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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for POU5F1_POU2F3

Z-value: 1.43

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Transcription factors associated with POU5F1_POU2F3

Gene Symbol Gene ID Gene Info
ENSG00000204531.11 POU class 5 homeobox 1
ENSG00000137709.5 POU class 2 homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU5F1hg19_v2_chr6_-_31138439_311384750.394.4e-01Click!
POU2F3hg19_v2_chr11_+_120110863_1201109080.167.6e-01Click!

Activity profile of POU5F1_POU2F3 motif

Sorted Z-values of POU5F1_POU2F3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_35658007 2.35 ENST00000602361.1
RNA component of mitochondrial RNA processing endoribonuclease
chr11_+_313503 1.32 ENST00000528780.1
ENST00000328221.5
interferon induced transmembrane protein 1
chr12_+_113344811 1.30 ENST00000551241.1
ENST00000553185.1
ENST00000550689.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr12_+_113344582 1.29 ENST00000202917.5
ENST00000445409.2
ENST00000452357.2
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr12_+_113344755 1.27 ENST00000550883.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr12_-_7245125 1.21 ENST00000542285.1
ENST00000540610.1
complement component 1, r subcomponent
chr1_-_27701307 1.19 ENST00000270879.4
ENST00000354982.2
ficolin (collagen/fibrinogen domain containing) 3
chr12_-_7245152 1.05 ENST00000542220.2
complement component 1, r subcomponent
chr6_+_27114861 1.02 ENST00000377459.1
histone cluster 1, H2ah
chr12_-_7245080 1.01 ENST00000541042.1
ENST00000540242.1
complement component 1, r subcomponent
chr6_-_26043885 1.01 ENST00000357905.2
histone cluster 1, H2bb
chr12_+_113354341 0.98 ENST00000553152.1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr12_-_7245018 0.92 ENST00000543835.1
ENST00000535233.2
complement component 1, r subcomponent
chr9_-_32526299 0.88 ENST00000379882.1
ENST00000379883.2
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr3_-_122283079 0.87 ENST00000471785.1
ENST00000466126.1
poly (ADP-ribose) polymerase family, member 9
chr17_+_38171681 0.84 ENST00000225474.2
ENST00000331769.2
ENST00000394148.3
ENST00000577675.1
colony stimulating factor 3 (granulocyte)
chr3_-_122283100 0.83 ENST00000492382.1
ENST00000462315.1
poly (ADP-ribose) polymerase family, member 9
chr2_-_113594279 0.81 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
interleukin 1, beta
chr3_+_50192457 0.76 ENST00000414301.1
ENST00000450338.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr2_+_162101247 0.74 ENST00000439050.1
ENST00000436506.1
AC009299.3
chr1_-_149859466 0.71 ENST00000331128.3
histone cluster 2, H2ab
chr2_+_114163945 0.71 ENST00000453673.3
immunoglobulin kappa variable 1/OR2-108 (non-functional)
chr18_+_77867177 0.69 ENST00000560752.1
ADNP homeobox 2
chr11_-_31832685 0.68 ENST00000438681.1
paired box 6
chr9_+_108424738 0.67 ENST00000334077.3
T-cell acute lymphocytic leukemia 2
chr12_-_56359802 0.66 ENST00000548803.1
ENST00000449260.2
ENST00000550447.1
ENST00000547137.1
ENST00000546543.1
ENST00000550464.1
premelanosome protein
chr17_+_19091325 0.65 ENST00000584923.1
small nucleolar RNA, C/D box 3A
chr19_-_17516449 0.64 ENST00000252593.6
bone marrow stromal cell antigen 2
chr22_+_43011247 0.60 ENST00000602478.1
RNA, U12 small nuclear
chr1_-_149858227 0.59 ENST00000369155.2
histone cluster 2, H2be
chr22_-_24096630 0.58 ENST00000248948.3
pre-B lymphocyte 3
chr3_-_122283424 0.57 ENST00000477522.2
ENST00000360356.2
poly (ADP-ribose) polymerase family, member 9
chr6_-_13621126 0.53 ENST00000600057.1
Uncharacterized protein
chr6_+_131571535 0.53 ENST00000474850.2
A kinase (PRKA) anchor protein 7
chr3_+_122283064 0.51 ENST00000296161.4
deltex 3-like (Drosophila)
chr1_+_79115503 0.50 ENST00000370747.4
ENST00000438486.1
ENST00000545124.1
interferon-induced protein 44
chr6_+_26183958 0.49 ENST00000356530.3
histone cluster 1, H2be
chr6_+_31895467 0.48 ENST00000556679.1
ENST00000456570.1
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr16_+_82660635 0.48 ENST00000567445.1
ENST00000446376.2
cadherin 13
chr17_-_38821373 0.47 ENST00000394052.3
keratin 222
chr12_+_132312931 0.45 ENST00000360564.1
ENST00000545671.1
ENST00000545790.1
matrix metallopeptidase 17 (membrane-inserted)
chr6_-_11779403 0.44 ENST00000414691.3
androgen-dependent TFPI-regulating protein
chr2_-_192016276 0.44 ENST00000413064.1
signal transducer and activator of transcription 4
chr1_+_68150744 0.44 ENST00000370986.4
ENST00000370985.3
growth arrest and DNA-damage-inducible, alpha
chr9_-_117160738 0.44 ENST00000448674.1
RP11-9M16.2
chr19_+_11466167 0.44 ENST00000591608.1
Lipid phosphate phosphatase-related protein type 2
chrX_-_48776292 0.43 ENST00000376509.4
pim-2 oncogene
chr17_-_19015945 0.42 ENST00000573866.2
small nucleolar RNA, C/D box 3D
chr7_+_142982023 0.42 ENST00000359333.3
ENST00000409244.1
ENST00000409541.1
ENST00000410004.1
transmembrane protein 139
chr6_+_27782788 0.42 ENST00000359465.4
histone cluster 1, H2bm
chr17_-_46894576 0.41 ENST00000393382.3
tubulin tyrosine ligase-like family, member 6
chr12_+_9102632 0.39 ENST00000539240.1
killer cell lectin-like receptor subfamily G, member 1
chr12_-_74796291 0.39 ENST00000551726.1
RP11-81H3.2
chr7_-_83824449 0.38 ENST00000420047.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr16_-_90096309 0.37 ENST00000408886.2
chromosome 16 open reading frame 3
chr11_-_62609281 0.37 ENST00000525239.1
ENST00000538098.2
WD repeat domain 74
chr17_-_39023462 0.37 ENST00000251643.4
keratin 12
chr6_+_31895480 0.37 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
complement component 2
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr5_-_141030943 0.37 ENST00000522783.1
ENST00000519800.1
ENST00000435817.2
FCH and double SH3 domains 1
chr7_-_47520869 0.36 ENST00000415929.1
tensin 3
chr11_+_34642656 0.36 ENST00000257831.3
ENST00000450654.2
ets homologous factor
chr6_+_26217159 0.36 ENST00000303910.2
histone cluster 1, H2ae
chr12_-_11175219 0.36 ENST00000390673.2
taste receptor, type 2, member 19
chr13_+_76378357 0.35 ENST00000489941.2
ENST00000525373.1
LIM domain 7
chr11_-_94964210 0.35 ENST00000416495.2
ENST00000393234.1
sestrin 3
chr1_-_198906528 0.35 ENST00000432296.1
MIR181A1 host gene (non-protein coding)
chr6_-_26033796 0.35 ENST00000259791.2
histone cluster 1, H2ab
chr19_+_39903185 0.34 ENST00000409794.3
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr11_+_110225855 0.34 ENST00000526605.1
ENST00000526703.1
RP11-347E10.1
chr3_+_122283175 0.34 ENST00000383661.3
deltex 3-like (Drosophila)
chr3_+_50192833 0.34 ENST00000426511.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr19_+_11466062 0.33 ENST00000251473.5
ENST00000591329.1
ENST00000586380.1
Lipid phosphate phosphatase-related protein type 2
chr14_-_107035208 0.32 ENST00000390626.2
immunoglobulin heavy variable 5-51
chr3_+_50192499 0.32 ENST00000413852.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr3_+_50192537 0.32 ENST00000002829.3
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr14_+_71679350 0.31 ENST00000553621.1
RP6-91H8.1
chr2_+_242913327 0.31 ENST00000426962.1
AC093642.3
chr4_-_155533787 0.31 ENST00000407946.1
ENST00000405164.1
ENST00000336098.3
ENST00000393846.2
ENST00000404648.3
ENST00000443553.1
fibrinogen gamma chain
chr6_-_52668605 0.31 ENST00000334575.5
glutathione S-transferase alpha 1
chr10_+_91061712 0.31 ENST00000371826.3
interferon-induced protein with tetratricopeptide repeats 2
chr17_-_63557309 0.30 ENST00000580513.1
axin 2
chr4_-_144826682 0.30 ENST00000358615.4
ENST00000437468.2
glycophorin E (MNS blood group)
chr14_+_65007177 0.30 ENST00000247207.6
heat shock 70kDa protein 2
chr22_-_24096562 0.30 ENST00000398465.3
pre-B lymphocyte 3
chr9_-_37384431 0.30 ENST00000452923.1
RP11-397D12.4
chr7_-_3083573 0.30 ENST00000396946.4
caspase recruitment domain family, member 11
chr22_+_24577183 0.30 ENST00000358321.3
sushi domain containing 2
chr14_-_92413727 0.29 ENST00000267620.10
fibulin 5
chr10_-_37891859 0.29 ENST00000544824.1
MT-RNR2-like 7
chr1_-_108231101 0.29 ENST00000544443.1
ENST00000415432.2
vav 3 guanine nucleotide exchange factor
chr18_-_61311485 0.29 ENST00000436264.1
ENST00000356424.6
ENST00000341074.5
serpin peptidase inhibitor, clade B (ovalbumin), member 4
chr12_+_78359999 0.29 ENST00000550503.1
neuron navigator 3
chr1_+_218683438 0.29 ENST00000443836.1
chromosome 1 open reading frame 143
chr19_-_19281054 0.29 ENST00000424583.2
ENST00000410050.1
ENST00000409224.1
ENST00000409447.2
myocyte enhancer factor 2B
chr17_-_79620721 0.28 ENST00000571004.1
phosphodiesterase 6G, cGMP-specific, rod, gamma
chr19_-_23456996 0.28 ENST00000594653.1
RP11-15H20.7
chr9_-_84303269 0.28 ENST00000418319.1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr6_+_41010293 0.28 ENST00000373161.1
ENST00000373158.2
ENST00000470917.1
translocator protein 2
chr5_-_172198190 0.28 ENST00000239223.3
dual specificity phosphatase 1
chr21_-_33975547 0.27 ENST00000431599.1
chromosome 21 open reading frame 59
chr15_-_79576156 0.27 ENST00000560452.1
ENST00000560872.1
ENST00000560732.1
ENST00000559979.1
ENST00000560533.1
ENST00000559225.1
RP11-17L5.4
chr17_+_62461569 0.27 ENST00000603557.1
ENST00000605096.1
mast cell immunoglobulin-like receptor 1
chr15_+_65337708 0.27 ENST00000334287.2
solute carrier family 51, beta subunit
chr14_-_34420259 0.27 ENST00000250457.3
ENST00000547327.2
egl-9 family hypoxia-inducible factor 3
chr1_+_45140400 0.27 ENST00000453711.1
chromosome 1 open reading frame 228
chr12_-_67072714 0.27 ENST00000545666.1
ENST00000398016.3
ENST00000359742.4
ENST00000286445.7
ENST00000538211.1
glutamate receptor interacting protein 1
chr2_+_136343904 0.27 ENST00000436436.1
R3H domain containing 1
chr19_+_926000 0.26 ENST00000263620.3
AT rich interactive domain 3A (BRIGHT-like)
chr1_-_196577489 0.26 ENST00000609185.1
ENST00000451324.2
ENST00000367433.5
ENST00000367431.4
potassium channel, subfamily T, member 2
chr19_+_36602104 0.26 ENST00000585332.1
ENST00000262637.4
ovo-like zinc finger 3
chr4_-_157892055 0.26 ENST00000422544.2
platelet derived growth factor C
chr4_-_39034542 0.26 ENST00000344606.6
transmembrane protein 156
chr14_-_21270995 0.26 ENST00000555698.1
ENST00000397970.4
ENST00000340900.3
ribonuclease, RNase A family, 1 (pancreatic)
chr15_-_41522889 0.25 ENST00000458580.2
ENST00000314992.5
ENST00000558396.1
exonuclease 3'-5' domain containing 1
chr9_+_33750515 0.25 ENST00000361005.5
protease, serine, 3
chr16_-_69418553 0.25 ENST00000569542.2
telomeric repeat binding factor 2
chr17_-_73840614 0.25 ENST00000586108.1
unc-13 homolog D (C. elegans)
chr22_+_38035623 0.25 ENST00000336738.5
ENST00000442465.2
SH3-domain binding protein 1
chr3_+_52720187 0.25 ENST00000474423.1
guanine nucleotide binding protein-like 3 (nucleolar)
chr6_-_26235206 0.24 ENST00000244534.5
histone cluster 1, H1d
chr13_+_76378305 0.24 ENST00000526371.1
ENST00000526528.1
LIM domain 7
chr16_-_4323015 0.24 ENST00000204517.6
transcription factor AP-4 (activating enhancer binding protein 4)
chr17_+_57233087 0.23 ENST00000578777.1
ENST00000577457.1
ENST00000582995.1
proline rich 11
chr21_+_35107346 0.23 ENST00000456489.1
intersectin 1 (SH3 domain protein)
chr1_+_28206150 0.23 ENST00000456990.1
thymocyte selection associated family member 2
chr4_+_76481258 0.23 ENST00000311623.4
ENST00000435974.2
chromosome 4 open reading frame 26
chr15_-_80263506 0.23 ENST00000335661.6
BCL2-related protein A1
chr15_-_55657428 0.23 ENST00000568543.1
cell cycle progression 1
chr14_-_92413353 0.23 ENST00000556154.1
fibulin 5
chr8_-_117886612 0.22 ENST00000520992.1
RAD21 homolog (S. pombe)
chr16_+_55522536 0.22 ENST00000570283.1
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr18_-_60985914 0.22 ENST00000589955.1
B-cell CLL/lymphoma 2
chr17_+_38171614 0.22 ENST00000583218.1
ENST00000394149.3
colony stimulating factor 3 (granulocyte)
chr8_+_107593198 0.22 ENST00000517686.1
oxidation resistance 1
chr4_-_71532339 0.22 ENST00000254801.4
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr19_+_21203426 0.22 ENST00000261560.5
ENST00000599548.1
ENST00000594110.1
zinc finger protein 430
chr8_-_99955042 0.21 ENST00000519420.1
serine/threonine kinase 3
chr8_+_66619277 0.21 ENST00000521247.2
ENST00000527155.1
mitochondrial fission regulator 1
chr3_+_197464046 0.21 ENST00000428738.1
forty-two-three domain containing 1
chr5_-_39270725 0.21 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYN binding protein
chr17_+_14204389 0.21 ENST00000360954.2
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr1_-_152539248 0.21 ENST00000368789.1
late cornified envelope 3E
chr6_-_169582835 0.21 ENST00000564830.1
RP11-417E7.2
chr9_+_103204553 0.21 ENST00000502978.1
ENST00000334943.6
MSANTD3-TMEFF1 readthrough
transmembrane protein with EGF-like and two follistatin-like domains 1
chr7_-_73038822 0.21 ENST00000414749.2
ENST00000429400.2
ENST00000434326.1
MLX interacting protein-like
chr16_-_69418649 0.21 ENST00000566257.1
telomeric repeat binding factor 2
chr17_+_38219063 0.21 ENST00000584985.1
ENST00000264637.4
ENST00000450525.2
thyroid hormone receptor, alpha
chr11_-_31832862 0.20 ENST00000379115.4
paired box 6
chr10_-_3827371 0.20 ENST00000469435.1
Kruppel-like factor 6
chr4_-_54424366 0.20 ENST00000306888.2
ligand of numb-protein X 1, E3 ubiquitin protein ligase
chr5_+_49961727 0.20 ENST00000505697.2
ENST00000503750.2
ENST00000514342.2
poly (ADP-ribose) polymerase family, member 8
chr11_-_10822029 0.20 ENST00000528839.1
eukaryotic translation initiation factor 4 gamma, 2
chr19_+_12035878 0.20 ENST00000254321.5
ENST00000538752.1
ENST00000590798.1
zinc finger protein 700
zinc finger protein 763
Uncharacterized protein; Zinc finger protein 763
chr12_+_133707161 0.20 ENST00000538918.1
ENST00000540609.1
ENST00000248211.6
ENST00000543271.1
ENST00000536877.1
zinc finger protein 10
chr3_+_57882061 0.20 ENST00000461354.1
ENST00000466255.1
sarcolemma associated protein
chr4_-_99578776 0.20 ENST00000515287.1
tetraspanin 5
chr5_+_43033818 0.20 ENST00000607830.1
CTD-2035E11.4
chr2_+_89952792 0.20 ENST00000390265.2
immunoglobulin kappa variable 1D-33
chr1_+_149858461 0.19 ENST00000331380.2
histone cluster 2, H2ac
chr12_+_122064673 0.19 ENST00000537188.1
ORAI calcium release-activated calcium modulator 1
chr16_-_54972581 0.19 ENST00000559802.1
ENST00000558156.1
CTD-3032H12.1
chr6_-_26199471 0.19 ENST00000341023.1
histone cluster 1, H2ad
chr7_-_64023441 0.19 ENST00000309683.6
zinc finger protein 680
chr2_-_172750733 0.19 ENST00000392592.4
ENST00000422440.2
solute carrier family 25 (aspartate/glutamate carrier), member 12
chr17_-_26127525 0.19 ENST00000313735.6
nitric oxide synthase 2, inducible
chr1_-_60392452 0.18 ENST00000371204.3
cytochrome P450, family 2, subfamily J, polypeptide 2
chr1_-_8000872 0.18 ENST00000377507.3
tumor necrosis factor receptor superfamily, member 9
chr6_-_26199499 0.18 ENST00000377831.5
histone cluster 1, H3d
chr3_+_44596679 0.18 ENST00000426540.1
ENST00000431636.1
ENST00000341840.3
ENST00000273320.3
zinc finger with KRAB and SCAN domains 7
chr3_+_186648507 0.18 ENST00000458216.1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr7_+_22766766 0.18 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
interleukin 6 (interferon, beta 2)
chr2_+_169658928 0.18 ENST00000317647.7
ENST00000445023.2
nitric oxide synthase trafficking
chrX_-_119693745 0.18 ENST00000371323.2
cullin 4B
chr3_-_87039662 0.18 ENST00000494229.1
vestigial like 3 (Drosophila)
chr1_+_116654376 0.18 ENST00000369500.3
mab-21-like 3 (C. elegans)
chr1_+_147013182 0.18 ENST00000234739.3
B-cell CLL/lymphoma 9
chr11_+_123325106 0.18 ENST00000525757.1
long intergenic non-protein coding RNA 1059
chr22_-_32341336 0.18 ENST00000248984.3
chromosome 22 open reading frame 24
chr12_-_76461249 0.18 ENST00000551524.1
nucleosome assembly protein 1-like 1
chr2_+_136343943 0.18 ENST00000409606.1
R3H domain containing 1
chr1_+_32538492 0.18 ENST00000336294.5
transmembrane protein 39B
chr11_-_3013497 0.18 ENST00000448187.1
ENST00000532325.2
ENST00000399614.2
nucleosome assembly protein 1-like 4
chr10_-_93669233 0.18 ENST00000311575.5
fibroblast growth factor binding protein 3
chr22_+_46449674 0.18 ENST00000381051.2
hsa-mir-4763
chr8_+_1919481 0.18 ENST00000518539.2
KBTBD11 overlapping transcript 1 (non-protein coding)
chr4_-_100065440 0.18 ENST00000508393.1
ENST00000265512.7
alcohol dehydrogenase 4 (class II), pi polypeptide
chr20_+_39657454 0.17 ENST00000361337.2
topoisomerase (DNA) I
chr19_-_50169064 0.17 ENST00000593337.1
ENST00000598808.1
ENST00000600453.1
ENST00000593818.1
ENST00000597198.1
ENST00000601809.1
ENST00000377139.3
interferon regulatory factor 3
chr7_-_27205136 0.17 ENST00000396345.1
ENST00000343483.6
homeobox A9
chrX_+_16141667 0.17 ENST00000380289.2
gastrin-releasing peptide receptor
chr1_+_117544366 0.17 ENST00000256652.4
ENST00000369470.1
CD101 molecule
chr16_+_30934376 0.17 ENST00000562798.1
ENST00000471231.2
F-box and leucine-rich repeat protein 19
chr7_+_89975979 0.17 ENST00000257659.8
ENST00000222511.6
ENST00000417207.1
GTP-binding protein 10 (putative)
chr19_+_35417798 0.17 ENST00000303586.7
ENST00000439785.1
ENST00000601540.1
zinc finger protein 30
chr14_-_24017647 0.17 ENST00000555334.1
zinc finger homeobox 2
chr7_-_83824169 0.17 ENST00000265362.4
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr16_+_23847355 0.17 ENST00000498058.1
protein kinase C, beta
chrX_-_149999722 0.17 ENST00000418547.1
CD99 molecule-like 2
chrY_+_2803322 0.17 ENST00000383052.1
ENST00000155093.3
ENST00000449237.1
ENST00000443793.1
zinc finger protein, Y-linked
chr19_+_14693888 0.17 ENST00000547437.1
ENST00000397439.2
ENST00000417570.1
C-type lectin domain family 17, member A

Network of associatons between targets according to the STRING database.

First level regulatory network of POU5F1_POU2F3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 0.6 GO:0002251 innate immune response in mucosa(GO:0002227) organ or tissue specific immune response(GO:0002251) mucosal immune response(GO:0002385) antibacterial humoral response(GO:0019731)
0.2 0.9 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.2 0.6 GO:1901253 negative regulation of dendritic cell cytokine production(GO:0002731) negative regulation of intracellular transport of viral material(GO:1901253)
0.2 2.3 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.2 1.2 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.2 2.3 GO:0035290 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.1 0.3 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.1 1.0 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.5 GO:1903823 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.1 0.8 GO:0035234 ectopic germ cell programmed cell death(GO:0035234) negative regulation of adiponectin secretion(GO:0070164)
0.1 0.3 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.1 0.3 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.1 0.4 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.1 1.1 GO:0030223 neutrophil differentiation(GO:0030223)
0.1 0.5 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.1 0.3 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.2 GO:0001878 response to yeast(GO:0001878)
0.1 0.2 GO:0030187 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
0.1 6.2 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 0.2 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.1 0.2 GO:0043375 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 0.2 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.1 0.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 4.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 0.2 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.2 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.4 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.3 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0 0.1 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.0 0.2 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.0 0.3 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.0 GO:0090402 senescence-associated heterochromatin focus assembly(GO:0035986) oncogene-induced cell senescence(GO:0090402)
0.0 0.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.4 GO:0042756 drinking behavior(GO:0042756)
0.0 0.3 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0003357 noradrenergic neuron differentiation(GO:0003357)
0.0 0.2 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.0 0.2 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180) negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.2 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
0.0 0.1 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 0.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.7 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.1 GO:0061034 olfactory bulb mitral cell layer development(GO:0061034)
0.0 0.1 GO:0002432 granuloma formation(GO:0002432)
0.0 0.6 GO:0021794 thalamus development(GO:0021794)
0.0 0.3 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.1 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.1 GO:0030111 regulation of Wnt signaling pathway(GO:0030111)
0.0 0.0 GO:1900195 positive regulation of oocyte maturation(GO:1900195)
0.0 0.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.0 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.0 0.2 GO:0018032 protein amidation(GO:0018032)
0.0 0.1 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.1 GO:1903998 regulation of eating behavior(GO:1903998)
0.0 0.1 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.1 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.0 0.3 GO:0051013 microtubule severing(GO:0051013)
0.0 0.3 GO:0071888 MDA-5 signaling pathway(GO:0039530) macrophage apoptotic process(GO:0071888)
0.0 0.1 GO:0061145 bronchus cartilage development(GO:0060532) lung smooth muscle development(GO:0061145)
0.0 0.2 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.1 GO:0060489 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.0 0.1 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.0 0.1 GO:0010710 regulation of collagen catabolic process(GO:0010710)
0.0 0.0 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.0 0.1 GO:1904586 response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.0 0.3 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.1 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.0 0.1 GO:2000691 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.1 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.2 GO:0051712 positive regulation of killing of cells of other organism(GO:0051712)
0.0 0.1 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.2 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.3 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.0 0.1 GO:0009441 glycolate metabolic process(GO:0009441)
0.0 0.1 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 0.1 GO:0009988 cell-cell recognition(GO:0009988)
0.0 0.0 GO:0045720 negative regulation of integrin biosynthetic process(GO:0045720)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.1 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
0.0 0.1 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.0 0.2 GO:0045627 positive regulation of T-helper 1 cell differentiation(GO:0045627)
0.0 0.2 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.1 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.0 0.2 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 0.2 GO:0060536 cartilage morphogenesis(GO:0060536)
0.0 0.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.2 GO:0010255 hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255)
0.0 0.3 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.2 GO:0035494 SNARE complex disassembly(GO:0035494)
0.0 0.3 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.1 GO:0071306 regulation of cholesterol transporter activity(GO:0060694) cellular response to vitamin E(GO:0071306) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.2 GO:0000821 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
0.0 0.9 GO:0010390 histone monoubiquitination(GO:0010390)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.1 GO:0090258 negative regulation of mitochondrial fission(GO:0090258) neurofibrillary tangle assembly(GO:1902988)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.0 0.2 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.5 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.0 0.0 GO:1903217 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.0 0.1 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.3 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0006601 creatine biosynthetic process(GO:0006601)
0.0 0.7 GO:0007140 male meiosis(GO:0007140)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.0 GO:0006043 glucosamine catabolic process(GO:0006043)
0.0 0.1 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.0 GO:0051097 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.1 GO:0018277 protein deamination(GO:0018277)
0.0 0.4 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.6 GO:0006582 melanin metabolic process(GO:0006582)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 1.5 GO:0006342 chromatin silencing(GO:0006342)
0.0 0.1 GO:0046440 L-lysine catabolic process to acetyl-CoA(GO:0019474) L-lysine catabolic process(GO:0019477) L-lysine metabolic process(GO:0046440)
0.0 0.2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.1 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.1 GO:1901073 N-acetylglucosamine biosynthetic process(GO:0006045) glucosamine-containing compound biosynthetic process(GO:1901073)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.0 GO:0086097 renin-angiotensin regulation of aldosterone production(GO:0002018) phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.0 0.0 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.2 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.1 GO:0015862 uridine transport(GO:0015862) pyrimidine nucleoside transport(GO:0015864)
0.0 0.0 GO:0048104 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
0.0 0.1 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:1901894 regulation of calcium-transporting ATPase activity(GO:1901894)
0.0 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.2 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.1 GO:0097368 histone H4-K20 trimethylation(GO:0034773) establishment of Sertoli cell barrier(GO:0097368)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.3 GO:2000811 negative regulation of anoikis(GO:2000811)
0.0 0.0 GO:0052363 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.0 0.3 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.0 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1990923 PET complex(GO:1990923)
0.1 0.7 GO:0071953 elastic fiber(GO:0071953)
0.1 0.2 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.1 GO:0097444 spine apparatus(GO:0097444)
0.0 7.8 GO:0072562 blood microparticle(GO:0072562)
0.0 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.5 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0034677 integrin alpha7-beta1 complex(GO:0034677)
0.0 0.3 GO:0000798 nuclear cohesin complex(GO:0000798)
0.0 0.3 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.1 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.0 0.6 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 0.6 GO:0005771 multivesicular body(GO:0005771)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0042627 chylomicron(GO:0042627)
0.0 0.2 GO:0046930 pore complex(GO:0046930)
0.0 0.3 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.0 GO:0000126 transcription factor TFIIIB complex(GO:0000126)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.1 GO:0033093 Weibel-Palade body(GO:0033093)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.8 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.5 GO:0055100 adiponectin binding(GO:0055100)
0.1 2.3 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.4 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.1 2.3 GO:0070403 NAD+ binding(GO:0070403)
0.1 0.3 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.1 0.3 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.1 0.2 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.1 0.2 GO:0004145 diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808)
0.0 0.1 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
0.0 0.1 GO:0019115 benzaldehyde dehydrogenase activity(GO:0019115)
0.0 0.1 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 0.4 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.2 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.3 GO:0004522 ribonuclease A activity(GO:0004522)
0.0 0.8 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.2 GO:0001601 peptide YY receptor activity(GO:0001601)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.2 GO:0004517 nitric-oxide synthase activity(GO:0004517) tetrahydrobiopterin binding(GO:0034617)
0.0 0.2 GO:0042806 fucose binding(GO:0042806)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.5 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.0 GO:0035325 Toll-like receptor binding(GO:0035325)
0.0 0.2 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.2 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.1 GO:0016768 spermine synthase activity(GO:0016768)
0.0 0.2 GO:0042835 BRE binding(GO:0042835)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0033265 choline binding(GO:0033265)
0.0 6.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.2 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.2 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 1.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.1 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.0 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.5 GO:0051400 BH domain binding(GO:0051400)
0.0 0.3 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 0.1 GO:0015068 amidinotransferase activity(GO:0015067) glycine amidinotransferase activity(GO:0015068)
0.0 0.4 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.1 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.0 0.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.1 GO:0010736 serum response element binding(GO:0010736)
0.0 0.5 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.0 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.0 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.1 GO:0009384 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761) N-acylmannosamine kinase activity(GO:0009384)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.0 0.0 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.0 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.0 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.0 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.0 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.1 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.1 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.0 GO:0001026 TFIIIB-type transcription factor activity(GO:0001026)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.0 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID IL27 PATHWAY IL27-mediated signaling events
0.0 1.2 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.6 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 3.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.7 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.2 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.6 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 0.9 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.8 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 1.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.5 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism