 ENST00000296503.5
HMGB2
high mobility group box 2
chr2_-_177502659 0.44 ENST00000295549.4
AC017048.3
long intergenic non-protein coding RNA 1116
chr3_+_111578027 0.44 ENST00000431670.2
ENST00000412622.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr2_+_234602305 0.44 ENST00000406651.1
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr7_-_16844611 0.44 ENST00000401412.1
ENST00000419304.2
AGR2
anterior gradient 2
chr13_-_52026730 0.44 ENST00000420668.2
INTS6
integrator complex subunit 6
chr18_-_71959159 0.44 ENST00000494131.2
ENST00000397914.4
ENST00000340533.4
CYB5A
cytochrome b5 type A (microsomal)
chr14_-_53417732 0.44 ENST00000399304.3
ENST00000395631.2
ENST00000341590.3
ENST00000343279.4
FERMT2
fermitin family member 2
chr16_-_53737722 0.44 ENST00000569716.1
ENST00000562588.1
ENST00000562230.1
ENST00000379925.3
ENST00000563746.1
ENST00000568653.3
RPGRIP1L
RPGRIP1-like
chr1_-_245026388 0.43 ENST00000440865.1
HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr14_+_75536280 0.43 ENST00000238686.8
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr11_+_46299199 0.43 ENST00000529193.1
ENST00000288400.3
CREB3L1
cAMP responsive element binding protein 3-like 1
chr9_-_127952187 0.43 ENST00000451402.1
ENST00000415905.1
PPP6C
protein phosphatase 6, catalytic subunit
chr14_-_22005062 0.43 ENST00000317492.5
SALL2
spalt-like transcription factor 2
chr5_+_56469775 0.42 ENST00000424459.3
GPBP1
GC-rich promoter binding protein 1
chr6_+_149638876 0.41 ENST00000392282.1
TAB2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr8_+_38758737 0.41 ENST00000521746.1
ENST00000420274.1
PLEKHA2
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
chr1_+_110453109 0.40 ENST00000525659.1
CSF1
colony stimulating factor 1 (macrophage)
chr14_+_103589789 0.40 ENST00000558056.1
ENST00000560869.1
TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr2_+_61108650 0.40 ENST00000295025.8
REL
v-rel avian reticuloendotheliosis viral oncogene homolog
chr9_+_36572851 0.40 ENST00000298048.2
ENST00000538311.1
ENST00000536987.1
ENST00000545008.1
ENST00000536860.1
ENST00000536329.1
ENST00000541717.1
ENST00000543751.1
MELK
maternal embryonic leucine zipper kinase
chr6_-_24720226 0.39 ENST00000378102.3
C6orf62
chromosome 6 open reading frame 62
chr9_-_130693048 0.39 ENST00000388747.4
PIP5KL1
phosphatidylinositol-4-phosphate 5-kinase-like 1
chr13_+_37581115 0.39 ENST00000481013.1
EXOSC8
exosome component 8
chr16_-_53737795 0.39 ENST00000262135.4
ENST00000564374.1
ENST00000566096.1
RPGRIP1L
RPGRIP1-like
chr1_-_32403903 0.38 ENST00000344035.6
ENST00000356536.3
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr5_+_112312454 0.38 ENST00000543319.1
DCP2
decapping mRNA 2
chr6_-_30712313 0.38 ENST00000376377.2
ENST00000259874.5
IER3
immediate early response 3
chr13_+_97874574 0.38 ENST00000343600.4
ENST00000345429.6
ENST00000376673.3
MBNL2
muscleblind-like splicing regulator 2
chr5_+_118604385 0.38 ENST00000274456.6
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr15_+_57884086 0.38 ENST00000380569.2
ENST00000380561.2
ENST00000574161.1
ENST00000572390.1
ENST00000396180.1
ENST00000380560.2
GCOM1
GRINL1A complex locus 1
chr19_+_10381769 0.38 ENST00000423829.2
ENST00000588645.1
ICAM1
intercellular adhesion molecule 1
chr1_-_220101944 0.38 ENST00000366926.3
ENST00000536992.1
SLC30A10
solute carrier family 30, member 10
chr1_+_100818009 0.38 ENST00000370125.2
ENST00000361544.6
ENST00000370124.3
CDC14A
cell division cycle 14A
chr12_-_56727676 0.37 ENST00000547572.1
ENST00000257931.5
ENST00000440411.3
PAN2
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr8_-_103668114 0.37 ENST00000285407.6
KLF10
Kruppel-like factor 10
chr7_-_93520259 0.37 ENST00000222543.5
TFPI2
tissue factor pathway inhibitor 2
chrX_-_119709637 0.36 ENST00000404115.3
CUL4B
cullin 4B
chr7_-_127032363 0.36 ENST00000393312.1
ZNF800
zinc finger protein 800
chr9_-_125667618 0.36 ENST00000423239.2
RC3H2
ring finger and CCCH-type domains 2
chr5_-_141257954 0.35 ENST00000456271.1
ENST00000394536.3
ENST00000503492.1
ENST00000287008.3
PCDH1
protocadherin 1
chr3_+_111578131 0.35 ENST00000498699.1
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr6_+_32121908 0.34 ENST00000375143.2
ENST00000424499.1
PPT2
palmitoyl-protein thioesterase 2
chr4_+_140222609 0.34 ENST00000296543.5
ENST00000398947.1
NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr18_+_3252265 0.34 ENST00000580887.1
ENST00000536605.1
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr9_+_127615733 0.34 ENST00000373574.1
WDR38
WD repeat domain 38
chr1_+_63833261 0.33 ENST00000371108.4
ALG6
ALG6, alpha-1,3-glucosyltransferase
chr15_+_57884117 0.33 ENST00000267853.5
MYZAP
myocardial zonula adherens protein
chr1_+_235490659 0.33 ENST00000488594.1
GGPS1
geranylgeranyl diphosphate synthase 1
chr2_+_202047843 0.33 ENST00000272879.5
ENST00000374650.3
ENST00000346817.5
ENST00000313728.7
ENST00000448480.1
CASP10
caspase 10, apoptosis-related cysteine peptidase
chr1_-_36615065 0.33 ENST00000373166.3
ENST00000373159.1
ENST00000373162.1
TRAPPC3
trafficking protein particle complex 3
chr2_-_136743039 0.32 ENST00000537273.1
DARS
aspartyl-tRNA synthetase
chr4_-_185395191 0.32 ENST00000510814.1
ENST00000507523.1
ENST00000506230.1
IRF2
interferon regulatory factor 2
chr1_+_100818484 0.32 ENST00000544534.1
CDC14A
cell division cycle 14A
chrX_+_117861535 0.32 ENST00000371666.3
ENST00000371642.1
IL13RA1
interleukin 13 receptor, alpha 1
chr1_+_211432700 0.32 ENST00000452621.2
RCOR3
REST corepressor 3
chr19_+_45251804 0.32 ENST00000164227.5
BCL3
B-cell CLL/lymphoma 3
chr6_+_32121789 0.32 ENST00000437001.2
ENST00000375137.2
PPT2
palmitoyl-protein thioesterase 2
chr17_+_34900737 0.32 ENST00000304718.4
ENST00000485685.2
GGNBP2
gametogenetin binding protein 2
chr6_+_30850862 0.31 ENST00000504651.1
ENST00000512694.1
ENST00000515233.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr1_-_54304212 0.31 ENST00000540001.1
NDC1
NDC1 transmembrane nucleoporin
chr3_-_134369853 0.31 ENST00000508956.1
ENST00000503669.1
ENST00000423778.2
KY
kyphoscoliosis peptidase
chr15_+_57884199 0.31 ENST00000587652.1
ENST00000380568.3
ENST00000380565.4
ENST00000380563.2
GCOM1
MYZAP
POLR2M
GRINL1A complex locus 1
myocardial zonula adherens protein
polymerase (RNA) II (DNA directed) polypeptide M
chr1_+_66820058 0.31 ENST00000480109.2
PDE4B
phosphodiesterase 4B, cAMP-specific
chr12_-_54653313 0.31 ENST00000550411.1
ENST00000439541.2
CBX5
chromobox homolog 5
chr12_+_49761273 0.30 ENST00000551540.1
ENST00000552918.1
ENST00000548777.1
ENST00000547865.1
ENST00000552171.1
SPATS2
spermatogenesis associated, serine-rich 2
chrX_-_21776281 0.30 ENST00000379494.3
SMPX
small muscle protein, X-linked
chr2_+_208394616 0.30 ENST00000432329.2
ENST00000353267.3
ENST00000445803.1
CREB1
cAMP responsive element binding protein 1
chr2_-_136743436 0.30 ENST00000441323.1
ENST00000449218.1
DARS
aspartyl-tRNA synthetase
chr12_+_110718428 0.30 ENST00000552636.1
ATP2A2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr8_+_42128861 0.29 ENST00000518983.1
IKBKB
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
chr4_-_103749105 0.29 ENST00000394801.4
ENST00000394804.2
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr6_-_88299678 0.29 ENST00000369536.5
RARS2
arginyl-tRNA synthetase 2, mitochondrial
chr7_-_93520191 0.28 ENST00000545378.1
TFPI2
tissue factor pathway inhibitor 2
chr14_-_23395623 0.28 ENST00000556043.1
PRMT5
protein arginine methyltransferase 5
chr9_+_19230433 0.28 ENST00000434457.2
ENST00000602925.1
DENND4C
DENN/MADD domain containing 4C
chr15_+_27216530 0.28 ENST00000555083.1
GABRG3
gamma-aminobutyric acid (GABA) A receptor, gamma 3
chr6_+_87865262 0.28 ENST00000369577.3
ENST00000518845.1
ENST00000339907.4
ENST00000496806.2
ZNF292
zinc finger protein 292
chr1_-_54303934 0.28 ENST00000537333.1
NDC1
NDC1 transmembrane nucleoporin
chr6_+_12008986 0.28 ENST00000491710.1
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr1_+_169077133 0.27 ENST00000494797.1
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr5_-_127418573 0.27 ENST00000508353.1
ENST00000508878.1
ENST00000501652.1
ENST00000514409.1
CTC-228N24.3
CTC-228N24.3
chr14_+_96968707 0.27 ENST00000216277.8
ENST00000557320.1
ENST00000557471.1
PAPOLA
poly(A) polymerase alpha
chr21_+_35553045 0.27 ENST00000416145.1
ENST00000430922.1
ENST00000419881.2
LINC00310
long intergenic non-protein coding RNA 310
chr10_+_22605374 0.27 ENST00000448361.1
COMMD3
COMM domain containing 3
chr20_-_43977055 0.26 ENST00000372733.3
ENST00000537976.1
SDC4
syndecan 4
chr14_+_53196872 0.26 ENST00000442123.2
ENST00000354586.4
STYX
serine/threonine/tyrosine interacting protein
chr1_+_169077172 0.26 ENST00000499679.3
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr9_-_125667494 0.26 ENST00000335387.5
ENST00000357244.2
ENST00000373665.2
RC3H2
ring finger and CCCH-type domains 2
chrX_-_20284733 0.26 ENST00000438357.1
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr4_-_103749313 0.26 ENST00000394803.5
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr12_+_49761224 0.25 ENST00000553127.1
ENST00000321898.6
SPATS2
spermatogenesis associated, serine-rich 2
chr5_-_127418755 0.25 ENST00000501702.2
ENST00000501173.2
ENST00000514573.1
ENST00000499346.2
ENST00000606251.1
CTC-228N24.3
CTC-228N24.3
chr21_+_34775772 0.25 ENST00000405436.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr2_-_136743169 0.25 ENST00000264161.4
DARS
aspartyl-tRNA synthetase
chr10_+_124739964 0.25 ENST00000406217.2
PSTK
phosphoseryl-tRNA kinase
chr14_+_61789382 0.25 ENST00000555082.1
PRKCH
protein kinase C, eta
chr2_+_42721689 0.25 ENST00000405592.1
MTA3
metastasis associated 1 family, member 3
chr17_+_46189311 0.25 ENST00000582481.1
SNX11
sorting nexin 11
chr19_+_6740888 0.24 ENST00000596673.1
TRIP10
thyroid hormone receptor interactor 10
chr22_-_28315115 0.24 ENST00000455418.3
ENST00000436663.1
ENST00000320996.10
ENST00000335272.5
PITPNB
phosphatidylinositol transfer protein, beta
chr1_+_151171012 0.24 ENST00000349792.5
ENST00000409426.1
ENST00000441902.2
ENST00000368890.4
ENST00000424999.1
ENST00000368888.4
PIP5K1A
phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
chr9_-_127952032 0.24 ENST00000456642.1
ENST00000373546.3
ENST00000373547.4
PPP6C
protein phosphatase 6, catalytic subunit
chr3_+_197518100 0.24 ENST00000438796.2
ENST00000414675.2
ENST00000441090.2
ENST00000334859.4
ENST00000425562.2
LRCH3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr4_+_41614720 0.24 ENST00000509277.1
LIMCH1
LIM and calponin homology domains 1
chr1_-_203274387 0.24 ENST00000432511.1
RP11-134P9.1
long intergenic non-protein coding RNA 1136
chr2_+_219745020 0.24 ENST00000258411.3
WNT10A
wingless-type MMTV integration site family, member 10A
chr15_-_50978965 0.23 ENST00000560955.1
ENST00000313478.7
TRPM7
transient receptor potential cation channel, subfamily M, member 7
chr14_+_75988768 0.23 ENST00000286639.6
BATF
basic leucine zipper transcription factor, ATF-like
chr1_-_202129704 0.23 ENST00000476061.1
ENST00000544762.1
ENST00000467283.1
ENST00000464870.1
ENST00000435759.2
ENST00000486116.1
ENST00000543735.1
ENST00000308986.5
ENST00000477625.1
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr8_+_38758845 0.23 ENST00000519640.1
PLEKHA2
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
chr10_+_18948311 0.23 ENST00000377275.3
ARL5B
ADP-ribosylation factor-like 5B
chr6_+_33378517 0.23 ENST00000428274.1
PHF1
PHD finger protein 1
chr5_-_58652788 0.23 ENST00000405755.2
PDE4D
phosphodiesterase 4D, cAMP-specific
chr2_+_44396000 0.23 ENST00000409895.4
ENST00000409432.3
ENST00000282412.4
ENST00000378551.2
ENST00000345249.4
PPM1B
protein phosphatase, Mg2+/Mn2+ dependent, 1B
chr6_-_150039170 0.22 ENST00000458696.2
ENST00000392273.3
LATS1
large tumor suppressor kinase 1
chr3_+_52280220 0.22 ENST00000409502.3
ENST00000323588.4
PPM1M
protein phosphatase, Mg2+/Mn2+ dependent, 1M
chr15_+_27216297 0.22 ENST00000333743.6
GABRG3
gamma-aminobutyric acid (GABA) A receptor, gamma 3
chr9_+_97562440 0.22 ENST00000395357.2
C9orf3
chromosome 9 open reading frame 3
chr1_+_89990431 0.21 ENST00000330947.2
ENST00000358200.4
LRRC8B
leucine rich repeat containing 8 family, member B
chr16_+_50775948 0.21 ENST00000569681.1
ENST00000569418.1
ENST00000540145.1
CYLD
cylindromatosis (turban tumor syndrome)
chr1_-_54303949 0.20 ENST00000234725.8
NDC1
NDC1 transmembrane nucleoporin
chr15_+_42066888 0.20 ENST00000510535.1
MAPKBP1
mitogen-activated protein kinase binding protein 1
chr11_-_57194111 0.19 ENST00000529112.1
ENST00000529896.1
SLC43A3
solute carrier family 43, member 3

Network of associatons between targets according to the STRING database.

First level regulatory network of RELA

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.9 GO:2000349 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of CD40 signaling pathway(GO:2000349)
1.2 5.0 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.7 2.0 GO:0042222 interleukin-1 biosynthetic process(GO:0042222) regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.5 1.9 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.4 2.2 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.4 0.8 GO:0090291 negative regulation of osteoclast proliferation(GO:0090291)
0.4 1.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.3 8.7 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.3 1.5 GO:0001878 response to yeast(GO:0001878)
0.3 0.9 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.3 0.8 GO:0071790 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.3 2.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.2 2.2 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.2 0.9 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.2 1.8 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.2 0.5 GO:1902232 regulation of positive thymic T cell selection(GO:1902232)
0.2 0.5 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 1.3 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.9 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.6 GO:0023035 CD40 signaling pathway(GO:0023035)
0.1 0.3 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
0.1 0.3 GO:0045082 positive regulation of interleukin-10 biosynthetic process(GO:0045082)
0.1 0.3 GO:0051685 maintenance of ER location(GO:0051685)
0.1 0.6 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 0.7 GO:2000510 regulation of dendritic cell chemotaxis(GO:2000508) positive regulation of dendritic cell chemotaxis(GO:2000510)
0.1 0.7 GO:0021590 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.1 0.3 GO:1903515 calcium ion transport from cytosol to endoplasmic reticulum(GO:1903515)
0.1 0.4 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.1 0.3 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.4 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.1 0.8 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 0.2 GO:0045210 FasL biosynthetic process(GO:0045210)
0.1 0.3 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1 0.2 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.1 0.4 GO:0001827 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.1 0.5 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.1 0.9 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.1 0.2 GO:1990108 protein linear deubiquitination(GO:1990108)
0.1 0.6 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.1 1.3 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.2 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.4 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 2.2 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 0.2 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.1 0.3 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.1 4.8 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 1.4 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 1.7 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716)
0.0 1.3 GO:0016180 snRNA processing(GO:0016180)
0.0 0.3 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.3 GO:0060161 positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.0 0.2 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.7 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.7 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.8 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.4 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.0 0.4 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.4 GO:0034350 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.3 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.6 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.4 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.6 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.4 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.2 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.5 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.1 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.0 0.1 GO:1903613 regulation of protein tyrosine phosphatase activity(GO:1903613) positive regulation of protein tyrosine phosphatase activity(GO:1903615)
0.0 0.2 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 2.5 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.6 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.0 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.1 GO:1904617 regulation of actin filament binding(GO:1904529) negative regulation of actin filament binding(GO:1904530) regulation of actin binding(GO:1904616) negative regulation of actin binding(GO:1904617)
0.0 0.1 GO:0001826 inner cell mass cell differentiation(GO:0001826)
0.0 0.2 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.8 GO:0060039 pericardium development(GO:0060039)
0.0 0.4 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.2 GO:0097056 selenocysteinyl-tRNA(Sec) biosynthetic process(GO:0097056)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 0.4 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.2 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.0 0.1 GO:0045083 negative regulation of interleukin-12 biosynthetic process(GO:0045083)
0.0 0.2 GO:0033216 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.6 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 0.1 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.4 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.2 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.3 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.4 GO:0033622 integrin activation(GO:0033622)
0.0 0.2 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 1.2 GO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway(GO:0007193)
0.0 0.2 GO:0038171 cannabinoid signaling pathway(GO:0038171)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242) negative regulation of myoblast fusion(GO:1901740)
0.0 0.4 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.6 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.3 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.1 GO:0061469 response to corticotropin-releasing hormone(GO:0043435) regulation of type B pancreatic cell proliferation(GO:0061469) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.2 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.3 0.8 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.2 0.8 GO:0005879 axonemal microtubule(GO:0005879)
0.2 1.8 GO:0042612 MHC class I protein complex(GO:0042612)
0.2 0.5 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.1 0.5 GO:1990423 Dsl1p complex(GO:0070939) RZZ complex(GO:1990423)
0.1 0.5 GO:0031251 PAN complex(GO:0031251)
0.1 0.7 GO:0008537 proteasome activator complex(GO:0008537)
0.1 1.7 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 1.4 GO:0060091 kinocilium(GO:0060091)
0.1 0.6 GO:0071797 LUBAC complex(GO:0071797)
0.1 1.3 GO:0032039 integrator complex(GO:0032039)
0.1 0.7 GO:0031906 late endosome lumen(GO:0031906)
0.1 1.9 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.3 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.3 GO:0031415 NatA complex(GO:0031415)
0.0 0.9 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.4 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 0.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.4 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 2.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.8 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.5 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.3 GO:0097470 ribbon synapse(GO:0097470)
0.0 0.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.7 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.3 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.6 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.2 GO:0001726 ruffle(GO:0001726)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.8 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 2.0 GO:0032587 ruffle membrane(GO:0032587)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 10.6 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.7 2.0 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.5 1.4 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.3 1.1 GO:0001601 peptide YY receptor activity(GO:0001601)
0.3 0.8 GO:0031862 prostanoid receptor binding(GO:0031862)
0.3 5.1 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.3 2.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.2 1.6 GO:0046979 TAP2 binding(GO:0046979)
0.2 0.9 GO:0019981 interleukin-6 receptor activity(GO:0004915) leukemia inhibitory factor receptor activity(GO:0004923) interleukin-6 binding(GO:0019981)
0.2 1.1 GO:0050473 prostaglandin-endoperoxide synthase activity(GO:0004666) arachidonate 15-lipoxygenase activity(GO:0050473)
0.2 0.9 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.2 1.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 0.9 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 5.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.7 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.5 GO:0097677 STAT family protein binding(GO:0097677)
0.1 0.3 GO:0031775 lutropin-choriogonadotropic hormone receptor binding(GO:0031775) calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential(GO:0086039)
0.1 0.4 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 0.4 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.1 0.3 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.1 0.2 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.1 0.8 GO:0016015 morphogen activity(GO:0016015)
0.1 0.3 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.1 0.4 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 0.4 GO:0001849 complement component C1q binding(GO:0001849)
0.1 2.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 2.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.4 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.4 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.3 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.5 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.7 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 2.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 1.9 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.3 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.3 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.8 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 4.6 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.2 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.4 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.3 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.2 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.5 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 0.2 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 1.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0031014 troponin T binding(GO:0031014)
0.0 0.2 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.4 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.0 0.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 1.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.6 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.4 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 3.0 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.4 GO:0004532 exoribonuclease activity(GO:0004532)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.0 GO:0004779 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.0 0.1 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.2 GO:0071837 HMG box domain binding(GO:0071837)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.9 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.2 2.0 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 8.0 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 3.0 PID IL27 PATHWAY IL27-mediated signaling events
0.1 0.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 2.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 2.6 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 1.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.1 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.5 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.1 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.8 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 9.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.4 ST ADRENERGIC Adrenergic Pathway
0.0 0.9 PID BMP PATHWAY BMP receptor signaling
0.0 0.7 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.6 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.3 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 13.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 4.9 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.2 4.0 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.2 2.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.2 1.8 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 2.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 7.8 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 5.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 0.4 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 1.9 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.9 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 1.3 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.5 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.4 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.9 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.1 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 1.3 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.3 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 0.4 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.3 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein