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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PROX1

Z-value: 0.78

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Transcription factors associated with PROX1

Gene Symbol Gene ID Gene Info
PROX1
ENSG00000117707.11 prospero homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
PROX1hg19_v2_chr1_+_214161272_2141613220.701.3e-01Click!

Activity profile of PROX1 motif

Sorted Z-values of PROX1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr8_+_142264664 0.47 ENST00000518520.1
RP11-10J21.3
Uncharacterized protein
chr1_+_179335101 0.45 ENST00000508285.1
ENST00000511889.1
AXDND1
axonemal dynein light chain domain containing 1
chr3_-_122283424 0.44 ENST00000477522.2
ENST00000360356.2
PARP9
poly (ADP-ribose) polymerase family, member 9
chr21_+_35736302 0.38 ENST00000290310.3
KCNE2
potassium voltage-gated channel, Isk-related family, member 2
chr3_+_190105909 0.38 ENST00000456423.1
CLDN16
claudin 16
chr6_-_107235331 0.37 ENST00000433965.1
ENST00000430094.1
RP1-60O19.1
RP1-60O19.1
chr16_+_28857957 0.36 ENST00000567536.1
SH2B1
SH2B adaptor protein 1
chr2_-_163175133 0.36 ENST00000421365.2
ENST00000263642.2
IFIH1
interferon induced with helicase C domain 1
chr1_-_152539248 0.32 ENST00000368789.1
LCE3E
late cornified envelope 3E
chr3_+_122283175 0.30 ENST00000383661.3
DTX3L
deltex 3-like (Drosophila)
chr18_-_21562500 0.25 ENST00000582300.2
RP11-403A21.1
RP11-403A21.1
chr17_+_77018896 0.25 ENST00000578229.1
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr21_-_16125773 0.25 ENST00000454128.2
AF127936.3
AF127936.3
chr6_-_8102279 0.25 ENST00000488226.2
EEF1E1
eukaryotic translation elongation factor 1 epsilon 1
chr7_-_143582450 0.24 ENST00000485416.1
FAM115A
family with sequence similarity 115, member A
chr1_+_154966058 0.22 ENST00000392487.1
LENEP
lens epithelial protein
chr10_-_75385711 0.22 ENST00000433394.1
USP54
ubiquitin specific peptidase 54
chr19_-_45909585 0.21 ENST00000593226.1
ENST00000418234.2
PPP1R13L
protein phosphatase 1, regulatory subunit 13 like
chr10_-_94301107 0.20 ENST00000436178.1
IDE
insulin-degrading enzyme
chr15_-_76304731 0.20 ENST00000394907.3
NRG4
neuregulin 4
chr1_+_70876891 0.20 ENST00000411986.2
CTH
cystathionase (cystathionine gamma-lyase)
chr4_-_48683188 0.19 ENST00000505759.1
FRYL
FRY-like
chr4_-_170947565 0.18 ENST00000506764.1
MFAP3L
microfibrillar-associated protein 3-like
chr1_+_26759295 0.18 ENST00000430232.1
DHDDS
dehydrodolichyl diphosphate synthase
chr1_+_70876926 0.18 ENST00000370938.3
ENST00000346806.2
CTH
cystathionase (cystathionine gamma-lyase)
chr1_+_82266053 0.18 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
LPHN2
latrophilin 2
chr10_+_30723045 0.17 ENST00000542547.1
ENST00000415139.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr10_+_134258649 0.17 ENST00000392630.3
ENST00000321248.2
C10orf91
chromosome 10 open reading frame 91
chr3_-_96337000 0.17 ENST00000600213.2
MTRNR2L12
MT-RNR2-like 12 (pseudogene)
chr1_-_44497118 0.16 ENST00000537678.1
ENST00000466926.1
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr2_-_107084826 0.16 ENST00000304514.7
ENST00000409886.3
RGPD3
RANBP2-like and GRIP domain containing 3
chr10_+_51549498 0.15 ENST00000358559.2
ENST00000298239.6
MSMB
microseminoprotein, beta-
chr7_-_91509986 0.15 ENST00000456229.1
ENST00000442961.1
ENST00000406735.2
ENST00000419292.1
ENST00000351870.3
MTERF
mitochondrial transcription termination factor
chr10_-_52008313 0.15 ENST00000329428.6
ENST00000395526.4
ENST00000447815.1
ASAH2
N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
chr4_+_164265035 0.15 ENST00000338566.3
NPY5R
neuropeptide Y receptor Y5
chr12_-_51418549 0.14 ENST00000548150.1
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
chr2_-_122262593 0.14 ENST00000418989.1
CLASP1
cytoplasmic linker associated protein 1
chr13_+_49822041 0.14 ENST00000538056.1
ENST00000251108.6
ENST00000444959.1
ENST00000429346.1
CDADC1
cytidine and dCMP deaminase domain containing 1
chr17_+_42081914 0.13 ENST00000293404.3
ENST00000589767.1
NAGS
N-acetylglutamate synthase
chr14_-_35183755 0.13 ENST00000555765.1
CFL2
cofilin 2 (muscle)
chr17_-_38074859 0.13 ENST00000520542.1
ENST00000418519.1
ENST00000394179.1
GSDMB
gasdermin B
chr9_+_133986782 0.13 ENST00000372301.2
AIF1L
allograft inflammatory factor 1-like
chr14_+_37641012 0.13 ENST00000556667.1
SLC25A21-AS1
SLC25A21 antisense RNA 1
chr11_-_4719072 0.13 ENST00000396950.3
ENST00000532598.1
OR51E2
olfactory receptor, family 51, subfamily E, member 2
chr2_-_225434538 0.13 ENST00000409096.1
CUL3
cullin 3
chrX_-_152486108 0.13 ENST00000356661.5
MAGEA1
melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
chr1_-_109399682 0.12 ENST00000369995.3
ENST00000370001.3
AKNAD1
AKNA domain containing 1
chr10_+_54074033 0.12 ENST00000373970.3
DKK1
dickkopf WNT signaling pathway inhibitor 1
chr14_-_23426231 0.12 ENST00000556915.1
HAUS4
HAUS augmin-like complex, subunit 4
chr12_+_10331605 0.12 ENST00000298530.3
TMEM52B
transmembrane protein 52B
chr22_-_45559540 0.12 ENST00000432502.1
CTA-217C2.1
CTA-217C2.1
chr1_-_109203685 0.11 ENST00000402983.1
ENST00000420055.1
HENMT1
HEN1 methyltransferase homolog 1 (Arabidopsis)
chr11_+_57308979 0.11 ENST00000457912.1
SMTNL1
smoothelin-like 1
chr18_+_2571510 0.11 ENST00000261597.4
ENST00000575515.1
NDC80
NDC80 kinetochore complex component
chr14_-_50559361 0.11 ENST00000305273.1
C14orf183
chromosome 14 open reading frame 183
chr1_-_154178803 0.11 ENST00000368525.3
C1orf189
chromosome 1 open reading frame 189
chr4_+_4861385 0.11 ENST00000382723.4
MSX1
msh homeobox 1
chr6_-_86303833 0.11 ENST00000505648.1
SNX14
sorting nexin 14
chr1_-_23342340 0.11 ENST00000566855.1
C1orf234
chromosome 1 open reading frame 234
chr22_-_45559642 0.10 ENST00000426282.2
CTA-217C2.1
CTA-217C2.1
chr5_-_127418573 0.10 ENST00000508353.1
ENST00000508878.1
ENST00000501652.1
ENST00000514409.1
CTC-228N24.3
CTC-228N24.3
chr19_-_5293243 0.10 ENST00000591760.1
PTPRS
protein tyrosine phosphatase, receptor type, S
chr10_+_112327425 0.10 ENST00000361804.4
SMC3
structural maintenance of chromosomes 3
chr8_+_110552831 0.10 ENST00000530629.1
EBAG9
estrogen receptor binding site associated, antigen, 9
chr10_+_30722866 0.10 ENST00000263056.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr19_+_45754505 0.10 ENST00000262891.4
ENST00000300843.4
MARK4
MAP/microtubule affinity-regulating kinase 4
chr21_-_16126181 0.10 ENST00000455253.2
AF127936.3
AF127936.3
chr3_-_33138592 0.10 ENST00000415454.1
GLB1
galactosidase, beta 1
chr16_+_22518495 0.10 ENST00000541154.1
NPIPB5
nuclear pore complex interacting protein family, member B5
chr19_-_9546227 0.10 ENST00000361451.2
ENST00000361151.1
ZNF266
zinc finger protein 266
chr12_-_46766577 0.10 ENST00000256689.5
SLC38A2
solute carrier family 38, member 2
chr19_+_53073526 0.10 ENST00000596514.1
ENST00000391785.3
ENST00000301093.2
ZNF701
zinc finger protein 701
chr7_+_64254793 0.10 ENST00000494380.1
ENST00000440155.2
ENST00000440598.1
ENST00000437743.1
ZNF138
zinc finger protein 138
chr3_-_130745403 0.10 ENST00000504725.1
ENST00000509060.1
ASTE1
asteroid homolog 1 (Drosophila)
chr16_+_28985542 0.10 ENST00000567771.1
ENST00000568388.1
SPNS1
spinster homolog 1 (Drosophila)
chr17_-_80009209 0.09 ENST00000429557.3
ENST00000578356.1
RFNG
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr6_-_159420780 0.09 ENST00000449822.1
RSPH3
radial spoke 3 homolog (Chlamydomonas)
chr16_+_58059470 0.09 ENST00000219271.3
MMP15
matrix metallopeptidase 15 (membrane-inserted)
chr3_-_25915189 0.09 ENST00000451284.1
LINC00692
long intergenic non-protein coding RNA 692
chr7_+_92158083 0.09 ENST00000265732.5
ENST00000481551.1
ENST00000496410.1
RBM48
RNA binding motif protein 48
chr2_+_232826394 0.09 ENST00000409401.3
ENST00000441279.1
DIS3L2
DIS3 mitotic control homolog (S. cerevisiae)-like 2
chr19_-_19754404 0.09 ENST00000587205.1
ENST00000445806.2
ENST00000203556.4
GMIP
GEM interacting protein
chr6_+_126102292 0.09 ENST00000368357.3
NCOA7
nuclear receptor coactivator 7
chr11_+_73359936 0.09 ENST00000542389.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr13_+_113699029 0.09 ENST00000423251.1
MCF2L
MCF.2 cell line derived transforming sequence-like
chr1_+_246729724 0.09 ENST00000366513.4
ENST00000366512.3
CNST
consortin, connexin sorting protein
chr10_+_32735030 0.09 ENST00000277657.6
ENST00000362006.5
CCDC7
coiled-coil domain containing 7
chr4_-_38666430 0.08 ENST00000436901.1
AC021860.1
Uncharacterized protein
chr7_+_156433363 0.08 ENST00000439609.1
RNF32
ring finger protein 32
chr21_-_34863693 0.08 ENST00000314399.3
DNAJC28
DnaJ (Hsp40) homolog, subfamily C, member 28
chr6_+_111580508 0.08 ENST00000368847.4
KIAA1919
KIAA1919
chr11_+_6518503 0.08 ENST00000496802.1
ENST00000254579.6
ENST00000354685.3
DNHD1
dynein heavy chain domain 1
chr1_-_109203648 0.08 ENST00000370031.1
HENMT1
HEN1 methyltransferase homolog 1 (Arabidopsis)
chr6_-_28226984 0.08 ENST00000423974.2
ZKSCAN4
zinc finger with KRAB and SCAN domains 4
chr7_+_64254766 0.08 ENST00000307355.7
ENST00000359735.3
ZNF138
zinc finger protein 138
chr7_-_91509972 0.08 ENST00000425936.1
MTERF
mitochondrial transcription termination factor
chr2_+_163175394 0.08 ENST00000446271.1
ENST00000429691.2
GCA
grancalcin, EF-hand calcium binding protein
chr9_+_125132803 0.07 ENST00000540753.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr11_-_111749878 0.07 ENST00000260257.4
FDXACB1
ferredoxin-fold anticodon binding domain containing 1
chr3_-_19975665 0.07 ENST00000295824.9
ENST00000389256.4
EFHB
EF-hand domain family, member B
chrY_+_22918021 0.07 ENST00000288666.5
RPS4Y2
ribosomal protein S4, Y-linked 2
chr19_-_46234119 0.07 ENST00000317683.3
FBXO46
F-box protein 46
chr13_+_27131887 0.07 ENST00000335327.5
WASF3
WAS protein family, member 3
chr17_+_80009330 0.07 ENST00000580716.1
ENST00000583961.1
GPS1
G protein pathway suppressor 1
chr4_+_26862313 0.07 ENST00000467087.1
ENST00000382009.3
ENST00000237364.5
STIM2
stromal interaction molecule 2
chr4_-_170947522 0.07 ENST00000361618.3
MFAP3L
microfibrillar-associated protein 3-like
chr9_+_34990219 0.07 ENST00000541010.1
ENST00000454002.2
ENST00000545841.1
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr6_-_42690312 0.07 ENST00000230381.5
PRPH2
peripherin 2 (retinal degeneration, slow)
chr6_+_144665237 0.07 ENST00000421035.2
UTRN
utrophin
chr8_-_19615382 0.07 ENST00000544602.1
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr2_+_108443388 0.07 ENST00000354986.4
ENST00000408999.3
RGPD4
RANBP2-like and GRIP domain containing 4
chr1_+_6640046 0.07 ENST00000319084.5
ENST00000435905.1
ZBTB48
zinc finger and BTB domain containing 48
chr2_-_136288113 0.07 ENST00000401392.1
ZRANB3
zinc finger, RAN-binding domain containing 3
chr3_+_138067314 0.07 ENST00000423968.2
MRAS
muscle RAS oncogene homolog
chr19_+_6361754 0.07 ENST00000597326.1
CLPP
caseinolytic mitochondrial matrix peptidase proteolytic subunit
chr11_+_93394805 0.07 ENST00000325212.6
ENST00000411936.1
ENST00000344196.4
KIAA1731
KIAA1731
chr3_-_130745571 0.07 ENST00000514044.1
ENST00000264992.3
ASTE1
asteroid homolog 1 (Drosophila)
chr16_-_21442874 0.07 ENST00000534903.1
NPIPB3
nuclear pore complex interacting protein family, member B3
chr2_-_65659762 0.07 ENST00000440972.1
SPRED2
sprouty-related, EVH1 domain containing 2
chr4_-_128887069 0.06 ENST00000541133.1
ENST00000296468.3
ENST00000513559.1
MFSD8
major facilitator superfamily domain containing 8
chr14_-_54425475 0.06 ENST00000559642.1
BMP4
bone morphogenetic protein 4
chr10_-_121296045 0.06 ENST00000392865.1
RGS10
regulator of G-protein signaling 10
chr8_+_145064233 0.06 ENST00000529301.1
ENST00000395068.4
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr9_-_130497565 0.06 ENST00000336067.6
ENST00000373281.5
ENST00000373284.5
ENST00000458505.3
TOR2A
torsin family 2, member A
chr7_+_18126557 0.06 ENST00000417496.2
HDAC9
histone deacetylase 9
chr12_+_52668394 0.06 ENST00000423955.2
KRT86
keratin 86
chr11_+_73360024 0.06 ENST00000540431.1
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr9_+_95858485 0.06 ENST00000375464.2
C9orf89
chromosome 9 open reading frame 89
chr11_+_117947724 0.06 ENST00000534111.1
TMPRSS4
transmembrane protease, serine 4
chr8_+_145064215 0.06 ENST00000313269.5
GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr7_+_100210133 0.06 ENST00000393950.2
ENST00000424091.2
MOSPD3
motile sperm domain containing 3
chr10_+_16478942 0.05 ENST00000535784.2
ENST00000423462.2
ENST00000378000.1
PTER
phosphotriesterase related
chr3_+_126113734 0.05 ENST00000352312.1
ENST00000393425.1
CCDC37
coiled-coil domain containing 37
chr8_+_110552046 0.05 ENST00000529931.1
EBAG9
estrogen receptor binding site associated, antigen, 9
chr2_-_175202151 0.05 ENST00000595354.1
AC018470.1
Uncharacterized protein FLJ46347
chr5_-_22853429 0.05 ENST00000504376.2
CDH12
cadherin 12, type 2 (N-cadherin 2)
chr5_+_154320623 0.05 ENST00000523037.1
ENST00000265229.8
ENST00000439747.3
ENST00000522038.1
MRPL22
mitochondrial ribosomal protein L22
chr9_-_127533519 0.05 ENST00000487099.2
ENST00000344523.4
ENST00000373584.3
NR6A1
nuclear receptor subfamily 6, group A, member 1
chr5_-_72861175 0.05 ENST00000504641.1
ANKRA2
ankyrin repeat, family A (RFXANK-like), 2
chr1_+_154909803 0.05 ENST00000604546.1
RP11-307C12.13
RP11-307C12.13
chr19_+_1354930 0.05 ENST00000591337.1
MUM1
melanoma associated antigen (mutated) 1
chr1_-_111061797 0.05 ENST00000369771.2
KCNA10
potassium voltage-gated channel, shaker-related subfamily, member 10
chr3_+_12525931 0.05 ENST00000446004.1
ENST00000314571.7
ENST00000454502.2
ENST00000383797.5
ENST00000402228.3
ENST00000284995.6
ENST00000444864.1
TSEN2
TSEN2 tRNA splicing endonuclease subunit
chr15_+_85523671 0.05 ENST00000310298.4
ENST00000557957.1
PDE8A
phosphodiesterase 8A
chr4_-_69215699 0.05 ENST00000510746.1
ENST00000344157.4
ENST00000355665.3
YTHDC1
YTH domain containing 1
chr15_+_38746307 0.05 ENST00000397609.2
ENST00000491535.1
FAM98B
family with sequence similarity 98, member B
chr11_+_60609537 0.05 ENST00000227520.5
CCDC86
coiled-coil domain containing 86
chr16_+_23194033 0.05 ENST00000300061.2
SCNN1G
sodium channel, non-voltage-gated 1, gamma subunit
chr4_+_26862431 0.05 ENST00000465503.1
STIM2
stromal interaction molecule 2
chr14_+_78266408 0.05 ENST00000238561.5
ADCK1
aarF domain containing kinase 1
chr1_+_161719552 0.05 ENST00000367943.4
DUSP12
dual specificity phosphatase 12
chr11_-_73882029 0.05 ENST00000539061.1
C2CD3
C2 calcium-dependent domain containing 3
chr7_+_100209979 0.05 ENST00000493970.1
ENST00000379527.2
MOSPD3
motile sperm domain containing 3
chr7_-_156433195 0.05 ENST00000333319.6
C7orf13
chromosome 7 open reading frame 13
chr4_+_26862400 0.04 ENST00000467011.1
ENST00000412829.2
STIM2
stromal interaction molecule 2
chr7_-_99716952 0.04 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr9_-_86571628 0.04 ENST00000376344.3
C9orf64
chromosome 9 open reading frame 64
chr1_+_35544968 0.04 ENST00000359858.4
ENST00000373330.1
ZMYM1
zinc finger, MYM-type 1
chr6_-_137540477 0.04 ENST00000367735.2
ENST00000367739.4
ENST00000458076.1
ENST00000414770.1
IFNGR1
interferon gamma receptor 1
chr16_+_31724552 0.04 ENST00000539915.1
ENST00000316491.9
ENST00000399681.3
ENST00000398696.3
ENST00000534369.1
ZNF720
zinc finger protein 720
chr2_+_139259324 0.04 ENST00000280098.4
SPOPL
speckle-type POZ protein-like
chrX_+_150565038 0.04 ENST00000370361.1
VMA21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr5_-_156569850 0.04 ENST00000524219.1
HAVCR2
hepatitis A virus cellular receptor 2
chr3_+_138066539 0.04 ENST00000289104.4
MRAS
muscle RAS oncogene homolog
chr15_-_74726283 0.04 ENST00000543145.2
SEMA7A
semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
chr16_-_4524543 0.04 ENST00000573571.1
ENST00000404295.3
ENST00000574425.1
NMRAL1
NmrA-like family domain containing 1
chr4_+_128886584 0.04 ENST00000513371.1
C4orf29
chromosome 4 open reading frame 29
chr14_-_105708942 0.04 ENST00000549655.1
BRF1
BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
chr9_-_127533582 0.04 ENST00000416460.2
NR6A1
nuclear receptor subfamily 6, group A, member 1
chr22_+_45559722 0.04 ENST00000347635.4
ENST00000407019.2
ENST00000424634.1
ENST00000417702.1
ENST00000425733.2
ENST00000430547.1
NUP50
nucleoporin 50kDa
chr20_+_57209828 0.04 ENST00000598340.1
MGC4294
HCG1785561; MGC4294 protein; Uncharacterized protein
chr5_-_53115506 0.04 ENST00000511953.1
ENST00000504552.1
CTD-2081C10.1
CTD-2081C10.1
chr20_-_7921090 0.04 ENST00000378789.3
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr13_+_27131798 0.04 ENST00000361042.4
WASF3
WAS protein family, member 3
chr5_+_64859066 0.04 ENST00000261308.5
ENST00000535264.1
ENST00000538977.1
PPWD1
peptidylprolyl isomerase domain and WD repeat containing 1
chr6_-_74104856 0.03 ENST00000441145.1
OOEP
oocyte expressed protein
chr19_+_58281014 0.03 ENST00000391702.3
ENST00000598885.1
ENST00000598183.1
ENST00000396154.2
ENST00000599802.1
ENST00000396150.4
ZNF586
zinc finger protein 586
chr1_-_204380919 0.03 ENST00000367188.4
PPP1R15B
protein phosphatase 1, regulatory subunit 15B
chr10_+_45869652 0.03 ENST00000542434.1
ENST00000374391.2
ALOX5
arachidonate 5-lipoxygenase
chr10_+_104474353 0.03 ENST00000602647.1
ENST00000602439.1
ENST00000602764.1
SFXN2
sideroflexin 2
chr9_+_125133467 0.03 ENST00000426608.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr2_+_101869262 0.03 ENST00000289382.3
CNOT11
CCR4-NOT transcription complex, subunit 11
chr11_+_73882144 0.03 ENST00000328257.8
PPME1
protein phosphatase methylesterase 1
chr22_-_29075853 0.03 ENST00000397906.2
TTC28
tetratricopeptide repeat domain 28
chr7_-_102158157 0.03 ENST00000541662.1
ENST00000306682.6
ENST00000465829.1
RASA4B
RAS p21 protein activator 4B
chr1_-_151431674 0.03 ENST00000531094.1
POGZ
pogo transposable element with ZNF domain
chr12_-_122658746 0.03 ENST00000377035.1
IL31
interleukin 31
chr19_-_4400415 0.03 ENST00000598564.1
ENST00000417295.2
ENST00000269886.3
SH3GL1
SH3-domain GRB2-like 1
chr3_-_196014520 0.03 ENST00000441879.1
ENST00000292823.2
ENST00000411591.1
ENST00000431016.1
ENST00000443555.1
PCYT1A
phosphate cytidylyltransferase 1, choline, alpha
chr3_-_100565249 0.03 ENST00000495591.1
ENST00000383691.4
ENST00000466947.1
ABI3BP
ABI family, member 3 (NESH) binding protein
chr15_+_81489213 0.03 ENST00000559383.1
ENST00000394660.2
IL16
interleukin 16
chr12_-_52946923 0.03 ENST00000267119.5
KRT71
keratin 71
chr8_-_146176199 0.03 ENST00000532351.1
ENST00000276816.4
ENST00000394909.2
ZNF16
zinc finger protein 16
chr8_-_37824442 0.03 ENST00000345060.3
ADRB3
adrenoceptor beta 3
chr3_+_137906353 0.03 ENST00000461822.1
ENST00000485396.1
ENST00000471453.1
ENST00000470821.1
ENST00000471709.1
ENST00000538260.1
ENST00000393058.3
ENST00000463485.1
ARMC8
armadillo repeat containing 8
chr4_-_159592996 0.03 ENST00000508457.1
C4orf46
chromosome 4 open reading frame 46
chr19_+_917287 0.03 ENST00000592648.1
ENST00000234371.5
KISS1R
KISS1 receptor
chr1_+_165864821 0.03 ENST00000470820.1
UCK2
uridine-cytidine kinase 2
chr16_+_50300427 0.03 ENST00000394697.2
ENST00000566433.2
ENST00000538642.1
ADCY7
adenylate cyclase 7
chr16_+_28858004 0.03 ENST00000322610.8
SH2B1
SH2B adaptor protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of PROX1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.1 0.4 GO:0034344 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.1 0.4 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979) regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.1 0.2 GO:1901143 insulin catabolic process(GO:1901143)
0.0 0.2 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.0 0.1 GO:0100012 negative regulation of mesodermal cell fate specification(GO:0042662) regulation of heart induction(GO:0090381) regulation of heart induction by canonical Wnt signaling pathway(GO:0100012)
0.0 0.4 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 0.1 GO:0090427 activation of meiosis(GO:0090427)
0.0 0.1 GO:0034164 negative regulation of toll-like receptor 9 signaling pathway(GO:0034164)
0.0 0.1 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.0 0.3 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.1 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.0 0.1 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:0015692 lead ion transport(GO:0015692)
0.0 0.0 GO:0002835 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838) negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859)
0.0 0.3 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.1 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 0.1 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.4 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.2 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.1 GO:0019046 release from viral latency(GO:0019046)
0.0 0.0 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.0 0.1 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.1 GO:0071893 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 0.0 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.0 GO:0002025 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.1 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.1 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.1 GO:0009368 endopeptidase Clp complex(GO:0009368)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.0 GO:0000126 transcription factor TFIIIB complex(GO:0000126)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.2 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.1 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 0.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.4 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.1 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.1 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.4 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.4 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.0 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 0.2 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.0 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.0 0.0 GO:0001026 TFIIIB-type transcription factor activity(GO:0001026)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.4 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling