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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for POU2F2_POU3F1

Z-value: 1.39

Motif logo

Transcription factors associated with POU2F2_POU3F1

Gene Symbol Gene ID Gene Info
ENSG00000028277.16 POU class 2 homeobox 2
ENSG00000185668.5 POU class 3 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU2F2hg19_v2_chr19_-_42636543_42636607-0.384.6e-01Click!

Activity profile of POU2F2_POU3F1 motif

Sorted Z-values of POU2F2_POU3F1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_228645796 3.49 ENST00000369160.2
histone cluster 3, H2bb
chr6_-_26124138 1.85 ENST00000314332.5
ENST00000396984.1
histone cluster 1, H2bc
chr17_+_19091325 1.84 ENST00000584923.1
small nucleolar RNA, C/D box 3A
chr1_+_149858461 1.15 ENST00000331380.2
histone cluster 2, H2ac
chr7_-_27153454 1.12 ENST00000522456.1
homeobox A3
chr1_-_149783914 1.11 ENST00000369167.1
ENST00000427880.2
ENST00000545683.1
histone cluster 2, H2bf
chr6_-_26043885 1.02 ENST00000357905.2
histone cluster 1, H2bb
chr17_-_7832753 1.01 ENST00000303790.2
potassium voltage-gated channel, shaker-related subfamily, beta member 3
chr6_-_27775694 0.96 ENST00000377401.2
histone cluster 1, H2bl
chr6_+_26217159 0.96 ENST00000303910.2
histone cluster 1, H2ae
chr6_+_31588478 0.93 ENST00000376007.4
ENST00000376033.2
proline-rich coiled-coil 2A
chr17_-_19015945 0.90 ENST00000573866.2
small nucleolar RNA, C/D box 3D
chr2_+_47922958 0.90 ENST00000606499.1
mutS homolog 6
chr9_-_35658007 0.84 ENST00000602361.1
RNA component of mitochondrial RNA processing endoribonuclease
chr5_+_2752216 0.72 ENST00000457752.2
chromosome 5 open reading frame 38
chr19_+_3572758 0.71 ENST00000416526.1
high mobility group 20B
chr16_-_73082274 0.71 ENST00000268489.5
zinc finger homeobox 3
chr6_-_27100529 0.65 ENST00000607124.1
ENST00000339812.2
ENST00000541790.1
histone cluster 1, H2bj
chr19_-_44124019 0.65 ENST00000300811.3
zinc finger protein 428
chrX_-_55020511 0.63 ENST00000375006.3
ENST00000374992.2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr19_-_50143452 0.62 ENST00000246792.3
related RAS viral (r-ras) oncogene homolog
chr12_-_58212487 0.60 ENST00000549994.1
advillin
chr6_-_53013620 0.58 ENST00000259803.7
glial cells missing homolog 1 (Drosophila)
chr6_-_138820624 0.58 ENST00000343505.5
NHS-like 1
chr6_+_27861190 0.57 ENST00000303806.4
histone cluster 1, H2bo
chr8_-_42396185 0.55 ENST00000518717.1
solute carrier family 20 (phosphate transporter), member 2
chr16_-_30107491 0.53 ENST00000566134.1
ENST00000565110.1
ENST00000398841.1
ENST00000398838.4
yippee-like 3 (Drosophila)
chr19_+_17516624 0.50 ENST00000596322.1
ENST00000600008.1
ENST00000601885.1
CTD-2521M24.9
chr14_-_68283291 0.50 ENST00000555452.1
ENST00000347230.4
zinc finger, FYVE domain containing 26
chr19_-_4791219 0.46 ENST00000598782.1
AC005523.3
chr19_-_44123734 0.46 ENST00000598676.1
zinc finger protein 428
chr14_-_106994333 0.45 ENST00000390624.2
immunoglobulin heavy variable 3-48
chr19_+_56111680 0.45 ENST00000301073.3
zinc finger protein 524
chr16_-_21314360 0.44 ENST00000219599.3
ENST00000576703.1
crystallin, mu
chr1_+_149822620 0.44 ENST00000369159.2
histone cluster 2, H2aa4
chr19_+_19144666 0.43 ENST00000535288.1
ENST00000538663.1
armadillo repeat containing 6
chr19_-_45982076 0.43 ENST00000423698.2
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr19_+_19144384 0.43 ENST00000392335.2
ENST00000535612.1
ENST00000537263.1
ENST00000540707.1
ENST00000541725.1
ENST00000269932.6
ENST00000546344.1
ENST00000540792.1
ENST00000536098.1
ENST00000541898.1
ENST00000543877.1
armadillo repeat containing 6
chr20_+_33292068 0.43 ENST00000374810.3
ENST00000374809.2
ENST00000451665.1
tumor protein p53 inducible nuclear protein 2
chr16_-_11730213 0.42 ENST00000576334.1
ENST00000574848.1
lipopolysaccharide-induced TNF factor
chr16_-_88752889 0.41 ENST00000332281.5
snail family zinc finger 3
chr12_+_7053228 0.41 ENST00000540506.2
chromosome 12 open reading frame 57
chr22_-_43010859 0.39 ENST00000339677.6
polymerase (DNA-directed), delta interacting protein 3
chr19_-_46088068 0.38 ENST00000263275.4
ENST00000323060.3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr3_-_87039662 0.38 ENST00000494229.1
vestigial like 3 (Drosophila)
chr2_+_90192768 0.38 ENST00000390275.2
immunoglobulin kappa variable 1D-13
chr10_+_24528108 0.37 ENST00000438429.1
KIAA1217
chr12_-_51611477 0.36 ENST00000389243.4
POU class 6 homeobox 1
chr7_+_26438187 0.35 ENST00000439120.1
ENST00000430548.1
ENST00000421862.1
ENST00000449537.1
ENST00000420774.1
ENST00000418758.2
AC004540.5
chr12_-_120189900 0.35 ENST00000546026.1
citron (rho-interacting, serine/threonine kinase 21)
chr5_+_158527630 0.35 ENST00000523301.1
RP11-175K6.1
chr16_-_74808710 0.35 ENST00000219368.3
ENST00000544337.1
fatty acid 2-hydroxylase
chr18_-_74839891 0.35 ENST00000581878.1
myelin basic protein
chr7_+_18535346 0.34 ENST00000405010.3
ENST00000406451.4
ENST00000428307.2
histone deacetylase 9
chr17_+_76037081 0.34 ENST00000588549.1
trinucleotide repeat containing 6C
chr12_+_7052974 0.34 ENST00000544681.1
ENST00000537087.1
chromosome 12 open reading frame 57
chr11_-_64085533 0.33 ENST00000544844.1
tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr19_-_40791302 0.33 ENST00000392038.2
ENST00000578123.1
v-akt murine thymoma viral oncogene homolog 2
chrX_-_106960285 0.33 ENST00000503515.1
ENST00000372397.2
TSC22 domain family, member 3
chr14_-_51297360 0.33 ENST00000496749.1
ninein (GSK3B interacting protein)
chr22_-_43010928 0.32 ENST00000348657.2
ENST00000252115.5
polymerase (DNA-directed), delta interacting protein 3
chr22_+_38093005 0.32 ENST00000406386.3
TRIO and F-actin binding protein
chr22_+_32750872 0.32 ENST00000397468.1
ret finger protein-like 3
chr20_-_44298878 0.31 ENST00000324384.3
ENST00000356562.2
WAP four-disulfide core domain 11
chr6_+_26273144 0.31 ENST00000377733.2
histone cluster 1, H2bi
chr6_+_27782788 0.31 ENST00000359465.4
histone cluster 1, H2bm
chr1_-_149859466 0.30 ENST00000331128.3
histone cluster 2, H2ab
chr19_+_41305330 0.30 ENST00000593972.1
egl-9 family hypoxia-inducible factor 2
chr6_+_26183958 0.30 ENST00000356530.3
histone cluster 1, H2be
chr3_+_187957646 0.30 ENST00000457242.1
LIM domain containing preferred translocation partner in lipoma
chr6_-_10415218 0.30 ENST00000466073.1
ENST00000498450.1
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr15_+_67458357 0.30 ENST00000537194.2
SMAD family member 3
chr1_+_32538492 0.30 ENST00000336294.5
transmembrane protein 39B
chr12_+_14369524 0.30 ENST00000538329.1
RP11-134N1.2
chr5_+_158527485 0.29 ENST00000517335.1
RP11-175K6.1
chr22_+_45680822 0.29 ENST00000216211.4
ENST00000396082.2
uroplakin 3A
chr19_-_19144243 0.29 ENST00000594445.1
ENST00000452918.2
ENST00000600377.1
ENST00000337018.6
SURP and G patch domain containing 2
chr12_+_7053172 0.29 ENST00000229281.5
chromosome 12 open reading frame 57
chr21_+_38792602 0.29 ENST00000398960.2
ENST00000398956.2
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr9_+_92219919 0.28 ENST00000252506.6
ENST00000375769.1
growth arrest and DNA-damage-inducible, gamma
chr4_-_156297919 0.28 ENST00000450097.1
microtubule-associated protein 9
chr1_+_201979645 0.28 ENST00000367284.5
ENST00000367283.3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr19_+_41305085 0.28 ENST00000303961.4
egl-9 family hypoxia-inducible factor 2
chr1_+_32538520 0.28 ENST00000438825.1
ENST00000456834.2
ENST00000373634.4
ENST00000427288.1
transmembrane protein 39B
chr2_+_66918558 0.27 ENST00000435389.1
ENST00000428590.1
ENST00000412944.1
AC007392.3
chr11_+_64085560 0.27 ENST00000265462.4
ENST00000352435.4
ENST00000347941.4
peroxiredoxin 5
chr14_+_93389425 0.27 ENST00000216492.5
ENST00000334654.4
chromogranin A (parathyroid secretory protein 1)
chr5_+_158654712 0.27 ENST00000520323.1
CTB-11I22.2
chr4_+_184826418 0.27 ENST00000308497.4
ENST00000438269.1
storkhead box 2
chr19_+_42788172 0.26 ENST00000160740.3
capicua transcriptional repressor
chr19_-_40791160 0.26 ENST00000358335.5
v-akt murine thymoma viral oncogene homolog 2
chr16_+_2198604 0.26 ENST00000210187.6
RAB26, member RAS oncogene family
chr10_-_29811456 0.26 ENST00000535393.1
supervillin
chr17_+_26638667 0.26 ENST00000600595.1
Uncharacterized protein
chr11_+_74699942 0.25 ENST00000526068.1
ENST00000532963.1
ENST00000531619.1
ENST00000534628.1
ENST00000545272.1
sialidase 3 (membrane sialidase)
chr10_-_10504285 0.25 ENST00000602311.1
RP11-271F18.4
chr1_-_149814478 0.24 ENST00000369161.3
histone cluster 2, H2aa3
chr6_-_10415470 0.24 ENST00000379604.2
ENST00000379613.3
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr5_+_158527667 0.24 ENST00000499583.1
RP11-175K6.1
chr1_+_17575584 0.24 ENST00000375460.3
peptidyl arginine deiminase, type III
chr7_-_44122063 0.24 ENST00000335195.6
ENST00000395831.3
ENST00000414235.1
ENST00000452049.1
ENST00000242248.5
polymerase (DNA directed), mu
chr12_+_72080253 0.24 ENST00000549735.1
transmembrane protein 19
chr1_+_28099700 0.24 ENST00000440806.2
syntaxin 12
chr9_+_136325089 0.23 ENST00000291722.7
ENST00000316948.4
ENST00000540581.1
calcium channel flower domain containing 1
chr7_-_100183742 0.23 ENST00000310300.6
leucine-rich repeats and calponin homology (CH) domain containing 4
chr3_-_87040259 0.23 ENST00000383698.3
vestigial like 3 (Drosophila)
chr6_-_128222103 0.23 ENST00000434358.1
ENST00000543064.1
ENST00000368248.2
thymocyte selection associated
chr5_+_60628074 0.23 ENST00000252744.5
zinc finger, SWIM-type containing 6
chr4_-_187517928 0.23 ENST00000512772.1
FAT atypical cadherin 1
chr11_-_64084959 0.23 ENST00000535750.1
ENST00000535126.1
ENST00000539854.1
ENST00000308774.2
tRNA methyltransferase 11-2 homolog (S. cerevisiae)
chr2_+_220143989 0.22 ENST00000336576.5
DnaJ (Hsp40) homolog, subfamily B, member 2
chr17_+_38497640 0.22 ENST00000394086.3
retinoic acid receptor, alpha
chr12_+_107712173 0.22 ENST00000280758.5
ENST00000420571.2
BTB (POZ) domain containing 11
chr16_+_3019309 0.22 ENST00000576565.1
progestin and adipoQ receptor family member IV
chr7_+_18535321 0.22 ENST00000413380.1
ENST00000430454.1
histone deacetylase 9
chrX_+_38660682 0.22 ENST00000457894.1
MID1 interacting protein 1
chr7_-_14029283 0.22 ENST00000433547.1
ENST00000405192.2
ets variant 1
chr5_-_39462390 0.22 ENST00000511792.1
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr1_+_156052354 0.21 ENST00000368301.2
lamin A/C
chr11_-_3663502 0.21 ENST00000359918.4
ADP-ribosyltransferase 5
chr12_-_11091862 0.21 ENST00000537503.1
taste receptor, type 2, member 14
chr17_+_42925270 0.21 ENST00000253410.2
ENST00000587021.1
HIG1 hypoxia inducible domain family, member 1B
chr6_+_43139037 0.20 ENST00000265354.4
serum response factor (c-fos serum response element-binding transcription factor)
chr17_+_72426891 0.20 ENST00000392627.1
G protein-coupled receptor, family C, group 5, member C
chr1_+_24018269 0.20 ENST00000374550.3
ribosomal protein L11
chr7_+_100183927 0.20 ENST00000241071.6
ENST00000360609.2
F-box protein 24
chr19_-_3971050 0.20 ENST00000545797.2
ENST00000596311.1
death-associated protein kinase 3
chr2_-_239148599 0.20 ENST00000409182.1
ENST00000409002.3
ENST00000450098.1
ENST00000409356.1
ENST00000409160.3
ENST00000409574.1
ENST00000272937.5
hes family bHLH transcription factor 6
chr17_-_46682321 0.20 ENST00000225648.3
ENST00000484302.2
homeobox B6
chr15_-_89456593 0.19 ENST00000558029.1
ENST00000539437.1
ENST00000542878.1
ENST00000268151.7
ENST00000566497.1
milk fat globule-EGF factor 8 protein
chr19_-_47291843 0.19 ENST00000542575.2
solute carrier family 1 (neutral amino acid transporter), member 5
chr7_-_105332084 0.19 ENST00000472195.1
ataxin 7-like 1
chr1_+_206579736 0.19 ENST00000439126.1
SLIT-ROBO Rho GTPase activating protein 2
chr5_-_2751762 0.19 ENST00000302057.5
ENST00000382611.6
iroquois homeobox 2
chr2_-_863877 0.19 ENST00000415700.1
long intergenic non-protein coding RNA 1115
chr6_+_27833034 0.19 ENST00000357320.2
histone cluster 1, H2al
chr17_-_73127353 0.19 ENST00000580423.1
ENST00000578337.1
ENST00000582160.1
5', 3'-nucleotidase, cytosolic
chr19_-_18392422 0.19 ENST00000252818.3
jun D proto-oncogene
chr19_-_893200 0.19 ENST00000269814.4
ENST00000395808.3
ENST00000312090.6
ENST00000325464.1
mediator complex subunit 16
chr10_-_63995871 0.19 ENST00000315289.2
rhotekin 2
chr19_-_8373173 0.19 ENST00000537716.2
ENST00000301458.5
CD320 molecule
chr17_-_19651598 0.18 ENST00000570414.1
aldehyde dehydrogenase 3 family, member A1
chr6_-_27860956 0.18 ENST00000359611.2
histone cluster 1, H2am
chr17_+_73521763 0.18 ENST00000167462.5
ENST00000375227.4
ENST00000392550.3
ENST00000578363.1
ENST00000579392.1
lethal giant larvae homolog 2 (Drosophila)
chr8_-_33370607 0.18 ENST00000360742.5
ENST00000523305.1
TELO2 interacting protein 2
chr2_+_54785485 0.18 ENST00000333896.5
spectrin, beta, non-erythrocytic 1
chr12_-_122238464 0.18 ENST00000546227.1
ras homolog family member F (in filopodia)
chr3_+_186435065 0.18 ENST00000287611.2
ENST00000265023.4
kininogen 1
chr2_+_97426631 0.18 ENST00000377075.2
cyclin M4
chr8_-_16859690 0.17 ENST00000180166.5
fibroblast growth factor 20
chr19_+_3572925 0.17 ENST00000333651.6
ENST00000417382.1
ENST00000453933.1
ENST00000262949.7
high mobility group 20B
chr11_-_62369291 0.17 ENST00000278823.2
metastasis associated 1 family, member 2
chr1_-_209792111 0.17 ENST00000455193.1
laminin, beta 3
chrX_+_38660704 0.17 ENST00000378474.3
MID1 interacting protein 1
chr17_-_3794021 0.17 ENST00000381769.2
calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr18_-_52989217 0.17 ENST00000570287.2
transcription factor 4
chr3_-_165555200 0.17 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
butyrylcholinesterase
chr11_-_75917569 0.17 ENST00000322563.3
wingless-type MMTV integration site family, member 11
chr20_+_32150140 0.17 ENST00000344201.3
ENST00000346541.3
ENST00000397800.1
ENST00000397798.2
ENST00000492345.1
core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr2_+_241938255 0.17 ENST00000401884.1
ENST00000405547.3
ENST00000310397.8
ENST00000342631.6
sushi, nidogen and EGF-like domains 1
chr12_+_130646999 0.16 ENST00000539839.1
ENST00000229030.4
frizzled family receptor 10
chr17_-_19651668 0.16 ENST00000494157.2
ENST00000225740.6
aldehyde dehydrogenase 3 family, member A1
chr5_+_140593509 0.16 ENST00000341948.4
protocadherin beta 13
chr15_-_89456630 0.16 ENST00000268150.8
milk fat globule-EGF factor 8 protein
chr1_+_201979743 0.16 ENST00000446188.1
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr19_+_50169081 0.15 ENST00000246784.3
BCL2-like 12 (proline rich)
chr20_+_816695 0.15 ENST00000246100.3
family with sequence similarity 110, member A
chr3_+_98250743 0.15 ENST00000284311.3
G protein-coupled receptor 15
chr19_+_17337027 0.15 ENST00000601529.1
ENST00000600232.1
occludin/ELL domain containing 1
chr16_-_4164027 0.15 ENST00000572288.1
adenylate cyclase 9
chr2_-_239197201 0.15 ENST00000254658.3
period circadian clock 2
chr2_-_219906220 0.15 ENST00000458526.1
ENST00000409865.3
ENST00000410037.1
ENST00000457968.1
ENST00000436631.1
ENST00000341552.5
ENST00000441968.1
ENST00000295729.2
coiled-coil domain containing 108
chr6_+_155538093 0.14 ENST00000462408.2
T-cell lymphoma invasion and metastasis 2
chr16_-_19897455 0.14 ENST00000568214.1
ENST00000569479.1
G protein-coupled receptor, family C, group 5, member B
chr16_+_3019552 0.14 ENST00000572687.1
progestin and adipoQ receptor family member IV
chr19_-_1021113 0.14 ENST00000333175.5
ENST00000356663.3
transmembrane protein 259
chr2_-_225811747 0.14 ENST00000409592.3
dedicator of cytokinesis 10
chr15_+_91478493 0.14 ENST00000418476.2
unc-45 homolog A (C. elegans)
chr6_+_27775899 0.14 ENST00000358739.3
histone cluster 1, H2ai
chr10_+_123923205 0.13 ENST00000369004.3
ENST00000260733.3
transforming, acidic coiled-coil containing protein 2
chr17_-_73127826 0.13 ENST00000582170.1
ENST00000245552.2
5', 3'-nucleotidase, cytosolic
chr12_+_51317788 0.13 ENST00000550502.1
methyltransferase like 7A
chr1_-_6052463 0.13 ENST00000378156.4
nephronophthisis 4
chr2_-_239197238 0.13 ENST00000254657.3
period circadian clock 2
chr5_-_131879205 0.13 ENST00000231454.1
interleukin 5 (colony-stimulating factor, eosinophil)
chr4_+_159727272 0.13 ENST00000379346.3
folliculin interacting protein 2
chrX_+_154114635 0.13 ENST00000369446.2
coagulation factor VIII-associated 1
chr16_-_67867749 0.13 ENST00000566758.1
ENST00000445712.2
ENST00000219172.3
ENST00000564817.1
centromere protein T
chr5_-_175965008 0.13 ENST00000537487.1
ring finger protein 44
chr22_-_22221900 0.13 ENST00000215832.6
ENST00000398822.3
mitogen-activated protein kinase 1
chr19_-_41903161 0.13 ENST00000602129.1
ENST00000593771.1
ENST00000596905.1
ENST00000221233.4
exosome component 5
chr1_+_207669495 0.13 ENST00000367052.1
ENST00000367051.1
ENST00000367053.1
complement component (3b/4b) receptor 1 (Knops blood group)
chr2_+_3393453 0.13 ENST00000441983.1
trafficking protein particle complex 12
chr2_-_61108449 0.13 ENST00000439412.1
ENST00000452343.1
AC010733.4
chr17_-_19651654 0.13 ENST00000395555.3
aldehyde dehydrogenase 3 family, member A1
chrX_-_154688276 0.13 ENST00000369445.2
coagulation factor VIII-associated 3
chr10_-_103880209 0.13 ENST00000425280.1
LIM domain binding 1
chr17_-_73127778 0.13 ENST00000578407.1
5', 3'-nucleotidase, cytosolic
chr11_-_34379546 0.13 ENST00000435224.2
ankyrin repeat and BTB (POZ) domain containing 2
chr2_+_89952792 0.12 ENST00000390265.2
immunoglobulin kappa variable 1D-33

Network of associatons between targets according to the STRING database.

First level regulatory network of POU2F2_POU3F1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.2 1.0 GO:0036343 psychomotor behavior(GO:0036343)
0.2 0.7 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.2 1.3 GO:0000710 meiotic mismatch repair(GO:0000710)
0.1 0.6 GO:0060018 astrocyte fate commitment(GO:0060018)
0.1 1.1 GO:0010159 specification of organ position(GO:0010159)
0.1 0.6 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.1 0.5 GO:0021623 optic cup structural organization(GO:0003409) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.1 0.2 GO:0061145 bronchus cartilage development(GO:0060532) lung smooth muscle development(GO:0061145)
0.1 0.3 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.1 0.6 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 0.3 GO:1900738 dense core granule biogenesis(GO:0061110) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) positive regulation of relaxation of cardiac muscle(GO:1901899) regulation of dense core granule biogenesis(GO:2000705)
0.1 0.6 GO:0071486 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 0.3 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 0.2 GO:0072081 proximal/distal pattern formation involved in nephron development(GO:0072047) specification of nephron tubule identity(GO:0072081) pattern specification involved in metanephros development(GO:0072268)
0.1 0.3 GO:1904209 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 0.2 GO:0014016 neuroblast differentiation(GO:0014016)
0.1 0.3 GO:0030047 actin modification(GO:0030047)
0.1 0.1 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.1 0.2 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.0 0.2 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.0 0.2 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.2 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.3 GO:0019249 lactate biosynthetic process(GO:0019249) regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.0 0.2 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.3 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.0 0.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.2 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.1 GO:0019858 cytosine metabolic process(GO:0019858)
0.0 0.3 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.2 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.6 GO:0090343 positive regulation of cell aging(GO:0090343) positive regulation of cellular senescence(GO:2000774)
0.0 0.6 GO:0097475 motor neuron migration(GO:0097475)
0.0 6.6 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.2 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.7 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.9 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.3 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.2 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 0.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.3 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.7 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.2 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.1 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.0 0.3 GO:0015840 urea transport(GO:0015840)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0030222 eosinophil differentiation(GO:0030222)
0.0 0.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.4 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.1 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.3 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.1 GO:0032242 regulation of nucleoside transport(GO:0032242)
0.0 0.4 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.1 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.1 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.0 0.2 GO:1902571 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.2 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.0 0.0 GO:1905069 allantois development(GO:1905069)
0.0 0.4 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.1 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.0 0.2 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.1 GO:2001191 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.0 0.1 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 0.1 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.2 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.4 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0 0.4 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.0 GO:2000342 negative regulation of chemokine (C-X-C motif) ligand 2 production(GO:2000342)
0.0 0.2 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.2 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.3 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.4 GO:0090312 positive regulation of protein deacetylation(GO:0090312)
0.0 0.6 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.7 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.1 GO:0070141 response to UV-A(GO:0070141)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.0 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.5 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.2 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.2 GO:0031033 myosin filament organization(GO:0031033)
0.0 0.2 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 0.1 GO:0070561 vitamin D receptor signaling pathway(GO:0070561)
0.0 0.1 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.2 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.4 GO:0070584 mitochondrion morphogenesis(GO:0070584)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0032301 MutSalpha complex(GO:0032301)
0.1 8.8 GO:0000786 nucleosome(GO:0000786)
0.1 0.4 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.4 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559) cytoplasmic side of late endosome membrane(GO:0098560)
0.0 0.5 GO:0033269 internode region of axon(GO:0033269)
0.0 0.6 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.7 GO:0000346 transcription export complex(GO:0000346)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 0.2 GO:0032437 cuticular plate(GO:0032437)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.3 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0032143 single thymine insertion binding(GO:0032143)
0.1 0.6 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.4 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
0.1 0.2 GO:0015235 cobalamin transporter activity(GO:0015235)
0.1 0.6 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 0.2 GO:0033265 choline binding(GO:0033265)
0.1 0.4 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.1 0.2 GO:0001855 complement component C4b binding(GO:0001855)
0.1 1.2 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.4 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.2 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.2 GO:0010736 serum response element binding(GO:0010736)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.3 GO:0043426 MRF binding(GO:0043426)
0.0 0.5 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.4 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.0 0.3 GO:0001016 RNA polymerase III regulatory region DNA binding(GO:0001016) thioredoxin peroxidase activity(GO:0008379)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.3 GO:0045159 myosin II binding(GO:0045159)
0.0 0.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.2 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0 0.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:1904713 beta-catenin destruction complex binding(GO:1904713)
0.0 0.2 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.7 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.7 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.2 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.1 GO:0032396 HLA-A specific inhibitory MHC class I receptor activity(GO:0030107) HLA-B specific inhibitory MHC class I receptor activity(GO:0030109) inhibitory MHC class I receptor activity(GO:0032396)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity(GO:0004113)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 1.0 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 0.0 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 7.8 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 9.8 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.6 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.2 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis