Project
A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
Navigation
Downloads
Results for PPARA
Z-value: 0.84
Motif logo
Transcription factors associated with PPARA
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| PPARA | hg19_v2_chr22_+_46546494_46546525 | -0.67 | 1.5e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr14_+_21492331 Show fit | 0.85 |
ENST00000533984.1
ENST00000532213.2 |
AL161668.5 |
|
| chr2_+_228678550 Show fit | 0.84 |
ENST00000409189.3
ENST00000358813.4 |
chemokine (C-C motif) ligand 20 |
|
| chr4_-_155533787 Show fit | 0.77 |
ENST00000407946.1
ENST00000405164.1 ENST00000336098.3 ENST00000393846.2 ENST00000404648.3 ENST00000443553.1 |
fibrinogen gamma chain |
|
| chr1_-_156675564 Show fit | 0.67 |
ENST00000368220.1
|
cellular retinoic acid binding protein 2 |
|
| chr19_+_10197463 Show fit | 0.65 |
ENST00000590378.1
ENST00000397881.3 |
chromosome 19 open reading frame 66 |
|
| chr11_-_790060 Show fit | 0.65 |
ENST00000330106.4
|
cell cycle exit and neuronal differentiation 1 |
|
| chr17_-_4889508 Show fit | 0.53 |
ENST00000574606.2
|
calmodulin binding transcription activator 2 |
|
| chr1_+_45140400 Show fit | 0.50 |
ENST00000453711.1
|
chromosome 1 open reading frame 228 |
|
| chr13_+_103046954 Show fit | 0.50 |
ENST00000606448.1
|
FGF14 antisense RNA 2 |
|
| chr17_-_38821373 Show fit | 0.49 |
ENST00000394052.3
|
keratin 222 |
Network of associatons between targets according to the STRING database.
First level regulatory network of PPARA
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 1.0 | GO:2000567 | memory T cell activation(GO:0035709) regulation of memory T cell activation(GO:2000567) positive regulation of memory T cell activation(GO:2000568) |
| 0.3 | 0.8 | GO:0045362 | interleukin-1 biosynthetic process(GO:0042222) regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) |
| 0.0 | 0.8 | GO:0034116 | positive regulation of heterotypic cell-cell adhesion(GO:0034116) |
| 0.1 | 0.7 | GO:0030421 | defecation(GO:0030421) |
| 0.0 | 0.7 | GO:0048672 | positive regulation of collateral sprouting(GO:0048672) |
| 0.2 | 0.6 | GO:1990926 | short-term synaptic potentiation(GO:1990926) |
| 0.1 | 0.6 | GO:0021699 | cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699) |
| 0.0 | 0.6 | GO:0035020 | regulation of Rac protein signal transduction(GO:0035020) |
| 0.2 | 0.5 | GO:0060629 | regulation of homologous chromosome segregation(GO:0060629) |
| 0.1 | 0.5 | GO:2000158 | positive regulation of ubiquitin-specific protease activity(GO:2000158) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.1 | 0.8 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.1 | 0.7 | GO:0031415 | NatA complex(GO:0031415) |
| 0.1 | 0.6 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) |
| 0.0 | 0.6 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
| 0.0 | 0.6 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.0 | 0.6 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.1 | 0.5 | GO:0042721 | mitochondrial inner membrane protein insertion complex(GO:0042721) |
| 0.0 | 0.5 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 0.0 | 0.5 | GO:0000795 | synaptonemal complex(GO:0000795) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.0 | GO:0023030 | MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030) |
| 0.3 | 0.8 | GO:0031731 | CCR6 chemokine receptor binding(GO:0031731) |
| 0.0 | 0.8 | GO:0019841 | retinol binding(GO:0019841) |
| 0.0 | 0.7 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.0 | 0.6 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.0 | 0.6 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.1 | 0.5 | GO:0030172 | troponin C binding(GO:0030172) |
| 0.1 | 0.5 | GO:0035800 | deubiquitinase activator activity(GO:0035800) |
| 0.0 | 0.5 | GO:0008556 | sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556) |
| 0.0 | 0.5 | GO:0019992 | diacylglycerol binding(GO:0019992) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.6 | PID INTEGRIN1 PATHWAY | Beta1 integrin cell surface interactions |
| 0.0 | 0.8 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 0.6 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.8 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 0.7 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 0.0 | 0.6 | REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
| 0.0 | 0.6 | REACTOME INTRINSIC PATHWAY | Genes involved in Intrinsic Pathway |
| 0.0 | 0.6 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.0 | 0.5 | REACTOME HYALURONAN UPTAKE AND DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
| 0.0 | 0.5 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 0.0 | 0.5 | REACTOME SEMA3A PAK DEPENDENT AXON REPULSION | Genes involved in Sema3A PAK dependent Axon repulsion |
| 0.0 | 0.4 | REACTOME STEROID HORMONES | Genes involved in Steroid hormones |
| 0.0 | 0.3 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |