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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for REL

Z-value: 0.83

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Transcription factors associated with REL

Gene Symbol Gene ID Gene Info
REL
ENSG00000162924.9 REL proto-oncogene, NF-kB subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
RELhg19_v2_chr2_+_61108771_611087910.463.6e-01Click!

Activity profile of REL motif

Sorted Z-values of REL motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr22_+_46546406 1.18 ENST00000440343.1
ENST00000415785.1
PPARA
peroxisome proliferator-activated receptor alpha
chr1_+_6845578 0.75 ENST00000467404.2
ENST00000439411.2
CAMTA1
calmodulin binding transcription activator 1
chr19_+_58193388 0.61 ENST00000596085.1
ENST00000594684.1
ZNF551
AC003006.7
zinc finger protein 551
Uncharacterized protein
chr15_+_44719996 0.54 ENST00000559793.1
ENST00000558968.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr17_-_15469590 0.53 ENST00000312127.2
CDRT1
CMT duplicated region transcript 1; Uncharacterized protein
chr20_-_36156264 0.52 ENST00000445723.1
ENST00000414080.1
BLCAP
bladder cancer associated protein
chr22_-_28490123 0.45 ENST00000442232.1
TTC28
tetratricopeptide repeat domain 28
chr19_-_4338783 0.45 ENST00000601482.1
ENST00000600324.1
STAP2
signal transducing adaptor family member 2
chr6_-_30080863 0.43 ENST00000540829.1
TRIM31
tripartite motif containing 31
chr4_-_185395191 0.42 ENST00000510814.1
ENST00000507523.1
ENST00000506230.1
IRF2
interferon regulatory factor 2
chr3_+_169629354 0.41 ENST00000428432.2
ENST00000335556.3
SAMD7
sterile alpha motif domain containing 7
chr6_+_138188351 0.41 ENST00000421450.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr16_+_84209539 0.41 ENST00000569735.1
DNAAF1
dynein, axonemal, assembly factor 1
chr14_-_103589246 0.41 ENST00000558224.1
ENST00000560742.1
LINC00677
long intergenic non-protein coding RNA 677
chr4_+_74702214 0.41 ENST00000226317.5
ENST00000515050.1
CXCL6
chemokine (C-X-C motif) ligand 6
chr2_-_191885686 0.40 ENST00000432058.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr1_+_6845497 0.40 ENST00000473578.1
ENST00000557126.1
CAMTA1
calmodulin binding transcription activator 1
chr6_-_30080876 0.38 ENST00000376734.3
TRIM31
tripartite motif containing 31
chr2_+_208394658 0.36 ENST00000421139.1
CREB1
cAMP responsive element binding protein 1
chr22_+_22676808 0.36 ENST00000390290.2
IGLV1-51
immunoglobulin lambda variable 1-51
chr4_+_74735102 0.32 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr14_+_37667230 0.32 ENST00000556451.1
ENST00000556753.1
ENST00000396294.2
MIPOL1
mirror-image polydactyly 1
chr17_-_4642429 0.31 ENST00000573123.1
CXCL16
chemokine (C-X-C motif) ligand 16
chr12_-_95009837 0.31 ENST00000551457.1
TMCC3
transmembrane and coiled-coil domain family 3
chr2_+_208394616 0.31 ENST00000432329.2
ENST00000353267.3
ENST00000445803.1
CREB1
cAMP responsive element binding protein 1
chr1_-_205912577 0.30 ENST00000367135.3
ENST00000367134.2
SLC26A9
solute carrier family 26 (anion exchanger), member 9
chr4_+_185395947 0.30 ENST00000605834.1
RP11-326I11.3
RP11-326I11.3
chr5_+_118604439 0.27 ENST00000388882.5
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr9_+_101705893 0.27 ENST00000375001.3
COL15A1
collagen, type XV, alpha 1
chr10_+_89124746 0.27 ENST00000465545.1
NUTM2D
NUT family member 2D
chr13_-_88323514 0.26 ENST00000441617.1
MIR4500HG
MIR4500 host gene (non-protein coding)
chr10_+_30723105 0.26 ENST00000375322.2
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr8_-_101321584 0.26 ENST00000523167.1
RNF19A
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr5_-_127418573 0.25 ENST00000508353.1
ENST00000508878.1
ENST00000501652.1
ENST00000514409.1
CTC-228N24.3
CTC-228N24.3
chr19_+_58193337 0.25 ENST00000601064.1
ENST00000282296.5
ENST00000356715.4
ZNF551
zinc finger protein 551
chr2_-_113594279 0.25 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B
interleukin 1, beta
chr3_-_179322436 0.25 ENST00000392659.2
ENST00000476781.1
MRPL47
mitochondrial ribosomal protein L47
chr2_-_204400113 0.25 ENST00000319170.5
RAPH1
Ras association (RalGDS/AF-6) and pleckstrin homology domains 1
chr10_-_91295304 0.25 ENST00000341233.4
ENST00000371790.4
SLC16A12
solute carrier family 16, member 12
chr11_+_46316677 0.25 ENST00000534787.1
CREB3L1
cAMP responsive element binding protein 3-like 1
chr20_+_43803517 0.22 ENST00000243924.3
PI3
peptidase inhibitor 3, skin-derived
chr7_-_99679324 0.22 ENST00000292393.5
ENST00000413658.2
ENST00000412947.1
ENST00000441298.1
ENST00000449785.1
ENST00000299667.4
ENST00000424697.1
ZNF3
zinc finger protein 3
chr7_-_102252589 0.22 ENST00000520042.1
RASA4
RAS p21 protein activator 4
chr11_+_102188272 0.20 ENST00000532808.1
BIRC3
baculoviral IAP repeat containing 3
chr2_-_128145498 0.20 ENST00000409179.2
MAP3K2
mitogen-activated protein kinase kinase kinase 2
chr7_+_107384579 0.20 ENST00000222597.2
ENST00000415884.2
CBLL1
Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase
chr6_-_143832820 0.20 ENST00000002165.6
FUCA2
fucosidase, alpha-L- 2, plasma
chr4_-_176733897 0.20 ENST00000393658.2
GPM6A
glycoprotein M6A
chr10_+_90750493 0.19 ENST00000357339.2
ENST00000355279.2
FAS
Fas cell surface death receptor
chr19_-_49250054 0.19 ENST00000602105.1
ENST00000332955.2
IZUMO1
izumo sperm-egg fusion 1
chr2_+_208394794 0.19 ENST00000536726.1
ENST00000374397.4
ENST00000452474.1
CREB1
cAMP responsive element binding protein 1
chr15_+_33010175 0.19 ENST00000300177.4
ENST00000560677.1
ENST00000560830.1
GREM1
gremlin 1, DAN family BMP antagonist
chr11_+_102188224 0.19 ENST00000263464.3
BIRC3
baculoviral IAP repeat containing 3
chrX_-_20284733 0.19 ENST00000438357.1
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr1_-_62190793 0.19 ENST00000371177.2
ENST00000606498.1
TM2D1
TM2 domain containing 1
chr2_+_238600933 0.19 ENST00000420665.1
ENST00000392000.4
LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
chr12_-_86230315 0.19 ENST00000361228.3
RASSF9
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr3_-_179322416 0.18 ENST00000259038.2
MRPL47
mitochondrial ribosomal protein L47
chr4_-_74904398 0.17 ENST00000296026.4
CXCL3
chemokine (C-X-C motif) ligand 3
chr4_+_114214125 0.17 ENST00000509550.1
ANK2
ankyrin 2, neuronal
chr2_+_202047843 0.17 ENST00000272879.5
ENST00000374650.3
ENST00000346817.5
ENST00000313728.7
ENST00000448480.1
CASP10
caspase 10, apoptosis-related cysteine peptidase
chr11_-_75062730 0.16 ENST00000420843.2
ENST00000360025.3
ARRB1
arrestin, beta 1
chr4_-_146101304 0.16 ENST00000447906.2
OTUD4
OTU domain containing 4
chr3_+_52719936 0.16 ENST00000418458.1
ENST00000394799.2
GNL3
guanine nucleotide binding protein-like 3 (nucleolar)
chr5_-_59064458 0.16 ENST00000502575.1
ENST00000507116.1
PDE4D
phosphodiesterase 4D, cAMP-specific
chr10_+_30723045 0.15 ENST00000542547.1
ENST00000415139.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr19_-_39390212 0.15 ENST00000437828.1
SIRT2
sirtuin 2
chr11_-_75062829 0.15 ENST00000393505.4
ARRB1
arrestin, beta 1
chr4_-_76957214 0.15 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr3_+_197518100 0.15 ENST00000438796.2
ENST00000414675.2
ENST00000441090.2
ENST00000334859.4
ENST00000425562.2
LRCH3
leucine-rich repeats and calponin homology (CH) domain containing 3
chr10_-_6104253 0.15 ENST00000256876.6
ENST00000379954.1
ENST00000379959.3
IL2RA
interleukin 2 receptor, alpha
chr2_-_61108449 0.15 ENST00000439412.1
ENST00000452343.1
AC010733.4
AC010733.4
chr2_-_113993020 0.15 ENST00000465084.1
PAX8
paired box 8
chr1_-_23694794 0.15 ENST00000374608.3
ZNF436
zinc finger protein 436
chr13_+_95364963 0.14 ENST00000438290.2
SOX21-AS1
SOX21 antisense RNA 1 (head to head)
chr18_+_3252265 0.14 ENST00000580887.1
ENST00000536605.1
MYL12A
myosin, light chain 12A, regulatory, non-sarcomeric
chr12_+_102271129 0.14 ENST00000258534.8
DRAM1
DNA-damage regulated autophagy modulator 1
chr22_+_46731676 0.14 ENST00000424260.2
TRMU
tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
chr12_-_56211485 0.14 ENST00000552080.1
ENST00000444631.2
ENST00000336133.3
SARNP
SAP domain containing ribonucleoprotein
chr8_+_144816303 0.14 ENST00000533004.1
FAM83H-AS1
FAM83H antisense RNA 1 (head to head)
chr1_+_95582881 0.14 ENST00000370203.4
ENST00000456991.1
TMEM56
transmembrane protein 56
chr15_+_71145578 0.14 ENST00000544974.2
ENST00000558546.1
LRRC49
leucine rich repeat containing 49
chr22_+_46731596 0.13 ENST00000381019.3
TRMU
tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
chr10_+_22614547 0.13 ENST00000416820.1
BMI1
BMI1 polycomb ring finger oncogene
chr1_-_27216729 0.13 ENST00000431781.2
ENST00000374135.4
GPN2
GPN-loop GTPase 2
chr3_+_184081137 0.13 ENST00000443489.1
POLR2H
polymerase (RNA) II (DNA directed) polypeptide H
chr2_+_204193101 0.13 ENST00000430418.1
ENST00000424558.1
ENST00000261016.6
ABI2
abl-interactor 2
chr10_-_46970533 0.13 ENST00000512997.1
SYT15
synaptotagmin XV
chr2_+_202047596 0.13 ENST00000286186.6
ENST00000360132.3
CASP10
caspase 10, apoptosis-related cysteine peptidase
chr4_-_74864386 0.13 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr2_-_43453734 0.13 ENST00000282388.3
ZFP36L2
ZFP36 ring finger protein-like 2
chr2_+_208394455 0.13 ENST00000430624.1
CREB1
cAMP responsive element binding protein 1
chr6_+_30850862 0.12 ENST00000504651.1
ENST00000512694.1
ENST00000515233.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr17_-_8286484 0.12 ENST00000582556.1
ENST00000584164.1
ENST00000293842.5
ENST00000584343.1
ENST00000578812.1
ENST00000583011.1
RPL26
ribosomal protein L26
chr3_-_139108475 0.12 ENST00000515006.1
ENST00000513274.1
ENST00000514508.1
ENST00000507777.1
ENST00000512153.1
ENST00000333188.5
COPB2
coatomer protein complex, subunit beta 2 (beta prime)
chr20_-_44937124 0.12 ENST00000537909.1
CDH22
cadherin 22, type 2
chr19_+_11466062 0.12 ENST00000251473.5
ENST00000591329.1
ENST00000586380.1
DKFZP761J1410
Lipid phosphate phosphatase-related protein type 2
chr6_-_166075557 0.12 ENST00000539869.2
ENST00000366882.1
PDE10A
phosphodiesterase 10A
chr2_-_88355241 0.12 ENST00000347055.3
KRCC1
lysine-rich coiled-coil 1
chr3_+_141596371 0.12 ENST00000495216.1
ATP1B3
ATPase, Na+/K+ transporting, beta 3 polypeptide
chr8_+_42128861 0.12 ENST00000518983.1
IKBKB
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
chr6_-_32122106 0.11 ENST00000428778.1
PRRT1
proline-rich transmembrane protein 1
chr22_-_41252962 0.11 ENST00000216218.3
ST13
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
chr11_-_64570706 0.11 ENST00000294066.2
ENST00000377350.3
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chr12_-_53297432 0.11 ENST00000546900.1
KRT8
keratin 8
chr14_+_77648167 0.11 ENST00000554346.1
ENST00000298351.4
TMEM63C
transmembrane protein 63C
chr17_-_73178599 0.11 ENST00000578238.1
SUMO2
small ubiquitin-like modifier 2
chr2_+_228189941 0.11 ENST00000353339.3
ENST00000354503.6
ENST00000530359.1
ENST00000531278.1
ENST00000409565.1
ENST00000452930.1
ENST00000409616.1
ENST00000337110.7
ENST00000525195.1
ENST00000534203.1
ENST00000524634.1
ENST00000349901.7
MFF
mitochondrial fission factor
chr10_-_105437909 0.11 ENST00000540321.1
SH3PXD2A
SH3 and PX domains 2A
chr14_+_68086515 0.11 ENST00000261783.3
ARG2
arginase 2
chr12_-_96793142 0.11 ENST00000552262.1
ENST00000551816.1
ENST00000552496.1
CDK17
cyclin-dependent kinase 17
chr14_-_35873856 0.11 ENST00000553342.1
ENST00000216797.5
ENST00000557140.1
NFKBIA
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr10_+_30722866 0.11 ENST00000263056.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr2_+_102314161 0.11 ENST00000425019.1
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr9_-_115480303 0.11 ENST00000374234.1
ENST00000374238.1
ENST00000374236.1
ENST00000374242.4
INIP
INTS3 and NABP interacting protein
chr17_-_45266542 0.10 ENST00000531206.1
ENST00000527547.1
ENST00000446365.2
ENST00000575483.1
ENST00000066544.3
CDC27
cell division cycle 27
chr12_-_77272765 0.10 ENST00000547435.1
ENST00000552330.1
ENST00000546966.1
ENST00000311083.5
CSRP2
cysteine and glycine-rich protein 2
chr2_-_18741882 0.10 ENST00000381249.3
RDH14
retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
chr21_-_34915147 0.10 ENST00000381831.3
ENST00000381839.3
GART
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chr1_-_35658736 0.10 ENST00000357214.5
SFPQ
splicing factor proline/glutamine-rich
chr18_+_33877654 0.10 ENST00000257209.4
ENST00000445677.1
ENST00000590592.1
ENST00000359247.4
FHOD3
formin homology 2 domain containing 3
chr11_-_72852958 0.10 ENST00000458644.2
FCHSD2
FCH and double SH3 domains 2
chr9_-_13279406 0.10 ENST00000546205.1
MPDZ
multiple PDZ domain protein
chr3_-_119379719 0.10 ENST00000493094.1
POPDC2
popeye domain containing 2
chr19_-_17958771 0.10 ENST00000534444.1
JAK3
Janus kinase 3
chr1_+_56880606 0.10 ENST00000451914.1
RP4-710M16.2
RP4-710M16.2
chr11_+_46299199 0.10 ENST00000529193.1
ENST00000288400.3
CREB3L1
cAMP responsive element binding protein 3-like 1
chr17_-_75878647 0.10 ENST00000374983.2
FLJ45079
FLJ45079
chr19_+_35940486 0.10 ENST00000246549.2
FFAR2
free fatty acid receptor 2
chr14_-_24616426 0.09 ENST00000216802.5
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr11_+_120255997 0.09 ENST00000532993.1
ARHGEF12
Rho guanine nucleotide exchange factor (GEF) 12
chr7_-_102715263 0.09 ENST00000379305.3
FBXL13
F-box and leucine-rich repeat protein 13
chr1_-_8000872 0.09 ENST00000377507.3
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr9_+_127054254 0.09 ENST00000422297.1
NEK6
NIMA-related kinase 6
chr13_-_52027134 0.09 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6
integrator complex subunit 6
chr9_-_34637806 0.09 ENST00000477726.1
SIGMAR1
sigma non-opioid intracellular receptor 1
chr17_+_40985407 0.09 ENST00000586114.1
ENST00000590720.1
ENST00000585805.1
ENST00000541124.1
ENST00000441946.2
ENST00000591152.1
ENST00000589469.1
ENST00000293362.3
ENST00000592169.1
PSME3
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr1_-_226595648 0.09 ENST00000366790.3
PARP1
poly (ADP-ribose) polymerase 1
chr19_-_6591113 0.09 ENST00000423145.3
ENST00000245903.3
CD70
CD70 molecule
chr16_+_50730910 0.09 ENST00000300589.2
NOD2
nucleotide-binding oligomerization domain containing 2
chr16_+_3014217 0.09 ENST00000572045.1
KREMEN2
kringle containing transmembrane protein 2
chr1_-_204380919 0.09 ENST00000367188.4
PPP1R15B
protein phosphatase 1, regulatory subunit 15B
chr17_-_16118835 0.09 ENST00000582357.1
ENST00000436828.1
ENST00000411510.1
ENST00000268712.3
NCOR1
nuclear receptor corepressor 1
chr6_+_30850697 0.09 ENST00000509639.1
ENST00000412274.2
ENST00000507901.1
ENST00000507046.1
ENST00000437124.2
ENST00000454612.2
ENST00000396342.2
DDR1
discoidin domain receptor tyrosine kinase 1
chr1_-_27816556 0.09 ENST00000536657.1
WASF2
WAS protein family, member 2
chr9_-_115095229 0.09 ENST00000210227.4
PTBP3
polypyrimidine tract binding protein 3
chr8_+_72755796 0.08 ENST00000524152.1
RP11-383H13.1
Protein LOC100132891; cDNA FLJ53548
chr20_+_42984330 0.08 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
HNF4A
hepatocyte nuclear factor 4, alpha
chr2_+_220094657 0.08 ENST00000436226.1
ANKZF1
ankyrin repeat and zinc finger domain containing 1
chr21_-_34915084 0.08 ENST00000426819.1
GART
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chr5_+_82767284 0.08 ENST00000265077.3
VCAN
versican
chr17_+_49337881 0.08 ENST00000225298.7
UTP18
UTP18 small subunit (SSU) processome component homolog (yeast)
chr12_-_57023995 0.08 ENST00000549884.1
ENST00000546695.1
BAZ2A
bromodomain adjacent to zinc finger domain, 2A
chr5_-_141703713 0.08 ENST00000511815.1
SPRY4
sprouty homolog 4 (Drosophila)
chr18_+_21529811 0.08 ENST00000588004.1
LAMA3
laminin, alpha 3
chr12_+_51632508 0.08 ENST00000449723.3
DAZAP2
DAZ associated protein 2
chr6_-_32821599 0.08 ENST00000354258.4
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr15_-_51914810 0.07 ENST00000543779.2
ENST00000449909.3
DMXL2
Dmx-like 2
chr4_-_185395672 0.07 ENST00000393593.3
IRF2
interferon regulatory factor 2
chr9_+_130911770 0.07 ENST00000372998.1
LCN2
lipocalin 2
chr2_+_204193129 0.07 ENST00000417864.1
ABI2
abl-interactor 2
chr17_-_6338472 0.07 ENST00000570466.1
ENST00000576776.1
ENST00000576307.1
ENST00000381129.3
ENST00000250087.5
AIPL1
aryl hydrocarbon receptor interacting protein-like 1
chr2_+_204192942 0.07 ENST00000295851.5
ENST00000261017.5
ABI2
abl-interactor 2
chr16_-_15736953 0.07 ENST00000548025.1
ENST00000551742.1
ENST00000602337.1
ENST00000344181.3
ENST00000396368.3
KIAA0430
KIAA0430
chr3_-_139108463 0.07 ENST00000512242.1
COPB2
coatomer protein complex, subunit beta 2 (beta prime)
chr2_+_173940668 0.07 ENST00000375213.3
MLTK
Mitogen-activated protein kinase kinase kinase MLT
chr11_+_7597639 0.07 ENST00000533792.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr9_-_115095883 0.07 ENST00000450374.1
ENST00000374255.2
ENST00000334318.6
ENST00000374257.1
PTBP3
polypyrimidine tract binding protein 3
chr11_-_72492903 0.07 ENST00000537947.1
STARD10
StAR-related lipid transfer (START) domain containing 10
chr19_-_47734448 0.07 ENST00000439096.2
BBC3
BCL2 binding component 3
chr6_-_30710265 0.07 ENST00000438162.1
ENST00000454845.1
FLOT1
flotillin 1
chr21_+_34775772 0.07 ENST00000405436.1
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr2_+_204193149 0.07 ENST00000422511.2
ABI2
abl-interactor 2
chr5_-_55290773 0.07 ENST00000502326.3
ENST00000381298.2
IL6ST
interleukin 6 signal transducer (gp130, oncostatin M receptor)
chr3_-_156878540 0.07 ENST00000461804.1
CCNL1
cyclin L1
chr14_-_30396802 0.07 ENST00000415220.2
PRKD1
protein kinase D1
chr3_+_179322573 0.07 ENST00000493866.1
ENST00000472629.1
ENST00000482604.1
NDUFB5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa
chr2_+_162016827 0.07 ENST00000429217.1
ENST00000406287.1
ENST00000402568.1
TANK
TRAF family member-associated NFKB activator
chr1_+_235530675 0.07 ENST00000366601.3
ENST00000406207.1
ENST00000543662.1
TBCE
tubulin folding cofactor E
chr9_+_130911723 0.07 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2
lipocalin 2
chr12_-_117537240 0.06 ENST00000392545.4
ENST00000541210.1
ENST00000335209.7
TESC
tescalcin
chr14_+_37667193 0.06 ENST00000539062.2
MIPOL1
mirror-image polydactyly 1
chr1_+_165796753 0.06 ENST00000367879.4
UCK2
uridine-cytidine kinase 2
chr19_-_4338838 0.06 ENST00000594605.1
STAP2
signal transducing adaptor family member 2
chr15_+_85923856 0.06 ENST00000560302.1
ENST00000394518.2
ENST00000361243.2
ENST00000560256.1
AKAP13
A kinase (PRKA) anchor protein 13
chr19_+_39390320 0.06 ENST00000576510.1
NFKBIB
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr2_+_201987200 0.06 ENST00000425030.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr1_-_151431647 0.06 ENST00000368863.2
ENST00000409503.1
ENST00000491586.1
ENST00000533351.1
ENST00000540984.1
POGZ
pogo transposable element with ZNF domain
chr11_-_64856497 0.06 ENST00000524632.1
ENST00000530719.1
AP003068.6
transmembrane protein 262
chr2_-_163175133 0.06 ENST00000421365.2
ENST00000263642.2
IFIH1
interferon induced with helicase C domain 1
chr4_-_134070250 0.06 ENST00000505289.1
ENST00000509715.1
RP11-9G1.3
RP11-9G1.3
chr11_-_65381643 0.06 ENST00000309100.3
ENST00000529839.1
ENST00000526293.1
MAP3K11
mitogen-activated protein kinase kinase kinase 11
chr2_+_162016916 0.06 ENST00000405852.1
TANK
TRAF family member-associated NFKB activator
chr2_+_220094479 0.06 ENST00000323348.5
ENST00000453432.1
ENST00000409849.1
ENST00000416565.1
ENST00000410034.3
ENST00000447157.1
ANKZF1
ankyrin repeat and zinc finger domain containing 1
chr1_-_32229934 0.06 ENST00000398542.1
BAI2
brain-specific angiogenesis inhibitor 2
chr11_+_65479462 0.06 ENST00000377046.3
ENST00000352980.4
ENST00000341318.4
KAT5
K(lysine) acetyltransferase 5
chr19_-_41256207 0.06 ENST00000598485.2
ENST00000470681.1
ENST00000339153.3
ENST00000598729.1
C19orf54
chromosome 19 open reading frame 54
chr11_+_119039069 0.06 ENST00000422249.1
NLRX1
NLR family member X1
chr3_+_101280677 0.06 ENST00000309922.6
ENST00000495642.1
TRMT10C
tRNA methyltransferase 10 homolog C (S. cerevisiae)
chr11_+_63997750 0.06 ENST00000321685.3
DNAJC4
DnaJ (Hsp40) homolog, subfamily C, member 4

Network of associatons between targets according to the STRING database.

First level regulatory network of REL

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0072361 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.1 1.0 GO:1904550 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.1 0.4 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.1 0.4 GO:0090291 negative regulation of osteoclast proliferation(GO:0090291)
0.1 0.2 GO:0015881 creatine transport(GO:0015881) creatine transmembrane transport(GO:1902598)
0.1 0.3 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.1 0.3 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.1 GO:2000612 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.0 0.1 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 0.1 GO:0045210 FasL biosynthetic process(GO:0045210)
0.0 0.1 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.4 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.0 0.3 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.0 0.2 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.3 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.0 0.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.1 GO:0061433 cellular response to caloric restriction(GO:0061433) negative regulation of oligodendrocyte progenitor proliferation(GO:0070446)
0.0 0.1 GO:0002232 leukocyte chemotaxis involved in inflammatory response(GO:0002232)
0.0 0.1 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 0.2 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.1 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.8 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.6 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.2 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.0 0.3 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.0 0.2 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.0 0.1 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.0 0.1 GO:0061083 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.1 GO:0046967 cytosol to ER transport(GO:0046967)
0.0 0.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.1 GO:2001183 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.1 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:1902231 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164) positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.0 0.1 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.1 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.0 0.0 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.0 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 1.2 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.0 0.2 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.1 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.0 0.1 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:0007620 copulation(GO:0007620)
0.0 0.2 GO:0010818 T cell chemotaxis(GO:0010818)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.2 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.3 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 0.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 0.5 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.4 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.0 GO:0070288 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.0 GO:0098855 HCN channel complex(GO:0098855)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:1990763 arrestin family protein binding(GO:1990763)
0.1 0.3 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 1.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 1.2 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.2 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.1 0.2 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.0 0.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.1 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.0 0.1 GO:0004644 phosphoribosylamine-glycine ligase activity(GO:0004637) phosphoribosylformylglycinamidine cyclo-ligase activity(GO:0004641) phosphoribosylglycinamide formyltransferase activity(GO:0004644)
0.0 0.1 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific)(GO:0046970)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.1 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.2 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 0.1 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0008746 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.2 GO:0016015 morphogen activity(GO:0016015)
0.0 0.9 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0019981 interleukin-6 receptor activity(GO:0004915) leukemia inhibitory factor receptor activity(GO:0004923) interleukin-6 binding(GO:0019981)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.3 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0046979 TAP2 binding(GO:0046979)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 1.0 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.7 PID IL23 PATHWAY IL23-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.0 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.4 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.8 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.7 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.1 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival