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A549 cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for PKNOX1_TGIF2

Z-value: 1.01

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Transcription factors associated with PKNOX1_TGIF2

Gene Symbol Gene ID Gene Info
PKNOX1
ENSG00000160199.10 PBX/knotted 1 homeobox 1
TGIF2
ENSG00000118707.5 TGFB induced factor homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TGIF2hg19_v2_chr20_+_35202909_352030750.701.2e-01Click!
PKNOX1hg19_v2_chr21_+_44394620_443947370.078.9e-01Click!

Activity profile of PKNOX1_TGIF2 motif

Sorted Z-values of PKNOX1_TGIF2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_39405939 0.68 ENST00000334109.2
KRTAP9-4
keratin associated protein 9-4
chr7_+_23210760 0.67 ENST00000366347.4
AC005082.1
Uncharacterized protein
chr9_-_134615326 0.59 ENST00000438647.1
RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr1_+_207262578 0.58 ENST00000243611.5
ENST00000367076.3
C4BPB
complement component 4 binding protein, beta
chr11_+_6411670 0.57 ENST00000530395.1
ENST00000527275.1
SMPD1
sphingomyelin phosphodiesterase 1, acid lysosomal
chr1_+_207262881 0.57 ENST00000451804.2
C4BPB
complement component 4 binding protein, beta
chr7_-_74867509 0.56 ENST00000426327.3
GATSL2
GATS protein-like 2
chr6_+_155334780 0.49 ENST00000538270.1
ENST00000535231.1
TIAM2
T-cell lymphoma invasion and metastasis 2
chr3_+_111260980 0.49 ENST00000438817.2
CD96
CD96 molecule
chr22_+_17082732 0.45 ENST00000558085.2
ENST00000592918.1
ENST00000400593.2
ENST00000592107.1
ENST00000426585.1
ENST00000591299.1
TPTEP1
transmembrane phosphatase with tensin homology pseudogene 1
chr7_+_70229899 0.43 ENST00000443672.1
AUTS2
autism susceptibility candidate 2
chr11_+_6411636 0.41 ENST00000299397.3
ENST00000356761.2
ENST00000342245.4
SMPD1
sphingomyelin phosphodiesterase 1, acid lysosomal
chr4_-_46391367 0.41 ENST00000503806.1
ENST00000356504.1
ENST00000514090.1
ENST00000506961.1
GABRA2
gamma-aminobutyric acid (GABA) A receptor, alpha 2
chr17_-_77967433 0.39 ENST00000571872.1
TBC1D16
TBC1 domain family, member 16
chr10_-_4720301 0.35 ENST00000449712.1
LINC00704
long intergenic non-protein coding RNA 704
chr19_+_36393367 0.35 ENST00000246551.4
HCST
hematopoietic cell signal transducer
chr13_+_24844857 0.33 ENST00000409126.1
ENST00000343003.6
SPATA13
spermatogenesis associated 13
chr22_+_20905269 0.33 ENST00000457322.1
MED15
mediator complex subunit 15
chr3_-_52719912 0.33 ENST00000420148.1
PBRM1
polybromo 1
chr18_+_54318893 0.33 ENST00000593058.1
WDR7
WD repeat domain 7
chr14_+_61995722 0.31 ENST00000556347.1
RP11-47I22.4
RP11-47I22.4
chr3_-_52719810 0.31 ENST00000424867.1
ENST00000394830.3
ENST00000431678.1
ENST00000450271.1
PBRM1
polybromo 1
chr2_-_192015697 0.31 ENST00000409995.1
STAT4
signal transducer and activator of transcription 4
chr4_-_175443788 0.31 ENST00000541923.1
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr6_+_41021027 0.31 ENST00000244669.2
APOBEC2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
chr11_+_827553 0.31 ENST00000528542.2
ENST00000450448.1
EFCAB4A
EF-hand calcium binding domain 4A
chr1_+_154966058 0.31 ENST00000392487.1
LENEP
lens epithelial protein
chr5_-_94620239 0.29 ENST00000515393.1
MCTP1
multiple C2 domains, transmembrane 1
chr16_-_79634595 0.29 ENST00000326043.4
ENST00000393350.1
MAF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr15_+_59908633 0.29 ENST00000559626.1
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr18_+_54318566 0.28 ENST00000589935.1
ENST00000357574.3
WDR7
WD repeat domain 7
chr1_+_186649754 0.28 ENST00000608917.1
RP5-973M2.2
RP5-973M2.2
chr17_-_65992544 0.27 ENST00000580729.1
RP11-855A2.5
RP11-855A2.5
chr19_+_9296279 0.27 ENST00000344248.2
OR7D2
olfactory receptor, family 7, subfamily D, member 2
chr2_-_190446738 0.27 ENST00000427419.1
ENST00000455320.1
SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr16_+_20817953 0.26 ENST00000568647.1
AC004381.6
Putative RNA exonuclease NEF-sp
chr3_-_52488048 0.26 ENST00000232975.3
TNNC1
troponin C type 1 (slow)
chr12_-_11036844 0.26 ENST00000428168.2
PRH1
proline-rich protein HaeIII subfamily 1
chr4_-_105416039 0.26 ENST00000394767.2
CXXC4
CXXC finger protein 4
chr7_-_99869799 0.26 ENST00000436886.2
GATS
GATS, stromal antigen 3 opposite strand
chr12_+_85430110 0.25 ENST00000393212.3
ENST00000393217.2
LRRIQ1
leucine-rich repeats and IQ motif containing 1
chr1_+_203765437 0.25 ENST00000550078.1
ZBED6
zinc finger, BED-type containing 6
chr17_-_29151686 0.24 ENST00000544695.1
CRLF3
cytokine receptor-like factor 3
chr18_-_44775554 0.24 ENST00000425639.1
ENST00000400404.1
SKOR2
SKI family transcriptional corepressor 2
chr2_+_29001711 0.24 ENST00000418910.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr16_+_20817746 0.24 ENST00000568894.1
AC004381.6
Putative RNA exonuclease NEF-sp
chr5_+_173763250 0.24 ENST00000515513.1
ENST00000507361.1
ENST00000510234.1
RP11-267A15.1
RP11-267A15.1
chr5_+_125758813 0.24 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr17_-_72358001 0.23 ENST00000375366.3
BTBD17
BTB (POZ) domain containing 17
chrY_-_21239221 0.23 ENST00000447937.1
ENST00000331787.2
TTTY14
testis-specific transcript, Y-linked 14 (non-protein coding)
chr1_-_179198806 0.22 ENST00000392043.3
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr22_+_20905422 0.22 ENST00000424287.1
ENST00000423862.1
MED15
mediator complex subunit 15
chr11_+_120207787 0.21 ENST00000397843.2
ENST00000356641.3
ARHGEF12
Rho guanine nucleotide exchange factor (GEF) 12
chr1_+_104104379 0.21 ENST00000435302.1
AMY2B
amylase, alpha 2B (pancreatic)
chr6_+_111195973 0.21 ENST00000368885.3
ENST00000368882.3
ENST00000451850.2
ENST00000368877.5
AMD1
adenosylmethionine decarboxylase 1
chr19_-_54604083 0.20 ENST00000391761.1
ENST00000356532.3
ENST00000359649.4
ENST00000358375.4
ENST00000391760.1
ENST00000351806.4
OSCAR
osteoclast associated, immunoglobulin-like receptor
chr1_-_145715565 0.20 ENST00000369288.2
ENST00000369290.1
ENST00000401557.3
CD160
CD160 molecule
chr12_+_69186125 0.20 ENST00000399333.3
AC124890.1
HCG1774533, isoform CRA_a; PRO2268; Uncharacterized protein
chr12_-_31882108 0.20 ENST00000281471.6
AMN1
antagonist of mitotic exit network 1 homolog (S. cerevisiae)
chr1_-_214638146 0.20 ENST00000543945.1
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr16_-_30569801 0.20 ENST00000395091.2
ZNF764
zinc finger protein 764
chr3_-_27764190 0.20 ENST00000537516.1
EOMES
eomesodermin
chr12_-_105478339 0.20 ENST00000424857.2
ENST00000258494.9
ALDH1L2
aldehyde dehydrogenase 1 family, member L2
chr5_+_125758865 0.20 ENST00000542322.1
ENST00000544396.1
GRAMD3
GRAM domain containing 3
chr5_+_125759140 0.20 ENST00000543198.1
GRAMD3
GRAM domain containing 3
chr16_-_30457048 0.20 ENST00000500504.2
ENST00000542752.1
SEPHS2
selenophosphate synthetase 2
chr17_-_34122596 0.19 ENST00000250144.8
MMP28
matrix metallopeptidase 28
chr17_-_8093471 0.19 ENST00000389017.4
C17orf59
chromosome 17 open reading frame 59
chr1_+_24285599 0.19 ENST00000471915.1
PNRC2
proline-rich nuclear receptor coactivator 2
chr10_-_99052382 0.19 ENST00000453547.2
ENST00000316676.8
ENST00000358308.3
ENST00000466484.1
ENST00000358531.4
ARHGAP19-SLIT1
ARHGAP19
ARHGAP19-SLIT1 readthrough (NMD candidate)
Rho GTPase activating protein 19
chr22_+_39052632 0.19 ENST00000411557.1
ENST00000396811.2
ENST00000216029.3
ENST00000416285.1
CBY1
chibby homolog 1 (Drosophila)
chr9_-_139345270 0.18 ENST00000398335.1
SEC16A
SEC16 homolog A (S. cerevisiae)
chr1_-_179198702 0.18 ENST00000502732.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr5_-_176449586 0.18 ENST00000509236.1
UIMC1
ubiquitin interaction motif containing 1
chr15_-_31283798 0.17 ENST00000435680.1
ENST00000425768.1
MTMR10
myotubularin related protein 10
chr2_-_74779744 0.17 ENST00000409249.1
LOXL3
lysyl oxidase-like 3
chr20_-_36156264 0.17 ENST00000445723.1
ENST00000414080.1
BLCAP
bladder cancer associated protein
chr6_-_163148780 0.16 ENST00000366892.1
ENST00000366898.1
ENST00000366897.1
ENST00000366896.1
PARK2
parkin RBR E3 ubiquitin protein ligase
chr15_-_76352069 0.16 ENST00000305435.10
ENST00000563910.1
NRG4
neuregulin 4
chr3_-_113160334 0.16 ENST00000393845.2
ENST00000295868.2
WDR52
WD repeat domain 52
chr4_+_146539415 0.16 ENST00000281317.5
MMAA
methylmalonic aciduria (cobalamin deficiency) cblA type
chr3_-_111852061 0.16 ENST00000488580.1
ENST00000460387.2
ENST00000484193.1
ENST00000487901.1
GCSAM
germinal center-associated, signaling and motility
chr5_-_66942617 0.16 ENST00000507298.1
RP11-83M16.5
RP11-83M16.5
chr5_-_154230130 0.16 ENST00000519501.1
ENST00000518651.1
ENST00000517938.1
ENST00000520461.1
FAXDC2
fatty acid hydroxylase domain containing 2
chr9_-_99180597 0.15 ENST00000375256.4
ZNF367
zinc finger protein 367
chr17_-_71223839 0.15 ENST00000579872.1
ENST00000580032.1
FAM104A
family with sequence similarity 104, member A
chr9_+_123906331 0.15 ENST00000431571.1
CNTRL
centriolin
chr15_-_37392086 0.15 ENST00000561208.1
MEIS2
Meis homeobox 2
chr15_+_43477455 0.15 ENST00000300213.4
CCNDBP1
cyclin D-type binding-protein 1
chr1_+_246729815 0.15 ENST00000366511.1
CNST
consortin, connexin sorting protein
chr4_+_3076388 0.15 ENST00000355072.5
HTT
huntingtin
chr2_+_242127924 0.15 ENST00000402530.3
ENST00000274979.8
ENST00000402430.3
ANO7
anoctamin 7
chr2_-_61765732 0.15 ENST00000443240.1
ENST00000436018.1
XPO1
exportin 1 (CRM1 homolog, yeast)
chr4_-_47983519 0.15 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
CNGA1
cyclic nucleotide gated channel alpha 1
chr17_-_34195862 0.14 ENST00000592980.1
ENST00000587626.1
C17orf66
chromosome 17 open reading frame 66
chr7_+_73442487 0.14 ENST00000380575.4
ENST00000380584.4
ENST00000458204.1
ENST00000357036.5
ENST00000417091.1
ENST00000429192.1
ENST00000442310.1
ENST00000380553.4
ENST00000380576.5
ENST00000428787.1
ENST00000320399.6
ELN
elastin
chr20_-_33872518 0.14 ENST00000374436.3
EIF6
eukaryotic translation initiation factor 6
chr4_-_175443484 0.14 ENST00000514584.1
ENST00000542498.1
ENST00000296521.7
ENST00000422112.2
ENST00000504433.1
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr6_-_31651817 0.14 ENST00000375863.3
ENST00000375860.2
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr3_+_185080908 0.14 ENST00000265026.3
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr6_-_28220002 0.14 ENST00000377294.2
ZKSCAN4
zinc finger with KRAB and SCAN domains 4
chr11_-_67415048 0.14 ENST00000529256.1
ACY3
aspartoacylase (aminocyclase) 3
chr3_+_38017264 0.14 ENST00000436654.1
CTDSPL
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr13_-_46716969 0.14 ENST00000435666.2
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr19_-_58951496 0.14 ENST00000254166.3
ZNF132
zinc finger protein 132
chr5_+_43603229 0.14 ENST00000344920.4
ENST00000512996.2
NNT
nicotinamide nucleotide transhydrogenase
chr2_+_113321939 0.13 ENST00000458012.2
POLR1B
polymerase (RNA) I polypeptide B, 128kDa
chr7_+_76139833 0.13 ENST00000257632.5
UPK3B
uroplakin 3B
chr3_-_142166846 0.13 ENST00000463916.1
ENST00000544157.1
XRN1
5'-3' exoribonuclease 1
chr1_+_120049826 0.13 ENST00000369413.3
ENST00000235547.6
ENST00000528909.1
HSD3B1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
chr13_+_24844819 0.13 ENST00000399949.2
SPATA13
spermatogenesis associated 13
chr3_+_63897605 0.13 ENST00000487717.1
ATXN7
ataxin 7
chr12_-_31882027 0.13 ENST00000541931.1
ENST00000535408.1
AMN1
antagonist of mitotic exit network 1 homolog (S. cerevisiae)
chr5_-_36301984 0.13 ENST00000502994.1
ENST00000515759.1
ENST00000296604.3
RANBP3L
RAN binding protein 3-like
chr2_-_3504587 0.13 ENST00000415131.1
ADI1
acireductone dioxygenase 1
chr2_+_217082311 0.13 ENST00000597904.1
RP11-566E18.3
RP11-566E18.3
chr12_-_67197760 0.13 ENST00000539540.1
ENST00000540433.1
ENST00000541947.1
ENST00000538373.1
GRIP1
glutamate receptor interacting protein 1
chr7_-_53879623 0.12 ENST00000380970.2
GS1-179L18.1
GS1-179L18.1
chr9_+_125027127 0.12 ENST00000441707.1
ENST00000373723.5
ENST00000373729.1
MRRF
mitochondrial ribosome recycling factor
chr21_+_30502806 0.12 ENST00000399928.1
ENST00000399926.1
MAP3K7CL
MAP3K7 C-terminal like
chr7_+_76139741 0.12 ENST00000334348.3
ENST00000419923.2
ENST00000448265.3
ENST00000443097.2
UPK3B
uroplakin 3B
chr3_-_52569023 0.12 ENST00000307076.4
NT5DC2
5'-nucleotidase domain containing 2
chr21_+_30503282 0.12 ENST00000399925.1
MAP3K7CL
MAP3K7 C-terminal like
chr17_+_76374714 0.12 ENST00000262764.6
ENST00000589689.1
ENST00000329897.7
ENST00000592043.1
ENST00000587356.1
PGS1
phosphatidylglycerophosphate synthase 1
chr8_+_11666649 0.12 ENST00000528643.1
ENST00000525777.1
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr2_-_225811747 0.12 ENST00000409592.3
DOCK10
dedicator of cytokinesis 10
chr1_-_2323140 0.12 ENST00000378531.3
ENST00000378529.3
MORN1
MORN repeat containing 1
chr5_-_58882219 0.12 ENST00000505453.1
ENST00000360047.5
PDE4D
phosphodiesterase 4D, cAMP-specific
chr11_+_8932828 0.12 ENST00000530281.1
ENST00000396648.2
ENST00000534147.1
ENST00000529942.1
AKIP1
A kinase (PRKA) interacting protein 1
chr7_+_29234375 0.11 ENST00000409350.1
ENST00000495789.2
ENST00000539389.1
CHN2
chimerin 2
chr16_+_27413483 0.11 ENST00000337929.3
ENST00000564089.1
IL21R
interleukin 21 receptor
chr1_+_207262627 0.11 ENST00000391923.1
C4BPB
complement component 4 binding protein, beta
chr1_-_247171347 0.11 ENST00000339986.7
ENST00000487338.2
ZNF695
zinc finger protein 695
chr16_-_89556942 0.11 ENST00000301030.4
ANKRD11
ankyrin repeat domain 11
chr2_+_10560147 0.11 ENST00000422133.1
HPCAL1
hippocalcin-like 1
chrX_-_148713440 0.11 ENST00000536359.1
ENST00000316916.8
TMEM185A
transmembrane protein 185A
chr6_-_86099898 0.11 ENST00000455071.1
RP11-30P6.6
RP11-30P6.6
chr3_-_33481835 0.11 ENST00000283629.3
UBP1
upstream binding protein 1 (LBP-1a)
chr11_-_107729504 0.11 ENST00000265836.7
SLC35F2
solute carrier family 35, member F2
chr14_-_21994525 0.11 ENST00000538754.1
SALL2
spalt-like transcription factor 2
chr2_-_179914760 0.10 ENST00000420890.2
ENST00000409284.1
ENST00000443758.1
ENST00000446116.1
CCDC141
coiled-coil domain containing 141
chr3_+_183899770 0.10 ENST00000442686.1
AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr9_-_123639600 0.10 ENST00000373896.3
PHF19
PHD finger protein 19
chr12_+_95611536 0.10 ENST00000549002.1
VEZT
vezatin, adherens junctions transmembrane protein
chr19_+_49375649 0.10 ENST00000200453.5
PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr3_+_9691117 0.10 ENST00000353332.5
ENST00000420925.1
ENST00000296003.4
ENST00000351233.5
MTMR14
myotubularin related protein 14
chr17_+_13972807 0.10 ENST00000429152.2
ENST00000261643.3
ENST00000536205.1
ENST00000537334.1
COX10
cytochrome c oxidase assembly homolog 10 (yeast)
chr1_-_179112173 0.10 ENST00000408940.3
ENST00000504405.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr5_+_118407053 0.10 ENST00000311085.8
ENST00000539542.1
DMXL1
Dmx-like 1
chr2_-_242242133 0.10 ENST00000430918.1
HDLBP
high density lipoprotein binding protein
chr15_-_37391614 0.10 ENST00000219869.9
MEIS2
Meis homeobox 2
chr15_-_78112553 0.10 ENST00000562933.1
LINGO1
leucine rich repeat and Ig domain containing 1
chr1_+_110577229 0.10 ENST00000369795.3
ENST00000369794.2
STRIP1
striatin interacting protein 1
chr2_-_152589670 0.10 ENST00000604864.1
ENST00000603639.1
NEB
nebulin
chr19_+_49496705 0.10 ENST00000595090.1
RUVBL2
RuvB-like AAA ATPase 2
chr1_-_54872059 0.09 ENST00000371320.3
SSBP3
single stranded DNA binding protein 3
chr4_+_128886584 0.09 ENST00000513371.1
C4orf29
chromosome 4 open reading frame 29
chr16_+_50776021 0.09 ENST00000566679.2
ENST00000564634.1
ENST00000398568.2
CYLD
cylindromatosis (turban tumor syndrome)
chr17_+_38296576 0.09 ENST00000264645.7
CASC3
cancer susceptibility candidate 3
chr1_-_179112189 0.09 ENST00000512653.1
ENST00000344730.3
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr1_-_32384693 0.09 ENST00000602683.1
ENST00000470404.1
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr16_-_2260834 0.09 ENST00000562360.1
ENST00000566018.1
BRICD5
BRICHOS domain containing 5
chrX_+_135730373 0.09 ENST00000370628.2
CD40LG
CD40 ligand
chr16_+_20817926 0.09 ENST00000565340.1
AC004381.6
Putative RNA exonuclease NEF-sp
chr6_+_163148973 0.09 ENST00000366888.2
PACRG
PARK2 co-regulated
chr8_-_67090825 0.09 ENST00000276571.3
CRH
corticotropin releasing hormone
chr1_-_247335269 0.09 ENST00000543802.2
ENST00000491356.1
ENST00000472531.1
ENST00000340684.6
ZNF124
zinc finger protein 124
chr3_+_57875711 0.09 ENST00000442599.2
SLMAP
sarcolemma associated protein
chr6_-_84418432 0.09 ENST00000519825.1
ENST00000523484.2
SNAP91
synaptosomal-associated protein, 91kDa
chr1_-_45672221 0.09 ENST00000359600.5
ZSWIM5
zinc finger, SWIM-type containing 5
chr17_+_78518617 0.09 ENST00000537330.1
ENST00000570891.1
RPTOR
regulatory associated protein of MTOR, complex 1
chr9_+_123884038 0.09 ENST00000373847.1
CNTRL
centriolin
chr22_+_35776354 0.09 ENST00000412893.1
HMOX1
heme oxygenase (decycling) 1
chr20_-_33872548 0.09 ENST00000374443.3
EIF6
eukaryotic translation initiation factor 6
chr12_+_57522692 0.09 ENST00000554174.1
LRP1
low density lipoprotein receptor-related protein 1
chr12_-_71003568 0.09 ENST00000547715.1
ENST00000451516.2
ENST00000538708.1
ENST00000550857.1
ENST00000261266.5
PTPRB
protein tyrosine phosphatase, receptor type, B
chr4_-_175443943 0.09 ENST00000296522.6
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr5_-_81046841 0.09 ENST00000509013.2
ENST00000505980.1
ENST00000509053.1
SSBP2
single-stranded DNA binding protein 2
chr10_-_16859442 0.09 ENST00000602389.1
ENST00000345264.5
RSU1
Ras suppressor protein 1
chr1_+_171217622 0.08 ENST00000433267.1
ENST00000367750.3
FMO1
flavin containing monooxygenase 1
chr11_-_46867780 0.08 ENST00000529230.1
ENST00000415402.1
ENST00000312055.5
CKAP5
cytoskeleton associated protein 5
chr14_-_21492251 0.08 ENST00000554398.1
NDRG2
NDRG family member 2
chrX_+_135730297 0.08 ENST00000370629.2
CD40LG
CD40 ligand
chr16_+_4896659 0.08 ENST00000592120.1
UBN1
ubinuclein 1
chr12_+_69201923 0.08 ENST00000462284.1
ENST00000258149.5
ENST00000356290.4
ENST00000540827.1
ENST00000428863.2
ENST00000393412.3
MDM2
MDM2 oncogene, E3 ubiquitin protein ligase
chr17_-_35969409 0.08 ENST00000394378.2
ENST00000585472.1
ENST00000591288.1
ENST00000502449.2
ENST00000345615.4
ENST00000346661.4
ENST00000585689.1
ENST00000339208.6
SYNRG
synergin, gamma
chr6_-_24489842 0.08 ENST00000230036.1
GPLD1
glycosylphosphatidylinositol specific phospholipase D1
chr10_-_79398127 0.08 ENST00000372443.1
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr21_+_38792602 0.08 ENST00000398960.2
ENST00000398956.2
DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr19_-_45663408 0.08 ENST00000317951.4
NKPD1
NTPase, KAP family P-loop domain containing 1
chr5_+_40841276 0.08 ENST00000254691.5
CARD6
caspase recruitment domain family, member 6
chr1_+_149824160 0.08 ENST00000403683.1
HIST2H3A
histone cluster 2, H3a
chr2_-_175260368 0.08 ENST00000342016.3
ENST00000362053.5
CIR1
corepressor interacting with RBPJ, 1
chr22_+_50946645 0.08 ENST00000420993.2
ENST00000395698.3
ENST00000395701.3
ENST00000523045.1
ENST00000299821.11
NCAPH2
non-SMC condensin II complex, subunit H2
chr7_-_156685841 0.08 ENST00000354505.4
ENST00000540390.1
LMBR1
limb development membrane protein 1
chr16_+_20818020 0.08 ENST00000564274.1
ENST00000563068.1
AC004381.6
Putative RNA exonuclease NEF-sp
chr8_-_8318847 0.08 ENST00000521218.1
CTA-398F10.2
CTA-398F10.2
chr6_-_163148700 0.07 ENST00000366894.1
ENST00000338468.3
PARK2
parkin RBR E3 ubiquitin protein ligase
chr5_-_55008101 0.07 ENST00000506624.1
ENST00000513275.1
ENST00000513993.1
SLC38A9
solute carrier family 38, member 9
chr19_-_13044494 0.07 ENST00000593021.1
ENST00000587981.1
ENST00000423140.2
ENST00000314606.4
FARSA
phenylalanyl-tRNA synthetase, alpha subunit

Network of associatons between targets according to the STRING database.

First level regulatory network of PKNOX1_TGIF2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.2 1.4 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.1 1.0 GO:0023021 termination of signal transduction(GO:0023021)
0.1 0.4 GO:0098582 innate vocalization behavior(GO:0098582)
0.1 0.3 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.1 0.3 GO:1903414 spleen trabecula formation(GO:0060345) iron cation export(GO:1903414) ferrous iron export(GO:1903988)
0.1 0.2 GO:0016260 selenocysteine biosynthetic process(GO:0016260)
0.1 0.3 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.1 0.5 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 0.2 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587)
0.1 0.2 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.2 GO:0071409 cellular response to cycloheximide(GO:0071409)
0.0 0.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.0 0.2 GO:0009236 cobalamin biosynthetic process(GO:0009236)
0.0 0.2 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.0 0.2 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.3 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.0 0.3 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.1 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.1 GO:2000742 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.0 0.1 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.1 GO:2000852 corticosterone secretion(GO:0035934) cellular response to cocaine(GO:0071314) positive regulation of fear response(GO:1903367) regulation of corticosterone secretion(GO:2000852) positive regulation of behavioral fear response(GO:2000987)
0.0 0.2 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.0 0.6 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 0.2 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 0.1 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.0 0.1 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.1 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.2 GO:0006740 NADPH regeneration(GO:0006740)
0.0 0.2 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.0 0.1 GO:0016259 seryl-tRNA aminoacylation(GO:0006434) selenocysteine metabolic process(GO:0016259)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0010982 negative regulation of triglyceride catabolic process(GO:0010897) regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.2 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.0 GO:0036215 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.1 GO:0050960 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.0 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.0 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.0 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.0 0.1 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.0 GO:0030070 insulin processing(GO:0030070)
0.0 0.1 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.1 GO:0035720 intraciliary anterograde transport(GO:0035720)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.8 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.2 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.1 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0043196 varicosity(GO:0043196)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1 0.3 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.1 0.3 GO:0097689 iron channel activity(GO:0097689)
0.1 1.0 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 0.2 GO:0019808 polyamine binding(GO:0019808)
0.1 0.2 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 0.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.2 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.4 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.2 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.1 GO:0016652 NAD(P)+ transhydrogenase activity(GO:0008746) oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor(GO:0016652)
0.0 0.1 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.0 0.1 GO:0004676 3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.2 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 0.3 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.2 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.1 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.0 0.1 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.2 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.1 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.1 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.1 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.6 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.6 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.2 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.6 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 1.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.1 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism