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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for POU1F1

Z-value: 0.80

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Transcription factors associated with POU1F1

Gene Symbol Gene ID Gene Info
ENSG00000064835.6 POU class 1 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
POU1F1hg19_v2_chr3_-_87325728_87325739-0.542.7e-01Click!

Activity profile of POU1F1 motif

Sorted Z-values of POU1F1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_78359999 1.05 ENST00000550503.1
neuron navigator 3
chr18_-_59274139 0.88 ENST00000586949.1
RP11-879F14.2
chr8_-_124741451 0.73 ENST00000520519.1
annexin A13
chr2_+_242913327 0.66 ENST00000426962.1
AC093642.3
chr2_-_152118276 0.64 ENST00000409092.1
RNA binding motif protein 43
chr16_-_28634874 0.63 ENST00000395609.1
ENST00000350842.4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr3_-_191000172 0.58 ENST00000427544.2
urotensin 2B
chr18_-_74839891 0.58 ENST00000581878.1
myelin basic protein
chr7_+_13141097 0.56 ENST00000411542.1
AC011288.2
chr6_-_152639479 0.52 ENST00000356820.4
spectrin repeat containing, nuclear envelope 1
chr19_+_52873166 0.49 ENST00000424032.2
ENST00000600321.1
ENST00000344085.5
ENST00000597976.1
ENST00000422689.2
zinc finger protein 880
chr19_+_49199209 0.47 ENST00000522966.1
ENST00000425340.2
ENST00000391876.4
fucosyltransferase 2 (secretor status included)
chr13_-_81801115 0.46 ENST00000567258.1
long intergenic non-protein coding RNA 564
chr1_-_183538319 0.46 ENST00000420553.1
ENST00000419402.1
neutrophil cytosolic factor 2
chr12_-_52761262 0.45 ENST00000257901.3
keratin 85
chr9_-_95055923 0.45 ENST00000430417.1
isoleucyl-tRNA synthetase
chr11_-_111649074 0.43 ENST00000534218.1
RP11-108O10.2
chr12_-_85430024 0.42 ENST00000547836.1
ENST00000532498.2
tetraspanin 19
chr17_-_6524159 0.42 ENST00000589033.1
KIAA0753
chr4_+_3344141 0.41 ENST00000306648.7
regulator of G-protein signaling 12
chr6_-_26235206 0.41 ENST00000244534.5
histone cluster 1, H1d
chr15_-_72521017 0.40 ENST00000561609.1
pyruvate kinase, muscle
chr17_+_61086917 0.39 ENST00000424789.2
ENST00000389520.4
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr5_+_59783941 0.39 ENST00000506884.1
ENST00000504876.2
prostate androgen-regulated transcript 1 (non-protein coding)
chr1_+_81106951 0.37 ENST00000443565.1
RP5-887A10.1
chr14_-_92247032 0.36 ENST00000556661.1
ENST00000553676.1
ENST00000554560.1
catsper channel auxiliary subunit beta
chr15_+_58702742 0.36 ENST00000356113.6
ENST00000414170.3
lipase, hepatic
chr12_-_10282836 0.36 ENST00000304084.8
ENST00000353231.5
ENST00000525605.1
C-type lectin domain family 7, member A
chr7_+_134528635 0.36 ENST00000445569.2
caldesmon 1
chr2_+_20101786 0.34 ENST00000607190.1
RP11-79O8.1
chr21_-_43735628 0.34 ENST00000291525.10
ENST00000518498.1
trefoil factor 3 (intestinal)
chr19_-_36304201 0.34 ENST00000301175.3
proline dehydrogenase (oxidase) 2
chr22_+_23487513 0.34 ENST00000263116.2
ENST00000341989.4
RAB36, member RAS oncogene family
chr15_+_67418047 0.33 ENST00000540846.2
SMAD family member 3
chr1_+_117963209 0.33 ENST00000449370.2
mannosidase, alpha, class 1A, member 2
chr14_+_39944025 0.32 ENST00000554328.1
ENST00000556620.1
ENST00000557197.1
RP11-111A21.1
chr19_+_54466179 0.32 ENST00000270458.2
calcium channel, voltage-dependent, gamma subunit 8
chr21_-_27423339 0.32 ENST00000415997.1
amyloid beta (A4) precursor protein
chr11_+_12302492 0.32 ENST00000533534.1
MICAL C-terminal like
chr15_+_69365272 0.29 ENST00000559914.1
ENST00000558369.1
long intergenic non-protein coding RNA 277
chr22_-_32767017 0.29 ENST00000400234.1
RFPL3 antisense
chr12_+_47610315 0.29 ENST00000548348.1
ENST00000549500.1
PC-esterase domain containing 1B
chr19_+_13842559 0.29 ENST00000586600.1
coiled-coil domain containing 130
chr10_+_695888 0.29 ENST00000441152.2
proline rich 26
chr3_+_195447738 0.29 ENST00000447234.2
ENST00000320736.6
ENST00000436408.1
mucin 20, cell surface associated
chr15_+_101417919 0.29 ENST00000561338.1
aldehyde dehydrogenase 1 family, member A3
chr8_+_98900132 0.29 ENST00000520016.1
matrilin 2
chr9_-_33473882 0.28 ENST00000455041.2
ENST00000353159.2
ENST00000297990.4
ENST00000379471.2
nucleolar protein 6 (RNA-associated)
chr11_+_327171 0.28 ENST00000534483.1
ENST00000524824.1
ENST00000531076.1
RP11-326C3.12
chr6_+_131958436 0.27 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr19_-_22193731 0.27 ENST00000601773.1
ENST00000397126.4
ENST00000601993.1
ENST00000599916.1
zinc finger protein 208
chr15_-_34880646 0.27 ENST00000543376.1
golgin A8 family, member A
chr12_-_106480587 0.26 ENST00000548902.1
NUAK family, SNF1-like kinase, 1
chr12_-_25150409 0.26 ENST00000549262.1
chromosome 12 open reading frame 77
chr10_+_18549645 0.26 ENST00000396576.2
calcium channel, voltage-dependent, beta 2 subunit
chr6_+_29555683 0.26 ENST00000383640.2
olfactory receptor, family 2, subfamily H, member 2
chr9_-_28670283 0.25 ENST00000379992.2
leucine rich repeat and Ig domain containing 2
chr17_-_57158523 0.25 ENST00000581468.1
tripartite motif containing 37
chr6_+_158733692 0.25 ENST00000367094.2
ENST00000367097.3
tubby like protein 4
chr1_-_205091115 0.25 ENST00000264515.6
ENST00000367164.1
retinoblastoma binding protein 5
chr11_+_115498761 0.25 ENST00000424313.2
AP000997.1
chr12_-_86650077 0.25 ENST00000552808.2
ENST00000547225.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr3_-_20053741 0.24 ENST00000389050.4
protein phosphatase 2C-like domain containing 1
chr1_-_160924589 0.24 ENST00000368029.3
intelectin 2
chr17_+_78518617 0.24 ENST00000537330.1
ENST00000570891.1
regulatory associated protein of MTOR, complex 1
chrX_-_13835147 0.24 ENST00000493677.1
ENST00000355135.2
glycoprotein M6B
chr20_+_1099233 0.24 ENST00000246015.4
ENST00000335877.6
ENST00000438768.2
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chr3_-_52719546 0.24 ENST00000439181.1
ENST00000449505.1
polybromo 1
chr17_-_4938712 0.24 ENST00000254853.5
ENST00000424747.1
solute carrier family 52 (riboflavin transporter), member 1
chr17_-_72772462 0.24 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
N-acetyltransferase 9 (GCN5-related, putative)
chr2_+_232575168 0.24 ENST00000440384.1
prothymosin, alpha
chr19_+_9296279 0.24 ENST00000344248.2
olfactory receptor, family 7, subfamily D, member 2
chr2_-_27712583 0.24 ENST00000260570.3
ENST00000359466.6
ENST00000416524.2
intraflagellar transport 172 homolog (Chlamydomonas)
chr6_-_136788001 0.23 ENST00000544465.1
microtubule-associated protein 7
chr1_+_15668240 0.23 ENST00000444385.1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr19_+_19144384 0.23 ENST00000392335.2
ENST00000535612.1
ENST00000537263.1
ENST00000540707.1
ENST00000541725.1
ENST00000269932.6
ENST00000546344.1
ENST00000540792.1
ENST00000536098.1
ENST00000541898.1
ENST00000543877.1
armadillo repeat containing 6
chr19_+_16940198 0.23 ENST00000248054.5
ENST00000596802.1
ENST00000379803.1
SIN3 transcription regulator family member B
chr18_+_29027696 0.23 ENST00000257189.4
desmoglein 3
chr17_+_25799008 0.23 ENST00000583370.1
ENST00000398988.3
ENST00000268763.6
kinase suppressor of ras 1
chr22_-_43010928 0.23 ENST00000348657.2
ENST00000252115.5
polymerase (DNA-directed), delta interacting protein 3
chr10_+_17270214 0.23 ENST00000544301.1
vimentin
chr6_-_49712091 0.23 ENST00000371159.4
cysteine-rich secretory protein 3
chr11_-_128894053 0.23 ENST00000392657.3
Rho GTPase activating protein 32
chr14_+_61654271 0.23 ENST00000555185.1
ENST00000557294.1
ENST00000556778.1
protein kinase C, eta
chr6_+_4087664 0.23 ENST00000430835.2
chromosome 6 open reading frame 201
chr8_+_30244580 0.23 ENST00000523115.1
ENST00000519647.1
RNA binding protein with multiple splicing
chr6_+_26365443 0.22 ENST00000527422.1
ENST00000356386.2
ENST00000396934.3
ENST00000377708.2
ENST00000396948.1
ENST00000508906.2
butyrophilin, subfamily 3, member A2
chr10_-_28623368 0.22 ENST00000441595.2
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chrX_+_56590002 0.22 ENST00000338222.5
ubiquilin 2
chr8_-_145754428 0.22 ENST00000527462.1
ENST00000313465.5
ENST00000524821.1
chromosome 8 open reading frame 82
chr12_+_133066137 0.22 ENST00000434748.2
fibrosin-like 1
chr4_-_122085469 0.22 ENST00000057513.3
TNFAIP3 interacting protein 3
chr19_-_22193706 0.22 ENST00000597040.1
zinc finger protein 208
chr12_+_131438443 0.22 ENST00000261654.5
G protein-coupled receptor 133
chr3_+_52245458 0.22 ENST00000459884.1
aminolevulinate, delta-, synthase 1
chr19_+_21579958 0.21 ENST00000339914.6
ENST00000599461.1
zinc finger protein 493
chr7_+_13141010 0.21 ENST00000443947.1
AC011288.2
chr1_+_221051699 0.21 ENST00000366903.6
H2.0-like homeobox
chr12_+_12510352 0.21 ENST00000298571.6
loss of heterozygosity, 12, chromosomal region 1
chr19_-_4535233 0.21 ENST00000381848.3
ENST00000588887.1
ENST00000586133.1
perilipin 5
chr16_-_66583994 0.21 ENST00000564917.1
thymidine kinase 2, mitochondrial
chr15_-_72563585 0.21 ENST00000287196.9
ENST00000260376.7
poly (ADP-ribose) polymerase family, member 6
chr10_+_127585093 0.20 ENST00000368695.1
ENST00000368693.1
fibronectin type III and ankyrin repeat domains 1
chr17_+_76494911 0.20 ENST00000598378.1
DNAH17 antisense RNA 1
chr2_-_43266680 0.20 ENST00000425212.1
ENST00000422351.1
ENST00000449766.1
AC016735.2
chr17_+_1944790 0.20 ENST00000575162.1
diphthamide biosynthesis 1
chr12_-_11150474 0.20 ENST00000538986.1
taste receptor, type 2, member 20
chr12_-_67197760 0.20 ENST00000539540.1
ENST00000540433.1
ENST00000541947.1
ENST00000538373.1
glutamate receptor interacting protein 1
chr15_-_75748115 0.20 ENST00000360439.4
SIN3 transcription regulator family member A
chr1_+_149754227 0.20 ENST00000444948.1
ENST00000369168.4
Fc fragment of IgG, high affinity Ia, receptor (CD64)
chr2_-_190044480 0.20 ENST00000374866.3
collagen, type V, alpha 2
chr2_-_220264703 0.20 ENST00000519905.1
ENST00000523282.1
ENST00000434339.1
ENST00000457935.1
aspartyl aminopeptidase
chr6_+_114178512 0.19 ENST00000368635.4
myristoylated alanine-rich protein kinase C substrate
chr10_+_64133934 0.19 ENST00000395254.3
ENST00000395255.3
ENST00000410046.3
zinc finger protein 365
chr14_-_25479811 0.19 ENST00000550887.1
syntaxin binding protein 6 (amisyn)
chr10_-_74283694 0.19 ENST00000398763.4
ENST00000418483.2
ENST00000489666.2
mitochondrial calcium uptake 1
chr4_-_153601136 0.19 ENST00000504064.1
ENST00000304385.3
transmembrane protein 154
chr6_+_26087509 0.19 ENST00000397022.3
ENST00000353147.5
ENST00000352392.4
ENST00000349999.4
ENST00000317896.7
ENST00000357618.5
ENST00000470149.1
ENST00000336625.8
ENST00000461397.1
ENST00000488199.1
hemochromatosis
chr7_-_22862406 0.19 ENST00000372879.4
translocase of outer mitochondrial membrane 7 homolog (yeast)
chr7_-_84122033 0.18 ENST00000424555.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr5_+_111755280 0.18 ENST00000600409.1
EPB41L4A antisense RNA 2 (head to head)
chr9_-_21482312 0.18 ENST00000448696.3
interferon, epsilon
chr7_-_30009542 0.18 ENST00000438497.1
secernin 1
chr17_+_7155819 0.18 ENST00000570322.1
ENST00000576496.1
ENST00000574841.2
elongator acetyltransferase complex subunit 5
chr3_-_48130707 0.18 ENST00000360240.6
ENST00000383737.4
microtubule-associated protein 4
chr12_-_49581152 0.18 ENST00000550811.1
tubulin, alpha 1a
chr3_-_145940126 0.18 ENST00000498625.1
phospholipid scramblase 4
chr15_+_64386261 0.18 ENST00000560829.1
sorting nexin 1
chr2_+_208414985 0.18 ENST00000414681.1
cAMP responsive element binding protein 1
chr19_-_51920952 0.18 ENST00000356298.5
ENST00000339313.5
ENST00000529627.1
ENST00000439889.2
ENST00000353836.5
ENST00000432469.2
sialic acid binding Ig-like lectin 10
chr12_-_58220078 0.17 ENST00000549039.1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr16_-_2379688 0.17 ENST00000567910.1
ATP-binding cassette, sub-family A (ABC1), member 3
chr5_+_55147205 0.17 ENST00000396836.2
ENST00000396834.1
ENST00000447346.2
ENST00000359040.5
interleukin 31 receptor A
chr18_+_61445205 0.17 ENST00000431370.1
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr2_+_133874577 0.17 ENST00000596384.1
HCG2006742; Protein LOC100996685
chr12_-_71148413 0.17 ENST00000440835.2
ENST00000549308.1
ENST00000550661.1
protein tyrosine phosphatase, receptor type, R
chr6_+_106988986 0.16 ENST00000457437.1
ENST00000535438.1
absent in melanoma 1
chr20_+_3776371 0.16 ENST00000245960.5
cell division cycle 25B
chr1_+_168250194 0.16 ENST00000367821.3
T-box 19
chr19_-_43969796 0.16 ENST00000244333.3
LY6/PLAUR domain containing 3
chrX_-_55057403 0.16 ENST00000396198.3
ENST00000335854.4
ENST00000455688.1
ENST00000330807.5
aminolevulinate, delta-, synthase 2
chr17_+_6918354 0.16 ENST00000552775.1
chromosome 17 open reading frame 49
chr14_-_101295407 0.16 ENST00000596284.1
AL117190.2
chr17_-_72772425 0.16 ENST00000578822.1
N-acetyltransferase 9 (GCN5-related, putative)
chrX_+_70503526 0.16 ENST00000413858.1
ENST00000450092.1
non-POU domain containing, octamer-binding
chr17_+_66255310 0.15 ENST00000448504.2
arylsulfatase G
chr7_+_99425633 0.15 ENST00000354829.2
ENST00000421837.2
ENST00000417625.1
ENST00000342499.4
ENST00000444905.1
ENST00000415413.1
ENST00000312017.5
ENST00000222382.5
cytochrome P450, family 3, subfamily A, polypeptide 43
chr2_+_103035102 0.15 ENST00000264260.2
interleukin 18 receptor accessory protein
chr5_-_125930929 0.15 ENST00000553117.1
ENST00000447989.2
ENST00000409134.3
aldehyde dehydrogenase 7 family, member A1
chr17_+_8191815 0.15 ENST00000226105.6
ENST00000407006.4
ENST00000580434.1
ENST00000439238.3
RAN guanine nucleotide release factor
chr12_+_26348429 0.15 ENST00000242729.2
sarcospan
chr15_+_64680003 0.15 ENST00000261884.3
thyroid hormone receptor interactor 4
chr11_+_2405833 0.15 ENST00000527343.1
ENST00000464784.2
CD81 molecule
chr5_+_140593509 0.15 ENST00000341948.4
protocadherin beta 13
chr6_-_161695074 0.14 ENST00000457520.2
ENST00000366906.5
ENST00000320285.4
1-acylglycerol-3-phosphate O-acyltransferase 4
chr12_-_86650045 0.14 ENST00000604798.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr1_+_77333117 0.14 ENST00000477717.1
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr9_-_85882145 0.14 ENST00000328788.1
FERM domain containing 3
chr1_-_21377383 0.14 ENST00000374935.3
eukaryotic translation initiation factor 4 gamma, 3
chr6_-_49712072 0.14 ENST00000423399.2
cysteine-rich secretory protein 3
chr22_-_43010859 0.14 ENST00000339677.6
polymerase (DNA-directed), delta interacting protein 3
chr11_-_117186946 0.14 ENST00000313005.6
ENST00000528053.1
beta-site APP-cleaving enzyme 1
chr22_+_43011247 0.14 ENST00000602478.1
RNA, U12 small nuclear
chr9_+_117373486 0.14 ENST00000288502.4
ENST00000374049.4
chromosome 9 open reading frame 91
chr16_+_28565230 0.14 ENST00000317058.3
coiled-coil domain containing 101
chr5_-_94417186 0.14 ENST00000312216.8
ENST00000512425.1
multiple C2 domains, transmembrane 1
chr6_+_26087646 0.14 ENST00000309234.6
hemochromatosis
chr11_+_35201826 0.14 ENST00000531873.1
CD44 molecule (Indian blood group)
chr16_-_67217844 0.14 ENST00000563902.1
ENST00000561621.1
ENST00000290881.7
KIAA0895-like
chr7_-_144435985 0.14 ENST00000549981.1
thiamin pyrophosphokinase 1
chr4_+_169552748 0.13 ENST00000504519.1
ENST00000512127.1
palladin, cytoskeletal associated protein
chr19_+_49404041 0.13 ENST00000263273.5
ENST00000424608.1
nucleobindin 1
chr2_+_234826016 0.13 ENST00000324695.4
ENST00000433712.2
transient receptor potential cation channel, subfamily M, member 8
chr17_+_12569472 0.13 ENST00000343344.4
myocardin
chr1_-_91813006 0.13 ENST00000430465.1
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr5_-_94417314 0.13 ENST00000505208.1
multiple C2 domains, transmembrane 1
chr18_+_21269404 0.13 ENST00000313654.9
laminin, alpha 3
chr16_-_66584059 0.13 ENST00000417693.3
ENST00000544898.1
ENST00000569718.1
ENST00000527284.1
ENST00000299697.7
ENST00000451102.2
thymidine kinase 2, mitochondrial
chrX_-_13321511 0.13 ENST00000412485.1
ENST00000443965.1
GS1-600G8.5
chr16_-_28937027 0.13 ENST00000358201.4
rabaptin, RAB GTPase binding effector protein 2
chr2_-_219157219 0.13 ENST00000445635.1
ENST00000413976.1
transmembrane BAX inhibitor motif containing 1
chr16_-_70835034 0.12 ENST00000261776.5
Vac14 homolog (S. cerevisiae)
chrX_+_70503433 0.12 ENST00000276079.8
ENST00000373856.3
ENST00000373841.1
ENST00000420903.1
non-POU domain containing, octamer-binding
chr6_-_49712147 0.12 ENST00000433368.2
ENST00000354620.4
cysteine-rich secretory protein 3
chr6_-_25874440 0.12 ENST00000361703.6
ENST00000397060.4
solute carrier family 17 (organic anion transporter), member 3
chr16_-_66764119 0.12 ENST00000569320.1
dynein, cytoplasmic 1, light intermediate chain 2
chr1_+_8378140 0.12 ENST00000377479.2
solute carrier family 45, member 1
chr8_-_141774467 0.12 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
protein tyrosine kinase 2
chr5_-_94417562 0.12 ENST00000505465.1
multiple C2 domains, transmembrane 1
chr4_-_85654615 0.12 ENST00000514711.1
WD repeat and FYVE domain containing 3
chr5_-_36301984 0.12 ENST00000502994.1
ENST00000515759.1
ENST00000296604.3
RAN binding protein 3-like
chr8_-_38008783 0.12 ENST00000276449.4
steroidogenic acute regulatory protein
chr4_-_122854612 0.12 ENST00000264811.5
transient receptor potential cation channel, subfamily C, member 3
chr11_-_111649015 0.12 ENST00000529841.1
RP11-108O10.2
chr5_+_156696362 0.11 ENST00000377576.3
cytoplasmic FMR1 interacting protein 2
chr3_+_16216137 0.11 ENST00000339732.5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 15
chr7_+_129984630 0.11 ENST00000355388.3
ENST00000497503.1
ENST00000463587.1
ENST00000461828.1
ENST00000494311.1
ENST00000466363.2
ENST00000485477.1
ENST00000431780.2
ENST00000474905.1
carboxypeptidase A5
chr17_+_6918093 0.11 ENST00000439424.2
chromosome 17 open reading frame 49
chr3_+_159943362 0.11 ENST00000326474.3
chromosome 3 open reading frame 80
chr5_-_55412774 0.11 ENST00000434982.2
ankyrin repeat domain 55

Network of associatons between targets according to the STRING database.

First level regulatory network of POU1F1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.1 0.6 GO:1904207 regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904207) positive regulation of chemokine (C-C motif) ligand 2 secretion(GO:1904209)
0.1 0.3 GO:0060166 olfactory pit development(GO:0060166)
0.1 0.3 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.1 0.4 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.1 0.2 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.3 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.1 0.2 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.1 0.2 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.2 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.3 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.0 0.3 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.2 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.4 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.4 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
0.0 0.2 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
0.0 0.4 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.2 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.0 0.3 GO:0071233 cellular response to leucine(GO:0071233)
0.0 0.5 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.2 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.3 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.5 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.3 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:2000224 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
0.0 0.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.2 GO:0032907 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916) chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.4 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.0 0.1 GO:0043126 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.0 0.2 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.3 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 0.2 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.5 GO:0034310 primary alcohol catabolic process(GO:0034310)
0.0 0.1 GO:1902045 negative regulation of Fas signaling pathway(GO:1902045)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.2 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.4 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.1 GO:0086028 bundle of His cell to Purkinje myocyte signaling(GO:0086028) bundle of His cell action potential(GO:0086043)
0.0 0.1 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.1 GO:0000270 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.2 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.2 GO:0061525 hindgut development(GO:0061525)
0.0 0.1 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.2 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.2 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.1 GO:0009233 menaquinone metabolic process(GO:0009233)
0.0 0.1 GO:0015747 urate transport(GO:0015747)
0.0 0.3 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.1 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.4 GO:0045730 respiratory burst(GO:0045730)
0.0 0.0 GO:0032231 regulation of actin filament bundle assembly(GO:0032231) positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.1 GO:0048391 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.0 0.2 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.4 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.2 GO:0007144 female meiosis I(GO:0007144)
0.0 0.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.2 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1902912 pyruvate kinase complex(GO:1902912)
0.1 0.2 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.1 0.2 GO:0000806 Y chromosome(GO:0000806)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.6 GO:0033269 internode region of axon(GO:0033269)
0.0 0.2 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.4 GO:0032010 phagolysosome(GO:0032010)
0.0 0.2 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.3 GO:1990357 terminal web(GO:1990357)
0.0 0.4 GO:0036128 CatSper complex(GO:0036128)
0.0 1.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.1 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.0 0.3 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 0.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.2 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.1 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.0 0.3 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.4 GO:0000346 transcription export complex(GO:0000346)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 0.3 GO:0004657 proline dehydrogenase activity(GO:0004657)
0.1 0.2 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.1 0.5 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894) steroid sulfotransferase activity(GO:0050294)
0.1 0.4 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.1 0.4 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.2 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.1 0.3 GO:0035529 phosphodiesterase I activity(GO:0004528) NADH pyrophosphatase activity(GO:0035529)
0.0 0.4 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.3 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.0 0.6 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.7 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.2 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.3 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.2 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.2 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.2 GO:0035473 lipase binding(GO:0035473)
0.0 0.1 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.1 GO:0047017 geranylgeranyl reductase activity(GO:0045550) prostaglandin-F synthase activity(GO:0047017)
0.0 0.5 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activity(GO:0016175) superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.3 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.2 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.4 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.2 GO:0015266 protein channel activity(GO:0015266)
0.0 0.1 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.4 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0015562 urate transmembrane transporter activity(GO:0015143) efflux transmembrane transporter activity(GO:0015562) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.5 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.1 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 1.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.1 GO:0033038 bitter taste receptor activity(GO:0033038)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins